TY - CHAP
A1 - Kurbel, Karl
A1 - Nowak, Dawid
A1 - Azodi, Amir
A1 - Jaeger, David
A1 - Meinel, Christoph
A1 - Cheng, Feng
A1 - Sapegin, Andrey
A1 - Gawron, Marian
A1 - Morelli, Frank
A1 - Stahl, Lukas
A1 - Kerl, Stefan
A1 - Janz, Mariska
A1 - Hadaya, Abdulmasih
A1 - Ivanov, Ivaylo
A1 - Wiese, Lena
A1 - Neves, Mariana
A1 - Schapranow, Matthieu-Patrick
A1 - Fähnrich, Cindy
A1 - Feinbube, Frank
A1 - Eberhardt, Felix
A1 - Hagen, Wieland
A1 - Plauth, Max
A1 - Herscheid, Lena
A1 - Polze, Andreas
A1 - Barkowsky, Matthias
A1 - Dinger, Henriette
A1 - Faber, Lukas
A1 - Montenegro, Felix
A1 - Czachórski, Tadeusz
A1 - Nycz, Monika
A1 - Nycz, Tomasz
A1 - Baader, Galina
A1 - Besner, Veronika
A1 - Hecht, Sonja
A1 - Schermann, Michael
A1 - Krcmar, Helmut
A1 - Wiradarma, Timur Pratama
A1 - Hentschel, Christian
A1 - Sack, Harald
A1 - Abramowicz, Witold
A1 - Sokolowska, Wioletta
A1 - Hossa, Tymoteusz
A1 - Opalka, Jakub
A1 - Fabisz, Karol
A1 - Kubaczyk, Mateusz
A1 - Cmil, Milena
A1 - Meng, Tianhui
A1 - Dadashnia, Sharam
A1 - Niesen, Tim
A1 - Fettke, Peter
A1 - Loos, Peter
A1 - Perscheid, Cindy
A1 - Schwarz, Christian
A1 - Schmidt, Christopher
A1 - Scholz, Matthias
A1 - Bock, Nikolai
A1 - Piller, Gunther
A1 - Böhm, Klaus
A1 - Norkus, Oliver
A1 - Clark, Brian
A1 - Friedrich, Björn
A1 - Izadpanah, Babak
A1 - Merkel, Florian
A1 - Schweer, Ilias
A1 - Zimak, Alexander
A1 - Sauer, Jürgen
A1 - Fabian, Benjamin
A1 - Tilch, Georg
A1 - Müller, David
A1 - Plöger, Sabrina
A1 - Friedrich, Christoph M.
A1 - Engels, Christoph
A1 - Amirkhanyan, Aragats
A1 - van der Walt, Estée
A1 - Eloff, J. H. P.
A1 - Scheuermann, Bernd
A1 - Weinknecht, Elisa
ED - Meinel, Christoph
ED - Polze, Andreas
ED - Oswald, Gerhard
ED - Strotmann, Rolf
ED - Seibold, Ulrich
ED - Schulzki, Bernhard
T1 - HPI Future SOC Lab
BT - Proceedings 2015
N2 - Das Future SOC Lab am HPI ist eine Kooperation des Hasso-Plattner-Instituts mit verschiedenen Industriepartnern. Seine Aufgabe ist die Ermöglichung und Förderung des Austausches zwischen Forschungsgemeinschaft und Industrie.
Am Lab wird interessierten Wissenschaftlern eine Infrastruktur von neuester Hard- und Software kostenfrei für Forschungszwecke zur Verfügung gestellt. Dazu zählen teilweise noch nicht am Markt verfügbare Technologien, die im normalen Hochschulbereich in der Regel nicht zu finanzieren wären, bspw. Server mit bis zu 64 Cores und 2 TB Hauptspeicher. Diese Angebote richten sich insbesondere an Wissenschaftler in den Gebieten Informatik und Wirtschaftsinformatik. Einige der Schwerpunkte sind Cloud Computing, Parallelisierung und In-Memory Technologien.
In diesem Technischen Bericht werden die Ergebnisse der Forschungsprojekte des Jahres 2015 vorgestellt. Ausgewählte Projekte stellten ihre Ergebnisse am 15. April 2015 und 4. November 2015 im Rahmen der Future SOC Lab Tag Veranstaltungen vor.
KW - Future SOC Lab
KW - Forschungsprojekte
KW - Multicore Architekturen
KW - In-Memory Technologie
KW - Cloud Computing
KW - maschinelles Lernen
KW - künstliche Intelligenz
Y1 - 2017
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-102516
ER -
TY - JOUR
A1 - Holdt, Hans-Jürgen
A1 - Müller, Holger
A1 - Potter, Matthias
A1 - Kelling, Alexandra
A1 - Schilde, Uwe
A1 - Starke, Ines
A1 - Heydenreich, Matthias
A1 - Kleinpeter, Erich
T1 - The first sandwich complex with an octa(thioether) coordination sphere : Bis(maleonitrile-tetrathia-12-crown- 4)silver(I)
N2 - The new tetrathiacrown ethers maleonitrile-tetrathia-12-crown-4 (mn12S(4)) and maleonitrile-tetrathia-13-crown- 4 (mn13S(4)) have been prepared and characterised by X-ray crystallographic analysis. These crown ethers form 2:1, 3:2 and 1: 1 complexes with AgY (Y = BF4, PF6). The crystal structures of [Ag(mn12S(4))(2)]BF4 (3a), [Ag(mn13S(4))(2)]BF4 (4a) and [Ag-2(mn13S(4))(3)](PF6)(2) (6b) have been determined. Compound 3a contains the centrosymmetric sandwich complex cation [Ag(mn12S(4))(2)](+) where each mn12S(4) ligand is coordinated to the Ag centre in an endo manner through all four S atoms. The 2:1 complex [Ag(mn12S(4))(2)](+) is the first sandwich complex with a tetrathiacrown ether and the first complex with an octa(thioether) coordination sphere. The crystal structure of compound 4a also reveals a 2:1 complex. This complex, [Ag(mnl3S(4))(2)](+), exhibits a half-sandwich structure. One mn13S(4) ligand coordinates to Ag+ by all four S donor atoms and the other 13S(4) crown by only one S atom. Compound 6b contains a dinuclear Ag complex. The Ag complexes 3a,b-8a,b were also studied by electrospray ionisation mass spectrometry. Collision-induced dissociation (CID) was used to compare the relative stability of 2:1 complexes [AgL2]+ and 1:1 complexes [AgL](+) (L = mn12S(4), mn13S(4)). The C-13 NMR chemical shifts of 2:1 and 1:1 Ag complexes and their corresponding free ligands were also estimated and compared. The free energy of the barrier of ring inversion (Delta G(double dagger)) for [Ag(mn12S(4))(2)](+) was determined to be 64 kJmol(-1).
Y1 - 2006
UR - http://www3.interscience.wiley.com/cgi-bin/jhome/27721/
U6 - https://doi.org/10.1002/ejic.200501109
SN - 1434-1948
ER -
TY - JOUR
A1 - Moustakas, Aristides
A1 - Günther, Matthias
A1 - Wiegand, Kerstin
A1 - Müller, Karl-Heinz
A1 - Ward, David
A1 - Meyer, Katrin M.
A1 - Jeltsch, Florian
T1 - Long-term mortality patterns of the deep-rooted Acacia erioloba
BT - The middle class shall die!
JF - Journal of vegetation science
N2 - Question: Is there a relationship between size and death in the Iona-lived, deep-rooted tree, Acacia erioloba, in a semi-arid savanna? What is the size-class distribution of A. erioloba mortality? Does the mortality distribution differ from total tree size distribution? Does A. erioloba mortality distribution match the mortality distributions recorded thus far in other environments? Location: Dronfield Ranch, near Kimberley, Kalahari, South Africa. Methods: A combination of aerial photographs and a satellite image covering 61 year was used to provide long-term spatial data on mortality. We used aerial photographs of the study area from 1940, 1964, 1984, 1993 and a satellite image from 2001 to follow three plots covering 510 ha. We were able to identify and individually follow ca. 3000 individual trees from 1940 till 2001. Results: The total number of trees increased over time. No relationship between total number of trees and mean tree size was detected. There were no trends over time in total number of deaths per plot or in size distributions of dead trees. Kolmogorov-Smirnov tests showed no differences in size class distributions for living trees through time. The size distribution of dead trees was significantly different from the size distribution of all trees present on the plots. Overall, the number of dead trees was low in small size classes, reached a peak value when canopy area was 20 - 30 m(2), and declined in lamer size-classes. Mortality as a ratio of dead vs. total trees peaked at intermediate canopy sizes too. Conclusion: A. erioloba mortality was size-dependent, peaking at intermediate sizes. The mortality distribution differs from all other tree mortality distributions recorded thus far. We suggest that a possible mechanism for this unusual mortality distribution is intraspecific competition for water in this semi-arid environment.
KW - competition
KW - long-term data
KW - remote sensing
KW - savanna
KW - size dependent mortality
KW - size distribution
KW - tree death
Y1 - 2006
U6 - https://doi.org/10.1111/j.1654-1103.2006.tb02468.x
SN - 1100-9233
VL - 17
SP - 473
EP - 480
PB - Blackwell
CY - Malden
ER -
TY - CHAP
A1 - Curzon, Paul
A1 - Kalas, Ivan
A1 - Schubert, Sigrid
A1 - Schaper, Niclas
A1 - Barnes, Jan
A1 - Kennewell, Steve
A1 - Bröker, Kathrin
A1 - Kastens, Uwe
A1 - Magenheim, Johannes
A1 - Dagiene, Valentina
A1 - Stupuriene, Gabriele
A1 - Ellis, Jason Brent
A1 - Abreu-Ellis, Carla Reis
A1 - Grillenberger, Andreas
A1 - Romeike, Ralf
A1 - Haugsbakken, Halvdan
A1 - Jones, Anthony
A1 - Lewin, Cathy
A1 - McNicol, Sarah
A1 - Nelles, Wolfgang
A1 - Neugebauer, Jonas
A1 - Ohrndorf, Laura
A1 - Schaper, Niclas
A1 - Schubert, Sigrid
A1 - Opel, Simone
A1 - Kramer, Matthias
A1 - Trommen, Michael
A1 - Pottbäcker, Florian
A1 - Ilaghef, Youssef
A1 - Passig, David
A1 - Tzuriel, David
A1 - Kedmi, Ganit Eshel
A1 - Saito, Toshinori
A1 - Webb, Mary
A1 - Weigend, Michael
A1 - Bottino, Rosa
A1 - Chioccariello, Augusto
A1 - Christensen, Rhonda
A1 - Knezek, Gerald
A1 - Gioko, Anthony Maina
A1 - Angondi, Enos Kiforo
A1 - Waga, Rosemary
A1 - Ohrndorf, Laura
A1 - Or-Bach, Rachel
A1 - Preston, Christina
A1 - Younie, Sarah
A1 - Przybylla, Mareen
A1 - Romeike, Ralf
A1 - Reynolds, Nicholas
A1 - Swainston, Andrew
A1 - Bendrups, Faye
A1 - Sysło, Maciej M.
A1 - Kwiatkowska, Anna Beata
A1 - Zieris, Holger
A1 - Gerstberger, Herbert
A1 - Müller, Wolfgang
A1 - Büchner, Steffen
A1 - Opel, Simone
A1 - Schiller, Thomas
A1 - Wegner, Christian
A1 - Zender, Raphael
A1 - Lucke, Ulrike
A1 - Diethelm, Ira
A1 - Syrbe, Jörn
A1 - Lai, Kwok-Wing
A1 - Davis, Niki
A1 - Eickelmann, Birgit
A1 - Erstad, Ola
A1 - Fisser, Petra
A1 - Gibson, David
A1 - Khaddage, Ferial
A1 - Knezek, Gerald
A1 - Micheuz, Peter
A1 - Kloos, Carlos Delgado
ED - Brinda, Torsten
ED - Reynolds, Nicholas
ED - Romeike, Ralf
ED - Schwill, Andreas
T1 - KEYCIT 2014
BT - key competencies in informatics and ICT
N2 - In our rapidly changing world it is increasingly important not only to be an expert in a chosen field of study but also to be able to respond to developments, master new approaches to solving problems, and fulfil changing requirements in the modern world and in the job market. In response to these needs key competencies in understanding, developing and using new digital technologies are being brought into focus in school and university programmes. The IFIP TC3 conference "KEYCIT – Key Competences in Informatics and ICT (KEYCIT 2014)" was held at the University of Potsdam in Germany from July 1st to 4th, 2014 and addressed the combination of key competencies, Informatics and ICT in detail. The conference was organized into strands focusing on secondary education, university education and teacher education (organized by IFIP WGs 3.1 and 3.3) and provided a forum to present and to discuss research, case studies, positions, and national perspectives in this field.
T3 - Commentarii informaticae didacticae (CID) - 7
KW - Schlüsselkompetenzen
KW - Informatik
KW - Bildung
KW - ICT
KW - Informatikdidaktik
KW - Key Competencies
KW - Informatics
KW - education
KW - ICT
KW - Computer Science Education
Y1 - 2015
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-70325
SN - 978-3-86956-292-6
PB - Universitätsverlag Potsdam
CY - Potsdam
ER -
TY - JOUR
A1 - Vogel, Heike
A1 - Kamitz, Anne
A1 - Hallahan, Nicole
A1 - Lebek, Sandra
A1 - Schallschmidt, Tanja
A1 - Jonas, Wenke
A1 - Jähnert, Markus
A1 - Gottmann, Pascal
A1 - Zellner, Lisa
A1 - Kanzleiter, Timo
A1 - Damen, Mareike
A1 - Altenhofen, Delsi
A1 - Burkhardt, Ralph
A1 - Renner, Simone
A1 - Dahlhoff, Maik
A1 - Wolf, Eckhard
A1 - Müller, Timo Dirk
A1 - Blüher, Matthias
A1 - Joost, Hans-Georg
A1 - Chadt, Alexandra
A1 - Al-Hasani, Hadi
A1 - Schürmann, Annette
T1 - A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes
JF - Human molecular genetics
N2 - To explore the genetic determinants of obesity and Type 2 diabetes (T2D), the German Center for Diabetes Research (DZD) conducted crossbreedings of the obese and diabetes-prone New Zealand Obese mouse strain with four different lean strains (B6, DBA, C3H, 129P2) that vary in their susceptibility to develop T2D. Genome-wide linkage analyses localized more than 290 quantitative trait loci (QTL) for obesity, 190 QTL for diabetes-related traits and 100 QTL for plasma metabolites in the out-cross populations. A computational framework was developed that allowed to refine critical regions and to nominate a small number of candidate genes by integrating reciprocal haplotype mapping and transcriptome data. The efficiency of the complex procedure was demonstrated for one obesity QTL. The genomic interval of 35 Mb with 502 annotated candidate genes was narrowed down to six candidates. Accordingly, congenic mice retained the obesity phenotype owing to an interval that contains three of the six candidate genes. Among these the phospholipase PLA2G4A exhibited an elevated expression in adipose tissue of obese human subjects and is therefore a critical regulator of the obesity locus. Together, our broad and complex approach demonstrates that combined- and comparative-cross analysis exhibits improved mapping resolution and represents a valid tool for the identification of disease genes.
Y1 - 2018
U6 - https://doi.org/10.1093/hmg/ddy217
SN - 0964-6906
SN - 1460-2083
VL - 27
IS - 17
SP - 3099
EP - 3112
PB - Oxford Univ. Press
CY - Oxford
ER -
TY - JOUR
A1 - Shenoy, Pradeep
A1 - Krauledat, Matthias
A1 - Blankertz, Benjamin
A1 - Rao, Rajesh P. N.
