TY - CHAP A1 - Kurbel, Karl A1 - Nowak, Dawid A1 - Azodi, Amir A1 - Jaeger, David A1 - Meinel, Christoph A1 - Cheng, Feng A1 - Sapegin, Andrey A1 - Gawron, Marian A1 - Morelli, Frank A1 - Stahl, Lukas A1 - Kerl, Stefan A1 - Janz, Mariska A1 - Hadaya, Abdulmasih A1 - Ivanov, Ivaylo A1 - Wiese, Lena A1 - Neves, Mariana A1 - Schapranow, Matthieu-Patrick A1 - Fähnrich, Cindy A1 - Feinbube, Frank A1 - Eberhardt, Felix A1 - Hagen, Wieland A1 - Plauth, Max A1 - Herscheid, Lena A1 - Polze, Andreas A1 - Barkowsky, Matthias A1 - Dinger, Henriette A1 - Faber, Lukas A1 - Montenegro, Felix A1 - Czachórski, Tadeusz A1 - Nycz, Monika A1 - Nycz, Tomasz A1 - Baader, Galina A1 - Besner, Veronika A1 - Hecht, Sonja A1 - Schermann, Michael A1 - Krcmar, Helmut A1 - Wiradarma, Timur Pratama A1 - Hentschel, Christian A1 - Sack, Harald A1 - Abramowicz, Witold A1 - Sokolowska, Wioletta A1 - Hossa, Tymoteusz A1 - Opalka, Jakub A1 - Fabisz, Karol A1 - Kubaczyk, Mateusz A1 - Cmil, Milena A1 - Meng, Tianhui A1 - Dadashnia, Sharam A1 - Niesen, Tim A1 - Fettke, Peter A1 - Loos, Peter A1 - Perscheid, Cindy A1 - Schwarz, Christian A1 - Schmidt, Christopher A1 - Scholz, Matthias A1 - Bock, Nikolai A1 - Piller, Gunther A1 - Böhm, Klaus A1 - Norkus, Oliver A1 - Clark, Brian A1 - Friedrich, Björn A1 - Izadpanah, Babak A1 - Merkel, Florian A1 - Schweer, Ilias A1 - Zimak, Alexander A1 - Sauer, Jürgen A1 - Fabian, Benjamin A1 - Tilch, Georg A1 - Müller, David A1 - Plöger, Sabrina A1 - Friedrich, Christoph M. A1 - Engels, Christoph A1 - Amirkhanyan, Aragats A1 - van der Walt, Estée A1 - Eloff, J. H. P. A1 - Scheuermann, Bernd A1 - Weinknecht, Elisa ED - Meinel, Christoph ED - Polze, Andreas ED - Oswald, Gerhard ED - Strotmann, Rolf ED - Seibold, Ulrich ED - Schulzki, Bernhard T1 - HPI Future SOC Lab BT - Proceedings 2015 N2 - Das Future SOC Lab am HPI ist eine Kooperation des Hasso-Plattner-Instituts mit verschiedenen Industriepartnern. Seine Aufgabe ist die Ermöglichung und Förderung des Austausches zwischen Forschungsgemeinschaft und Industrie. Am Lab wird interessierten Wissenschaftlern eine Infrastruktur von neuester Hard- und Software kostenfrei für Forschungszwecke zur Verfügung gestellt. Dazu zählen teilweise noch nicht am Markt verfügbare Technologien, die im normalen Hochschulbereich in der Regel nicht zu finanzieren wären, bspw. Server mit bis zu 64 Cores und 2 TB Hauptspeicher. Diese Angebote richten sich insbesondere an Wissenschaftler in den Gebieten Informatik und Wirtschaftsinformatik. Einige der Schwerpunkte sind Cloud Computing, Parallelisierung und In-Memory Technologien. In diesem Technischen Bericht werden die Ergebnisse der Forschungsprojekte des Jahres 2015 vorgestellt. Ausgewählte Projekte stellten ihre Ergebnisse am 15. April 2015 und 4. November 2015 im Rahmen der Future SOC Lab Tag Veranstaltungen vor. KW - Future SOC Lab KW - Forschungsprojekte KW - Multicore Architekturen KW - In-Memory Technologie KW - Cloud Computing KW - maschinelles Lernen KW - künstliche Intelligenz Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-102516 ER - TY - JOUR A1 - Holdt, Hans-Jürgen A1 - Müller, Holger A1 - Potter, Matthias A1 - Kelling, Alexandra A1 - Schilde, Uwe A1 - Starke, Ines A1 - Heydenreich, Matthias A1 - Kleinpeter, Erich T1 - The first sandwich complex with an octa(thioether) coordination sphere : Bis(maleonitrile-tetrathia-12-crown- 4)silver(I) N2 - The new tetrathiacrown ethers maleonitrile-tetrathia-12-crown-4 (mn12S(4)) and maleonitrile-tetrathia-13-crown- 4 (mn13S(4)) have been prepared and characterised by X-ray crystallographic analysis. These crown ethers form 2:1, 3:2 and 1: 1 complexes with AgY (Y = BF4, PF6). The crystal structures of [Ag(mn12S(4))(2)]BF4 (3a), [Ag(mn13S(4))(2)]BF4 (4a) and [Ag-2(mn13S(4))(3)](PF6)(2) (6b) have been determined. Compound 3a contains the centrosymmetric sandwich complex cation [Ag(mn12S(4))(2)](+) where each mn12S(4) ligand is coordinated to the Ag centre in an endo manner through all four S atoms. The 2:1 complex [Ag(mn12S(4))(2)](+) is the first sandwich complex with a tetrathiacrown ether and the first complex with an octa(thioether) coordination sphere. The crystal structure of compound 4a also reveals a 2:1 complex. This complex, [Ag(mnl3S(4))(2)](+), exhibits a half-sandwich structure. One mn13S(4) ligand coordinates to Ag+ by all four S donor atoms and the other 13S(4) crown by only one S atom. Compound 6b contains a dinuclear Ag complex. The Ag complexes 3a,b-8a,b were also studied by electrospray ionisation mass spectrometry. Collision-induced dissociation (CID) was used to compare the relative stability of 2:1 complexes [AgL2]+ and 1:1 complexes [AgL](+) (L = mn12S(4), mn13S(4)). The C-13 NMR chemical shifts of 2:1 and 1:1 Ag complexes and their corresponding free ligands were also estimated and compared. The free