TY  - JOUR
A1  - Warrington, Nicole
A1  - Beaumont, Robin
A1  - Horikoshi, Momoko
A1  - Day, Felix R.
A1  - Helgeland, Øyvind
A1  - Laurin, Charles
A1  - Bacelis, Jonas
A1  - Peng, Shouneng
A1  - Hao, Ke
A1  - Feenstra, Bjarke
A1  - Wood, Andrew R.
A1  - Mahajan, Anubha
A1  - Tyrrell, Jessica
A1  - Robertson, Neil R.
A1  - Rayner, N. William
A1  - Qiao, Zhen
A1  - Moen, Gunn-Helen
A1  - Vaudel, Marc
A1  - Marsit, Carmen
A1  - Chen, Jia
A1  - Nodzenski, Michael
A1  - Schnurr, Theresia M.
A1  - Zafarmand, Mohammad Hadi
A1  - Bradfield, Jonathan P.
A1  - Grarup, Niels
A1  - Kooijman, Marjolein N.
A1  - Li-Gao, Ruifang
A1  - Geller, Frank
A1  - Ahluwalia, Tarunveer Singh
A1  - Paternoster, Lavinia
A1  - Rueedi, Rico
A1  - Huikari, Ville
A1  - Hottenga, Jouke-Jan
A1  - Lyytikäinen, Leo-Pekka
A1  - Cavadino, Alana
A1  - Metrustry, Sarah
A1  - Cousminer, Diana L.
A1  - Wu, Ying
A1  - Thiering, Elisabeth Paula
A1  - Wang, Carol A.
A1  - Have, Christian Theil
A1  - Vilor-Tejedor, Natalia
A1  - Joshi, Peter K.
A1  - Painter, Jodie N.
A1  - Ntalla, Ioanna
A1  - Myhre, Ronny
A1  - Pitkänen, Niina
A1  - van Leeuwen, Elisabeth M.
A1  - Joro, Raimo
A1  - Lagou, Vasiliki
A1  - Richmond, Rebecca C.
A1  - Espinosa, Ana
A1  - Barton, Sheila J.
A1  - Inskip, Hazel M.
A1  - Holloway, John W.
A1  - Santa-Marina, Loreto
A1  - Estivill, Xavier
A1  - Ang, Wei
A1  - Marsh, Julie A.
A1  - Reichetzeder, Christoph
A1  - Marullo, Letizia
A1  - Hocher, Berthold
A1  - Lunetta, Kathryn L.
A1  - Murabito, Joanne M.
A1  - Relton, Caroline L.
A1  - Kogevinas, Manolis
A1  - Chatzi, Leda
A1  - Allard, Catherine
A1  - Bouchard, Luigi
A1  - Hivert, Marie-France
A1  - Zhang, Ge
A1  - Muglia, Louis J.
A1  - Heikkinen, Jani
A1  - Morgen, Camilla S.
A1  - van Kampen, Antoine H. C.
A1  - van Schaik, Barbera D. C.
A1  - Mentch, Frank D.
A1  - Langenberg, Claudia
A1  - Scott, Robert A.
A1  - Zhao, Jing Hua
A1  - Hemani, Gibran
A1  - Ring, Susan M.
A1  - Bennett, Amanda J.
A1  - Gaulton, Kyle J.
A1  - Fernandez-Tajes, Juan
A1  - van Zuydam, Natalie R.
A1  - Medina-Gomez, Carolina
A1  - de Haan, Hugoline G.
A1  - Rosendaal, Frits R.
A1  - Kutalik, Zoltán
A1  - Marques-Vidal, Pedro
A1  - Das, Shikta
A1  - Willemsen, Gonneke
A1  - Mbarek, Hamdi
A1  - Müller-Nurasyid, Martina
A1  - Standl, Marie
A1  - Appel, Emil V. R.
A1  - Fonvig, Cilius Esmann
A1  - Trier, Caecilie
A1  - van Beijsterveldt, Catharina E. M.
A1  - Murcia, Mario
A1  - Bustamante, Mariona
A1  - Bonàs-Guarch, Sílvia
A1  - Hougaard, David M.
A1  - Mercader, Josep M.
