TY  - JOUR
A1  - Warrington, Nicole
A1  - Beaumont, Robin
A1  - Horikoshi, Momoko
A1  - Day, Felix R.
A1  - Helgeland, Øyvind
A1  - Laurin, Charles
A1  - Bacelis, Jonas
A1  - Peng, Shouneng
A1  - Hao, Ke
A1  - Feenstra, Bjarke
A1  - Wood, Andrew R.
A1  - Mahajan, Anubha
A1  - Tyrrell, Jessica
A1  - Robertson, Neil R.
A1  - Rayner, N. William
A1  - Qiao, Zhen
A1  - Moen, Gunn-Helen
A1  - Vaudel, Marc
A1  - Marsit, Carmen
A1  - Chen, Jia
A1  - Nodzenski, Michael
A1  - Schnurr, Theresia M.
A1  - Zafarmand, Mohammad Hadi
A1  - Bradfield, Jonathan P.
A1  - Grarup, Niels
A1  - Kooijman, Marjolein N.
A1  - Li-Gao, Ruifang
A1  - Geller, Frank
A1  - Ahluwalia, Tarunveer Singh
A1  - Paternoster, Lavinia
A1  - Rueedi, Rico
A1  - Huikari, Ville
A1  - Hottenga, Jouke-Jan
A1  - Lyytikäinen, Leo-Pekka
A1  - Cavadino, Alana
A1  - Metrustry, Sarah
A1  - Cousminer, Diana L.
A1  - Wu, Ying
A1  - Thiering, Elisabeth Paula
A1  - Wang, Carol A.
A1  - Have, Christian Theil
A1  - Vilor-Tejedor, Natalia
A1  - Joshi, Peter K.
A1  - Painter, Jodie N.
A1  - Ntalla, Ioanna
A1  - Myhre, Ronny
A1  - Pitkänen, Niina
A1  - van Leeuwen, Elisabeth M.
A1  - Joro, Raimo
A1  - Lagou, Vasiliki
A1  - Richmond, Rebecca C.
A1  - Espinosa, Ana
A1  - Barton, Sheila J.
A1  - Inskip, Hazel M.
A1  - Holloway, John W.
A1  - Santa-Marina, Loreto
A1  - Estivill, Xavier
A1  - Ang, Wei
A1  - Marsh, Julie A.
A1  - Reichetzeder, Christoph
A1  - Marullo, Letizia
A1  - Hocher, Berthold
A1  - Lunetta, Kathryn L.
A1  - Murabito, Joanne M.
A1  - Relton, Caroline L.
A1  - Kogevinas, Manolis
A1  - Chatzi, Leda
A1  - Allard, Catherine
A1  - Bouchard, Luigi
A1  - Hivert, Marie-France
A1  - Zhang, Ge
A1  - Muglia, Louis J.
A1  - Heikkinen, Jani
A1  - Morgen, Camilla S.
A1  - van Kampen, Antoine H. C.
A1  - van Schaik, Barbera D. C.
A1  - Mentch, Frank D.
A1  - Langenberg, Claudia
A1  - Scott, Robert A.
A1  - Zhao, Jing Hua
A1  - Hemani, Gibran
A1  - Ring, Susan M.
A1  - Bennett, Amanda J.
A1  - Gaulton, Kyle J.
A1  - Fernandez-Tajes, Juan
A1  - van Zuydam, Natalie R.
A1  - Medina-Gomez, Carolina
A1  - de Haan, Hugoline G.
A1  - Rosendaal, Frits R.
A1  - Kutalik, Zoltán
A1  - Marques-Vidal, Pedro
A1  - Das, Shikta
A1  - Willemsen, Gonneke
A1  - Mbarek, Hamdi
A1  - Müller-Nurasyid, Martina
A1  - Standl, Marie
A1  - Appel, Emil V. R.
A1  - Fonvig, Cilius Esmann
A1  - Trier, Caecilie
A1  - van Beijsterveldt, Catharina E. M.
A1  - Murcia, Mario
A1  - Bustamante, Mariona
A1  - Bonàs-Guarch, Sílvia
A1  - Hougaard, David M.
A1  - Mercader, Josep M.
A1  - Linneberg, Allan
A1  - Schraut, Katharina E.
A1  - Lind, Penelope A.
A1  - Medland, Sarah Elizabeth
A1  - Shields, Beverley M.
A1  - Knight, Bridget A.
A1  - Chai, Jin-Fang
A1  - Panoutsopoulou, Kalliope
A1  - Bartels, Meike
A1  - Sánchez, Friman
A1  - Stokholm, Jakob
A1  - Torrents, David
A1  - Vinding, Rebecca K.
A1  - Willems, Sara M.
A1  - Atalay, Mustafa
A1  - Chawes, Bo L.
A1  - Kovacs, Peter
A1  - Prokopenko, Inga
A1  - Tuke, Marcus A.
A1  - Yaghootkar, Hanieh
A1  - Ruth, Katherine S.
A1  - Jones, Samuel E.
A1  - Loh, Po-Ru
A1  - Murray, Anna
A1  - Weedon, Michael N.
A1  - Tönjes, Anke
A1  - Stumvoll, Michael
A1  - Michaelsen, Kim Fleischer
A1  - Eloranta, Aino-Maija
A1  - Lakka, Timo A.
A1  - van Duijn, Cornelia M.
A1  - Kiess, Wieland
A1  - Koerner, Antje
A1  - Niinikoski, Harri
A1  - Pahkala, Katja
A1  - Raitakari, Olli T.
A1  - Jacobsson, Bo
A1  - Zeggini, Eleftheria
A1  - Dedoussis, George V.
A1  - Teo, Yik-Ying
A1  - Saw, Seang-Mei
A1  - Montgomery, Grant W.
A1  - Campbell, Harry
A1  - Wilson, James F.
A1  - Vrijkotte, Tanja G. M.
A1  - Vrijheid, Martine
A1  - de Geus, Eco J. C. N.
A1  - Hayes, M. Geoffrey
A1  - Kadarmideen, Haja N.
A1  - Holm, Jens-Christian
A1  - Beilin, Lawrence J.
A1  - Pennell, Craig E.
A1  - Heinrich, Joachim
A1  - Adair, Linda S.
A1  - Borja, Judith B.
A1  - Mohlke, Karen L.
A1  - Eriksson, Johan G.
A1  - Widen, Elisabeth E.
A1  - Hattersley, Andrew T.
A1  - Spector, Tim D.
A1  - Kaehoenen, Mika
A1  - Viikari, Jorma S.
A1  - Lehtimaeki, Terho
A1  - Boomsma, Dorret I.
A1  - Sebert, Sylvain
A1  - Vollenweider, Peter
A1  - Sorensen, Thorkild I. A.
A1  - Bisgaard, Hans
A1  - Bonnelykke, Klaus
A1  - Murray, Jeffrey C.
A1  - Melbye, Mads
A1  - Nohr, Ellen A.
A1  - Mook-Kanamori, Dennis O.
A1  - Rivadeneira, Fernando
A1  - Hofman, Albert
A1  - Felix, Janine F.
A1  - Jaddoe, Vincent W. V.
A1  - Hansen, Torben
A1  - Pisinger, Charlotta
A1  - Vaag, Allan A.
A1  - Pedersen, Oluf
A1  - Uitterlinden, Andre G.
A1  - Jarvelin, Marjo-Riitta
A1  - Power, Christine
A1  - Hypponen, Elina
A1  - Scholtens, Denise M.
A1  - Lowe, William L.
A1  - Smith, George Davey
A1  - Timpson, Nicholas J.
A1  - Morris, Andrew P.
A1  - Wareham, Nicholas J.
A1  - Hakonarson, Hakon
A1  - Grant, Struan F. A.
A1  - Frayling, Timothy M.
A1  - Lawlor, Debbie A.
A1  - Njolstad, Pal R.
A1  - Johansson, Stefan
A1  - Ong, Ken K.
A1  - McCarthy, Mark I.
A1  - Perry, John R. B.
A1  - Evans, David M.
A1  - Freathy, Rachel M.
T1  - Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
JF  - Nature genetics
N2  - Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). We used structural equation modeling to decompose the contributions of direct fetal and indirect maternal genetic effects, then applied Mendelian randomization to illuminate causal pathways. For example, both indirect maternal and direct fetal genetic effects drive the observational relationship between lower birth weight and higher later blood pressure: maternal blood pressure-raising alleles reduce offspring birth weight, but only direct fetal effects of these alleles, once inherited, increase later offspring blood pressure. Using maternal birth weight-lowering genotypes to proxy for an adverse intrauterine environment provided no evidence that it causally raises offspring blood pressure, indicating that the inverse birth weight-blood pressure association is attributable to genetic effects, and not to intrauterine programming.