A1 - Müller, Klaus-Robert
T1 - Towards adaptive classification for BCI
N2 - Non-stationarities are ubiquitous in EEG signals. They are especially apparent in the use of EEG-based brain- computer interfaces (BCIs): (a) in the differences between the initial calibration measurement and the online operation of a BCI, or (b) caused by changes in the subject's brain processes during an experiment (e.g. due to fatigue, change of task involvement, etc). In this paper, we quantify for the first time such systematic evidence of statistical differences in data recorded during offline and online sessions. Furthermore, we propose novel techniques of investigating and visualizing data distributions, which are particularly useful for the analysis of (non-) stationarities. Our study shows that the brain signals used for control can change substantially from the offline calibration sessions to online control, and also within a single session. In addition to this general characterization of the signals, we propose several adaptive classification schemes and study their performance on data recorded during online experiments. An encouraging result of our study is that surprisingly simple adaptive methods in combination with an offline feature selection scheme can significantly increase BCI performance
Y1 - 2006
UR - http://iopscience.iop.org/1741-2552/3/1/R02/
U6 - https://doi.org/10.1088/1741-2560/3/1/R02
ER -
TY - JOUR
A1 - Blankertz, Benjamin
A1 - Dornhege, Guido
A1 - Krauledat, Matthias
A1 - Müller, Klaus-Robert
A1 - Kunzmann, Volker
A1 - Losch, Florian
A1 - Curio, Gabriel
T1 - The Berlin brain-computer interface : EEG-based communication without subject training
N2 - The Berlin Brain-Computer Interface (BBCI) project develops a noninvasive BCI system whose key features are 1) the use of well-established motor competences as control paradigms, 2) high-dimensional features from 128-channel electroencephalogram (EEG), and 3) advanced machine learning techniques. As reported earlier, our experiments demonstrate that very high information transfer rates can be achieved using the readiness potential (RP) when predicting the laterality of upcoming left-versus right-hand movements in healthy subjects. A more recent study showed that the RP similarily accompanies phantom movements in arm amputees, but the signal strength decreases with longer loss of the limb. In a complementary approach, oscillatory features are used to discriminate imagined movements (left hand versus right hand versus foot). In a recent feedback study with six healthy subjects with no or very little experience with BCI control, three subjects achieved an information transfer rate above 35 bits per minute (bpm), and further two subjects above 24 and 15 bpm, while one subject could not achieve any BCI control. These results are encouraging for an EEG-based BCI system in untrained subjects that is independent of peripheral nervous system activity and does not rely on evoked potentials even when compared to results with very well-trained subjects operating other BCI systems
Y1 - 2006
UR - http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=7333
U6 - https://doi.org/10.1109/Tnsre.2006.875557
SN - 1534-4320
ER -
TY - CHAP
A1 - Heinisch, Isabelle
A1 - Romeike, Ralf
A1 - Knobelsdorf, Maria
A1 - Kreitz, Christoph
A1 - Nylén, Aletta
A1 - Dörge, Christina
A1 - Göttel, Timo
A1 - Holz, Jan
A1 - Bergner, Nadine
A1 - Schroeder, Ulrik
A1 - Metzger, Christiane
A1 - Haag, Johann
A1 - Abke, Jörg
A1 - Schwirtlich, Vincent
A1 - Sedelmaier, Yvonne
A1 - Müller, Dorothee
A1 - Frommer, Andreas
A1 - Humbert, Ludger
A1 - Berges, Marc
A1 - Mühling, Andreas
A1 - Hubwieser, Peter
A1 - Steuer, Horst
A1 - Engbring, Dieter
A1 - Selke, Harald
A1 - Drews, Paul
A1 - Schirmer, Ingrid
A1 - Morisse, Marcel
A1 - Sagawe, Arno
A1 - Rolf, Arno
A1 - Friedemann, Stefan
A1 - Gröger, Stefan
A1 - Schumann, Matthias
A1 - Klinger, Melanie
A1 - Polutina, Olena
A1 - Bibel, Ariane
A1 - Götz, Christian
A1 - Brinda, Torsten
A1 - Apel, Rebecca
A1 - Berg, Tobias
A1 - Bergner, Nadine
A1 - Chatti, Mohamed Amine
A1 - Leicht-Scholten, Carmen
A1 - Schroeder, Ulrik
A1 - Al-Saffar, Loay Talib
A1 - Petre, Marian
A1 - Schirmer, Ingrid
A1 - Rick, Detlef
ED - Forbrig, Peter
ED - Rick, Detlef
ED - Schmolitzky, Axel
T1 - HDI 2012 – Informatik für eine nachhaltige Zukunft : 5. Fachtagung Hochschuldidaktik der Informatik ; 06.–07. November 2012, Universität Hamburg
N2 - Die Tagungsreihe zur Hochschuldidaktik der Informatik HDI wird vom Fachbereich Informatik und Ausbildung / Didaktik der Informatik (IAD) in der Gesellschaft für Informatik e. V. (GI) organisiert. Sie dient den Lehrenden der Informatik in Studiengängen an Hochschulen als Forum der Information und des Austauschs über neue didaktische Ansätze und bildungspolitische Themen im Bereich der Hochschulausbildung aus der fachlichen Perspektive der Informatik. Diese fünfte HDI 2012 wurde an der Universität Hamburg organisiert. Für sie wurde das spezielle Motto „Informatik für eine nachhaltige Zukunft“ gewählt, um insbesondere Fragen der Bildungsrelevanz informatischer Inhalte, der Kompetenzen für Studierende informatisch geprägter Studiengänge und der Rolle der Informatik in der Hochschulentwicklung zu diskutieren.
T3 - Commentarii informaticae didacticae (CID) - 5
Y1 - 2013
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-62891
SN - 978-3-86956-220-9
PB - Universitätsverlag Potsdam
CY - Potsdam
ER -
TY - GEN
A1 - Bringmann, Gerhard
A1 - Mutanyatta-Comar, Joan
A1 - Maksimenka, Katja
A1 - Wanjohi, John M.
A1 - Heydenreich, Matthias
A1 - Brun, Reto
A1 - Müller, Werner E. G.
A1 - Peter, Martin
A1 - Midiwo, Jacob O.
A1 - Yenesew, Abiy
T1 - Joziknipholones A and B : the First Dimeric Phenylanthraquinones, from the Roots of Bulbine frutescens
N2 - From the roots of the African plant Bulbine frutescens (Asphodelaceae), two unprecedented novel dimeric phenylanthraquinones, named joziknipholones A and B, possessing axial and centrochirality, were isolated, together with six known compounds. Structural elucidation of the new metabolites was achieved by spectroscopic and chiroptical methods, by reductive cleavage of the central bond between the monomeric phenylanthraquinone and -anthrone portions with sodium dithionite, and by quantum chemical CD calculations. Based on the recently revised absolute axial configuration of the parent phenylanthraquinones, knipholone and knipholone anthrone, the new dimers were attributed to possess the P-configuration (i.e., with the acetyl portions below the anthraquinone plane) at both axes in the case of joziknipholone A, whereas in joziknipholone B, the knipholone part was found to be M-configured. Joziknipholones A and B are active against the chloroquine resistant strain K1 of the malaria pathogen, Plasmodium falciparum, and show moderate activity against murine leukemic lymphoma L5178y cells.
T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 104
KW - antimalarial activity
KW - chirality
KW - joziknipholones
KW - natural products
KW - structure elucidation
Y1 - 2008
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-42638
ER -
TY - JOUR
A1 - Bringmann, Gerhard
A1 - Mutanyatta-Comar, Joan
A1 - Maksimenka, Katja
A1 - Wanjohi, John M.
A1 - Heydenreich, Matthias
A1 - Brun, Reto
A1 - Müller, Werner E. G.
A1 - Peter, Martin G.
A1 - Midiwo, Jacob O.
A1 - Yenesew, Abiy
T1 - Joziknipholones A and B : the first dimeric phenylanthraquinones, from the roots of Bulbine frutescens
N2 - From the roots of the African plant Bulbine frutescens (Asphodelaceae), two unprecedented novel dimeric phenylanthraquinones, named joziknipholones A and B, possessing axial and centrochirality, were isolated, together with six known compounds. Structural elucidation of the new metabolites was achieved by spectroscopic and chiroptical methods, by reductive cleavage of the central bond between the monomeric phenylanthraquinone and -anthrone portions with sodium dithionite, and by quantum chemical CD calculations. Based on the recently revised absolute axial configuration of the parent phenylanthraquinones, knipholone and knipholone anthrone, the new dimers were attributed to possess the P- configuration (i.e., with the acetyl portions below the anthraquinone plane) at both axes in the case of joziknipholone A, whereas in joziknipholone B, the knipholone part was found to be M-configured. Joziknipholones A and B are active against the chloroquine resistant strain K1 of the malaria pathogen, Plasmodium falciparum, and show moderate activity against murine leukemic lymphoma L5178y cells.
Y1 - 2008
UR - http://www3.interscience.wiley.com/journal/26293/home?CRETRY=1&SRETRY=0
SN - 0947-6539
ER -
TY - JOUR
A1 - Merks, Anne Margarete
A1 - Swinarski, Marie
A1 - Meyer, Alexander Matthias
A1 - Müller, Nicola Victoria
A1 - Özcan, Ismail
A1 - Donat, Stefan
A1 - Burger, Alexa
A1 - Gilbert, Stephen
A1 - Mosimann, Christian
A1 - Abdelilah-Seyfried, Salim
A1 - Panakova, Daniela
T1 - Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity
JF - Nature Communications
N2 - Development of a multiple-chambered heart from the linear heart tube is inherently linked to cardiac looping. Although many molecular factors regulating the process of cardiac chamber ballooning have been identified, the cellular mechanisms underlying the chamber formation remain unclear. Here, we demonstrate that cardiac chambers remodel by cell neighbour exchange of cardiomyocytes guided by the planar cell polarity (PCP) pathway triggered by two non-canonical Wnt ligands, Wnt5b and Wnt11. We find that PCP signalling coordinates the localisation of actomyosin activity, and thus the efficiency of cell neighbour exchange. On a tissue-scale, PCP signalling planar-polarises tissue tension by restricting the actomyosin contractility to the apical membranes of outflow tract cells. The tissue-scale polarisation of actomyosin contractility is required for cardiac looping that occurs concurrently with chamber ballooning. Taken together, our data reveal that instructive PCP signals couple cardiac chamber expansion with cardiac looping through the organ-scale polarisation of actomyosin-based tissue tension.
Y1 - 2018
U6 - https://doi.org/10.1038/s41467-018-04566-1
SN - 2041-1723
VL - 9
PB - Nature Publ. Group
CY - London
ER -
TY - JOUR
A1 - Träger, Juliane
A1 - Klamroth, Tillmann
A1 - Kelling, Alexandra
A1 - Lubahn, Susanne
A1 - Cleve, Ernst
A1 - Mickler, Wulfhard
A1 - Heydenreich, Matthias
A1 - Müller, Holger
A1 - Holdt, Hans-Jürgen
T1 - Complexation of Palladium(II) with unsaturated Dithioethers a systematic development of highly selective ligands for solvent extraction
JF - European journal of inorganic chemistry : a journal of ChemPubSoc Europe
N2 - There is a demand for new and robust PdII extractants due to growing recycling rates. Chelating dithioethers are promising substances for solvent extraction as they form stable square-planar complexes with PdII. We have modified unsaturated dithioethers, which are known to coordinate PdII, and adapted them to the requirements of industrial practice. The ligands are analogues of 1,2-dithioethene with varying electron-withdrawing backbones and polar end-groups. The crystal structures of several ligands and their palladium complexes were determined as well as their electro- and photochemical properties, complex stability and behaviour in solution. Solvent extraction experiments showed the superiority of some of our ligands over conventionally used extractants in terms of their very fast reaction rates. With highly selective 1,2-bis(2-methoxyethylthio)benzene (4) it is possible to extract PdII from a highly acidic medium in the presence of other base and palladium-group metals.
KW - Renewable resources
KW - Palladium
KW - Chelates
KW - Ligand design
KW - S li-gands
Y1 - 2012
U6 - https://doi.org/10.1002/ejic.201101406
SN - 1434-1948
IS - 14
SP - 2341
EP - 2352
PB - Wiley-VCH
CY - Weinheim
ER -
TY - JOUR
A1 - Debatin, Franziska
A1 - Thomas, Arne
A1 - Kelling, Alexandra
A1 - Hedin, Niklas
A1 - Bacsik, Zoltan
A1 - Senkovska, Irena
A1 - Kaskel, Stefan
A1 - Junginger, Matthias
A1 - Müller, Holger
A1 - Schilde, Uwe
A1 - Jäger, Christian
A1 - Friedrich, Alwin
A1 - Holdt, Hans-Jürgen
T1 - In situ synthesis of an imidazolate-4-amide-5-imidate ligand and formation of a microporous zinc-organic framework with H2-and CO2-storage ability
N2 - Narrow channels with polar walls are the structural and functional features responsible for the high capacity of a zinc-organic framework based on an imidazolate-amide-imidate ligand for the uptake of H2 and CO2 (see structure: orange Zn, blue N, red O, dark gray C, light gray H). The rigid and stable chelating ligand was synthesized in situ by partial hydrolysis of a dicyanoimidazole compound.
Y1 - 2010
UR - http://www3.interscience.wiley.com/cgi-bin/jhome/26737/
U6 - https://doi.org/10.1002/anie.200906188
SN - 1433-7851
ER -
TY - JOUR
A1 - Aarts, Alexander A.
A1 - Anderson, Joanna E.
A1 - Anderson, Christopher J.
A1 - Attridge, Peter R.
A1 - Attwood, Angela
A1 - Axt, Jordan
A1 - Babel, Molly
A1 - Bahnik, Stepan
A1 - Baranski, Erica
A1 - Barnett-Cowan, Michael
A1 - Bartmess, Elizabeth
A1 - Beer, Jennifer
A1 - Bell, Raoul
A1 - Bentley, Heather
A1 - Beyan, Leah
A1 - Binion, Grace
A1 - Borsboom, Denny
A1 - Bosch, Annick
A1 - Bosco, Frank A.
A1 - Bowman, Sara D.
A1 - Brandt, Mark J.
A1 - Braswell, Erin
A1 - Brohmer, Hilmar
A1 - Brown, Benjamin T.
A1 - Brown, Kristina
A1 - Bruening, Jovita
A1 - Calhoun-Sauls, Ann
A1 - Callahan, Shannon P.
A1 - Chagnon, Elizabeth
A1 - Chandler, Jesse
A1 - Chartier, Christopher R.
A1 - Cheung, Felix
A1 - Christopherson, Cody D.
A1 - Cillessen, Linda
A1 - Clay, Russ
A1 - Cleary, Hayley
A1 - Cloud, Mark D.
A1 - Cohn, Michael
A1 - Cohoon, Johanna
A1 - Columbus, Simon
A1 - Cordes, Andreas
A1 - Costantini, Giulio
A1 - Alvarez, Leslie D. Cramblet
A1 - Cremata, Ed
A1 - Crusius, Jan
A1 - DeCoster, Jamie
A1 - DeGaetano, Michelle A.
A1 - Della Penna, Nicolas
A1 - den Bezemer, Bobby
A1 - Deserno, Marie K.
A1 - Devitt, Olivia
A1 - Dewitte, Laura
A1 - Dobolyi, David G.
A1 - Dodson, Geneva T.
A1 - Donnellan, M. Brent
A1 - Donohue, Ryan
A1 - Dore, Rebecca A.
A1 - Dorrough, Angela
A1 - Dreber, Anna
A1 - Dugas, Michelle
A1 - Dunn, Elizabeth W.
A1 - Easey, Kayleigh
A1 - Eboigbe, Sylvia
A1 - Eggleston, Casey
A1 - Embley, Jo
A1 - Epskamp, Sacha
A1 - Errington, Timothy M.
A1 - Estel, Vivien
A1 - Farach, Frank J.
A1 - Feather, Jenelle
A1 - Fedor, Anna
A1 - Fernandez-Castilla, Belen
A1 - Fiedler, Susann
A1 - Field, James G.
A1 - Fitneva, Stanka A.
A1 - Flagan, Taru
A1 - Forest, Amanda L.
A1 - Forsell, Eskil
A1 - Foster, Joshua D.
A1 - Frank, Michael C.
A1 - Frazier, Rebecca S.
A1 - Fuchs, Heather
A1 - Gable, Philip
A1 - Galak, Jeff
A1 - Galliani, Elisa Maria
A1 - Gampa, Anup
A1 - Garcia, Sara
A1 - Gazarian, Douglas
A1 - Gilbert, Elizabeth
A1 - Giner-Sorolla, Roger
A1 - Glöckner, Andreas
A1 - Göllner, Lars
A1 - Goh, Jin X.
A1 - Goldberg, Rebecca
A1 - Goodbourn, Patrick T.
A1 - Gordon-McKeon, Shauna
A1 - Gorges, Bryan
A1 - Gorges, Jessie
A1 - Goss, Justin
A1 - Graham, Jesse
A1 - Grange, James A.
A1 - Gray, Jeremy
A1 - Hartgerink, Chris
A1 - Hartshorne, Joshua
A1 - Hasselman, Fred
A1 - Hayes, Timothy
A1 - Heikensten, Emma
A1 - Henninger, Felix
A1 - Hodsoll, John
A1 - Holubar, Taylor
A1 - Hoogendoorn, Gea
A1 - Humphries, Denise J.