A1  - Linneberg, Allan
A1  - Schraut, Katharina E.
A1  - Lind, Penelope A.
A1  - Medland, Sarah Elizabeth
A1  - Shields, Beverley M.
A1  - Knight, Bridget A.
A1  - Chai, Jin-Fang
A1  - Panoutsopoulou, Kalliope
A1  - Bartels, Meike
A1  - Sánchez, Friman
A1  - Stokholm, Jakob
A1  - Torrents, David
A1  - Vinding, Rebecca K.
A1  - Willems, Sara M.
A1  - Atalay, Mustafa
A1  - Chawes, Bo L.
A1  - Kovacs, Peter
A1  - Prokopenko, Inga
A1  - Tuke, Marcus A.
A1  - Yaghootkar, Hanieh
A1  - Ruth, Katherine S.
A1  - Jones, Samuel E.
A1  - Loh, Po-Ru
A1  - Murray, Anna
A1  - Weedon, Michael N.
A1  - Tönjes, Anke
A1  - Stumvoll, Michael
A1  - Michaelsen, Kim Fleischer
A1  - Eloranta, Aino-Maija
A1  - Lakka, Timo A.
A1  - van Duijn, Cornelia M.
A1  - Kiess, Wieland
A1  - Koerner, Antje
A1  - Niinikoski, Harri
A1  - Pahkala, Katja
A1  - Raitakari, Olli T.
A1  - Jacobsson, Bo
A1  - Zeggini, Eleftheria
A1  - Dedoussis, George V.
A1  - Teo, Yik-Ying
A1  - Saw, Seang-Mei
A1  - Montgomery, Grant W.
A1  - Campbell, Harry
A1  - Wilson, James F.
A1  - Vrijkotte, Tanja G. M.
A1  - Vrijheid, Martine
A1  - de Geus, Eco J. C. N.
A1  - Hayes, M. Geoffrey
A1  - Kadarmideen, Haja N.
A1  - Holm, Jens-Christian
A1  - Beilin, Lawrence J.
A1  - Pennell, Craig E.
A1  - Heinrich, Joachim
A1  - Adair, Linda S.
A1  - Borja, Judith B.
A1  - Mohlke, Karen L.
A1  - Eriksson, Johan G.
A1  - Widen, Elisabeth E.
A1  - Hattersley, Andrew T.
A1  - Spector, Tim D.
A1  - Kaehoenen, Mika
A1  - Viikari, Jorma S.
A1  - Lehtimaeki, Terho
A1  - Boomsma, Dorret I.
A1  - Sebert, Sylvain
A1  - Vollenweider, Peter
A1  - Sorensen, Thorkild I. A.
A1  - Bisgaard, Hans
A1  - Bonnelykke, Klaus
A1  - Murray, Jeffrey C.
A1  - Melbye, Mads
A1  - Nohr, Ellen A.
A1  - Mook-Kanamori, Dennis O.
A1  - Rivadeneira, Fernando
A1  - Hofman, Albert
A1  - Felix, Janine F.
A1  - Jaddoe, Vincent W. V.
A1  - Hansen, Torben
A1  - Pisinger, Charlotta
A1  - Vaag, Allan A.
A1  - Pedersen, Oluf
A1  - Uitterlinden, Andre G.
A1  - Jarvelin, Marjo-Riitta
A1  - Power, Christine
A1  - Hypponen, Elina
A1  - Scholtens, Denise M.
A1  - Lowe, William L.
A1  - Smith, George Davey
A1  - Timpson, Nicholas J.
A1  - Morris, Andrew P.
A1  - Wareham, Nicholas J.
A1  - Hakonarson, Hakon
A1  - Grant, Struan F. A.
A1  - Frayling, Timothy M.
A1  - Lawlor, Debbie A.
A1  - Njolstad, Pal R.
A1  - Johansson, Stefan
A1  - Ong, Ken K.
A1  - McCarthy, Mark I.
A1  - Perry, John R. B.
A1  - Evans, David M.
A1  - Freathy, Rachel M.