Y1  - 2019
SN  - 1061-4036
SN  - 1546-1718
VL  - 51
IS  - 5
SP  - 804
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - RPRT
A1  - Brodeur, Abel
A1  - Mikola, Derek
A1  - Cook, Nikolai
A1  - Brailey, Thomas
A1  - Briggs, Ryan
A1  - Gendre, Alexandra de
A1  - Dupraz, Yannick
A1  - Fiala, Lenka
A1  - Gabani, Jacopo
A1  - Gauriot, Romain
A1  - Haddad, Joanne
A1  - Lima, Goncalo
A1  - Ankel-Peters, Jörg
A1  - Dreber, Anna
A1  - Campbell, Douglas
A1  - Kattan, Lamis
A1  - Fages, Diego Marino
A1  - Mierisch, Fabian
A1  - Sun, Pu
A1  - Wright, Taylor
A1  - Connolly, Marie
A1  - Hoces de la Guardia, Fernando
A1  - Johannesson, Magnus
A1  - Miguel, Edward
A1  - Vilhuber, Lars
A1  - Abarca, Alejandro
A1  - Acharya, Mahesh
A1  - Adjisse, Sossou Simplice
A1  - Akhtar, Ahwaz
A1  - Lizardi, Eduardo Alberto Ramirez
A1  - Albrecht, Sabina
A1  - Andersen, Synve Nygaard
A1  - Andlib, Zubaria
A1  - Arrora, Falak
A1  - Ash, Thomas
A1  - Bacher, Etienne
A1  - Bachler, Sebastian
A1  - Bacon, Félix
A1  - Bagues, Manuel
A1  - Balogh, Timea
A1  - Batmanov, Alisher
A1  - Barschkett, Mara
A1  - Basdil, B. Kaan
A1  - Dower, Jaromneda
A1  - Castek, Ondrej
A1  - Caviglia-Harris, Jill
A1  - Strand, Gabriella Chauca
A1  - Chen, Shi
A1  - Chzhen, Asya
A1  - Chung, Jong
A1  - Collins, Jason
A1  - Coppock, Alexander
A1  - Cordeau, Hugo
A1  - Couillard, Ben
A1  - Crechet, Jonathan
A1  - Crippa, Lorenzo
A1  - Cui, Jeanne
A1  - Czymara, Christian
A1  - Daarstad, Haley
A1  - Dao, Danh Chi
A1  - Dao, Dong
A1  - Schmandt, Marco David
A1  - Linde, Astrid de
A1  - Melo, Lucas De
A1  - Deer, Lachlan
A1  - Vera, Micole De
A1  - Dimitrova, Velichka
A1  - Dollbaum, Jan Fabian
A1  - Dollbaum, Jan Matti
A1  - Donnelly, Michael
A1  - Huynh, Luu Duc Toan
A1  - Dumbalska, Tsvetomira
A1  - Duncan, Jamie
A1  - Duong, Kiet Tuan
A1  - Duprey, Thibaut
A1  - Dworschak, Christoph
A1  - Ellingsrud, Sigmund
A1  - Elminejad, Ali
A1  - Eissa, Yasmine
A1  - Erhart, Andrea
A1  - Etingin-Frati, Giulian
A1  - Fatemi-Pour, Elaheh
A1  - Federice, Alexa
A1  - Feld, Jan
A1  - Fenig, Guidon
A1  - Firouzjaeiangalougah, Mojtaba
A1  - Fleisje, Erlend
A1  - Fortier-Chouinard, Alexandre
A1  - Engel, Julia Francesca
A1  - Fries, Tilman
A1  - Fortier, Reid
A1  - Fréchet, Nadjim
A1  - Galipeau, Thomas
A1  - Gallegos, Sebastián
A1  - Gangji, Areez
A1  - Gao, Xiaoying
A1  - Garnache, Cloé
A1  - Gáspár, Attila
A1  - Gavrilova, Evelina
A1  - Ghosh, Arijit
A1  - Gibney, Garreth
A1  - Gibson, Grant
A1  - Godager, Geir
A1  - Goff, Leonard
A1  - Gong, Da
A1  - González, Javier
A1  - Gretton, Jeremy
A1  - Griffa, Cristina
A1  - Grigoryeva, Idaliya
A1  - Grtting, Maja
A1  - Guntermann, Eric
A1  - Guo, Jiaqi
A1  - Gugushvili, Alexi
A1  - Habibnia, Hooman
A1  - Häffner, Sonja
A1  - Hall, Jonathan D.
A1  - Hammar, Olle
A1  - Kordt, Amund Hanson
A1  - Hashimoto, Barry
A1  - Hartley, Jonathan S.
A1  - Hausladen, Carina I.
A1  - Havránek, Tomáš
A1  - Hazen, Jacob
A1  - He, Harry
A1  - Hepplewhite, Matthew
A1  - Herrera-Rodriguez, Mario
A1  - Heuer, Felix
A1  - Heyes, Anthony
A1  - Ho, Anson T. Y.
A1  - Holmes, Jonathan
A1  - Holzknecht, Armando
A1  - Hsu, Yu-Hsiang Dexter
A1  - Hu, Shiang-Hung
A1  - Huang, Yu-Shiuan
A1  - Huebener, Mathias
A1  - Huber, Christoph
A1  - Huynh, Kim P.
A1  - Irsova, Zuzana
A1  - Isler, Ozan
A1  - Jakobsson, Niklas
A1  - Frith, Michael James
A1  - Jananji, Raphaël
A1  - Jayalath, Tharaka A.
A1  - Jetter, Michael
A1  - John, Jenny
A1  - Forshaw, Rachel Joy
A1  - Juan, Felipe
A1  - Kadriu, Valon
A1  - Karim, Sunny
A1  - Kelly, Edmund
A1  - Dang, Duy Khanh Hoang
A1  - Khushboo, Tazia
A1  - Kim, Jin
A1  - Kjellsson, Gustav
A1  - Kjelsrud, Anders
A1  - Kotsadam, Andreas
A1  - Korpershoek, Jori
A1  - Krashinsky, Lewis
A1  - Kundu, Suranjana
A1  - Kustov, Alexander
A1  - Lalayev, Nurlan
A1  - Langlois, Audrée
A1  - Laufer, Jill
A1  - Lee-Whiting, Blake
A1  - Leibing, Andreas
A1  - Lenz, Gabriel
A1  - Levin, Joel
A1  - Li, Peng
A1  - Li, Tongzhe
A1  - Lin, Yuchen
A1  - Listo, Ariel
A1  - Liu, Dan
A1  - Lu, Xuewen
A1  - Lukmanova, Elvina
A1  - Luscombe, Alex
A1  - Lusher, Lester R.
A1  - Lyu, Ke
A1  - Ma, Hai
A1  - Mäder, Nicolas
A1  - Makate, Clifton
A1  - Malmberg, Alice
A1  - Maitra, Adit
A1  - Mandas, Marco
A1  - Marcus, Jan
A1  - Margaryan, Shushanik
A1  - Márk, Lili
A1  - Martignano, Andres
A1  - Marsh, Abigail
A1  - Masetto, Isabella
A1  - McCanny, Anthony
A1  - McManus, Emma
A1  - McWay, Ryan
A1  - Metson, Lennard
A1  - Kinge, Jonas Minet
A1  - Mishra, Sumit
A1  - Mohnen, Myra
A1  - Möller, Jakob
A1  - Montambeault, Rosalie
A1  - Montpetit, Sébastien
A1  - Morin, Louis-Philippe
A1  - Morris, Todd
A1  - Moser, Scott
A1  - Motoki, Fabio
A1  - Muehlenbachs, Lucija
A1  - Musulan, Andreea
A1  - Musumeci, Marco
A1  - Nabin, Munirul
A1  - Nchare, Karim
A1  - Neubauer, Florian
A1  - Nguyen, Quan M. P.
A1  - Nguyen, Tuan
A1  - Nguyen-Tien, Viet
A1  - Niazi, Ali
A1  - Nikolaishvili, Giorgi
A1  - Nordstrom, Ardyn
A1  - Nü, Patrick
A1  - Odermatt, Angela
A1  - Olson, Matt
A1  - ien, Henning
A1  - Ölkers, Tim
A1  - Vert, Miquel Oliver i.
A1  - Oral, Emre
A1  - Oswald, Christian
A1  - Ousman, Ali
A1  - Özak, Ömer
A1  - Pandey, Shubham
A1  - Pavlov, Alexandre
A1  - Pelli, Martino
A1  - Penheiro, Romeo
A1  - Park, RyuGyung
A1  - Martel, Eva Pérez
A1  - Petrovičová, Tereza
A1  - Phan, Linh
A1  - Prettyman, Alexa
A1  - Procházka, Jakub
A1  - Putri, Aqila
A1  - Quandt, Julian
A1  - Qiu, Kangyu
A1  - Nguyen, Loan Quynh Thi
A1  - Rahman, Andaleeb
A1  - Rea, Carson H.
A1  - Reiremo, Adam
A1  - Renée, Laëtitia
A1  - Richardson, Joseph
A1  - Rivers, Nicholas
A1  - Rodrigues, Bruno
A1  - Roelofs, William
A1  - Roemer, Tobias
A1  - Rogeberg, Ole
A1  - Rose, Julian
A1  - Roskos-Ewoldsen, Andrew
A1  - Rosmer, Paul
A1  - Sabada, Barbara
A1  - Saberian, Soodeh
A1  - Salamanca, Nicolas
A1  - Sator, Georg
A1  - Sawyer, Antoine
A1  - Scates, Daniel
A1  - Schlüter, Elmar
A1  - Sells, Cameron
A1  - Sen, Sharmi
A1  - Sethi, Ritika
A1  - Shcherbiak, Anna
A1  - Sogaolu, Moyosore
A1  - Soosalu, Matt
A1  - Srensen, Erik
A1  - Sovani, Manali
A1  - Spencer, Noah
A1  - Staubli, Stefan
A1  - Stans, Renske
A1  - Stewart, Anya
A1  - Stips, Felix
A1  - Stockley, Kieran
A1  - Strobel, Stephenson
A1  - Struby, Ethan
A1  - Tang, John
A1  - Tanrisever, Idil
A1  - Yang, Thomas Tao
A1  - Tastan, Ipek
A1  - Tatić, Dejan
A1  - Tatlow, Benjamin
A1  - Seuyong, Féraud Tchuisseu
A1  - Thériault, Rémi
A1  - Thivierge, Vincent
A1  - Tian, Wenjie
A1  - Toma, Filip-Mihai
A1  - Totarelli, Maddalena
A1  - Tran, Van-Anh
A1  - Truong, Hung
A1  - Tsoy, Nikita
A1  - Tuzcuoglu, Kerem
A1  - Ubfal, Diego
A1  - Villalobos, Laura
A1  - Walterskirchen, Julian
A1  - Wang, Joseph Taoyi
A1  - Wattal, Vasudha
A1  - Webb, Matthew D.
