TY - JOUR A1 - Wuttke, Matthias A1 - Li, Yong A1 - Li, Man A1 - Sieber, Karsten B. A1 - Feitosa, Mary F. A1 - Gorski, Mathias A1 - Tin, Adrienne A1 - Wang, Lihua A1 - Chu, Audrey Y. A1 - Hoppmann, Anselm A1 - Kirsten, Holger A1 - Giri, Ayush A1 - Chai, Jin-Fang A1 - Sveinbjornsson, Gardar A1 - Tayo, Bamidele O. A1 - Nutile, Teresa A1 - Fuchsberger, Christian A1 - Marten, Jonathan A1 - Cocca, Massimiliano A1 - Ghasemi, Sahar A1 - Xu, Yizhe A1 - Horn, Katrin A1 - Noce, Damia A1 - Van der Most, Peter J. A1 - Sedaghat, Sanaz A1 - Yu, Zhi A1 - Akiyama, Masato A1 - Afaq, Saima A1 - Ahluwalia, Tarunveer Singh A1 - Almgren, Peter A1 - Amin, Najaf A1 - Arnlov, Johan A1 - Bakker, Stephan J. L. A1 - Bansal, Nisha A1 - Baptista, Daniela A1 - Bergmann, Sven A1 - Biggs, Mary L. A1 - Biino, Ginevra A1 - Boehnke, Michael A1 - Boerwinkle, Eric A1 - Boissel, Mathilde A1 - Böttinger, Erwin A1 - Boutin, Thibaud S. A1 - Brenner, Hermann A1 - Brumat, Marco A1 - Burkhardt, Ralph A1 - Butterworth, Adam S. A1 - Campana, Eric A1 - Campbell, Archie A1 - Campbell, Harry A1 - Canouil, Mickael A1 - Carroll, Robert J. A1 - Catamo, Eulalia A1 - Chambers, John C. A1 - Chee, Miao-Ling A1 - Chee, Miao-Li A1 - Chen, Xu A1 - Cheng, Ching-Yu A1 - Cheng, Yurong A1 - Christensen, Kaare A1 - Cifkova, Renata A1 - Ciullo, Marina A1 - Concas, Maria Pina A1 - Cook, James P. A1 - Coresh, Josef A1 - Corre, Tanguy A1 - Sala, Cinzia Felicita A1 - Cusi, Daniele A1 - Danesh, John A1 - Daw, E. Warwick A1 - De Borst, Martin H. A1 - De Grandi, Alessandro A1 - De Mutsert, Renee A1 - De Vries, Aiko P. J. A1 - Degenhardt, Frauke A1 - Delgado, Graciela A1 - Demirkan, Ayse A1 - Di Angelantonio, Emanuele A1 - Dittrich, Katalin A1 - Divers, Jasmin A1 - Dorajoo, Rajkumar A1 - Eckardt, Kai-Uwe A1 - Ehret, Georg A1 - Elliott, Paul A1 - Endlich, Karlhans A1 - Evans, Michele K. A1 - Felix, Janine F. A1 - Foo, Valencia Hui Xian A1 - Franco, Oscar H. A1 - Franke, Andre A1 - Freedman, Barry I. A1 - Freitag-Wolf, Sandra A1 - Friedlander, Yechiel A1 - Froguel, Philippe A1 - Gansevoort, Ron T. A1 - Gao, He A1 - Gasparini, Paolo A1 - Gaziano, J. Michael A1 - Giedraitis, Vilmantas A1 - Gieger, Christian A1 - Girotto, Giorgia A1 - Giulianini, Franco A1 - Gogele, Martin A1 - Gordon, Scott D. A1 - Gudbjartsson, Daniel F. A1 - Gudnason, Vilmundur A1 - Haller, Toomas A1 - Hamet, Pavel A1 - Harris, Tamara B. A1 - Hartman, Catharina A. A1 - Hayward, Caroline A1 - Hellwege, Jacklyn N. A1 - Heng, Chew-Kiat A1 - Hicks, Andrew A. A1 - Hofer, Edith A1 - Huang, Wei A1 - Hutri-Kahonen, Nina A1 - Hwang, Shih-Jen A1 - Ikram, M. Arfan A1 - Indridason, Olafur S. A1 - Ingelsson, Erik A1 - Ising, Marcus A1 - Jaddoe, Vincent W. V. A1 - Jakobsdottir, Johanna A1 - Jonas, Jost B. A1 - Joshi, Peter K. A1 - Josyula, Navya Shilpa A1 - Jung, Bettina A1 - Kahonen, Mika A1 - Kamatani, Yoichiro A1 - Kammerer, Candace M. A1 - Kanai, Masahiro A1 - Kastarinen, Mika A1 - Kerr, Shona M. A1 - Khor, Chiea-Chuen A1 - Kiess, Wieland A1 - Kleber, Marcus E. A1 - Koenig, Wolfgang A1 - Kooner, Jaspal S. A1 - Korner, Antje A1 - Kovacs, Peter A1 - Kraja, Aldi T. A1 - Krajcoviechova, Alena A1 - Kramer, Holly A1 - Kramer, Bernhard K. A1 - Kronenberg, Florian A1 - Kubo, Michiaki A1 - Kuhnel, Brigitte A1 - Kuokkanen, Mikko A1 - Kuusisto, Johanna A1 - La Bianca, Martina A1 - Laakso, Markku A1 - Lange, Leslie A. A1 - Langefeld, Carl D. A1 - Lee, Jeannette Jen-Mai A1 - Lehne, Benjamin A1 - Lehtimaki, Terho A1 - Lieb, Wolfgang A1 - Lim, Su-Chi A1 - Lind, Lars A1 - Lindgren, Cecilia M. A1 - Liu, Jun A1 - Liu, Jianjun A1 - Loeffler, Markus A1 - Loos, Ruth J. F. A1 - Lucae, Susanne A1 - Lukas, Mary Ann A1 - Lyytikainen, Leo-Pekka A1 - Magi, Reedik A1 - Magnusson, Patrik K. E. A1 - Mahajan, Anubha A1 - Martin, Nicholas G. A1 - Martins, Jade A1 - Marz, Winfried A1 - Mascalzoni, Deborah A1 - Matsuda, Koichi A1 - Meisinger, Christa A1 - Meitinger, Thomas A1 - Melander, Olle A1 - Metspalu, Andres A1 - Mikaelsdottir, Evgenia K. A1 - Milaneschi, Yuri A1 - Miliku, Kozeta A1 - Mishra, Pashupati P. A1 - Program, V. A. Million Veteran A1 - Mohlke, Karen L. A1 - Mononen, Nina A1 - Montgomery, Grant W. A1 - Mook-Kanamori, Dennis O. A1 - Mychaleckyj, Josyf C. A1 - Nadkarni, Girish N. A1 - Nalls, Mike A. A1 - Nauck, Matthias A1 - Nikus, Kjell A1 - Ning, Boting A1 - Nolte, Ilja M. A1 - Noordam, Raymond A1 - Olafsson, Isleifur A1 - Oldehinkel, Albertine J. A1 - Orho-Melander, Marju A1 - Ouwehand, Willem H. A1 - Padmanabhan, Sandosh A1 - Palmer, Nicholette D. A1 - Palsson, Runolfur A1 - Penninx, Brenda W. J. H. A1 - Perls, Thomas A1 - Perola, Markus A1 - Pirastu, Mario A1 - Pirastu, Nicola A1 - Pistis, Giorgio A1 - Podgornaia, Anna I. A1 - Polasek, Ozren A1 - Ponte, Belen A1 - Porteous, David J. A1 - Poulain, Tanja A1 - Pramstaller, Peter P. A1 - Preuss, Michael H. A1 - Prins, Bram P. A1 - Province, Michael A. A1 - Rabelink, Ton J. A1 - Raffield, Laura M. A1 - Raitakari, Olli T. A1 - Reilly, Dermot F. A1 - Rettig, Rainer A1 - Rheinberger, Myriam A1 - Rice, Kenneth M. A1 - Ridker, Paul M. A1 - Rivadeneira, Fernando A1 - Rizzi, Federica A1 - Roberts, David J. A1 - Robino, Antonietta A1 - Rossing, Peter A1 - Rudan, Igor A1 - Rueedi, Rico A1 - Ruggiero, Daniela A1 - Ryan, Kathleen A. A1 - Saba, Yasaman A1 - Sabanayagam, Charumathi A1 - Salomaa, Veikko A1 - Salvi, Erika A1 - Saum, Kai-Uwe A1 - Schmidt, Helena A1 - Schmidt, Reinhold A1 - Ben Schottker, A1 - Schulz, Christina-Alexandra A1 - Schupf, Nicole A1 - Shaffer, Christian M. A1 - Shi, Yuan A1 - Smith, Albert V. A1 - Smith, Blair H. A1 - Soranzo, Nicole A1 - Spracklen, Cassandra N. A1 - Strauch, Konstantin A1 - Stringham, Heather M. A1 - Stumvoll, Michael A1 - Svensson, Per O. A1 - Szymczak, Silke A1 - Tai, E-Shyong A1 - Tajuddin, Salman M. A1 - Tan, Nicholas Y. Q. A1 - Taylor, Kent D. A1 - Teren, Andrej A1 - Tham, Yih-Chung A1 - Thiery, Joachim A1 - Thio, Chris H. L. A1 - Thomsen, Hauke A1 - Thorleifsson, Gudmar A1 - Toniolo, Daniela A1 - Tonjes, Anke A1 - Tremblay, Johanne A1 - Tzoulaki, Ioanna A1 - Uitterlinden, Andre G. A1 - Vaccargiu, Simona A1 - Van Dam, Rob M. A1 - Van der Harst, Pim A1 - Van Duijn, Cornelia M. A1 - Edward, Digna R. Velez A1 - Verweij, Niek A1 - Vogelezang, Suzanne A1 - Volker, Uwe A1 - Vollenweider, Peter A1 - Waeber, Gerard A1 - Waldenberger, Melanie A1 - Wallentin, Lars A1 - Wang, Ya Xing A1 - Wang, Chaolong A1 - Waterworth, Dawn M. A1 - Bin Wei, Wen A1 - White, Harvey A1 - Whitfield, John B. A1 - Wild, Sarah H. A1 - Wilson, James F. A1 - Wojczynski, Mary K. A1 - Wong, Charlene A1 - Wong, Tien-Yin A1 - Xu, Liang A1 - Yang, Qiong A1 - Yasuda, Masayuki A1 - Yerges-Armstrong, Laura M. A1 - Zhang, Weihua A1 - Zonderman, Alan B. A1 - Rotter, Jerome I. A1 - Bochud, Murielle A1 - Psaty, Bruce M. A1 - Vitart, Veronique A1 - Wilson, James G. A1 - Dehghan, Abbas A1 - Parsa, Afshin A1 - Chasman, Daniel I. A1 - Ho, Kevin A1 - Morris, Andrew P. A1 - Devuyst, Olivier A1 - Akilesh, Shreeram A1 - Pendergrass, Sarah A. A1 - Sim, Xueling A1 - Boger, Carsten A. A1 - Okada, Yukinori A1 - Edwards, Todd L. A1 - Snieder, Harold A1 - Stefansson, Kari A1 - Hung, Adriana M. A1 - Heid, Iris M. A1 - Scholz, Markus A1 - Teumer, Alexander A1 - Kottgen, Anna A1 - Pattaro, Cristian T1 - A catalog of genetic loci associated with kidney function from analyses of a million individuals JF - Nature genetics N2 - Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these,147 were likely to be relevant for kidney function on the basis of associations with the alternative kidney function marker blood urea nitrogen (n = 416,178). Pathway and enrichment analyses, including mouse models with renal phenotypes, support the kidney as the main target organ. A genetic risk score for lower eGFR was associated with clinically diagnosed CKD in 452,264 independent individuals. Colocalization analyses of associations with eGFR among 783,978 European-ancestry individuals and gene expression across 46 human tissues, including tubulo-interstitial and glomerular kidney compartments, identified 17 genes differentially expressed in kidney. Fine-mapping highlighted missense driver variants in 11 genes and kidney-specific regulatory variants. These results provide a comprehensive priority list of molecular targets for translational research. Y1 - 2019 U6 - https://doi.org/10.1038/s41588-019-0407-x SN - 1061-4036 SN - 1546-1718 VL - 51 IS - 6 SP - 957 EP - + PB - Nature Publ. Group CY - New York ER - TY - JOUR A1 - Tucker, Marlee A. A1 - Boehning-Gaese, Katrin A1 - Fagan, William F. A1 - Fryxell, John M. A1 - Van Moorter, Bram A1 - Alberts, Susan C. A1 - Ali, Abdullahi H. A1 - Allen, Andrew M. A1 - Attias, Nina A1 - Avgar, Tal A1 - Bartlam-Brooks, Hattie A1 - Bayarbaatar, Buuveibaatar A1 - Belant, Jerrold L. A1 - Bertassoni, Alessandra A1 - Beyer, Dean A1 - Bidner, Laura A1 - van Beest, Floris M. A1 - Blake, Stephen A1 - Blaum, Niels A1 - Bracis, Chloe A1 - Brown, Danielle A1 - de Bruyn, P. J. Nico A1 - Cagnacci, Francesca A1 - Calabrese, Justin M. A1 - Camilo-Alves, Constanca A1 - Chamaille-Jammes, Simon A1 - Chiaradia, Andre A1 - Davidson, Sarah C. A1 - Dennis, Todd A1 - DeStefano, Stephen A1 - Diefenbach, Duane A1 - Douglas-Hamilton, Iain A1 - Fennessy, Julian A1 - Fichtel, Claudia A1 - Fiedler, Wolfgang A1 - Fischer, Christina A1 - Fischhoff, Ilya A1 - Fleming, Christen H. A1 - Ford, Adam T. A1 - Fritz, Susanne A. A1 - Gehr, Benedikt A1 - Goheen, Jacob R. A1 - Gurarie, Eliezer A1 - Hebblewhite, Mark A1 - Heurich, Marco A1 - Hewison, A. J. Mark A1 - Hof, Christian A1 - Hurme, Edward A1 - Isbell, Lynne A. A1 - Janssen, Rene A1 - Jeltsch, Florian A1 - Kaczensky, Petra A1 - Kane, Adam A1 - Kappeler, Peter M. A1 - Kauffman, Matthew A1 - Kays, Roland A1 - Kimuyu, Duncan A1 - Koch, Flavia A1 - Kranstauber, Bart A1 - LaPoint, Scott A1 - Leimgruber, Peter A1 - Linnell, John D. C. A1 - Lopez-Lopez, Pascual A1 - Markham, A. Catherine A1 - Mattisson, Jenny A1 - Medici, Emilia Patricia A1 - Mellone, Ugo A1 - Merrill, Evelyn A1 - Mourao, Guilherme de Miranda A1 - Morato, Ronaldo G. A1 - Morellet, Nicolas A1 - Morrison, Thomas A. A1 - Diaz-Munoz, Samuel L. A1 - Mysterud, Atle A1 - Nandintsetseg, Dejid A1 - Nathan, Ran A1 - Niamir, Aidin A1 - Odden, John A1 - Oliveira-Santos, Luiz Gustavo R. A1 - Olson, Kirk A. A1 - Patterson, Bruce D. A1 - de Paula, Rogerio Cunha A1 - Pedrotti, Luca A1 - Reineking, Bjorn A1 - Rimmler, Martin A1 - Rogers, Tracey L. A1 - Rolandsen, Christer Moe A1 - Rosenberry, Christopher S. A1 - Rubenstein, Daniel I. A1 - Safi, Kamran A1 - Said, Sonia A1 - Sapir, Nir A1 - Sawyer, Hall A1 - Schmidt, Niels Martin A1 - Selva, Nuria A1 - Sergiel, Agnieszka A1 - Shiilegdamba, Enkhtuvshin A1 - Silva, Joao Paulo A1 - Singh, Navinder A1 - Solberg, Erling J. A1 - Spiegel, Orr A1 - Strand, Olav A1 - Sundaresan, Siva A1 - Ullmann, Wiebke A1 - Voigt, Ulrich A1 - Wall, Jake A1 - Wattles, David A1 - Wikelski, Martin A1 - Wilmers, Christopher C. A1 - Wilson, John W. A1 - Wittemyer, George A1 - Zieba, Filip A1 - Zwijacz-Kozica, Tomasz A1 - Mueller, Thomas T1 - Moving in the Anthropocene BT - global reductions in terrestrial mammalian movements JF - Science N2 - Animal movement is fundamental for ecosystem functioning and species survival, yet the effects of the anthropogenic footprint on animal movements have not been estimated across species. Using a unique GPS-tracking database of 803 individuals across 57 species, we found that movements of mammals in areas with a comparatively high human footprint were on average one-half to one-third the extent of their movements in areas with a low human footprint. We attribute this reduction to behavioral changes of individual animals and to the exclusion of species with long-range movements from areas with higher human impact. Global loss of vagility alters a key ecological trait of animals that affects not only population persistence but also ecosystem processes such as predator-prey interactions, nutrient cycling, and disease transmission. Y1 - 2018 U6 - https://doi.org/10.1126/science.aam9712 SN - 0036-8075 SN - 1095-9203 VL - 359 IS - 6374 SP - 466 EP - 469 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Yenesew, Abiy A1 - Twinomuhwezi, Hannington A1 - Kiremire, Bernard T. A1 - Mbugua, Martin N. A1 - Gitu, Peter M. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - 8-Methoxyneorautenol and radical scavenging flavonoids from Erythrina abyssinica N2 - A new pterocarpan (named 8-methoxyneorautenol) was isolated from the acetone ext. of the root bark of Erythrina abyssinica. In addn., the known isoflavonoid derivs. eryvarin L, erycristagallin and shinpterocarpin were identified for the first time from the roots of this plant. The structures were detd. on the basis of spectroscopic evidence. The new compd. showed selective antimicrobial activity against Trichophyton mentagrophytes. The acetone ext. of the root bark of E. abyssinica showed radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl radical (DPPH). The pterocarpenes, 3-hydroxy-9-methoxy-10-(3,3-dimethylallyl)pterocarpene and erycristagallin, were the most active constituents of the roots of this plant and showing dose-dependent activities similar to that of the std. quercetin. [on SciFinder (R)] Y1 - 2009 UR - http://www.ajol.info/journal_index.php?jid=120&ab=bcse SN - 1011-3924 ER - TY - JOUR A1 - Penone, Caterina A1 - Allan, Eric A1 - Soliveres, Santiago A1 - Felipe-Lucia, Maria R. A1 - Gossner, Martin M. A1 - Seibold, Sebastian A1 - Simons, Nadja K. A1 - Schall, Peter A1 - van der Plas, Fons A1 - Manning, Peter A1 - Manzanedo, Ruben D. A1 - Boch, Steffen A1 - Prati, Daniel A1 - Ammer, Christian A1 - Bauhus, Juergen A1 - Buscot, Francois A1 - Ehbrecht, Martin A1 - Goldmann, Kezia A1 - Jung, Kirsten A1 - Mueller, Joerg A1 - Mueller, Joerg C. A1 - Pena, Rodica A1 - Polle, Andrea A1 - Renner, Swen C. A1 - Ruess, Liliane A1 - Schoenig, Ingo A1 - Schrumpf, Marion A1 - Solly, Emily F. A1 - Tschapka, Marco A1 - Weisser, Wolfgang W. A1 - Wubet, Tesfaye A1 - Fischer, Markus T1 - Specialisation and diversity of multiple trophic groups are promoted by different forest features JF - Ecology letters N2 - While forest management strongly influences biodiversity, it remains unclear how the structural and compositional changes caused by management affect different community dimensions (e.g. richness, specialisation, abundance or completeness) and how this differs between taxa. We assessed the effects of nine forest features (representing stand structure, heterogeneity and tree composition) on thirteen above- and belowground trophic groups of plants, animals, fungi and bacteria in 150 temperate forest plots differing in their management type. Canopy cover decreased light resources, which increased community specialisation but reduced overall diversity and abundance. Features increasing resource types and diversifying microhabitats (admixing of oaks and conifers) were important and mostly affected richness. Belowground groups responded differently to those aboveground and had weaker responses to most forest features. Our results show that we need to consider forest features rather than broad management types and highlight the importance of considering several groups and community dimensions to better inform conservation. KW - biodiversity exploratories KW - dark diversity KW - forest management KW - global change KW - land-use KW - multidiversity KW - specialisation KW - temperate forests Y1 - 2018 U6 - https://doi.org/10.1111/ele.13182 SN - 1461-023X SN - 1461-0248 VL - 22 IS - 1 SP - 170 EP - 180 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Neumann, Bernhard A1 - Horstkemper, Marianne A1 - Krüger, Wolfgang A1 - Wilkens, Martin A1 - Bohlen, Andreas A1 - Frübing, Peter A1 - Wegener, Michael A1 - Scheff, Ullrich A1 - Neher, Dieter A1 - Brehmer, Ludwig A1 - Kleinpeter, Erich A1 - Wolf, Gunter A1 - Koetz, Joachim A1 - Peter, Martin G. A1 - Senkbeil, Sigrid A1 - Meyer, Till T1 - Portal = Im Trend: Physiker und Chemiker erforschen "Soft Matter" BT - Die Potsdamer Universitätszeitung N2 - Aus dem Inhalt: Im Trend: Physiker und Chemiker erforschen „Soft Matter“ -Brandenburger Netzwerk für Existenzgründer erhält Förderung -Universität leistet Beitrag zum Romantik-Jahr -Musiksender MTV und Bryan Adams auf dem Campus T3 - Portal: Das Potsdamer Universitätsmagazin - 06/2002 Y1 - 2002 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-501441 SN - 1618-6893 VL - 2002 ER - TY - JOUR A1 - Middeldorp, Christel M. A1 - Mahajan, Anubha A1 - Horikoshi, Momoko A1 - Robertson, Neil R. A1 - Beaumont, Robin N. A1 - Bradfield, Jonathan P. A1 - Bustamante, Mariona A1 - Cousminer, Diana L. A1 - Day, Felix R. A1 - De Silva, N. Maneka A1 - Guxens, Monica A1 - Mook-Kanamori, Dennis O. A1 - St Pourcain, Beate A1 - Warrington, Nicole M. A1 - Adair, Linda S. A1 - Ahlqvist, Emma A1 - Ahluwalia, Tarunveer Singh A1 - Almgren, Peter A1 - Ang, Wei A1 - Atalay, Mustafa A1 - Auvinen, Juha A1 - Bartels, Meike A1 - Beckmann, Jacques S. A1 - Bilbao, Jose Ramon A1 - Bond, Tom A1 - Borja, Judith B. A1 - Cavadino, Alana A1 - Charoen, Pimphen A1 - Chen, Zhanghua A1 - Coin, Lachlan A1 - Cooper, Cyrus A1 - Curtin, John A. A1 - Custovic, Adnan A1 - Das, Shikta A1 - Davies, Gareth E. A1 - Dedoussis, George V. A1 - Duijts, Liesbeth A1 - Eastwood, Peter R. A1 - Eliasen, Anders U. A1 - Elliott, Paul A1 - Eriksson, Johan G. A1 - Estivill, Xavier A1 - Fadista, Joao A1 - Fedko, Iryna O. A1 - Frayling, Timothy M. A1 - Gaillard, Romy A1 - Gauderman, W. James A1 - Geller, Frank A1 - Gilliland, Frank A1 - Gilsanz, Vincente A1 - Granell, Raquel A1 - Grarup, Niels A1 - Groop, Leif A1 - Hadley, Dexter A1 - Hakonarson, Hakon A1 - Hansen, Torben A1 - Hartman, Catharina A. A1 - Hattersley, Andrew T. A1 - Hayes, M. Geoffrey A1 - Hebebrand, Johannes A1 - Heinrich, Joachim A1 - Helgeland, Oyvind A1 - Henders, Anjali K. A1 - Henderson, John A1 - Henriksen, Tine B. A1 - Hirschhorn, Joel N. A1 - Hivert, Marie-France A1 - Hocher, Berthold A1 - Holloway, John W. A1 - Holt, Patrick A1 - Hottenga, Jouke-Jan A1 - Hypponen, Elina A1 - Iniguez, Carmen A1 - Johansson, Stefan A1 - Jugessur, Astanand A1 - Kahonen, Mika A1 - Kalkwarf, Heidi J. A1 - Kaprio, Jaakko A1 - Karhunen, Ville A1 - Kemp, John P. A1 - Kerkhof, Marjan A1 - Koppelman, Gerard H. A1 - Korner, Antje A1 - Kotecha, Sailesh A1 - Kreiner-Moller, Eskil A1 - Kulohoma, Benard A1 - Kumar, Ashish A1 - Kutalik, Zoltan A1 - Lahti, Jari A1 - Lappe, Joan M. A1 - Larsson, Henrik A1 - Lehtimaki, Terho A1 - Lewin, Alexandra M. A1 - Li, Jin A1 - Lichtenstein, Paul A1 - Lindgren, Cecilia M. A1 - Lindi, Virpi A1 - Linneberg, Allan A1 - Liu, Xueping A1 - Liu, Jun A1 - Lowe, William L. A1 - Lundstrom, Sebastian A1 - Lyytikainen, Leo-Pekka A1 - Ma, Ronald C. W. A1 - Mace, Aurelien A1 - Magi, Reedik A1 - Magnus, Per A1 - Mamun, Abdullah A. A1 - Mannikko, Minna A1 - Martin, Nicholas G. A1 - Mbarek, Hamdi A1 - McCarthy, Nina S. A1 - Medland, Sarah E. A1 - Melbye, Mads A1 - Melen, Erik A1 - Mohlke, Karen L. A1 - Monnereau, Claire A1 - Morgen, Camilla S. A1 - Morris, Andrew P. A1 - Murray, Jeffrey C. A1 - Myhre, Ronny A1 - Najman, Jackob M. A1 - Nivard, Michel G. A1 - Nohr, Ellen A. A1 - Nolte, Ilja M. A1 - Ntalla, Ioanna A1 - Oberfield, Sharon E. A1 - Oken, Emily A1 - Oldehinkel, Albertine J. A1 - Pahkala, Katja A1 - Palviainen, Teemu A1 - Panoutsopoulou, Kalliope A1 - Pedersen, Oluf A1 - Pennell, Craig E. A1 - Pershagen, Goran A1 - Pitkanen, Niina A1 - Plomin, Robert A1 - Power, Christine A1 - Prasad, Rashmi B. A1 - Prokopenko, Inga A1 - Pulkkinen, Lea A1 - Raikkonen, Katri A1 - Raitakari, Olli T. A1 - Reynolds, Rebecca M. A1 - Richmond, Rebecca C. A1 - Rivadeneira, Fernando A1 - Rodriguez, Alina A1 - Rose, Richard J. A1 - Salem, Rany A1 - Santa-Marina, Loreto A1 - Saw, Seang-Mei A1 - Schnurr, Theresia M. A1 - Scott, James G. A1 - Selzam, Saskia A1 - Shepherd, John A. A1 - Simpson, Angela A1 - Skotte, Line A1 - Sleiman, Patrick M. A. A1 - Snieder, Harold A1 - Sorensen, Thorkild I. A. A1 - Standl, Marie A1 - Steegers, Eric A. P. A1 - Strachan, David P. A1 - Straker, Leon A1 - Strandberg, Timo A1 - Taylor, Michelle