A1 - Hung, Cathy O. -Y.
A1 - Immelman, Nathali
A1 - Irsik, Vanessa C.
A1 - Jahn, Georg
A1 - Jaekel, Frank
A1 - Jekel, Marc
A1 - Johannesson, Magnus
A1 - Johnson, Larissa G.
A1 - Johnson, David J.
A1 - Johnson, Kate M.
A1 - Johnston, William J.
A1 - Jonas, Kai
A1 - Joy-Gaba, Jennifer A.
A1 - Kappes, Heather Barry
A1 - Kelso, Kim
A1 - Kidwell, Mallory C.
A1 - Kim, Seung Kyung
A1 - Kirkhart, Matthew
A1 - Kleinberg, Bennett
A1 - Knezevic, Goran
A1 - Kolorz, Franziska Maria
A1 - Kossakowski, Jolanda J.
A1 - Krause, Robert Wilhelm
A1 - Krijnen, Job
A1 - Kuhlmann, Tim
A1 - Kunkels, Yoram K.
A1 - Kyc, Megan M.
A1 - Lai, Calvin K.
A1 - Laique, Aamir
A1 - Lakens, Daniel
A1 - Lane, Kristin A.
A1 - Lassetter, Bethany
A1 - Lazarevic, Ljiljana B.
A1 - LeBel, Etienne P.
A1 - Lee, Key Jung
A1 - Lee, Minha
A1 - Lemm, Kristi
A1 - Levitan, Carmel A.
A1 - Lewis, Melissa
A1 - Lin, Lin
A1 - Lin, Stephanie
A1 - Lippold, Matthias
A1 - Loureiro, Darren
A1 - Luteijn, Ilse
A1 - Mackinnon, Sean
A1 - Mainard, Heather N.
A1 - Marigold, Denise C.
A1 - Martin, Daniel P.
A1 - Martinez, Tylar
A1 - Masicampo, E. J.
A1 - Matacotta, Josh
A1 - Mathur, Maya
A1 - May, Michael
A1 - Mechin, Nicole
A1 - Mehta, Pranjal
A1 - Meixner, Johannes
A1 - Melinger, Alissa
A1 - Miller, Jeremy K.
A1 - Miller, Mallorie
A1 - Moore, Katherine
A1 - Möschl, Marcus
A1 - Motyl, Matt
A1 - Müller, Stephanie M.
A1 - Munafo, Marcus
A1 - Neijenhuijs, Koen I.
A1 - Nervi, Taylor
A1 - Nicolas, Gandalf
A1 - Nilsonne, Gustav
A1 - Nosek, Brian A.
A1 - Nuijten, Michele B.
A1 - Olsson, Catherine
A1 - Osborne, Colleen
A1 - Ostkamp, Lutz
A1 - Pavel, Misha
A1 - Penton-Voak, Ian S.
A1 - Perna, Olivia
A1 - Pernet, Cyril
A1 - Perugini, Marco
A1 - Pipitone, R. Nathan
A1 - Pitts, Michael
A1 - Plessow, Franziska
A1 - Prenoveau, Jason M.
A1 - Rahal, Rima-Maria
A1 - Ratliff, Kate A.
A1 - Reinhard, David
A1 - Renkewitz, Frank
A1 - Ricker, Ashley A.
A1 - Rigney, Anastasia
A1 - Rivers, Andrew M.
A1 - Roebke, Mark
A1 - Rutchick, Abraham M.
A1 - Ryan, Robert S.
A1 - Sahin, Onur
A1 - Saide, Anondah
A1 - Sandstrom, Gillian M.
A1 - Santos, David
A1 - Saxe, Rebecca
A1 - Schlegelmilch, Rene
A1 - Schmidt, Kathleen
A1 - Scholz, Sabine
A1 - Seibel, Larissa
A1 - Selterman, Dylan Faulkner
A1 - Shaki, Samuel
A1 - Simpson, William B.
A1 - Sinclair, H. Colleen
A1 - Skorinko, Jeanine L. M.
A1 - Slowik, Agnieszka
A1 - Snyder, Joel S.
A1 - Soderberg, Courtney
A1 - Sonnleitner, Carina
A1 - Spencer, Nick
A1 - Spies, Jeffrey R.
A1 - Steegen, Sara
A1 - Stieger, Stefan
A1 - Strohminger, Nina
A1 - Sullivan, Gavin B.
A1 - Talhelm, Thomas
A1 - Tapia, Megan
A1 - te Dorsthorst, Anniek
A1 - Thomae, Manuela
A1 - Thomas, Sarah L.
A1 - Tio, Pia
A1 - Traets, Frits
A1 - Tsang, Steve
A1 - Tuerlinckx, Francis
A1 - Turchan, Paul
A1 - Valasek, Milan
A1 - Van Aert, Robbie
A1 - van Assen, Marcel
A1 - van Bork, Riet
A1 - van de Ven, Mathijs
A1 - van den Bergh, Don
A1 - van der Hulst, Marije
A1 - van Dooren, Roel
A1 - van Doorn, Johnny
A1 - van Renswoude, Daan R.
A1 - van Rijn, Hedderik
A1 - Vanpaemel, Wolf
A1 - Echeverria, Alejandro Vasquez
A1 - Vazquez, Melissa
A1 - Velez, Natalia
A1 - Vermue, Marieke
A1 - Verschoor, Mark
A1 - Vianello, Michelangelo
A1 - Voracek, Martin
A1 - Vuu, Gina
A1 - Wagenmakers, Eric-Jan
A1 - Weerdmeester, Joanneke
A1 - Welsh, Ashlee
A1 - Westgate, Erin C.
A1 - Wissink, Joeri
A1 - Wood, Michael
A1 - Woods, Andy
A1 - Wright, Emily
A1 - Wu, Sining
A1 - Zeelenberg, Marcel
A1 - Zuni, Kellylynn
T1 - Estimating the reproducibility of psychological science
JF - Science
N2 - Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams.
Y1 - 2015
U6 - https://doi.org/10.1126/science.aac4716
SN - 1095-9203
SN - 0036-8075
VL - 349
IS - 6251
PB - American Assoc. for the Advancement of Science
CY - Washington
ER -
TY - JOUR
A1 - Szameitat, Ulrike
A1 - Kampe, Heike
A1 - Eckardt, Barbara
A1 - Görlich, Petra
A1 - Haller, Silja
A1 - Rost, Sophia
A1 - Müller, Sarah
A1 - Sütterlin, Sabine
A1 - Winter, Nora
A1 - Jäger, Sophie
A1 - Zimmermann, Matthias
T1 - Portal = Gesellschaft im Wandel: Zukunftsaufgabe Inklusion
BT - Das Potsdamer Universitätsmagazin
N2 - Aus dem Inhalt:
- Gesellschaft im Wandel: Zukunftsaufgabe Inklusion
- Mit Kopf und Füßen
- Du bist, was du guckst
T3 - Portal: Das Potsdamer Universitätsmagazin - 03/2013
Y1 - 2013
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440531
SN - 1618-6893
IS - 03/2013
ER -
TY - JOUR
A1 - Grott, Matthias
A1 - Knollenberg, J.
A1 - Hamm, M.
A1 - Ogawa, K.
A1 - Jaumann, R.
A1 - Otto, Katharina Alexandra
A1 - Delbo, M.
A1 - Michel, Patrick
A1 - Biele, J.
A1 - Neumann, Wladimir
A1 - Knapmeyer, Martin
A1 - Kührt, E.
A1 - Senshu, H.
A1 - Okada, T.
A1 - Helbert, Jorn
A1 - Maturilli, A.
A1 - Müller, N.
A1 - Hagermann, A.
A1 - Sakatani, Naoya
A1 - Tanaka, S.
A1 - Arai, T.
A1 - Mottola, Stefano
A1 - Tachibana, Shogo
A1 - Pelivan, Ivanka
A1 - Drube, Line
A1 - Vincent, J-B
A1 - Yano, Hajime
A1 - Pilorget, C.
A1 - Matz, K. D.
A1 - Schmitz, N.
A1 - Koncz, A.
A1 - Schröder, Stefan E.
A1 - Trauthan, F.
A1 - Schlotterer, Markus
A1 - Krause, C.
A1 - Ho, T-M
A1 - Moussi-Soffys, A.
T1 - Low thermal conductivity boulder with high porosity identified on C-type asteroid (162173) Ryugu
JF - Nature astronomy
N2 - C-type asteroids are among the most pristine objects in the Solar System, but little is known about their interior structure and surface properties. Telescopic thermal infrared observations have so far been interpreted in terms of a regolith-covered surface with low thermal conductivity and particle sizes in the centimetre range. This includes observations of C-type asteroid (162173) Ryugu1,2,3. However, on arrival of the Hayabusa2 spacecraft at Ryugu, a regolith cover of sand- to pebble-sized particles was found to be absent4,5 (R.J. et al., manuscript in preparation). Rather, the surface is largely covered by cobbles and boulders, seemingly incompatible with the remote-sensing infrared observations. Here we report on in situ thermal infrared observations of a boulder on the C-type asteroid Ryugu. We found that the boulder’s thermal inertia was much lower than anticipated based on laboratory measurements of meteorites, and that a surface covered by such low-conductivity boulders would be consistent with remote-sensing observations. Our results furthermore indicate high boulder porosities as well as a low tensile strength in the few hundred kilopascal range. The predicted low tensile strength confirms the suspected observational bias6 in our meteorite collections, as such asteroidal material would be too frail to survive atmospheric entry7
Y1 - 2019
U6 - https://doi.org/10.1038/s41550-019-0832-x
SN - 2397-3366
VL - 3
IS - 11
SP - 971
EP - 976
PB - Nature Publishing Group
CY - London
ER -
TY - JOUR
A1 - Grott, Matthias
A1 - Knollenberg, J.
A1 - Hamm, M.
A1 - Ogawa, K.
A1 - Jaumann, R.
A1 - Otto, Katharina Alexandra
A1 - Delbo, M.
A1 - Michel, P.
A1 - Biele, J.
A1 - Neumann, W.
A1 - Knapmeyer, M.
A1 - Kuehrt, E.
A1 - Senshu, H.
A1 - Okada, T.
A1 - Helbert, J.
A1 - Maturilli, A.
A1 - Müller, N.
A1 - Hagermann, A.
A1 - Sakatani, N.
A1 - Tanaka, S.
A1 - Arai, T.
A1 - Mottola, S.
A1 - Tachibana, S.
A1 - Pelivan, Ivanka
A1 - Drube, L.
A1 - Vincent, J-B
A1 - Yano, H.
A1 - Pilorget, C.
A1 - Matz, K. D.
A1 - Schmitz, N.
A1 - Koncz, A.
A1 - Schröder, S. E.
A1 - Trauthan, F.
A1 - Schlotterer, M.
A1 - Krause, C.
A1 - Ho, T-M
A1 - Moussi-Soffys, A.
T1 - Low thermal conductivity boulder with high porosity identified on C-type asteroid (162173) Ryugu
JF - Nature astronomy
N2 - C-type asteroids are among the most pristine objects in the Solar System, but little is known about their interior structure and surface properties. Telescopic thermal infrared observations have so far been interpreted in terms of a regolith-covered surface with low thermal conductivity and particle sizes in the centimetre range. This includes observations of C-type asteroid (162173) Ryugu1,2,3. However, on arrival of the Hayabusa2 spacecraft at Ryugu, a regolith cover of sand- to pebble-sized particles was found to be absent4,5 (R.J. et al., manuscript in preparation). Rather, the surface is largely covered by cobbles and boulders, seemingly incompatible with the remote-sensing infrared observations. Here we report on in situ thermal infrared observations of a boulder on the C-type asteroid Ryugu. We found that the boulder’s thermal inertia was much lower than anticipated based on laboratory measurements of meteorites, and that a surface covered by such low-conductivity boulders would be consistent with remote-sensing observations. Our results furthermore indicate high boulder porosities as well as a low tensile strength in the few hundred kilopascal range. The predicted low tensile strength confirms the suspected observational bias6 in our meteorite collections, as such asteroidal material would be too frail to survive atmospheric entry7.
Y1 - 2020
U6 - https://doi.org/10.1038/s41550-019-0832-x
SN - 2397-3366
VL - 3
IS - 11
SP - 971
EP - 976
PB - Nature Publishing Group
CY - London
ER -
TY - JOUR
A1 - Müller, Matthias M.
A1 - Haakh, Harald R.
A1 - Calarco, Tommaso
A1 - Koch, Christiane P.
A1 - Henkel, Carsten
T1 - Prospects for fast Rydberg gates on an atom chip
JF - Quantum information processing
N2 - Atom chips are a promising candidate for a scalable architecture for quantum information processing provided a universal set of gates can be implemented with high fidelity. The difficult part in achieving universality is the entangling two-qubit gate. We consider a Rydberg phase gate for two atoms trapped on a chip and employ optimal control theory to find the shortest gate that still yields a reasonable gate error. Our parameters correspond to a situation where the Rydberg blockade regime is not yet reached. We discuss the role of spontaneous emission and the effect of noise from the chip surface on the atoms in the Rydberg state.
KW - Optimal control
KW - Phase gate
KW - Rydberg atoms
KW - Cavity quantum electrodynamics
Y1 - 2011
U6 - https://doi.org/10.1007/s11128-011-0296-0
SN - 1570-0755
VL - 10
IS - 6
SP - 771
EP - 792
PB - Springer
CY - New York
ER -
TY - JOUR
A1 - Müller, Christian Th.
A1 - Rogg, Matthias
T1 - Bernhard R. Kroener und die deutsche Militärhistoriographie
Y1 - 2013
SN - 978-3-506-77657-0
ER -
TY - JOUR
A1 - Hlinak, Andreas
A1 - Müller, Thomas
A1 - Kramer, Matthias
A1 - Mühle, Ralf-Udo
A1 - Liebherr, Helga
A1 - Ziedler, Klaus
T1 - Serological survey of viral pathogens in bean and white-fronted geese from Germany
Y1 - 1998
SN - 0090-3558
ER -
TY - JOUR
A1 - Kruckenberg, Helmut
A1 - Müller, Thomas
A1 - Freuling, Conrad
A1 - Mühle, Ralf-Udo
A1 - Globig, Anja
A1 - Schirrmeier, Horst
A1 - Buss, Melanie
A1 - Harder, Timm
A1 - Kramer, Matthias
A1 - Teske, Kathrin
A1 - Polderdijk, Kees
A1 - Wallschläger, Hans-Dieter
A1 - Hlinak, Andreas
T1 - Serological and virological survey and resighting of marked wild geese in Germany
JF - European journal of wildlife research
N2 - In order to investigate the potential role of arctic geese in the epidemiology, the spatial and temporal spread of selected avian diseases, in autumn 2002, a virological and serological survey designed as capture-mark-resighting study was conducted in one of the most important coastal resting sites for migratory waterfowl in Germany. Orophatyngeal, cloacal swabs and blood samples were collected from a total of 147 birds comprising of three different arctic geese species including White-fronted Goose (Anser albifrons), Tundra Bean Goose (Anser fabalis rossicus), Pink-footed Goose (Anser brachyrhynchus) as well as from 29 non-migratory Canada Geese (Branta canadensis). Altogether, six adeno-like viruses (ALV; 95% CI, 1.74-9.92%) and two avian paramyxoviruses (APMV-4; 95% Cl, 0.19-5.53%) were isolated mainly from juvenile White-fronted Geese. In addition, four Canada Geese were infected with lentogenic APMV-1 (95% CI, 3.89-31.66%) at the date of sampling. No avian influenza viruses, reo-like viruses could be isolated despite serological evidence. Likewise, no evidence of current or previous infection by West Nile virus was found. Of the 147 birds tagged in the following years, 137 birds were resighted between 2002 and 2008 accumulating to 1925 sightings. About 90% of all sightings were reported from the main wintering and resting sites in Germany and The Netherlands. Eight of the resighted geese were virus positive (ALV and APMV-4) at the time point of sampling in 2002.
KW - Wild geese
KW - Anser albifrons
KW - White-fronted goose
KW - Disease
KW - Spatial distribution
KW - Winter
KW - Distribution
KW - Branta canadensis
KW - Canada goose
KW - Virus
KW - Infection
KW - Neckbanding
Y1 - 2011
U6 - https://doi.org/10.1007/s10344-011-0514-1
SN - 1612-4642
VL - 57
IS - 5
SP - 1025
EP - 1032
PB - Springer
CY - New York
ER -
TY - CHAP
A1 - Petersen, Hans-Georg
A1 - Brunner, Johann K.