energy of the barrier of ring inversion (Delta G(double dagger)) for [Ag(mn12S(4))(2)](+) was determined to be 64 kJmol(-1). Y1 - 2006 UR - http://www3.interscience.wiley.com/cgi-bin/jhome/27721/ U6 - https://doi.org/10.1002/ejic.200501109 SN - 1434-1948 ER - TY - JOUR A1 - Moustakas, Aristides A1 - Günther, Matthias A1 - Wiegand, Kerstin A1 - Müller, Karl-Heinz A1 - Ward, David A1 - Meyer, Katrin M. A1 - Jeltsch, Florian T1 - Long-term mortality patterns of the deep-rooted Acacia erioloba BT - The middle class shall die! JF - Journal of vegetation science N2 - Question: Is there a relationship between size and death in the Iona-lived, deep-rooted tree, Acacia erioloba, in a semi-arid savanna? What is the size-class distribution of A. erioloba mortality? Does the mortality distribution differ from total tree size distribution? Does A. erioloba mortality distribution match the mortality distributions recorded thus far in other environments? Location: Dronfield Ranch, near Kimberley, Kalahari, South Africa. Methods: A combination of aerial photographs and a satellite image covering 61 year was used to provide long-term spatial data on mortality. We used aerial photographs of the study area from 1940, 1964, 1984, 1993 and a satellite image from 2001 to follow three plots covering 510 ha. We were able to identify and individually follow ca. 3000 individual trees from 1940 till 2001. Results: The total number of trees increased over time. No relationship between total number of trees and mean tree size was detected. There were no trends over time in total number of deaths per plot or in size distributions of dead trees. Kolmogorov-Smirnov tests showed no differences in size class distributions for living trees through time. The size distribution of dead trees was significantly different from the size distribution of all trees present on the plots. Overall, the number of dead trees was low in small size classes, reached a peak value when canopy area was 20 - 30 m(2), and declined in lamer size-classes. Mortality as a ratio of dead vs. total trees peaked at intermediate canopy sizes too. Conclusion: A. erioloba mortality was size-dependent, peaking at intermediate sizes. The mortality distribution differs from all other tree mortality distributions recorded thus far. We suggest that a possible mechanism for this unusual mortality distribution is intraspecific competition for water in this semi-arid environment. KW - competition KW - long-term data KW - remote sensing KW - savanna KW - size dependent mortality KW - size distribution KW - tree death Y1 - 2006 U6 - https://doi.org/10.1111/j.1654-1103.2006.tb02468.x SN - 1100-9233 VL - 17 SP - 473 EP - 480 PB - Blackwell CY - Malden ER - TY - CHAP A1 - Curzon, Paul A1 - Kalas, Ivan A1 - Schubert, Sigrid A1 - Schaper, Niclas A1 - Barnes, Jan A1 - Kennewell, Steve A1 - Bröker, Kathrin A1 - Kastens, Uwe A1 - Magenheim, Johannes A1 - Dagiene, Valentina A1 - Stupuriene, Gabriele A1 - Ellis, Jason Brent A1 - Abreu-Ellis, Carla Reis A1 - Grillenberger, Andreas A1 - Romeike, Ralf A1 - Haugsbakken, Halvdan A1 - Jones, Anthony A1 - Lewin, Cathy A1 - McNicol, Sarah A1 - Nelles, Wolfgang A1 - Neugebauer, Jonas A1 - Ohrndorf, Laura A1 - Schaper, Niclas A1 - Schubert, Sigrid A1 - Opel, Simone A1 - Kramer, Matthias A1 - Trommen, Michael A1 - Pottbäcker, Florian A1 - Ilaghef, Youssef A1 - Passig, David A1 - Tzuriel, David A1 - Kedmi, Ganit Eshel A1 - Saito, Toshinori A1 - Webb, Mary A1 - Weigend, Michael A1 - Bottino, Rosa A1 - Chioccariello, Augusto A1 - Christensen, Rhonda A1 - Knezek, Gerald A1 - Gioko, Anthony Maina A1 - Angondi, Enos Kiforo A1 - Waga, Rosemary A1 - Ohrndorf, Laura A1 - Or-Bach, Rachel A1 - Preston, Christina A1 - Younie, Sarah A1 - Przybylla, Mareen A1 - Romeike, Ralf A1 - Reynolds, Nicholas A1 - Swainston, Andrew A1 - Bendrups, Faye A1 - Sysło, Maciej M. A1 - Kwiatkowska, Anna Beata A1 - Zieris, Holger A1 - Gerstberger, Herbert A1 - Müller, Wolfgang A1 - Büchner, Steffen A1 - Opel, Simone A1 - Schiller, Thomas A1 - Wegner, Christian A1 - Zender, Raphael A1 - Lucke, Ulrike A1 - Diethelm, Ira A1 - Syrbe, Jörn A1 - Lai, Kwok-Wing A1 - Davis, Niki A1 - Eickelmann, Birgit A1 - Erstad, Ola A1 - Fisser, Petra A1 - Gibson, David A1 - Khaddage, Ferial A1 - Knezek, Gerald A1 - Micheuz, Peter A1 - Kloos, Carlos Delgado ED - Brinda, Torsten ED - Reynolds, Nicholas ED - Romeike, Ralf ED - Schwill, Andreas T1 - KEYCIT 2014 BT - key competencies in informatics and ICT N2 - In our rapidly changing world it is increasingly important not only to be an expert in a chosen field of study but also to be able to respond to developments, master new approaches to solving problems, and fulfil changing requirements in the modern world and in the job market. In response to these needs key competencies in understanding, developing and