TY - JOUR A1 - Wuttke, Matthias A1 - Li, Yong A1 - Li, Man A1 - Sieber, Karsten B. A1 - Feitosa, Mary F. A1 - Gorski, Mathias A1 - Tin, Adrienne A1 - Wang, Lihua A1 - Chu, Audrey Y. A1 - Hoppmann, Anselm A1 - Kirsten, Holger A1 - Giri, Ayush A1 - Chai, Jin-Fang A1 - Sveinbjornsson, Gardar A1 - Tayo, Bamidele O. A1 - Nutile, Teresa A1 - Fuchsberger, Christian A1 - Marten, Jonathan A1 - Cocca, Massimiliano A1 - Ghasemi, Sahar A1 - Xu, Yizhe A1 - Horn, Katrin A1 - Noce, Damia A1 - Van der Most, Peter J. A1 - Sedaghat, Sanaz A1 - Yu, Zhi A1 - Akiyama, Masato A1 - Afaq, Saima A1 - Ahluwalia, Tarunveer Singh A1 - Almgren, Peter A1 - Amin, Najaf A1 - Arnlov, Johan A1 - Bakker, Stephan J. L. A1 - Bansal, Nisha A1 - Baptista, Daniela A1 - Bergmann, Sven A1 - Biggs, Mary L. A1 - Biino, Ginevra A1 - Boehnke, Michael A1 - Boerwinkle, Eric A1 - Boissel, Mathilde A1 - Böttinger, Erwin A1 - Boutin, Thibaud S. A1 - Brenner, Hermann A1 - Brumat, Marco A1 - Burkhardt, Ralph A1 - Butterworth, Adam S. A1 - Campana, Eric A1 - Campbell, Archie A1 - Campbell, Harry A1 - Canouil, Mickael A1 - Carroll, Robert J. A1 - Catamo, Eulalia A1 - Chambers, John C. A1 - Chee, Miao-Ling A1 - Chee, Miao-Li A1 - Chen, Xu A1 - Cheng, Ching-Yu A1 - Cheng, Yurong A1 - Christensen, Kaare A1 - Cifkova, Renata A1 - Ciullo, Marina A1 - Concas, Maria Pina A1 - Cook, James P. A1 - Coresh, Josef A1 - Corre, Tanguy A1 - Sala, Cinzia Felicita A1 - Cusi, Daniele A1 - Danesh, John A1 - Daw, E. Warwick A1 - De Borst, Martin H. A1 - De Grandi, Alessandro A1 - De Mutsert, Renee A1 - De Vries, Aiko P. J. A1 - Degenhardt, Frauke A1 - Delgado, Graciela A1 - Demirkan, Ayse A1 - Di Angelantonio, Emanuele A1 - Dittrich, Katalin A1 - Divers, Jasmin A1 - Dorajoo, Rajkumar A1 - Eckardt, Kai-Uwe A1 - Ehret, Georg A1 - Elliott, Paul A1 - Endlich, Karlhans A1 - Evans, Michele K. A1 - Felix, Janine F. A1 - Foo, Valencia Hui Xian A1 - Franco, Oscar H. A1 - Franke, Andre A1 - Freedman, Barry I. A1 - Freitag-Wolf, Sandra A1 - Friedlander, Yechiel A1 - Froguel, Philippe A1 - Gansevoort, Ron T. A1 - Gao, He A1 - Gasparini, Paolo A1 - Gaziano, J. Michael A1 - Giedraitis, Vilmantas A1 - Gieger, Christian A1 - Girotto, Giorgia A1 - Giulianini, Franco A1 - Gogele, Martin A1 - Gordon, Scott D. A1 - Gudbjartsson, Daniel F. A1 - Gudnason, Vilmundur A1 - Haller, Toomas A1 - Hamet, Pavel A1 - Harris, Tamara B. A1 - Hartman, Catharina A. A1 - Hayward, Caroline A1 - Hellwege, Jacklyn N. A1 - Heng, Chew-Kiat A1 - Hicks, Andrew A. A1 - Hofer, Edith A1 - Huang, Wei A1 - Hutri-Kahonen, Nina A1 - Hwang, Shih-Jen A1 - Ikram, M. Arfan A1 - Indridason, Olafur S. A1 - Ingelsson, Erik A1 - Ising, Marcus A1 - Jaddoe, Vincent W. V. A1 - Jakobsdottir, Johanna A1 - Jonas, Jost B. A1 - Joshi, Peter K. A1 - Josyula, Navya Shilpa A1 - Jung, Bettina A1 - Kahonen, Mika A1 - Kamatani, Yoichiro A1 - Kammerer, Candace M. A1 - Kanai, Masahiro A1 - Kastarinen, Mika A1 - Kerr, Shona M. A1 - Khor, Chiea-Chuen A1 - Kiess, Wieland A1 - Kleber, Marcus E. A1 - Koenig, Wolfgang A1 - Kooner, Jaspal S. A1 - Korner, Antje A1 - Kovacs, Peter A1 - Kraja, Aldi T. A1 - Krajcoviechova, Alena A1 - Kramer, Holly A1 - Kramer, Bernhard K. A1 - Kronenberg, Florian A1 - Kubo, Michiaki A1 - Kuhnel, Brigitte A1 - Kuokkanen, Mikko A1 - Kuusisto, Johanna A1 - La Bianca, Martina A1 - Laakso, Markku A1 - Lange, Leslie A. A1 - Langefeld, Carl D. A1 - Lee, Jeannette Jen-Mai A1 - Lehne, Benjamin A1 - Lehtimaki, Terho A1 - Lieb, Wolfgang A1 - Lim, Su-Chi A1 - Lind, Lars A1 - Lindgren, Cecilia M. A1 - Liu, Jun A1 - Liu, Jianjun A1 - Loeffler, Markus A1 - Loos, Ruth J. F. A1 - Lucae, Susanne A1 - Lukas, Mary Ann A1 - Lyytikainen, Leo-Pekka A1 - Magi, Reedik A1 - Magnusson, Patrik K. E. A1 - Mahajan, Anubha A1 - Martin, Nicholas G. A1 - Martins, Jade A1 - Marz, Winfried A1 - Mascalzoni, Deborah A1 - Matsuda, Koichi A1 - Meisinger, Christa A1 - Meitinger, Thomas A1 - Melander, Olle A1 - Metspalu, Andres A1 - Mikaelsdottir, Evgenia K. A1 - Milaneschi, Yuri A1 - Miliku, Kozeta A1 - Mishra, Pashupati P. A1 - Program, V. A. Million Veteran A1 - Mohlke, Karen L. A1 - Mononen, Nina A1 - Montgomery, Grant W. A1 - Mook-Kanamori, Dennis O. A1 - Mychaleckyj, Josyf C. A1 - Nadkarni, Girish N. A1 - Nalls, Mike A. A1 - Nauck, Matthias A1 - Nikus, Kjell A1 - Ning, Boting A1 - Nolte, Ilja M. A1 - Noordam, Raymond A1 - Olafsson, Isleifur A1 - Oldehinkel, Albertine J. A1 - Orho-Melander, Marju A1 - Ouwehand, Willem H. A1 - Padmanabhan, Sandosh A1 - Palmer, Nicholette D. A1 - Palsson, Runolfur A1 - Penninx, Brenda W. J. H. A1 - Perls, Thomas A1 - Perola, Markus A1 - Pirastu, Mario A1 - Pirastu, Nicola A1 - Pistis, Giorgio A1 - Podgornaia, Anna I. A1 - Polasek, Ozren A1 - Ponte, Belen A1 - Porteous, David J. A1 - Poulain, Tanja A1 - Pramstaller, Peter P. A1 - Preuss, Michael H. A1 - Prins, Bram P. A1 - Province, Michael A. A1 - Rabelink, Ton J. A1 - Raffield, Laura M. A1 - Raitakari, Olli T. A1 - Reilly, Dermot F. A1 - Rettig, Rainer A1 - Rheinberger, Myriam A1 - Rice, Kenneth M. A1 - Ridker, Paul M. A1 - Rivadeneira, Fernando A1 - Rizzi, Federica A1 - Roberts, David J. A1 - Robino, Antonietta A1 - Rossing, Peter A1 - Rudan, Igor A1 - Rueedi, Rico A1 - Ruggiero, Daniela A1 - Ryan, Kathleen A. A1 - Saba, Yasaman A1 - Sabanayagam, Charumathi A1 - Salomaa, Veikko A1 - Salvi, Erika A1 - Saum, Kai-Uwe A1 - Schmidt, Helena A1 - Schmidt, Reinhold A1 - Ben Schottker, A1 - Schulz, Christina-Alexandra A1 - Schupf, Nicole A1 - Shaffer, Christian M. A1 - Shi, Yuan A1 - Smith, Albert V. A1 - Smith, Blair H. A1 - Soranzo, Nicole A1 - Spracklen, Cassandra N. A1 - Strauch, Konstantin A1 - Stringham, Heather M. A1 - Stumvoll, Michael A1 - Svensson, Per O. A1 - Szymczak, Silke A1 - Tai, E-Shyong A1 - Tajuddin, Salman M. A1 - Tan, Nicholas Y. Q. A1 - Taylor, Kent D. A1 - Teren, Andrej A1 - Tham, Yih-Chung A1 - Thiery, Joachim A1 - Thio, Chris H. L. A1 - Thomsen, Hauke A1 - Thorleifsson, Gudmar A1 - Toniolo, Daniela A1 - Tonjes, Anke A1 - Tremblay, Johanne A1 - Tzoulaki, Ioanna A1 - Uitterlinden, Andre G. A1 - Vaccargiu, Simona A1 - Van Dam, Rob M. A1 - Van der Harst, Pim A1 - Van Duijn, Cornelia M. A1 - Edward, Digna R. Velez A1 - Verweij, Niek A1 - Vogelezang, Suzanne A1 - Volker, Uwe A1 - Vollenweider, Peter A1 - Waeber, Gerard A1 - Waldenberger, Melanie A1 - Wallentin, Lars A1 - Wang, Ya Xing A1 - Wang, Chaolong A1 - Waterworth, Dawn M. A1 - Bin Wei, Wen A1 - White, Harvey A1 - Whitfield, John B. A1 - Wild, Sarah H. A1 - Wilson, James F. A1 - Wojczynski, Mary K. A1 - Wong, Charlene A1 - Wong, Tien-Yin A1 - Xu, Liang A1 - Yang, Qiong A1 - Yasuda, Masayuki A1 - Yerges-Armstrong, Laura M. A1 - Zhang, Weihua A1 - Zonderman, Alan B. A1 - Rotter, Jerome I. A1 - Bochud, Murielle A1 - Psaty, Bruce M. A1 - Vitart, Veronique A1 - Wilson, James G. A1 - Dehghan, Abbas A1 - Parsa, Afshin A1 - Chasman, Daniel I. A1 - Ho, Kevin A1 - Morris, Andrew P. A1 - Devuyst, Olivier A1 - Akilesh, Shreeram A1 - Pendergrass, Sarah A. A1 - Sim, Xueling A1 - Boger, Carsten A. A1 - Okada, Yukinori A1 - Edwards, Todd L. A1 - Snieder, Harold A1 - Stefansson, Kari A1 - Hung, Adriana M. A1 - Heid, Iris M. A1 - Scholz, Markus A1 - Teumer, Alexander A1 - Kottgen, Anna A1 - Pattaro, Cristian T1 - A catalog of genetic loci associated with kidney function from analyses of a million individuals JF - Nature genetics N2 - Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these,147 were likely to be relevant for kidney function on the basis of associations with the alternative kidney function marker blood urea nitrogen (n = 416,178). Pathway and enrichment analyses, including mouse models with renal phenotypes, support the kidney as the main target organ. A genetic risk score for lower eGFR was associated with clinically diagnosed CKD in 452,264 independent individuals. Colocalization analyses of associations with eGFR among 783,978 European-ancestry individuals and gene expression across 46 human tissues, including tubulo-interstitial and glomerular kidney compartments, identified 17 genes differentially expressed in kidney. Fine-mapping highlighted missense driver variants in 11 genes and kidney-specific regulatory variants. These results provide a comprehensive priority list of molecular targets for translational research. Y1 - 2019 U6 - https://doi.org/10.1038/s41588-019-0407-x SN - 1061-4036 SN - 1546-1718 VL - 51 IS - 6 SP - 957 EP - + PB - Nature Publ. Group CY - New York ER - TY - JOUR A1 - Tucker, Marlee A. A1 - Boehning-Gaese, Katrin A1 - Fagan, William F. A1 - Fryxell, John M. A1 - Van Moorter, Bram A1 - Alberts, Susan C. A1 - Ali, Abdullahi H. A1 - Allen, Andrew M. A1 - Attias, Nina A1 - Avgar, Tal A1 - Bartlam-Brooks, Hattie A1 - Bayarbaatar, Buuveibaatar A1 - Belant, Jerrold L. A1 - Bertassoni, Alessandra A1 - Beyer, Dean A1 - Bidner, Laura A1 - van Beest, Floris M. A1 - Blake, Stephen A1 - Blaum, Niels A1 - Bracis, Chloe A1 - Brown, Danielle A1 - de Bruyn, P. J. Nico A1 - Cagnacci, Francesca A1 - Calabrese, Justin M. A1 - Camilo-Alves, Constanca A1 - Chamaille-Jammes, Simon A1 - Chiaradia, Andre A1 - Davidson, Sarah C. A1 - Dennis, Todd A1 - DeStefano, Stephen A1 - Diefenbach, Duane A1 - Douglas-Hamilton, Iain A1 - Fennessy, Julian A1 - Fichtel, Claudia A1 - Fiedler, Wolfgang A1 - Fischer, Christina A1 - Fischhoff, Ilya A1 - Fleming, Christen H. A1 - Ford, Adam T. A1 - Fritz, Susanne A. A1 - Gehr, Benedikt A1 - Goheen, Jacob R. A1 - Gurarie, Eliezer A1 - Hebblewhite, Mark A1 - Heurich, Marco A1 - Hewison, A. J. Mark A1 - Hof, Christian A1 - Hurme, Edward A1 - Isbell, Lynne A. A1 - Janssen, Rene A1 - Jeltsch, Florian A1 - Kaczensky, Petra A1 - Kane, Adam A1 - Kappeler, Peter M. A1 - Kauffman, Matthew A1 - Kays, Roland A1 - Kimuyu, Duncan A1 - Koch, Flavia A1 - Kranstauber, Bart A1 - LaPoint, Scott A1 - Leimgruber, Peter A1 - Linnell, John D. C. A1 - Lopez-Lopez, Pascual A1 - Markham, A. Catherine A1 - Mattisson, Jenny A1 - Medici, Emilia Patricia A1 - Mellone, Ugo A1 - Merrill, Evelyn A1 - Mourao, Guilherme de Miranda A1 - Morato, Ronaldo G. A1 - Morellet, Nicolas A1 - Morrison, Thomas A. A1 - Diaz-Munoz, Samuel L. A1 - Mysterud, Atle A1 - Nandintsetseg, Dejid A1 - Nathan, Ran A1 - Niamir, Aidin A1 - Odden, John A1 - Oliveira-Santos, Luiz Gustavo R. A1 - Olson, Kirk A. A1 - Patterson, Bruce D. A1 - de Paula, Rogerio Cunha A1 - Pedrotti, Luca A1 - Reineking, Bjorn A1 - Rimmler, Martin A1 - Rogers, Tracey L. A1 - Rolandsen, Christer Moe A1 - Rosenberry, Christopher S. A1 - Rubenstein, Daniel I. A1 - Safi, Kamran A1 - Said, Sonia A1 - Sapir, Nir A1 - Sawyer, Hall A1 - Schmidt, Niels Martin A1 - Selva, Nuria A1 - Sergiel, Agnieszka A1 - Shiilegdamba, Enkhtuvshin A1 - Silva, Joao Paulo A1 - Singh, Navinder A1 - Solberg, Erling J. A1 - Spiegel, Orr A1 - Strand, Olav A1 - Sundaresan, Siva A1 - Ullmann, Wiebke A1 - Voigt, Ulrich A1 - Wall, Jake A1 - Wattles, David A1 - Wikelski, Martin A1 - Wilmers, Christopher C. A1 - Wilson, John W. A1 - Wittemyer, George A1 - Zieba, Filip A1 - Zwijacz-Kozica, Tomasz A1 - Mueller, Thomas T1 - Moving in the Anthropocene BT - global reductions in terrestrial mammalian movements JF - Science N2 - Animal movement is fundamental for ecosystem functioning and species survival, yet the effects of the anthropogenic footprint on animal movements have not been estimated across species. Using a unique GPS-tracking database of 803 individuals across 57 species, we found that movements of mammals in areas with a comparatively high human footprint were on average one-half to one-third the extent of their movements in areas with a low human footprint. We attribute this reduction to behavioral changes of individual animals and to the exclusion of species with long-range movements from areas with higher human impact. Global loss of vagility alters a key ecological trait of animals that affects not only population persistence but also ecosystem processes such as predator-prey interactions, nutrient cycling, and disease transmission. Y1 - 2018 U6 - https://doi.org/10.1126/science.aam9712 SN - 0036-8075 SN - 1095-9203 VL - 359 IS - 6374 SP - 466 EP - 469 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Yenesew, Abiy A1 - Twinomuhwezi, Hannington A1 - Kiremire, Bernard T. A1 - Mbugua, Martin N. A1 - Gitu, Peter M. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - 8-Methoxyneorautenol and radical scavenging flavonoids from Erythrina abyssinica N2 - A new pterocarpan (named 8-methoxyneorautenol) was isolated from the acetone ext. of the root bark of Erythrina abyssinica. In addn., the known isoflavonoid derivs. eryvarin L, erycristagallin and shinpterocarpin were identified for the first time from the roots of this plant. The structures were detd. on the basis of spectroscopic evidence. The new compd. showed selective antimicrobial activity against Trichophyton mentagrophytes. The acetone ext. of the root bark of E. abyssinica showed radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl radical (DPPH). The pterocarpenes, 3-hydroxy-9-methoxy-10-(3,3-dimethylallyl)pterocarpene and erycristagallin, were the most active constituents of the roots of this plant and showing dose-dependent activities similar to that of the std. quercetin. [on SciFinder (R)] Y1 - 2009 UR - http://www.ajol.info/journal_index.php?jid=120&ab=bcse SN - 1011-3924 ER - TY - JOUR A1 - Penone, Caterina A1 - Allan, Eric A1 - Soliveres, Santiago A1 - Felipe-Lucia, Maria R. A1 - Gossner, Martin M. A1 - Seibold, Sebastian A1 - Simons, Nadja K. A1 - Schall, Peter A1 - van der Plas, Fons A1 - Manning, Peter A1 - Manzanedo, Ruben D. A1 - Boch, Steffen A1 - Prati, Daniel A1 - Ammer, Christian A1 - Bauhus, Juergen A1 - Buscot, Francois A1 - Ehbrecht, Martin A1 - Goldmann, Kezia A1 - Jung, Kirsten A1 - Mueller, Joerg A1 - Mueller, Joerg C. A1 - Pena, Rodica A1 - Polle, Andrea A1 - Renner, Swen C. A1 - Ruess, Liliane A1 - Schoenig, Ingo A1 - Schrumpf, Marion A1 - Solly, Emily F. A1 - Tschapka, Marco A1 - Weisser, Wolfgang W. A1 - Wubet, Tesfaye A1 - Fischer, Markus T1 - Specialisation and diversity of multiple trophic groups are promoted by different forest features JF - Ecology letters N2 - While forest management strongly influences biodiversity, it remains unclear how the structural and compositional changes caused by management affect different community dimensions (e.g. richness, specialisation, abundance or completeness) and how this differs between taxa. We assessed the effects of nine forest features (representing stand structure, heterogeneity and tree composition) on thirteen above- and belowground trophic groups of plants, animals, fungi and bacteria in 150 temperate forest plots differing in their management type. Canopy cover decreased light resources, which increased community specialisation but reduced overall diversity and abundance. Features increasing resource types and diversifying microhabitats (admixing of oaks and conifers) were important and mostly affected richness. Belowground groups responded differently to those aboveground and had weaker responses to most forest features. Our results show that we need to consider forest features rather than broad management types and highlight the importance of considering several groups and community dimensions to better inform conservation. KW - biodiversity exploratories KW - dark diversity KW - forest management KW - global change KW - land-use KW - multidiversity KW - specialisation KW - temperate forests Y1 - 2018 U6 - https://doi.org/10.1111/ele.13182 SN - 1461-023X SN - 1461-0248 VL - 22 IS - 1 SP - 170 EP - 180 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Neumann, Bernhard A1 - Horstkemper, Marianne A1 - Krüger, Wolfgang A1 - Wilkens, Martin A1 - Bohlen, Andreas A1 - Frübing, Peter A1 - Wegener, Michael A1 - Scheff, Ullrich A1 - Neher, Dieter A1 - Brehmer, Ludwig A1 - Kleinpeter, Erich A1 - Wolf, Gunter A1 - Koetz, Joachim A1 - Peter, Martin G. A1 - Senkbeil, Sigrid A1 - Meyer, Till T1 - Portal = Im Trend: Physiker und Chemiker erforschen "Soft Matter" BT - Die Potsdamer Universitätszeitung N2 - Aus dem Inhalt: Im Trend: Physiker und Chemiker erforschen „Soft Matter“ -Brandenburger Netzwerk für Existenzgründer erhält Förderung -Universität leistet Beitrag zum Romantik-Jahr -Musiksender MTV und Bryan Adams auf dem Campus T3 - Portal: Das Potsdamer Universitätsmagazin - 06/2002 Y1 - 2002 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-501441 SN - 1618-6893 VL - 2002 ER - TY - JOUR A1 - Middeldorp, Christel M. A1 - Mahajan, Anubha A1 - Horikoshi, Momoko A1 - Robertson, Neil R. A1 - Beaumont, Robin N. A1 - Bradfield, Jonathan P. A1 - Bustamante, Mariona A1 - Cousminer, Diana L. A1 - Day, Felix R. A1 - De Silva, N. Maneka A1 - Guxens, Monica A1 - Mook-Kanamori, Dennis O. A1 - St Pourcain, Beate A1 - Warrington, Nicole M. A1 - Adair, Linda S. A1 - Ahlqvist, Emma A1 - Ahluwalia, Tarunveer Singh A1 - Almgren, Peter A1 - Ang, Wei A1 - Atalay, Mustafa A1 - Auvinen, Juha A1 - Bartels, Meike A1 - Beckmann, Jacques S. A1 - Bilbao, Jose Ramon A1 - Bond, Tom A1 - Borja, Judith B. A1 - Cavadino, Alana A1 - Charoen, Pimphen A1 - Chen, Zhanghua A1 - Coin, Lachlan A1 - Cooper, Cyrus A1 - Curtin, John A. A1 - Custovic, Adnan A1 - Das, Shikta A1 - Davies, Gareth E. A1 - Dedoussis, George V. A1 - Duijts, Liesbeth A1 - Eastwood, Peter R. A1 - Eliasen, Anders U. A1 - Elliott, Paul A1 - Eriksson, Johan G. A1 - Estivill, Xavier A1 - Fadista, Joao A1 - Fedko, Iryna O. A1 - Frayling, Timothy M. A1 - Gaillard, Romy A1 - Gauderman, W. James A1 - Geller, Frank A1 - Gilliland, Frank A1 - Gilsanz, Vincente A1 - Granell, Raquel A1 - Grarup, Niels A1 - Groop, Leif A1 - Hadley, Dexter A1 - Hakonarson, Hakon A1 - Hansen, Torben A1 - Hartman, Catharina A. A1 - Hattersley, Andrew T. A1 - Hayes, M. Geoffrey A1 - Hebebrand, Johannes A1 - Heinrich, Joachim A1 - Helgeland, Oyvind A1 - Henders, Anjali K. A1 - Henderson, John A1 - Henriksen, Tine B. A1 - Hirschhorn, Joel N. A1 - Hivert, Marie-France A1 - Hocher, Berthold A1 - Holloway, John W. A1 - Holt, Patrick A1 - Hottenga, Jouke-Jan A1 - Hypponen, Elina A1 - Iniguez, Carmen A1 - Johansson, Stefan A1 - Jugessur, Astanand A1 - Kahonen, Mika A1 - Kalkwarf, Heidi J. A1 - Kaprio, Jaakko A1 - Karhunen, Ville A1 - Kemp, John P. A1 - Kerkhof, Marjan A1 - Koppelman, Gerard H. A1 - Korner, Antje A1 - Kotecha, Sailesh A1 - Kreiner-Moller, Eskil A1 - Kulohoma, Benard A1 - Kumar, Ashish A1 - Kutalik, Zoltan A1 - Lahti, Jari A1 - Lappe, Joan M. A1 - Larsson, Henrik A1 - Lehtimaki, Terho A1 - Lewin, Alexandra M. A1 - Li, Jin A1 - Lichtenstein, Paul A1 - Lindgren, Cecilia M. A1 - Lindi, Virpi A1 - Linneberg, Allan A1 - Liu, Xueping A1 - Liu, Jun A1 - Lowe, William L. A1 - Lundstrom, Sebastian A1 - Lyytikainen, Leo-Pekka A1 - Ma, Ronald C. W. A1 - Mace, Aurelien A1 - Magi, Reedik A1 - Magnus, Per A1 - Mamun, Abdullah A. A1 - Mannikko, Minna A1 - Martin, Nicholas G. A1 - Mbarek, Hamdi A1 - McCarthy, Nina S. A1 - Medland, Sarah E. A1 - Melbye, Mads A1 - Melen, Erik A1 - Mohlke, Karen L. A1 - Monnereau, Claire A1 - Morgen, Camilla S. A1 - Morris, Andrew P. A1 - Murray, Jeffrey C. A1 - Myhre, Ronny A1 - Najman, Jackob M. A1 - Nivard, Michel G. A1 - Nohr, Ellen A. A1 - Nolte, Ilja M. A1 - Ntalla, Ioanna A1 - Oberfield, Sharon E. A1 - Oken, Emily A1 - Oldehinkel, Albertine J. A1 - Pahkala, Katja A1 - Palviainen, Teemu A1 - Panoutsopoulou, Kalliope A1 - Pedersen, Oluf A1 - Pennell, Craig E. A1 - Pershagen, Goran A1 - Pitkanen, Niina A1 - Plomin, Robert A1 - Power, Christine A1 - Prasad, Rashmi B. A1 - Prokopenko, Inga A1 - Pulkkinen, Lea A1 - Raikkonen, Katri A1 - Raitakari, Olli T. A1 - Reynolds, Rebecca M. A1 - Richmond, Rebecca C. A1 - Rivadeneira, Fernando A1 - Rodriguez, Alina A1 - Rose, Richard J. A1 - Salem, Rany A1 - Santa-Marina, Loreto A1 - Saw, Seang-Mei A1 - Schnurr, Theresia M. A1 - Scott, James G. A1 - Selzam, Saskia A1 - Shepherd, John A. A1 - Simpson, Angela A1 - Skotte, Line A1 - Sleiman, Patrick M. A. A1 - Snieder, Harold A1 - Sorensen, Thorkild I. A. A1 - Standl, Marie A1 - Steegers, Eric A. P. A1 - Strachan, David P. A1 - Straker, Leon A1 - Strandberg, Timo A1 - Taylor, Michelle A1 - Teo, Yik-Ying A1 - Thiering, Elisabeth A1 - Torrent, Maties A1 - Tyrrell, Jessica A1 - Uitterlinden, Andre G. A1 - van Beijsterveldt, Toos A1 - van der Most, Peter J. A1 - van Duijn, Cornelia M. A1 - Viikari, Jorma A1 - Vilor-Tejedor, Natalia A1 - Vogelezang, Suzanne A1 - Vonk, Judith M. A1 - Vrijkotte, Tanja G. M. A1 - Vuoksimaa, Eero A1 - Wang, Carol A. A1 - Watkins, William J. A1 - Wichmann, H-Erich A1 - Willemsen, Gonneke A1 - Williams, Gail M. A1 - Wilson, James F. A1 - Wray, Naomi R. A1 - Xu, Shujing A1 - Xu, Cheng-Jian A1 - Yaghootkar, Hanieh A1 - Yi, Lu A1 - Zafarmand, Mohammad Hadi A1 - Zeggini, Eleftheria A1 - Zemel, Babette S. A1 - Hinney, Anke A1 - Lakka, Timo A. A1 - Whitehouse, Andrew J. O. A1 - Sunyer, Jordi A1 - Widen, Elisabeth E. A1 - Feenstra, Bjarke A1 - Sebert, Sylvain A1 - Jacobsson, Bo A1 - Njolstad, Pal R. A1 - Stoltenberg, Camilla A1 - Smith, George Davey A1 - Lawlor, Debbie A. A1 - Paternoster, Lavinia A1 - Timpson, Nicholas J. A1 - Ong, Ken K. A1 - Bisgaard, Hans A1 - Bonnelykke, Klaus A1 - Jaddoe, Vincent W. V. A1 - Tiemeier, Henning A1 - Jarvelin, Marjo-Riitta A1 - Evans, David M. A1 - Perry, John R. B. A1 - Grant, Struan F. A. A1 - Boomsma, Dorret I. A1 - Freathy, Rachel M. A1 - McCarthy, Mark I. A1 - Felix, Janine F. T1 - The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia BT - design, results and future prospects JF - European journal of epidemiology N2 - The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites. KW - Genetics KW - Consortium KW - Childhood traits and disorders KW - Longitudinal Y1 - 2019 U6 - https://doi.org/10.1007/s10654-019-00502-9 SN - 0393-2990 SN - 1573-7284 VL - 34 IS - 3 SP - 279 EP - 300 PB - Springer CY - Dordrecht ER - TY - GEN A1 - Peter, Martin G. A1 - Boldt, Peter C. A1 - Niederstein, Yvonne A1 - Peter-Katalinić, Jasna T1 - Synthesen von Galactose-Cluster-haltigen Steroid-Derivaten N2 - The synthesis of galactose clusters that are linked to a steroid moiety by a peptide-like spacer unit is described. The galactose cluster is obtained by Koenigs-Knorr glycosylation of TRIS-Gly-Fmoc (2b) under Helferich conditions. Peptide and ester bonds are formed after activation of carboxylic acids as diphenylthiophene dioxide (TDO) esters. 