T1  - Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
JF  - Nature genetics
N2  - Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). We used structural equation modeling to decompose the contributions of direct fetal and indirect maternal genetic effects, then applied Mendelian randomization to illuminate causal pathways. For example, both indirect maternal and direct fetal genetic effects drive the observational relationship between lower birth weight and higher later blood pressure: maternal blood pressure-raising alleles reduce offspring birth weight, but only direct fetal effects of these alleles, once inherited, increase later offspring blood pressure. Using maternal birth weight-lowering genotypes to proxy for an adverse intrauterine environment provided no evidence that it causally raises offspring blood pressure, indicating that the inverse birth weight-blood pressure association is attributable to genetic effects, and not to intrauterine programming.
Y1  - 2019
SN  - 1061-4036
SN  - 1546-1718
VL  - 51
IS  - 5
SP  - 804
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - GEN
A1  - Kaminski, Jakob A.
A1  - Schlagenhauf, Florian
A1  - Rapp, Michael A.
A1  - Awasthi, Swapnil
A1  - Ruggeri, Barbara
A1  - Deserno, Lorenz
A1  - Banaschewski, Tobias
A1  - Bokde, Arun L. W.
A1  - Bromberg, Uli
A1  - Büchel, Christian
A1  - Quinlan, Erin Burke
A1  - Desrivières, Sylvane
A1  - Flor, Herta
A1  - Frouin, Vincent
A1  - Garavan, Hugh
A1  - Gowland, Penny
A1  - Ittermann, Bernd
A1  - Martinot, Jean-Luc
A1  - Paillère Martinot, Marie-Laure
A1  - Nees, Frauke
A1  - Papadopoulos Orfanos, Dimitri
A1  - Paus, Tomáš
A1  - Poustka, Luise
A1  - Smolka, Michael N.
A1  - Fröhner, Juliane H.
A1  - Walter, Henrik
A1  - Whelan, Robert
A1  - Ripke, Stephan
A1  - Schumann, Gunter
A1  - Heinz, Andreas
T1  - Epigenetic variance in dopamine D2 receptor
BT  - a marker of IQ malleability?
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Genetic and environmental factors both contribute to cognitive test performance. A substantial increase in average intelligence test results in the second half of the previous century within one generation is unlikely to be explained by genetic changes. One possible explanation for the strong malleability of cognitive performance measure is that environmental factors modify gene expression via epigenetic mechanisms. Epigenetic factors may help to understand the recent observations of an association between dopamine-dependent encoding of reward prediction errors and cognitive capacity, which was modulated by adverse life events. The possible manifestation of malleable biomarkers contributing to variance in cognitive test performance, and thus possibly contributing to the "missing heritability" between estimates from twin studies and variance explained by genetic markers, is still unclear. Here we show in 1475 healthy adolescents from the IMaging and GENetics (IMAGEN) sample that general IQ (gIQ) is associated with (1) polygenic scores for intelligence, (2) epigenetic modification of DRD2 gene, (3) gray matter density in striatum, and (4) functional striatal activation elicited by temporarily surprising reward-predicting cues. Comparing the relative importance for the prediction of gIQ in an overlapping subsample, our results demonstrate neurobiological correlates of the malleability of gIQ and point to equal importance of genetic variance, epigenetic modification of DRD2 receptor gene, as well as functional striatal activation, known to influence dopamine neurotransmission. Peripheral epigenetic markers are in need of confirmation in the central nervous system and should be tested in longitudinal settings specifically assessing individual and environmental factors that modify epigenetic structure.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 950 
KW  - genome-wide association
KW  - reward anticipation
KW  - human intelligence
KW  - human brain
KW  - stress
KW  - metaanalysis
KW  - striatum
KW  - psychopathology
KW  - prediction
KW  - volume
KW  - epigenetics and behaviour
KW  - human behaviour
KW  - learning and memory
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-425687
SN  - 1866-8372
IS  - 950
ER  - 
TY  - JOUR
A1  - Kaminski, Jakob A.
A1  - Schlagenhauf, Florian
A1  - Rapp, Michael A.
A1  - Awasthi, Swapnil
A1  - Ruggeri, Barbara
A1  - Deserno, Lorenz
A1  - Banaschewski, Tobias
A1  - Bokde, Arun L. W.