using new digital technologies are being brought into focus in school and university programmes. The IFIP TC3 conference "KEYCIT – Key Competences in Informatics and ICT (KEYCIT 2014)" was held at the University of Potsdam in Germany from July 1st to 4th, 2014 and addressed the combination of key competencies, Informatics and ICT in detail. The conference was organized into strands focusing on secondary education, university education and teacher education (organized by IFIP WGs 3.1 and 3.3) and provided a forum to present and to discuss research, case studies, positions, and national perspectives in this field. T3 - Commentarii informaticae didacticae (CID) - 7 KW - Schlüsselkompetenzen KW - Informatik KW - Bildung KW - ICT KW - Informatikdidaktik KW - Key Competencies KW - Informatics KW - education KW - ICT KW - Computer Science Education Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-70325 SN - 978-3-86956-292-6 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Vogel, Heike A1 - Kamitz, Anne A1 - Hallahan, Nicole A1 - Lebek, Sandra A1 - Schallschmidt, Tanja A1 - Jonas, Wenke A1 - Jähnert, Markus A1 - Gottmann, Pascal A1 - Zellner, Lisa A1 - Kanzleiter, Timo A1 - Damen, Mareike A1 - Altenhofen, Delsi A1 - Burkhardt, Ralph A1 - Renner, Simone A1 - Dahlhoff, Maik A1 - Wolf, Eckhard A1 - Müller, Timo Dirk A1 - Blüher, Matthias A1 - Joost, Hans-Georg A1 - Chadt, Alexandra A1 - Al-Hasani, Hadi A1 - Schürmann, Annette T1 - A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes JF - Human molecular genetics N2 - To explore the genetic determinants of obesity and Type 2 diabetes (T2D), the German Center for Diabetes Research (DZD) conducted crossbreedings of the obese and diabetes-prone New Zealand Obese mouse strain with four different lean strains (B6, DBA, C3H, 129P2) that vary in their susceptibility to develop T2D. Genome-wide linkage analyses localized more than 290 quantitative trait loci (QTL) for obesity, 190 QTL for diabetes-related traits and 100 QTL for plasma metabolites in the out-cross populations. A computational framework was developed that allowed to refine critical regions and to nominate a small number of candidate genes by integrating reciprocal haplotype mapping and transcriptome data. The efficiency of the complex procedure was demonstrated for one obesity QTL. The genomic interval of 35 Mb with 502 annotated candidate genes was narrowed down to six candidates. Accordingly, congenic mice retained the obesity phenotype owing to an interval that contains three of the six candidate genes. Among these the phospholipase PLA2G4A exhibited an elevated expression in adipose tissue of obese human subjects and is therefore a critical regulator of the obesity locus. Together, our broad and complex approach demonstrates that combined- and comparative-cross analysis exhibits improved mapping resolution and represents a valid tool for the identification of disease genes. Y1 - 2018 U6 - https://doi.org/10.1093/hmg/ddy217 SN - 0964-6906 SN - 1460-2083 VL - 27 IS - 17 SP - 3099 EP - 3112 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Shenoy, Pradeep A1 - Krauledat, Matthias A1 - Blankertz, Benjamin A1 - Rao, Rajesh P. N. A1 - Müller, Klaus-Robert T1 - Towards adaptive classification for BCI N2 - Non-stationarities are ubiquitous in EEG signals. They are especially apparent in the use of EEG-based brain- computer interfaces (BCIs): (a) in the differences between the initial calibration measurement and the online operation of a BCI, or (b) caused by changes in the subject's brain processes during an experiment (e.g. due to fatigue, change of task involvement, etc). In this paper, we quantify for the first time such systematic evidence of statistical differences in data recorded during offline and online sessions. Furthermore, we propose novel techniques of investigating and visualizing data distributions, which are particularly useful for the analysis of (non-) stationarities. Our study shows that the brain signals used for control can change substantially from the offline calibration sessions to online control, and also within a single session. In addition to this general characterization of the signals, we propose several adaptive classification schemes and study their performance on data recorded during online experiments. An encouraging result of our study is that surprisingly simple adaptive methods in combination with an offline feature selection scheme can significantly increase BCI performance Y1 - 2006 UR - http://iopscience.iop.org/1741-2552/3/1/R02/ U6 - https://doi.org/10.1088/1741-2560/3/1/R02 ER - TY - JOUR A1 - Blankertz, Benjamin A1 - Dornhege, Guido A1 - Krauledat, Matthias A1 - Müller, Klaus-Robert A1 - Kunzmann, Volker A1 - Losch, Florian A1 - Curio, Gabriel T1 - The Berlin brain-computer interface : EEG-based communication