6a is synthesized in a convergent way by coupling of (Ac4Gal)3-TRIS-Gly (3e) with cholesteryl TDO succinate (5b). Coupling of (Ac4Gal)3-TRIS-Gly hydrogen succinate (3f) with Gly-O-Chol (5d) by means of EEDQ yields 6d. Reaction of (Ac4Gal)3-TRIS-Gly-SUCC-O-TDO (3g) with 25-hydroxycholesterol leads in a linear sequence to the oxysterol derivative 6f. Selective cleavage of the acetyl groups from galactose units yields the known compound 6b and the new derivatives 6e and 6g. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 042 KW - Glycoconjugates KW - Galactosides KW - Steroid esters KW - Amphiphiles KW - Glycopeptides Y1 - 1990 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16783 ER - TY - JOUR A1 - Teriaca, Luca A1 - Andretta, Vincenzo A1 - Auchere, Frederic A1 - Brown, Charles M. A1 - Buchlin, Eric A1 - Cauzzi, Gianna A1 - Culhane, J. Len A1 - Curdt, Werner A1 - Davila, Joseph M. A1 - Del Zanna, Giulio A1 - Doschek, George A. A1 - Fineschi, Silvano A1 - Fludra, Andrzej A1 - Gallagher, Peter T. A1 - Green, Lucie A1 - Harra, Louise K. A1 - Imada, Shinsuke A1 - Innes, Davina A1 - Kliem, Bernhard A1 - Korendyke, Clarence A1 - Mariska, John T. A1 - Martinez-Pillet, Valentin A1 - Parenti, Susanna A1 - Patsourakos, Spiros A1 - Peter, Hardi A1 - Poletto, Luca A1 - Rutten, Robert J. A1 - Schuehle, Udo A1 - Siemer, Martin A1 - Shimizu, Toshifumi A1 - Socas-Navarro, Hector A1 - Solanki, Sami K. A1 - Spadaro, Daniele A1 - Trujillo-Bueno, Javier A1 - Tsuneta, Saku A1 - Dominguez, Santiago Vargas A1 - Vial, Jean-Claude A1 - Walsh, Robert A1 - Warren, Harry P. A1 - Wiegelmann, Thomas A1 - Winter, Berend A1 - Young, Peter T1 - LEMUR large european module for solar ultraviolet research JF - Experimental astronomy : an international journal on astronomical instrumentation and data analysis N2 - The solar outer atmosphere is an extremely dynamic environment characterized by the continuous interplay between the plasma and the magnetic field that generates and permeates it. Such interactions play a fundamental role in hugely diverse astrophysical systems, but occur at scales that cannot be studied outside the solar system. Understanding this complex system requires concerted, simultaneous solar observations from the visible to the vacuum ultraviolet (VUV) and soft X-rays, at high spatial resolution (between 0.1'' and 0.3''), at high temporal resolution (on the order of 10 s, i.e., the time scale of chromospheric dynamics), with a wide temperature coverage (0.01 MK to 20 MK, from the chromosphere to the flaring corona), and the capability of measuring magnetic fields through spectropolarimetry at visible and near-infrared wavelengths. Simultaneous spectroscopic measurements sampling the entire temperature range are particularly important. These requirements are fulfilled by the Japanese Solar-C mission (Plan B), composed of a spacecraft in a geosynchronous orbit with a payload providing a significant improvement of imaging and spectropolarimetric capabilities in the UV, visible, and near-infrared with respect to what is available today and foreseen in the near future. The Large European Module for solar Ultraviolet Research (LEMUR), described in this paper, is a large VUV telescope feeding a scientific payload of high-resolution imaging spectrographs and cameras. LEMUR consists of two major components: a VUV solar telescope with a 30 cm diameter mirror and a focal length of 3.6 m, and a focal-plane package composed of VUV spectrometers covering six carefully chosen wavelength ranges between 170 and 1270 . The LEMUR slit covers 280'' on the Sun with 0.14'' per pixel sampling. In addition, LEMUR is capable of measuring mass flows velocities (line shifts) down to 2 km s (-aEuro parts per thousand 1) or better. LEMUR has been proposed to ESA as the European contribution to the Solar C mission. KW - Sun: atmosphere KW - Space vehicles: instruments KW - Techniques: spectroscopy KW - ESA cosmic vision Y1 - 2012 U6 - https://doi.org/10.1007/s10686-011-9274-x SN - 0922-6435 VL - 34 IS - 2 SP - 273 EP - 309 PB - Springer CY - Dordrecht ER - TY - GEN A1 - Gorski, Mathias A1 - Jung, Bettina A1 - Li, Yong A1 - Matias-Garcia, Pamela R. A1 - Wuttke, Matthias A1 - Coassin, Stefan A1 - Thio, Chris H. L. A1 - Kleber, Marcus E. A1 - Winkler, Thomas W. A1 - Wanner, Veronika A1 - Chai, Jin-Fang A1 - Chu, Audrey Y. A1 - Cocca, Massimiliano A1 - Feitosa, Mary F. A1 - Ghasemi, Sahar A1 - Hoppmann, Anselm A1 - Horn, Katrin A1 - Li, Man A1 - Nutile, Teresa A1 - Scholz, Markus A1 - Sieber, Karsten B. A1 - Teumer, Alexander A1 - Tin, Adrienne A1 - Wang, Judy A1 - Tayo, Bamidele O. A1 - Ahluwalia, Tarunveer S. A1 - Almgren, Peter A1 - Bakker, Stephan J. L. A1 - Banas, Bernhard A1 - Bansal, Nisha A1 - Biggs, Mary L. A1 - Boerwinkle, Eric A1 - Böttinger, Erwin A1 - Brenner, Hermann A1 - Carroll, Robert J. A1 - Chalmers, John A1 - Chee, Miao-Li A1 - Chee, Miao-Ling A1 - Cheng, Ching-Yu A1 - Coresh, Josef A1 - de Borst, Martin H. A1 - Degenhardt, Frauke A1 - Eckardt, Kai-Uwe A1 - Endlich, Karlhans A1 - Franke, Andre A1 - Freitag-Wolf, Sandra A1 - Gampawar, Piyush A1 - Gansevoort, Ron T. A1 - Ghanbari, Mohsen A1 - Gieger, Christian A1 - Hamet, Pavel A1 - Ho, Kevin A1 - Hofer, Edith A1 - Holleczek, Bernd A1 - Foo, Valencia Hui Xian A1 - Hutri-Kahonen, Nina A1 - Hwang, Shih-Jen A1 - Ikram, M. Arfan A1 - Josyula, Navya Shilpa A1 - Kahonen, Mika A1 - Khor, Chiea-Chuen A1 - Koenig, Wolfgang A1 - Kramer, Holly A1 - Kraemer, Bernhard K. A1 - Kuehnel, Brigitte A1 - Lange, Leslie A. A1 - Lehtimaki, Terho A1 - Lieb, Wolfgang A1 - Loos, Ruth J. F. A1 - Lukas, Mary Ann A1 - Lyytikainen, Leo-Pekka A1 - Meisinger, Christa A1 - Meitinger, Thomas A1 - Melander, Olle A1 - Milaneschi, Yuri A1 - Mishra, Pashupati P. A1 - Mononen, Nina A1 - Mychaleckyj, Josyf C. A1 - Nadkarni, Girish N. A1 - Nauck, Matthias A1 - Nikus, Kjell A1 - Ning, Boting A1 - Nolte, Ilja M. A1 - O'Donoghue, Michelle L. A1 - Orho-Melander, Marju A1 - Pendergrass, Sarah A. A1 - Penninx, Brenda W. J. H. A1 - Preuss, Michael H. A1 - Psaty, Bruce M. A1 - Raffield, Laura M. A1 - Raitakari, Olli T. A1 - Rettig, Rainer A1 - Rheinberger, Myriam A1 - Rice, Kenneth M. A1 - Rosenkranz, Alexander R. A1 - Rossing, Peter A1 - Rotter, Jerome A1 - Sabanayagam, Charumathi A1 - Schmidt, Helena A1 - Schmidt, Reinhold A1 - Schoettker, Ben A1 - Schulz, Christina-Alexandra A1 - Sedaghat, Sanaz A1 - Shaffer, Christian M. A1 - Strauch, Konstantin A1 - Szymczak, Silke A1 - Taylor, Kent D. A1 - Tremblay, Johanne A1 - Chaker, Layal A1 - van der Harst, Pim A1 - van der Most, Peter J. A1 - Verweij, Niek A1 - Voelker, Uwe A1 - Waldenberger, Melanie A1 - Wallentin, Lars A1 - Waterworth, Dawn M. A1 - White, Harvey D. A1 - Wilson, James G. A1 - Wong, Tien-Yin A1 - Woodward, Mark A1 - Yang, Qiong A1 - Yasuda, Masayuki A1 - Yerges-Armstrong, Laura M. A1 - Zhang, Yan A1 - Snieder, Harold A1 - Wanner, Christoph A1 - Boger, Carsten A. A1 - Kottgen, Anna A1 - Kronenberg, Florian A1 - Pattaro, Cristian A1 - Heid, Iris M. T1 - Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline T2 - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät N2 - Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function. T3 - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät - 19 KW - acute kidney injury KW - end-stage kidney disease KW - genome-wide association KW - study KW - rapid eGFRcrea decline Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-565379 IS - 19 ER - TY - JOUR A1 - Gorski, Mathias A1 - Jung, Bettina A1 - Li, Yong A1 - Matias-Garcia, Pamela R. A1 - Wuttke, Matthias A1 - Coassin, Stefan A1 - Thio, Chris H. L. A1 - Kleber, Marcus E. A1 - Winkler, Thomas W. A1 - Wanner, Veronika A1 - Chai, Jin-Fang A1 - Chu, Audrey Y. A1 - Cocca, Massimiliano A1 - Feitosa, Mary F. A1 - Ghasemi, Sahar A1 - Hoppmann, Anselm A1 - Horn, Katrin A1 - Li, Man A1 - Nutile, Teresa A1 - Scholz, Markus A1 - Sieber, Karsten B. A1 - Teumer, Alexander A1 - Tin, Adrienne A1 - Wang, Judy A1 - Tayo, Bamidele O. A1 - Ahluwalia, Tarunveer S. A1 - Almgren, Peter A1 - Bakker, Stephan J. L. A1 - Banas, Bernhard A1 - Bansal, Nisha A1 - Biggs, Mary L. A1 - Boerwinkle, Eric A1 - Böttinger, Erwin A1 - Brenner, Hermann A1 - Carroll, Robert J. A1 - Chalmers, John A1 - Chee, Miao-Li A1 - Chee, Miao-Ling A1 - Cheng, Ching-Yu A1 - Coresh, Josef A1 - de Borst, Martin H. A1 - Degenhardt, Frauke A1 - Eckardt, Kai-Uwe A1 - Endlich, Karlhans A1 - Franke, Andre A1 - Freitag-Wolf, Sandra A1 - Gampawar, Piyush A1 - Gansevoort, Ron T. A1 - Ghanbari, Mohsen A1 - Gieger, Christian A1 - Hamet, Pavel A1 - Ho, Kevin A1 - Hofer, Edith A1 - Holleczek, Bernd A1 - Foo, Valencia Hui Xian A1 - Hutri-Kahonen, Nina A1 - Hwang, Shih-Jen A1 - Ikram, M. Arfan A1 - Josyula, Navya Shilpa A1 - Kahonen, Mika A1 - Khor, Chiea-Chuen A1 - Koenig, Wolfgang A1 - Kramer, Holly A1 - Kraemer, Bernhard K. A1 - Kuehnel, Brigitte A1 - Lange, Leslie A. A1 - Lehtimaki, Terho A1 - Lieb, Wolfgang A1 - Loos, Ruth J. F. A1 - Lukas, Mary Ann A1 - Lyytikainen, Leo-Pekka A1 - Meisinger, Christa A1 - Meitinger, Thomas A1 - Melander, Olle A1 - Milaneschi, Yuri A1 - Mishra, Pashupati P. A1 - Mononen, Nina A1 - Mychaleckyj, Josyf C. A1 - Nadkarni, Girish N. A1 - Nauck, Matthias A1 - Nikus, Kjell A1 - Ning, Boting A1 - Nolte, Ilja M. A1 - O'Donoghue, Michelle L. A1 - Orho-Melander, Marju A1 - Pendergrass, Sarah A. A1 - Penninx, Brenda W. J. H. A1 - Preuss, Michael H. A1 - Psaty, Bruce M. A1 - Raffield, Laura M. A1 - Raitakari, Olli T. A1 - Rettig, Rainer A1 - Rheinberger, Myriam A1 - Rice, Kenneth M. A1 - Rosenkranz, Alexander R. A1 - Rossing, Peter A1 - Rotter, Jerome A1 - Sabanayagam, Charumathi A1 - Schmidt, Helena A1 - Schmidt, Reinhold A1 - Schoettker, Ben A1 - Schulz, Christina-Alexandra A1 - Sedaghat, Sanaz A1 - Shaffer, Christian M. A1 - Strauch, Konstantin A1 - Szymczak, Silke A1 - Taylor, Kent D. A1 - Tremblay, Johanne A1 - Chaker, Layal A1 - van der Harst, Pim A1 - van der Most, Peter J. A1 - Verweij, Niek A1 - Voelker, Uwe A1 - Waldenberger, Melanie A1 - Wallentin, Lars A1 - Waterworth, Dawn M. A1 - White, Harvey D. A1 - Wilson, James G. A1 - Wong, Tien-Yin A1 - Woodward, Mark A1 - Yang, Qiong A1 - Yasuda, Masayuki A1 - Yerges-Armstrong, Laura M. A1 - Zhang, Yan A1 - Snieder, Harold A1 - Wanner, Christoph A1 - Boger, Carsten A. A1 - Kottgen, Anna A1 - Kronenberg, Florian A1 - Pattaro, Cristian A1 - Heid, Iris M. T1 - Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline JF - Kidney international : official journal of the International Society of Nephrology N2 - Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function. KW - acute kidney injury KW - end-stage kidney disease KW - genome-wide association KW - study KW - rapid eGFRcrea decline Y1 - 2020 U6 - https://doi.org/10.1016/j.kint.2020.09.030 SN - 0085-2538 SN - 1523-1755 VL - 99 IS - 4 SP - 926 EP - 939 PB - Elsevier CY - New York ER - TY - JOUR A1 - Dengler, Jürgen A1 - Wagner, Viktoria A1 - Dembicz, Iwona A1 - Garcia-Mijangos, Itziar A1 - Naqinezhad, Alireza A1 - Boch, Steffen A1 - Chiarucci, Alessandro A1 - Conradi, Timo A1 - Filibeck, Goffredo A1 - Guarino, Riccardo A1 - Janisova, Monika A1 - Steinbauer, Manuel J. A1 - Acic, Svetlana A1 - Acosta, Alicia T. R. A1 - Akasaka, Munemitsu A1 - Allers, Marc-Andre A1 - Apostolova, Iva A1 - Axmanova, Irena A1 - Bakan, Branko A1 - Baranova, Alina A1 - Bardy-Durchhalter, Manfred A1 - Bartha, Sandor A1 - Baumann, Esther A1 - Becker, Thomas A1 - Becker, Ute A1 - Belonovskaya, Elena A1 - Bengtsson, Karin A1 - Benito Alonso, Jose Luis A1 - Berastegi, Asun A1 - Bergamini, Ariel A1 - Bonini, Ilaria A1 - Bruun, Hans Henrik A1 - Budzhak, Vasyl A1 - Bueno, Alvaro A1 - Antonio Campos, Juan A1 - Cancellieri, Laura A1 - Carboni, Marta A1 - Chocarro, Cristina A1 - Conti, Luisa A1 - Czarniecka-Wiera, Marta A1 - De Frenne, Pieter A1 - Deak, Balazs A1 - Didukh, Yakiv P. A1 - Diekmann, Martin A1 - Dolnik, Christian A1 - Dupre, Cecilia A1 - Ecker, Klaus A1 - Ermakov, Nikolai A1 - Erschbamer, Brigitta A1 - Escudero, Adrian A1 - Etayo, Javier A1 - Fajmonova, Zuzana A1 - Felde, Vivian A. A1 - Fernandez Calzado, Maria Rosa A1 - Finckh, Manfred A1 - Fotiadis, Georgios A1 - Fracchiolla, Mariano A1 - Ganeva, Anna A1 - Garcia-Magro, Daniel A1 - Gavilan, Rosario G. A1 - Germany, Markus A1 - Giladi, Itamar A1 - Gillet, Francois A1 - Giusso del Galdo, Gian Pietro A1 - Gonzalez, Jose M. A1 - Grytnes, John-Arvid A1 - Hajek, Michal A1 - Hajkova, Petra A1 - Helm, Aveliina A1 - Herrera, Mercedes A1 - Hettenbergerova, Eva A1 - Hobohm, Carsten A1 - Huellbusch, Elisabeth M. A1 - Ingerpuu, Nele A1 - Jandt, Ute A1 - Jeltsch, Florian A1 - Jensen, Kai A1 - Jentsch, Anke A1 - Jeschke, Michael A1 - Jimenez-Alfaro, Borja A1 - Kacki, Zygmunt A1 - Kakinuma, Kaoru A1 - Kapfer, Jutta A1 - Kavgaci, Ali A1 - Kelemen, Andras A1 - Kiehl, Kathrin A1 - Koyama, Asuka A1 - Koyanagi, Tomoyo F. A1 - Kozub, Lukasz A1 - Kuzemko, Anna A1 - Kyrkjeeide, Magni Olsen A1 - Landi, Sara A1 - Langer, Nancy A1 - Lastrucci, Lorenzo A1 - Lazzaro, Lorenzo A1 - Lelli, Chiara A1 - Leps, Jan A1 - Loebel, Swantje A1 - Luzuriaga, Arantzazu L. A1 - Maccherini, Simona A1 - Magnes, Martin A1 - Malicki, Marek A1 - Marceno, Corrado A1 - Mardari, Constantin A1 - Mauchamp, Leslie A1 - May, Felix A1 - Michelsen, Ottar A1 - Mesa, Joaquin Molero A1 - Molnar, Zsolt A1 - Moysiyenko, Ivan Y. A1 - Nakaga, Yuko K. A1 - Natcheva, Rayna A1 - Noroozi, Jalil A1 - Pakeman, Robin J. A1 - Palpurina, Salza A1 - Partel, Meelis A1 - Paetsch, Ricarda A1 - Pauli, Harald A1 - Pedashenko, Hristo A1 - Peet, Robert K. A1 - Pielech, Remigiusz A1 - Pipenbaher, Natasa A1 - Pirini, Chrisoula A1 - Pleskova, Zuzana A1 - Polyakova, Mariya A. A1 - Prentice, Honor C. A1 - Reinecke, Jennifer A1 - Reitalu, Triin A1 - Pilar Rodriguez-Rojo, Maria A1 - Rolecek, Jan A1 - Ronkin, Vladimir A1 - Rosati, Leonardo A1 - Rosen, Ejvind A1 - Ruprecht, Eszter A1 - Rusina, Solvita A1 - Sabovljevic, Marko A1 - Maria Sanchez, Ana A1 - Savchenko, Galina A1 - Schuhmacher, Oliver A1 - Skornik, Sonja A1 - Sperandii, Marta Gaia A1 - Staniaszek-Kik, Monika A1 - Stevanovic-Dajic, Zora A1 - Stock, Marin A1 - Suchrow, Sigrid A1 - Sutcliffe, Laura M. E. A1 - Swacha, Grzegorz A1 - Sykes, Martin A1 - Szabo, Anna A1 - Talebi, Amir A1 - Tanase, Catalin A1 - Terzi, Massimo A1 - Tolgyesi, Csaba A1 - Torca, Marta A1 - Torok, Peter A1 - Tothmeresz, Bela A1 - Tsarevskaya, Nadezda A1 - Tsiripidis, Ioannis A1 - Tzonev, Rossen A1 - Ushimaru, Atushi A1 - Valko, Orsolya A1 - van der Maarel, Eddy A1 - Vanneste, Thomas A1 - Vashenyak, Iuliia A1 - Vassilev, Kiril A1 - Viciani, Daniele A1 - Villar, Luis A1 - Virtanen, Risto A1 - Kosic, Ivana Vitasovic A1 - Wang, Yun A1 - Weiser, Frank A1 - Went, Julia A1 - Wesche, Karsten A1 - White, Hannah A1 - Winkler, Manuela A1 - Zaniewski, Piotr T. A1 - Zhang, Hui A1 - Ziv, Yaron A1 - Znamenskiy, Sergey A1 - Biurrun, Idoia T1 - GrassPlot - a database of multi-scale plant diversity in Palaearctic grasslands JF - Phytocoenologia N2 - GrassPlot is a collaborative vegetation-plot database organised by the Eurasian Dry Grassland Group (EDGG) and listed in the Global Index of Vegetation-Plot Databases (GIVD ID EU-00-003). GrassPlot collects plot records (releves) from grasslands and other open habitats of the Palaearctic biogeographic realm. It focuses on precisely delimited plots of eight standard grain sizes (0.0001; 0.001;... 1,000 m(2)) and on nested-plot series with at least four different grain sizes. The usage of GrassPlot is regulated through Bylaws that intend to balance the interests of data contributors and data users. The current version (v. 1.00) contains data for approximately 170,000 plots of different sizes and 2,800 nested-plot series. The key components are richness data and metadata. However, most included datasets also encompass compositional data. About 14,000 plots have near-complete records of terricolous bryophytes and lichens in addition to vascular plants. At present, GrassPlot contains data from 36 countries throughout the Palaearctic, spread across elevational gradients and major grassland types. GrassPlot with its multi-scale and multi-taxon focus complements the larger international vegetationplot databases, such as the European Vegetation Archive (EVA) and the global database " sPlot". Its main aim is to facilitate studies on the scale-and taxon-dependency of biodiversity patterns and drivers along macroecological gradients. GrassPlot is a dynamic database and will expand through new data collection coordinated by the elected Governing Board. We invite researchers with suitable data to join GrassPlot. Researchers with project ideas addressable with GrassPlot data are welcome to submit proposals to the Governing Board. KW - biodiversity KW - European Vegetation Archive (EVA) KW - Eurasian Dry Grassland Group (EDGG) KW - grassland vegetation KW - GrassPlot KW - macroecology KW - multi-taxon KW - nested plot KW - scale-dependence KW - species-area relationship (SAR) KW - sPlot KW - vegetation-plot database Y1 - 2018 U6 - https://doi.org/10.1127/phyto/2018/0267 SN - 0340-269X VL - 48 IS - 3 SP - 331 EP - 347 PB - Cramer CY - Stuttgart ER - TY - BOOK A1 - Mientus, Lukas A1 - Klempin, Christiane A1 - Nowak, Anna A1 - Wyss, Corinne A1 - Aufschnaiter, Claudia von A1 - Faix, Ann-Christin A1 - te Poel, Kathrin A1 - Wahbe, Nadia A1 - Pieper, Martin A1 - Höller, Katharina A1 - Kallenbach, Lea A1 - Förster, Magdalena A1 - Redecker, Anke A1 - Dick, Mirjam A1 - Holle, Jörg A1 - Schneider, Edina A1 - Rehfeldt, Daniel A1 - Brauns, Sarah A1 - Abels, Simone A1 - Ferencik-Lehmkuhl, Daria A1 - Fränkel, Silvia A1 - Frohn, Julia A1 - Liebsch, Ann-Catherine A1 - Pech, Detlef A1 - Schreier, Pascal A1 - Jessen, Moiken A1 - Großmann, Uta A1 - Skintey, Lesya A1 - Voerkel, Paul A1 - Vaz Ferreira, Mergenfel A. A1 - Zimmermann, Jan-Simon A1 - Buddeberg, Magdalena A1 - Henke, Vanessa A1 - Hornberg, Sabine A1 - Völschow, Yvette A1 - Warrelmann, Julia-Nadine A1 - Malek, Jennifer A1 - Tinnefeld, Anja A1 - Schmidt, Peggy A1 - Bauer, Tobias A1 - Jänisch, Christopher A1 - Spitzer, Lisa A1 - Franken, Nadine A1 - Degeling, Maria A1 - Preisfeld, Angelika A1 - Meier, Jana A1 - Küth, Simon A1 - Scholl, Daniel A1 - Vogelsang, Christoph A1 - Watson, Christina A1 - Weißbach, Anna A1 - Kulgemeyer, Christoph A1 - Oetken, Mandy A1 - Gorski, Sebastian A1 - Kubsch, Marcus A1 - Sorge, Stefan A1 - Wulff, Peter A1 - Fellenz, Carolin D. A1 - Schnell, Susanne A1 - Larisch, Cathleen A1 - Kaiser, Franz A1 - Knott, Christina A1 - Reimer, Stefanie A1 - Stegmüller, Nathalie A1 - Boukrayâa Trabelsi, Kathrin A1 - Schißlbauer, Franziska A1 - Lemberger, Lukas A1 - Barth, Ulrike A1 - Wiehl, Angelika A1 - Rogge, Tim A1 - Böhnke, Anja A1 - Dietz, Dennis A1 - Großmann, Leroy A1 - Wienmeister, Annett A1 - Zoppke, Till A1 - Jiang, Lisa A1 - Grünbauer, Stephanie A1 - Ostersehlt, Dörte A1 - Peukert, Sophia A1 - Schäfer, Christoph A1 - Löbig, Anna A1 - Bröll, Leena A1 - Brandt, Birgit A1 - Breuer, Meike A1 - Dausend, Henriette A1 - Krelle, Michael A1 - Andersen, Gesine A1 - Falke, Sascha A1 - Kindermann-Güzel, Kristin A1 - Körner, Katrina A1 - Lottermoser, Lisa-Marie A1 - Pügner, Kati A1 - Sonnenburg, Nadine A1 - Akarsu, Selim A1 - Rechl, Friederike A1 - Gadinger, Laureen A1 - Heinze, Lena A1 - Wittmann, Eveline A1 - Franke, Manuela A1 - Lachmund, Anne-Marie A1 - Böttger, Julia A1 - Hannover, Bettina A1 - Behrendt, Renata A1 - Conty, Valentina A1 - Grundmann, Stephanie A1 - Ghassemi, Novid A1 - Opitz, Ben A1 - Brämer, Martin A1 - Gasparjan, David A1 - Sambanis, Michaela A1 - Köster, Hilde A1 - Lücke, Martin A1 - Nordmeier, Volkhard A1 - Schaal, Sonja A1 - Haberbosch, Maximilian A1 - Meissner, Maren A1 - Schaal, Steffen A1 - Brüchner, Melanie A1 - Riehle, Tamara A1 - Leopold, Bengta Marie A1 - Gerlach, Susanne A1 - Rau-Patschke, Sarah A1 - Skorsetz, Nina A1 - Weber, Nadine A1 - Damköhler, Jens A1 - Elsholz, Markus A1 - Trefzger, Thomas A1 - Lewek, Tobias A1 - Borowski, Andreas ED - Mientus, Lukas ED - Klempin, Christiane ED - Nowak, Anna T1 - Reflexion in der Lehrkräftebildung BT - Empirisch – Phasenübergreifend – Interdisziplinär T3 - Potsdamer Beiträge für Lehrkräftebildung und Bildungsforschung N2 - Reflexion ist eine Schlüsselkategorie für die professionelle Entwicklung von Lehrkräften, welche als Ausbildungsziel in den Bildungsstandards für die Lehrkräftebildung verankert ist. Eine Verstetigung universitär geprägter Forschung und Modellierung in der praxisnahen Anwendung im schulischen Kontext bietet Potentiale nachhaltiger Professionalisierung. Die Stärkung reflexionsbezogener Kompetenzen durch Empirie und Anwendung scheint eine phasenübergreifende Herausforderung der Lehrkräftebildung zu sein, die es zu bewältigen gilt. Ziele des Tagungsbandes Reflexion in der Lehrkräftebildung sind eine theoretische Schärfung des Konzeptes „Reflexive Professionalisierung“ und der Austausch über Fragen der Einbettung wirksamer reflexionsbezogener Lerngelegenheiten in die Lehrkräftebildung. Forschende und Lehrende der‚ drei Phasen (Studium, Referendariat sowie Fort- und Weiterbildung) der Lehrkräftebildung stellen Lehrkonzepte und Forschungsprojekte zum Thema Reflexion in der Lehrkräftebildung vor und diskutieren diese. Gemeinsam mit Teilnehmenden aller Phasen und von verschiedenen Standorten der Lehrkräftebildung werden zukünftige Herausforderungen identifiziert und Lösungsansätze herausgearbeitet. T3 - Potsdamer Beiträge zur Lehrkräftebildung und Bildungsforschung - 4 KW - Reflexion KW - Lehrkräftebildung KW - Reflexionskompetenz KW - Reflexivität KW - Feedback KW - Reflection KW - Teacher Education KW - Reflection Skills KW - Reflexivity KW - Feedback Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-591717 SN - 978-3-86956-566-8 SN - 2626-3556 SN - 2626-4722 IS - 4 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - THES A1 - Bahrke, Sven A1 - Einarsson, Jon M. A1 - Gislason, Johannes A1 - Haebel, Sophie A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Characterization of chitooligosaccharides by mass spectrometry Y1 - 2003 SN - 82-47-15901-5 ER - TY - JOUR A1 - Rusu, Viorel Marin A1 - Ng, C. H. A1 - Wilke, Max A1 - Tiersch, Brigitte A1 - Fratzl, Peter A1 - Peter, Martin G. T1 - Size-controlled hydroxyapatite nanoparticles as self-organized organic-in organic composite materials N2 - This paper presents some results concerning the size-controlled hydroxyapatite nanoparticles obtained in aqueous media in a biopolymer matrix from soluble precursors salts. Taking the inspiration from nature, where composite materials made of a polymer matrix and inorganic fillers are often found, e.g. bone, shell of crustaceans, shell of eggs, etc., the feasibility on making composite materials containing chitosan and nanosized hydroxyapatite was investigated. A stepwise co-precipitation approach was used to obtain different types of composites by means of different ratio between components. The synthesis of hydroxyapatite was carried out in the chitosan matrix from calcium chloride and sodium dihydrogenphosphate in alkaline solutions at moderate pH of 10-11 for 24 h. Our research is focused on studying and understanding the structure of this class of composites, aiming at the development of novel materials, controlled at the nanolevel scale. The X-ray diffraction technique was employed in order to study the kinetic of hydroxyapatite formation in the chitosan matrix as well as to determine the HAp crystallite sizes in the composite samples. The hydroxyapatite synthesized using this route was found to be nano-sized (15-50nm). Moreover, applying an original approach to analyze the (002) XRD diffraction peak profile of hydroxyapatite by using a sum of two Gauss functions, the bimodal distribution of nanosized hydroxyapatite within the chitosan matrix was revealed. Two types of size distribution domains such as cluster-like (between 200 and 400 nm), which are the habitat of "small" hydroxyapatite nanocrystallites and scattered-like, which are the habitat of "large" hydroxyapatite nanocrystallites was probed by TEM and CSLM. The structural features of composites suggest that self-assembly processes might be involved. The composites contain nanosized hydroxyapatite with structural features close to those of biological apatites that make them attractive for bone tissue engineering applications. (c) 2005 Elsevier Ltd. All rights reserved Y1 - 2005 SN - 0142-9612 ER - TY - GEN A1 - Peter, Martin G. A1 - Andersen, Svend Olav A1 - Hartmann, Rudolf A1 - Miessner, Merle A1 - Roepstorff, Peter T1 - Catecholamine-protein conjugates : isolation of 4-phenylphenoxazin-2-ones from oxidative coupling of N-acetyldopamine with alipathic amino acids N2 - 4-Phenylphenoxazinones were isolated after biomimetic oxidation, using diphenoloxidases of insect cuticle, mushroom tyrosinase, or after autoxidation of N-acetyldopamine (Image ) in the presence of β-alanine, β-alanine methyl ester or N-acetyl-L-lysine. They are formed presumably by addition of 2-aminoalkyl-5-alkylphenols to the o-quinone of biphenyltetrol which, in turn, arises from oxidative coupling of. The structures of present the first examples for the assembly of reasonably stable intermediates in the rather complex process of chemical modifications of aliphatic amino acid residues by o-quinones. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 062 Y1 - 1992 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-17571 ER - TY - GEN A1 - Peter, Martin G. A1 - Stupp, Hans-Peter A1 - Lentes, Klaus-Ulrich T1 - Umkehr der Enantioselektivität bei der enzymatischen Hydrolyse von Juvenilhormon als Ergebnis einer Proteinfraktionierung N2 - Aus dem Inhalt: Die Juvenilhormone 1a-c werden im Blut von Insekten enzymatisch zu den biologisch inaktiven Sluren hydrolysiert. Bei der Hydrolyse von racemischem 1c im Blut der Wanderheuschrecke Locusta migratoria wird ein Umsatz von 40-60% erreicht. Das unumgesetzte Edukt enthällt einen Überschuß an natürlich konfiguriertem (10R)-1c (e.e. 47.2%). Wir konnten zeigen, daß das in der Hämolymphe vorhandene Hormon-Bindungsprotein bevorzugt mit (10R)- 1c assoziiert. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 052 Y1 - 1983 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-17001 ER - TY - JOUR A1 - Andersen, S. O. A1 - Peter, Martin G. A1 - Roepstorff, Peter T1 - Cuticular sclerotization in insects Y1 - 1996 ER - TY - JOUR A1 - Haebel, Sophie A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Mass spectrometry of chitooligosaccharides Y1 - 1997 SN - 88-86889- 01-1 ER - TY - JOUR A1 - Cederkvist, F. Henning A1 - Zamfir, Alina D. A1 - Bahrke, Sven A1 - Eijsink, Vincent G. H. A1 - Sorlie, Morten A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Identification of a high-affinity-binding oligosaccharide by (+) nanoelectrospray quadrupole time-of-flight tandem mass spectrometry of a noncovalent enzyme-ligand complex Y1 - 2006 UR - http://www3.interscience.wiley.com/cgi-bin/jhome/26737/ U6 - https://doi.org/10.1002/anie.200503168 SN - 1433-7851 ER - TY - JOUR A1 - Selting, Margret A1 - Auer, Peter A1 - Barth-Weingarten, Dagmar A1 - Bergmann, Jörg A1 - Bergmann, Pia A1 - Birkner, Karin A1 - Couper-Kuhlen, Elizabeth A1 - Deppermann, Arnulf A1 - Gilles, Peter A1 - Günthner, Susanne A1 - Hartung, Martin A1 - Kern, Friederike A1 - Mertzlufft, Christine A1 - Meyer, Christian A1 - Morek, Miriam A1 - Oberzaucher, Frank A1 - Peters, Jörg A1 - Quasthoff, Uta A1 - Schütte, Wilfried A1 - Stukenbrock, Anja A1 - Uhmann, Susanne T1 - Gesprächsanalytisches Transkriptionssystem 2 (GAT 2) Y1 - 2009 UR - http://www.gespraechsforschung-ozs.de/heft2009/px-gat2.pdf (12.9.13) SN - 1617-1837 ER - TY - CHAP A1 - Hofuku, Yayoi A1 - Cho, Shinya A1 - Nishida, Tomohiro A1 - Kanemune, Susumu A1 - Linck, Barbara A1 - Kim, Seungyon A1 - Park, Seongbin A1 - Vaníček, Jiří A1 - Gujberová, Monika A1 - Tomcsányi, Peter A1 - Dagiene, Valentina A1 - Jevsikova, Tatjana A1 - Schulte, Carsten A1 - Sentance, Sue A1 - Thota, Neena A1 - Gülbahar, Yasemin A1 - İlkhan, Mustafa A1 - Kilis, Selcan A1 - Arslan, Okan A1 - Nakano, Yoshiaki A1 - Izutsu, Katsunobu A1 - Lessner, Daniel A1 - Reffay, Christophe A1 - Miled, Mahdi A1 - Ortiz, Pascal A1 - Février, Loïc A1 - Grgurina, Nataša A1 - Weise, Martin A1 - Bellettini, Carlo A1 - Lonati, Violetta A1 - Malchiodi, Dario A1 - Monga, Mattia A1 - Morpurgo, Anna A1 - Torelli, Mauro A1 - Planteu, Lukas A1 - Standl, Bernhard A1 - Grossmann, Wilfried A1 - Neuwirth, Erich A1 - Benacka, Jan A1 - Ragonis, Noa A1 - Hodges, Steve A1 - Berry, Carol A1 - Kusterer, Peter ED - Diethelm, Ira ED - Arndt, Jannik ED - Dünnebier, Malte ED - Syrbe, Jörn T1 - Informatics in schools : local proceedings of the 6th International Conference ISSEP 2013 ; selected papers ; Oldenburg, Germany, February 26–March 2, 2013 N2 - The International Conference on Informatics in Schools: Situation, Evolution and Perspectives – ISSEP – is a forum for researchers and practitioners in the area of Informatics education, both in primary and secondary schools. It provides an opportunity for educators to reflect upon the goals and objectives of this subject, its curricula and various teaching/learning paradigms and topics, possible connections to everyday life and various ways of establishing Informatics Education in schools. This conference also cares about teaching/learning materials, various forms of assessment, traditional and innovative educational research designs, Informatics’ contribution to the preparation of children for the 21st century, motivating competitions, projects and activities supporting informatics education in school. T3 - Commentarii informaticae didacticae (CID) - 6 KW - ISSEP KW - Informatics Education Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-63688 SN - 978-3-86956-222-3 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Bahrke, Sven A1 - Einarsson, Jon M. A1 - Gislason, Johannes A1 - Haebel, Sophie A1 - Letzel, Matthias C. A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Sequence analysis of chitooligosaccharides by matrix-assisted laser desorption ionization postsource decay mass spectrometry N2 - Oligosaccharides composed of 2-acetamido-2-deoxy-D-glucopyranose (GlcNAc) and/or 2-amino-2-deoxy-D- glucopyranose (GlcN) were prepd. by chem. degrdn. of chitin or chitosan and sepd. by gel permeation chromatog. Oligosaccharides obtained after enzymic hydrolysis of chitosan [FA 0.19] with a fungal chitinase were derivatized by reductive amination with 2-aminoacridone and sequenced by matrix-assisted laser desorption ionization time-of-flight postsource decay (PSD) mass spectrometry (MS). The sequence of a trimer, D1A2, was established as D-A-A. The compn. of a hexamer D3A3 was .apprx.65% D-A-D-D-A-A and 35% D-D-A-D-A-A. The PSD MS of a nonamer D5A4-amac revealed four isobaric species D-X-Y-D-X-Y-D-A-A, where A is GlcNAc, D is GlcN, and X and Y (X ¹ Y) are mutually either D or A. This structure motif was also obsd. in a dodecamer D7A5 which was composed of eight isobaric sequences of the general formula (D-X-Y)3- D-A-A. Y1 - 2002 ER - TY - JOUR A1 - Letzel, Matthias C. A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Mass spectrometry of chitin and chitosan oligosaccharides Y1 - 2001 ER - TY - JOUR A1 - Letzel, Matthias C. A1 - Synstad, Bjoenar A1 - Eijsink, Vincent G. H. A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Libraries of chito-oligosaccharides of mixed acetylation patterns and their interactions with chitinases Y1 - 1999 SN - 3-9806494-5-8 ER - TY - JOUR A1 - Juma, Wanyama P. A1 - Akala, Hoseah M. A1 - Eyase, Fredrick L. A1 - Muiva, Lois M. A1 - Heydenreich, Matthias A1 - Okalebo, Faith A. A1 - Gitu, Peter M. A1 - Peter, Martin G. A1 - Walsh, Douglas S. A1 - Imbuga, Mabel A1 - Yenesew, Abiy T1 - Terpurinflavone an antiplasmodial flavone from the stem of Tephrosia Purpurea JF - Phytochemistry letters N2 - The stem extract of Tephrosia purpurea showed antiplasmodial activity against the D6 (chloroquine-sensitive) and W2 (chloroquine-resistant) strains of Plasmodium falciparum with IC(50) values of 10.47 +/- 2.22 mu g/ml and 12.06 +/- 2.54 mu g/ml, respectively. A new prenylated flavone, named terpurinflavone, along with the known compounds lanceolatin A, (-)-semiglabrin and lanceolatin B have been isolated from this extract. The new compound, terpurinflavone, showed the highest antiplasmodial activity with IC(50) values of 3.12 +/- 0.28 mu M (D6) and 6.26 +/- 2.66 mu M (W2). The structures were determined on the basis of spectroscopic evidence. KW - Tephrosia purpurea KW - Leguminosae KW - Stem KW - Flavone KW - Terpurinflavone KW - Antiplasmodial Y1 - 2011 U6 - https://doi.org/10.1016/j.phytol.2011.02.010 SN - 1874-3900 VL - 4 IS - 2 SP - 176 EP - 178 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Andayi, Andrew W. A1 - Yenesew, Abiy A1 - Derese, Solomon A1 - Midiwo, Jacob O. A1 - Gitu, Peter M. A1 - Jondiko, Ogoche J. I. A1 - Akala, Hoseah M. A1 - Liyala, Pamela A1 - Wangui, Julia A1 - Waters, Norman C. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - Antiplasmodial flavonoids from Erythrina sacleuxii N2 - The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the acetone extract of the root bark afforded a new isoflavone, 7-hydroxy-4 -methoxy-3'- prenylisoflavone (trivial name 5-deoxy-3' - prenylbiochanin A) along with known isoflavonoids as the antiplasmodial principles. Flavonoids and isoflavonoids isolated from the stem bark of E. sucleuxii were also tested and showed antiplasmodial activities. The structures were determined on the basis of spectroscopic evidence Y1 - 2006 UR - http://www.thieme-connect.com/ejournals/toc/plantamedica U6 - https://doi.org/10.1055/s-2005-873200 SN - 0032-0943 ER - TY - JOUR A1 - Yildirim, Cengiz A1 - Schildgen, Taylor F. A1 - Echtler, Helmut Peter A1 - Melnick, Daniel A1 - Bookhagen, Bodo A1 - Ciner, T. Attila A1 - Niedermann, Samuel A1 - Merchel, Silke A1 - Martschini, Martin A1 - Steier, Peter A1 - Strecker, Manfred T1 - Tectonic implications of fluvial incision and pediment deformation at the northern margin of the Central Anatolian Plateau based on multiple cosmogenic nuclides JF - Tectonics N2 - We document Quaternary fluvial incision driven by fault-controlled surface deformation in the inverted intermontane Gökirmak Basin in the Central Pontide mountains along the northern margin of the Central Anatolian Plateau. In-situ-produced Be-10, Ne-21, and Cl-36 concentrations from gravel-covered fluvial terraces and pediment surfaces along the trunk stream of the basin (the Gökirmak River) yield model exposure ages ranging from 71ka to 34645ka and average fluvial incision rates over the past similar to 350ka of 0.280.01mm a(-1). Similarities between river incision rates and coastal uplift rates at the Black Sea coast suggest that regional uplift is responsible for the river incision. Model exposure ages of deformed pediment surfaces along tributaries of the trunk stream range from 605ka to 110 +/- 10ka, demonstrating that the thrust faults responsible for pediment deformation were active after those times and were likely active earlier as well as explaining the topographic relief of the region. Together, our data demonstrate cumulative incision that is linked to active internal shortening and uplift of similar to 0.3mm a(-1) in the Central Pontide orogenic wedge, which may ultimately contribute to the lateral growth of the northern Anatolian Plateau. KW - Tectonic Geomorphology KW - Fluvial Incision KW - Surface Exposure Age KW - Uplift Rate Y1 - 2013 U6 - https://doi.org/10.1002/tect.20066 SN - 0278-7407 SN - 1944-9194 VL - 32 IS - 5 SP - 1107 EP - 1120 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Gläser, Stefanie P. A1 - Bolte, Kathrin A1 - Martin, Karin A1 - Busse, Hans-Jürgen A1 - Grossart, Hans-Peter A1 - Kämpfer, Peter A1 - Gläser, Jens T1 - Novosphingobium fuchskuhlense sp nov., isolated from the north-east basin of Lake Grosse Fuchskuhle JF - International journal of systematic and evolutionary microbiology N2 - A yellow pigmented, Gram-negative, rod-shaped bacterium designated FNE08-7(T) was isolated from subsurface water of the north-east basin of the bog lake Grosse Fuchskuhle (Brandenburg, Germany). A first analysis of the nearly full-length 16S rRNA gene sequence analysis including environmental 16S rRNA gene sequences derived from freshwater ecosystems showed that strain FNE08-7(T) is the first cultured representative, to our knowledge, of the freshwater tribe Novo-A2. Further analysis indicates highest 16S rRNA gene sequence similarities to the type strains of Novosphingobium stygium (98.0%) and Novosphingobium taihuense (97.4%) and between 94.0% and 96.9% sequence similarity to other members of the genus Novosphingobium. Reconstruction of phylogenetic trees showed that strain FNE08-7(T) formed a distinct cluster with the type strains of N. stygium and N. taihuense supported by high bootstrap values. DNA DNA hybridization of strain FNE08-7(T) with N. stygium SMCC B0712(T) and N. taihuense DSM 17507(T) revealed low similarity values of 18.4% (reciprocal: 11.4%) and 23.1% (reciprocal: 54.2%), respectively. The predominant fatty acid of the isolate is C-18:1 omega 7c (56.4%) and two characteristic 2-hydroxy fatty acids, C-14:0 2-OH (16.5%) and C-15:0 2-OH (3.3%) occur. Ubiquinone Q-10 is the major respiratory quinone. The predominant polar lipids are phosphatidylethanolamine, phosphatidylmethylethanolamine, phosphatidylglycerol, sphingoglycolipid, phosphatidylcholine and minor amounts of diphosphatidylglycerol. Spermidine is the predominant polyamine. Characterization by genotypic, chemotaxonomic and phenotypic analysis indicate that strain FNE08-7(T) represents a novel species of the genus Novosphingobium within the Alphaproteobacteria. Therefore, we propose the species Novosphingobium fuchskuhlense sp. nov., with FNE08-7(T) (=DSM 25065(T)=CCM 7978(T)=CCUG 61508(T)) as the type strain. Y1 - 2013 U6 - https://doi.org/10.1099/ijs.0.043083-0 SN - 1466-5026 VL - 63 SP - 586 EP - 592 PB - Society for General Microbiology CY - Reading ER - TY - JOUR A1 - Schellenberg, Johannes A1 - Reichert, Jessica A1 - Hardt, Martin A1 - Klingelhöfer, Ines A1 - Morlock, Gertrud A1 - Schubert, Patrick A1 - Bižić, Mina A1 - Grossart, Hans-Peter A1 - Kämpfer, Peter A1 - Wilke, Thomas A1 - Glaeser, Stefanie P. T1 - The bacterial microbiome of the long-term aquarium cultured high-microbial abundance sponge Haliclona cnidata BT - sustained bioactivity despite community shifts under detrimental conditions JF - Frontiers in Marine Science N2 - Marine sponges host highly diverse but specific bacterial communities that provide essential functions for the sponge holobiont, including antimicrobial defense. Here, we characterized the bacterial microbiome of the marine sponge Haliclona cnidata that has been in culture in an artificial marine aquarium system. We tested the hypotheses (1) that the long-term aquarium cultured sponge H. cnidata is tightly associated with a typical sponge bacterial microbiota and (2) that the symbiotic Bacteria sustain bioactivity under harmful environmental conditions to facilitate holobiont survival by preventing pathogen invasion. Microscopic and phylogenetic analyses of the bacterial microbiota revealed that H. cnidata represents a high microbial abundance (HMA) sponge with a temporally stable bacterial community that significantly shifts with changing aquarium conditions. A 4-week incubation experiment was performed in small closed aquarium systems with antibiotic and/or light exclusion treatments to reduce the total bacterial and photosynthetically active sponge-associated microbiota to a treatment-specific resilient community. While the holobiont was severely affected by the experimental treatment (i.e., bleaching of the sponge, reduced bacterial abundance, shifted bacterial community composition), the biological defense and bacterial community interactions (i.e., quorum sensing activity) remained intact. 16S rRNA gene amplicon sequencing revealed a resilient community of 105 bacterial taxa, which remained in the treated sponges. These 105 taxa accounted for a relative abundance of 72-83% of the bacterial sponge microbiota of non-treated sponge fragments that have been cultured under the same conditions. We conclude that a sponge-specific resilient community stays biologically active under harmful environmental conditions, facilitating the resilience of the holobiont. In H. cnidata, bacteria are located in bacteriocytes, which may have contributed to the observed phenomenon. KW - HMA sponge KW - bacterial symbionts KW - holobiont KW - antimicrobial defense KW - quorum sensing KW - bacteriocytes Y1 - 2020 U6 - https://doi.org/10.3389/fmars.2020.00266 SN - 2296-7745 VL - 7 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Schulze-Makuch, Dirk A1 - Wagner, Dirk A1 - Kounaves, Samuel P. A1 - Mangelsdorf, Kai A1 - Devine, Kevin G. A1 - de Vera, Jean-Pierre A1 - Schmitt-Kopplin, Philippe A1 - Grossart, Hans-Peter A1 - Parro, Victor A1 - Kaupenjohann, Martin A1 - Galy, Albert A1 - Schneider, Beate A1 - Airo, Alessandro A1 - Froesler, Jan A1 - Davila, Alfonso F. A1 - Arens, Felix L. A1 - Caceres, Luis A1 - Cornejo, Francisco Solis A1 - Carrizo, Daniel A1 - Dartnell, Lewis A1 - DiRuggiero, Jocelyne A1 - Flury, Markus A1 - Ganzert, Lars A1 - Gessner, Mark O. A1 - Grathwohl, Peter A1 - Guan, Lisa A1 - Heinz, Jacob A1 - Hess, Matthias A1 - Keppler, Frank A1 - Maus, Deborah A1 - McKay, Christopher P. A1 - Meckenstock, Rainer U. A1 - Montgomery, Wren A1 - Oberlin, Elizabeth A. A1 - Probst, Alexander J. A1 - Saenz, Johan S. A1 - Sattler, Tobias A1 - Schirmack, Janosch A1 - Sephton, Mark A. A1 - Schloter, Michael A1 - Uhl, Jenny A1 - Valenzuela, Bernardita A1 - Vestergaard, Gisle A1 - Woermer, Lars A1 - Zamorano, Pedro T1 - Transitory microbial habitat in the hyperarid Atacama Desert JF - Proceedings of the National Academy of Sciences of the United States of America KW - habitat KW - aridity KW - microbial activity KW - biomarker KW - Mars Y1 - 2018 U6 - https://doi.org/10.1073/pnas.1714341115 SN - 0027-8424 VL - 115 IS - 11 SP - 2670 EP - 2675 PB - National Acad. of Sciences CY - Washington ER - TY - JOUR A1 - Giesers, Benjamin David A1 - Kamann, Sebastian A1 - Dreizler, Stefan A1 - Husser, Tim-Oliver A1 - Askar, Abbas A1 - Göttgens, Fabian A1 - Brinchmann, Jarle A1 - Latour, Marilyn A1 - Weilbacher, Peter Michael A1 - Wendt, Martin A1 - Roth, Martin M. T1 - A stellar census in globular clusters with MUSE: Binaries in NGC 3201 JF - Astronomy and astrophysics : an international weekly journal N2 - We utilise multi-epoch MUSE spectroscopy to study binary stars in the core of the Galactic globular cluster NGC 3201. Our sample consists of 3553 stars with 54 883 spectra in total comprising 3200 main-sequence stars up to 4 magnitudes below the turn-off. Each star in our sample has between 3 and 63 (with a median of 14) reliable radial velocity measurements within five years of observations. We introduce a statistical method to determine the probability of a star showing radial velocity variations based on the whole inhomogeneous radial velocity sample. Using HST photometry and an advanced dynamical MOCCA simulation of this specific cluster we overcome observational biases that previous spectroscopic studies had to deal with. This allows us to infer a binary frequency in the MUSE field of view and enables us to deduce the underlying true binary frequency of (6.75 +/- 0.72)% in NGC 3201. The comparison of the MUSE observations with the MOCCA simulation suggests a large portion of primordial binaries. We can also confirm a radial increase in the binary fraction towards the cluster centre due to mass segregation. We discovered that in the core of NGC 3201 at least (57.5 +/- 7.9)% of blue straggler stars are in a binary system. For the first time in a study of globular clusters, we were able to fit Keplerian orbits to a significant sample of 95 binaries. We present the binary system properties of eleven blue straggler stars and the connection to SX Phoenicis-type stars. We show evidence that two blue straggler formation scenarios, the mass transfer in binary (or triple) star systems and the coalescence due to binary-binary interactions, are present in our data. We also describe the binary