A1 - Hüther, Michael
A1 - Müller, Matthias
A1 - Schäfer, Bernd
A1 - Bork, Christhart
T1 - Taxes, transfers, economic efficiency and social justice : essays on public economics 1979 – 2009. - Chapter 5: Group- and microsimulation
N2 - This volume contains the articles and papers which predominately have been published in international journals or edited volumes in the period from 1979 to 2009. The single articles reflect the main research areas of the editor and his co-authors who were engaged at the Kiel Institute of World Economics, the Johannes-Kepler-University Linz/Austria, the Justus- Liebig-University Giessen, the University of Potsdam, and the German Institute for Economic Research (DIW Berlin).
Y1 - 2011
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-50410
ER -
TY - JOUR
A1 - Soliveres, Santiago
A1 - van der Plas, Fons
A1 - Manning, Peter
A1 - Prati, Daniel
A1 - Gossner, Martin M.
A1 - Renner, Swen C.
A1 - Alt, Fabian
A1 - Arndt, Hartmut
A1 - Baumgartner, Vanessa
A1 - Binkenstein, Julia
A1 - Birkhofer, Klaus
A1 - Blaser, Stefan
A1 - Blüthgen, Nico
A1 - Boch, Steffen
A1 - Böhm, Stefan
A1 - Börschig, Carmen
A1 - Buscot, Francois
A1 - Diekötter, Tim
A1 - Heinze, Johannes
A1 - Hölzel, Norbert
A1 - Jung, Kirsten
A1 - Klaus, Valentin H.
A1 - Kleinebecker, Till
A1 - Klemmer, Sandra
A1 - Krauss, Jochen
A1 - Lange, Markus
A1 - Morris, E. Kathryn
A1 - Müller, Jörg
A1 - Oelmann, Yvonne
A1 - Overmann, Jörg
A1 - Pasalic, Esther
A1 - Rillig, Matthias C.
A1 - Schaefer, H. Martin
A1 - Schloter, Michael
A1 - Schmitt, Barbara
A1 - Schöning, Ingo
A1 - Schrumpf, Marion
A1 - Sikorski, Johannes
A1 - Socher, Stephanie A.
A1 - Solly, Emily F.
A1 - Sonnemann, Ilja
A1 - Sorkau, Elisabeth
A1 - Steckel, Juliane
A1 - Steffan-Dewenter, Ingolf
A1 - Stempfhuber, Barbara
A1 - Tschapka, Marco
A1 - Türke, Manfred
A1 - Venter, Paul C.
A1 - Weiner, Christiane N.
A1 - Weisser, Wolfgang W.
A1 - Werner, Michael
A1 - Westphal, Catrin
A1 - Wilcke, Wolfgang
A1 - Wolters, Volkmar
A1 - Wubet, Tesfaye
A1 - Wurst, Susanne
A1 - Fischer, Markus
A1 - Allan, Eric
T1 - Biodiversity at multiple trophic levels is needed for ecosystem multifunctionality
JF - Nature : the international weekly journal of science
Y1 - 2016
U6 - https://doi.org/10.1038/nature19092
SN - 0028-0836
SN - 1476-4687
VL - 536
SP - 456
EP - +
PB - Nature Publ. Group
CY - London
ER -
TY - JOUR
A1 - Hlinak, Andreas
A1 - Müller, Thomas
A1 - Kramer, Matthias
A1 - Mühle, Ralf-Udo
A1 - Liebherr, Helga
A1 - Ziedler, Klaus
T1 - A descriptive analysis of the potenrial association between migration patterns of bean and white-fronted geese and the occurence of newcastle disease outbreaks in domestic birds
N2 - Sightings and migration patterns of 65 bean and 65 white-fronted geese are reported. These geese were tagged and serologically screened. 19 of the 53 birds sighted had serologic evidence of Newcastle Disease. The migration patterns of the wild geese provided further evidence that the main resting and wintering sites of migratory waterfowl are likely to be important for the inter- and intraspecies transmission of avian diseases.
Y1 - 1999
SN - 0005-2086
ER -
TY - JOUR
A1 - Dornhege, Guido
A1 - Blankertz, Benjamin
A1 - Krauledat, Matthias
A1 - Losch, Florian
A1 - Curio, Gabriel
A1 - Müller, Klaus-Robert
T1 - Combined optimization of spatial and temporal filters for improving brain-computer interfacing
JF - IEEE transactions on bio-medical electronics
N2 - Brain-computer interface (BCI) systems create a novel communication channel from the brain to an output de ice by bypassing conventional motor output pathways of nerves and muscles. Therefore they could provide a new communication and control option for paralyzed patients. Modern BCI technology is essentially based on techniques for the classification of single-trial brain signals. Here we present a novel technique that allows the simultaneous optimization of a spatial and a spectral filter enhancing discriminability rates of multichannel EEG single-trials. The evaluation of 60 experiments involving 22 different subjects demonstrates the significant superiority of the proposed algorithm over to its classical counterpart: the median classification error rate was decreased by 11%. Apart from the enhanced classification, the spatial and/or the spectral filter that are determined by the algorithm can also be used for further analysis of the data, e.g., for source localization of the respective brain rhythms.
KW - brain-computer interface
KW - common spatial patterns
KW - EEG
KW - event-related desynchronization
KW - single-trial-analysis
Y1 - 2006
U6 - https://doi.org/10.1109/TBME.2006.883649
SN - 0018-9294
VL - 53
IS - 11
SP - 2274
EP - 2281
PB - IEEE
CY - New York
ER -
TY - JOUR
A1 - Sree, K. Sowjanya
A1 - Keresztes, Aron
A1 - Müller-Röber, Bernd
A1 - Brandt, Ronny
A1 - Eberius, Matthias
A1 - Fischer, Wolfgang
A1 - Appenroth, Klaus-J.
T1 - Phytotoxicity of cobalt ions on the duckweed Lemna minor - Morphology, ion uptake, and starch accumulation
JF - Chemosphere : chemistry, biology and toxicology as related to environmental problems
N2 - Cobalt (Co2+) inhibits vegetative growth of Lemna minor gradually from 1 mu M to 100 mu M. Fronds accumulated up to 21 mg Co2+ g(-1) dry weight at 10 mu M external Co2+ indicating hyperaccumulation. Interestingly, accumulation of Co2+ did not decrease the iron (Fe) content in fronds, highlighting L. minor as a suitable system for studying effects of Co2+ undisturbed by Fe deficiency symptoms unlike most other plants. Digital image analysis revealed the size distribution of fronds after Co2+ treatment and also a reduction in pigmentation of newly formed daughter fronds unlike the mother fronds during the 7-day treatment. Neither chlorophyll nor photosystem II fluorescence changed significantly during the initial 4 d, indicating effective photosynthesis. During the later phase of the 7-day treatment, however, chlorophyll content and photosynthetic efficiency decreased in the Co2+-treated daughter fronds, indicating that Co2+ inhibits the biosynthesis of chlorophyll rather than leading to the destruction of pre-existing pigment molecules. In addition, during the first 4 d of Co2+ treatment starch accumulated in the fronds and led to the transition of chloroplasts to chloro-amyloplasts and amylo-chloroplasts, while starch levels strongly decreased thereafter. (C) 2015 Elsevier Ltd. All rights reserved.
KW - Chloroplast
KW - Cobalt
KW - Lemnaceae
KW - Lemna minor
KW - Phytotoxicity
KW - Starch accumulation
Y1 - 2015
U6 - https://doi.org/10.1016/j.chemosphere.2015.03.008
SN - 0045-6535
SN - 1879-1298
VL - 131
SP - 149
EP - 156
PB - Elsevier
CY - Oxford
ER -
TY - JOUR
A1 - Diluiso, Francesca
A1 - Walk, Paula
A1 - Manych, Niccolo
A1 - Cerutti, Nicola
A1 - Chipiga, Vladislav
A1 - Workman, Annabelle
A1 - Ayas, Ceren
A1 - Cui, Ryna Yiyun
A1 - Cui, Diyang
A1 - Song, Kaihui
A1 - Banisch, Lucy A.
A1 - Moretti, Nikolaj
A1 - Callaghan, Max W.
A1 - Clarke, Leon
A1 - Creutzig, Felix
A1 - Hilaire, Jerome
A1 - Jotzo, Frank
A1 - Kalkuhl, Matthias
A1 - Lamb, William F.
A1 - Löschel, Andreas
A1 - Müller-Hansen, Finn
A1 - Nemet, Gregory F.
A1 - Oei, Pao-Yu
A1 - Sovacool, Benjamin K.
A1 - Steckel, Jan Christoph
A1 - Thomas, Sebastian
A1 - Wiseman, John
A1 - Minx, Jan C.
T1 - Coal transitions - part 1
BT - a systematic map and review of case study learnings from regional, national, and local coal phase-out experiences
JF - Environmental research letters
N2 - A rapid coal phase-out is needed to meet the goals of the Paris Agreement, but is hindered by serious challenges ranging from vested interests to the risks of social disruption. To understand how to organize a global coal phase-out, it is crucial to go beyond cost-effective climate mitigation scenarios and learn from the experience of previous coal transitions. Despite the relevance of the topic, evidence remains fragmented throughout different research fields, and not easily accessible. To address this gap, this paper provides a systematic map and comprehensive review of the literature on historical coal transitions. We use computer-assisted systematic mapping and review methods to chart and evaluate the available evidence on historical declines in coal production and consumption. We extracted a dataset of 278 case studies from 194 publications, covering coal transitions in 44 countries and ranging from the end of the 19th century until 2021. We find a relatively recent and rapidly expanding body of literature reflecting the growing importance of an early coal phase-out in scientific and political debates. Previous evidence has primarily focused on the United Kingdom, the United States, and Germany, while other countries that experienced large coal declines, like those in Eastern Europe, are strongly underrepresented. An increasing number of studies, mostly published in the last 5 years, has been focusing on China. Most of the countries successfully reducing coal dependency have undergone both demand-side and supply-side transitions. This supports the use of policy approaches targeting both demand and supply to achieve a complete coal phase-out. From a political economy perspective, our dataset highlights that most transitions are driven by rising production costs for coal, falling prices for alternative energies, or local environmental concerns, especially regarding air pollution. The main challenges for coal-dependent regions are structural change transformations, in particular for industry and labor. Rising unemployment is the most largely documented outcome in the sample. Policymakers at multiple levels are instrumental in facilitating coal transitions. They rely mainly on regulatory instruments to foster the transitions and compensation schemes or investment plans to deal with their transformative processes. Even though many models suggest that coal phase-outs are among the low-hanging fruits on the way to climate neutrality and meeting the international climate goals, our case studies analysis highlights the intricate political economy at work that needs to be addressed through well-designed and just policies.
KW - climate change mitigation
KW - coal transitions
KW - evidence synthesis
KW - political economy
KW - systematic map
Y1 - 2021
U6 - https://doi.org/10.1088/1748-9326/ac1b58
SN - 1748-9326
VL - 16
IS - 11
PB - Institute of Physics Publishing (IOP)
CY - Bristol
ER -
TY - JOUR
A1 - Filser, Matthias
A1 - Tiberius, Victor
A1 - Kraus, Sascha
A1 - Zeitlhofer, Tanita
A1 - Kailer, Norbert
A1 - Müller, Adrian
T1 - Opportunity recognition
BT - conversational foundations and pathways ahead
JF - Entrepreneurship research journal
N2 - This paper provides an overview of the ever-increasing literature on opportunity recognition, with a focus on its antecedents and determinants. With a two-step research approach, a bibliometric analysis and a systematic literature review, we structure the current research in this field. By using bibliometric techniques, we analyzed 161 publications and, consequently, clustered the 30 most influential references. Apart from economic theories and the role of opportunity recognition in entrepreneurship, a strong research focus is on antecedents of opportunity recognition. Therefore, in our subsequent literature review, we focus on determinants which influence opportunity recognition. We find that the opportunity recognition process is influenced by various personal, organizational and environmental factors. We conclude with a research outlook for future research opportunities on opportunity recognition.
KW - opportunity recognition
KW - bibliometric analysis
KW - systematic literature review
Y1 - 2020
U6 - https://doi.org/10.1515/erj-2020-0124
SN - 2194-6175
VL - 13
IS - 1
SP - 1
EP - 30
PB - De Gruyter
CY - Berlin
ER -
TY - GEN
A1 - Merks, Anne Margarete
A1 - Swinarski, Marie
A1 - Meyer, Alexander Matthias
A1 - Müller, Nicola Victoria
A1 - Özcan, Ismail
A1 - Donat, Stefan
A1 - Burger, Alexa
A1 - Gilbert, Stephen
A1 - Mosimann, Christian
A1 - Abdelilah-Seyfried, Salim
A1 - Panáková, Daniela
T1 - Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity
T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe
N2 - Development of a multiple-chambered heart from the linear heart tube is inherently linked to cardiac looping. Although many molecular factors regulating the process of cardiac chamber ballooning have been identified, the cellular mechanisms underlying the chamber formation remain unclear. Here, we demonstrate that cardiac chambers remodel by cell neighbour exchange of cardiomyocytes guided by the planar cell polarity (PCP) pathway triggered by two non-canonical Wnt ligands, Wnt5b and Wnt11. We find that PCP signalling coordinates the localisation of actomyosin activity, and thus the efficiency of cell neighbour exchange. On a tissue-scale, PCP signalling planar-polarises tissue tension by restricting the actomyosin contractility to the apical membranes of outflow tract cells. The tissue-scale polarisation of actomyosin contractility is required for cardiac looping that occurs concurrently with chamber ballooning. Taken together, our data reveal that instructive PCP signals couple cardiac chamber expansion with cardiac looping through the organ-scale polarisation of actomyosin-based tissue tension.
T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 849
KW - convergent extension
KW - branching morphogenesis
KW - actin cytoskeleton
KW - zebrafish heart
KW - mouse heart
KW - drosophila
KW - cadherin
KW - gene
KW - differentiation
KW - proliferation
Y1 - 2020
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-427026
SN - 1866-8372
IS - 849
ER -
TY - JOUR
A1 - Müller-Röber, Bernd
A1 - Zimmermann, Matthias
A1 - Eckardt, Barbara
A1 - Jäger, Heidi
A1 - Kampe, Heike
A1 - Horn-Conrad, Antje
A1 - Jäger, Sophie
T1 - Portal Wissen = Paths
BT - The Research Magazine of the University of Potsdam
N2 - How traits are inherited from one generation to the next, how mutations change genetic information and consequently contribute to the development of new characteristics and emergence of new species – all these are exciting biological questions. Over millions of years, genetic differentiation has brought about an incredible diversity of species. Evolution has followed many different paths. It has led to an awesome natural biodiversity – to organisms that have adapted to very different environments and are sometimes oddly shaped or behave strangely. Humanmade biodiversity is stunning, too. Just think of the 10,000 rose varieties whose beauty delights, or the myriad wheat, barley, and corn variations; plants that had all once been plain grasses feed us today. We humans create our own biodiversity unknown to nature. And it is serving us well.
Thanks to genome research we are now able to read the complete genetic information of organisms within a few hours or days. It takes much longer, however, to functionally map the many genomic sequences. Researchers achieve this through various methods: Activating or deactivating genes systematically, modifying their code, and exchanging genetic information between organisms have become standard procedures worldwide. The path to knowledge is often intricate, though. Elaborate experimental approaches are often necessary to gain insight into biological processes.
Methods of genomic research enable us to investigate not only what is “out there” in nature, but also to ask, “How does a living organism, like a moss, react when sent to the International Space Station (ISS)? Can we gain knowledge about the adaptation strategies of living beings in harsh environmental conditions or even for colonizing the Moon or Mars?” Can we use synthetic biology to precisely alter microorganisms, planned on a drawing board so to speak, to create new options for treating diseases or for making innovative biology-based products? The answer to both questions is a resounding Yes! (Although moving to other planets is not on our present agenda.) Human land use determines biodiversity. On the other hand, organisms influence the formation of landscapes and, sooner or later, the composition of our atmosphere. This also leads to exciting scientific questions. Researchers have to strike new paths to reach new conclusions. Paths often cross other paths. A few years ago it was still unforeseeable that ecological research would substantially benefit from fast DNA sequencing methods. Genome researchers could hardly assume that the same techniques would lead to new possibilities for examining the highly complex cellular regulation and optimizing biotechnological processes.
You will find examples of the multi-faceted research in biology as well as other very interesting articles in the latest edition of Portal Wissen. I wish you an enjoyable read!