without subject training N2 - The Berlin Brain-Computer Interface (BBCI) project develops a noninvasive BCI system whose key features are 1) the use of well-established motor competences as control paradigms, 2) high-dimensional features from 128-channel electroencephalogram (EEG), and 3) advanced machine learning techniques. As reported earlier, our experiments demonstrate that very high information transfer rates can be achieved using the readiness potential (RP) when predicting the laterality of upcoming left-versus right-hand movements in healthy subjects. A more recent study showed that the RP similarily accompanies phantom movements in arm amputees, but the signal strength decreases with longer loss of the limb. In a complementary approach, oscillatory features are used to discriminate imagined movements (left hand versus right hand versus foot). In a recent feedback study with six healthy subjects with no or very little experience with BCI control, three subjects achieved an information transfer rate above 35 bits per minute (bpm), and further two subjects above 24 and 15 bpm, while one subject could not achieve any BCI control. These results are encouraging for an EEG-based BCI system in untrained subjects that is independent of peripheral nervous system activity and does not rely on evoked potentials even when compared to results with very well-trained subjects operating other BCI systems Y1 - 2006 UR - http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=7333 U6 - https://doi.org/10.1109/Tnsre.2006.875557 SN - 1534-4320 ER - TY - CHAP A1 - Heinisch, Isabelle A1 - Romeike, Ralf A1 - Knobelsdorf, Maria A1 - Kreitz, Christoph A1 - Nylén, Aletta A1 - Dörge, Christina A1 - Göttel, Timo A1 - Holz, Jan A1 - Bergner, Nadine A1 - Schroeder, Ulrik A1 - Metzger, Christiane A1 - Haag, Johann A1 - Abke, Jörg A1 - Schwirtlich, Vincent A1 - Sedelmaier, Yvonne A1 - Müller, Dorothee A1 - Frommer, Andreas A1 - Humbert, Ludger A1 - Berges, Marc A1 - Mühling, Andreas A1 - Hubwieser, Peter A1 - Steuer, Horst A1 - Engbring, Dieter A1 - Selke, Harald A1 - Drews, Paul A1 - Schirmer, Ingrid A1 - Morisse, Marcel A1 - Sagawe, Arno A1 - Rolf, Arno A1 - Friedemann, Stefan A1 - Gröger, Stefan A1 - Schumann, Matthias A1 - Klinger, Melanie A1 - Polutina, Olena A1 - Bibel, Ariane A1 - Götz, Christian A1 - Brinda, Torsten A1 - Apel, Rebecca A1 - Berg, Tobias A1 - Bergner, Nadine A1 - Chatti, Mohamed Amine A1 - Leicht-Scholten, Carmen A1 - Schroeder, Ulrik A1 - Al-Saffar, Loay Talib A1 - Petre, Marian A1 - Schirmer, Ingrid A1 - Rick, Detlef ED - Forbrig, Peter ED - Rick, Detlef ED - Schmolitzky, Axel T1 - HDI 2012 – Informatik für eine nachhaltige Zukunft : 5. Fachtagung Hochschuldidaktik der Informatik ; 06.–07. November 2012, Universität Hamburg N2 - Die Tagungsreihe zur Hochschuldidaktik der Informatik HDI wird vom Fachbereich Informatik und Ausbildung / Didaktik der Informatik (IAD) in der Gesellschaft für Informatik e. V. (GI) organisiert. Sie dient den Lehrenden der Informatik in Studiengängen an Hochschulen als Forum der Information und des Austauschs über neue didaktische Ansätze und bildungspolitische Themen im Bereich der Hochschulausbildung aus der fachlichen Perspektive der Informatik. Diese fünfte HDI 2012 wurde an der Universität Hamburg organisiert. Für sie wurde das spezielle Motto „Informatik für eine nachhaltige Zukunft“ gewählt, um insbesondere Fragen der Bildungsrelevanz informatischer Inhalte, der Kompetenzen für Studierende informatisch geprägter Studiengänge und der Rolle der Informatik in der Hochschulentwicklung zu diskutieren. T3 - Commentarii informaticae didacticae (CID) - 5 Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-62891 SN - 978-3-86956-220-9 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - GEN A1 - Bringmann, Gerhard A1 - Mutanyatta-Comar, Joan A1 - Maksimenka, Katja A1 - Wanjohi, John M. A1 - Heydenreich, Matthias A1 - Brun, Reto A1 - Müller, Werner E. G. A1 - Peter, Martin A1 - Midiwo, Jacob O. A1 - Yenesew, Abiy T1 - Joziknipholones A and B : the First Dimeric Phenylanthraquinones, from the Roots of Bulbine frutescens N2 - From the roots of the African plant Bulbine frutescens (Asphodelaceae), two unprecedented novel dimeric phenylanthraquinones, named joziknipholones A and B, possessing axial and centrochirality, were isolated, together with six known compounds. Structural elucidation of the new metabolites was achieved by spectroscopic and chiroptical methods, by reductive cleavage of the central bond between the monomeric phenylanthraquinone and -anthrone portions with sodium dithionite, and by quantum chemical CD calculations. Based on the recently revised absolute axial configuration of the parent phenylanthraquinones, knipholone and knipholone anthrone, the new dimers were attributed to possess the P-configuration (i.e., with the acetyl portions below the anthraquinone plane) at both axes in the case of joziknipholone A, whereas in joziknipholone B, the knipholone part was found to be M-configured. Joziknipholones A and B are active against the chloroquine resistant strain K1 of the malaria pathogen, Plasmodium falciparum, and show moderate activity against murine leukemic lymphoma L5178y cells. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 104 KW - antimalarial activity KW - chirality KW - joziknipholones KW - natural products KW - structure elucidation Y1 - 2008 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-42638 ER - TY - JOUR A1 - Bringmann, Gerhard A1 - Mutanyatta-Comar, Joan A1 - Maksimenka, Katja A1 - Wanjohi, John M. A1 - Heydenreich, Matthias A1 - Brun, Reto A1 - Müller, Werner E. G. A1 - Peter, Martin G. A1 - Midiwo, Jacob O. A1 - Yenesew, Abiy T1 - Joziknipholones A and B : the first dimeric phenylanthraquinones, from the roots of Bulbine frutescens N2 - From the roots of the African plant Bulbine frutescens (Asphodelaceae), two unprecedented novel dimeric phenylanthraquinones, named joziknipholones A and B, possessing axial and centrochirality, were isolated, together with six known compounds. Structural elucidation of the new metabolites was achieved by spectroscopic and chiroptical methods, by reductive cleavage of the central bond between the monomeric phenylanthraquinone and -anthrone portions with sodium dithionite, and by quantum chemical CD calculations. Based on the recently revised absolute axial configuration of the parent phenylanthraquinones, knipholone and knipholone anthrone, the new dimers were attributed to possess the P- configuration (i.e., with the acetyl portions below the anthraquinone plane) at both axes in the case of joziknipholone A, whereas in joziknipholone B, the knipholone part was found to be M-configured. Joziknipholones A and B are active against the chloroquine resistant strain K1 of the malaria pathogen, Plasmodium falciparum, and show moderate activity against murine leukemic lymphoma L5178y cells. Y1 - 2008 UR - http://www3.interscience.wiley.com/journal/26293/home?CRETRY=1&SRETRY=0 SN - 0947-6539 ER - TY - JOUR A1 - Merks, Anne Margarete A1 - Swinarski, Marie A1 - Meyer, Alexander Matthias A1 - Müller, Nicola Victoria A1 - Özcan, Ismail A1 - Donat, Stefan A1 - Burger, Alexa A1 - Gilbert, Stephen A1 - Mosimann, Christian A1 - Abdelilah-Seyfried, Salim A1 - Panakova, Daniela T1 - Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity JF - Nature Communications N2 - Development of a multiple-chambered heart from the linear heart tube is inherently linked to cardiac looping. Although many molecular factors regulating the process of cardiac chamber ballooning have been identified, the cellular mechanisms underlying the chamber formation remain unclear. Here, we demonstrate that cardiac chambers remodel by cell neighbour exchange of cardiomyocytes guided by the planar cell polarity (PCP) pathway triggered by two non-canonical Wnt ligands, Wnt5b and Wnt11. We find that PCP signalling coordinates the localisation of actomyosin activity, and thus the efficiency of cell neighbour exchange. On a tissue-scale, PCP signalling planar-polarises tissue tension by restricting the actomyosin contractility to the apical membranes of outflow tract cells. The tissue-scale polarisation of actomyosin contractility is required for cardiac looping that occurs concurrently with chamber ballooning. Taken together, our data reveal that instructive PCP signals couple cardiac chamber expansion with cardiac looping through the organ-scale polarisation of actomyosin-based tissue tension. Y1 - 2018 U6 - https://doi.org/10.1038/s41467-018-04566-1 SN - 2041-1723 VL - 9 PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Träger, Juliane A1 - Klamroth, Tillmann A1 - Kelling, Alexandra A1 - Lubahn, Susanne A1 - Cleve, Ernst A1 - Mickler, Wulfhard A1 - Heydenreich, Matthias A1 - Müller, Holger A1 - Holdt, Hans-Jürgen T1 - Complexation of Palladium(II) with unsaturated Dithioethers a systematic development of highly selective ligands for solvent extraction JF - European journal of inorganic chemistry : a journal of ChemPubSoc Europe N2 - There is a demand for new and robust PdII extractants due to growing recycling rates. Chelating dithioethers are promising substances for solvent extraction as they form stable square-planar complexes with PdII. We have modified unsaturated dithioethers, which are known to coordinate PdII, and adapted them to the requirements of industrial practice. The ligands are analogues of 1,2-dithioethene with varying electron-withdrawing backbones and polar end-groups. The crystal structures of several ligands and their palladium complexes were determined as well as their electro- and photochemical