A1  - Bromberg, Uli
A1  - Büchel, Christian
A1  - Quinlan, Erin Burke
A1  - Desrivieres, Sylvane
A1  - Flor, Herta
A1  - Frouin, Vincent
A1  - Garavan, Hugh
A1  - Gowland, Penny
A1  - Ittermann, Bernd
A1  - Martinot, Jean-Luc
A1  - Martinot, Marie-Laure Paillere
A1  - Nees, Frauke
A1  - Orfanos, Dimitri Papadopoulos
A1  - Paus, Tomas
A1  - Poustka, Luise
A1  - Smolka, Michael N.
A1  - Fröhner, Juliane H.
A1  - Walter, Henrik
A1  - Whelan, Robert
A1  - Ripke, Stephan
A1  - Schumann, Gunter
A1  - Heinz, Andreas
T1  - Epigenetic variance in dopamine D2 receptor
BT  - a marker of IQ malleability?
JF  - Translational Psychiatry
N2  - Genetic and environmental factors both contribute to cognitive test performance. A substantial increase in average intelligence test results in the second half of the previous century within one generation is unlikely to be explained by genetic changes. One possible explanation for the strong malleability of cognitive performance measure is that environmental factors modify gene expression via epigenetic mechanisms. Epigenetic factors may help to understand the recent observations of an association between dopamine-dependent encoding of reward prediction errors and cognitive capacity, which was modulated by adverse life events. The possible manifestation of malleable biomarkers contributing to variance in cognitive test performance, and thus possibly contributing to the "missing heritability" between estimates from twin studies and variance explained by genetic markers, is still unclear. Here we show in 1475 healthy adolescents from the IMaging and GENetics (IMAGEN) sample that general IQ (gIQ) is associated with (1) polygenic scores for intelligence, (2) epigenetic modification of DRD2 gene, (3) gray matter density in striatum, and (4) functional striatal activation elicited by temporarily surprising reward-predicting cues. Comparing the relative importance for the prediction of gIQ in an overlapping subsample, our results demonstrate neurobiological correlates of the malleability of gIQ and point to equal importance of genetic variance, epigenetic modification of DRD2 receptor gene, as well as functional striatal activation, known to influence dopamine neurotransmission. Peripheral epigenetic markers are in need of confirmation in the central nervous system and should be tested in longitudinal settings specifically assessing individual and environmental factors that modify epigenetic structure.
Y1  - 2018
U6  - https://doi.org/10.1038/s41398-018-0222-7
SN  - 2158-3188
VL  - 8
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - GEN
A1  - Kaminski, Jakob
A1  - Schlagenhauf, Florian
A1  - Rapp, Michael A.
A1  - Awasthi, Swapnil
A1  - Ruggeri, Barbara
A1  - Deserno, Lorenz
A1  - Laura, Daedelow
A1  - Banaschewski, Tobias
A1  - Bokde, Arun
A1  - Quinlan, Erin Burke
A1  - Buechel, Christian
A1  - Bromberg, Uli
A1  - Desrivieres, Sylvane
A1  - Flor, Herta
A1  - Frouin, Vincent
A1  - Garavan, Hugh
A1  - Gowland, Penny
A1  - Ittermann, Bernd
A1  - Martinot, Jean-Luc
A1  - Martinot, Marie-Laure Paillere
A1  - Nees, Frauke
A1  - Orfanos, Dimitri Papadopoulos
A1  - Paus, Tomas
A1  - Poustka, Luise
A1  - Smolka, Michael
A1  - Froehner, Juliane
A1  - Walter, Henrik
A1  - Whelan, Robert
A1  - Ripke, Stephan
A1  - Schumann, Gunter
A1  - Heinz, Andreas
T1  - Variance in Dopaminergic Markers
BT  - a possible marker of individual differences in IQ?
T2  - Biological psychiatry : a journal of psychiatric neuroscience and therapeutics ; a publication of the Society of Biological Psychiatry
KW  - Intelligence
KW  - Dopamine
KW  - Epigenetic Biomarkers
KW  - Reward Anticipation
KW  - Polygenic Risk Score
Y1  - 2018
U6  - https://doi.org/10.1016/j.biopsych.2018.02.311
SN  - 0006-3223
SN  - 1873-2402
VL  - 83
IS  - 9
SP  - S118
EP  - S118
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Young, Linda
A1  - Ueda, Kiyoshi
A1  - Gühr, Markus
A1  - Bucksbaum, Philip H.