A1  - Weber, Bryan
A1  - Weisser, Reinhard
A1  - Weng, Wei-Chien
A1  - Westheide, Christian
A1  - White, Kimberly
A1  - Winter, Jacob
A1  - Wochner, Timo
A1  - Woerman, Matt
A1  - Wong, Jared
A1  - Woodard, Ritchie
A1  - Wroński, Marcin
A1  - Yazbeck, Myra
A1  - Yang, Gustav Chung
A1  - Yap, Luther
A1  - Yassin, Kareman
A1  - Ye, Hao
A1  - Yoon, Jin Young
A1  - Yurris, Chris
A1  - Zahra, Tahreen
A1  - Zaneva, Mirela
A1  - Zayat, Aline
A1  - Zhang, Jonathan
A1  - Zhao, Ziwei
A1  - Yaolang, Zhong
T1  - Mass reproducibility and replicability
BT  - a new hope
T2  - I4R discussion paper series
N2  - This study pushes our understanding of research reliability by reproducing and replicating claims from 110 papers in leading economic and political science journals. The analysis involves computational reproducibility checks and robustness assessments. It reveals several patterns. First, we uncover a high rate of fully computationally reproducible results (over 85%). Second, excluding minor issues like missing packages or broken pathways, we uncover coding errors for about 25% of studies, with some studies containing multiple errors. Third, we test the robustness of the results to 5,511 re-analyses. We find a robustness reproducibility of about 70%. Robustness reproducibility rates are relatively higher for re-analyses that introduce new data and lower for re-analyses that change the sample or the definition of the dependent variable. Fourth, 52% of re-analysis effect size estimates are smaller than the original published estimates and the average statistical significance of a re-analysis is 77% of the original. Lastly, we rely on six teams of researchers working independently to answer eight additional research questions on the determinants of robustness reproducibility. Most teams find a negative relationship between replicators' experience and reproducibility, while finding no relationship between reproducibility and the provision of intermediate or even raw data combined with the necessary cleaning codes.
KW  - conomics
KW  - open science
KW  - political science
KW  - replication
KW  - reproduction
KW  - research transparency
Y1  - 2024
SN  - 2752-1931
IS  - 107
PB  - Institute for Replication
CY  - Essen
ER  - 
TY  - GEN
A1  - Kaminski, Jakob A.
A1  - Schlagenhauf, Florian
A1  - Rapp, Michael A.
A1  - Awasthi, Swapnil
A1  - Ruggeri, Barbara
A1  - Deserno, Lorenz
A1  - Banaschewski, Tobias
A1  - Bokde, Arun L. W.
A1  - Bromberg, Uli
A1  - Büchel, Christian
A1  - Quinlan, Erin Burke
A1  - Desrivières, Sylvane
A1  - Flor, Herta
A1  - Frouin, Vincent
A1  - Garavan, Hugh
A1  - Gowland, Penny
A1  - Ittermann, Bernd
A1  - Martinot, Jean-Luc
A1  - Paillère Martinot, Marie-Laure
A1  - Nees, Frauke
A1  - Papadopoulos Orfanos, Dimitri
A1  - Paus, Tomáš
A1  - Poustka, Luise
A1  - Smolka, Michael N.
A1  - Fröhner, Juliane H.
A1  - Walter, Henrik
A1  - Whelan, Robert
A1  - Ripke, Stephan
A1  - Schumann, Gunter
A1  - Heinz, Andreas
T1  - Epigenetic variance in dopamine D2 receptor
BT  - a marker of IQ malleability?
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Genetic and environmental factors both contribute to cognitive test performance. A substantial increase in average intelligence test results in the second half of the previous century within one generation is unlikely to be explained by genetic changes. One possible explanation for the strong malleability of cognitive performance measure is that environmental factors modify gene expression via epigenetic mechanisms. Epigenetic factors may help to understand the recent observations of an association between dopamine-dependent encoding of reward prediction errors and cognitive capacity, which was modulated by adverse life events. The possible manifestation of malleable biomarkers contributing to variance in cognitive test performance, and thus possibly contributing to the "missing heritability" between estimates from twin studies and variance explained by genetic markers, is still unclear. Here we show in 1475 healthy adolescents from the IMaging and GENetics (IMAGEN) sample that general IQ (gIQ) is associated with (1) polygenic scores for intelligence, (2) epigenetic modification of DRD2 gene, (3) gray matter density in striatum, and (4) functional striatal activation elicited by temporarily surprising reward-predicting cues. Comparing the relative importance for the prediction of gIQ in an overlapping subsample, our results demonstrate neurobiological correlates of the malleability of gIQ and point to equal importance of genetic variance, epigenetic modification of DRD2 receptor gene, as well as functional striatal activation, known to influence dopamine neurotransmission. Peripheral epigenetic markers are in need of confirmation in the central nervous system and should be tested in longitudinal settings specifically assessing individual and environmental factors that modify epigenetic structure.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 950 
KW  - genome-wide association
KW  - reward anticipation
KW  - human intelligence
KW  - human brain
KW  - stress
KW  - metaanalysis
KW  - striatum
KW  - psychopathology
KW  - prediction
KW  - volume
KW  - epigenetics and behaviour
KW  - human behaviour
KW  - learning and memory
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-425687
SN  - 1866-8372
IS  - 950
ER  - 
TY  - JOUR
A1  - Kaminski, Jakob A.
A1  - Schlagenhauf, Florian
A1  - Rapp, Michael A.
A1  - Awasthi, Swapnil
A1  - Ruggeri, Barbara
A1  - Deserno, Lorenz
A1  - Banaschewski, Tobias
A1  - Bokde, Arun L. W.
A1  - Bromberg, Uli
A1  - Büchel, Christian
A1  - Quinlan, Erin Burke
A1  - Desrivieres, Sylvane
A1  - Flor, Herta
A1  - Frouin, Vincent
A1  - Garavan, Hugh
A1  - Gowland, Penny
A1  - Ittermann, Bernd
A1  - Martinot, Jean-Luc
A1  - Martinot, Marie-Laure Paillere
A1  - Nees, Frauke
A1  - Orfanos, Dimitri Papadopoulos
A1  - Paus, Tomas
A1  - Poustka, Luise
A1  - Smolka, Michael N.
A1  - Fröhner, Juliane H.
A1  - Walter, Henrik
A1  - Whelan, Robert
A1  - Ripke, Stephan
A1  - Schumann, Gunter
A1  - Heinz, Andreas
T1  - Epigenetic variance in dopamine D2 receptor
BT  - a marker of IQ malleability?
JF  - Translational Psychiatry
N2  - Genetic and environmental factors both contribute to cognitive test performance. A substantial increase in average intelligence test results in the second half of the previous century within one generation is unlikely to be explained by genetic changes. One possible explanation for the strong malleability of cognitive performance measure is that environmental factors modify gene expression via epigenetic mechanisms. Epigenetic factors may help to understand the recent observations of an association between dopamine-dependent encoding of reward prediction errors and cognitive capacity, which was modulated by adverse life events. The possible manifestation of malleable biomarkers contributing to variance in cognitive test performance, and thus possibly contributing to the "missing heritability" between estimates from twin studies and variance explained by genetic markers, is still unclear. Here we show in 1475 healthy adolescents from the IMaging and GENetics (IMAGEN) sample that general IQ (gIQ) is associated with (1) polygenic scores for intelligence, (2) epigenetic modification of DRD2 gene, (3) gray matter density in striatum, and (4) functional striatal activation elicited by temporarily surprising reward-predicting cues. Comparing the relative importance for the prediction of gIQ in an overlapping subsample, our results demonstrate neurobiological correlates of the malleability of gIQ and point to equal importance of genetic variance, epigenetic modification of DRD2 receptor gene, as well as functional striatal activation, known to influence dopamine neurotransmission. Peripheral epigenetic markers are in need of confirmation in the central nervous system and should be tested in longitudinal settings specifically assessing individual and environmental factors that modify epigenetic structure.
Y1  - 2018
U6  - https://doi.org/10.1038/s41398-018-0222-7
SN  - 2158-3188
VL  - 8
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - GEN
A1  - Kaminski, Jakob
A1  - Schlagenhauf, Florian
A1  - Rapp, Michael A.
A1  - Awasthi, Swapnil
A1  - Ruggeri, Barbara
A1  - Deserno, Lorenz
A1  - Laura, Daedelow
A1  - Banaschewski, Tobias
A1  - Bokde, Arun
A1  - Quinlan, Erin Burke
A1  - Buechel, Christian
A1  - Bromberg, Uli
A1  - Desrivieres, Sylvane
A1  - Flor, Herta
A1  - Frouin, Vincent
A1  - Garavan, Hugh
A1  - Gowland, Penny
A1  - Ittermann, Bernd
A1  - Martinot, Jean-Luc
A1  - Martinot, Marie-Laure Paillere
A1  - Nees, Frauke
A1  - Orfanos, Dimitri Papadopoulos
A1  - Paus, Tomas
A1  - Poustka, Luise
A1  - Smolka, Michael
A1  - Froehner, Juliane
A1  - Walter, Henrik
A1  - Whelan, Robert
A1  - Ripke, Stephan
A1  - Schumann, Gunter
A1  - Heinz, Andreas
T1  - Variance in Dopaminergic Markers
BT  - a possible marker of individual differences in IQ?