and spectroscopic properties of four sub-subgiant (or red straggler) stars. Furthermore, we discovered two new black hole candidates with minimum masses (M sin i) of (7.68 +/- 0.50)M-circle dot, (4.4 +/- 2.8)M-circle dot, and refine the minimum mass estimate on the already published black hole to (4.53 +/- 0.21)M-circle dot, These black holes are consistent with an extensive black hole subsystem hosted by NGC 3201. KW - binaries: general KW - blue stragglers KW - stars: black holes KW - techniques: radial velocities KW - techniques: imaging spectroscopy KW - globular clusters: individual: NGC 3201 Y1 - 2019 U6 - https://doi.org/10.1051/0004-6361/201936203 SN - 0004-6361 SN - 1432-0746 VL - 632 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Göttgens, Fabian A1 - Weilbacher, Peter Michael A1 - Roth, Martin M. A1 - Dreizler, Stefan A1 - Giesers, Benjamin A1 - Husser, Tim-Oliver A1 - Kamann, Sebastian A1 - Brinchmann, Jarle A1 - Kollatschny, Wolfram A1 - Monreal-Ibero, Ana A1 - Schmidt, Kasper Borello A1 - Wendt, Martin A1 - Wisotzki, Lutz A1 - Bacon, Roland T1 - Discovery of an old nova remnant in the Galactic globular cluster M 22 JF - Astronomy and astrophysics : an international weekly journal N2 - A nova is a cataclysmic event on the surface of a white dwarf in a binary system that increases the overall brightness by several orders of magnitude. Although binary systems with a white dwarf are expected to be overabundant in globular clusters compared with in the Galaxy, only two novae from Galactic globular clusters have been observed. We present the discovery of an emission nebula in the Galactic globular cluster M 22 (NGC 6656) in observations made with the integral-field spectrograph MUSE. We extracted the spectrum of the nebula and used the radial velocity determined from the emission lines to confirm that the nebula is part of NGC 6656. Emission-line ratios were used to determine the electron temperature and density. It is estimated to have a mass of 1-17 x 10(-5) M-circle dot. This mass and the emission-line ratios indicate that the nebula is a nova remnant. Its position coincides with the reported location of a "guest star", an ancient Chinese term for transients, observed in May 48 BCE. With this discovery, this nova may be one of the oldest confirmed extra-solar events recorded in human history. KW - globular clusters: individual: NGC 6656 KW - novae, cataclysmic variables KW - techniques: imaging spectroscopy Y1 - 2019 U6 - https://doi.org/10.1051/0004-6361/201935221 SN - 1432-0746 VL - 626 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Kamann, Sebastian A1 - Husser, T. -O. A1 - Dreizler, S. A1 - Emsellem, E. A1 - Weilbacher, Peter Michael A1 - Martens, S. A1 - Bacon, R. A1 - den Brok, M. A1 - Giesers, B. A1 - Krajnovic, Davor A1 - Roth, Martin M. A1 - Wendt, Martin A1 - Wisotzki, Lutz T1 - A stellar census in globular clusters with MUSE BT - the contribution of rotation to cluster dynamics studied with 200 000 stars JF - Monthly notices of the Royal Astronomical Society N2 - This is the first of a series of papers presenting the results from our survey of 25 Galactic globular clusters with the MUSE integral-field spectrograph. In combination with our dedicated algorithm for source deblending, MUSE provides unique multiplex capabilities in crowded stellar fields and allows us to acquire samples of up to 20 000 stars within the half-light radius of each cluster. The present paper focuses on the analysis of the internal dynamics of 22 out of the 25 clusters, using about 500 000 spectra of 200 000 individual stars. Thanks to the large stellar samples per cluster, we are able to perform a detailed analysis of the central rotation and dispersion fields using both radial profiles and two-dimensional maps. The velocity dispersion profiles we derive show a good general agreement with existing radial velocity studies but typically reach closer to the cluster centres. By comparison with proper motion data, we derive or update the dynamical distance estimates to 14 clusters. Compared to previous dynamical distance estimates for 47 Tuc, our value is in much better agreement with other methods. We further find significant (>3 sigma) rotation in the majority (13/22) of our clusters. Our analysis seems to confirm earlier findings of a link between rotation and the ellipticities of globular clusters. In addition, we find a correlation between the strengths of internal rotation and the relaxation times of the clusters, suggesting that the central rotation fields are relics of the cluster formation that are gradually dissipated via two-body relaxation. KW - techniques: imaging spectroscopy KW - stars: kinematics and dynamics KW - globular clusters: general Y1 - 2017 U6 - https://doi.org/10.1093/mnras/stx2719 SN - 0035-8711 SN - 1365-2966 VL - 473 IS - 4 SP - 5591 EP - 5616 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Göttgens, Fabian A1 - Husser, Tim-Oliver A1 - Kamann, Sebastian A1 - Dreizler, Stefan A1 - Giesers, Benjamin A1 - Kollatschny, Wolfram A1 - Weilbacher, Peter Michael A1 - Roth, Martin M. A1 - Wendt, Martin T1 - A stellar census in globular clusters with MUSE: A spectral catalogue of emission-line sources JF - Astronomy and astrophysics : an international weekly journal N2 - Aims. Globular clusters produce many exotic stars due to a much higher frequency of dynamical interactions in their dense stellar environments. Some of these objects were observed together with several hundred thousand other stars in our MUSE survey of 26 Galactic globular clusters. Assuming that at least a few exotic stars have exotic spectra (i.e. spectra that contain emission lines), we can use this large spectroscopic data set of over a million stellar spectra as a blind survey to detect stellar exotica in globular clusters. Methods. To detect emission lines in each spectrum, we modelled the expected shape of an emission line as a Gaussian curve. This template was used for matched filtering on the di fferences between each observed 1D spectrum and its fitted spectral model. The spectra with the most significant detections of H alpha emission are checked visually and cross-matched with published catalogues. Results. We find 156 stars with H alpha emission, including several known cataclysmic variables (CV) and two new CVs, pulsating variable stars, eclipsing binary stars, the optical counterpart of a known black hole, several probable sub-subgiants and red stragglers, and 21 background emission-line galaxies. We find possible optical counterparts to 39 X-ray sources, as we detected H alpha emission in several spectra of stars that are close to known positions of Chandra X-ray sources. This spectral catalogue can be used to supplement existing or future X-ray or radio observations with spectra of potential optical counterparts to classify the sources. KW - globular clusters: general KW - stars: emission-line, Be KW - novae KW - cataclysmic variables KW - catalogs KW - techniques: imaging spectroscopy Y1 - 2019 U6 - https://doi.org/10.1051/0004-6361/201936485 SN - 0004-6361 SN - 1432-0746 VL - 631 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Aarts, Alexander A. A1 - Anderson, Joanna E. A1 - Anderson, Christopher J. A1 - Attridge, Peter R. A1 - Attwood, Angela A1 - Axt, Jordan A1 - Babel, Molly A1 - Bahnik, Stepan A1 - Baranski, Erica A1 - Barnett-Cowan, Michael A1 - Bartmess, Elizabeth A1 - Beer, Jennifer A1 - Bell, Raoul A1 - Bentley, Heather A1 - Beyan, Leah A1 - Binion, Grace A1 - Borsboom, Denny A1 - Bosch, Annick A1 - Bosco, Frank A. A1 - Bowman, Sara D. A1 - Brandt, Mark J. A1 - Braswell, Erin A1 - Brohmer, Hilmar A1 - Brown, Benjamin T. A1 - Brown, Kristina A1 - Bruening, Jovita A1 - Calhoun-Sauls, Ann A1 - Callahan, Shannon P. A1 - Chagnon, Elizabeth A1 - Chandler, Jesse A1 - Chartier, Christopher R. A1 - Cheung, Felix A1 - Christopherson, Cody D. A1 - Cillessen, Linda A1 - Clay, Russ A1 - Cleary, Hayley A1 - Cloud, Mark D. A1 - Cohn, Michael A1 - Cohoon, Johanna A1 - Columbus, Simon A1 - Cordes, Andreas A1 - Costantini, Giulio A1 - Alvarez, Leslie D. Cramblet A1 - Cremata, Ed A1 - Crusius, Jan A1 - DeCoster, Jamie A1 - DeGaetano, Michelle A. A1 - Della Penna, Nicolas A1 - den Bezemer, Bobby A1 - Deserno, Marie K. A1 - Devitt, Olivia A1 - Dewitte, Laura A1 - Dobolyi, David G. A1 - Dodson, Geneva T. A1 - Donnellan, M. Brent A1 - Donohue, Ryan A1 - Dore, Rebecca A. A1 - Dorrough, Angela A1 - Dreber, Anna A1 - Dugas, Michelle A1 - Dunn, Elizabeth W. A1 - Easey, Kayleigh A1 - Eboigbe, Sylvia A1 - Eggleston, Casey A1 - Embley, Jo A1 - Epskamp, Sacha A1 - Errington, Timothy M. A1 - Estel, Vivien A1 - Farach, Frank J. A1 - Feather, Jenelle A1 - Fedor, Anna A1 - Fernandez-Castilla, Belen A1 - Fiedler, Susann A1 - Field, James G. A1 - Fitneva, Stanka A. A1 - Flagan, Taru A1 - Forest, Amanda L. A1 - Forsell, Eskil A1 - Foster, Joshua D. A1 - Frank, Michael C. A1 - Frazier, Rebecca S. A1 - Fuchs, Heather A1 - Gable, Philip A1 - Galak, Jeff A1 - Galliani, Elisa Maria A1 - Gampa, Anup A1 - Garcia, Sara A1 - Gazarian, Douglas A1 - Gilbert, Elizabeth A1 - Giner-Sorolla, Roger A1 - Glöckner, Andreas A1 - Göllner, Lars A1 - Goh, Jin X. A1 - Goldberg, Rebecca A1 - Goodbourn, Patrick T. A1 - Gordon-McKeon, Shauna A1 - Gorges, Bryan A1 - Gorges, Jessie A1 - Goss, Justin A1 - Graham, Jesse A1 - Grange, James A. A1 - Gray, Jeremy A1 - Hartgerink, Chris A1 - Hartshorne, Joshua A1 - Hasselman, Fred A1 - Hayes, Timothy A1 - Heikensten, Emma A1 - Henninger, Felix A1 - Hodsoll, John A1 - Holubar, Taylor A1 - Hoogendoorn, Gea A1 - Humphries, Denise J. A1 - Hung, Cathy O. -Y. A1 - Immelman, Nathali A1 - Irsik, Vanessa C. A1 - Jahn, Georg A1 - Jaekel, Frank A1 - Jekel, Marc A1 - Johannesson, Magnus A1 - Johnson, Larissa G. A1 - Johnson, David J. A1 - Johnson, Kate M. A1 - Johnston, William J. A1 - Jonas, Kai A1 - Joy-Gaba, Jennifer A. A1 - Kappes, Heather Barry A1 - Kelso, Kim A1 - Kidwell, Mallory C. A1 - Kim, Seung Kyung A1 - Kirkhart, Matthew A1 - Kleinberg, Bennett A1 - Knezevic, Goran A1 - Kolorz, Franziska Maria A1 - Kossakowski, Jolanda J. A1 - Krause, Robert Wilhelm A1 - Krijnen, Job A1 - Kuhlmann, Tim A1 - Kunkels, Yoram K. A1 - Kyc, Megan M. A1 - Lai, Calvin K. A1 - Laique, Aamir A1 - Lakens, Daniel A1 - Lane, Kristin A. A1 - Lassetter, Bethany A1 - Lazarevic, Ljiljana B. A1 - LeBel, Etienne P. A1 - Lee, Key Jung A1 - Lee, Minha A1 - Lemm, Kristi A1 - Levitan, Carmel A. A1 - Lewis, Melissa A1 - Lin, Lin A1 - Lin, Stephanie A1 - Lippold, Matthias A1 - Loureiro, Darren A1 - Luteijn, Ilse A1 - Mackinnon, Sean A1 - Mainard, Heather N. A1 - Marigold, Denise C. A1 - Martin, Daniel P. A1 - Martinez, Tylar A1 - Masicampo, E. J. A1 - Matacotta, Josh A1 - Mathur, Maya A1 - May, Michael A1 - Mechin, Nicole A1 - Mehta, Pranjal A1 - Meixner, Johannes A1 - Melinger, Alissa A1 - Miller, Jeremy K. A1 - Miller, Mallorie A1 - Moore, Katherine A1 - Möschl, Marcus A1 - Motyl, Matt A1 - Müller, Stephanie M. A1 - Munafo, Marcus A1 - Neijenhuijs, Koen I. A1 - Nervi, Taylor A1 - Nicolas, Gandalf A1 - Nilsonne, Gustav A1 - Nosek, Brian A. A1 - Nuijten, Michele B. A1 - Olsson, Catherine A1 - Osborne, Colleen A1 - Ostkamp, Lutz A1 - Pavel, Misha A1 - Penton-Voak, Ian S. A1 - Perna, Olivia A1 - Pernet, Cyril A1 - Perugini, Marco A1 - Pipitone, R. Nathan A1 - Pitts, Michael A1 - Plessow, Franziska A1 - Prenoveau, Jason M. A1 - Rahal, Rima-Maria A1 - Ratliff, Kate A. A1 - Reinhard, David A1 - Renkewitz, Frank A1 - Ricker, Ashley A. A1 - Rigney, Anastasia A1 - Rivers, Andrew M. A1 - Roebke, Mark A1 - Rutchick, Abraham M. A1 - Ryan, Robert S. A1 - Sahin, Onur A1 - Saide, Anondah A1 - Sandstrom, Gillian M. A1 - Santos, David A1 - Saxe, Rebecca A1 - Schlegelmilch, Rene A1 - Schmidt, Kathleen A1 - Scholz, Sabine A1 - Seibel, Larissa A1 - Selterman, Dylan Faulkner A1 - Shaki, Samuel A1 - Simpson, William B. A1 - Sinclair, H. Colleen A1 - Skorinko, Jeanine L. M. A1 - Slowik, Agnieszka A1 - Snyder, Joel S. A1 - Soderberg, Courtney A1 - Sonnleitner, Carina A1 - Spencer, Nick A1 - Spies, Jeffrey R. A1 - Steegen, Sara A1 - Stieger, Stefan A1 - Strohminger, Nina A1 - Sullivan, Gavin B. A1 - Talhelm, Thomas A1 - Tapia, Megan A1 - te Dorsthorst, Anniek A1 - Thomae, Manuela A1 - Thomas, Sarah L. A1 - Tio, Pia A1 - Traets, Frits A1 - Tsang, Steve A1 - Tuerlinckx, Francis A1 - Turchan, Paul A1 - Valasek, Milan A1 - Van Aert, Robbie A1 - van Assen, Marcel A1 - van Bork, Riet A1 - van de Ven, Mathijs A1 - van den Bergh, Don A1 - van der Hulst, Marije A1 - van Dooren, Roel A1 - van Doorn, Johnny A1 - van Renswoude, Daan R. A1 - van Rijn, Hedderik A1 - Vanpaemel, Wolf A1 - Echeverria, Alejandro Vasquez A1 - Vazquez, Melissa A1 - Velez, Natalia A1 - Vermue, Marieke A1 - Verschoor, Mark A1 - Vianello, Michelangelo A1 - Voracek, Martin A1 - Vuu, Gina A1 - Wagenmakers, Eric-Jan A1 - Weerdmeester, Joanneke A1 - Welsh, Ashlee A1 - Westgate, Erin C. A1 - Wissink, Joeri A1 - Wood, Michael A1 - Woods, Andy A1 - Wright, Emily A1 - Wu, Sining A1 - Zeelenberg, Marcel A1 - Zuni, Kellylynn T1 - Estimating the reproducibility of psychological science JF - Science N2 - Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams. Y1 - 2015 U6 - https://doi.org/10.1126/science.aac4716 SN - 1095-9203 SN - 0036-8075 VL - 349 IS - 6251 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Weilbacher, Peter Michael A1 - Monreal-Ibero, Ana A1 - Verhamme, Anne A1 - Sandin, Christer A1 - Steinmetz, Matthias A1 - Kollatschny, Wolfram A1 - Krajnovic, Davor A1 - Kamann, Sebastian A1 - Roth, Martin M. A1 - Erroz-Ferrer, Santiago A1 - Marino, Raffaella Anna A1 - Maseda, Michael V. A1 - Wendt, Martin A1 - Bacon, Roland A1 - Dreizler, Stefan A1 - Richard, Johan A1 - Wisotzki, Lutz T1 - Lyman-continuum leakage as dominant source of diffuse ionized gas in the Antennae galaxy JF - Astronomy and astrophysics : an international weekly journal N2 - The Antennae galaxy (NGC 4038/39) is the closest major interacting galaxy system and is therefore often studied as a merger prototype. We present the first comprehensive integral field spectroscopic dataset of this system, observed with the MUSE instrument at the ESO VLT. We cover the two regions in this system which exhibit recent star formation: the central galaxy interaction and a region near the tip of the southern tidal tail. In these fields, we detect H II regions and diffuse ionized gas to unprecedented depth. About 15% of the ionized gas was undetected by previous observing campaigns. This newly detected faint ionized gas is visible everywhere around the central merger, and shows filamentary structure. We estimate diffuse gas fractions of about 60% in the central field and 10% in the southern region. We are able to show that the southern region contains a significantly different population of H II regions, showing fainter luminosities. By comparing H II region luminosities with the HST catalog of young star clusters in the central field, we estimate that there is enough Lyman-continuum leakage in the merger to explain the amount of diffuse ionized gas that we detect. We compare the Lyman-continuum escape fraction of each H II region against emission line ratios that are sensitive to the ionization parameter. While we find no systematic trend between these properties, the most extreme line ratios seem to be strong indicators of density bounded ionization. Extrapolating the Lyman-continuum escape fractions to the southern region, we conclude that simply from the comparison of the young stellar populations to the ionized gas there is no need to invoke other ionization mechanisms than Lyman-continuum leaking H II regions for the diffuse ionized gas in the Antennae. KW - galaxies: interactions KW - galaxies: individual: NGC 4038, NGC 4039 KW - galaxies: ISM KW - ISM: structure KW - H II regions Y1 - 2018 U6 - https://doi.org/10.1051/0004-6361/201731669 SN - 1432-0746 VL - 611 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Krösche, Christian A1 - Crescenzi, Orlando A1 - Hoffbauer, Wilfried A1 - Jansen, Martin A1 - Napolitano, Alessandra A1 - Prota, Guiseppe A1 - Peter, Martin G. T1 - Synthesis of dopamines labelled with 13C in the alpha- or beta-side chain positions, and their application for structure studies on melanins by solid state NMR spectroscopy Y1 - 1994 ER - TY - GEN A1 - Lachmair, Martin A1 - Ruiz Fernandez, Susana A1 - Bury, Nils-Alexander A1 - Gerjets, Peter A1 - Fischer, Martin H. A1 - Bock, Otmar L. T1 - How body orientation affects concepts of space, time and valence BT - functional relevance of integrating sensorimotor experiences during word processing T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - The aim of the present study was to test the functional relevance of the spatial concepts UP or DOWN for words that use these concepts either literally (space) or metaphorically (time, valence). A functional relevance would imply a symmetrical relationship between the spatial concepts and words related to these concepts, showing that processing words activate the related spatial concepts on one hand, but also that an activation of the concepts will ease the retrieval of a related word on the other. For the latter, the rotation angle of participant's body position was manipulated either to an upright or a head-down tilted body position to activate the related spatial concept. Afterwards participants produced in a within-subject design previously memorized words of the concepts space, time and valence according to the pace of a metronome. All words were related either to the spatial concept UP or DOWN. The results including Bayesian analyses show (1) a significant interaction between body position and words using the concepts UP and DOWN literally, (2) a marginal significant interaction between body position and temporal words and (3) no effect between body position and valence words. However, post-hoc analyses suggest no difference between experiments. Thus, the authors concluded that integrating sensorimotor experiences is indeed of functional relevance for all three concepts of space, time and valence. However, the strength of this functional relevance depends on how close words are linked to mental concepts representing vertical space. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 505 KW - mental timeline KW - cognition KW - language KW - representation KW - hypothesis KW - mechanisms KW - future KW - flies KW - line KW - mind Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-410942 SN - 1866-8364 IS - 505 ER - TY - JOUR A1 - Soliveres, Santiago A1 - van der Plas, Fons A1 - Manning, Peter A1 - Prati, Daniel A1 - Gossner, Martin M. A1 - Renner, Swen C. A1 - Alt, Fabian A1 - Arndt, Hartmut A1 - Baumgartner, Vanessa A1 - Binkenstein, Julia A1 - Birkhofer, Klaus A1 - Blaser, Stefan A1 - Blüthgen, Nico A1 - Boch, Steffen A1 - Böhm, Stefan A1 - Börschig, Carmen A1 - Buscot, Francois A1 - Diekötter, Tim A1 - Heinze, Johannes A1 - Hölzel, Norbert A1 - Jung, Kirsten A1 - Klaus, Valentin H. A1 - Kleinebecker, Till A1 - Klemmer, Sandra A1 - Krauss, Jochen A1 - Lange, Markus A1 - Morris, E. Kathryn A1 - Müller, Jörg A1 - Oelmann, Yvonne A1 - Overmann, Jörg A1 - Pasalic, Esther A1 - Rillig, Matthias C. A1 - Schaefer, H. Martin A1 - Schloter, Michael A1 - Schmitt, Barbara A1 - Schöning, Ingo A1 - Schrumpf, Marion A1 - Sikorski, Johannes A1 - Socher, Stephanie A. A1 - Solly, Emily F. A1 - Sonnemann, Ilja A1 - Sorkau, Elisabeth A1 - Steckel, Juliane A1 - Steffan-Dewenter, Ingolf A1 - Stempfhuber, Barbara A1 - Tschapka, Marco A1 - Türke, Manfred A1 - Venter, Paul C. A1 - Weiner, Christiane N. A1 - Weisser, Wolfgang W. A1 - Werner, Michael A1 - Westphal, Catrin A1 - Wilcke, Wolfgang A1 - Wolters, Volkmar A1 - Wubet, Tesfaye A1 - Wurst, Susanne A1 - Fischer, Markus A1 - Allan, Eric T1 - Biodiversity at multiple trophic levels is needed for ecosystem multifunctionality JF - Nature : the international weekly journal of science Y1 - 2016 U6 - https://doi.org/10.1038/nature19092 SN - 0028-0836 SN - 1476-4687 VL - 536 SP - 456 EP - + PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Lachmair, Martin A1 - Fernandez, Susana Ruiz A1 - Bury, Nils-Alexander A1 - Gerjets, Peter A1 - Fischer, Martin H. A1 - Bock, Otmar L. T1 - How Body Orientation Affects Concepts of Space, Time and Valence: Functional Relevance of Integrating Sensorimotor Experiences during Word Processing JF - PLoS one Y1 - 2016 U6 - https://doi.org/10.1371/journal.pone.0165795 SN - 1932-6203 VL - 11 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Husser, Tim-Oliver A1 - Kamann, Sebastian A1 - Dreizler, Stefan A1 - Wendt, Martin A1 - Wulff, Nina A1 - Bacon, Roland A1 - Wisotzki, Lutz A1 - Brinchmann, Jarle A1 - Weilbacher, Peter Michael A1 - Roth, Martin M. A1 - Monreal-Ibero, Ana T1 - MUSE crowded field 3D spectroscopy of over 12 000 stars in the globular cluster NGC 6397 I. The first comprehensive HRD of a globular cluster JF - Nucleic acids research N2 - Aims. We demonstrate the high multiplex advantage of crowded field 3D spectroscopy with the new integral field spectrograph MUSE by means of a spectroscopic analysis of more than 12 000 individual stars in the globular cluster NGC 6397. Methods. The stars are deblended with a point spread function fitting technique, using a photometric reference catalogue from HST as prior, including relative positions and brightnesses. This catalogue is also used for a first analysis of the extracted spectra, followed by an automatic in-depth analysis via a full-spectrum fitting method based on a large grid of PHOENIX spectra. Results. We analysed the largest sample so far available for a single globular cluster of 18 932 spectra from 12 307 stars in NGC 6397. We derived a mean radial velocity of v(rad) = 17.84 +/- 0.07 km s(-1) and a mean metallicity of [Fe/H] = -2.120 +/- 0.002, with the latter seemingly varying with temperature for stars on the red giant branch (RGB). We determine Teff and [Fe/H] from the spectra, and log g from HST photometry. This is the first very comprehensive Hertzsprung-Russell diagram (HRD) for a globular cluster based on the analysis of several thousands of stellar spectra, ranging from the main sequence to the tip of the