A1  - Simon, Marc
A1  - Mukamel, Shaul
A1  - Rohringer, Nina
A1  - Prince, Kevin C.
A1  - Masciovecchio, Claudio
A1  - Meyer, Michael
A1  - Rudenko, Artem
A1  - Rolles, Daniel
A1  - Bostedt, Christoph
A1  - Fuchs, Matthias
A1  - Reis, David A.
A1  - Santra, Robin
A1  - Kapteyn, Henry
A1  - Murnane, Margaret
A1  - Ibrahim, Heide
A1  - Legare, Francois
A1  - Vrakking, Marc
A1  - Isinger, Marcus
A1  - Kroon, David
A1  - Gisselbrecht, Mathieu
A1  - Wörner, Hans Jakob
A1  - Leone, Stephen R.
T1  - Roadmap of ultrafast x-ray atomic and molecular physics
JF  - Journal of physics : B, Atomic, molecular and optical physics
N2  - X-ray free-electron lasers (XFELs) and table-top sources of x-rays based upon high harmonic generation (HHG) have revolutionized the field of ultrafast x-ray atomic and molecular physics, largely due to an explosive growth in capabilities in the past decade. XFELs now provide unprecedented intensity (10(20) W cm(-2)) of x-rays at wavelengths down to similar to 1 Angstrom, and HHG provides unprecedented time resolution (similar to 50 attoseconds) and a correspondingly large coherent bandwidth at longer wavelengths. For context, timescales can be referenced to the Bohr orbital period in hydrogen atom of 150 attoseconds and the hydrogen-molecule vibrational period of 8 femtoseconds; wavelength scales can be referenced to the chemically significant carbon K-edge at a photon energy of similar to 280 eV (44 Angstroms) and the bond length in methane of similar to 1 Angstrom. With these modern x-ray sources one now has the ability to focus on individual atoms, even when embedded in a complex molecule, and view electronic and nuclear motion on their intrinsic scales (attoseconds and Angstroms). These sources have enabled coherent diffractive imaging, where one can image non-crystalline objects in three dimensions on ultrafast timescales, potentially with atomic resolution. The unprecedented intensity available with XFELs has opened new fields of multiphoton and nonlinear x-ray physics where behavior of matter under extreme conditions can be explored. The unprecedented time resolution and pulse synchronization provided by HHG sources has kindled fundamental investigations of time delays in photoionization, charge migration in molecules, and dynamics near conical intersections that are foundational to AMO physics and chemistry. This roadmap coincides with the year when three new XFEL facilities, operating at Angstrom wavelengths, opened for users (European XFEL, Swiss-FEL and PAL-FEL in Korea) almost doubling the present worldwide number of XFELs, and documents the remarkable progress in HHG capabilities since its discovery roughly 30 years ago, showcasing experiments in AMO physics and other applications. Here we capture the perspectives of 17 leading groups and organize the contributions into four categories: ultrafast molecular dynamics, multidimensional x-ray spectroscopies; high-intensity x-ray phenomena; attosecond x-ray science.
KW  - ultrafast molecular dynamics
KW  - x-ray spectroscopies and phenomena
KW  - table-top sources
KW  - x-ray free-electron lasers
KW  - attosecond phenomena
Y1  - 2018
U6  - https://doi.org/10.1088/1361-6455/aa9735
SN  - 0953-4075
SN  - 1361-6455
VL  - 51
IS  - 3
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Battegay, Caspar
A1  - Bierwirth, Sabine
A1  - Dubrau, Alexander
A1  - Feinberg, Anat
A1  - Franz-Klauser, Olivia
A1  - Grözinger, Elvira
A1  - Grözinger, Karl E.