T2  - Biological psychiatry : a journal of psychiatric neuroscience and therapeutics ; a publication of the Society of Biological Psychiatry
KW  - Intelligence
KW  - Dopamine
KW  - Epigenetic Biomarkers
KW  - Reward Anticipation
KW  - Polygenic Risk Score
Y1  - 2018
U6  - https://doi.org/10.1016/j.biopsych.2018.02.311
SN  - 0006-3223
SN  - 1873-2402
VL  - 83
IS  - 9
SP  - S118
EP  - S118
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Young, Linda
A1  - Ueda, Kiyoshi
A1  - Gühr, Markus
A1  - Bucksbaum, Philip H.
A1  - Simon, Marc
A1  - Mukamel, Shaul
A1  - Rohringer, Nina
A1  - Prince, Kevin C.
A1  - Masciovecchio, Claudio
A1  - Meyer, Michael
A1  - Rudenko, Artem
A1  - Rolles, Daniel
A1  - Bostedt, Christoph
A1  - Fuchs, Matthias
A1  - Reis, David A.
A1  - Santra, Robin
A1  - Kapteyn, Henry
A1  - Murnane, Margaret
A1  - Ibrahim, Heide
A1  - Legare, Francois
A1  - Vrakking, Marc
A1  - Isinger, Marcus
A1  - Kroon, David
A1  - Gisselbrecht, Mathieu
A1  - Wörner, Hans Jakob
A1  - Leone, Stephen R.
T1  - Roadmap of ultrafast x-ray atomic and molecular physics
JF  - Journal of physics : B, Atomic, molecular and optical physics
N2  - X-ray free-electron lasers (XFELs) and table-top sources of x-rays based upon high harmonic generation (HHG) have revolutionized the field of ultrafast x-ray atomic and molecular physics, largely due to an explosive growth in capabilities in the past decade. XFELs now provide unprecedented intensity (10(20) W cm(-2)) of x-rays at wavelengths down to similar to 1 Angstrom, and HHG provides unprecedented time resolution (similar to 50 attoseconds) and a correspondingly large coherent bandwidth at longer wavelengths. For context, timescales can be referenced to the Bohr orbital period in hydrogen atom of 150 attoseconds and the hydrogen-molecule vibrational period of 8 femtoseconds; wavelength scales can be referenced to the chemically significant carbon K-edge at a photon energy of similar to 280 eV (44 Angstroms) and the bond length in methane of similar to 1 Angstrom. With these modern x-ray sources one now has the ability to focus on individual atoms, even when embedded in a complex molecule, and view electronic and nuclear motion on their intrinsic scales (attoseconds and Angstroms). These sources have enabled coherent diffractive imaging, where one can image non-crystalline objects in three dimensions on ultrafast timescales, potentially with atomic resolution. The unprecedented intensity available with XFELs has opened new fields of multiphoton and nonlinear x-ray physics where behavior of matter under extreme conditions can be explored. The unprecedented time resolution and pulse synchronization provided by HHG sources has kindled fundamental investigations of time delays in photoionization, charge migration in molecules, and dynamics near conical intersections that are foundational to AMO physics and chemistry. This roadmap coincides with the year when three new XFEL facilities, operating at Angstrom wavelengths, opened for users (European XFEL, Swiss-FEL and PAL-FEL in Korea) almost doubling the present worldwide number of XFELs, and documents the remarkable progress in HHG capabilities since its discovery roughly 30 years ago, showcasing experiments in AMO physics and other applications. Here we capture the perspectives of 17 leading groups and organize the contributions into four categories: ultrafast molecular dynamics, multidimensional x-ray spectroscopies; high-intensity x-ray phenomena; attosecond x-ray science.
KW  - ultrafast molecular dynamics
KW  - x-ray spectroscopies and phenomena
KW  - table-top sources
KW  - x-ray free-electron lasers
KW  - attosecond phenomena
Y1  - 2018
U6  - https://doi.org/10.1088/1361-6455/aa9735
SN  - 0953-4075
SN  - 1361-6455
VL  - 51
IS  - 3
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Battegay, Caspar
A1  - Bierwirth, Sabine
A1  - Dubrau, Alexander
A1  - Feinberg, Anat
A1  - Franz-Klauser, Olivia
A1  - Grözinger, Elvira
A1  - Grözinger, Karl E.
A1  - Haußig, Hans-Michael
A1  - Hessing, Jakob
A1  - Horch, Hans-Otto
A1  - Hudak-Laziç, Susanne
A1  - Jütte, Daniel
A1  - Jütte, Robert
A1  - Lutz, Edith
A1  - Madsen, Hendrik
A1  - Riemer, Nathanael
A1  - Schlör, Joachim
ED  - Riemer, Nathanael
T1  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. = Themenheft zum 150. Todestag von Heinrich Heine
N2  - Aus dem Inhalt dieser Ausgabe: Artikel und Miszellen: Karl E. Grözinger: Manfred Voigts zum Sechzigsten - 2.5.2006 Caspar Battegay: Wie nicht erinnern? - Die Frage nach der Jüdischkeit in Heinrich Heines autobiographischen Texten Edith Lutz: Heinrich Heine im "Verein für Cultur und Wissenschaft der Juden" Jakob Hessing: Wahrheit und Dichtung - Die Damaskusaffäre und Heines Der Rabbi von Bacharach Elvira Grözinger: Im Venusberg. Zu Gesundheit und Krankheit bei Heinrich Heine zwischen Eros und Thanatos Sabine Bierwirth: Meilenstein der Zeitgeschichtsschreibung: Heinrich Heines Berichte über die Judenverfolgung in Damaskus 1840 Hans Otto Horch: Die unheilbar große Brüderkrankheit - Zum programmatischen Zeitgedicht Das neue Israelitische Hospital zu Hamburg von H. Heine Hendrik Madsen: Vom Überleben der toten Schrift - Eine medientheoretisch orientierte Lektüre des Jeremiabuches Manfred Voigts: Moses Mendelssohn und Franz Kafka: Die Heilige Schrift Olivia Franz-Klauser: Samaritanerforschung im 19. Jahrhundert: Die Anfänge der historischen Kritik im Schatten religiöser Vorurteile, gezeigt an der Rezeption Moritz Heidenheims (1824-1898) Rezensionen: Mark R. Cohen: Unter Kreuz und Halbmond. Die Juden im Mittelalter (Daniel Jütte) Erika Timm: Historische jiddische Semantik. (Karl E. Grözinger) David B. Ruderman, Giuseppe Veltri (Hrsg.): Cultural Intermediaries. Jewish Intellectuals in Early Modern Italy (Daniel Jütte) Gian Maria Varanini, Reinhold C. Mueller (Hrsg.): Ebrei nella Terraferma veneta del Quattrocento (Daniel Jütte) Stefanie B. Siegmund: The Medici State and the Ghetto of Florence (Daniel Jütte) Johannes Mordstein: Selbstbewußte Untertänigkeit (Robert Jütte) Werner Heegewaldt, Oliver Sander (Hrsg.): Salomo Sachs (Elvira Grözinger) Philipp Theisohn: Die Urbarkeit der Zeichen. Zionismus und Literatur - eine andere Poetik der Moderne (Joachim Schlör) Jascha Nemtsov: Die Neue Jüdische Schule in der Musik (Susanne Hudak-Laziç) Ines Sonder: Gartenstädte in Eretz Israel. (Robert Jütte) Cilly Kugelmann (Hrsg.): Weihnukka. Geschichten von Weihnachten und Chanukka. (Daniel Jütte) Moshe Zimmermann, Yotam Hotam (Hrsg.): Zweimal Heimat. Die Jeckes zwischen Mitteleuropa und Nahost. (Anat Feinberg) Birgit Schlachter: Schreibweisen der Abwesenheit. (Elvira Grözinger) Jüdische Studien in aller Welt: Juden und Judentum im Iran - Einige zufällige und weniger zufällige Reiseeindrücke (Hans-Michael Haußig) Nachrichten Rückblicke
T3  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. - 12 
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-14636
SN  - 978-3-939469-19-3
SN  - 1862-7684
SN  - 1614-6492
IS  - 12
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Kalkuhl, Matthias
A1  - Fernandez Milan, Blanca
A1  - Schwerhoff, Gregor
A1  - Jakob, Michael
A1  - Hahnen, Maren
A1  - Creutzig, Felix
T1  - Can land taxes foster sustainable development?
BT  - An assessment of fiscal, distributional and implementation issues
JF  - Land use policy : the international journal covering all aspects of land use
N2  - Economists argue that land rent taxation is an ideal form of taxation as it causes no deadweight losses. Nevertheless, pure land rent taxation is rarely applied. This paper revisits the case of land taxation for developing countries. We first provide an up-to-date review on land taxation in development countries, including feasibility and implementation challenges. We then simulate land tax reforms for Rwanda, Peru, Nicaragua and Indonesia, based on household surveys. We find that (i) land taxes provide a substantial untapped potential for tax revenues at minimal deadweight losses; that (ii) linear land value taxes tend to put a high relative burden on poor households as land ownership is pervasive; (iii) non-linear tax schemes could avoid adverse effects on the poor; and that (iv) with technological advances, administrative costs of land taxes have reduced substantially and are outweighed by tax revenues and co-benefits of formalized land tenure. Enforcement and compliance remain, however, a key challenge.
KW  - Fiscal policy
KW  - Public economics
KW  - Optimal taxes
KW  - Tax incidence
KW  - Land use
Y1  - 2018
U6  - https://doi.org/10.1016/j.landusepol.2018.07.008
SN  - 0264-8377
SN  - 1873-5754
VL  - 78
SP  - 338
EP  - 352
PB  - Elsevier Science Publishers Ltd.