RGB. Furthermore, two interesting objects were identified; one is a post-AGB star and the other is a possible millisecond-pulsar companion. KW - methods: data analysis KW - techniques: imaging spectroscopy KW - planets and satellites: fundamental parameters KW - stars: atmospheres KW - pulsars: general KW - globular clusters: individual: NGC 6397 Y1 - 2016 U6 - https://doi.org/10.1051/0004-6361/201526949 SN - 1432-0746 VL - 588 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Herder, Martin A1 - Utecht, Manuel Martin A1 - Manicke, Nicole A1 - Grubert, Lutz A1 - Pätzel, Michael A1 - Saalfrank, Peter A1 - Hecht, Stefan T1 - Switching with orthogonal stimuli electrochemical ring-closure and photochemical ring-opening of bis(thiazolyl) maleimides JF - Chemical science N2 - The photochemistry as well as electrochemistry of novel donor-acceptor bis(morpholinothiazolyl)maleimides has been investigated. Proper substitution of these diarylethene-type molecular switches leads to the unique situation in which their ring-closure can only be accomplished electrochemically, while ring-opening can only be achieved photochemically. Hence, these switches operate with orthogonal stimuli, i.e. redox potential and light, respectively. The switch system could be optimized by introducing trifluoromethyl groups at the reactive carbon atoms in order to avoid by-product formation during oxidative ring closure. Both photochemical and electrochemical pathways were investigated for methylated, trifluoromethylated, and nonsymmetrical bis(morpholinothiazolyl) maleimides as well as the bis(morpholinothiazolyl) cyclopentene reference compound. With the aid of the nonsymmetrical "mixed" derivative, the mechanism of electrochemically driven ring closure could be elucidated and seems to proceed via a dicationic intermediate generated by two-fold oxidation. All experimental work has been complemented by density functional theory that provides detailed insights into the thermodynamics of the ring-open and closed forms, the nature of their excited states, and the reactivity of their neutral as well as ionized species in different electronic configurations. The particular diarylethene systems described herein could serve in multifunctional (logic) devices operated by different stimuli (inputs) and may pave the way to converting light into electrical energy via photoinduced "pumping" of redox-active meta-stable states. Y1 - 2013 U6 - https://doi.org/10.1039/c2sc21681g SN - 2041-6520 VL - 4 IS - 3 SP - 1028 EP - 1040 PB - Royal Society of Chemistry CY - Cambridge ER - TY - GEN A1 - Schulze, Michael A1 - Utecht, Manuel Martin A1 - Moldt, Thomas A1 - Przyrembel, Daniel A1 - Gahl, Cornelius A1 - Weinelt, Martin A1 - Saalfrank, Peter A1 - Tegeder, Petra T1 - Nonlinear optical response of photochromic azobenzene-functionalized self-assembled monolayers N2 - The combination of photochromic and nonlinear optical (NLO) properties of azobenzene-functionalized self-assembled monolayers (SAMs) constitutes an intriguing step towards novel photonic and optoelectronic devices. By utilizing the second-order NLO process of second harmonic generation (SHG), supported by density-functional theory and correlated wave function method calculations, we demonstrate that the photochromic interface provides the necessary prerequisites en route towards possible future technical applications: we find a high NLO contrast on the order of 16% between the switching states. These are furthermore accessible reversibly and with high efficiencies in terms of cross sections on the order of 10−18 cm2 for both photoisomerization reactions, i.e., drivable by means of low-power LED light sources. Finally, both photostationary states (PSSs) are thermally stable at ambient conditions. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 196 Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-81198 ER - TY - JOUR A1 - Luo, Ying A1 - Utecht, Manuel Martin A1 - Dokic, Jadranka A1 - Korchak, Sergey A1 - Vieth, Hans-Martin A1 - Haag, Rainer A1 - Saalfrank, Peter T1 - Cis-trans isomerisation of substituted aromatic imines a comparative experimental and theoretical study JF - ChemPhysChem : a European journal of chemical physics and physical chemistry N2 - The cis-trans isomerisation of N-benzylideneaniline (NBA) and derivatives containing a central C=N bond has been investigated experimentally and theoretically. Eight different NBA molecules in three different solvents were irradiated to enforce a photochemical trans (hv) -> cis isomerisation and the kinetics of the thermal backreaction cis (Delta)-> trans were determined by NMR spectroscopy measurements in the temperature range between 193 and 288 K. Theoretical calculations using density functional theory and Eyring transition-state theory were carried out for 12 different NBA species in the gas phase and three different solvents to compute thermal isomerisation rates of the thermal back reaction. While the computed absolute rates are too large, they reveal and explain experimental trends. Time-dependent density functional theory provides optical spectra for vertical transitions and excitation energy differences between trans and cis forms. Together with isomerisation rates, the latter can be used to identify "optimal switches" with good photochromicity and reasonable thermal stability. KW - density functional calculations KW - imines KW - isomerization KW - photochemistry KW - thermochemistry Y1 - 2011 U6 - https://doi.org/10.1002/cphc.201100179 SN - 1439-4235 VL - 12 IS - 12 SP - 2311 EP - 2321 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Schulze, Michael A1 - Utecht, Manuel Martin A1 - Moldt, Thomas A1 - Przyrembel, Daniel A1 - Gahl, Cornelius A1 - Weinelt, Martin A1 - Saalfrank, Peter A1 - Tegeder, Petra T1 - Nonlinear optical response of photochromic azobenzene-functionalized self-assembled monolayers JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - The combination of photochromic and nonlinear optical (NLO) properties of azobenzene-functionalized self-assembled monolayers (SAMs) constitutes an intriguing step towards novel photonic and optoelectronic devices. By utilizing the second-order NLO process of second harmonic generation (SHG), supported by density-functional theory and correlated wave function method calculations, we demonstrate that the photochromic interface provides the necessary prerequisites en route towards possible future technical applications: we find a high NLO contrast on the order of 16% between the switching states. These are furthermore accessible reversibly and with high efficiencies in terms of cross sections on the order of 10(-18) cm(2) for both photoisomerization reactions, i.e., drivable by means of low-power LED light sources. Finally, both photostationary states (PSSs) are thermally stable at ambient conditions. Y1 - 2015 U6 - https://doi.org/10.1039/c5cp03093e SN - 1463-9076 SN - 1463-9084 VL - 17 IS - 27 SP - 18079 EP - 18086 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Schulze, Michael A1 - Utecht, Manuel Martin A1 - Moldt, Thomas A1 - Przyrembel, Daniel A1 - Gahl, Cornelius A1 - Weinelt, Martin A1 - Saalfrank, Peter A1 - Tegeder, Petra T1 - Nonlinear optical response of photochromic azobenzene-functionalized self-assembled monolayers JF - Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies N2 - The combination of photochromic and nonlinear optical (NLO) properties of azobenzene-functionalized self-assembled monolayers (SAMs) constitutes an intriguing step towards novel photonic and optoelectronic devices. By utilizing the second-order NLO process of second harmonic generation (SHG), supported by density-functional theory and correlated wave function method calculations, we demonstrate that the photochromic interface provides the necessary prerequisites en route towards possible future technical applications: we find a high NLO contrast on the order of 16% between the switching states. These are furthermore accessible reversibly and with high efficiencies in terms of cross sections on the order of 10−18 cm2 for both photoisomerization reactions, i.e., drivable by means of low-power LED light sources. Finally, both photostationary states (PSSs) are thermally stable at ambient conditions. Y1 - 2015 U6 - https://doi.org/10.1039/c5cp03093e SN - 1463-9076 SN - 1463-9084 VL - 27 IS - 17 SP - 18079 EP - 18086 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Volk, Benno A1 - Markert, Doreen A1 - Riejok, Henriette A1 - Dittberner, Jürgen A1 - Wanka, Johanna A1 - Wilkens, Martin A1 - Görtemaker, Manfred A1 - Regierer, Babette A1 - Steup, Martin A1 - Müller-Röber, Bernd A1 - Wernicke, Matthias A1 - Altenberger, Uwe A1 - Stölting, Erhard A1 - Ferý, Carolin A1 - Egenter, Peter A1 - Lenz, Claudia A1 - Jakubowski, Zuzanna A1 - Klötzer, Sylvia A1 - Krause, Michael A1 - Dietsch, Ulrich T1 - Portal = Vor der Präsidenten-Wahl: Erwartungen, Wünsche, Vorschläge BT - Die Potsdamer Universitätszeitung N2 - Aus dem Inhalt: - Vor der Präsidenten-Wahl: Erwartungen, Wünsche, Vorschläge - Der AStA in der Krise? - Über Satire und Macht in der DDR - Vom Fünf-Sterne-Koch zum Mensaleiter T3 - Portal: Das Potsdamer Universitätsmagazin - 04-05/2006 Y1 - 2006 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440005 SN - 1618-6893 IS - 04-05/2006 ER - TY - GEN A1 - Abramowski, Attila A1 - Aharonian, Felix A. A1 - Benkhali, Faical Ait A1 - Akhperjanian, A. G. A1 - Angüner, Ekrem Oǧuzhan A1 - Backes, Michael A1 - Balenderan, Shangkari A1 - Balzer, Arnim A1 - Barnacka, Anna A1 - Becherini, Yvonne A1 - Tjus, Julia Becker A1 - Berge, David A1 - Bernhard, Sabrina A1 - Bernlöhr, Konrad A1 - Birsin, E. A1 - Biteau, Jonathan A1 - Böttcher, Markus A1 - Boisson, Catherine A1 - Bolmont, J. A1 - Bordas, Pol A1 - Bregeon, Johan A1 - Brun, Francois A1 - Brun, Pierre A1 - Bryan, Mark A1 - Bulik, Tomasz A1 - Carrigan, Svenja A1 - Casanova, Sabrina A1 - Chadwick, Paula M. A1 - Chakraborty, Nachiketa A1 - Chalme-Calvet, R. A1 - Chaves, Ryan C. G. A1 - Chretien, M. A1 - Colafrancesco, Sergio A1 - Cologna, Gabriele A1 - Conrad, Jan A1 - Couturier, Claire A1 - Cui, Yudong A1 - Davids, Isak Delberth A1 - Degrange, Bernhard A1 - Deil, Christoph A1 - deWilt, P. A1 - Djannati-Ataï, A. A1 - Domainko, Wilfried A1 - Donath, Axel A1 - Dubus, G. A1 - Dutson, K. A1 - Dyks, J. A1 - Dyrda, M. A1 - Edwards, Tanya A1 - Egberts, Kathrin A1 - Eger, Peter A1 - Espigat, P. A1 - Farnier, C. A1 - Fegan, Stephen A1 - Feinstein, Fabrice A1 - Fernandes, Milton Virgilio A1 - Fernandez, Diane A1 - Fiasson, A. A1 - Fontaine, Gerard A1 - Förster, Andreas A1 - Fuessling, M. A1 - Gabici, S. A1 - Gajdus, M. A1 - Gallant, Yves A. A1 - Garrigoux, Tania A1 - Giavitto, G. A1 - Giebels, Berrie A1 - Glicenstein, Jean-Francois A1 - Gottschall, Daniel A1 - Grondin, M. -H. A1 - Grudzinska, M. A1 - Hadasch, Daniela A1 - Haeffner, S. A1 - Hahn, Joachim A1 - Harris, Jonathan A1 - Heinzelmann, Götz A1 - Henri, G. A1 - Hermann, German A1 - Hervet, O. A1 - Hillert, Andreas A1 - Hinton, James Anthony A1 - Hofmann, Werner A1 - Hofverberg, Petter A1 - Holler, Markus A1 - Horns, Dieter A1 - Ivascenko, Alex A1 - Jacholkowska, A. A1 - Jahn, C. A1 - Jamrozy, Marek A1 - Janiak, M. A1 - Jankowsky, F. A1 - Jung-Richardt, I. A1 - Kastendieck, Max Anton A1 - Katarzynski, K. A1 - Katz, U. A1 - Kaufmann, S. A1 - Khelifi, B. A1 - Kieffer, Michel A1 - Klepser, S. A1 - Klochkov, Dmitry A1 - Kluzniak, W. A1 - Kolitzus, David A1 - Komin, Nu A1 - Kosack, Karl A1 - Krakau, Steffen A1 - Krayzel, F. A1 - Krueger, Pat P. A1 - Laffon, H. A1 - Lamanna, G. A1 - Lefaucheur, J. A1 - Lefranc, Valentin A1 - Lemiere, A. A1 - Lemoine-Goumard, M. A1 - Lenain, J. -P. A1 - Lohse, Thomas A1 - Lopatin, A. A1 - Lu, Chia-Chun A1 - Marandon, Vincent A1 - Marcowith, Alexandre A1 - Marx, Ramin A1 - Maurin, G. A1 - Maxted, Nigel A1 - Mayer, Michael A1 - McComb, T. J. Lowry A1 - Mehault, J. A1 - Meintjes, P. J. A1 - Menzler, Ulf A1 - Meyer, M. A1 - Mitchell, Alison M. W. A1 - Moderski, R. A1 - Mohamed, M. A1 - Mora, K. A1 - Moulin, Emmanuel A1 - Murach, Thomas A1 - de Naurois, Mathieu A1 - Niemiec, J. A1 - Nolan, Sam J. A1 - Oakes, Louise A1 - Odaka, Hirokazu A1 - Ohm, S. A1 - Optiz, Björn A1 - Ostrowski, Michal A1 - Oya, I. A1 - Panter, Michael A1 - Parsons, R. Daniel A1 - Arribas, M. Paz A1 - Pekeur, Nikki W. A1 - Pelletier, G. A1 - Petrucci, P. -O. A1 - Peyaud, B. A1 - Pita, S. A1 - Poon, Helen A1 - Pühlhofer, Gerd A1 - Punch, M. A1 - Quirrenbach, A. A1 - Raab, S. A1 - Reichardt, I. A1 - Reimer, Anita A1 - Reimer, Olaf A1 - Renaud, Metz A1 - de los Reyes, Raquel A1 - Rieger, Frank A1 - Romoli, C. A1 - Rosier-Lees, S. A1 - Rowell, G. A1 - Rudak, B. A1 - Rulten, C. B. A1 - Sahakian, Vardan A1 - Salek, D. A1 - Sanchez, David M. A1 - Santangelo, Andrea A1 - Schlickeiser, Reinhard A1 - Schuessler, F. A1 - Schulz, A. A1 - Schwanke, Ullrich A1 - Schwarzburg, S. A1 - Schwemmer, S. A1 - Sol, H. A1 - Spanier, Felix A1 - Spengler, G. A1 - Spies, Franziska A1 - Stawarz, Lukasz A1 - Steenkamp, Riaan A1 - Stegmann, Christian A1 - Stinzing, F. A1 - Stycz, K. A1 - Sushch, Iurii A1 - Tavernet, J. -P. A1 - Tavernier, T. A1 - Taylor, A. M. A1 - Terrier, R. A1 - Tluczykont, Martin A1 - Trichard, C. A1 - Valerius, K. A1 - van Eldik, C. A1 - van Soelen, B. A1 - Vasileiadis, Georges A1 - Veh, J. A1 - Venter, Christo A1 - Viana, Aion A1 - Vincent, P. A1 - Vink, Jacco A1 - Völk, Heinrich J. A1 - Volpe, Francesca A1 - Vorster, Martine A1 - Vuillaume, T. A1 - Wagner, S. J. A1 - Wagner, P. A1 - Wagner, R. M. A1 - Ward, Martin A1 - Weidinger, Matthias A1 - Weitzel, Quirin A1 - White, R. A1 - Wierzcholska, A. A1 - Willmann, P. A1 - Woernlein, A. A1 - Wouters, D. A1 - Yang, Ruizhi A1 - Zabalza, Victor A1 - Zaborov, Dmitry A1 - Zacharias, M. A1 - Zdziarski, A. A. A1 - Zech, Alraune A1 - Zechlin, Hannes -S. T1 - H.E.S.S. detection of TeV emission from the interaction region between the supernova remnant G349.7+0.2 and a molecular cloud (vol 574, A100, 2015) T2 - Astronomy and astrophysics : an international weekly journal KW - gamma rays: general KW - ISM: supernova remnants KW - ISM: clouds KW - errata, addenda Y1 - 2015 U6 - https://doi.org/10.1051/0004-6361/201425070e SN - 1432-0746 VL - 580 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Soliveres, Santiago A1 - Manning, Peter A1 - Prati, Daniel A1 - Gossner, Martin M. A1 - Alt, Fabian A1 - Arndt, Hartmut A1 - Baumgartner, Vanessa A1 - Binkenstein, Julia A1 - Birkhofer, Klaus A1 - Blaser, Stefan A1 - Bluethgen, Nico A1 - Boch, Steffen A1 - Boehm, Stefan A1 - Boerschig, Carmen A1 - Buscot, Francois A1 - Diekoetter, Tim A1 - Heinze, Johannes A1 - Hoelzel, Norbert A1 - Jung, Kirsten A1 - Klaus, Valentin H. A1 - Klein, Alexandra-Maria A1 - Kleinebecker, Till A1 - Klemmer, Sandra A1 - Krauss, Jochen A1 - Lange, Markus A1 - Morris, E. Kathryn A1 - Mueller, Joerg A1 - Oelmann, Yvonne A1 - Overmann, Jörg A1 - Pasalic, Esther A1 - Renner, Swen C. A1 - Rillig, Matthias C. A1 - Schaefer, H. Martin A1 - Schloter, Michael A1 - Schmitt, Barbara A1 - Schoening, Ingo A1 - Schrumpf, Marion A1 - Sikorski, Johannes A1 - Socher, Stephanie A. A1 - Solly, Emily F. A1 - Sonnemann, Ilja A1 - Sorkau, Elisabeth A1 - Steckel, Juliane A1 - Steffan-Dewenter, Ingolf A1 - Stempfhuber, Barbara A1 - Tschapka, Marco A1 - Tuerke, Manfred A1 - Venter, Paul A1 - Weiner, Christiane N. A1 - Weisser, Wolfgang W. A1 - Werner, Michael A1 - Westphal, Catrin A1 - Wilcke, Wolfgang A1 - Wolters, Volkmar A1 - Wubet, Tesfaye A1 - Wurst, Susanne A1 - Fischer, Markus A1 - Allan, Eric T1 - Locally rare species influence grassland ecosystem multifunctionality JF - Philosophical transactions of the Royal Society of London : B, Biological sciences N2 - Species diversity promotes the delivery of multiple ecosystem functions (multifunctionality). However, the relative functional importance of rare and common species in driving the biodiversity multifunctionality relationship remains unknown. We studied the relationship between the diversity of rare and common species (according to their local abundances and across nine different trophic groups), and multifunctionality indices derived from 14 ecosystem functions on 150 grasslands across a land use intensity (LUI) gradient. The diversity of above- and below-ground rare species had opposite effects, with rare above-ground species being associated with high levels of multifunctionality, probably because their effects on different functions did not trade off against each other. Conversely, common species were only related to average, not high, levels of multifunctionality, and their functional effects declined with LUI. Apart from the community level effects of diversity, we found significant positive associations between the abundance of individual species and multifunctionality in 6% of the species tested. Species specific functional effects were best predicted by their response to LUI: species that declined in abundance with land use intensification were those associated with higher levels of multifunctionality. Our results highlight the importance of rare species for ecosystem multifunctionality and help guiding future conservation priorities. KW - biodiversity KW - common species KW - ecosystem function KW - identity hypothesis KW - land use KW - multitrophic Y1 - 2016 U6 - https://doi.org/10.1098/rstb.2015.0269 SN - 0962-8436 SN - 1471-2970 VL - 371 SP - 3175 EP - 3185 PB - Royal Society CY - London ER - TY - JOUR A1 - Allan, Eric A1 - Bossdorf, Oliver A1 - Dormann, Carsten F. A1 - Prati, Daniel A1 - Gossner, Martin M. A1 - Tscharntke, Teja A1 - Blüthgen, Nico A1 - Bellach, Michaela A1 - Birkhofer, Klaus A1 - Boch, Steffen A1 - Böhm, Stefan A1 - Börschig, Carmen A1 - Chatzinotas, Antonis A1 - Christ, Sabina A1 - Daniel, Rolf A1 - Diekötter, Tim A1 - Fischer, Christiane A1 - Friedl, Thomas A1 - Glaser, Karin A1 - Hallmann, Christine A1 - Hodac, Ladislav A1 - Hölzel, Norbert A1 - Jung, Kirsten A1 - Klein, Alexandra-Maria A1 - Klaus, Valentin H. A1 - Kleinebecker, Till A1 - Krauss, Jochen A1 - Lange, Markus A1 - Morris, E. Kathryn A1 - Müller, Jörg A1 - Nacke, Heiko A1 - Pasalic, Esther A1 - Rillig, Matthias C. A1 - Rothenwoehrer, Christoph A1 - Schally, Peter A1 - Scherber, Christoph A1 - Schulze, Waltraud X. A1 - Socher, Stephanie A. A1 - Steckel, Juliane A1 - Steffan-Dewenter, Ingolf A1 - Türke, Manfred A1 - Weiner, Christiane N. A1 - Werner, Michael A1 - Westphal, Catrin A1 - Wolters, Volkmar A1 - Wubet, Tesfaye A1 - Gockel, Sonja A1 - Gorke, Martin A1 - Hemp, Andreas A1 - Renner, Swen C. A1 - Schöning, Ingo A1 - Pfeiffer, Simone A1 - König-Ries, Birgitta A1 - Buscot, Francois A1 - Linsenmair, Karl Eduard A1 - Schulze, Ernst-Detlef A1 - Weisser, Wolfgang W. A1 - Fischer, Markus T1 - Interannual variation in land-use intensity enhances grassland multidiversity JF - Proceedings of the National Academy of Sciences of the United States of America N2 - Although temporal heterogeneity is a well-accepted driver of biodiversity, effects of interannual variation in land-use intensity (LUI) have not been addressed yet. Additionally, responses to land use can differ greatly among different organisms; therefore, overall effects of land-use on total local biodiversity are hardly known. To test for effects of LUI (quantified as the combined intensity of fertilization, grazing, and mowing) and interannual variation in LUI (SD in LUI across time), we introduce a unique measure of whole-ecosystem biodiversity, multidiversity. This synthesizes individual diversity measures across up to 49 taxonomic groups of plants, animals, fungi, and bacteria from 150 grasslands. Multidiversity declined with increasing LUI among grasslands, particularly for rarer species and aboveground organisms, whereas common species and belowground groups were less sensitive. However, a high level of interannual variation in LUI increased overall multidiversity at low LUI and was even more beneficial for rarer species because it slowed the rate at which the multidiversity of rare species declined with increasing LUI. In more intensively managed grasslands, the diversity of rarer species was, on average, 18% of the maximum diversity across all grasslands when LUI was static over time but increased to 31% of the maximum when LUI changed maximally over time. In addition to decreasing overall LUI, we suggest varying LUI across years as a complementary strategy to promote biodiversity conservation. KW - biodiversity loss KW - agricultural grasslands KW - Biodiversity Exploratories Y1 - 2014 U6 - https://doi.org/10.1073/pnas.1312213111 SN - 0027-8424 VL - 111 IS - 1 SP - 308 EP - 313 PB - National Acad. of Sciences CY - Washington ER - TY - JOUR A1 - Schroetter, Ilane A1 - Bouche, Nicolas F. A1 - Zabl, Johannes A1 - Contini, Thierry A1 - Wendt, Martin A1 - Schaye, Joop A1 - Mitchell, Peter A1 - Muzahid, Sowgat A1 - Marino, Raffaella Anna A1 - Bacon, Roland A1 - Lilly, Simon J. A1 - Richard, Johan A1 - Wisotzki, Lutz T1 - MusE GAs FLOw andWind (MEGAFLOW) BT - III. Galactic wind properties using background quasars JF - Monthly notices of the Royal Astronomical Society N2 - We present results from our on-going MusE GAs FLOw and Wind (MEGAFLOW) survey, which consists of 22 quasar lines of sight, each observed with the integral field unit MUSE and the UVES spectrograph at the ESO Very Large Telescopes (VLT). The goals of this survey are to study the properties of the circumgalactic medium around z similar to 1 star-forming galaxies. The absorption-line selected survey consists of 79 strong MgII absorbers (with rest-frame equivalent width greater than or similar to 0.3 angstrom) and, currently, 86 associated galaxies within 100 projected kpc of the quasar with stellar masses (M-star) from 109 to 1011 M-circle dot. We find that the cool halo gas traced by MgII is not isotropically distributed around these galaxies from the strong bi-modal distribution in the azimuthal angle of the apparent location of the quasar with respect to the galaxy major axis. This supports a scenario in which outflows are bi-conical in nature and co-exist with a co-planar gaseous structure extending at least up to 60-80 kpc. Assuming that absorbers near the minor axis probe outflows, the