A1  - Haußig, Hans-Michael
A1  - Hessing, Jakob
A1  - Horch, Hans-Otto
A1  - Hudak-Laziç, Susanne
A1  - Jütte, Daniel
A1  - Jütte, Robert
A1  - Lutz, Edith
A1  - Madsen, Hendrik
A1  - Riemer, Nathanael
A1  - Schlör, Joachim
ED  - Riemer, Nathanael
T1  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. = Themenheft zum 150. Todestag von Heinrich Heine
N2  - Aus dem Inhalt dieser Ausgabe: Artikel und Miszellen: Karl E. Grözinger: Manfred Voigts zum Sechzigsten - 2.5.2006 Caspar Battegay: Wie nicht erinnern? - Die Frage nach der Jüdischkeit in Heinrich Heines autobiographischen Texten Edith Lutz: Heinrich Heine im "Verein für Cultur und Wissenschaft der Juden" Jakob Hessing: Wahrheit und Dichtung - Die Damaskusaffäre und Heines Der Rabbi von Bacharach Elvira Grözinger: Im Venusberg. Zu Gesundheit und Krankheit bei Heinrich Heine zwischen Eros und Thanatos Sabine Bierwirth: Meilenstein der Zeitgeschichtsschreibung: Heinrich Heines Berichte über die Judenverfolgung in Damaskus 1840 Hans Otto Horch: Die unheilbar große Brüderkrankheit - Zum programmatischen Zeitgedicht Das neue Israelitische Hospital zu Hamburg von H. Heine Hendrik Madsen: Vom Überleben der toten Schrift - Eine medientheoretisch orientierte Lektüre des Jeremiabuches Manfred Voigts: Moses Mendelssohn und Franz Kafka: Die Heilige Schrift Olivia Franz-Klauser: Samaritanerforschung im 19. Jahrhundert: Die Anfänge der historischen Kritik im Schatten religiöser Vorurteile, gezeigt an der Rezeption Moritz Heidenheims (1824-1898) Rezensionen: Mark R. Cohen: Unter Kreuz und Halbmond. Die Juden im Mittelalter (Daniel Jütte) Erika Timm: Historische jiddische Semantik. (Karl E. Grözinger) David B. Ruderman, Giuseppe Veltri (Hrsg.): Cultural Intermediaries. Jewish Intellectuals in Early Modern Italy (Daniel Jütte) Gian Maria Varanini, Reinhold C. Mueller (Hrsg.): Ebrei nella Terraferma veneta del Quattrocento (Daniel Jütte) Stefanie B. Siegmund: The Medici State and the Ghetto of Florence (Daniel Jütte) Johannes Mordstein: Selbstbewußte Untertänigkeit (Robert Jütte) Werner Heegewaldt, Oliver Sander (Hrsg.): Salomo Sachs (Elvira Grözinger) Philipp Theisohn: Die Urbarkeit der Zeichen. Zionismus und Literatur - eine andere Poetik der Moderne (Joachim Schlör) Jascha Nemtsov: Die Neue Jüdische Schule in der Musik (Susanne Hudak-Laziç) Ines Sonder: Gartenstädte in Eretz Israel. (Robert Jütte) Cilly Kugelmann (Hrsg.): Weihnukka. Geschichten von Weihnachten und Chanukka. (Daniel Jütte) Moshe Zimmermann, Yotam Hotam (Hrsg.): Zweimal Heimat. Die Jeckes zwischen Mitteleuropa und Nahost. (Anat Feinberg) Birgit Schlachter: Schreibweisen der Abwesenheit. (Elvira Grözinger) Jüdische Studien in aller Welt: Juden und Judentum im Iran - Einige zufällige und weniger zufällige Reiseeindrücke (Hans-Michael Haußig) Nachrichten Rückblicke
T3  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. - 12 
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-14636
SN  - 978-3-939469-19-3
SN  - 1862-7684
SN  - 1614-6492
IS  - 12
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Kalkuhl, Matthias
A1  - Fernandez Milan, Blanca
A1  - Schwerhoff, Gregor
A1  - Jakob, Michael
A1  - Hahnen, Maren
A1  - Creutzig, Felix
T1  - Can land taxes foster sustainable development?