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Feger, Martina
A1  - Fajol, Abul
A1  - Lebedeva, Aleksandra
A1  - Meissner, Adrian
A1  - Michael, Diana
A1  - Völkl, Jakob
A1  - Alesutan, Ioana
A1  - Schleicher, Erwin
A1  - Reichetzeder, Christoph
A1  - Hocher, Berthold
A1  - Qadri, Syed M.
A1  - Lang, Florian
T1  - Effect of Carbon Monoxide Donor CORM-2 on Vitamin D-3 Metabolism
JF  - Kidney & blood pressure research : official organ of the Gesellschaft für Nephrologie
N2  - Background/Aims: Carbon monoxide (CO) interferes with cytochrome-dependent cellular functions and acts as gaseous transmitter. CO is released from CO-releasing molecules (CORM) including tricarbonyl-dichlororuthenium (II) dimer (CORM-2), molecules considered for the treatment of several disorders including vascular dysfunction, inflammation, tissue ischemia and organ rejection. Cytochrome P450-sensitive function include formation of 1,25-dihydroxyvitamin D-3 (1,25(OH)(2)D-3) by renal 25-hydroxyvitamin D-3 1-alpha-hydroxylase (Cyp27b1). The enzyme is regulated by PTH, FGF23 and klotho. 1,25(OH)(2)D-3 regulates Ca2+ and phosphate transport as well as klotho expression. The present study explored, whether CORM-2 influences 1,25(OH)(2)D-3 formation and klotho expression. Methods: Mice were treated with intravenous CORM-2 (20 mg/kg body weight). Plasma 1,25(OH)(2)D-3 and FGF23 concentrations were determined by ELISA, phosphate, calcium and creatinine concentrations by colorimetric methods, transcript levels by quantitative RT-PCR and protein expression by western blotting. Fgf23 mRNA transcript levels were further determined in rat osteosarcoma UMR106 cells without or with prior treatment for 24 hours with 20 mu M CORM-2. Results: CORM-2 injection within 24 hours significantly increased FGF23 plasma levels and decreased 1,25(OH)(2)D-3 plasma levels, renal Cyp27b1 gene expression as well as renal klotho protein abundance and transcript levels. Moreover, treatment of UMR106 cells with CORM-2 significantly increased Fgf23 transcript levels. Conclusion: CO-releasing molecule CORM-2 enhances FGF23 expression and release and decreases klotho expression and 1,25(OH)(2)D-3 synthesis.
KW  - CORM-2
KW  - 1,25-Dihydroxyvitamin D-3
KW  - Klotho
KW  - FGF23
KW  - Phosphate
KW  - Calcium
Y1  - 2013
U6  - https://doi.org/10.1159/000355730
SN  - 1420-4096
SN  - 1423-0143
VL  - 37
IS  - 4-5
SP  - 496
EP  - 505
PB  - Karger
CY  - Basel
ER  - 
TY  - JOUR
A1  - Reichstein, Markus
A1  - Bahn, Michael
A1  - Ciais, Philippe
A1  - Frank, Dorothea
A1  - Mahecha, Miguel D.
A1  - Seneviratne, Sonia I.
A1  - Zscheischler, Jakob
A1  - Beer, Christian
A1  - Buchmann, Nina
A1  - Frank, David C.
A1  - Papale, Dario
A1  - Rammig, Anja
A1  - Smith, Pete
A1  - Thonicke, Kirsten
A1  - van der Velde, Marijn
A1  - Vicca, Sara
A1  - Walz, Ariane
A1  - Wattenbach, Martin
T1  - Climate extremes and the carbon cycle
JF  - Nature : the international weekly journal of science
N2  - The terrestrial biosphere is a key component of the global carbon cycle and its carbon balance is strongly influenced by climate. Continuing environmental changes are thought to increase global terrestrial carbon uptake. But evidence is mounting that climate extremes such as droughts or storms can lead to a decrease in regional ecosystem carbon stocks and therefore have the potential to negate an expected increase in terrestrial carbon uptake. Here we explore the mechanisms and impacts of climate extremes on the terrestrial carbon cycle, and propose a pathway to improve our understanding of present and future impacts of climate extremes on the terrestrial carbon budget.
Y1  - 2013
U6  - https://doi.org/10.1038/nature12350
SN  - 0028-0836
VL  - 500
IS  - 7462
SP  - 287
EP  - 295
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Frank, Dorothe A.
A1  - Reichstein, Markus
A1  - Bahn, Michael
A1  - Thonicke, Kirsten
A1  - Frank, David
A1  - Mahecha, Miguel D.
A1  - Smith, Pete
A1  - Van der Velde, Marijn
A1  - Vicca, Sara
A1  - Babst, Flurin
A1  - Beer, Christian
A1  - Buchmann, Nina
A1  - Canadell, Josep G.
A1  - Ciais, Philippe
A1  - Cramer, Wolfgang
A1  - Ibrom, Andreas
A1  - Miglietta, Franco
A1  - Poulter, Ben
A1  - Rammig, Anja
A1  - Seneviratne, Sonia I.
A1  - Walz, Ariane
A1  - Wattenbach, Martin
A1  - Zavala, Miguel A.
A1  - Zscheischler, Jakob
T1  - Effects of climate extremes on the terrestrial carbon cycle: concepts, processes and potential future impacts
JF  - Global change biology
N2  - Extreme droughts, heat waves, frosts, precipitation, wind storms and other climate extremes may impact the structure, composition and functioning of terrestrial ecosystems, and thus carbon cycling and its feedbacks to the climate system. Yet, the interconnected avenues through which climate extremes drive ecological and physiological processes and alter the carbon balance are poorly understood. Here, we review the literature on carbon cycle relevant responses of ecosystems to extreme climatic events. Given that impacts of climate extremes are considered disturbances, we assume the respective general disturbance-induced mechanisms and processes to also operate in an extreme context. The paucity of well-defined studies currently renders a quantitative meta-analysis impossible, but permits us to develop a deductive framework for identifying the main mechanisms (and coupling thereof) through which climate extremes may act on the carbon cycle. We find that ecosystem responses can exceed the duration of the climate impacts via lagged effects on the carbon cycle. The expected regional impacts of future climate extremes will depend on changes in the probability and severity of their occurrence, on the compound effects and timing of different climate extremes, and on the vulnerability of each land-cover type modulated by management. Although processes and sensitivities differ among biomes, based on expert opinion, we expect forests to exhibit the largest net effect of extremes due to their large carbon pools and fluxes, potentially large indirect and lagged impacts, and long recovery time to regain previous stocks. At the global scale, we presume that droughts have the strongest and most widespread effects on terrestrial carbon cycling. Comparing impacts of climate extremes identified via remote sensing vs. ground-based observational case studies reveals that many regions in the (sub-)tropics are understudied. Hence, regional investigations are needed to allow a global upscaling of the impacts of climate extremes on global carbon-climate feedbacks.
KW  - carbon cycle
KW  - climate change
KW  - climate extremes
KW  - climate variability
KW  - disturbance
KW  - terrestrial ecosystems
Y1  - 2015
U6  - https://doi.org/10.1111/gcb.12916
SN  - 1354-1013
SN  - 1365-2486
VL  - 21
IS  - 8
SP  - 2861
EP  - 2880
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Young, Linda
A1  - Ueda, Kiyoshi
A1  - Gühr, Markus
A1  - Bucksbaum, Philip H.
A1  - Simon, Marc
A1  - Mukamel, Shaul
A1  - Rohringer, Nina
A1  - Prince, Kevin C.
A1  - Masciovecchio, Claudio
A1  - Meyer, Michael
A1  - Rudenko, Artem
A1  - Rolles, Daniel
A1  - Bostedt, Christoph
A1  - Fuchs, Matthias
A1  - Reis, David A.
A1  - Santra, Robin
A1  - Kapteyn, Henry
A1  - Murnane, Margaret
A1  - Ibrahim, Heide
A1  - Légaré, François
A1  - Vrakking, Marc
A1  - Isinger, Marcus
A1  - Kroon, David
A1  - Gisselbrecht, Mathieu
A1  - L'Huillier, Anne
A1  - Wörner, Hans Jakob
A1  - Leone, Stephen R.