properties, complex stability and behaviour in solution. Solvent extraction experiments showed the superiority of some of our ligands over conventionally used extractants in terms of their very fast reaction rates. With highly selective 1,2-bis(2-methoxyethylthio)benzene (4) it is possible to extract PdII from a highly acidic medium in the presence of other base and palladium-group metals. KW - Renewable resources KW - Palladium KW - Chelates KW - Ligand design KW - S li-gands Y1 - 2012 U6 - https://doi.org/10.1002/ejic.201101406 SN - 1434-1948 IS - 14 SP - 2341 EP - 2352 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Debatin, Franziska A1 - Thomas, Arne A1 - Kelling, Alexandra A1 - Hedin, Niklas A1 - Bacsik, Zoltan A1 - Senkovska, Irena A1 - Kaskel, Stefan A1 - Junginger, Matthias A1 - Müller, Holger A1 - Schilde, Uwe A1 - Jäger, Christian A1 - Friedrich, Alwin A1 - Holdt, Hans-Jürgen T1 - In situ synthesis of an imidazolate-4-amide-5-imidate ligand and formation of a microporous zinc-organic framework with H2-and CO2-storage ability N2 - Narrow channels with polar walls are the structural and functional features responsible for the high capacity of a zinc-organic framework based on an imidazolate-amide-imidate ligand for the uptake of H2 and CO2 (see structure: orange Zn, blue N, red O, dark gray C, light gray H). The rigid and stable chelating ligand was synthesized in situ by partial hydrolysis of a dicyanoimidazole compound. Y1 - 2010 UR - http://www3.interscience.wiley.com/cgi-bin/jhome/26737/ U6 - https://doi.org/10.1002/anie.200906188 SN - 1433-7851 ER - TY - JOUR A1 - Aarts, Alexander A. A1 - Anderson, Joanna E. A1 - Anderson, Christopher J. A1 - Attridge, Peter R. A1 - Attwood, Angela A1 - Axt, Jordan A1 - Babel, Molly A1 - Bahnik, Stepan A1 - Baranski, Erica A1 - Barnett-Cowan, Michael A1 - Bartmess, Elizabeth A1 - Beer, Jennifer A1 - Bell, Raoul A1 - Bentley, Heather A1 - Beyan, Leah A1 - Binion, Grace A1 - Borsboom, Denny A1 - Bosch, Annick A1 - Bosco, Frank A. A1 - Bowman, Sara D. A1 - Brandt, Mark J. A1 - Braswell, Erin A1 - Brohmer, Hilmar A1 - Brown, Benjamin T. A1 - Brown, Kristina A1 - Bruening, Jovita A1 - Calhoun-Sauls, Ann A1 - Callahan, Shannon P. A1 - Chagnon, Elizabeth A1 - Chandler, Jesse A1 - Chartier, Christopher R. A1 - Cheung, Felix A1 - Christopherson, Cody D. A1 - Cillessen, Linda A1 - Clay, Russ A1 - Cleary, Hayley A1 - Cloud, Mark D. A1 - Cohn, Michael A1 - Cohoon, Johanna A1 - Columbus, Simon A1 - Cordes, Andreas A1 - Costantini, Giulio A1 - Alvarez, Leslie D. Cramblet A1 - Cremata, Ed A1 - Crusius, Jan A1 - DeCoster, Jamie A1 - DeGaetano, Michelle A. A1 - Della Penna, Nicolas A1 - den Bezemer, Bobby A1 - Deserno, Marie K. A1 - Devitt, Olivia A1 - Dewitte, Laura A1 - Dobolyi, David G. A1 - Dodson, Geneva T. A1 - Donnellan, M. Brent A1 - Donohue, Ryan A1 - Dore, Rebecca A. A1 - Dorrough, Angela A1 - Dreber, Anna A1 - Dugas, Michelle A1 - Dunn, Elizabeth W. A1 - Easey, Kayleigh A1 - Eboigbe, Sylvia A1 - Eggleston, Casey A1 - Embley, Jo A1 - Epskamp, Sacha A1 - Errington, Timothy M. A1 - Estel, Vivien A1 - Farach, Frank J. A1 - Feather, Jenelle A1 - Fedor, Anna A1 - Fernandez-Castilla, Belen A1 - Fiedler, Susann A1 - Field, James G. A1 - Fitneva, Stanka A. A1 - Flagan, Taru A1 - Forest, Amanda L. A1 - Forsell, Eskil A1 - Foster, Joshua D. A1 - Frank, Michael C. A1 - Frazier, Rebecca S. A1 - Fuchs, Heather A1 - Gable, Philip A1 - Galak, Jeff A1 - Galliani, Elisa Maria A1 - Gampa, Anup A1 - Garcia, Sara A1 - Gazarian, Douglas A1 - Gilbert, Elizabeth A1 - Giner-Sorolla, Roger A1 - Glöckner, Andreas A1 - Göllner, Lars A1 - Goh, Jin X. A1 - Goldberg, Rebecca A1 - Goodbourn, Patrick T. A1 - Gordon-McKeon, Shauna A1 - Gorges, Bryan A1 - Gorges, Jessie A1 - Goss, Justin A1 - Graham, Jesse A1 - Grange, James A. A1 - Gray, Jeremy A1 - Hartgerink, Chris A1 - Hartshorne, Joshua A1 - Hasselman, Fred A1 - Hayes, Timothy A1 - Heikensten, Emma A1 - Henninger, Felix A1 - Hodsoll, John A1 - Holubar, Taylor A1 - Hoogendoorn, Gea A1 - Humphries, Denise J. A1 - Hung, Cathy O. -Y. A1 - Immelman, Nathali A1 - Irsik, Vanessa C. A1 - Jahn, Georg A1 - Jaekel, Frank A1 - Jekel, Marc A1 - Johannesson, Magnus A1 - Johnson, Larissa G. A1 - Johnson, David J. A1 - Johnson, Kate M. A1 - Johnston, William J. A1 - Jonas, Kai A1 - Joy-Gaba, Jennifer A. A1 - Kappes, Heather Barry A1 - Kelso, Kim A1 - Kidwell, Mallory C. A1 - Kim, Seung Kyung A1 - Kirkhart, Matthew A1 - Kleinberg, Bennett A1 - Knezevic, Goran A1 - Kolorz, Franziska Maria A1 - Kossakowski, Jolanda J. A1 - Krause, Robert Wilhelm A1 - Krijnen, Job A1 - Kuhlmann, Tim A1 - Kunkels, Yoram K. A1 - Kyc, Megan M. A1 - Lai, Calvin K. A1 - Laique, Aamir A1 - Lakens, Daniel A1 - Lane, Kristin A. A1 - Lassetter, Bethany A1 - Lazarevic, Ljiljana B. A1 - LeBel, Etienne P. A1 - Lee, Key Jung A1 - Lee, Minha