Prof. Dr. Bernd Müller-Röber
Professor of Molecular Biology
T3 - Portal Wissen: The research magazine of the University of Potsdam [Englische Ausgabe] - 01/2015
Y1 - 2015
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-441506
SN - 2198-9974
IS - 01/2015
ER -
TY - BOOK
A1 - Thieken, Annegret
A1 - Bessel, Tina
A1 - Callsen, Ines
A1 - Falter, Daniela
A1 - Hasan, Issa
A1 - Kienzler, Sarah
A1 - Kox, Thomas
A1 - Kreibich, Heidi
A1 - Kuhlicke, Christian
A1 - Kunz, Michael
A1 - Matthias, Max
A1 - Meyer, Volker
A1 - Mühr, Bernhard
A1 - Müller, Meike
A1 - Otto, Antje
A1 - Pech, Ina
A1 - Petrow, Theresia
A1 - Pisi, Sebastian
A1 - Rother, Karl-Heinz
A1 - Schröter, Kai
T1 - Das Hochwasser im Juni 2013
BT - Bewährungsprobe für das Hochwasserrisikomanagement in Deutschland
T3 - Schriftenreihe des DKKV ; 53
Y1 - 2015
SN - 978-3-933181-62-6
PB - Deutsches Komitee Katastrophenvorsorge
CY - Bonn
ER -
TY - JOUR
A1 - Bapolisi, Alain Murhimalika
A1 - Kielb, Patrycja
A1 - Bekir, Marek
A1 - Lehnen, Anne-Catherine
A1 - Radon, Christin
A1 - Laroque, Sophie
A1 - Wendler, Petra
A1 - Müller-Werkmeister, Henrike
A1 - Hartlieb, Matthias
T1 - Antimicrobial polymers of linear and bottlebrush architecture
BT - Probing the membrane interaction and physicochemical properties
JF - Macromolecular rapid communications : publishing the newsletters of the European Polymer Federation
N2 - Polymeric antimicrobial peptide mimics are a promising alternative for the future management of the daunting problems associated with antimicrobial resistance. However, the development of successful antimicrobial polymers (APs) requires careful control of factors such as amphiphilic balance, molecular weight, dispersity, sequence, and architecture. While most of the earlier developed APs focus on random linear copolymers, the development of APs with advanced architectures proves to be more potent. It is recently developed multivalent bottlebrush APs with improved antibacterial and hemocompatibility profiles, outperforming their linear counterparts. Understanding the rationale behind the outstanding biological activity of these newly developed antimicrobials is vital to further improving their performance. This work investigates the physicochemical properties governing the differences in activity between linear and bottlebrush architectures using various spectroscopic and microscopic techniques. Linear copolymers are more solvated, thermo-responsive, and possess facial amphiphilicity resulting in random aggregations when interacting with liposomes mimicking Escheria coli membranes. The bottlebrush copolymers adopt a more stable secondary conformation in aqueous solution in comparison to linear copolymers, conferring rapid and more specific binding mechanism to membranes. The advantageous physicochemical properties of the bottlebrush topology seem to be a determinant factor in the activity of these promising APs.
KW - antimicrobial polymers
KW - bottlebrush copolymers
KW - liposomes
KW - membrane
KW - interactions
KW - quartz crystal microbalance
Y1 - 2022
U6 - https://doi.org/10.1002/marc.202200288
SN - 1521-3927
SN - 1022-1336
VL - 43
IS - 19
PB - Wiley-VCH
CY - Weinheim
ER -
TY - BOOK
A1 - Schwarzer, Ingo
A1 - Weiß-Saoumi, Said
A1 - Kittel, Roland
A1 - Friedrich, Tobias
A1 - Kaynak, Koraltan
A1 - Durak, Cemil
A1 - Isbarn, Andreas
A1 - Diestel, Jörg
A1 - Knittel, Jens
A1 - Franz, Marquart
A1 - Morra, Carlos
A1 - Stahnke, Susanne
A1 - Braband, Jens
A1 - Dittmann, Johannes
A1 - Griebel, Stephan
A1 - Krampf, Andreas
A1 - Link, Martin
A1 - Müller, Matthias
A1 - Radestock, Jens
A1 - Strub, Leo
A1 - Bleeke, Kai
A1 - Jehl, Leander
A1 - Kapitza, Rüdiger
A1 - Messadi, Ines
A1 - Schmidt, Stefan
A1 - Schwarz-Rüsch, Signe
A1 - Pirl, Lukas
A1 - Schmid, Robert
A1 - Friedenberger, Dirk
A1 - Beilharz, Jossekin Jakob
A1 - Boockmeyer, Arne
A1 - Polze, Andreas
A1 - Röhrig, Ralf
A1 - Schäbe, Hendrik
A1 - Thiermann, Ricky
T1 - RailChain
BT - Abschlussbericht
N2 - The RailChain project designed, implemented, and experimentally evaluated a juridical recorder that is based on a distributed consensus protocol. That juridical blockchain recorder has been realized as distributed ledger on board the advanced TrainLab (ICE-TD 605 017) of Deutsche Bahn.
For the project, a consortium consisting of DB Systel, Siemens, Siemens Mobility, the Hasso Plattner Institute for Digital Engineering, Technische Universität Braunschweig, TÜV Rheinland InterTraffic, and Spherity has been formed. These partners not only concentrated competencies in railway operation, computer science, regulation, and approval, but also combined experiences from industry, research from academia, and enthusiasm from startups.
Distributed ledger technologies (DLTs) define distributed databases and express a digital protocol for transactions between business partners without the need for a trusted intermediary. The implementation of a blockchain with real-time requirements for the local network of a railway system (e.g., interlocking or train) allows to log data in the distributed system verifiably in real-time. For this, railway-specific assumptions can be leveraged to make modifications to standard blockchains protocols.
EULYNX and OCORA (Open CCS On-board Reference Architecture) are parts of a future European reference architecture for control command and signalling (CCS, Reference CCS Architecture – RCA). Both architectural concepts outline heterogeneous IT systems with components from multiple manufacturers. Such systems introduce novel challenges for the approved and safety-relevant CCS of railways which were considered neither for road-side nor for on-board systems so far. Logging implementations, such as the common juridical recorder on vehicles, can no longer be realized as a central component of a single manufacturer. All centralized approaches are in question.
The research project RailChain is funded by the mFUND program and gives practical evidence that distributed consensus protocols are a proper means to immutably (for legal purposes) store state information of many system components from multiple manufacturers. The results of RailChain have been published, prototypically implemented, and experimentally evaluated in large-scale field tests on the advanced TrainLab. At the same time, the project showed how RailChain can be integrated into the road-side and on-board architecture given by OCORA and EULYNX.
Logged data can now be analysed sooner and also their trustworthiness is being increased. This enables, e.g., auditable predictive maintenance, because it is ensured that data is authentic and unmodified at any point in time.
N2 - Das Projekt RailChain hat einen verteilten Juridical Recorder entworfen, implementiert und experimentell evaluiert, der auf einem echtzeitfähigen verteilten Konsensprotokoll basiert. Dieser Juridical Blockchain Recorder wurde als distributed ledger an Bord des advanced TrainLabs der Deutschen Bahn (ICE-TD 605 017) umgesetzt.
Für das Projekt hat sich ein Konsortium aus DB Systel, Siemens, Siemens Mobility, dem Hasso-Plattner-Institut für Digital Engineering, der Technischen Universität Braunschweig, sowie TÜV Rheinland InterTraffic und Spherity formiert und dabei Kompetenzen aus den Bereichen Bahnbetrieb, Informatik und Zulassungswesen gebündelt. Die Partner kombinieren Erfahrungen aus der Industrie und die akademische Forschung mit der Aufbruchstimmung aus dem Start-Up-Umfeld.
Distributed-Ledger-Technologien (DLTs) definieren verteilte Datenbanken und stellen ein digitales Protokoll für Transaktionen zwischen Geschäftspartnern dar, ohne dass ein Mittelsmann beteiligt sein müsste. Die Implementierung einer Blockchain mit Echtzeitanforderungen für das lokale Netzwerk einer Eisenbahnanlage (z. B. Stellwerk oder Zug) erlaubt es, die im verteilten System entstehenden Daten nachweislich in Echtzeit zu protokollieren. Dabei können eisenbahnspezifische Randbedingungen ausgenutzt werden, um Standard-Blockchain-Protokolle anzupassen.
EULYNX und OCORA (Open CCS On-board Reference Architecture) sind Bestandteile einer zukünftigen europäischen Referenzarchitektur für das Leit- und Sicherungssystem (Reference CCS Architecture – RCA, Control Command and Signalling – CCS). Beide Architekturkonzepte skizzieren herstellerübergreifende, komponentenbasierende heterogene IT-Systeme. Solche Systeme bergen neue Herausforderungen, die bislang im Kontext der zugelassenen, sicherheitsrelevanten Leit- und Sicherungstechnik der Bahn weder strecken- noch fahrzeugseitig adressiert werden mussten. Logbuch-Implementierungen, wie der gängige Juridical Recorder auf Fahrzeugen, können nun nicht mehr als zentrale Systemkomponente eines einzelnen Herstellers umgesetzt werden. Alle zentralisierten Lösungsansätze sind in Frage gestellt.
Das mFUND-geförderte Forschungsprojekt erbringt den praktischen Nachweis, dass Zustandsinformationen über eine Vielzahl von Systemkomponenten herstellerübergreifend und gerichtsfest mittels verteilten Konsensprotokollen gespeichert werden können. Ergebnisse von RailChain wurden publiziert, prototypisch implementiert und in großen Feldtests auf dem advanced TrainLab experimentell evaluiert. Gleichzeitig wurde aufgezeigt, wie sich RailChain in den mit OCORA und EULYNX vorgegebenen fahrzeug- und streckenseitigen Architekturentwurf integrieren lässt.
Daten können dadurch zeitnaher ausgewertet werden und gleichzeitig wird ihre Vertrauenswürdigkeit erhöht. Dies ermöglicht u. a. nachvollziehbare zustandsorientierte Wartung, denn es kann jederzeit sichergestellt werden, dass die Daten authentisch sind und auch nicht verändert wurden.
T3 - Technische Berichte des Hasso-Plattner-Instituts für Digital Engineering an der Universität Potsdam - 152
KW - Distributed-Ledger-Technologie (DLT)
KW - juridical recording
KW - Konsensprotokolle
KW - consensus protocols
KW - Digitalisierung
KW - digitalization
KW - Bahnwesen
KW - railways
KW - Blockchain
KW - asset management
KW - selbstbestimmte Identitäten
KW - self-sovereign identity
KW - dezentrale Identitäten
KW - decentral identities
KW - überprüfbare Nachweise
KW - verifiable credentials
KW - Echtzeit
KW - real-time
KW - Standardisierung
KW - standardization
KW - Verlässlichkeit
KW - dependability
KW - Fehlertoleranz
KW - fault tolerance
Y1 - 2023
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-577409
SN - 978-3-86956-550-7
SN - 1613-5652
SN - 2191-1665
IS - 152
PB - Universitätsverlag Potsdam
CY - Potsdam
ER -
TY - JOUR
A1 - Gulbins, Anne
A1 - Schumacher, Fabian
A1 - Becker, Katrin Anne
A1 - Wilker, Barbara
A1 - Soddemann, Matthias
A1 - Boldrin, Francesco
A1 - Müller, Christian P.
A1 - Edwards, Michael J.
A1 - Goodman, Michael
A1 - Caldwell, Charles C.
A1 - Kleuser, Burkhard
A1 - Kornhuber, Johannes
A1 - Szabo, Ildiko
A1 - Gulbins, Erich
T1 - Antidepressants act by inducing autophagy controlled by sphingomyelin-ceramide
JF - Molecular psychiatry
N2 - Major depressive disorder (MDD) is a common and severe disease characterized by mood changes, somatic alterations, and often suicide. MDD is treated with antidepressants, but the molecular mechanism of their action is unknown. We found that widely used antidepressants such as amitriptyline and fluoxetine induce autophagy in hippocampal neurons via the slow accumulation of sphingomyelin in lysosomes and Golgi membranes and of ceramide in the endoplasmic reticulum (ER). ER ceramide stimulates phosphatase 2A and thereby the autophagy proteins Ulk, Beclin, Vps34/Phosphatidylinositol 3-kinase, p62, and Lc3B. Although treatment with amitriptyline or fluoxetine requires at least 12 days to achieve sphingomyelin accumulation and the subsequent biochemical and cellular changes, direct inhibition of sphingomyelin synthases with tricyclodecan-9-yl-xanthogenate (D609) results in rapid (within 3 days) accumulation of ceramide in the ER, activation of autophagy, and reversal of biochemical and behavioral signs of stress-induced MDD. Inhibition of Beclin blocks the antidepressive effects of amitriptyline and D609 and induces cellular and behavioral changes typical of MDD. These findings identify sphingolipid-controlled autophagy as an important target for antidepressive treatment methods and provide a rationale for the development of novel antidepressants that act within a few days.
Y1 - 2018
U6 - https://doi.org/10.1038/s41380-018-0090-9
SN - 1359-4184
SN - 1476-5578
VL - 23
IS - 12
SP - 2324
EP - 2346
PB - Nature Publ. Group
CY - London
ER -
TY - JOUR
A1 - Volk, Benno
A1 - Markert, Doreen
A1 - Riejok, Henriette
A1 - Dittberner, Jürgen
A1 - Wanka, Johanna
A1 - Wilkens, Martin
A1 - Görtemaker, Manfred
A1 - Regierer, Babette
A1 - Steup, Martin
A1 - Müller-Röber, Bernd
A1 - Wernicke, Matthias
A1 - Altenberger, Uwe
A1 - Stölting, Erhard
A1 - Ferý, Carolin
A1 - Egenter, Peter
A1 - Lenz, Claudia
A1 - Jakubowski, Zuzanna
A1 - Klötzer, Sylvia
A1 - Krause, Michael
A1 - Dietsch, Ulrich
T1 - Portal = Vor der Präsidenten-Wahl: Erwartungen, Wünsche, Vorschläge
BT - Die Potsdamer Universitätszeitung
N2 - Aus dem Inhalt:
- Vor der Präsidenten-Wahl: Erwartungen, Wünsche, Vorschläge
- Der AStA in der Krise?
- Über Satire und Macht in der DDR
- Vom Fünf-Sterne-Koch zum Mensaleiter
T3 - Portal: Das Potsdamer Universitätsmagazin - 04-05/2006
Y1 - 2006
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440005
SN - 1618-6893
IS - 04-05/2006
ER -
TY - BOOK
A1 - Olsen, Susan
A1 - Stiebels, Barbara
A1 - Bierwisch, Manfred
A1 - Zimmermann, Ilse
A1 - Cavar, Damir
A1 - Georgi, Doreen
A1 - Bacskai-Atkari, Julia
A1 - Alexiadou, Artemis
A1 - Błaszczak, Joanna
A1 - Müller, Gereon
A1 - Šimík, Radek
A1 - Meinunger, André
A1 - Thiersch, Craig
A1 - Arnhold, Anja
A1 - Féry, Caroline
A1 - Bayer, Josef
A1 - Titov, Elena
A1 - Fominyam, Henry
A1 - Tran, Thuan
A1 - Bornkessel-Schlesewsky, Ina D.
A1 - Schlesewsky, Matthias
A1 - Zimmermann, Malte
A1 - Häussler, Jana
A1 - Mucha, Anne
A1 - Schmidt, Andreas
A1 - Weskott, Thomas
A1 - Wierzba, Marta
A1 - Stede, Manfred
A1 - Skopeteas, Stavros
A1 - Gafos, Adamantios I.
A1 - Haider, Hubert
A1 - Wunderlich, Dieter
A1 - Staudacher, Peter
A1 - Rauh, Gisa
ED - Brown, Jessica M. M.
ED - Schmidt, Andreas
ED - Wierzba, Marta
T1 - Of Trees and Birds
BT - A Festschrift for Gisbert Fanselow
N2 - Gisbert Fanselow’s work has been invaluable and inspiring to many researchers working on syntax, morphology, and information structure, both from a theoretical and from an experimental perspective. This volume comprises a collection of articles dedicated to Gisbert on the occasion of his 60th birthday, covering a range of topics from these areas and beyond. The contributions have in common that in a broad sense they have to do with language structures (and thus trees), and that in a more specific sense they have to do with birds. They thus cover two of Gisbert’s major interests in- and outside of the linguistic world (and perhaps even at the interface).
KW - Festschrift
KW - Linguistik
KW - Syntax
KW - Morphologie
KW - Informationsstruktur
KW - festschrift
KW - linguistics
KW - syntax
KW - morphology
KW - information structure
Y1 - 2019
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-426542
SN - 978-3-86956-457-9
PB - Universitätsverlag Potsdam
CY - Potsdam
ER -
TY - JOUR
A1 - Christakoudi, Sofa
A1 - Tsilidis, Konstantinos K.