T1  - Roadmap of ultrafast x-ray atomic and molecular physics
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - X-ray free-electron lasers (XFELs) and table-top sources of x-rays based upon high harmonic generation (HHG) have revolutionized the field of ultrafast x-ray atomic and molecular physics, largely due to an explosive growth in capabilities in the past decade. XFELs now provide unprecedented intensity (1020 W cm−2) of x-rays at wavelengths down to ~1 Ångstrom, and HHG provides unprecedented time resolution (~50 attoseconds) and a correspondingly large coherent bandwidth at longer wavelengths. For context, timescales can be referenced to the Bohr orbital period in hydrogen atom of 150 attoseconds and the hydrogen-molecule vibrational period of 8 femtoseconds; wavelength scales can be referenced to the chemically significant carbon K-edge at a photon energy of ~280 eV (44 Ångstroms) and the bond length in methane of ~1 Ångstrom. With these modern x-ray sources one now has the ability to focus on individual atoms, even when embedded in a complex molecule, and view electronic and nuclear motion on their intrinsic scales (attoseconds and Ångstroms). These sources have enabled coherent diffractive imaging, where one can image non-crystalline objects in three dimensions on ultrafast timescales, potentially with atomic resolution. The unprecedented intensity available with XFELs has opened new fields of multiphoton and nonlinear x-ray physics where behavior of matter under extreme conditions can be explored. The unprecedented time resolution and pulse synchronization provided by HHG sources has kindled fundamental investigations of time delays in photoionization, charge migration in molecules, and dynamics near conical intersections that are foundational to AMO physics and chemistry. This roadmap coincides with the year when three new XFEL facilities, operating at Ångstrom wavelengths, opened for users (European XFEL, Swiss-FEL and PAL-FEL in Korea) almost doubling the present worldwide number of XFELs, and documents the remarkable progress in HHG capabilities since its discovery roughly 30 years ago, showcasing experiments in AMO physics and other applications. Here we capture the perspectives of 17 leading groups and organize the contributions into four categories: ultrafast molecular dynamics, multidimensional x-ray spectroscopies; high-intensity x-ray phenomena; attosecond x-ray science.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 668 
KW  - ultrafast molecular dynamics
KW  - x-ray spectroscopies and phenomena
KW  - table-top sources
KW  - x-ray free-electron lasers
KW  - attosecond phenomena
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-424238
SN  - 1866-8372
IS  - 668
ER  - 
TY  - JOUR
A1  - Anders, Jakob
A1  - Mefenza, Michael
A1  - Bobda, Christophe
A1  - Yonga, Franck
A1  - Aklah, Zeyad
A1  - Gunn, Kevin
T1  - A hardware/software prototyping system for driving assistance investigations
JF  - Journal of real-time image processing
N2  - A holistic design and verification environment to investigate driving assistance systems is presented, with an emphasis on system-on-chip architectures for video applications. Starting with an executable specification of a driving assistance application, subsequent transformations are performed across different levels of abstraction until the final implementation is achieved. The hardware/software partitioning is facilitated through the integration of OpenCV and SystemC in the same design environment, as well as OpenCV and Linux in the run-time system. We built a rapid prototyping, FPGA-based camera system, which allows designs to be explored and evaluated in realistic conditions. Using lane departure and the corresponding performance speedup, we show that our platform reduces the design time, while improving the verification efforts.
KW  - System on chip
KW  - Prototyping
KW  - Hardware/software system
KW  - Image processing
KW  - Design flow
KW  - Driver assistance
KW  - FPGA
KW  - Hardware acceleration
Y1  - 2016
U6  - https://doi.org/10.1007/s11554-013-0351-4
SN  - 1861-8200
SN  - 1861-8219
VL  - 11
SP  - 559
EP  - 569
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Kamjunke, Norbert
A1  - Rode, Michael
A1  - Baborowski, Martina
A1  - Kunz, Julia Vanessa
A1  - Zehner, Jakob
A1  - Borchardt, Dietrich
A1  - Weitere, Markus
T1  - High irradiation and low discharge promote the dominant role of phytoplankton in riverine nutrient dynamics
JF  - Limnology and oceanography / American Society of Limnology and Oceanography
N2  - Rivers play a relevant role in the nutrient turnover during the transport from land to ocean. Here, highly dynamic planktonic processes are more important compared to streams making it necessary to link the dynamics of nutrient turnover to control mechanisms of phytoplankton. We investigated the basic conditions leading to high phytoplankton biomass and corresponding nutrient dynamics in eutrophic, 8th order River Elbe (Germany). In a first step, we performed six Lagrangian sampling campaigns in the lower river section at different hydrological conditions. While nutrient concentrations remained high at low algal densities in autumn and at moderate discharge in summer, high algal concentrations occurred at low discharge in summer. Under these conditions, concentrations of silica and nitrate decreased and rates of nitrate assimilation were high. Soluble reactive phosphorus was depleted and particulate phosphorus increased inversely. Rising molar C:P ratios of seston indicated a phosphorus limitation of phytoplankton, so far rarely observed in eutrophic large rivers. Global radiation combined with mixing depth had a strong predictive power to explain maximum chlorophyll concentration. In a second step, we estimated nutrient turnover exemplarily for N during the campaign with the lowest discharge based on mass balances and metabolism-based process measurements. Mass balance calculations revealed a total nitrate uptake of 423 mg N m(-2)d(-1). Increasing phytoplankton density dominantly explained whole river gross primary production and related assimilatory nutrient uptake. In conclusion, riverine nutrient uptake strongly depends on the growth conditions for phytoplankton, which are favored at high irradiation and low discharge.
Y1  - 2021
U6  - https://doi.org/10.1002/lno.11778
SN  - 0024-3590
SN  - 1939-5590
VL  - 66
IS  - 7
SP  - 2648
EP  - 2660
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Dorband, Ira Irina
A1  - Jakob, Michael
A1  - Kalkuhl, Matthias
A1  - Steckel, Jan Christoph
T1  - Poverty and distributional effects of carbon pricing in low- and middle- income countries
BT  - a global comparative analysis
T2  - Postprints der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe
N2  - Even though concerns about adverse distributional implications for the poor are one of the most important political challenges for carbon pricing, the existing literature reveals ambiguous results. For this reason, we assess the expected incidence of moderate carbon price increases for different income groups in 87 mostly low- and middle-income countries. Building on a consistent dataset and method, we find that for countries with per capita incomes of below USD 15,000 per year (at PPP-adjusted 2011 USD) carbon pricing has, on average, progressive distributional effects. We also develop a novel decomposition technique to show that distributional outcomes are primarily determined by differences among income groups in consumption patterns of energy, rather than of food, goods or services. We argue that an inverse U-shape relationship between energy expenditure shares and income explains why carbon pricing tends to be regressive in countries with relatively higher income. Since these countries are likely to have more financial resources and institutional capacities to deal with distributional issues, our findings suggest that mitigating climate change, raising domestic revenue and reducing economic inequality are not mutually exclusive, even in low- and middle-income countries.
T3  - Zweitveröffentlichungen der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe - 103 
KW  - carbon pricing
KW  - distributional effect
KW  - decomposition analysis
KW  - global comparison
KW  - household data
KW  - low- and middle-income countries
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-424592
SN  - 1867-5808
IS  - 103
ER  - 
TY  - JOUR
A1  - Dorband, Ira Irina
A1  - Jakob, Michael
A1  - Kalkuhl, Matthias
A1  - Steckel, Jan Christoph
T1  - Poverty and distributional effects of carbon pricing in low- and middle-income countries - A global comparative analysis
JF  - World development
N2  - Even though concerns about adverse distributional implications for the poor are one of the most important political challenges for carbon pricing, the existing literature reveals ambiguous results. For this reason, we assess the expected incidence of moderate carbon price increases for different income groups in 87 mostly low- and middle-income countries. Building on a consistent dataset and method, we find that for countries with per capita incomes of below USD 15,000 per year (at PPP-adjusted 2011 USD) carbon pricing has, on average, progressive distributional effects. We also develop a novel decomposition technique to show that distributional outcomes are primarily determined by differences among income groups in consumption patterns of energy, rather than of food, goods or services. We argue that an inverse U-shape relationship between energy expenditure shares and income explains why carbon pricing tends to be regressive in countries with relatively higher income. Since these countries are likely to have more financial resources and institutional capacities to deal with distributional issues, our findings suggest that mitigating climate change, raising domestic revenue and reducing economic inequality are not mutually exclusive, even in low- and middle-income countries. (C) 2018 The Authors. Published by Elsevier Ltd.
KW  - Carbon pricing
KW  - Distributional effect
KW  - Decomposition analysis
KW  - Global comparison
KW  - Household data
KW  - Low- and middle-income countries
Y1  - 2019
U6  - https://doi.org/10.1016/j.worlddev.2018.11.015
SN  - 0305-750X
VL  - 115
SP  - 246
EP  - 257
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - GEN
A1  - Kalkuhl, Matthias
A1  - Steckel, Jan Christoph
A1  - Montrone, Lorenzo
A1  - Jakob, Michael
A1  - Peters, Jörg
A1  - Edenhofer, Ottmar
T1  - Successful coal phase-out requires new models of development
T2  - Nature Energy
N2  - Different energy sources have different spillovers on economic development and industrialization. Pathways of economic development based on renewable energy sources might require additional policies to support industrial development.
Y1  - 2019
U6  - https://doi.org/10.1038/s41560-019-0500-5
SN  - 2058-7546
VL  - 4
IS  - 11
SP  - 897
EP  - 900
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Gronke, Konrad
A1  - Hernandez, Pedro P.
A1  - Zimmermann, Jakob
A1  - Klose, Christoph S. N.
A1  - Kofoed-Branzk, Michael
A1  - Guendel, Fabian
A1  - Witkowski, Mario
A1  - Tizian, Caroline
A1  - Amann, Lukas
A1  - Schumacher, Fabian
A1  - Glatt, Hansruedi
A1  - Triantafyllopoulou, Antigoni
A1  - Diefenbach, Andreas
T1  - Interleukin-22 protects intestinal stem cells against genotoxic stress
JF  - Nature : the international weekly journal of science
N2  - Environmental genotoxic factors pose a challenge to the genomic integrity of epithelial cells at barrier surfaces that separate host organisms from the environment. They can induce mutations that, if they occur in epithelial stem cells, contribute to malignant transformation and cancer development1,2,3. Genome integrity in epithelial stem cells is maintained by an evolutionarily conserved cellular response pathway, the DNA damage response (DDR). The DDR culminates in either transient cell-cycle arrest and DNA repair or elimination of damaged cells by apoptosis4,5. Here we show that the cytokine interleukin-22 (IL-22), produced by group 3 innate lymphoid cells (ILC3) and γδ T cells, is an important regulator of the DDR machinery in intestinal epithelial stem cells. Using a new mouse model that enables sporadic inactivation of the IL-22 receptor in colon epithelial stem cells, we demonstrate that IL-22 is required for effective initiation of the DDR following DNA damage. Stem cells deprived of IL-22 signals and exposed to carcinogens escaped DDR-controlled apoptosis, contained more mutations and were more likely to give rise to colon cancer. We identified metabolites of glucosinolates, a group of phytochemicals contained in cruciferous vegetables, to be a widespread source of genotoxic stress in intestinal epithelial cells. These metabolites are ligands of the aryl hydrocarbon receptor (AhR)6, and AhR-mediated signalling in ILC3 and γδ T cells controlled their production of IL-22. Mice fed with diets depleted of glucosinolates produced only very low levels of IL-22 and, consequently, the DDR in epithelial cells of mice on a glucosinolate-free diet was impaired. This work identifies a homeostatic network protecting stem cells against challenge to their genome integrity by AhR-mediated ‘sensing’ of genotoxic compounds from the diet. AhR signalling, in turn, ensures on-demand production of IL-22 by innate lymphocytes directly regulating components of the DDR in epithelial stem cells.