BT  - An assessment of fiscal, distributional and implementation issues
JF  - Land use policy : the international journal covering all aspects of land use
N2  - Economists argue that land rent taxation is an ideal form of taxation as it causes no deadweight losses. Nevertheless, pure land rent taxation is rarely applied. This paper revisits the case of land taxation for developing countries. We first provide an up-to-date review on land taxation in development countries, including feasibility and implementation challenges. We then simulate land tax reforms for Rwanda, Peru, Nicaragua and Indonesia, based on household surveys. We find that (i) land taxes provide a substantial untapped potential for tax revenues at minimal deadweight losses; that (ii) linear land value taxes tend to put a high relative burden on poor households as land ownership is pervasive; (iii) non-linear tax schemes could avoid adverse effects on the poor; and that (iv) with technological advances, administrative costs of land taxes have reduced substantially and are outweighed by tax revenues and co-benefits of formalized land tenure. Enforcement and compliance remain, however, a key challenge.
KW  - Fiscal policy
KW  - Public economics
KW  - Optimal taxes
KW  - Tax incidence
KW  - Land use
Y1  - 2018
U6  - https://doi.org/10.1016/j.landusepol.2018.07.008
SN  - 0264-8377
SN  - 1873-5754
VL  - 78
SP  - 338
EP  - 352
PB  - Elsevier Science Publishers Ltd.
CY  - Oxford
ER  - 
TY  - JOUR
A1  - van der Meij, Marijn W.
A1  - Reimann, Tony
A1  - Vornehm, V. K.
A1  - Temme, Arnaud J. A. M.
A1  - Wallinga, Jakob
A1  - van Beek, Roy
A1  - Sommer, Michael
T1  - Reconstructing rates and patterns of colluvial soil redistribution in agrarian (hummocky) landscapes
JF  - Earth surface processes and landforms : the journal of the British Geomorphological Research Group
N2  - Humans have triggered or accelerated erosion processes since prehistoric times through agricultural practices. Optically stimulated luminescence (OSL) is widely used to quantify phases and rates of the corresponding landscape change, by measuring the last moment of daylight exposure of sediments. However, natural and anthropogenic mixing processes, such as bioturbation and tillage, complicate the use of OSL as grains of different depositional ages become mixed, and grains become exposed to light even long after the depositional event of interest. Instead, OSL determines the stabilization age, indicating when sediments were buried below the active mixing zone. These stabilization ages can cause systematic underestimation when calculating deposition rates. Our focus is on colluvial deposition in a kettle hole in the Uckermark region, northeastern Germany. We took 32 samples from five locations in the colluvium filling the kettle hole to study both spatial and temporal patterns in colluviation. We combined OSL dating with advanced age modelling to determine the stabilization age of colluvial sediments. These ages were combined with an archaeological reconstruction of historical ploughing depths to derive the levels of the soil surface at the moment of stabilization; the deposition depths, which were then used to calculate unbiased deposition rates. We identified two phases of colluvial deposition. The oldest deposits (similar to 5 ka) were located at the fringe of the kettle hole and accumulated relatively slowly, whereas the youngest deposits (<0.3 ka) rapidly filled the central kettle hole with rates of two orders of magnitude higher. We suggest that the latter phase is related to artificial drainage, facilitating accessibility in the central depression for agricultural practices. Our results show the need for numerical dating techniques that take archaeological and soil-geomorphological information into account to identify spatiotemporal patterns of landscape change, and to correctly interpret landscape dynamics in anthropogenically influenced hilly landscapes. (c) 2019 The Authors. Earth Surface Processes and Landforms Published by John Wiley & Sons Ltd.
KW  - geochronology
KW  - OSL
KW  - tillage
KW  - erosion
KW  - kettle hole
KW  - hummocky
KW  - landscape evolution
Y1  - 2019
U6  - https://doi.org/10.1002/esp.4671
SN  - 0197-9337
SN  - 1096-9837
VL  - 44
IS  - 12
SP  - 2408
EP  - 2422
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Feger, Martina
A1  - Fajol, Abul
A1  - Lebedeva, Aleksandra
A1  - Meissner, Adrian
A1  - Michael, Diana
A1  - Völkl, Jakob
A1  - Alesutan, Ioana
A1  - Schleicher, Erwin
A1  - Reichetzeder, Christoph
A1  - Hocher, Berthold
A1  - Qadri, Syed M.