A1 - Muller, David C.
A1 - Freisling, Heinz
A1 - Weiderpass, Elisabete
A1 - Overvad, Kim
A1 - Söderberg, Stefan
A1 - Häggström, Christel
A1 - Pischon, Tobias
A1 - Dahm, Christina C.
A1 - Zhang, Jie
A1 - Tjønneland, Anne
A1 - Schulze, Matthias Bernd
T1 - A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort
JF - Scientific Reports
N2 - Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proportional hazards models adjusted for other risk factors. During a mean follow-up of 16.1 years, 38,178 participants died. Combining in one model BMI and a strongly correlated waist index altered the association patterns with mortality, to a predominantly negative association for BMI and a stronger positive association for the waist index, while combining BMI with the uncorrelated A Body Shape Index (ABSI) preserved the association patterns. Sex-specific cohort-wide quartiles of waist indices correlated with BMI could not separate high-risk from low-risk individuals within underweight (BMI<18.5 kg/m(2)) or obese (BMI30 kg/m(2)) categories, while the highest quartile of ABSI separated 18-39% of the individuals within each BMI category, which had 22-55% higher risk of death. In conclusion, only a waist index independent of BMI by design, such as ABSI, complements BMI and enables efficient risk stratification, which could facilitate personalisation of screening, treatment and monitoring.
KW - all-cause mortality
KW - anthropometric measures
KW - mass index
KW - overweight
KW - cancer
KW - prediction
KW - adiposity
KW - size
Y1 - 2020
VL - 10
IS - 1
PB - Springer Nature
CY - Berlin
ER -
TY - GEN
A1 - Christakoudi, Sofa
A1 - Tsilidis, Konstantinos K.
A1 - Muller, David C.
A1 - Freisling, Heinz
A1 - Weiderpass, Elisabete
A1 - Overvad, Kim
A1 - Söderberg, Stefan
A1 - Häggström, Christel
A1 - Pischon, Tobias
A1 - Dahm, Christina C.
A1 - Zhang, Jie
A1 - Tjønneland, Anne
A1 - Schulze, Matthias Bernd
T1 - A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort
T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2 - Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proportional hazards models adjusted for other risk factors. During a mean follow-up of 16.1 years, 38,178 participants died. Combining in one model BMI and a strongly correlated waist index altered the association patterns with mortality, to a predominantly negative association for BMI and a stronger positive association for the waist index, while combining BMI with the uncorrelated A Body Shape Index (ABSI) preserved the association patterns. Sex-specific cohort-wide quartiles of waist indices correlated with BMI could not separate high-risk from low-risk individuals within underweight (BMI<18.5 kg/m(2)) or obese (BMI30 kg/m(2)) categories, while the highest quartile of ABSI separated 18-39% of the individuals within each BMI category, which had 22-55% higher risk of death. In conclusion, only a waist index independent of BMI by design, such as ABSI, complements BMI and enables efficient risk stratification, which could facilitate personalisation of screening, treatment and monitoring.
T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1200
KW - all-cause mortality
KW - anthropometric measures
KW - mass index
KW - overweight
KW - cancer
KW - prediction
KW - adiposity
KW - size
Y1 - 2020
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-525827
SN - 1866-8372
IS - 1
ER -
TY - JOUR
A1 - Christakoudi, Sofia
A1 - Pagoni, Panagiota
A1 - Ferrari, Pietro
A1 - Cross, Amanda J.
A1 - Tzoulaki, Ioanna
A1 - Muller, David C.
A1 - Weiderpass, Elisabete
A1 - Freisling, Heinz
A1 - Murphy, Neil
A1 - Dossus, Laure
A1 - Turzanski Fortner, Renee
A1 - Agudo, Antonio
A1 - Overvad, Kim
A1 - Perez-Cornago, Aurora
A1 - Key, Timothy J.
A1 - Brennan, Paul
A1 - Johansson, Mattias
A1 - Tjonneland, Anne
A1 - Halkjaer, Jytte
A1 - Boutron-Ruault, Marie-Christine
A1 - Artaud, Fanny
A1 - Severi, Gianluca
A1 - Kaaks, Rudolf
A1 - Schulze, Matthias Bernd
A1 - Bergmann, Manuela M.
A1 - Masala, Giovanna
A1 - Grioni, Sara
A1 - Simeon, Vittorio
A1 - Tumino, Rosario
A1 - Sacerdote, Carlotta
A1 - Skeie, Guri
A1 - Rylander, Charlotta
A1 - Borch, Kristin Benjaminsen
A1 - Quiros, J. Ramon
A1 - Rodriguez-Barranco, Miguel
A1 - Chirlaque, Maria-Dolores
A1 - Ardanaz, Eva
A1 - Amiano, Pilar
A1 - Drake, Isabel
A1 - Stocks, Tanja
A1 - Häggström, Christel
A1 - Harlid, Sophia
A1 - Ellingjord-Dale, Merete
A1 - Riboli, Elio
A1 - Tsilidis, Konstantinos K.
T1 - Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
JF - International journal of cancer
N2 - Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) category during middle adulthood with 42 cancers, using multivariable Cox proportional hazards models in the European Prospective Investigation into Cancer and Nutrition cohort. Of 241 323 participants (31% men), 20% lost and 32% gained weight (>0.4 to 5.0 kg/year) during 6.9 years (average). During 8.0 years of follow-up after the second weight assessment, 20 960 incident cancers were ascertained. Independent of baseline BMI, weight gain (per one kg/year increment) was positively associated with cancer of the corpus uteri (hazard ratio [HR] = 1.14; 95% confidence interval: 1.05-1.23). Compared to stable weight (+/- 0.4 kg/year), weight gain (>0.4 to 5.0 kg/year) was positively associated with cancers of the gallbladder and bile ducts (HR = 1.41; 1.01-1.96), postmenopausal breast (HR = 1.08; 1.00-1.16) and thyroid (HR = 1.40; 1.04-1.90). Compared to maintaining normal weight, maintaining overweight or obese BMI (World Health Organisation categories) was positively associated with most obesity-related cancers. Compared to maintaining the baseline BMI category, weight gain to a higher BMI category was positively associated with cancers of the postmenopausal breast (HR = 1.19; 1.06-1.33), ovary (HR = 1.40; 1.04-1.91), corpus uteri (HR = 1.42; 1.06-1.91), kidney (HR = 1.80; 1.20-2.68) and pancreas in men (HR = 1.81; 1.11-2.95). Losing weight to a lower BMI category, however, was inversely associated with cancers of the corpus uteri (HR = 0.40; 0.23-0.69) and colon (HR = 0.69; 0.52-0.92). Our findings support avoiding weight gain and encouraging weight loss in middle adulthood.
KW - BMI change
KW - cancer
KW - middle adulthood
KW - weight gain
KW - weight loss
Y1 - 2020
U6 - https://doi.org/10.1002/ijc.33339
SN - 0020-7136
SN - 1097-0215
VL - 148
IS - 7
SP - 1637
EP - 1651
PB - Wiley
CY - Hoboken
ER -
TY - GEN
A1 - Christakoudi, Sofia
A1 - Pagoni, Panagiota
A1 - Ferrari, Pietro
A1 - Cross, Amanda J.
A1 - Tzoulaki, Ioanna
A1 - Muller, David C.
A1 - Weiderpass, Elisabete
A1 - Freisling, Heinz
A1 - Murphy, Neil
A1 - Dossus, Laure
A1 - Turzanski Fortner, Renee
A1 - Agudo, Antonio
A1 - Overvad, Kim
A1 - Perez-Cornago, Aurora
A1 - Key, Timothy J.
A1 - Brennan, Paul
A1 - Johansson, Mattias
A1 - Tjonneland, Anne
A1 - Halkjaer, Jytte
A1 - Boutron-Ruault, Marie-Christine
A1 - Artaud, Fanny
A1 - Severi, Gianluca
A1 - Kaaks, Rudolf
A1 - Schulze, Matthias Bernd
A1 - Bergmann, Manuela M.
A1 - Masala, Giovanna
A1 - Grioni, Sara
A1 - Simeon, Vittorio
A1 - Tumino, Rosario
A1 - Sacerdote, Carlotta
A1 - Skeie, Guri
A1 - Rylander, Charlotta
A1 - Borch, Kristin Benjaminsen
A1 - Quiros, J. Ramon
A1 - Rodriguez-Barranco, Miguel
A1 - Chirlaque, Maria-Dolores
A1 - Ardanaz, Eva
A1 - Amiano, Pilar
A1 - Drake, Isabel
A1 - Stocks, Tanja
A1 - Haggstrom, Christel
A1 - Harlid, Sophia
A1 - Ellingjord-Dale, Merete
A1 - Riboli, Elio
A1 - Tsilidis, Konstantinos K.
T1 - Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
T2 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2 - Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) category during middle adulthood with 42 cancers, using multivariable Cox proportional hazards models in the European Prospective Investigation into Cancer and Nutrition cohort. Of 241 323 participants (31% men), 20% lost and 32% gained weight (>0.4 to 5.0 kg/year) during 6.9 years (average). During 8.0 years of follow-up after the second weight assessment, 20 960 incident cancers were ascertained. Independent of baseline BMI, weight gain (per one kg/year increment) was positively associated with cancer of the corpus uteri (hazard ratio [HR] = 1.14; 95% confidence interval: 1.05-1.23). Compared to stable weight (+/- 0.4 kg/year), weight gain (>0.4 to 5.0 kg/year) was positively associated with cancers of the gallbladder and bile ducts (HR = 1.41; 1.01-1.96), postmenopausal breast (HR = 1.08; 1.00-1.16) and thyroid (HR = 1.40; 1.04-1.90). Compared to maintaining normal weight, maintaining overweight or obese BMI (World Health Organisation categories) was positively associated with most obesity-related cancers. Compared to maintaining the baseline BMI category, weight gain to a higher BMI category was positively associated with cancers of the postmenopausal breast (HR = 1.19; 1.06-1.33), ovary (HR = 1.40; 1.04-1.91), corpus uteri (HR = 1.42; 1.06-1.91), kidney (HR = 1.80; 1.20-2.68) and pancreas in men (HR = 1.81; 1.11-2.95). Losing weight to a lower BMI category, however, was inversely associated with cancers of the corpus uteri (HR = 0.40; 0.23-0.69) and colon (HR = 0.69; 0.52-0.92). Our findings support avoiding weight gain and encouraging weight loss in middle adulthood.
T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1373
KW - BMI change
KW - cancer
KW - middle adulthood
KW - weight gain
KW - weight loss
Y1 - 2020
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-573609
SN - 1866-8372
IS - 7
ER -
TY - JOUR
A1 - Schweppe, Robert
A1 - Thober, Stephan
A1 - Müller, Sebastian
A1 - Kelbling, Matthias
A1 - Kumar, Rohini
A1 - Attinger, Sabine
A1 - Samaniego, Luis
T1 - MPR 1.0: a stand-alone multiscale parameter regionalization tool for improved parameter estimation of land surface models
JF - Geoscientific model development : an interactive open access journal of the European Geosciences Union
N2 - Distributed environmental models such as land surface models (LSMs) require model parameters in each spatial modeling unit (e.g., grid cell), thereby leading to a high-dimensional parameter space. One approach to decrease the dimensionality of the parameter space in these models is to use regularization techniques. One such highly efficient technique is the multiscale parameter regionalization (MPR) framework that translates high-resolution predictor variables (e.g., soil textural properties) into model parameters (e.g., porosity) via transfer functions (TFs) and upscaling operators that are suitable for every modeled process. This framework yields seamless model parameters at multiple scales and locations in an effective manner. However, integration of MPR into existing modeling workflows has been hindered thus far by hard-coded configurations and non-modular software designs. For these reasons, we redesigned MPR as a model-agnostic, stand-alone tool. It is a useful software for creating graphs of NetCDF variables, wherein each node is a variable and the links consist of TFs and/or upscaling operators. In this study, we present and verify our tool against a previous version, which was implemented in the mesoscale hydrologic model (mHM; https://www.ufz.de/mhm, last access: 16 January 2022). By using this tool for the generation of continental-scale soil hydraulic parameters applicable to different models (Noah-MP and HTESSEL), we showcase its general functionality and flexibility. Further, using model parameters estimated by the MPR tool leads to significant changes in long-term estimates of evapotranspiration, as compared to their default parameterizations. For example, a change of up to 25 % in long-term evapotranspiration flux is observed in Noah-MP and HTESSEL in the Mississippi River basin. We postulate that use of the stand-alone MPR tool will considerably increase the transparency and reproducibility of the parameter estimation process in distributed (environmental) models. It will also allow a rigorous uncertainty estimation related to the errors of the predictors (e.g., soil texture fields), transfer function and its parameters, and remapping (or upscaling) algorithms.
Y1 - 2022
U6 - https://doi.org/10.5194/gmd-15-859-2022
SN - 1991-959X
SN - 1991-9603
VL - 15
IS - 2
SP - 859
EP - 882
PB - Copernicus
CY - Göttingen
ER -
TY - JOUR
A1 - Hildebrand, Viet
A1 - Heydenreich, Matthias
A1 - Laschewsky, Andre
A1 - Moeller, Heiko M.
A1 - Müller-Buschbaum, Peter
A1 - Papadakis, Christine M.
A1 - Schanzenbach, Dirk
A1 - Wischerhoff, Erik
T1 - "Schizophrenic" self-assembly of dual thermoresponsive block copolymers bearing a zwitterionic and a non-ionic hydrophilic block
JF - Polymer : the international journal for the science and technology of polymers
N2 - Several series of presumed dual thermo-responsive diblock copolymers consisting of one non-ionic and one zwitterionic block were synthesized via consecutive reversible addition-fragmentation chain transfer (RAFT) polymerization. For all copolymers, poly(N-isopropylmethacrylamide) was chosen as non-ionic block that shows a coil-to-globule collapse transition of the lower critical solution temperature (LCST) type. In contrast, the chemical structure of zwitterionic blocks, which all belonged to the class of poly(sulfobetaine methacrylate)s, was varied broadly, in order to tune their coil-to-globule collapse transition of the upper critical solution temperature (UCST) type. All polymers were labeled with a solvatochromic fluorescent end-group. The dual thermo-responsive behavior and the resulting multifarious temperature-dependent self-assembly in aqueous solution were mapped by temperature resolved turbidimetry, H-1 NMR spectroscopy, dynamic light scattering (DLS), and fluorescence spectroscopy. Depending on the relative positions between the UCST-type and LCST-type transition temperatures, as well as on the width of the window in-between, all the four possible modes of stimulus induced micellization can be realized. This includes classical induced micellization due to a transition from a double hydrophilic, or respectively, from a double hydrophobic to an amphiphilic state, as well as "schizophrenic" behavior, where the core- and shell-forming blocks are inverted. The exchange of the roles of the hydrophilic and hydrophobic block in the amphiphilic states is possible through a homogeneous intermediate state or a heterogeneous one. (C) 2017 Elsevier Ltd. All rights reserved.
KW - RAFT polymerization
KW - Block copolymer
KW - Sulfobetaine methacrylate
KW - Responsive polymer
KW - LCST
KW - UCST
KW - Schizophrenic self-assembly
Y1 - 2017
U6 - https://doi.org/10.1016/j.polymer.2017.06.063
SN - 0032-3861
SN - 1873-2291
VL - 122
SP - 347
EP - 357
PB - Elsevier
CY - Oxford
ER -
TY - JOUR
A1 - Zhong, Qi
A1 - Mi, Lei
A1 - Metwalli, Ezzeldin
A1 - Biessmann, Lorenz
A1 - Philipp, Martine
A1 - Miasnikova, Anna
A1 - Laschewsky, Andre
A1 - Papadakis, Christine M.
A1 - Cubitt, Robert
A1 - Schwartzkopf, Matthias
A1 - Roth, Stephan V.