current MEGAFLOW sample allowed us to select 26 galaxy-quasar pairs suitable for studying winds. From this sample, using a simple geometrical model, we find that the outflow velocity only exceeds the escape velocity when M-star less than or similar to 4 x 10(9) M-circle dot, implying the cool material is likely to fall back except in the smallest haloes. Finally, we find that the mass loading factor., the ratio between the ejected mass rate and the star formation rate, appears to be roughly constant with respect to the galaxy mass. KW - galaxies: evolution KW - galaxies: formation KW - intergalactic medium KW - quasars: absorption lines Y1 - 2019 U6 - https://doi.org/10.1093/mnras/stz2822 SN - 0035-8711 SN - 1365-2966 VL - 490 IS - 3 SP - 4368 EP - 4381 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Latour, Marlyn A1 - Husser, Tim Oliver A1 - Giesers, Benjamin David A1 - Kamann, S. A1 - Göttgens, Fabian A1 - Dreizler, Stefan A1 - Brinchmann, Jan A1 - Bastian, Nate A1 - Wendt, Martin A1 - Weilbacher, Peter Michael A1 - Molinski, N. S. T1 - A stellar census in globular clusters with MUSE: multiple populations chemistry in NGC 2808 star star star JF - Astronomy and astrophysics : an international weekly journal N2 - Context. Galactic globular clusters (GCs) are now known to host multiple populations displaying particular abundance variations. The different populations within a GC can be well distinguished following their position in the pseudo two-colors diagrams, also referred to as "chromosome maps". These maps are constructed using optical and near-UV photometry available from the Hubble Space Telescope (HST) UV survey of GCs. However, the chemical tagging of the various populations in the chromosome maps is hampered by the fact that HST photometry and elemental abundances are both only available for a limited number of stars. Aims. The spectra collected as part of the MUSE survey of globular clusters provide a spectroscopic counterpart to the HST photometric catalogs covering the central regions of GCs. In this paper, we use the MUSE spectra of 1115 red giant branch (RGB) stars in NGC 2808 to characterize the abundance variations seen in the multiple populations of this cluster. Methods. We used the chromosome map of NGC 2808 to divide the RGB stars into their respective populations. We then combined the spectra of all stars belonging to a given population, resulting in one high signal-to-noise ratio spectrum representative of each population. Results. Variations in the spectral lines of O, Na, Mg, and Al are clearly detected among four of the populations. In order to quantify these variations, we measured equivalent width differences and created synthetic populations spectra that were used to determine abundance variations with respect to the primordial population of the cluster. Our results are in good agreement with the values expected from previous studies based on high-resolution spectroscopy. We do not see any significant variations in the spectral lines of Ca, K, and Ba. We also do not detect abundance variations among the stars belonging to the primordial population of NGC 2808. Conclusions. We demonstrate that in spite of their low resolution, the MUSE spectra can be used to investigate abundance variations in the context of multiple populations. KW - techniques: imaging spectroscopy KW - stars: abundances KW - globular clusters: individual: NGC 2808 Y1 - 2019 U6 - https://doi.org/10.1051/0004-6361/201936242 SN - 1432-0746 VL - 631 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Wunder, Bernd A1 - Kutzschbach, Martin A1 - Hosse, Luisa A1 - Wilke, Franziska Daniela Helena A1 - Schertl, Hans-Peter A1 - Chopin, Christian T1 - Synthetic B-[4]-bearing dumortierite and natural B-[4]-free magnesiodumortierite from the Dora-Maira Massif BT - differences in boron coordination in response to ultrahigh pressure JF - European journal of mineralogy N2 - Dumortierite was synthesized in piston-cylinder experiments at 2.5-4.0 GPa, 650-700 degrees C in the Al2O3 -B2O3-SiO2-H2O (ABSH) system. Electron-microprobe (EMP) analyses reveal significant boron-excess (up to 0.26 B-[4] per formula unit, pfu) and silicon-deficiency relative to the ideal anhydrous dumortierite stoichiometry Al7BSi3O18 . The EMP data in conjunction with results from single-crystal Raman spectroscopy and powder X-ray diffraction provide evidence that silicon at the tetrahedral site is replaced by excess boron via the substitution Si-[4] <--> B-[4] + H. The Raman spectrum of synthetic dumortierite in the frequency region 2000 4000 cm(-1) comprises eight bands, of which six are located at frequencies below 3400 cm(-1). This points to strong hydrogen bonding, most likely O2-H center dot center dot center dot O7 and O7-H center dot center dot center dot O2, arising from a high number of octahedral vacancies at the All site and substitution of trivalent Al3+ and B3+ for Si4+ at Si1 and Si2 sites, causing decreasing acceptor-donor distances and lower incident valence at the acceptor oxygen. Contrary to the synthetic high-pressure ABSH-dumortierite, magnesiodumortierite from the Dora-Maira Massif, which is assumed to have formed at similar conditions (2.5-3.0 GPa, 700 degrees C), does not show any B-excess. Tourmaline shows an analogous behaviour in that magnesium-rich (e.g., dravitic) tourmaline formed at high pressure shows no or only minor amounts of tetrahedral boron, whereas natural aluminum-rich tourmaline and synthetic olenitic tourmaline formed at high pressures can incorporate significant amounts of tetrahedral boron. Two mechanisms might account for this discrepancy: (i) Structural avoidance of Mg-[6]-(OR3+)-R-[4] configurations in magnesiodumortierite due to charge deficieny at the oxygens O2 and O7 and strong local distortion of M1 due to decreased O2-O7 bond length, and/or (ii) decreasing fluid mobility of boron in Al-rich systems at high pressures. KW - dumortierite KW - magnesiodumortierite KW - Dora-Maira KW - ultrahigh-pressure (UHP) KW - ABSH-system KW - synthesis KW - tetrahedral boron KW - Raman spectroscopy Y1 - 2018 U6 - https://doi.org/10.1127/ejm/2018/0030-2742 SN - 0935-1221 SN - 1617-4011 VL - 30 IS - 3 SP - 471 EP - 483 PB - Schweizerbart CY - Stuttgart ER - TY - JOUR A1 - Monreal-Ibero, Ana A1 - Weilbacher, Peter Michael A1 - Wendt, Martin T1 - Diffuse interstellar bands lambda 5780 and lambda 5797 in the Antennae Galaxy as seen by MUSE JF - Astronomy and astrophysics : an international weekly journal N2 - Context. Diffuse interstellar bands (DIBs) are faint spectral absorption features of unknown origin. Research on DIBs beyond the Local Group is very limited and will surely blossom in the era of the Extremely Large Telescopes. However, we can already start paving the way. One possibility that needs to be explored is the use of high-sensitivity integral field spectrographs. Aims. Our goals are twofold. First, we aim to derive reliable mapping of at least one DIB in a galaxy outside the Local Group. Second, we want to explore the relation between DIBs and other properties of the interstellar medium (ISM) in the galaxy. Methods. We use Multi Unit Spectroscopic Explorer (MUSE) data for the Antennae Galaxy, the closest major galaxy merger. High signal-to-noise spectra were created by co-adding the signal of many spatial elements with the Voronoi binning technique. The emission of the underlying stellar population was modelled and substracted with the STARLIGHT spectral synthesis code. Flux and equivalent width of the features of interest were measured by means of fitting to Gaussian functions. Conclusions. The results illustrate the enormous potential of integral field spectrographs for extragalactic DIB research. KW - dust, extinction KW - ISM: lines and bands KW - galaxies: ISM KW - galaxies: individual: Antennae Galaxy KW - galaxies: interactions KW - ISM: structure Y1 - 2018 U6 - https://doi.org/10.1051/0004-6361/201732178 SN - 1432-0746 VL - 615 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Kutzschbach, Martin A1 - Guttmann, Peter A1 - Marquardt, K. A1 - Werner, S. A1 - Henzler, K. D. A1 - Wilke, Max T1 - A transmission x-ray microscopy and NEXAFS approach for studying corroded silicate glasses at the nanometre scale JF - European journal of glass science and technology / Deutsche Glastechnische Gesellschaft (DGG) and the Society of Glass Technology (SGT). B, Physics and chemistry of glasses N2 - In this study transmission X-ray microscopy (TXM) was tested as a method to investigate the chemistry and structure of corroded silicate glasses at the nanometer scale. Three different silicate glasses were altered in static corrosion experiments for 1-336 hours at temperatures between 60 degrees C and 85 degrees C using a 25% HCl solution. Thin lamellas were cut perpendicular to the surface of corroded glass monoliths and were analysed with conventional TEM as well as with TXM. By recording optical density profiles at photon energies around the Na and O K-edges, the shape of the corrosion rim/pristine glass interfaces and the thickness of the corrosion rims has been determined. Na and O near-edge X-ray absorption fine-structure spectra (NEXAFS) were obtained without inducing irradiation damage and have been used to detect chemical changes in the corrosion rims. Spatially resolved NEXAFS spectra at the O K-edge provided insight to structural changes in the corrosion layer on the atomic scale. By comparison to O K-edge spectra of silicate minerals and (hydrous) albite glass as well as to O K-edge NEXAFS of model structures simulated with ab initio calculations, evidence is provided that changes of the fine structure at the O K-edge are assigned to the formation of siloxane groups in the corrosion rim. Y1 - 2018 U6 - https://doi.org/10.13036/17533562.59.1.043 SN - 1753-3562 VL - 59 IS - 1 SP - 11 EP - 26 PB - Society of Glass Technology CY - Sheffield ER - TY - JOUR A1 - Nickerson, David A1 - Atalag, Koray A1 - de Bono, Bernard A1 - Geiger, Joerg A1 - Goble, Carole A1 - Hollmann, Susanne A1 - Lonien, Joachim A1 - Mueller, Wolfgang A1 - Regierer, Babette A1 - Stanford, Natalie J. A1 - Golebiewski, Martin A1 - Hunter, Peter T1 - The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable JF - Interface focus N2 - Reconstructing and understanding the Human Physiome virtually is a complex mathematical problem, and a highly demanding computational challenge. Mathematical models spanning from the molecular level through to whole populations of individuals must be integrated, then personalized. This requires interoperability with multiple disparate and geographically separated data sources, and myriad computational software tools. Extracting and producing knowledge from such sources, even when the databases and software are readily available, is a challenging task. Despite the difficulties, researchers must frequently perform these tasks so that available knowledge can be continually integrated into the common framework required to realize the Human Physiome. Software and infrastructures that support the communities that generate these, together with their underlying standards to format, describe and interlink the corresponding data and computer models, are pivotal to the Human Physiome being realized. They provide the foundations for integrating, exchanging and re-using data and models efficiently, and correctly, while also supporting the dissemination of growing knowledge in these forms. In this paper, we explore the standards, software tooling, repositories and infrastructures that support this work, and detail what makes them vital to realizing the Human Physiome. KW - Human Physiome KW - standards KW - repositories KW - service infrastructure KW - reproducible science KW - managing big data Y1 - 2016 U6 - https://doi.org/10.1098/rsfs.2015.0103 SN - 2042-8898 SN - 2042-8901 VL - 6 SP - 57 EP - 61 PB - Royal Society CY - London ER - TY - BOOK A1 - Frieß, Nina A1 - Lenz, Gunnar A1 - Martin, Erik A1 - Antošíková, Lucie A1 - Bainczyk-Crescentini, Marlene A1 - Chkhaidze, Elena A1 - Gladis, Lea A1 - Stickel, Hanna A1 - Kohl, Philipp A1 - Kowollik, Eva A1 - Matijević, Tijana A1 - Schimsheimer, Christof A1 - Simić, Dijana A1 - Sulikowska-Fajfer, Joanna A1 - Zalkowski, Olesia A1 - Ananka, Yaraslava A1 - Blum, Bianca Edith A1 - Färber, Christina A1 - Gorfinkel, Olga A1 - Hoy, Therese A1 - Reinecke, Willi A1 - Salden, Peter A1 - Schmitt, Angelika ED - Frieß, Nina ED - Lenz, Gunnar ED - Martin, Erik T1 - Grenzräume – Grenzbewegungen BT - Ergebnisse der Arbeitstreffen des Jungen Forums Slavistische Literaturwissenschaft in Basel 2013 und Frankfurt (Oder) und Słubice 2014 ; Bd. 1 N2 - Der vorliegende Sammelband vereinigt die Beiträge der 12. und 13. Tagung des Jungen Forums Slavistische Literaturwissenschaft (JFSL) in Basel 2013 und Frankfurt (Oder) und Słubice 2014. Unter den thematischen Leitbegriffen Grenzräume – Grenzbewegungen präsentiert er Einblicke in die Arbeit von Nachwuchswissenschaftlerinnen und -wissenschaftlern der deutsch­sprachigen slavischen Literatur- und Kulturwissenschaft. N2 - This anthology contains the contributions of the 12th and 13th JFSL meeting in Basel in 2013 and Frankfurt (Oder) and Słubice 2014, respectively. Under the topic Boundaries in Space — Boundaries in Motion it presents an insight into the work of young researchers of Slavic literature and culture studies. KW - Slavistik KW - Grenzen KW - Gender KW - Performanz KW - Postkolonial KW - Slavic studies KW - Borders KW - Gender KW - Performance KW - Postcolonial Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-86769 SN - 978-3-86956-358-9 IS - 1 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - BOOK A1 - Heimann, Heinz-Dieter A1 - Neitmann, Klaus A1 - Schich, Winfried A1 - Bauch, Martin A1 - Franke, Ellen A1 - Gahlbeck, Christian A1 - Popp, Christian A1 - Riedel, Peter T1 - Brandenburgisches Klosterbuch : Handbuch der Klöster, Stifte und Kommenden bis zur Mitte des 16. Jahrhunderts T3 - Brandenburgische Historische Studien Y1 - 2007 SN - 978-3-937233-26-0 VL - 14 PB - be.bra Wiss. Verl. CY - Berlin ER - TY - JOUR A1 - Ostermeyer, Martin A1 - Mudge, Damien A1 - Veitch, Peter John A1 - Munch, Jesper T1 - Thermally induced birefringence in Nd : YAG slab lasers N2 - We study thermally induced birefringence in crystalline Nd:YAG zigzag slab lasers and the associated depolarization losses. The optimum crystallographic orientation of the zigzag slab within the Nd:YAG boule and photoelastic effects in crystalline Nd:YAG slabs are briefly discussed. The depolarization is evaluated using the temperature and stress distributions, calculated using a finite element model, for realistically pumped and cooled slabs of finite dimensions. Jones matrices are then used to calculate the depolarization of the zigzag laser mode. We compare the predictions with measurements of depolarization, and suggest useful criteria for the design of the gain media for such lasers. Y1 - 2006 UR - http://www.opticsinfobase.org/ U6 - https://doi.org/10.1364/AO.45.005368 ER - TY - JOUR A1 - Peikow, Dirk A1 - Matern, Christa-Maria A1 - Peter, Martin G. A1 - Schilde, Uwe T1 - Crystal structure of (1,4,7,10,13-pentaoxacyclopentadecane-O,O ',O '',O ''')(trifluoromethanesulfonato-O,O ')sodium, Na(C10H20O5)(CF3SO3) N2 - C11H20F3NaO8S, monoclinic, P121/nil (no. 11), a = 7.947(1) angstrom, b = 12.056(1) angstrom, c = 9.083(1) angstrom, P = 106.01 (1)degrees, V = 836.4 angstrom(3), Z = 2, R-gt(F) = 0.043, wR(ref)(F-2) = 0.120, T = 210 K. Y1 - 2005 ER - TY - JOUR A1 - Alarcon, Julio A1 - Alderete, Joel B. A1 - Aguila, Sergio A1 - Peter, Martin G. T1 - Regio and stereoselective hydroxylation of alpha-agarofuran by biotransformation of rhizopus nigricans N2 - A new synthesis of 9 alpha-hydroxy-alpha-agarofuran (6 alpha) is described, using a microbiological hydroxylation alpha-agarofuran (5) as the key reaction. The stereochemistry of the biohydroxylation was determined on the basis of a NOESY-experiment and GIAO calculations at the B3LYP/cc-pVDZ level. A strong gamma-effect was observed at C15 of the agarofuran ring which was correctly predicted by the GIAO-B3LYP calculations Y1 - 2005 ER - TY - JOUR A1 - Fotie, J. A1 - Nkengfack, A. E. A1 - Peter, Martin G. A1 - Heydenreich, Matthias A1 - Fomum, Z. T. T1 - Chemical constituents of the ethyl acetate extracts of the stem bark and fruits of Dichrostachys cinerea and the roots of Parkia bicolor N2 - The antibacterial activities of ethyl acetate, methanol and aqueous extracts of the stem bark of Dichrostachys cinerea and the roots of Parkia bicolor have been evaluated. Ethyl acetate extracts have been investigated, studies that led to a series of known compounds, amongst which many are reported here for the very first time from both the species Y1 - 2004 SN - 1011-3924 ER - TY - JOUR A1 - Berth, Gisela A1 - Dautzenberg, Herbert A1 - Peter, Martin G. T1 - Physica-chemical characterization of chitosans in dilute solution Y1 - 1998 SN - 2-907922-57-2 ER - TY - JOUR A1 - Vaaje-Kolstad, G. A1 - Vasella, A. A1 - Peter, Martin G. A1 - Netter, C. A1 - Houston, Douglas R. A1 - Westereng, B. A1 - Synstad, Bjoenar A1 - Eijsink, Vincent G. H. A1 - van Aalten, Daan M. F. T1 - Interactions of a family 18 chitinase with the designed inhibitor HM508 and its degradation product, chitobiono- delta-lactone N2 - We describe enzymological and structural analyses of the interaction between the family 18 chitinase ChiB from Serratia marcescens and the designed inhibitor N,N'-diacetylchitobionoxime-N-phenylcarbamate (HM508). HM508 acts as a competitive inhibitor of this enzyme with a K-i in the 50 muM range. Active site mutants of ChiB show K-i values ranging from 1 to 200 muM, providing insight into some of the interactions that determine inhibitor affinity. Interestingly, the wild type enzyme slowly degrades HM508, but the inhibitor is essentially stable in the presence of the moderately active D142N mutant of ChiB. The crystal structure of the D142N-HM508 complex revealed that the two sugar moieties bind to the -2 and -1 subsites, whereas the phenyl group interacts with aromatic side chains that line the +1 and +2 subsites. Enzymatic degradation of HM508, as well as a Trp-->Ala mutation in the +2 subsite of ChiB, led to reduced affinity for the inhibitor, showing that interactions between the phenyl group and the enzyme contribute to binding. Interestingly, a complex of enzymatically degraded HM508 with the wild type enzyme showed a chitobiono-delta- lactone bound in the -2 and -1 subsites, despite the fact that the equilibrium between the lactone and the hydroxy acid forms in solution lies far toward the latter. This shows that the active site preferentially binds the E-4 conformation of the -1 sugar, which resembles the proposed transition state of the reaction Y1 - 2004 SN - 0021-9258 ER - TY - JOUR A1 - Vaaje-Kolstad, G. A1 - Houston, Douglas R. A1 - Rao, F. V. A1 - Peter, Martin G. A1 - Synstad, Bjoenar A1 - van Aalten, Daan M. F. A1 - Eijsink, Vincent G. H. T1 - Structure of the D142N mutant of the family 18 chitinase ChiB from Serratia marcescens and its complex with allosamidin N2 - Catalysis by ChiB, a family 18 chitinase from Serratia marcescens, involves a conformational change of Asp142 which is part of a characteristic D140XD142XE144 sequence motif In the free enzyme Asp142 points towards Asp140, whereas it rotates towards the catalytic acid, Glu144, upon ligand binding. Mutation of Asp142 to Asn reduced k(cat) and affinity for allosamidin, a competitive inhibitor. The X-ray structure of the D142N mutant showed that Asn142 points towards Glu144 in the absence of a ligand. The active site also showed other structural adjustments (Tyr10, Ser93) that had previously been observed in the wild-type enzyme upon substrate binding. The X-ray structure of a complex of D142N with allosamidin, a pseudotrisaccharide competitive inhibitor, was essentially identical to that of the wild-type enzyme in complex with the same compound. Thus, the reduced allosamidin affinity in the mutant is not caused by structural changes but solely by the loss of electrostatic interactions with Asp142. The importance of electrostatics was further confirmed by the pH dependence of catalysis and allosamidin inhibition. The pH-dependent apparent affinities for allosamidin were not correlated with k(cat), indicating that it is probably better to view the inhibitor as a mimic of the oxazolinium ion reaction intermediate than as a transition state analogue. (C) 2003 Elsevier B.V. All rights reserved Y1 - 2004 SN - 1570-9639 ER - TY - JOUR A1 - Ziemann, Martin Andreas A1 - Schmidt, Christian A1 - Mirwald, Peter W. T1 - Raman spectroscopic study of the liquid-liquid transition in water Y1 - 2004 SN - 0024-4937 ER - TY - JOUR A1 - Eijsink, Vincent G. H. A1 - Synstad, Bjoenar A1 - Gaseidnes, Sigrid A1 - Komander, David A1 - Houston, Douglas R. A1 - Peter, Martin G. A1 - van Aalten, Daan M. F. T1 - Structure and function of chitinolytic enzymes N2 - The recent work on a variety of family 18 chitonolytic enzymes has yielded important data concerning the structure, substrate-binding, catalysis, inhibitor-binding and even dynamics. These data have been useful in helping to better understand the roles of various types of chitinases in chitin hydrolysis, to rationally engineer the properties of these enzymes, thus making them more suitable as biocatalysts, and to study and understand the effectiveness of natural and designed chitinase inhibitors, which may be of medical interest. On the other hand, the recent work on ChiB shows that catalysis in family 18 chitinases is a highly complicated process, involving larger parts of the enzyme and dynamics. Thus, despite recent discoveries, there is still a lot more to discover about how these enzyme work. Y1 - 2003 SN - 82-471-5901-5 ER - TY - JOUR A1 - Klein, Florian A1 - Feldhahn, Niklas A1 - Lee, Sanggyu A1 - Wang, Hui A1 - Ciuffi, Fiammetta A1 - von Elstermann, Mirko A1 - Toribio, Maria L. A1 - Sauer, Heinrich A1 - Wartenberg, Maria A1 - Barath, Varun Singh A1 - Krönke, Martin A1 - Wernet, Peter A1 - Rowley, Janet D. A1 - Müschen, Markus T1 - T lymphoid differentiation in human bone marrow Y1 - 2003 ER - TY - JOUR A1 - Kamlage, Stefan A1 - Sefkow, Michael A1 - Zimmermann, Nicole A1 - Peter, Martin G. T1 - Concise synthesis of (+)-beta-benzyl gamma-butyrolactones from butynediol Y1 - 2002 ER - TY - JOUR A1 - Peter, Martin G. T1 - Chitin and Chitosan from Animal Sources N2 - A review on the chem. and biochem. of chitin and the chem. and application of chitosan. The following topics were discussed: structure of chitin and chitosan; occurrence and physiol. functions of chitin; detection of chitin in animals and anal. of chitin and chitosan; biosynthesis and biodegrdn. of chitin in animals; prodn. of chitin and chitosan; properties of chitin and chitosan; and applications of chitin and chitosan. Y1 - 2002 SN - 3-527-30227-1 ER - TY - JOUR A1 - Peter, Martin G. T1 - Chitin and Chitosan from Fungi Y1 - 2002 SN - 3-527-30227-1 ER - TY - GEN A1 - Ferenz, Hans-Jürgen A1 - Peter, Martin G. A1 - Berg, Dieter T1 - Inhibition of farnesoic acid methyltransferase by sinefungin N2 - Sinefungin inhibited the S-adenosylmethionine-dependent farnesoic acid methyltransferase in a cell-free system containing a homogenate of corpora allata from female locusts, Locusta migratoria. The enzyme catalyzed the penultimate step of juvenile hormone biosynthesis in the insects. Culturing corpora allata in the presence of sinefungin greatly suppressed juvenile hormone production. The following in vivo effects were visible after injection of the inhibitor: increase in mortality and reduction of total haemolymph protein liter and ovary fresh weight, as well as length of terminal oocytes. Attempts to reverse these effects by topical application of the juvenile hormone analog ZR-515 (methoprene) were only partly successful. Therefore, the in vivo effects may be due to a general inhibition of methyltransferase enzymes in the insect. Sinefungin appeared to be of potential interest as the first representative of a new class of insect growth regulators. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 077 KW - Juvenile hormone analogue KW - Orthoptera KW - Juvenile hormone KW - Biosynthesis KW - Enzyme KW - Corpora allata KW - In vitro KW - Biological activity KW - Enzyme inhibitor Y1 - 1983 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-17016 ER - TY - GEN A1 - Kort, C. A. D. de A1 - Peter, Martin G. A1 - Koopmanschap, A. B. T1 - Binding and degradation of juvenile hormone III by haemolymph proteins of the Colorado potato beetle: a re-examination N2 - The haemolymph of the adult Colorado potato beetle, Lepinotarsa decemlineata Say, contains a high molecular weight (MW > 200,000) JH-III specific binding protein. The Kd value of the protein for racemic JH-III is 1.3 ± 0.2 × 10−7 M. It has a lower affinity for racemic JH-I and it does not bind JH-III-diol or JH-III-acid. The binding protein does discriminate between the enantiomers of synthetic, racemic JH-III as was determined by stereochemical anaysis of the bound and the free JH-III. Incubation of racemic JH-III with crude haemolymph results in preferential formation of (10S)-JH-III-acid, the unnatural configuration. The JH-esterase present in L. decemlineata haemolymph is not enantioselective. It is concluded that the most important function of the binding protein is that of a specific carrier, protecting the natural hormone against degradation by esterases. The carrier does not protect JH-I as efficiently as the lower homologue. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 068 KW - Juvenile hormone KW - Leptinotarsa decemlineata KW - JH-III-specific carrier protein KW - enantioselectivity Y1 - 1983 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16777 ER - TY - GEN A1 - Peter, Martin G. A1 - Förster, Hans T1 - On the structure of Eumelanins : identification of constitutional patterns by solid-state NMR spectroscopy N2 - Aus dem Inhalt: Melanins are complex polyphenolic polymers. They are usually formed in nature by enzyme-catalyzed oxidative polymerization of o-diphenols. The deep black eumelanins, derived from Dopa 1 or dopamine 3, are distinguished from the yellow to brown phaeomelanins obtained from Dopa in the presence of cysteine. Characteristic of eumelanins are the indole units, which are formed from catecholamines by intramolecular addition of the amino groups to the oxidatively generated o-quinones. [...] T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 053 Y1 - 1989 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-17027 ER - TY - GEN A1 - Oliveira Jr, E. N. A1 - Gueddari, Nour E. El A1 - Moerschbacher, Bruno M. A1 - Peter, Martin A1 - Franco, Telma T1 - Growth of phytopathogenic fungi in the presence of partially acetylated chitooligosaccharides N2 - Four phytopathogenic fungi were cultivated up to six days in media containing chitooligosaccharide mixtures differing in average DP and FA. The three different mixtures were named Q3 (which contained oligosaccharides ofDP2–DP10, withDP2–DP7 asmain components), Q2 (which contained oligosaccharides of DP2–DP12, with DP2–DP10 as main components) and Q1 (which derived from Q2 and contained oligomers of DP5–DP8 with hexamer and a heptamer as the main components). The novel aspect of this work is the description of the effect of mixtures of oligosaccharides with different and known composition on fungal growth rates. The growth rate of Alternaria alternata and Rhizopus stolonifer was initially inhibited by Q3 and Q2 at higher concentrations. Q1 had a growth stimulating effect on these two fungi. Growth of Botrytis cinerea was inhibited by Q3 and Q2, while Q1 had no effect on the growth of this fungus. Growth of Penicillium expansum was only slightly inhibited by higher concentrations of sample Q3, while Q2 and Q1 had no effect. The inhibition of growth rates or their resistance toward chitooligosaccharides correlated with the absence or presence of chitinolytic enzymes in the culture media, respectively. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 105 KW - Chitosan KW - Chitinase KW - Fungi KW - Oligosaccharides KW - Phytopathogens Y1 - 2008 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-42646 ER - TY - JOUR A1 - Wanjohi, John M. A1 - Yenesew, Abiy A1 - Midiwo, Jacob O. A1 - Heydenreich, Matthias A1 - Peter, Martin G. A1 - Dreyer, M. A1 - Reichert, M. A1 - Bringmann, Gerhard T1 - Three dimeric anthracene derivatives from the fruits of Bulbine abyssinica N2 - From the fruits of Bulbine abyssinica three new dimeric anthracene derivatives, (P)-8,9,1',8'- tetrahydroxy-3,3'-dimethyl[10,7'-bianthracene]-1,4,9',10'- tetraone (trivial name abyquinone A), (10R)-1,4,8,1',8-pentahydroxy-3,3'-dimethyl-[10,7'-bianthracene]9,9',10' (10H)-trione (trivial name abyquinone B), and (10R)-3,4'-dihydro-1,4,8,3',8',9'-hexahydroxy-3,3'- dimethyl-[10,7'-biant hracene]9,1'(10H,2'H)-dione (trivial name abyquinone Q were isolated. Despite their structural differences, these three compounds are connected to each other by the apparently biomimetic conversion of abyquinone C (a preanthraquinonylanthrone with two stereogenic centers) into B (an anthraquinonylanthrone with one stereogenic center) and finally into A (an axially chiral bianthraquinone) under mild conditions, involving a highly efficient center-to-axis chirality transfer. In addition, the known anthraquinones islandicin and chrysophanol were identified. The structures were determined on the basis of spectroscopical evidences, chemical transformations, and quantum chemical CD calculations. (C) 2005 Elsevier Ltd. All rights reserved Y1 - 2005 SN - 0040-4020 ER - TY - JOUR A1 - Yenesew, Abiy A1 - Kiplagat, John T. A1 - Derese, Solomon A1 - Midiwo, Jacob O. A1 - Kabaru, Jacques M. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - Two unusual rotenoid derivatives, 7a-O-methyl-12a-hydroxydeguelol and spiro-13-homo-13-oxaelliptone, from the seeds of Derris trifoliata N2 - The crude methanol extract of the seeds of Derris trifoliata showed potent and dose dependent larvicidal activity against the 2nd instar larvae of Aedes aegypti. From this extract two unusual rotenoid derivatives, a rotenoloid (named 7a-O-methyl-12a-hydroxydeguelol) and a spirohomooxarotenoid (named spiro-13-homo-13-oxaelliptone), were isolated and characterised. In addition a rare natural chromanone (6,7-dimethoxy-4-chromanone) and the known rotenoids rotenone, tephrosin and dehydrodeguelin were identified. The structures were assigned on the basis of spectroscopic evidence. The larvicidal activity of the crude extract is mainly due to rotenone. (c) 2006 Elsevier Ltd. All rights reserved Y1 - 2006 UR - http://www.sciencedirect.com/science/article/pii/S0031942206000045 U6 - https://doi.org/10.1016/j.phytochem.2006.01.002 ER - TY - JOUR A1 - Yenesew, Abiy A1 - Midiwo, Jacob O. A1 - Guchu, S. M. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - Three iosoflav-3-enes and a 2-arylbenzofuran from the root bark of Erythrina burttii N2 - From the root bark of Erythrina burttii three new isoflav-3-enes, 7,4'-dihydroxy-2'-methoxy-6- (1'',1''-dimethylallyl)isoflav-3-ene (trivial name, burttinol-A), 4'-hydroxy-2'- methoxy-(2'',2''-dimethylpyrano[5'',6'':8,7]isoflav-3-ene (trivial name, burttinol-B), 7,4'-dihydroxy-2'-methoxy-8-(3'',3''-dimethylallyl)isoflav-3-ene (trivial name, burttinol-C), and a new 2-arylbenzofuran, 6,4'-dihydroxy-2'-methoxy-5- (1'',1''-dimethylallyl)-2-arylbenzofuran (trivial name, burttinol-D) were isolated. In addition, the known compounds, abyssinone V-4'-methyl ether, bidwillol A, calopocarpin, erybraedin A, erythrabyssin II, isobavachalcone, phaseollidin and phaseollin were identified. The structures were determined on the basis of spectroscopic evidence. Y1 - 2002 ER - TY - JOUR A1 - Yenesew, Abiy A1 - Mushibe, E. K. A1 - Induli, M. A1 - Derese, Solomon A1 - Midiwo, Jacob O. A1 - Kabaru, Jacques M. A1 - Heydenreich, Matthias A1 - Koch, Andreas A1 - Peter, Martin G. T1 - 7a-O-methyldeguelol, a modified rotenoid with an open ring-C, from the roots of Derris trifoloata N2 - From the acetone extract of the roots of Derris trifoliata an isollavonoid derivative, named 7a-O- methyldeguelol, a modified rotenoid with an open ring-C, representing a new sub-class of isollavonoids (the sub-class is here named as rotenoloid), was isolated and characterised. In addition, the known rotenoids, rotenone, deguelin and alpha-toxicarol, were identified. The structures were determined on the basis of spectroscopic evidence. Rotenone and deguelin were identified as the larvicidal principles of the acetone extract of the roots of Derris trifoliata. (c) 2005 Elsevier Ltd. All rights reserved Y1 - 2005 SN - 0031-9422 ER - TY - JOUR A1 - Yenesew, Abiy A1 - Irungu, Beatrice A1 - Derese, Solomon A1 - Midiwo, Jacob O. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - Two prenylated flavonoids from the stem bark of Erythrina burttii N2 - From the stem bark of Erythrina burttii, a new isoflavone, 5,2',4'-trihydroxy-7-methoxy-6-(3- methylbut-2-enyl)isoflavone (trivial name, 7-O-methylluteone) and a new flavanone, 5,7-dihydroxy-4'-methoxy- 3'-(3-methylbutadienyl)-5'-(3-methylbut-2-enyl)flavanone (trivial name, burttinonedehydrate) along with three known isoflavonoids (8-prenylluteone, 3-O-methylcalopocarpin and genistein) were isolated. The structures were detd. on the basis of spectroscopic evidence. Y1 - 2003 ER - TY - JOUR A1 - Yenesew, Abiy A1 - Derese, Solomon A1 - Midiwo, Jacob O. A1 - Bii, Christine C. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - Antimicrobial flavonoids from the stem bark of Erythrina burttii N2 - The chloroform extract of the stem bark of Erythrina burttii showed antifungal and antibacterial activities using the disk diffusion method. Flavonoids were identified as the active principles. Activities were observed against fungi and Gram(+) bacteria, but the Gram(-) bacteria Escherichia coli was resistant. (c) 2005 Elsevier B.V. All rights reserved Y1 - 2005 SN - 0367-326X ER - TY - THES A1 - Derese, Solomon A1 - Yenesew, Abiy A1 - Midiwo, Jacob O. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - A new isoflavone from stem bark of Millettia dura Y1 - 2003 SN - 1011-3924 ER - TY - JOUR A1 - Yenesew, Abiy A1 - Midiwo, Jacob O. A1 - Meisner, M. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - Two prenylated flavanones from stem bark of erythrina burttii Y1 - 1998 ER - TY - JOUR A1 - Yenesew, Abiy A1 - Midiwo, Jacob O. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - Four isoflavanones from stem bark of erythrina sacleuxii Y1 - 1998 ER - TY - GEN A1 - Bringmann, Gerhard A1 - Mutanyatta-Comar, Joan A1 - Maksimenka, Katja A1 - Wanjohi, John M. A1 - Heydenreich, Matthias A1 - Brun, Reto A1 - Müller, Werner E. G. A1 - Peter, Martin A1 - Midiwo, Jacob O. A1 - Yenesew, Abiy T1 - Joziknipholones A and B : the First Dimeric Phenylanthraquinones, from the Roots of Bulbine frutescens N2 - From the roots of the African plant Bulbine frutescens (Asphodelaceae), two unprecedented novel dimeric phenylanthraquinones, named joziknipholones A and B, possessing axial and centrochirality, were isolated, together with six known compounds. Structural elucidation of the new metabolites was achieved by spectroscopic and chiroptical methods, by reductive cleavage of the central bond between the monomeric phenylanthraquinone and -anthrone portions with sodium dithionite, and by quantum chemical CD calculations. Based on the recently revised absolute axial configuration of the parent phenylanthraquinones, knipholone and knipholone anthrone, the new dimers were attributed to possess the P-configuration (i.e., with the acetyl portions below the anthraquinone plane) at both axes in the case of joziknipholone A, whereas in joziknipholone B, the knipholone part was found to be M-configured. Joziknipholones A and B are active against the chloroquine resistant strain K1 of the malaria pathogen, Plasmodium falciparum, and show moderate activity against murine leukemic lymphoma L5178y cells. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 104 KW - antimalarial activity KW - chirality KW - joziknipholones KW - natural products KW - structure elucidation Y1 - 2008 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-42638 ER - TY - JOUR A1 - von Loeffelholz, Christian A1 - Lieske, Stefanie A1 - Neuschaefer-Rube, Frank A1 - Willmes, Diana M. A1 - Raschzok, Nathanael A1 - Sauer, Igor M. A1 - König, Jörg A1 - Fromm, Martin F. A1 - Horn, Paul A1 - Chatzigeorgiou, Antonios A1 - Pathe-Neuschaefer-Rube, Andrea A1 - Jordan, Jens A1 - Pfeiffer, Andreas F. H. A1 - Mingrone, Geltrude A1 - Bornstein, Stefan R. A1 - Stroehle, Peter A1 - Harms, Christoph A1 - Wunderlich, F. Thomas A1 - Helfand, Stephen L. A1 - Bernier, Michel A1 - de Cabo, Rafael A1 - Shulman, Gerald I. A1 - Chavakis, Triantafyllos A1 - Püschel, Gerhard Paul A1 - Birkenfeld, Andreas L. T1 - The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism BT - official journal of the American Association for the Study of Liver Diseases JF - Hepatology N2 - Reduced expression of the Indy ("I am Not Dead, Yet") gene in lower organisms promotes longevity in a manner akin to caloric restriction. Deletion of the mammalian homolog of Indy (mIndy, Slc13a5) encoding for a plasma membrane-associated citrate transporter expressed highly in the liver, protects mice from high-fat diet-induced and aging-induced obesity and hepatic fat accumulation through a mechanism resembling caloric restriction. We studied a possible role of mIndy in human hepatic fat metabolism. In obese, insulin-resistant patients with nonalcoholic fatty liver disease, hepatic mIndy expression was increased and mIndy expression was also independently associated with hepatic steatosis. In nonhuman primates, a 2-year high-fat, high-sucrose diet increased hepatic mIndy expression. Liver microarray analysis showed that high mIndy expression was associated with pathways involved in hepatic lipid metabolism and immunological processes. Interleukin-6 (IL-6) was identified as a regulator of mIndy by binding to its cognate receptor. Studies in human primary hepatocytes confirmed that IL-6 markedly induced mIndy transcription through the IL-6 receptor and activation of the transcription factor signal transducer and activator of transcription 3, and a putative start site of the human mIndy promoter was determined. Activation of the IL-6-signal transducer and activator of transcription 3 pathway stimulated mIndy expression, enhanced cytoplasmic citrate influx, and augmented hepatic lipogenesis in vivo. In contrast, deletion of mIndy completely prevented the stimulating effect of IL-6 on citrate uptake and reduced hepatic lipogenesis. These data show that mIndy is increased in liver of obese humans and nonhuman primates with NALFD. Moreover, our data identify mIndy as a target gene of IL-6 and determine novel functions of IL-6 through mINDY. Conclusion: Targeting human mINDY may have therapeutic potential in obese patients with nonalcoholic fatty liver disease. German Clinical Trials Register: DRKS00005450. Y1 - 2017 U6 - https://doi.org/10.1002/hep.29089 SN - 0270-9139 SN - 1527-3350 VL - 66 IS - 2 SP - 616 EP - 630 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Koltai, Peter A1 - Lie, Han Cheng A1 - Plonka, Martin T1 - Frechet differentiable drift dependence of Perron-Frobenius and Koopman operators for non-deterministic dynamics JF - Nonlinearity N2 - We prove the Fréchet differentiability with respect to the drift of Perron–Frobenius and Koopman operators associated to time-inhomogeneous ordinary stochastic differential equations. This result relies on a similar differentiability result for pathwise expectations of path functionals of the solution of the stochastic differential equation, which we establish using Girsanov's formula. We demonstrate the significance of our result in the context of dynamical systems and operator theory, by proving continuously differentiable drift dependence of the simple eigen- and singular values and the corresponding eigen- and singular functions of the stochastic Perron–Frobenius and Koopman operators. KW - stochastic differential equations KW - transfer operator KW - Koopman operator KW - Perron-Frobenius operator KW - smooth drift dependence KW - linear response KW - pathwise expectations Y1 - 2019 U6 - https://doi.org/10.1088/1361-6544/ab1f2a SN - 0951-7715 SN - 1361-6544 VL - 32 IS - 11 SP - 4232 EP - 4257 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Kong, Xiang-Zhao A1 - Deuber, Claudia A. A1 - Kittilä, Anniina A1 - Somogyvári, Márk A1 - Mikutis, Gediminas A1 - Bayer, Peter A1 - Stark, Wendelin J. A1 - Saar, Martin O. T1 - Tomographic Reservoir Imaging with DNA-Labeled Silica Nanotracers: The First Field Validation JF - Environmental science & technology N2 - This study presents the first field validation of using DNA-labeled silica nanoparticles as tracers to image subsurface reservoirs by travel time based tomography. During a field campaign in Switzerland, we performed short-pulse tracer tests under a forced hydraulic head gradient to conduct a multisource-multireceiver tracer test and tomographic inversion, determining the two-dimensional hydraulic conductivity field between two vertical wells. Together with three traditional solute dye tracers, we injected spherical silica nanotracers, encoded with synthetic DNA molecules, which are protected by a silica layer against damage due to chemicals, microorganisms, and enzymes. Temporal moment analyses of the recorded tracer concentration breakthrough curves (BTCs) indicate higher mass recovery, less mean residence time, and smaller dispersion of the DNA-labeled nanotracers, compared to solute dye tracers. Importantly, travel time based tomography, using nanotracer BTCs, yields a satisfactory hydraulic conductivity tomogram, validated by the dye tracer results and previous field investigations. These advantages of DNA-labeled nanotracers, in comparison to traditional solute dye tracers, make them well-suited for tomographic reservoir characterizations in fields such as hydrogeology, petroleum engineering, and geothermal energy, particularly with respect to resolving preferential flow paths or the heterogeneity of contact surfaces or by enabling source zone characterizations of dense nonaqueous phase liquids. Y1 - 2018 U6 - https://doi.org/10.1021/acs.est.8b04367 SN - 0013-936X SN - 1520-5851 VL - 52 IS - 23 SP - 13681 EP - 13689 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Buratti, Bonnie J. A1 - Thomas, P. C. A1 - Roussos, E. A1 - Howett, Carly A1 - Seiss, Martin A1 - Hendrix, A. R. A1 - Helfenstein, Paul A1 - Brown, R. H. A1 - Clark, R. N. A1 - Denk, Tilmann A1 - Filacchione, Gianrico A1 - Hoffmann, Holger A1 - Jones, Geraint H. A1 - Khawaja, N. A1 - Kollmann, Peter A1 - Krupp, Norbert A1 - Lunine, Jonathan A1 - Momary, T. W. A1 - Paranicas, Christopher A1 - Postberg, Frank A1 - Sachse, Manuel A1 - Spahn, Frank A1 - Spencer, John A1 - Srama, Ralf A1 - Albin, T. A1 - Baines, K. H. A1 - Ciarniello, Mauro A1 - Economou, Thanasis A1 - Hsu, Hsiang-Wen A1 - Kempf, Sascha A1 - Krimigis, Stamatios M. A1 - Mitchell, Donald A1 - Moragas-Klostermeyer, Georg A1 - Nicholson, Philip D. A1 - Porco, C. C. A1 - Rosenberg, Heike A1 - Simolka, Jonas A1 - Soderblom, Laurence A. T1 - Close Cassini flybys of Saturn’s ring moons Pan, Daphnis, Atlas, Pandora, and Epimetheus JF - Science N2 - Saturn’s main ring system is associated with a set of small moons that either are embedded within it or interact with the rings to alter their shape and composition. Five close flybys of the moons Pan, Daphnis, Atlas, Pandora, and Epimetheus were performed between December 2016 and April 2017 during the ring-grazing orbits of the Cassini mission. Data on the moons’ morphology, structure, particle environment, and composition were returned, along with images in the ultraviolet and thermal infrared. We find that the optical properties of the moons’ surfaces are determined by two competing processes: contamination by a red material formed in Saturn’s main ring system and accretion of bright icy particles or water vapor from volcanic plumes originating on the moon Enceladus. Y1 - 2019 U6 - https://doi.org/10.1126/science.aat2349 SN - 0036-8075 SN - 1095-9203 VL - 364 IS - 6445 SP - 1053 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Schall, Peter A1 - Gossner, Martin M. A1 - Heinrichs, Steffi A1 - Fischer, Markus A1 - Boch, Steffen A1 - Prati, Daniel A1 - Jung, Kirsten A1 - Baumgartner, Vanessa A1 - Blaser, Stefan A1 - Böhm, Stefan A1 - Buscot, Francois A1 - Daniel, Rolf A1 - Goldmann, Kezia A1 - Kaiser, Kristin A1 - Kahl, Tiemo A1 - Lange, Markus A1 - Müller, Jörg Hans A1 - Overmann, Jörg A1 - Renner, Swen C. A1 - Schulze, Ernst-Detlef A1 - Sikorski, Johannes A1 - Tschapka, Marco A1 - Türke, Manfred A1 - Weisser, Wolfgang W. A1 - Wemheuer, Bernd A1 - Wubet, Tesfaye A1 - Ammer, Christian T1 - The impact of even-aged and uneven-aged forest management on regional biodiversity of multiple taxa in European beech forests JF - Journal of applied ecology : an official journal of the British Ecological Society N2 - 1. For managed temperate forests, conservationists and policymakers favour fine-grained uneven-aged (UEA) management over more traditional coarse-grained even-aged (EA) management, based on the assumption that within-stand habitat heterogeneity enhances biodiversity. There is, however, little empirical evidence to support this assumption. We investigated for the first time how differently grained forest management systems affect the biodiversity of multiple above- and below-ground taxa across spatial scales. 