A1 - Teo, Yik-Ying A1 - Thiering, Elisabeth A1 - Torrent, Maties A1 - Tyrrell, Jessica A1 - Uitterlinden, Andre G. A1 - van Beijsterveldt, Toos A1 - van der Most, Peter J. A1 - van Duijn, Cornelia M. A1 - Viikari, Jorma A1 - Vilor-Tejedor, Natalia A1 - Vogelezang, Suzanne A1 - Vonk, Judith M. A1 - Vrijkotte, Tanja G. M. A1 - Vuoksimaa, Eero A1 - Wang, Carol A. A1 - Watkins, William J. A1 - Wichmann, H-Erich A1 - Willemsen, Gonneke A1 - Williams, Gail M. A1 - Wilson, James F. A1 - Wray, Naomi R. A1 - Xu, Shujing A1 - Xu, Cheng-Jian A1 - Yaghootkar, Hanieh A1 - Yi, Lu A1 - Zafarmand, Mohammad Hadi A1 - Zeggini, Eleftheria A1 - Zemel, Babette S. A1 - Hinney, Anke A1 - Lakka, Timo A. A1 - Whitehouse, Andrew J. O. A1 - Sunyer, Jordi A1 - Widen, Elisabeth E. A1 - Feenstra, Bjarke A1 - Sebert, Sylvain A1 - Jacobsson, Bo A1 - Njolstad, Pal R. A1 - Stoltenberg, Camilla A1 - Smith, George Davey A1 - Lawlor, Debbie A. A1 - Paternoster, Lavinia A1 - Timpson, Nicholas J. A1 - Ong, Ken K. A1 - Bisgaard, Hans A1 - Bonnelykke, Klaus A1 - Jaddoe, Vincent W. V. A1 - Tiemeier, Henning A1 - Jarvelin, Marjo-Riitta A1 - Evans, David M. A1 - Perry, John R. B. A1 - Grant, Struan F. A. A1 - Boomsma, Dorret I. A1 - Freathy, Rachel M. A1 - McCarthy, Mark I. A1 - Felix, Janine F. T1 - The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia BT - design, results and future prospects JF - European journal of epidemiology N2 - The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites. KW - Genetics KW - Consortium KW - Childhood traits and disorders KW - Longitudinal Y1 - 2019 U6 - https://doi.org/10.1007/s10654-019-00502-9 SN - 0393-2990 SN - 1573-7284 VL - 34 IS - 3 SP - 279 EP - 300 PB - Springer CY - Dordrecht ER - TY - GEN A1 - Peter, Martin G. A1 - Boldt, Peter C. A1 - Niederstein, Yvonne A1 - Peter-Katalinić, Jasna T1 - Synthesen von Galactose-Cluster-haltigen Steroid-Derivaten N2 - The synthesis of galactose clusters that are linked to a steroid moiety by a peptide-like spacer unit is described. The galactose cluster is obtained by Koenigs-Knorr glycosylation of TRIS-Gly-Fmoc (2b) under Helferich conditions. Peptide and ester bonds are formed after activation of carboxylic acids as diphenylthiophene dioxide (TDO) esters. 6a is synthesized in a convergent way by coupling of (Ac4Gal)3-TRIS-Gly (3e) with cholesteryl TDO succinate (5b). Coupling of (Ac4Gal)3-TRIS-Gly hydrogen succinate (3f) with Gly-O-Chol (5d) by means of EEDQ yields 6d. Reaction of (Ac4Gal)3-TRIS-Gly-SUCC-O-TDO (3g) with 25-hydroxycholesterol leads in a linear sequence to the oxysterol derivative 6f. Selective cleavage of the acetyl groups from galactose units yields the known compound 6b and the new derivatives 6e and 6g. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 042 KW - Glycoconjugates KW - Galactosides KW - Steroid esters KW - Amphiphiles KW - Glycopeptides Y1 - 1990 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16783 ER - TY - JOUR A1 - Teriaca, Luca A1 - Andretta, Vincenzo A1 - Auchere, Frederic A1 - Brown, Charles M. A1 - Buchlin, Eric A1 - Cauzzi, Gianna A1 - Culhane, J. Len A1 - Curdt, Werner A1 - Davila, Joseph M. A1 - Del Zanna, Giulio A1 - Doschek, George A. A1 - Fineschi, Silvano A1 - Fludra, Andrzej A1 - Gallagher, Peter T. A1 - Green, Lucie A1 - Harra, Louise K. A1 - Imada, Shinsuke A1 - Innes, Davina A1 - Kliem, Bernhard A1 - Korendyke, Clarence A1 - Mariska, John T. A1 - Martinez-Pillet, Valentin A1 - Parenti, Susanna A1 - Patsourakos, Spiros A1 - Peter, Hardi A1 - Poletto, Luca A1 - Rutten, Robert J. A1 - Schuehle, Udo A1 - Siemer, Martin A1 - Shimizu, Toshifumi A1 - Socas-Navarro, Hector A1 - Solanki, Sami K. A1 - Spadaro, Daniele A1 - Trujillo-Bueno, Javier A1 - Tsuneta, Saku A1 - Dominguez, Santiago Vargas A1 - Vial, Jean-Claude A1 - Walsh, Robert A1 - Warren, Harry P. A1 - Wiegelmann, Thomas A1 - Winter, Berend A1 - Young, Peter T1 - LEMUR large european module for solar ultraviolet research JF - Experimental astronomy : an international journal on astronomical instrumentation and data analysis N2 - The solar outer atmosphere is an extremely dynamic environment characterized by the continuous interplay between the plasma and the magnetic field that generates and permeates it. Such interactions play a fundamental role in hugely diverse astrophysical systems, but occur at scales that cannot be studied outside the solar system. Understanding this complex system requires concerted, simultaneous solar observations from the visible to the vacuum ultraviolet (VUV) and soft X-rays, at high spatial resolution (between 0.1'' and 0.3''), at high temporal resolution (on the order of 10 s, i.e., the time scale of chromospheric dynamics), with a wide temperature coverage (0.01 MK to 20 MK, from the chromosphere to the flaring corona), and the capability of measuring magnetic fields through spectropolarimetry at visible and near-infrared wavelengths. Simultaneous spectroscopic measurements sampling the entire temperature range are particularly important. These requirements are fulfilled by the Japanese Solar-C mission (Plan B), composed of a spacecraft in a geosynchronous orbit with a payload providing a significant improvement of imaging and spectropolarimetric capabilities in the UV, visible, and near-infrared with respect to what is available today and foreseen in the near future. The Large European Module for solar Ultraviolet Research (LEMUR), described in this paper, is a large VUV telescope feeding a scientific payload of high-resolution imaging spectrographs and cameras. LEMUR consists of two major components: a VUV solar telescope with a 30 cm diameter mirror and a focal length of 3.6 m, and a focal-plane package composed of VUV spectrometers covering six carefully chosen wavelength ranges between 170 and 1270 . The LEMUR slit covers 280'' on the Sun with 0.14'' per pixel sampling. In addition, LEMUR is capable of measuring mass flows velocities (line shifts) down to 2 km s (-aEuro parts per thousand 1) or better. LEMUR has been proposed to ESA as the European contribution to the Solar C mission. KW - Sun: atmosphere KW - Space vehicles: instruments KW - Techniques: spectroscopy KW - ESA cosmic vision Y1 - 2012 U6 - https://doi.org/10.1007/s10686-011-9274-x SN - 0922-6435 VL - 34 IS - 2 SP - 273 EP - 309 PB - Springer CY - Dordrecht ER - TY - GEN A1 - Gorski, Mathias A1 - Jung, Bettina A1 - Li, Yong A1 - Matias-Garcia, Pamela R. A1 - Wuttke, Matthias A1 - Coassin, Stefan A1 - Thio, Chris H. L. A1 - Kleber, Marcus E. A1 - Winkler, Thomas W. A1 - Wanner, Veronika A1 - Chai, Jin-Fang A1 - Chu, Audrey Y. A1 - Cocca, Massimiliano A1 - Feitosa, Mary F. A1 - Ghasemi, Sahar A1 - Hoppmann, Anselm A1 - Horn, Katrin A1 - Li, Man A1 - Nutile, Teresa A1 - Scholz, Markus A1 - Sieber, Karsten B. A1 - Teumer, Alexander A1 - Tin, Adrienne A1 - Wang, Judy A1 - Tayo, Bamidele O. A1 - Ahluwalia, Tarunveer S. A1 - Almgren, Peter A1 - Bakker, Stephan J. L. A1 - Banas, Bernhard A1 - Bansal, Nisha A1 - Biggs, Mary L. A1 - Boerwinkle, Eric A1 - Böttinger, Erwin A1 - Brenner, Hermann A1 - Carroll, Robert J. A1 - Chalmers, John A1 - Chee, Miao-Li A1 - Chee, Miao-Ling A1 - Cheng, Ching-Yu A1 - Coresh, Josef A1 - de Borst, Martin H. A1 - Degenhardt, Frauke A1 - Eckardt, Kai-Uwe A1 - Endlich, Karlhans A1 - Franke, Andre A1 - Freitag-Wolf, Sandra A1 - Gampawar, Piyush A1 - Gansevoort, Ron T. A1 - Ghanbari, Mohsen A1 - Gieger, Christian A1 - Hamet, Pavel A1 - Ho, Kevin A1 - Hofer, Edith A1 - Holleczek, Bernd A1 - Foo, Valencia Hui Xian A1 - Hutri-Kahonen, Nina A1 - Hwang, Shih-Jen A1 - Ikram, M. Arfan A1 - Josyula, Navya Shilpa A1 - Kahonen, Mika A1 - Khor, Chiea-Chuen A1 - Koenig, Wolfgang A1 - Kramer, Holly A1 - Kraemer, Bernhard K. A1 - Kuehnel, Brigitte A1 - Lange, Leslie A. A1 - Lehtimaki, Terho A1 - Lieb, Wolfgang A1 - Loos, Ruth J. F. A1 - Lukas, Mary Ann A1 - Lyytikainen, Leo-Pekka A1 - Meisinger, Christa A1 - Meitinger, Thomas A1 - Melander, Olle A1 - Milaneschi, Yuri A1 - Mishra, Pashupati P. A1 - Mononen, Nina A1 - Mychaleckyj, Josyf C. A1 - Nadkarni, Girish N. A1 - Nauck, Matthias A1 - Nikus, Kjell A1 - Ning, Boting A1 - Nolte, Ilja M. A1 - O'Donoghue, Michelle L. A1 - Orho-Melander, Marju A1 - Pendergrass, Sarah A. A1 - Penninx, Brenda W. J. H. A1 - Preuss, Michael H. A1 - Psaty, Bruce M. A1 - Raffield, Laura M. A1 - Raitakari, Olli T. A1 - Rettig, Rainer A1 - Rheinberger, Myriam A1 - Rice, Kenneth M. A1 - Rosenkranz, Alexander R. A1 - Rossing, Peter A1 - Rotter, Jerome A1 - Sabanayagam, Charumathi A1 - Schmidt, Helena A1 - Schmidt, Reinhold A1 - Schoettker, Ben A1 - Schulz, Christina-Alexandra A1 - Sedaghat, Sanaz A1 - Shaffer, Christian M. A1 - Strauch, Konstantin A1 - Szymczak, Silke A1 - Taylor, Kent D. A1 - Tremblay, Johanne A1 - Chaker, Layal A1 - van der Harst, Pim A1 - van der Most, Peter J. A1 - Verweij, Niek A1 - Voelker, Uwe A1 - Waldenberger, Melanie A1 - Wallentin, Lars A1 - Waterworth, Dawn M. A1 - White, Harvey D. A1 - Wilson, James G. A1 - Wong, Tien-Yin A1 - Woodward, Mark A1 - Yang, Qiong A1 - Yasuda, Masayuki A1 - Yerges-Armstrong, Laura M. A1 - Zhang, Yan A1 - Snieder, Harold A1 - Wanner, Christoph A1 - Boger, Carsten A. A1 - Kottgen, Anna A1 - Kronenberg, Florian A1 - Pattaro, Cristian A1 - Heid, Iris M. T1 - Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline T2 - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät N2 - Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function. T3 - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät - 19 KW - acute kidney injury KW - end-stage kidney disease KW - genome-wide association KW - study KW - rapid eGFRcrea decline Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-565379 IS - 19 ER - TY - JOUR A1 - Gorski, Mathias A1 - Jung, Bettina A1 - Li, Yong A1 - Matias-Garcia, Pamela R. A1 - Wuttke, Matthias A1 - Coassin, Stefan A1 - Thio, Chris H. L. A1 - Kleber, Marcus E. A1 - Winkler, Thomas W. A1 - Wanner, Veronika A1 - Chai, Jin-Fang A1 - Chu, Audrey Y. A1 - Cocca, Massimiliano A1 - Feitosa, Mary F. A1 - Ghasemi, Sahar A1 - Hoppmann, Anselm A1 - Horn, Katrin A1 - Li, Man A1 - Nutile, Teresa A1 - Scholz, Markus A1 - Sieber, Karsten B. A1 - Teumer, Alexander A1 - Tin, Adrienne A1 - Wang, Judy A1 - Tayo, Bamidele O. A1 - Ahluwalia, Tarunveer S. A1 - Almgren, Peter A1 - Bakker, Stephan J. L. A1 - Banas, Bernhard A1 - Bansal, Nisha A1 - Biggs, Mary L. A1 - Boerwinkle, Eric A1 - Böttinger, Erwin A1 - Brenner, Hermann A1 - Carroll, Robert J. A1 - Chalmers, John A1 - Chee, Miao-Li A1 - Chee, Miao-Ling A1 - Cheng, Ching-Yu A1 - Coresh, Josef A1 - de Borst, Martin H. A1 - Degenhardt, Frauke A1 - Eckardt, Kai-Uwe A1 - Endlich, Karlhans A1 - Franke, Andre A1 - Freitag-Wolf, Sandra A1 - Gampawar, Piyush A1 - Gansevoort, Ron T. A1 - Ghanbari, Mohsen A1 - Gieger, Christian A1 - Hamet, Pavel A1 - Ho, Kevin A1 - Hofer, Edith A1 - Holleczek, Bernd A1 - Foo, Valencia Hui Xian A1 - Hutri-Kahonen, Nina A1 - Hwang, Shih-Jen A1 - Ikram, M. Arfan A1 - Josyula, Navya Shilpa A1 - Kahonen, Mika A1 - Khor, Chiea-Chuen A1 - Koenig, Wolfgang A1 - Kramer, Holly A1 - Kraemer, Bernhard K. A1 - Kuehnel, Brigitte A1 - Lange, Leslie A. A1 - Lehtimaki, Terho A1 - Lieb, Wolfgang A1 - Loos, Ruth J. F. A1 - Lukas, Mary Ann A1 - Lyytikainen, Leo-Pekka A1 - Meisinger, Christa A1 - Meitinger, Thomas A1 - Melander, Olle A1 - Milaneschi, Yuri A1 - Mishra, Pashupati P. A1 - Mononen, Nina A1 - Mychaleckyj, Josyf C. A1 - Nadkarni, Girish N. A1 - Nauck, Matthias A1 - Nikus, Kjell A1 - Ning, Boting A1 - Nolte, Ilja M. A1 - O'Donoghue, Michelle L. A1 - Orho-Melander, Marju A1 - Pendergrass, Sarah A. A1 - Penninx, Brenda W. J. H. A1 - Preuss, Michael H. A1 - Psaty, Bruce M. A1 - Raffield, Laura M. A1 - Raitakari, Olli T. A1 - Rettig, Rainer A1 - Rheinberger, Myriam A1 - Rice, Kenneth M. A1 - Rosenkranz, Alexander R. A1 - Rossing, Peter A1 - Rotter, Jerome A1 - Sabanayagam, Charumathi A1 - Schmidt, Helena A1 - Schmidt, Reinhold A1 - Schoettker, Ben A1 - Schulz, Christina-Alexandra A1 - Sedaghat, Sanaz A1 - Shaffer, Christian M. A1 - Strauch, Konstantin A1 - Szymczak, Silke A1 - Taylor, Kent D. A1 - Tremblay, Johanne A1 - Chaker, Layal A1 - van der Harst, Pim A1 - van der Most, Peter J. A1 - Verweij, Niek A1 - Voelker, Uwe A1 - Waldenberger, Melanie A1 - Wallentin, Lars A1 - Waterworth, Dawn M. A1 - White, Harvey D. A1 - Wilson, James G. A1 - Wong, Tien-Yin A1 - Woodward, Mark A1 - Yang, Qiong A1 - Yasuda, Masayuki A1 - Yerges-Armstrong, Laura M. A1 - Zhang, Yan A1 - Snieder, Harold A1 - Wanner, Christoph A1 - Boger, Carsten A. A1 - Kottgen, Anna A1 - Kronenberg, Florian A1 - Pattaro, Cristian A1 - Heid, Iris M. T1 - Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline JF - Kidney international : official journal of the International Society of Nephrology N2 - Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function. KW - acute kidney injury KW - end-stage kidney disease KW - genome-wide association KW - study KW - rapid eGFRcrea decline Y1 - 2020 U6 - https://doi.org/10.1016/j.kint.2020.09.030 SN - 0085-2538 SN - 1523-1755 VL - 99 IS - 4 SP - 926 EP - 939 PB - Elsevier CY - New York ER - TY - JOUR A1 - Dengler, Jürgen A1 - Wagner, Viktoria A1 - Dembicz, Iwona A1 - Garcia-Mijangos, Itziar A1 - Naqinezhad, Alireza A1 - Boch, Steffen A1 - Chiarucci, Alessandro A1 - Conradi, Timo A1 - Filibeck, Goffredo A1 - Guarino, Riccardo A1 - Janisova, Monika A1 - Steinbauer, Manuel