A1 - Lemm, Kristi A1 - Levitan, Carmel A. A1 - Lewis, Melissa A1 - Lin, Lin A1 - Lin, Stephanie A1 - Lippold, Matthias A1 - Loureiro, Darren A1 - Luteijn, Ilse A1 - Mackinnon, Sean A1 - Mainard, Heather N. A1 - Marigold, Denise C. A1 - Martin, Daniel P. A1 - Martinez, Tylar A1 - Masicampo, E. J. A1 - Matacotta, Josh A1 - Mathur, Maya A1 - May, Michael A1 - Mechin, Nicole A1 - Mehta, Pranjal A1 - Meixner, Johannes A1 - Melinger, Alissa A1 - Miller, Jeremy K. A1 - Miller, Mallorie A1 - Moore, Katherine A1 - Möschl, Marcus A1 - Motyl, Matt A1 - Müller, Stephanie M. A1 - Munafo, Marcus A1 - Neijenhuijs, Koen I. A1 - Nervi, Taylor A1 - Nicolas, Gandalf A1 - Nilsonne, Gustav A1 - Nosek, Brian A. A1 - Nuijten, Michele B. A1 - Olsson, Catherine A1 - Osborne, Colleen A1 - Ostkamp, Lutz A1 - Pavel, Misha A1 - Penton-Voak, Ian S. A1 - Perna, Olivia A1 - Pernet, Cyril A1 - Perugini, Marco A1 - Pipitone, R. Nathan A1 - Pitts, Michael A1 - Plessow, Franziska A1 - Prenoveau, Jason M. A1 - Rahal, Rima-Maria A1 - Ratliff, Kate A. A1 - Reinhard, David A1 - Renkewitz, Frank A1 - Ricker, Ashley A. A1 - Rigney, Anastasia A1 - Rivers, Andrew M. A1 - Roebke, Mark A1 - Rutchick, Abraham M. A1 - Ryan, Robert S. A1 - Sahin, Onur A1 - Saide, Anondah A1 - Sandstrom, Gillian M. A1 - Santos, David A1 - Saxe, Rebecca A1 - Schlegelmilch, Rene A1 - Schmidt, Kathleen A1 - Scholz, Sabine A1 - Seibel, Larissa A1 - Selterman, Dylan Faulkner A1 - Shaki, Samuel A1 - Simpson, William B. A1 - Sinclair, H. Colleen A1 - Skorinko, Jeanine L. M. A1 - Slowik, Agnieszka A1 - Snyder, Joel S. A1 - Soderberg, Courtney A1 - Sonnleitner, Carina A1 - Spencer, Nick A1 - Spies, Jeffrey R. A1 - Steegen, Sara A1 - Stieger, Stefan A1 - Strohminger, Nina A1 - Sullivan, Gavin B. A1 - Talhelm, Thomas A1 - Tapia, Megan A1 - te Dorsthorst, Anniek A1 - Thomae, Manuela A1 - Thomas, Sarah L. A1 - Tio, Pia A1 - Traets, Frits A1 - Tsang, Steve A1 - Tuerlinckx, Francis A1 - Turchan, Paul A1 - Valasek, Milan A1 - Van Aert, Robbie A1 - van Assen, Marcel A1 - van Bork, Riet A1 - van de Ven, Mathijs A1 - van den Bergh, Don A1 - van der Hulst, Marije A1 - van Dooren, Roel A1 - van Doorn, Johnny A1 - van Renswoude, Daan R. A1 - van Rijn, Hedderik A1 - Vanpaemel, Wolf A1 - Echeverria, Alejandro Vasquez A1 - Vazquez, Melissa A1 - Velez, Natalia A1 - Vermue, Marieke A1 - Verschoor, Mark A1 - Vianello, Michelangelo A1 - Voracek, Martin A1 - Vuu, Gina A1 - Wagenmakers, Eric-Jan A1 - Weerdmeester, Joanneke A1 - Welsh, Ashlee A1 - Westgate, Erin C. A1 - Wissink, Joeri A1 - Wood, Michael A1 - Woods, Andy A1 - Wright, Emily A1 - Wu, Sining A1 - Zeelenberg, Marcel A1 - Zuni, Kellylynn T1 - Estimating the reproducibility of psychological science JF - Science N2 - Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams. Y1 - 2015 U6 - https://doi.org/10.1126/science.aac4716 SN - 1095-9203 SN - 0036-8075 VL - 349 IS - 6251 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Szameitat, Ulrike A1 - Kampe, Heike A1 - Eckardt, Barbara A1 - Görlich, Petra A1 - Haller, Silja A1 - Rost, Sophia A1 - Müller, Sarah A1 - Sütterlin, Sabine A1 - Winter, Nora A1 - Jäger, Sophie A1 - Zimmermann, Matthias T1 - Portal = Gesellschaft im Wandel: Zukunftsaufgabe Inklusion BT - Das Potsdamer Universitätsmagazin N2 - Aus dem Inhalt: - Gesellschaft im Wandel: Zukunftsaufgabe Inklusion - Mit Kopf und Füßen - Du bist, was du guckst T3 - Portal: Das Potsdamer Universitätsmagazin - 03/2013 Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440531 SN - 1618-6893 IS - 03/2013 ER - TY - JOUR A1 - Grott, Matthias A1 - Knollenberg, J. A1 - Hamm, M. A1 - Ogawa, K. A1 - Jaumann, R. A1 - Otto, Katharina Alexandra A1 - Delbo, M. A1 - Michel, Patrick A1 - Biele, J. A1 - Neumann, Wladimir A1 - Knapmeyer, Martin A1 - Kührt, E. A1 - Senshu, H. A1 - Okada, T. A1 - Helbert, Jorn A1 - Maturilli, A. A1 - Müller, N. A1 - Hagermann, A. A1 - Sakatani, Naoya A1 - Tanaka, S. A1 - Arai, T. A1 - Mottola, Stefano A1 - Tachibana, Shogo A1 - Pelivan, Ivanka A1 - Drube, Line A1 - Vincent, J-B A1 - Yano, Hajime A1 - Pilorget, C. A1 - Matz, K. D. A1 - Schmitz, N. A1 - Koncz, A. A1 - Schröder, Stefan E. A1 - Trauthan, F. A1 - Schlotterer, Markus A1 - Krause, C. A1 - Ho, T-M A1 - Moussi-Soffys, A. T1 - Low thermal conductivity boulder with high porosity identified on C-type asteroid (162173) Ryugu JF - Nature astronomy N2 - C-type asteroids are among the most pristine objects in the Solar System, but little is known about their interior structure and surface properties. Telescopic thermal infrared observations have so far been interpreted in terms of a regolith-covered surface with low thermal conductivity and particle sizes in the centimetre range. This includes observations of C-type asteroid (162173) Ryugu1,2,3. However, on arrival of the Hayabusa2 spacecraft at Ryugu, a regolith cover of