A1 - Wang, Jiping
A1 - Müller-Buschbaum, Peter
T1 - Effect of chain architecture on the swelling and thermal response of star-shaped thermo-responsive (poly(methoxy diethylene glycol acrylate)-block-polystyrene)(3) block copolymer films
JF - Soft matter
N2 - The effect of chain architecture on the swelling and thermal response of thin films obtained from an amphiphilic three-arm star-shaped thermo-responsive block copolymer poly(methoxy diethylene glycol acrylate)-block-polystyrene ((PMDEGA-b-PS)(3)) is investigated by in situ neutron reflectivity (NR) measurements. The PMDEGA and PS blocks are micro-phase separated with randomly distributed PS nanodomains. The (PMDEGA-b-PS)(3) films show a transition temperature (TT) at 33 degrees C in white light interferometry. The swelling capability of the (PMDEGA-b-PS)(3) films in a D2O vapor atmosphere is better than that of films from linear PS-b-PMDEGA-b-PS triblock copolymers, which can be attributed to the hydrophilic end groups and limited size of the PS blocks in (PMDEGA-b-PS)(3). However, the swelling kinetics of the as-prepared (PMDEGA-b-PS)(3) films and the response of the swollen film to a temperature change above the TT are significantly slower than that in the PS-b-PMDEGA-b-PS films, which may be related to the conformation restriction by the star-shape. Unlike in the PS-b-PMDEGA-b-PS films, the amount of residual D2O in the collapsed (PMDEGA-b-PS)(3) films depends on the final temperature. It decreases from (9.7 +/- 0.3)% to (7.0 +/- 0.3)% or (6.0 +/- 0.3)% when the final temperatures are set to 35 degrees C, 45 degrees C and 50 degrees C, respectively. This temperature-dependent reduction of embedded D2O originates from the hindrance of chain conformation from the star-shaped chain architecture.
Y1 - 2018
U6 - https://doi.org/10.1039/c8sm00965a
SN - 1744-683X
SN - 1744-6848
VL - 14
IS - 31
SP - 6582
EP - 6594
PB - Royal Society of Chemistry
CY - Cambridge
ER -
TY - JOUR
A1 - Allan, Eric
A1 - Bossdorf, Oliver
A1 - Dormann, Carsten F.
A1 - Prati, Daniel
A1 - Gossner, Martin M.
A1 - Tscharntke, Teja
A1 - Blüthgen, Nico
A1 - Bellach, Michaela
A1 - Birkhofer, Klaus
A1 - Boch, Steffen
A1 - Böhm, Stefan
A1 - Börschig, Carmen
A1 - Chatzinotas, Antonis
A1 - Christ, Sabina
A1 - Daniel, Rolf
A1 - Diekötter, Tim
A1 - Fischer, Christiane
A1 - Friedl, Thomas
A1 - Glaser, Karin
A1 - Hallmann, Christine
A1 - Hodac, Ladislav
A1 - Hölzel, Norbert
A1 - Jung, Kirsten
A1 - Klein, Alexandra-Maria
A1 - Klaus, Valentin H.
A1 - Kleinebecker, Till
A1 - Krauss, Jochen
A1 - Lange, Markus
A1 - Morris, E. Kathryn
A1 - Müller, Jörg
A1 - Nacke, Heiko
A1 - Pasalic, Esther
A1 - Rillig, Matthias C.
A1 - Rothenwoehrer, Christoph
A1 - Schally, Peter
A1 - Scherber, Christoph
A1 - Schulze, Waltraud X.
A1 - Socher, Stephanie A.
A1 - Steckel, Juliane
A1 - Steffan-Dewenter, Ingolf
A1 - Türke, Manfred
A1 - Weiner, Christiane N.
A1 - Werner, Michael
A1 - Westphal, Catrin
A1 - Wolters, Volkmar
A1 - Wubet, Tesfaye
A1 - Gockel, Sonja
A1 - Gorke, Martin
A1 - Hemp, Andreas
A1 - Renner, Swen C.
A1 - Schöning, Ingo
A1 - Pfeiffer, Simone
A1 - König-Ries, Birgitta
A1 - Buscot, Francois
A1 - Linsenmair, Karl Eduard
A1 - Schulze, Ernst-Detlef
A1 - Weisser, Wolfgang W.
A1 - Fischer, Markus
T1 - Interannual variation in land-use intensity enhances grassland multidiversity
JF - Proceedings of the National Academy of Sciences of the United States of America
N2 - Although temporal heterogeneity is a well-accepted driver of biodiversity, effects of interannual variation in land-use intensity (LUI) have not been addressed yet. Additionally, responses to land use can differ greatly among different organisms; therefore, overall effects of land-use on total local biodiversity are hardly known. To test for effects of LUI (quantified as the combined intensity of fertilization, grazing, and mowing) and interannual variation in LUI (SD in LUI across time), we introduce a unique measure of whole-ecosystem biodiversity, multidiversity. This synthesizes individual diversity measures across up to 49 taxonomic groups of plants, animals, fungi, and bacteria from 150 grasslands. Multidiversity declined with increasing LUI among grasslands, particularly for rarer species and aboveground organisms, whereas common species and belowground groups were less sensitive. However, a high level of interannual variation in LUI increased overall multidiversity at low LUI and was even more beneficial for rarer species because it slowed the rate at which the multidiversity of rare species declined with increasing LUI. In more intensively managed grasslands, the diversity of rarer species was, on average, 18% of the maximum diversity across all grasslands when LUI was static over time but increased to 31% of the maximum when LUI changed maximally over time. In addition to decreasing overall LUI, we suggest varying LUI across years as a complementary strategy to promote biodiversity conservation.
KW - biodiversity loss
KW - agricultural grasslands
KW - Biodiversity Exploratories
Y1 - 2014
U6 - https://doi.org/10.1073/pnas.1312213111
SN - 0027-8424
VL - 111
IS - 1
SP - 308
EP - 313
PB - National Acad. of Sciences
CY - Washington
ER -
TY - JOUR
A1 - Abdalla, Hassan E.
A1 - Adam, R.
A1 - Aharonian, Felix A.
A1 - Benkhali, F. Ait
A1 - Angüner, Ekrem Oǧuzhan
A1 - Arakawa, M.
A1 - Arcaro, C.
A1 - Armand, C.
A1 - Ashkar, H.
A1 - Backes, M.
A1 - Martins, V. Barbosa
A1 - Barnard, M.
A1 - Becherini, Y.
A1 - Berge, D.
A1 - Bernloehr, K.
A1 - Bissaldi, E.
A1 - Blackwell, R.
A1 - Boettcher, M.
A1 - Boisson, C.
A1 - Bolmont, J.
A1 - Bonnefoy, S.
A1 - Bregeon, J.
A1 - Breuhaus, M.
A1 - Brun, F.
A1 - Brun, P.
A1 - Bryan, M.
A1 - Buechele, M.
A1 - Bulik, T.
A1 - Bylund, T.
A1 - Capasso, M.
A1 - Caroff, S.
A1 - Carosi, A.
A1 - Casanova, Sabrina
A1 - Cerruti, M.
A1 - Chand, T.
A1 - Chandra, S.
A1 - Chen, A.
A1 - Colafrancesco, S.
A1 - Curylo, M.
A1 - Davids, I. D.
A1 - Deil, C.
A1 - Devin, J.
A1 - deWilt, P.
A1 - Dirson, L.
A1 - Djannati-Atai, A.
A1 - Dmytriiev, A.
A1 - Donath, A.
A1 - Doroshenko, V
A1 - Dyks, J.
A1 - Egberts, Kathrin
A1 - Emery, G.
A1 - Ernenwein, J-P
A1 - Eschbach, S.
A1 - Feijen, K.
A1 - Fegan, S.
A1 - Fiasson, A.
A1 - Fontaine, G.
A1 - Funk, S.
A1 - Fussling, Matthias
A1 - Gabici, S.
A1 - Gallant, Y. A.
A1 - Gate, F.
A1 - Giavitto, G.
A1 - Giunti, L.
A1 - Glawion, D.
A1 - Glicenstein, J. F.
A1 - Gottschall, D.
A1 - Grondin, M-H
A1 - Hahn, J.
A1 - Haupt, M.
A1 - Heinzelmann, G.
A1 - Henri, G.
A1 - Hermann, G.
A1 - Hinton, J. A.
A1 - Hofmann, W.
A1 - Hoischen, Clemens
A1 - Holch, T. L.
A1 - Holler, M.
A1 - Horns, D.
A1 - Huber, D.
A1 - Iwasaki, H.
A1 - Jamrozy, M.
A1 - Jankowsky, D.
A1 - Jankowsky, F.
A1 - Jardin-Blicq, A.
A1 - Jung-Richardt, I
A1 - Kastendieck, M. A.
A1 - Katarzynski, K.
A1 - Katsuragawa, M.
A1 - Katz, U.
A1 - Khangulyan, D.
A1 - Khelifi, B.
A1 - King, J.
A1 - Klepser, S.
A1 - Kluzniak, W.
A1 - Komin, Nu
A1 - Kosack, K.
A1 - Kostunin, D.
A1 - Kreter, M.
A1 - Lamanna, G.
A1 - Lemiere, A.
A1 - Lemoine-Goumard, M.
A1 - Lenain, J-P
A1 - Leser, Eva
A1 - Levy, C.
A1 - Lohse, T.
A1 - Lypova, I
A1 - Mackey, J.
A1 - Majumdar, J.
A1 - Malyshev, D.
A1 - Marandon, V
A1 - Marcowith, Alexandre
A1 - Mares, A.
A1 - Mariaud, C.
A1 - Marti-Devesa, G.
A1 - Marx, R.
A1 - Maurin, G.
A1 - Meintjes, P. J.
A1 - Mitchell, A. M. W.
A1 - Moderski, R.
A1 - Mohamed, M.
A1 - Mohrmann, L.
A1 - Moore, C.
A1 - Moulin, Emmanuel
A1 - Muller, J.
A1 - Murach, T.
A1 - Nakashima, S.
A1 - de Naurois, M.
A1 - Ndiyavala, H.
A1 - Niederwanger, F.
A1 - Niemiec, J.
A1 - Oakes, L.
A1 - Odaka, H.
A1 - Ohm, S.
A1 - Wilhelmi, E. de Ona
A1 - Ostrowski, M.
A1 - Oya, I
A1 - Panter, M.
A1 - Parsons, R. D.
A1 - Perennes, C.
A1 - Petrucci, P-O
A1 - Peyaud, B.
A1 - Piel, Q.
A1 - Pita, S.
A1 - Poireau, V
A1 - Noel, A. Priyana
A1 - Prokhorov, D. A.
A1 - Prokoph, H.
A1 - Puehlhofer, G.
A1 - Punch, M.
A1 - Quirrenbach, A.
A1 - Raab, S.
A1 - Rauth, R.
A1 - Reimer, A.
A1 - Reimer, O.
A1 - Remy, Q.
A1 - Renaud, M.
A1 - Rieger, F.
A1 - Rinchiuso, L.
A1 - Romoli, C.
A1 - Rowell, G.
A1 - Rudak, B.
A1 - Ruiz-Velasco, E.
A1 - Sahakian, V
A1 - Sailer, S.
A1 - Saito, S.
A1 - Sanchez, D. A.
A1 - Santangelo, Andrea
A1 - Sasaki, M.
A1 - Schlickeiser, R.
A1 - Schussler, F.
A1 - Schulz, A.
A1 - Schutte, H. M.
A1 - Schwanke, U.
A1 - Schwemmer, S.
A1 - Seglar-Arroyo, M.
A1 - Senniappan, M.
A1 - Seyffert, A. S.
A1 - Shafi, N.
A1 - Shiningayamwe, K.
A1 - Simoni, R.
A1 - Sinha, A.
A1 - Sol, H.
A1 - Specovius, A.
A1 - Spir-Jacob, M.
A1 - Stawarz, L.
A1 - Steenkamp, R.
A1 - Stegmann, Christian
A1 - Steppa, Constantin Beverly
A1 - Takahashi, T.
A1 - Tavernier, T.
A1 - Taylor, A. M.
A1 - Terrier, R.
A1 - Tiziani, D.
A1 - Tluczykont, M.
A1 - Trichard, C.
A1 - Tsirou, M.
A1 - Tsuji, N.
A1 - Tuffs, R.
A1 - Uchiyama, Y.
A1 - van der Walt, D. J.
A1 - van Eldik, C.
A1 - van Rensburg, C.
A1 - van Soelen, B.
A1 - Vasileiadis, G.
A1 - Veh, J.
A1 - Venter, C.
A1 - Vincent, P.
A1 - Vink, J.
A1 - Voelk, H. J.
A1 - Vuillaume, T.
A1 - Wadiasingh, Z.
A1 - Wagner, S. J.
A1 - White, R.
A1 - Wierzcholska, A.
A1 - Yang, R.
A1 - Yoneda, H.
A1 - Zacharias, M.
A1 - Zanin, R.
A1 - Zdziarski, A. A.
A1 - Zech, Alraune
A1 - Ziegler, A.
A1 - Zorn, J.
A1 - Zywucka, N.
A1 - de Palma, F.
A1 - Axelsson, M.
A1 - Roberts, O. J.
T1 - A very-high-energy component deep in the gamma-ray burst afterglow
JF - Nature : the international weekly journal of science
N2 - Gamma-ray bursts (GRBs) are brief flashes of gamma-rays and are considered to be the most energetic explosive phenomena in the Universe(1). The emission from GRBs comprises a short (typically tens of seconds) and bright prompt emission, followed by a much longer afterglow phase. During the afterglow phase, the shocked outflow-produced by the interaction between the ejected matter and the circumburst medium-slows down, and a gradual decrease in brightness is observed(2). GRBs typically emit most of their energy via.-rays with energies in the kiloelectronvolt-to-megaelectronvolt range, but a few photons with energies of tens of gigaelectronvolts have been detected by space-based instruments(3). However, the origins of such high-energy (above one gigaelectronvolt) photons and the presence of very-high-energy (more than 100 gigaelectronvolts) emission have remained elusive(4). Here we report observations of very-high-energy emission in the bright GRB 180720B deep in the GRB afterglow-ten hours after the end of the prompt emission phase, when the X-ray flux had already decayed by four orders of magnitude. Two possible explanations exist for the observed radiation: inverse Compton emission and synchrotron emission of ultrarelativistic electrons. Our observations show that the energy fluxes in the X-ray and gamma-ray range and their photon indices remain comparable to each other throughout the afterglow. This discovery places distinct constraints on the GRB environment for both emission mechanisms, with the inverse Compton explanation alleviating the particle energy requirements for the emission observed at late times. The late timing of this detection has consequences for the future observations of GRBs at the highest energies.
Y1 - 2019
U6 - https://doi.org/10.1038/s41586-019-1743-9
SN - 0028-0836
SN - 1476-4687
VL - 575
IS - 7783
SP - 464
EP - +
PB - Nature Publ. Group
CY - London
ER -
TY - JOUR
A1 - Abdalla, H.
A1 - Adam, R.
A1 - Aharonian, Felix A.
A1 - Benkhali, F. Ait
A1 - Angüner, Ekrem Oǧuzhan
A1 - Arcaro, C.
A1 - Armand, C.
A1 - Armstrong, T.
A1 - Ashkar, H.
A1 - Backes, M.
A1 - Baghmanyan, V.
A1 - Martins, V. Barbosa
A1 - Barnacka, A.
A1 - Barnard, M.
A1 - Becherini, Y.
A1 - Berge, D.
A1 - Bernlohr, K.
A1 - Bi, B.
A1 - Bottcher, M.
A1 - Boisson, C.
A1 - Bolmont, J.
A1 - de Lavergne, M. de Bony
A1 - Bordas, Pol
A1 - Breuhaus, M.
A1 - Brun, F.
A1 - Brun, P.
A1 - Bryan, M.
A1 - Buchele, M.
A1 - Bulik, T.
A1 - Bylund, T.
A1 - Caroff, S.
A1 - Carosi, A.
A1 - Casanova, Sabrina
A1 - Chand, T.
A1 - Chandra, S.
A1 - Chen, A.
A1 - Cotter, G.
A1 - Curylo, M.
A1 - Mbarubucyeye, J. Damascene
A1 - Davids, I. D.
A1 - Davies, J.
A1 - Deil, C.
A1 - Devin, J.
A1 - deWilt, P.
A1 - Dirson, L.
A1 - Djannati-Atai, A.
A1 - Dmytriiev, A.
A1 - Donath, A.
A1 - Doroshenko, V.
A1 - Duffy, C.
A1 - Dyks, J.
A1 - Egberts, Kathrin
A1 - Eichhorn, F.
A1 - Einecke, S.
A1 - Emery, G.
A1 - Ernenwein, J. -P.
A1 - Feijen, K.
A1 - Fegan, S.
A1 - Fiasson, A.
A1 - de Clairfontaine, G. Fichet
A1 - Fontaine, G.
A1 - Funk, S.
A1 - Fussling, Matthias
A1 - Gabici, S.
A1 - Gallant, Y. A.
A1 - Giavitto, G.
A1 - Giunti, L.
A1 - Glawion, D.
A1 - Glicenstein, J. F.
A1 - Gottschall, D.