Y1  - 2019
U6  - https://doi.org/10.1038/s41586-019-0899-7
SN  - 0028-0836
SN  - 1476-4687
VL  - 566
IS  - 7743
SP  - 249
EP  - 253
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Saritoprak, Zeki
A1  - Vorpahl, Daniel
A1  - Turan, Hakan
A1  - Arslan, Hakki
A1  - Zoref, Arye
A1  - Tarabieh, Abdallah
A1  - Yeshaya, Joachim
A1  - Anzi, Menashe
A1  - Merkur, Lianne
A1  - Schmidt, Daniela
A1  - Schuster, Dirk
A1  - Langer, Armin
A1  - Blum, Rahel
A1  - Stürmann, Jakob
A1  - Pohlmann, Julia
A1  - Schulz, Michael Karl
A1  - Arnold, Rafael D.
A1  - Salzer, Dorothea M.
A1  - Geißler-Grünberg, Anke
A1  - Talabardon, Susanne
A1  - Rasumny, Wiebke
A1  - Stellmacher, Martha
A1  - Denz, Rebekka
A1  - Walter, Simon
A1  - Grözinger, Elvira
ED  - Riemer, Nathanael
ED  - Sanci, Kadir
ED  - Schulz, Michael Karl
T1  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien = Muslimisch-Jüdischer Dialog
T1  - PaRDeS : Journal of the Association of Jewish Studies = Muslim-Jewish Dialogue
T2  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V.
N2  - PaRDeS. Zeitschrift der Vereinigung für Jüdische Studien e.V., möchte die fruchtbare und facettenreiche Kultur des Judentums sowie seine Berührungspunkte zur Umwelt in den unterschiedlichen Bereichen dokumentieren. Daneben dient die Zeitschrift als Forum zur Positionierung der Fächer Jüdische Studien und Judaistik innerhalb des wissenschaftlichen Diskurses sowie zur Diskussion ihrer historischen und gesellschaftlichen Verantwortung.
N2  - The journal aims at documenting the fruitful and multifarious culture of Judaism as well as its relations to its environment within diverse areas of research. In addition, the journal is meant to promote Jewish Studies within academic discourse and discuss its historic and social responsibility.
T3  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. - 22 
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-95416
SN  - 978-3-86956-370-1
SN  - 1614-6492
SN  - 1862-7684
IS  - 22
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Kim, MyoungHwee
A1  - Lin, Chiao-I
A1  - Henschke, Jakob
A1  - Quarmby, Andrew James
A1  - Engel, Tilman
A1  - Cassel, Michael
T1  - Effects of exercise treatment on functional outcome parameters in mid-portion achilles tendinopathy
BT  - a systematic review
JF  - Frontiers in Sports and Active Living
N2  - Exercise interventions are evident in the treatment of mid-portion Achilles tendinopathy (AT). However, there is still a lack of knowledge concerning the effect of different exercise treatments on improving a specific function (e.g., strength) in this population. Thus, this study aimed to systematically review the effect of exercise treatments on different functional outcomes in mid-portion AT. An electronic database of Pubmed, Web of Science, and Cochrane Central Register of Controlled Trials were searched from inception to 21 February 2023. Studies that investigated changes in plantar flexor function with exercise treatments were considered in mid-portion AT. Only randomized controlled trials (RCTs) and clinical controlled trials (CCTs) were included. Functional outcomes were classified by kinetic (e.g., strength), kinematic [e.g., ankle range of motion (ROM)], and sensorimotor (e.g., balance index) parameters. The types of exercise treatments were classified into eccentric, concentric, and combined (eccentric plus concentric) training modes. Quality assessment was appraised using the Physiotherapy Evidence Database scale for RCTs, and the Joanna Briggs Institute scale for CCTs. The search yielded 2,260 records, and a total of ten studies were included. Due to the heterogeneity of the included studies, a qualitative synthesis was performed. Eccentric training led to improvements in power outcomes (e.g., height of countermovement jump), and in strength outcomes (e.g., peak torque). Concentric training regimens showed moderate enhanced power outcomes. Moreover, one high-quality study showed an improvement in the balance index by eccentric training, whereas the application of concentric training did not. Combined training modalities did not lead to improvements in strength and power outcomes. Plantarflexion and dorsiflexion ROM measures did not show relevant changes by the exercise treatments. In conclusion, eccentric training is evident in improving strength outcomes in AT patients. Moreover, it shows moderate evidence improvements in power and the sensorimotor parameter "balance index". Concentric training presents moderate evidence in the power outcomes and can therefore be considered as an alternative to improve this function. Kinematic analysis of plantarflexion and dorsiflexion ROM might not be useful in AT people. This study expands the knowledge what types of exercise regimes should be considered to improve the functional outcomes in AT.
KW  - exercise treatments
KW  - eccentric training
KW  - concentric training
KW  - combined training
KW  - kinetic parameters
KW  - kinematic parameters
KW  - sensorimotor parameters
KW  - mid-portion achilles tendinopathy
Y1  - 2023
U6  - https://doi.org/10.3389/fspor.2023.1144484
SN  - 2624-9367
VL  - 5
PB  - Frontiers Media
CY  - Lausanne
ER  - 
TY  - GEN
A1  - Quarmby, Andrew James
A1  - Mönnig, Jamal
A1  - Mugele, Hendrik
A1  - Henschke, Jakob
A1  - Kim, MyoungHwee
A1  - Cassel, Michael
A1  - Engel, Tilman
T1  - Biomechanics and lower limb function are altered in athletes and runners with achilles tendinopathy compared with healthy controls: A systematic review
T2  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - Achilles tendinopathy (AT) is a debilitating injury in athletes, especially for those engaged in repetitive stretch-shortening cycle activities. Clinical risk factors are numerous, but it has been suggested that altered biomechanics might be associated with AT. No systematic review has been conducted investigating these biomechanical alterations in specifically athletic populations. Therefore, the aim of this systematic review was to compare the lower-limb biomechanics of athletes with AT to athletically matched asymptomatic controls. Databases were searched for relevant studies investigating biomechanics during gait activities and other motor tasks such as hopping, isolated strength tasks, and reflex responses. Inclusion criteria for studies were an AT diagnosis in at least one group, cross-sectional or prospective data, at least one outcome comparing biomechanical data between an AT and healthy group, and athletic populations. Studies were excluded if patients had Achilles tendon rupture/surgery, participants reported injuries other than AT, and when only within-subject data was available.. Effect sizes (Cohen's d) with 95% confidence intervals were calculated for relevant outcomes. The initial search yielded 4,442 studies. After screening, twenty studies (775 total participants) were synthesised, reporting on a wide range of biomechanical outcomes. Females were under-represented and patients in the AT group were three years older on average. Biomechanical alterations were identified in some studies during running, hopping, jumping, strength tasks and reflex activity. Equally, several biomechanical variables studied were not associated with AT in included studies, indicating a conflicting picture. Kinematics in AT patients appeared to be altered in the lower limb, potentially indicating a pattern of “medial collapse”. Muscular activity of the calf and hips was different between groups, whereby AT patients exhibited greater calf electromyographic amplitudes despite lower plantar flexor strength. Overall, dynamic maximal strength of the plantar flexors, and isometric strength of the hips might be reduced in the AT group. This systematic review reports on several biomechanical alterations in athletes with AT. With further research, these factors could potentially form treatment targets for clinicians, although clinical approaches should take other contributing health factors into account. The studies included were of low quality, and currently no solid conclusions can be drawn.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 830 
KW  - achilles tendinopathy
KW  - biomechanics
KW  - neuromuscular
KW  - kinetics
KW  - electromyography
KW  - athletes
KW  - runners
KW  - kinematics
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-587603
SN  - 1866-8364
IS  - 830
ER  - 
TY  - JOUR
A1  - Quarmby, Andrew James
A1  - Mönnig, Jamal
A1  - Mugele, Hendrik
A1  - Henschke, Jakob
A1  - Kim, MyoungHwee
A1  - Cassel, Michael
A1  - Engel, Tilman
T1  - Biomechanics and lower limb function are altered in athletes and runners with achilles tendinopathy compared with healthy controls: A systematic review
JF  - Frontiers in Sports and Active Living
N2  - Achilles tendinopathy (AT) is a debilitating injury in athletes, especially for those engaged in repetitive stretch-shortening cycle activities. Clinical risk factors are numerous, but it has been suggested that altered biomechanics might be associated with AT. No systematic review has been conducted investigating these biomechanical alterations in specifically athletic populations. Therefore, the aim of this systematic review was to compare the lower-limb biomechanics of athletes with AT to athletically matched asymptomatic controls. Databases were searched for relevant studies investigating biomechanics during gait activities and other motor tasks such as hopping, isolated strength tasks, and reflex responses. Inclusion criteria for studies were an AT diagnosis in at least one group, cross-sectional or prospective data, at least one outcome comparing biomechanical data between an AT and healthy group, and athletic populations. Studies were excluded if patients had Achilles tendon rupture/surgery, participants reported injuries other than AT, and when only within-subject data was available.. Effect sizes (Cohen's d) with 95% confidence intervals were calculated for relevant outcomes. The initial search yielded 4,442 studies. After screening, twenty studies (775 total participants) were synthesised, reporting on a wide range of biomechanical outcomes. Females were under-represented and patients in the AT group were three years older on average. Biomechanical alterations were identified in some studies during running, hopping, jumping, strength tasks and reflex activity. Equally, several biomechanical variables studied were not associated with AT in included studies, indicating a conflicting picture. Kinematics in AT patients appeared to be altered in the lower limb, potentially indicating a pattern of “medial collapse”. Muscular activity of the calf and hips was different between groups, whereby AT patients exhibited greater calf electromyographic amplitudes despite lower plantar flexor strength. Overall, dynamic maximal strength of the plantar flexors, and isometric strength of the hips might be reduced in the AT group. This systematic review reports on several biomechanical alterations in athletes with AT. With further research, these factors could potentially form treatment targets for clinicians, although clinical approaches should take other contributing health factors into account. The studies included were of low quality, and currently no solid conclusions can be drawn.