sand- to pebble-sized particles was found to be absent4,5 (R.J. et al., manuscript in preparation). Rather, the surface is largely covered by cobbles and boulders, seemingly incompatible with the remote-sensing infrared observations. Here we report on in situ thermal infrared observations of a boulder on the C-type asteroid Ryugu. We found that the boulder’s thermal inertia was much lower than anticipated based on laboratory measurements of meteorites, and that a surface covered by such low-conductivity boulders would be consistent with remote-sensing observations. Our results furthermore indicate high boulder porosities as well as a low tensile strength in the few hundred kilopascal range. The predicted low tensile strength confirms the suspected observational bias6 in our meteorite collections, as such asteroidal material would be too frail to survive atmospheric entry7 Y1 - 2019 U6 - https://doi.org/10.1038/s41550-019-0832-x SN - 2397-3366 VL - 3 IS - 11 SP - 971 EP - 976 PB - Nature Publishing Group CY - London ER - TY - JOUR A1 - Grott, Matthias A1 - Knollenberg, J. A1 - Hamm, M. A1 - Ogawa, K. A1 - Jaumann, R. A1 - Otto, Katharina Alexandra A1 - Delbo, M. A1 - Michel, P. A1 - Biele, J. A1 - Neumann, W. A1 - Knapmeyer, M. A1 - Kuehrt, E. A1 - Senshu, H. A1 - Okada, T. A1 - Helbert, J. A1 - Maturilli, A. A1 - Müller, N. A1 - Hagermann, A. A1 - Sakatani, N. A1 - Tanaka, S. A1 - Arai, T. A1 - Mottola, S. A1 - Tachibana, S. A1 - Pelivan, Ivanka A1 - Drube, L. A1 - Vincent, J-B A1 - Yano, H. A1 - Pilorget, C. A1 - Matz, K. D. A1 - Schmitz, N. A1 - Koncz, A. A1 - Schröder, S. E. A1 - Trauthan, F. A1 - Schlotterer, M. A1 - Krause, C. A1 - Ho, T-M A1 - Moussi-Soffys, A. T1 - Low thermal conductivity boulder with high porosity identified on C-type asteroid (162173) Ryugu JF - Nature astronomy N2 - C-type asteroids are among the most pristine objects in the Solar System, but little is known about their interior structure and surface properties. Telescopic thermal infrared observations have so far been interpreted in terms of a regolith-covered surface with low thermal conductivity and particle sizes in the centimetre range. This includes observations of C-type asteroid (162173) Ryugu1,2,3. However, on arrival of the Hayabusa2 spacecraft at Ryugu, a regolith cover of sand- to pebble-sized particles was found to be absent4,5 (R.J. et al., manuscript in preparation). Rather, the surface is largely covered by cobbles and boulders, seemingly incompatible with the remote-sensing infrared observations. Here we report on in situ thermal infrared observations of a boulder on the C-type asteroid Ryugu. We found that the boulder’s thermal inertia was much lower than anticipated based on laboratory measurements of meteorites, and that a surface covered by such low-conductivity boulders would be consistent with remote-sensing observations. Our results furthermore indicate high boulder porosities as well as a low tensile strength in the few hundred kilopascal range. The predicted low tensile strength confirms the suspected observational bias6 in our meteorite collections, as such asteroidal material would be too frail to survive atmospheric entry7. Y1 - 2020 U6 - https://doi.org/10.1038/s41550-019-0832-x SN - 2397-3366 VL - 3 IS - 11 SP - 971 EP - 976 PB - Nature Publishing Group CY - London ER - TY - JOUR A1 - Müller, Matthias M. A1 - Haakh, Harald R. A1 - Calarco, Tommaso A1 - Koch, Christiane P. A1 - Henkel, Carsten T1 - Prospects for fast Rydberg gates on an atom chip JF - Quantum information processing N2 - Atom chips are a promising candidate for a scalable architecture for quantum information processing provided a universal set of gates can be implemented with high fidelity. The difficult part in achieving universality is the entangling two-qubit gate. We consider a Rydberg phase gate for two atoms trapped on a chip and employ optimal control theory to find the shortest gate that still yields a reasonable gate error. Our parameters correspond to a situation where the Rydberg blockade regime is not yet reached. We discuss the role of spontaneous emission and the effect of noise from the chip surface on the atoms in the Rydberg state. KW - Optimal control KW - Phase gate KW - Rydberg atoms KW - Cavity quantum electrodynamics Y1 - 2011 U6 - https://doi.org/10.1007/s11128-011-0296-0 SN - 1570-0755 VL - 10 IS - 6 SP - 771 EP - 792 PB - Springer CY - New York ER - TY - JOUR A1 - Müller, Christian Th. A1 - Rogg, Matthias T1 - Bernhard R. Kroener und die deutsche Militärhistoriographie Y1 - 2013 SN - 978-3-506-77657-0 ER - TY - JOUR A1 - Hlinak, Andreas A1 - Müller, Thomas A1 - Kramer, Matthias A1 - Mühle, Ralf-Udo A1 - Liebherr, Helga A1 - Ziedler, Klaus T1 - Serological survey of viral pathogens in bean and white-fronted geese from Germany Y1 - 1998 SN - 0090-3558 ER -