A1 - Grondin, M. -H.
A1 - Hahn, J.
A1 - Haupt, M.
A1 - Hermann, G.
A1 - Hinton, J. A.
A1 - Hofmann, W.
A1 - Hoischen, Clemens
A1 - Holch, T. L.
A1 - Holler, M.
A1 - Horbe, M.
A1 - Horns, D.
A1 - Huber, D.
A1 - Jamrozy, M.
A1 - Jankowsky, D.
A1 - Jankowsky, F.
A1 - Jardin-Blicq, A.
A1 - Joshi, V.
A1 - Jung-Richardt, I.
A1 - Kasai, E.
A1 - Kastendieck, M. A.
A1 - Katarzynski, K.
A1 - Katz, U.
A1 - Khangulyan, D.
A1 - Khelifi, B.
A1 - Klepser, S.
A1 - Kluzniak, W.
A1 - Komin, Nu.
A1 - Konno, R.
A1 - Kosack, K.
A1 - Kostunin, D.
A1 - Kreter, M.
A1 - Lamanna, G.
A1 - Lemiere, A.
A1 - Lemoine-Goumard, M.
A1 - Lenain, J. -P.
A1 - Levy, C.
A1 - Lohse, T.
A1 - Lypova, I.
A1 - Mackey, J.
A1 - Majumdar, J.
A1 - Malyshev, D.
A1 - Malyshev, D.
A1 - Marandon, V.
A1 - Marchegiani, P.
A1 - Marcowith, Alexandre
A1 - Mares, A.
A1 - Marti-Devesa, G.
A1 - Marx, R.
A1 - Maurin, G.
A1 - Meintjes, P. J.
A1 - Meyer, M.
A1 - Mitchell, A.
A1 - Moderski, R.
A1 - Mohamed, M.
A1 - Mohrmann, L.
A1 - Montanari, A.
A1 - Moore, C.
A1 - Morris, P.
A1 - Moulin, Emmanuel
A1 - Muller, J.
A1 - Murach, T.
A1 - Nakashima, K.
A1 - Nayerhoda, A.
A1 - de Naurois, M.
A1 - Ndiyavala, H.
A1 - Niederwanger, F.
A1 - Niemiec, J.
A1 - Oakes, L.
A1 - O'Brien, Patrick
A1 - Odaka, H.
A1 - Ohm, S.
A1 - Olivera-Nieto, L.
A1 - Wilhelmi, E. de Ona
A1 - Ostrowski, M.
A1 - Oya, I.
A1 - Panter, M.
A1 - Panny, S.
A1 - Parsons, R. D.
A1 - Peron, G.
A1 - Peyaud, B.
A1 - Piel, Q.
A1 - Pita, S.
A1 - Poireau, V.
A1 - Noel, A. Priyana
A1 - Prokhorov, D. A.
A1 - Prokoph, H.
A1 - Puhlhofer, G.
A1 - Punch, M.
A1 - Quirrenbach, A.
A1 - Raab, S.
A1 - Rauth, R.
A1 - Reichherzer, P.
A1 - Reimer, A.
A1 - Reimer, O.
A1 - Remy, Q.
A1 - Renaud, M.
A1 - Rieger, F.
A1 - Rinchiuso, L.
A1 - Romoli, C.
A1 - Rowell, G.
A1 - Rudak, B.
A1 - Ruiz-Velasco, E.
A1 - Sahakian, V.
A1 - Sailer, S.
A1 - Sanchez, D. A.
A1 - Santangelo, Andrea
A1 - Sasaki, M.
A1 - Scalici, M.
A1 - Schussler, F.
A1 - Schutte, H. M.
A1 - Schwanke, U.
A1 - Schwemmer, S.
A1 - Seglar-Arroyo, M.
A1 - Senniappan, M.
A1 - Seyffert, A. S.
A1 - Shafi, N.
A1 - Shiningayamwe, K.
A1 - Simoni, R.
A1 - Sinha, A.
A1 - Sol, H.
A1 - Specovius, A.
A1 - Spencer, S.
A1 - Spir-Jacob, M.
A1 - Stawarz, L.
A1 - Sun, L.
A1 - Steenkamp, R.
A1 - Stegmann, C.
A1 - Steinmassl, S.
A1 - Steppa, C.
A1 - Takahashi, T.
A1 - Tavernier, T.
A1 - Taylor, A. M.
A1 - Terrier, R.
A1 - Tiziani, D.
A1 - Tluczykont, M.
A1 - Tomankova, L.
A1 - Trichard, C.
A1 - Tsirou, M.
A1 - Tuffs, R.
A1 - Uchiyama, Y.
A1 - van der Walt, D. J.
A1 - van Eldik, C.
A1 - van Rensburg, C.
A1 - van Soelen, B.
A1 - Vasileiadis, G.
A1 - Veh, J.
A1 - Venter, C.
A1 - Vincent, P.
A1 - Vink, J.
A1 - Volk, H. J.
A1 - Vuillaume, T.
A1 - Wadiasingh, Z.
A1 - Wagner, S. J.
A1 - Watson, J.
A1 - Werner, F.
A1 - White, R.
A1 - Wierzcholska, A.
A1 - Wong, Yu Wun
A1 - Yusafzai, A.
A1 - Zacharias, M.
A1 - Zanin, R.
A1 - Zargaryan, D.
A1 - Zdziarski, A. A.
A1 - Zech, Alraune
A1 - Zhu, S. J.
A1 - Ziegler, A.
A1 - Zorn, J.
A1 - Zouari, S.
A1 - Zywucka, N.
T1 - An extreme particle accelerator in the Galactic plane
BT - HESS J1826-130
JF - Astronomy and astrophysics : an international weekly journal
N2 - The unidentified very-high-energy (VHE; E > 0.1 TeV) gamma -ray source, HESS J1826-130, was discovered with the High Energy Stereoscopic System (HESS) in the Galactic plane. The analysis of 215 h of HESS data has revealed a steady gamma -ray flux from HESS J1826-130, which appears extended with a half-width of 0.21 degrees +/- 0.02
(stat)degrees
stat degrees +/- 0.05
(sys)degrees sys degrees . The source spectrum is best fit with either a power-law function with a spectral index Gamma = 1.78 +/- 0.10(stat) +/- 0.20(sys) and an exponential cut-off at 15.2
(+5.5)(-3.2) -3.2+5.5 TeV, or a broken power-law with Gamma (1) = 1.96 +/- 0.06(stat) +/- 0.20(sys), Gamma (2) = 3.59 +/- 0.69(stat) +/- 0.20(sys) for energies below and above E-br = 11.2 +/- 2.7 TeV, respectively. The VHE flux from HESS J1826-130 is contaminated by the extended emission of the bright, nearby pulsar wind nebula, HESS J1825-137, particularly at the low end of the energy spectrum. Leptonic scenarios for the origin of HESS J1826-130 VHE emission related to PSR J1826-1256 are confronted by our spectral and morphological analysis. In a hadronic framework, taking into account the properties of dense gas regions surrounding HESS J1826-130, the source spectrum would imply an astrophysical object capable of accelerating the parent particle population up to greater than or similar to 200 TeV. Our results are also discussed in a multiwavelength context, accounting for both the presence of nearby supernova remnants, molecular clouds, and counterparts detected in radio, X-rays, and TeV energies.
KW - ISM: supernova remnants
KW - ISM: clouds
KW - gamma rays: general
KW - gamma rays:
KW - ISM
Y1 - 2020
U6 - https://doi.org/10.1051/0004-6361/202038851
SN - 0004-6361
SN - 1432-0746
VL - 644
PB - EDP Sciences
CY - Les Ulis
ER -
TY - JOUR
A1 - Abdalla, Hassan E.
A1 - Adam, R.
A1 - Aharonian, Felix A.
A1 - Benkhali, F. Ait
A1 - Angüner, Ekrem Oǧuzhan
A1 - Arakawa, M.
A1 - Arcaro, C.
A1 - Armand, C.
A1 - Ashkar, H.
A1 - Backes, M.
A1 - Martins, V. Barbosa
A1 - Barnard, M.
A1 - Becherini, Y.
A1 - Berge, D.
A1 - Bernloehr, K.
A1 - Blackwell, R.
A1 - Böttcher, M.
A1 - Boisson, C.
A1 - Bolmont, J.
A1 - Bonnefoy, S.
A1 - Bregeon, J.
A1 - Breuhaus, M.
A1 - Brun, F.
A1 - Brun, P.
A1 - Bryan, M.
A1 - Büchele, M.
A1 - Bulik, T.
A1 - Bylund, T.
A1 - Capasso, M.
A1 - Caroff, S.
A1 - Carosi, A.
A1 - Casanova, Sabrina
A1 - Cerruti, M.
A1 - Chand, T.
A1 - Chandra, S.
A1 - Chen, A.
A1 - Colafrancesco, S.
A1 - Curylo, M.
A1 - Davids, I. D.
A1 - Deil, C.
A1 - Devin, J.
A1 - DeWilt, P.
A1 - Dirson, L.
A1 - Djannati-Ata, A.
A1 - Dmytriiev, A.
A1 - Donath, A.
A1 - Doroshenko, V
A1 - Dyks, J.
A1 - Egberts, Kathrin
A1 - Emery, G.
A1 - Ernenwein, J-P
A1 - Eschbach, S.
A1 - Feijen, K.
A1 - Fegan, S.
A1 - Fiasson, A.
A1 - Fontaine, G.
A1 - Funk, S.
A1 - Füßling, Matthias
A1 - Gabici, S.
A1 - Gallant, Y. A.
A1 - Gate, F.
A1 - Giavitto, G.
A1 - Glawion, D.
A1 - Glicenstein, J. F.
A1 - Gottschall, D.
A1 - Grondin, M-H
A1 - Hahn, J.
A1 - Haupt, M.
A1 - Heinzelmann, G.
A1 - Henri, G.
A1 - Hermann, G.
A1 - Hinton, James Anthony
A1 - Hofmann, W.
A1 - Hoischen, Clemens
A1 - Holch, Tim Lukas
A1 - Holler, M.
A1 - Horns, D.
A1 - Huber, D.
A1 - Iwasaki, H.
A1 - Jamrozy, M.
A1 - Jankowsky, D.
A1 - Jankowsky, F.
A1 - Jardin-Blicq, A.
A1 - Jung-Richardt, I
A1 - Kastendieck, M. A.
A1 - Katarzynski, K.
A1 - Katsuragawa, M.
A1 - Katz, U.
A1 - Khangulyan, D.
A1 - Khelifi, B.
A1 - King, J.
A1 - Klepser, S.
A1 - Kluzniak, W.
A1 - Komin, Nu
A1 - Kosack, K.
A1 - Kostunin, D.
A1 - Kraus, M.
A1 - Lamanna, G.
A1 - Lau, J.
A1 - Lemiere, A.
A1 - Lemoine-Goumard, M.
A1 - Lenain, J-P
A1 - Leser, Eva
A1 - Levy, C.
A1 - Lohse, T.
A1 - Lypova, I
A1 - Mackey, J.
A1 - Majumdar, J.
A1 - Malyshev, D.
A1 - Marandon, V
A1 - Marcowith, Alexandre
A1 - Mares, A.
A1 - Mariaud, C.
A1 - Marti-Devesa, G.
A1 - Marx, R.
A1 - Maurin, G.
A1 - Meintjes, P. J.
A1 - Mitchell, A. M. W.
A1 - Moderski, R.
A1 - Mohamed, M.
A1 - Mohrmann, L.
A1 - Moore, C.
A1 - Moulin, Emmanuel
A1 - Muller, J.
A1 - Murach, T.
A1 - Nakashima, S.
A1 - de Naurois, M.
A1 - Ndiyavala, H.
A1 - Niederwanger, F.
A1 - Niemiec, J.
A1 - Oakes, L.
A1 - Odaka, H.
A1 - Ohm, S.
A1 - Wilhelmi, E. de Ona
A1 - Ostrowski, M.
A1 - Oya, I
A1 - Panter, M.
A1 - Parsons, R. D.
A1 - Perennes, C.
A1 - Petrucci, P-O
A1 - Peyaud, B.
A1 - Piel, Q.
A1 - Pita, S.
A1 - Poireau, V
A1 - Priyana Noel, A.
A1 - Prokhorov, D. A.
A1 - Prokoph, H.
A1 - Pühlhofer, G.
A1 - Punch, M.
A1 - Quirrenbach, A.
A1 - Raab, S.
A1 - Rauth, R.
A1 - Reimer, A.
A1 - Reimer, O.
A1 - Remy, Q.
A1 - Renaud, M.
A1 - Rieger, F.
A1 - Rinchiuso, L.
A1 - Romoli, C.
A1 - Rowell, G.
A1 - Rudak, B.
A1 - Ruiz-Velasco, E.
A1 - Sahakian, V
A1 - Saito, S.
A1 - Sanchez, David M.
A1 - Santangelo, Andrea
A1 - Sasaki, M.
A1 - Schlickeiser, R.
A1 - Schüssler, F.
A1 - Schulz, A.
A1 - Schutte, H.
A1 - Schwanke, U.
A1 - Schwemmer, S.
A1 - Seglar-Arroyo, M.
A1 - Senniappan, M.
A1 - Seyffert, A. S.
A1 - Shafi, N.
A1 - Shiningayamwe, K.
A1 - Simoni, R.
A1 - Sinha, A.
A1 - Sol, H.
A1 - Specovius, A.
A1 - Spir-Jacob, M.
A1 - Stawarz, L.
A1 - Steenkamp, R.
A1 - Stegmann, Christian
A1 - Steppa, Constantin Beverly
A1 - Takahashi, T.
A1 - Tavernier, T.
A1 - Taylor, A. M.
A1 - Terrier, R.
A1 - Tiziani, D.
A1 - Tluczykont, M.
A1 - Trichard, C.
A1 - Tsirou, M.
A1 - Tsuji, N.
A1 - Tuffs, R.
A1 - Uchiyama, Y.
A1 - van Der Walt, D. J.
A1 - van Eldik, C.
A1 - van Rensburg, C.
A1 - van Soelen, B.
A1 - Vasileiadis, G.
A1 - Veh, J.
A1 - Venter, C.
A1 - Vincent, P.
A1 - Vink, J.
A1 - Voisin, F.
A1 - Voelk, H. J.
A1 - Vuillaume, T.
A1 - Wadiasingh, Z.
A1 - Wagner, S. J.
A1 - White, R.
A1 - Wierzcholska, A.
A1 - Yang, R.
A1 - Yoneda, H.
A1 - Zacharias, Michael
A1 - Zanin, R.
A1 - Zdziarski, A. A.
A1 - Zech, Alraune
A1 - Ziegler, A.
A1 - Zorn, J.
A1 - Zywucka, N.
A1 - Meyer, M.
T1 - Constraints on the emission region of 3C 279 during strong flares in 2014 and 2015 through VHE gamma-ray observations with HESS
JF - Astronomy and astrophysics : an international weekly journal
N2 - The flat spectrum radio quasar 3C 279 is known to exhibit pronounced variability in the high-energy (100MeV < E < 100 GeV) gamma-ray band, which is continuously monitored with Fermi-LAT. During two periods of high activity in April 2014 and June 2015 target-of-opportunity observations were undertaken with the High Energy Stereoscopic System (H.E.S.S.) in the very-high-energy (VHE, E > 100 GeV) gamma-ray domain. While the observation in 2014 provides an upper limit, the observation in 2015 results in a signal with 8 : 7 sigma significance above an energy threshold of 66 GeV. No VHE variability was detected during the 2015 observations. The VHE photon spectrum is soft and described by a power-law index of 4.2 +/- 0.3. The H.E.S.S. data along with a detailed and contemporaneous multiwavelength data set provide constraints on the physical parameters of the emission region. The minimum distance of the emission region from the central black hole was estimated using two plausible geometries of the broad-line region and three potential intrinsic spectra. The emission region is confidently placed at r greater than or similar to 1 : 7 X 1017 cm from the black hole, that is beyond the assumed distance of the broad-line region. Time-dependent leptonic and lepto-hadronic one-zone models were used to describe the evolution of the 2015 flare. Neither model can fully reproduce the observations, despite testing various parameter sets. Furthermore, the H.E.S.S. data were used to derive constraints on Lorentz invariance violation given the large redshift of 3C 279.
KW - radiation mechanisms: non-thermal
KW - quasars: individual: 3C 279
KW - galaxies: active
KW - relativistic processes
Y1 - 2019
U6 - https://doi.org/10.1051/0004-6361/201935704
SN - 1432-0746
VL - 627
PB - EDP Sciences
CY - Les Ulis
ER -