2. We sampled 15 taxa of animals, plants, fungi and bacteria within the largest contiguous beech forest landscape of Germany and classified them into functional groups. Selected forest stands have been managed for more than a century at different spatial grains. The EA (coarse-grained management) and UEA (fine-grained) forests are comparable in spatial arrangement, climate and soil conditions. These were compared to forests of a nearby national park that have been unmanaged for at least 20years. We used diversity accumulation curves to compare -diversity for Hill numbers D-0 (species richness), D-1 (Shannon diversity) and D-2 (Simpson diversity) between the management systems. Beta diversity was quantified as multiple-site dissimilarity. 3. Gamma diversity was higher in EA than in UEA forests for at least one of the three Hill numbers for six taxa (up to 77%), while eight showed no difference. Only bacteria showed the opposite pattern. Higher -diversity in EA forests was also found for forest specialists and saproxylic beetles. 4. Between-stand -diversity was higher in EA than in UEA forests for one-third (all species) and half (forest specialists) of all taxa, driven by environmental heterogeneity between age-classes, while -diversity showed no directional response across taxa or for forest specialists. 5. Synthesis and applications. Comparing EA and uneven-aged forest management in Central European beech forests, our results show that a mosaic of different age-classes is more important for regional biodiversity than high within-stand heterogeneity. We suggest reconsidering the current trend of replacing even-aged management in temperate forests. Instead, the variability of stages and stand structures should be increased to promote landscape-scale biodiversity. KW - beta diversity KW - forest specialists KW - gamma diversity KW - heterogeneity KW - Hill numbers KW - saproxylic beetles KW - spatial grain KW - species accumulation curve KW - species richness KW - species turnover Y1 - 2017 U6 - https://doi.org/10.1111/1365-2664.12950 SN - 0021-8901 SN - 1365-2664 VL - 55 IS - 1 SP - 267 EP - 278 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Kolora, Sree Rohit Raj A1 - Weigert, Anne A1 - Saffari, Amin A1 - Kehr, Stephanie A1 - Walter Costa, Maria Beatriz A1 - Spröer, Cathrin A1 - Indrischek, Henrike A1 - Chintalapati, Manjusha A1 - Lohse, Konrad A1 - Doose, Gero A1 - Overmann, Jörg A1 - Bunk, Boyke A1 - Bleidorn, Christoph A1 - Grimm-Seyfarth, Annegret A1 - Henle, Klaus A1 - Nowick, Katja A1 - Faria, Rui A1 - Stadler, Peter F. A1 - Schlegel, Martin T1 - Divergent evolution in the genomes of closely related lacertids, Lacerta viridis and L. bilineata, and implications for speciation JF - GigaScience N2 - Background Lacerta viridis and Lacerta bilineata are sister species of European green lizards (eastern and western clades, respectively) that, until recently, were grouped together as the L. viridis complex. Genetic incompatibilities were observed between lacertid populations through crossing experiments, which led to the delineation of two separate species within the L. viridis complex. The population history of these sister species and processes driving divergence are unknown. We constructed the first high-quality de novo genome assemblies for both L. viridis and L. bilineata through Illumina and PacBio sequencing, with annotation support provided from transcriptome sequencing of several tissues. To estimate gene flow between the two species and identify factors involved in reproductive isolation, we studied their evolutionary history, identified genomic rearrangements, detected signatures of selection on non-coding RNA, and on protein-coding genes. Findings Here we show that gene flow was primarily unidirectional from L. bilineata to L. viridis after their split at least 1.15 million years ago. We detected positive selection of the non-coding repertoire; mutations in transcription factors; accumulation of divergence through inversions; selection on genes involved in neural development, reproduction, and behavior, as well as in ultraviolet-response, possibly driven by sexual selection, whose contribution to reproductive isolation between these lacertid species needs to be further evaluated. Conclusion The combination of short and long sequence reads resulted in one of the most complete lizard genome assemblies. The characterization of a diverse array of genomic features provided valuable insights into the demographic history of divergence among European green lizards, as well as key species differences, some of which are candidates that could have played a role in speciation. In addition, our study generated valuable genomic resources that can be used to address conservation-related issues in lacertids. KW - sister species KW - PacBio and Illumina KW - de novo hybrid assembly KW - transcripts KW - noncoding RNA KW - zinc fingers KW - positive selection KW - UV response KW - inversions KW - gene flow Y1 - 2018 U6 - https://doi.org/10.1093/gigascience/giy160 SN - 2047-217X VL - 8 IS - 2 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Heinrichs, Steffi A1 - Ammer, Christian A1 - Mund, Martina A1 - Boch, Steffen A1 - Budde, Sabine A1 - Fischer, Markus A1 - Mueller, Joerg A1 - Schoening, Ingo A1 - Schulze, Ernst-Detlef A1 - Schmidt, Wolfgang A1 - Weckesser, Martin A1 - Schall, Peter T1 - Landscape-Scale Mixtures of Tree Species are More Effective than Stand-Scale Mixtures for Biodiversity of Vascular Plants, Bryophytes and Lichens JF - Forests N2 - Tree species diversity can positively affect the multifunctionality of forests. This is why conifer monocultures of Scots pine and Norway spruce, widely promoted in Central Europe since the 18th and 19th century, are currently converted into mixed stands with naturally dominant European beech. Biodiversity is expected to benefit from these mixtures compared to pure conifer stands due to increased abiotic and biotic resource heterogeneity. Evidence for this assumption is, however, largely lacking. Here, we investigated the diversity of vascular plants, bryophytes and lichens at the plot (alpha diversity) and at the landscape (gamma diversity) level in pure and mixed stands of European beech and conifer species (Scots pine, Norway spruce, Douglas fir) in four regions in Germany. We aimed to identify compositions of pure and mixed stands in a hypothetical forest landscape that can optimize gamma diversity of vascular plants, bryophytes and lichens within regions. Results show that gamma diversity of the investigated groups is highest when a landscape comprises different pure stands rather than tree species mixtures at the stand scale. Species mainly associated with conifers rely on light regimes that are only provided in pure conifer forests, whereas mixtures of beech and conifers are more similar to beech stands. Combining pure beech and pure conifer stands at the landscape scale can increase landscape level biodiversity and conserve species assemblages of both stand types, while landscapes solely composed of stand scale tree species mixtures could lead to a biodiversity reduction of a combination of investigated groups of 7 up to 20%. KW - Fagus sylvatica KW - Pinus sylvestris KW - Picea abies KW - Pseudotsuga menziesii KW - forest management KW - tree species diversity KW - forest conversion KW - gamma diversity KW - landscape scale KW - Biodiversity Exploratories Y1 - 2019 U6 - https://doi.org/10.3390/f10010073 SN - 1999-4907 VL - 10 IS - 1 PB - MDPI CY - Basel ER - TY - JOUR A1 - Zabl, Johannes A1 - Bouche, Nicolas F. A1 - Schroetter, Ilane A1 - Wendt, Martin A1 - Finley, Hayley A1 - Schaye, Joop A1 - Conseil, Simon A1 - Contini, Thierry A1 - Marino, Raffaella Anna A1 - Mitchell, Peter A1 - Muzahid, Sowgat A1 - Pezzulli, Gabriele A1 - Wisotzki, Lutz T1 - MusE GAs FLOw and Wind (MEGAFLOW) BT - II. A study of gas accretion around z approximate to 1 star-forming galaxies with background quasars JF - Monthly notices of the Royal Astronomical Society N2 - We use the MusE GAs FLOw and Wind (MEGAFLOW) survey to study the kinematics of extended disc-like structures of cold gas around z approximate to 1 star-forming galaxies. The combination of VLT/MUSE and VLT/UVES observations allows us to connect the kinematics of the gas measured through MgII quasar absorption spectroscopy to the kinematics and orientation of the associated galaxies constrained through integral field spectroscopy. Confirming previous results, we find that the galaxy-absorber pairs of the MEGAFLOW survey follow a strong bimodal distribution, consistent with a picture of MgII absorption being predominantly present in outflow cones and extended disc-like structures. This allows us to select a bona-fide sample of galaxy-absorber pairs probing these discs for impact paramometers of 10-70 kpc. We test the hypothesis that the disc-like gas is co-rotating with the galaxy discs, and find that for seven out of nine pairs the absorption velocity shares the sign of the disc velocity, disfavouring random orbits. We further show that the data are roughly consistent with inflow velocities and angular momenta predicted by simulations, and that the corresponding mass accretion rates are sufficient to balance the star formation rates. KW - galaxies: evolution KW - galaxies: formation KW - galaxies: haloes KW - galaxies: kinematics and dynamics KW - quasars: absorption lines Y1 - 2019 U6 - https://doi.org/10.1093/mnras/stz392 SN - 0035-8711 SN - 1365-2966 VL - 485 IS - 2 SP - 1961 EP - 1980 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Schmidt, Katja A1 - Martin-Lopez, Berta A1 - Phillips, Peter M. A1 - Julius, Eike A1 - Makan, Neville A1 - Walz, Ariane T1 - Key landscape features in the provision of ecosystem services BT - Insights for management JF - Land use policy N2 - Whereas ecosystem service research is increasingly being promoted in science and policy, the utilisation of ecosystem services knowledge remains largely underexplored for regional ecosystem management. To overcome the mere generation of knowledge and contribute to decision-making, scientists are facing the challenge of articulating specific implications of the ecosystem service approach for practical land use management. In this contribution, we compare the results of participatory mapping of ecosystem services with the existing management plan for the Pentland Hills Regional Park (Scotland, UK) to inform its future management plan. By conducting participatory mapping in a workshop with key stakeholders (n = 20), we identify hotspots of ecosystem services and the landscape features underpinning such hotspots. We then analyse to what extent these landscape features are the focus of the current management plan. We found a clear mismatch between the key landscape features underpinning the provision of ecosystem services and the management strategy suggested. Our findings allow for a better understanding of the required focus of future land use management to account for ecosystem services. KW - Participatory mapping KW - PPGIS KW - Landscape features KW - Content analysis KW - Land use management KW - Operationalisation Y1 - 2018 U6 - https://doi.org/10.1016/j.landusepol.2018.12.022 SN - 0264-8377 SN - 1873-5754 VL - 82 SP - 353 EP - 366 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Wilken, Florian A1 - Baur, Martin A1 - Sommer, Michael A1 - Deumlich, Detlef A1 - Bens, Oliver A1 - Fiener, Peter T1 - Uncertainties in rainfall kinetic energy-intensity relations for soil erosion modelling JF - Catena : an interdisciplinary journal of soil science, hydrology, geomorphology focusing on geoecology and landscape evolution N2 - For bare soil conditions, the most important process driving and initiating splash and interrill erosion is the detachment of soil particles via raindrop impact. The kinetic energy of a rainfall event is controlled by the drop size and fall velocity distribution, which is often directly or indirectly implemented in erosion models. Therefore, numerous theoretical functions have been developed for the estimation of rainfall kinetic energy from available rainfall intensity measurements. The aim of this study is to assess differences inherent in a wide number of kinetic energy-rainfall intensity (KE-I) relations and their role in soil erosion modelling. Therefore, 32 KE-I relations are compared against measured rainfall energies based on optical distrometer measurements carried out at five stations of two substantially different rainfall regimes. These allow for continuous high-resolution (1-min) direct measurements of rainfall kinetic energies from a detailed spectrum of measured drop sizes and corresponding fall velocities. To quantify the effect of different KE-I relations on sediment delivery, we apply the erosion model WATEM/SEDEM in an experimental setup to four catchments of NE-Germany. The distrometer data shows substantial differences between measured and theoretical models of drop size and fall velocity distributions. For low intensities the number of small drops is overestimated by the Marshall and Palmer (1948; MP) drop size distribution, while for high intensities the proportion of large drops is overestimated by the MP distribution. The distrometer measurements show a considerable proportion of large drops falling at slower velocities than predicted by the Gunn and Kinzer (1949) terminal velocity model. For almost all rainfall events at all stations, the KE-I relations predicted higher cumulative kinetic energy sums compared to the direct measurements of the optical distrometers. The different KE-I relations show individual characteristics over the course of rainfall intensity levels. Our results indicate a high sensitivity (up to a range from 10 to 27 t ha(-1)) of the simulated sediment delivery related to different KE-I relations. Hence, the uncertainty associated with KE-I relations for soil erosion modelling is of critical importance. KW - Rainfall kinetic energy KW - Drop size distribution KW - Drop fall velocity KW - Soil erosion modelling KW - Optical distrometer Y1 - 2018 U6 - https://doi.org/10.1016/j.catena.2018.07.002 SN - 0341-8162 SN - 1872-6887 VL - 171 SP - 234 EP - 244 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Froyland, Gary A1 - Koltai, Peter A1 - Stahn, Martin T1 - Computation and optimal perturbation of finite-time coherent sets for aperiodic flows without trajectory integration JF - SIAM journal on applied dynamical systems N2 - Understanding the macroscopic behavior of dynamical systems is an important tool to unravel transport mechanisms in complex flows. A decomposition of the state space into coherent sets is a popular way to reveal this essential macroscopic evolution. To compute coherent sets from an aperiodic time-dependent dynamical system we consider the relevant transfer operators and their infinitesimal generators on an augmented space-time manifold. This space-time generator approach avoids trajectory integration and creates a convenient linearization of the aperiodic evolution. This linearization can be further exploited to create a simple and effective spectral optimization methodology for diminishing or enhancing coherence. We obtain explicit solutions for these optimization problems using Lagrange multipliers and illustrate this technique by increasing and decreasing mixing of spatial regions through small velocity field perturbations. KW - coherent set KW - mixing KW - transfer operator KW - infinitesimal generator KW - unsteady flow KW - mixing optimization Y1 - 2020 U6 - https://doi.org/10.1137/19M1261791 SN - 1536-0040 VL - 19 IS - 3 SP - 1659 EP - 1700 PB - Society for Industrial and Applied Mathematics CY - Philadelphia ER - TY - JOUR A1 - Grott, Saskia A1 - Peter, Martin G. A1 - Linker, Torsten A1 - Sefkow, Michael A1 - Kroll, Jürgen A1 - Koetz, Joachim A1 - Laschewsky, André A1 - Lokatis, Siegfried A1 - Rheinberg, Falko A1 - Manig, Yvette T1 - Portal = Chemie: Werkstoffe, Wirkstoffe, Lebensvorgänge BT - Die Potsdamer Universitätszeitung N2 - Aus dem Inhalt: - Chemie: Werkstoffe, Wirkstoffe, Lebensvorgänge - Institut für Kirchenrecht gegründet - Computerlinguisten erstellen digitales Wörterbuch - Vom Spaß am Graffiti-Sprayen T3 - Portal: Das Potsdamer Universitätsmagazin - 01-02/2003 Y1 - 2003 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-439713 SN - 1618-6893 IS - 01-02/2003 ER - TY - JOUR A1 - Bringmann, Gerhard A1 - Mutanyatta-Comar, Joan A1 - Maksimenka, Katja A1 - Wanjohi, John M. A1 - Heydenreich, Matthias A1 - Brun, Reto A1 - Müller, Werner E. G. A1 - Peter, Martin G. A1 - Midiwo, Jacob O. A1 - Yenesew, Abiy T1 - Joziknipholones A and B : the first dimeric phenylanthraquinones, from the roots of Bulbine frutescens N2 - From the roots of the African plant Bulbine frutescens (Asphodelaceae), two unprecedented novel dimeric phenylanthraquinones, named joziknipholones A and B, possessing axial and centrochirality, were isolated, together with six known compounds. Structural elucidation of the new metabolites was achieved by spectroscopic and chiroptical methods, by reductive cleavage of the central bond between the monomeric phenylanthraquinone and -anthrone portions with sodium dithionite, and by quantum chemical CD calculations. Based on the recently revised absolute axial configuration of the parent phenylanthraquinones, knipholone and knipholone anthrone, the new dimers were attributed to possess the P- configuration (i.e., with the acetyl portions below the anthraquinone plane) at both axes in the case of joziknipholone A, whereas in joziknipholone B, the knipholone part was found to be M-configured. Joziknipholones A and B are active against the chloroquine resistant strain K1 of the malaria pathogen, Plasmodium falciparum, and show moderate activity against murine leukemic lymphoma L5178y cells. Y1 - 2008 UR - http://www3.interscience.wiley.com/journal/26293/home?CRETRY=1&SRETRY=0 SN - 0947-6539 ER - TY - GEN A1 - Peter, Martin G. T1 - Chemische Modifikation von Biopolymeren durch Chinone und Chinonmethide N2 - Chinone und Vorstufen, die oxidativ in Chinone und/oder Chinonmethide umgewandelt werden können, sind in der Natur weit verbreitet. Als sekundäre Naturstoffe wirken sie häufig antibiotisch, cytotoxisch, aber auch pathogen, und eine Reihe von Pflanzen und Tieren benutzt chinoide Substanzen als Abwehrstoffe, oft mit spektakulärem Erfolg. Auf makromolekularer Ebene spielen Chinonmethide im Pflanzenreich eine Schlüsselrolle bei der Biosynthese von Lignin, während die Bildung von Melanoproteinen ein Beispiel für Reaktionen von o-Chinonen im Tierreich ist. Bei den Insekten dienen Chinone und Chinonmethide zur Bildung des lebensnotwendigen Exoskeletts. Die Reaktivität von Chinonen in biologischen Systemen hat auch für den Menschen unmittelbare Bedeutung in pharmazeutischer, toxikologischer und technologischer Hinsicht. Den Beispielen in diesem Aufsatz liegt ein gemeinsames Prinzip zugrunde, nämlich die chemische Modifikation von Biopolymeren durch Chinone und Chinonmethide. Wie sich besonders bei einer detaillierteren Betrachtung der Reaktionen zeigt, die zur Sklerotisierung der Insektencuticula führen, sind in den letzten Jahren wichtige neue Erkenntnisse hinzugekommen, die vor allem durch die modernen Methoden der Stofftrennung und der Festkörper-NMR-Spektroskopie ermöglicht worden sind. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 043 Y1 - 1989 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16802 ER - TY - GEN A1 - Peter, Martin G. T1 - Products of in vitro oxidation of N-acetyldopamine as possible components in the sclerotization of insect cuticle N2 - [1-14C]-N-Acetyldopamine (NADA) was oxidized in the presence of methyl [3-3H]-β-alanate with mushroom tyrosinase. The complex mixture of reaction products was partly resolved by chromatographic procedures and analyzed by spectroscopic methods. Methyl-β-alanate is incorporated to only a small extent into oxidation products of NADA which inter alia are presumed to be oligomeric hydroxyquinones. After oxidation of [1-14C, 2-3H]-NADA with preparations from tanning Manduca sexta pupal cuticle, N-acetylnoradrenalin was identified as one of the products. Binding of radioactivity to melanin-like material was also observed. These results suggest that oxidation products different from those formulated usually for the crosslinkages between protein amino groups and N-acetyldopaquinone are deposited in darkly brown coloured insect cuticles during sclerotization. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 041 KW - N-acetyldopamine KW - sclerotization KW - tyrosinase; o-quinones KW - tanning agents Y1 - 1980 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16759 ER -