KW  - achilles tendinopathy
KW  - biomechanics
KW  - neuromuscular
KW  - kinetics
KW  - electromyography
KW  - athletes
KW  - runners
KW  - kinematics
Y1  - 2023
U6  - https://doi.org/10.3389/fspor.2022.1012471
SN  - 2624-9367
PB  - Frontiers
CY  - Lausanne, Schweiz
ER  - 
TY  - GEN
A1  - Stolterfoht, Martin
A1  - Grischek, Max
A1  - Caprioglio, Pietro
A1  - Wolff, Christian Michael
A1  - Gutierrez-Partida, Emilio
A1  - Peña-Camargo, Francisco
A1  - Rothhardt, Daniel
A1  - Zhang, Shanshan
A1  - Raoufi, Meysam
A1  - Wolansky, Jakob
A1  - Abdi-Jalebi, Mojtaba
A1  - Stranks, Samuel D.
A1  - Albrecht, Steve
A1  - Kirchartz, Thomas
A1  - Neher, Dieter
T1  - How to quantify the efficiency potential of neat perovskite films
BT  - Perovskite semiconductors with an implied efficiency exceeding 28%
T2  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Perovskite photovoltaic (PV) cells have demonstrated power conversion efficiencies (PCE) that are close to those of monocrystalline silicon cells; however, in contrast to silicon PV, perovskites are not limited by Auger recombination under 1-sun illumination. Nevertheless, compared to GaAs and monocrystalline silicon PV, perovskite cells have significantly lower fill factors due to a combination of resistive and non-radiative recombination losses. This necessitates a deeper understanding of the underlying loss mechanisms and in particular the ideality factor of the cell. By measuring the intensity dependence of the external open-circuit voltage and the internal quasi-Fermi level splitting (QFLS), the transport resistance-free efficiency of the complete cell as well as the efficiency potential of any neat perovskite film with or without attached transport layers are quantified. Moreover, intensity-dependent QFLS measurements on different perovskite compositions allows for disentangling of the impact of the interfaces and the perovskite surface on the non-radiative fill factor and open-circuit voltage loss. It is found that potassium-passivated triple cation perovskite films stand out by their exceptionally high implied PCEs > 28%, which could be achieved with ideal transport layers. Finally, strategies are presented to reduce both the ideality factor and transport losses to push the efficiency to the thermodynamic limit.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1434 
KW  - non-radiative interface recombination
KW  - perovskite solar cells
KW  - photoluminescence
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-516622
SN  - 1866-8372
IS  - 17
ER  - 
TY  - JOUR
A1  - Stolterfoht, Martin
A1  - Grischek, Max
A1  - Caprioglio, Pietro
A1  - Wolff, Christian Michael
A1  - Gutierrez-Partida, Emilio
A1  - Peña-Camargo, Francisco
A1  - Rothhardt, Daniel
A1  - Zhang, Shanshan
A1  - Raoufi, Meysam
A1  - Wolansky, Jakob
A1  - Abdi-Jalebi, Mojtaba
A1  - Stranks, Samuel D.
A1  - Albrecht, Steve
A1  - Kirchartz, Thomas
A1  - Neher, Dieter
T1  - How to quantify the efficiency potential of neat perovskite films
BT  - Perovskite semiconductors with an implied efficiency exceeding 28%
JF  - Advanced Materials
N2  - Perovskite photovoltaic (PV) cells have demonstrated power conversion efficiencies (PCE) that are close to those of monocrystalline silicon cells; however, in contrast to silicon PV, perovskites are not limited by Auger recombination under 1-sun illumination. Nevertheless, compared to GaAs and monocrystalline silicon PV, perovskite cells have significantly lower fill factors due to a combination of resistive and non-radiative recombination losses. This necessitates a deeper understanding of the underlying loss mechanisms and in particular the ideality factor of the cell. By measuring the intensity dependence of the external open-circuit voltage and the internal quasi-Fermi level splitting (QFLS), the transport resistance-free efficiency of the complete cell as well as the efficiency potential of any neat perovskite film with or without attached transport layers are quantified. Moreover, intensity-dependent QFLS measurements on different perovskite compositions allows for disentangling of the impact of the interfaces and the perovskite surface on the non-radiative fill factor and open-circuit voltage loss. It is found that potassium-passivated triple cation perovskite films stand out by their exceptionally high implied PCEs > 28%, which could be achieved with ideal transport layers. Finally, strategies are presented to reduce both the ideality factor and transport losses to push the efficiency to the thermodynamic limit.
KW  - non-radiative interface recombination
KW  - perovskite solar cells
KW  - photoluminescence
Y1  - 2020
U6  - https://doi.org/10.1002/adma.202000080
SN  - 0935-9648
SN  - 1521-4095
VL  - 32
IS  - 17
SP  - 1
EP  - 10
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - GEN
A1  - Awasthi, Swapnil
A1  - Kaminski, Jakob
A1  - Rapp, Michael A.
A1  - Schlagenhauf, Florian
A1  - Walter, Henrik
A1  - Ruggeri, Barbara
A1  - Ripke, Stephan
A1  - Schumann, Gunter
A1  - Heinz, Andreas
T1  - A neural signature of malleability
BT  - general intelligence correlates with ventral striatal  activation and epigenetic makers of dopamine neurotransmission
T2  - European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
N2  - General intelligence has a substantial genetic background in children, adolescents, and adults, but environmental factors also strongly correlate with cognitive performance as evidenced by a strong (up to one SD) increase in average intelligence test results in the second half of the previous century. This change occurred in a period apparently too short to accommodate radical genetic changes. It is highly suggestive that environmental factors interact with genotype by possible modification of epigenetic factors that regulate gene expression and thus contribute to individual malleability. This modification might as well be reflected in recent observations of an association between dopamine-dependent encoding of reward prediction errors and cognitive capacity, which was modulated by adverse life events.
Y1  - 2019
U6  - https://doi.org/10.1016/j.euroneuro.2017.08.139
SN  - 0924-977X
SN  - 1873-7862
VL  - 29
SP  - S858
EP  - S859
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - van der Meij, Marijn W.
A1  - Reimann, Tony
A1  - Vornehm, V. K.
A1  - Temme, Arnaud J. A. M.
A1  - Wallinga, Jakob
A1  - van Beek, Roy
A1  - Sommer, Michael
T1  - Reconstructing rates and patterns of colluvial soil redistribution in agrarian (hummocky) landscapes
JF  - Earth surface processes and landforms : the journal of the British Geomorphological Research Group
N2  - Humans have triggered or accelerated erosion processes since prehistoric times through agricultural practices. Optically stimulated luminescence (OSL) is widely used to quantify phases and rates of the corresponding landscape change, by measuring the last moment of daylight exposure of sediments. However, natural and anthropogenic mixing processes, such as bioturbation and tillage, complicate the use of OSL as grains of different depositional ages become mixed, and grains become exposed to light even long after the depositional event of interest. Instead, OSL determines the stabilization age, indicating when sediments were buried below the active mixing zone. These stabilization ages can cause systematic underestimation when calculating deposition rates. Our focus is on colluvial deposition in a kettle hole in the Uckermark region, northeastern Germany. We took 32 samples from five locations in the colluvium filling the kettle hole to study both spatial and temporal patterns in colluviation. We combined OSL dating with advanced age modelling to determine the stabilization age of colluvial sediments. These ages were combined with an archaeological reconstruction of historical ploughing depths to derive the levels of the soil surface at the moment of stabilization; the deposition depths, which were then used to calculate unbiased deposition rates. We identified two phases of colluvial deposition. The oldest deposits (similar to 5 ka) were located at the fringe of the kettle hole and accumulated relatively slowly, whereas the youngest deposits (<0.3 ka) rapidly filled the central kettle hole with rates of two orders of magnitude higher. We suggest that the latter phase is related to artificial drainage, facilitating accessibility in the central depression for agricultural practices. Our results show the need for numerical dating techniques that take archaeological and soil-geomorphological information into account to identify spatiotemporal patterns of landscape change, and to correctly interpret landscape dynamics in anthropogenically influenced hilly landscapes. (c) 2019 The Authors. Earth Surface Processes and Landforms Published by John Wiley & Sons Ltd.
KW  - geochronology
KW  - OSL
KW  - tillage
KW  - erosion
KW  - kettle hole
KW  - hummocky
KW  - landscape evolution
Y1  - 2019
U6  - https://doi.org/10.1002/esp.4671
SN  - 0197-9337
SN  - 1096-9837
VL  - 44
IS  - 12
SP  - 2408
EP  - 2422
PB  - Wiley
CY  - Hoboken
ER  -