A1  - Lang, Florian
T1  - Effect of Carbon Monoxide Donor CORM-2 on Vitamin D-3 Metabolism
JF  - Kidney & blood pressure research : official organ of the Gesellschaft für Nephrologie
N2  - Background/Aims: Carbon monoxide (CO) interferes with cytochrome-dependent cellular functions and acts as gaseous transmitter. CO is released from CO-releasing molecules (CORM) including tricarbonyl-dichlororuthenium (II) dimer (CORM-2), molecules considered for the treatment of several disorders including vascular dysfunction, inflammation, tissue ischemia and organ rejection. Cytochrome P450-sensitive function include formation of 1,25-dihydroxyvitamin D-3 (1,25(OH)(2)D-3) by renal 25-hydroxyvitamin D-3 1-alpha-hydroxylase (Cyp27b1). The enzyme is regulated by PTH, FGF23 and klotho. 1,25(OH)(2)D-3 regulates Ca2+ and phosphate transport as well as klotho expression. The present study explored, whether CORM-2 influences 1,25(OH)(2)D-3 formation and klotho expression. Methods: Mice were treated with intravenous CORM-2 (20 mg/kg body weight). Plasma 1,25(OH)(2)D-3 and FGF23 concentrations were determined by ELISA, phosphate, calcium and creatinine concentrations by colorimetric methods, transcript levels by quantitative RT-PCR and protein expression by western blotting. Fgf23 mRNA transcript levels were further determined in rat osteosarcoma UMR106 cells without or with prior treatment for 24 hours with 20 mu M CORM-2. Results: CORM-2 injection within 24 hours significantly increased FGF23 plasma levels and decreased 1,25(OH)(2)D-3 plasma levels, renal Cyp27b1 gene expression as well as renal klotho protein abundance and transcript levels. Moreover, treatment of UMR106 cells with CORM-2 significantly increased Fgf23 transcript levels. Conclusion: CO-releasing molecule CORM-2 enhances FGF23 expression and release and decreases klotho expression and 1,25(OH)(2)D-3 synthesis.
KW  - CORM-2
KW  - 1,25-Dihydroxyvitamin D-3
KW  - Klotho
KW  - FGF23
KW  - Phosphate
KW  - Calcium
Y1  - 2013
U6  - https://doi.org/10.1159/000355730
SN  - 1420-4096
SN  - 1423-0143
VL  - 37
IS  - 4-5
SP  - 496
EP  - 505
PB  - Karger
CY  - Basel
ER  - 
TY  - JOUR
A1  - Reichstein, Markus
A1  - Bahn, Michael
A1  - Ciais, Philippe
A1  - Frank, Dorothea
A1  - Mahecha, Miguel D.
A1  - Seneviratne, Sonia I.
A1  - Zscheischler, Jakob
A1  - Beer, Christian
A1  - Buchmann, Nina
A1  - Frank, David C.
A1  - Papale, Dario
A1  - Rammig, Anja
A1  - Smith, Pete
A1  - Thonicke, Kirsten
A1  - van der Velde, Marijn
A1  - Vicca, Sara
A1  - Walz, Ariane
A1  - Wattenbach, Martin
T1  - Climate extremes and the carbon cycle
JF  - Nature : the international weekly journal of science
N2  - The terrestrial biosphere is a key component of the global carbon cycle and its carbon balance is strongly influenced by climate. Continuing environmental changes are thought to increase global terrestrial carbon uptake. But evidence is mounting that climate extremes such as droughts or storms can lead to a decrease in regional ecosystem carbon stocks and therefore have the potential to negate an expected increase in terrestrial carbon uptake. Here we explore the mechanisms and impacts of climate extremes on the terrestrial carbon cycle, and propose a pathway to improve our understanding of present and future impacts of climate extremes on the terrestrial carbon budget.
Y1  - 2013
U6  - https://doi.org/10.1038/nature12350
SN  - 0028-0836
VL  - 500
IS  - 7462
SP  - 287
EP  - 295
PB  - Nature Publ. Group
CY  - London
ER  -