J. A1 - Acic, Svetlana A1 - Acosta, Alicia T. R. A1 - Akasaka, Munemitsu A1 - Allers, Marc-Andre A1 - Apostolova, Iva A1 - Axmanova, Irena A1 - Bakan, Branko A1 - Baranova, Alina A1 - Bardy-Durchhalter, Manfred A1 - Bartha, Sandor A1 - Baumann, Esther A1 - Becker, Thomas A1 - Becker, Ute A1 - Belonovskaya, Elena A1 - Bengtsson, Karin A1 - Benito Alonso, Jose Luis A1 - Berastegi, Asun A1 - Bergamini, Ariel A1 - Bonini, Ilaria A1 - Bruun, Hans Henrik A1 - Budzhak, Vasyl A1 - Bueno, Alvaro A1 - Antonio Campos, Juan A1 - Cancellieri, Laura A1 - Carboni, Marta A1 - Chocarro, Cristina A1 - Conti, Luisa A1 - Czarniecka-Wiera, Marta A1 - De Frenne, Pieter A1 - Deak, Balazs A1 - Didukh, Yakiv P. A1 - Diekmann, Martin A1 - Dolnik, Christian A1 - Dupre, Cecilia A1 - Ecker, Klaus A1 - Ermakov, Nikolai A1 - Erschbamer, Brigitta A1 - Escudero, Adrian A1 - Etayo, Javier A1 - Fajmonova, Zuzana A1 - Felde, Vivian A. A1 - Fernandez Calzado, Maria Rosa A1 - Finckh, Manfred A1 - Fotiadis, Georgios A1 - Fracchiolla, Mariano A1 - Ganeva, Anna A1 - Garcia-Magro, Daniel A1 - Gavilan, Rosario G. A1 - Germany, Markus A1 - Giladi, Itamar A1 - Gillet, Francois A1 - Giusso del Galdo, Gian Pietro A1 - Gonzalez, Jose M. A1 - Grytnes, John-Arvid A1 - Hajek, Michal A1 - Hajkova, Petra A1 - Helm, Aveliina A1 - Herrera, Mercedes A1 - Hettenbergerova, Eva A1 - Hobohm, Carsten A1 - Huellbusch, Elisabeth M. A1 - Ingerpuu, Nele A1 - Jandt, Ute A1 - Jeltsch, Florian A1 - Jensen, Kai A1 - Jentsch, Anke A1 - Jeschke, Michael A1 - Jimenez-Alfaro, Borja A1 - Kacki, Zygmunt A1 - Kakinuma, Kaoru A1 - Kapfer, Jutta A1 - Kavgaci, Ali A1 - Kelemen, Andras A1 - Kiehl, Kathrin A1 - Koyama, Asuka A1 - Koyanagi, Tomoyo F. A1 - Kozub, Lukasz A1 - Kuzemko, Anna A1 - Kyrkjeeide, Magni Olsen A1 - Landi, Sara A1 - Langer, Nancy A1 - Lastrucci, Lorenzo A1 - Lazzaro, Lorenzo A1 - Lelli, Chiara A1 - Leps, Jan A1 - Loebel, Swantje A1 - Luzuriaga, Arantzazu L. A1 - Maccherini, Simona A1 - Magnes, Martin A1 - Malicki, Marek A1 - Marceno, Corrado A1 - Mardari, Constantin A1 - Mauchamp, Leslie A1 - May, Felix A1 - Michelsen, Ottar A1 - Mesa, Joaquin Molero A1 - Molnar, Zsolt A1 - Moysiyenko, Ivan Y. A1 - Nakaga, Yuko K. A1 - Natcheva, Rayna A1 - Noroozi, Jalil A1 - Pakeman, Robin J. A1 - Palpurina, Salza A1 - Partel, Meelis A1 - Paetsch, Ricarda A1 - Pauli, Harald A1 - Pedashenko, Hristo A1 - Peet, Robert K. A1 - Pielech, Remigiusz A1 - Pipenbaher, Natasa A1 - Pirini, Chrisoula A1 - Pleskova, Zuzana A1 - Polyakova, Mariya A. A1 - Prentice, Honor C. A1 - Reinecke, Jennifer A1 - Reitalu, Triin A1 - Pilar Rodriguez-Rojo, Maria A1 - Rolecek, Jan A1 - Ronkin, Vladimir A1 - Rosati, Leonardo A1 - Rosen, Ejvind A1 - Ruprecht, Eszter A1 - Rusina, Solvita A1 - Sabovljevic, Marko A1 - Maria Sanchez, Ana A1 - Savchenko, Galina A1 - Schuhmacher, Oliver A1 - Skornik, Sonja A1 - Sperandii, Marta Gaia A1 - Staniaszek-Kik, Monika A1 - Stevanovic-Dajic, Zora A1 - Stock, Marin A1 - Suchrow, Sigrid A1 - Sutcliffe, Laura M. E. A1 - Swacha, Grzegorz A1 - Sykes, Martin A1 - Szabo, Anna A1 - Talebi, Amir A1 - Tanase, Catalin A1 - Terzi, Massimo A1 - Tolgyesi, Csaba A1 - Torca, Marta A1 - Torok, Peter A1 - Tothmeresz, Bela A1 - Tsarevskaya, Nadezda A1 - Tsiripidis, Ioannis A1 - Tzonev, Rossen A1 - Ushimaru, Atushi A1 - Valko, Orsolya A1 - van der Maarel, Eddy A1 - Vanneste, Thomas A1 - Vashenyak, Iuliia A1 - Vassilev, Kiril A1 - Viciani, Daniele A1 - Villar, Luis A1 - Virtanen, Risto A1 - Kosic, Ivana Vitasovic A1 - Wang, Yun A1 - Weiser, Frank A1 - Went, Julia A1 - Wesche, Karsten A1 - White, Hannah A1 - Winkler, Manuela A1 - Zaniewski, Piotr T. A1 - Zhang, Hui A1 - Ziv, Yaron A1 - Znamenskiy, Sergey A1 - Biurrun, Idoia T1 - GrassPlot - a database of multi-scale plant diversity in Palaearctic grasslands JF - Phytocoenologia N2 - GrassPlot is a collaborative vegetation-plot database organised by the Eurasian Dry Grassland Group (EDGG) and listed in the Global Index of Vegetation-Plot Databases (GIVD ID EU-00-003). GrassPlot collects plot records (releves) from grasslands and other open habitats of the Palaearctic biogeographic realm. It focuses on precisely delimited plots of eight standard grain sizes (0.0001; 0.001;... 1,000 m(2)) and on nested-plot series with at least four different grain sizes. The usage of GrassPlot is regulated through Bylaws that intend to balance the interests of data contributors and data users. The current version (v. 1.00) contains data for approximately 170,000 plots of different sizes and 2,800 nested-plot series. The key components are richness data and metadata. However, most included datasets also encompass compositional data. About 14,000 plots have near-complete records of terricolous bryophytes and lichens in addition to vascular plants. At present, GrassPlot contains data from 36 countries throughout the Palaearctic, spread across elevational gradients and major grassland types. GrassPlot with its multi-scale and multi-taxon focus complements the larger international vegetationplot databases, such as the European Vegetation Archive (EVA) and the global database " sPlot". Its main aim is to facilitate studies on the scale-and taxon-dependency of biodiversity patterns and drivers along macroecological gradients. GrassPlot is a dynamic database and will expand through new data collection coordinated by the elected Governing Board. We invite researchers with suitable data to join GrassPlot. Researchers with project ideas addressable with GrassPlot data are welcome to submit proposals to the Governing Board. KW - biodiversity KW - European Vegetation Archive (EVA) KW - Eurasian Dry Grassland Group (EDGG) KW - grassland vegetation KW - GrassPlot KW - macroecology KW - multi-taxon KW - nested plot KW - scale-dependence KW - species-area relationship (SAR) KW - sPlot KW - vegetation-plot database Y1 - 2018 U6 - https://doi.org/10.1127/phyto/2018/0267 SN - 0340-269X VL - 48 IS - 3 SP - 331 EP - 347 PB - Cramer CY - Stuttgart ER - TY - BOOK A1 - Mientus, Lukas A1 - Klempin, Christiane A1 - Nowak, Anna A1 - Wyss, Corinne A1 - Aufschnaiter, Claudia von A1 - Faix, Ann-Christin A1 - te Poel, Kathrin A1 - Wahbe, Nadia A1 - Pieper, Martin A1 - Höller, Katharina A1 - Kallenbach, Lea A1 - Förster, Magdalena A1 - Redecker, Anke A1 - Dick, Mirjam A1 - Holle, Jörg A1 - Schneider, Edina A1 - Rehfeldt, Daniel A1 - Brauns, Sarah A1 - Abels, Simone A1 - Ferencik-Lehmkuhl, Daria A1 - Fränkel, Silvia A1 - Frohn, Julia A1 - Liebsch, Ann-Catherine A1 - Pech, Detlef A1 - Schreier, Pascal A1 - Jessen, Moiken A1 - Großmann, Uta A1 - Skintey, Lesya A1 - Voerkel, Paul A1 - Vaz Ferreira, Mergenfel A. A1 - Zimmermann, Jan-Simon A1 - Buddeberg, Magdalena A1 - Henke, Vanessa A1 - Hornberg, Sabine A1 - Völschow, Yvette A1 - Warrelmann, Julia-Nadine A1 - Malek, Jennifer A1 - Tinnefeld, Anja A1 - Schmidt, Peggy A1 - Bauer, Tobias A1 - Jänisch, Christopher A1 - Spitzer, Lisa A1 - Franken, Nadine A1 - Degeling, Maria A1 - Preisfeld, Angelika A1 - Meier, Jana A1 - Küth, Simon A1 - Scholl, Daniel A1 - Vogelsang, Christoph A1 - Watson, Christina A1 - Weißbach, Anna A1 - Kulgemeyer, Christoph A1 - Oetken, Mandy A1 - Gorski, Sebastian A1 - Kubsch, Marcus A1 - Sorge, Stefan A1 - Wulff, Peter A1 - Fellenz, Carolin D. A1 - Schnell, Susanne A1 - Larisch, Cathleen A1 - Kaiser, Franz A1 - Knott, Christina A1 - Reimer, Stefanie A1 - Stegmüller, Nathalie A1 - Boukrayâa Trabelsi, Kathrin A1 - Schißlbauer, Franziska A1 - Lemberger, Lukas A1 - Barth, Ulrike A1 - Wiehl, Angelika A1 - Rogge, Tim A1 - Böhnke, Anja A1 - Dietz, Dennis A1 - Großmann, Leroy A1 - Wienmeister, Annett A1 - Zoppke, Till A1 - Jiang, Lisa A1 - Grünbauer, Stephanie A1 - Ostersehlt, Dörte A1 - Peukert, Sophia A1 - Schäfer, Christoph A1 - Löbig, Anna A1 - Bröll, Leena A1 - Brandt, Birgit A1 - Breuer, Meike A1 - Dausend, Henriette A1 - Krelle, Michael A1 - Andersen, Gesine A1 - Falke, Sascha A1 - Kindermann-Güzel, Kristin A1 - Körner, Katrina A1 - Lottermoser, Lisa-Marie A1 - Pügner, Kati A1 - Sonnenburg, Nadine A1 - Akarsu, Selim A1 - Rechl, Friederike A1 - Gadinger, Laureen A1 - Heinze, Lena A1 - Wittmann, Eveline A1 - Franke, Manuela A1 - Lachmund, Anne-Marie A1 - Böttger, Julia A1 - Hannover, Bettina A1 - Behrendt, Renata A1 - Conty, Valentina A1 - Grundmann, Stephanie A1 - Ghassemi, Novid A1 - Opitz, Ben A1 - Brämer, Martin A1 - Gasparjan, David A1 - Sambanis, Michaela A1 - Köster, Hilde A1 - Lücke, Martin A1 - Nordmeier, Volkhard A1 - Schaal, Sonja A1 - Haberbosch, Maximilian A1 - Meissner, Maren A1 - Schaal, Steffen A1 - Brüchner, Melanie A1 - Riehle, Tamara A1 - Leopold, Bengta Marie A1 - Gerlach, Susanne A1 - Rau-Patschke, Sarah A1 - Skorsetz, Nina A1 - Weber, Nadine A1 - Damköhler, Jens A1 - Elsholz, Markus A1 - Trefzger, Thomas A1 - Lewek, Tobias A1 - Borowski, Andreas ED - Mientus, Lukas ED - Klempin, Christiane ED - Nowak, Anna T1 - Reflexion in der Lehrkräftebildung BT - Empirisch – Phasenübergreifend – Interdisziplinär T3 - Potsdamer Beiträge für Lehrkräftebildung und Bildungsforschung N2 - Reflexion ist eine Schlüsselkategorie für die professionelle Entwicklung von Lehrkräften, welche als Ausbildungsziel in den Bildungsstandards für die Lehrkräftebildung verankert ist. Eine Verstetigung universitär geprägter Forschung und Modellierung in der praxisnahen Anwendung im schulischen Kontext bietet Potentiale nachhaltiger Professionalisierung. Die Stärkung reflexionsbezogener Kompetenzen durch Empirie und Anwendung scheint eine phasenübergreifende Herausforderung der Lehrkräftebildung zu sein, die es zu bewältigen gilt. Ziele des Tagungsbandes Reflexion in der Lehrkräftebildung sind eine theoretische Schärfung des Konzeptes „Reflexive Professionalisierung“ und der Austausch über Fragen der Einbettung wirksamer reflexionsbezogener Lerngelegenheiten in die Lehrkräftebildung. Forschende und Lehrende der‚ drei Phasen (Studium, Referendariat sowie Fort- und Weiterbildung) der Lehrkräftebildung stellen Lehrkonzepte und Forschungsprojekte zum Thema Reflexion in der Lehrkräftebildung vor und diskutieren diese. Gemeinsam mit Teilnehmenden aller Phasen und von verschiedenen Standorten der Lehrkräftebildung werden zukünftige Herausforderungen identifiziert und Lösungsansätze herausgearbeitet. T3 - Potsdamer Beiträge zur Lehrkräftebildung und Bildungsforschung - 4 KW - Reflexion KW - Lehrkräftebildung KW - Reflexionskompetenz KW - Reflexivität KW - Feedback KW - Reflection KW - Teacher Education KW - Reflection Skills KW - Reflexivity KW - Feedback Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-591717 SN - 978-3-86956-566-8 SN - 2626-3556 SN - 2626-4722 IS - 4 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - THES A1 - Bahrke, Sven A1 - Einarsson, Jon M. A1 - Gislason, Johannes A1 - Haebel, Sophie A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Characterization of chitooligosaccharides by mass spectrometry Y1 - 2003 SN - 82-47-15901-5 ER - TY - JOUR A1 - Rusu, Viorel Marin A1 - Ng, C. H. A1 - Wilke, Max A1 - Tiersch, Brigitte A1 - Fratzl, Peter A1 - Peter, Martin G. T1 - Size-controlled hydroxyapatite nanoparticles as self-organized organic-in organic composite materials N2 - This paper presents some results concerning the size-controlled hydroxyapatite nanoparticles obtained in aqueous media in a biopolymer matrix from soluble precursors salts. Taking the inspiration from nature, where composite materials made of a polymer matrix and inorganic fillers are often found, e.g. bone, shell of crustaceans, shell of eggs, etc., the feasibility on making composite materials containing chitosan and nanosized hydroxyapatite was investigated. A stepwise co-precipitation approach was used to obtain different types of composites by means of different ratio between components. The synthesis of hydroxyapatite was carried out in the chitosan matrix from calcium chloride and sodium dihydrogenphosphate in alkaline solutions at moderate pH of 10-11 for 24 h. Our research is focused on studying and understanding the structure of this class of composites, aiming at the development of novel materials, controlled at the nanolevel scale. The X-ray diffraction technique was employed in order to study the kinetic of hydroxyapatite formation in the chitosan matrix as well as to determine the HAp crystallite sizes in the composite samples. The hydroxyapatite synthesized using this route was found to be nano-sized (15-50nm). Moreover, applying an original approach to analyze the (002) XRD diffraction peak profile of hydroxyapatite by using a sum of two Gauss functions, the bimodal distribution of nanosized hydroxyapatite within the chitosan matrix was revealed. Two types of size distribution domains such as cluster-like (between 200 and 400 nm), which are the habitat of "small" hydroxyapatite nanocrystallites and scattered-like, which are the habitat of "large" hydroxyapatite nanocrystallites was probed by TEM and CSLM. The structural features of composites suggest that self-assembly processes might be involved. The composites contain nanosized hydroxyapatite with structural features close to those of biological apatites that make them attractive for bone tissue engineering applications. (c) 2005 Elsevier Ltd. All rights reserved Y1 - 2005 SN - 0142-9612 ER - TY - GEN A1 - Peter, Martin G. A1 - Andersen, Svend Olav A1 - Hartmann, Rudolf A1 - Miessner, Merle A1 - Roepstorff, Peter T1 - Catecholamine-protein conjugates : isolation of 4-phenylphenoxazin-2-ones from oxidative coupling of N-acetyldopamine with alipathic amino acids N2 - 4-Phenylphenoxazinones were isolated after biomimetic oxidation, using diphenoloxidases of insect cuticle, mushroom tyrosinase, or after autoxidation of N-acetyldopamine (Image ) in the presence of β-alanine, β-alanine methyl ester or N-acetyl-L-lysine. They are formed presumably by addition of 2-aminoalkyl-5-alkylphenols to the o-quinone of biphenyltetrol which, in turn, arises from oxidative coupling of. The structures of present the first examples for the assembly of reasonably stable intermediates in the rather complex process of chemical modifications of aliphatic amino acid residues by o-quinones. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 062 Y1 - 1992 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-17571 ER - TY - GEN A1 - Peter, Martin G. A1 - Stupp, Hans-Peter A1 - Lentes, Klaus-Ulrich T1 - Umkehr der Enantioselektivität bei der enzymatischen Hydrolyse von Juvenilhormon als Ergebnis einer Proteinfraktionierung N2 - Aus dem Inhalt: Die Juvenilhormone 1a-c werden im Blut von Insekten enzymatisch zu den biologisch inaktiven Sluren hydrolysiert. Bei der Hydrolyse von racemischem 1c im Blut der Wanderheuschrecke Locusta migratoria wird ein Umsatz von 40-60% erreicht. Das unumgesetzte Edukt enthällt einen Überschuß an natürlich konfiguriertem (10R)-1c (e.e. 47.2%). Wir konnten zeigen, daß das in der Hämolymphe vorhandene Hormon-Bindungsprotein bevorzugt mit (10R)- 1c assoziiert. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 052 Y1 - 1983 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-17001 ER - TY - JOUR A1 - Andersen, S. O. A1 - Peter, Martin G. A1 - Roepstorff, Peter T1 - Cuticular sclerotization in insects Y1 - 1996 ER - TY - JOUR A1 - Haebel, Sophie A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Mass spectrometry of chitooligosaccharides Y1 - 1997 SN - 88-86889- 01-1 ER - TY - JOUR A1 - Cederkvist, F. Henning A1 - Zamfir, Alina D. A1 - Bahrke, Sven A1 - Eijsink, Vincent G. H. A1 - Sorlie, Morten A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Identification of a high-affinity-binding oligosaccharide by (+) nanoelectrospray quadrupole time-of-flight tandem mass spectrometry of a noncovalent enzyme-ligand complex Y1 - 2006 UR - http://www3.interscience.wiley.com/cgi-bin/jhome/26737/ U6 - https://doi.org/10.1002/anie.200503168 SN - 1433-7851 ER - TY - JOUR A1 - Selting, Margret A1 - Auer, Peter A1 - Barth-Weingarten, Dagmar A1 - Bergmann, Jörg A1 - Bergmann, Pia A1 - Birkner, Karin A1 - Couper-Kuhlen, Elizabeth A1 - Deppermann, Arnulf A1 - Gilles, Peter A1 - Günthner, Susanne A1 - Hartung, Martin A1 - Kern, Friederike A1 - Mertzlufft, Christine A1 - Meyer, Christian A1 - Morek, Miriam A1 - Oberzaucher, Frank A1 - Peters, Jörg A1 - Quasthoff, Uta A1 - Schütte, Wilfried A1 - Stukenbrock, Anja A1 - Uhmann, Susanne T1 - Gesprächsanalytisches Transkriptionssystem 2 (GAT 2) Y1 - 2009 UR - http://www.gespraechsforschung-ozs.de/heft2009/px-gat2.pdf (12.9.13) SN - 1617-1837 ER - TY - CHAP A1 - Hofuku, Yayoi A1 - Cho, Shinya A1 - Nishida, Tomohiro A1 - Kanemune, Susumu A1 - Linck, Barbara A1 - Kim, Seungyon A1 - Park, Seongbin A1 - Vaníček, Jiří A1 - Gujberová, Monika A1 - Tomcsányi, Peter A1 - Dagiene, Valentina A1 - Jevsikova, Tatjana A1 - Schulte, Carsten A1 - Sentance, Sue A1 - Thota, Neena A1 - Gülbahar, Yasemin A1 - İlkhan, Mustafa A1 - Kilis, Selcan A1 - Arslan, Okan A1 - Nakano, Yoshiaki A1 - Izutsu, Katsunobu A1 - Lessner, Daniel A1 - Reffay, Christophe A1 - Miled, Mahdi A1 - Ortiz, Pascal A1 - Février, Loïc A1 - Grgurina, Nataša A1 - Weise, Martin A1 - Bellettini, Carlo A1 - Lonati, Violetta A1 - Malchiodi, Dario A1 - Monga, Mattia A1 - Morpurgo, Anna A1 - Torelli, Mauro A1 - Planteu, Lukas A1 - Standl, Bernhard A1 - Grossmann, Wilfried A1 - Neuwirth, Erich A1 - Benacka, Jan A1 - Ragonis, Noa A1 - Hodges, Steve A1 - Berry, Carol A1 - Kusterer, Peter ED - Diethelm, Ira ED - Arndt, Jannik ED - Dünnebier, Malte ED - Syrbe, Jörn T1 - Informatics in schools : local proceedings of the 6th International Conference ISSEP 2013 ; selected papers ; Oldenburg, Germany, February 26–March 2, 2013 N2 - The International Conference on Informatics in Schools: Situation, Evolution and Perspectives – ISSEP – is a forum for researchers and practitioners in the area of Informatics education, both in primary and secondary schools. It provides an opportunity for educators to reflect upon the goals and objectives of this subject, its curricula and various teaching/learning paradigms and topics, possible connections to everyday life and various ways of establishing Informatics Education in schools. This conference also cares about teaching/learning materials, various forms of assessment, traditional and innovative educational research designs, Informatics’ contribution to the preparation of children for the 21st century, motivating competitions, projects and activities supporting informatics education in school. T3 - Commentarii informaticae didacticae (CID) - 6 KW - ISSEP KW - Informatics Education Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-63688 SN - 978-3-86956-222-3 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Bahrke, Sven A1 - Einarsson, Jon M. A1 - Gislason, Johannes A1 - Haebel, Sophie A1 - Letzel, Matthias C. A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Sequence analysis of chitooligosaccharides by matrix-assisted laser desorption ionization postsource decay mass spectrometry N2 - Oligosaccharides composed of 2-acetamido-2-deoxy-D-glucopyranose (GlcNAc) and/or 2-amino-2-deoxy-D- glucopyranose (GlcN) were prepd. by chem. degrdn. of chitin or chitosan and sepd. by gel permeation chromatog. Oligosaccharides obtained after enzymic hydrolysis of chitosan [FA 0.19] with a fungal chitinase were derivatized by reductive amination with 2-aminoacridone and sequenced by matrix-assisted laser desorption ionization time-of-flight postsource decay (PSD) mass spectrometry (MS). The sequence of a trimer, D1A2, was established as D-A-A. The compn. of a hexamer D3A3 was .apprx.65% D-A-D-D-A-A and 35% D-D-A-D-A-A. The PSD MS of a nonamer D5A4-amac revealed four isobaric species D-X-Y-D-X-Y-D-A-A, where A is GlcNAc, D is GlcN, and X and Y (X ¹ Y) are mutually either D or A. This structure motif was also obsd. in a dodecamer D7A5 which was composed of eight isobaric sequences of the general formula (D-X-Y)3- D-A-A. Y1 - 2002 ER - TY - JOUR A1 - Letzel, Matthias C. A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Mass spectrometry of chitin and chitosan oligosaccharides Y1 - 2001 ER - TY - JOUR A1 - Letzel, Matthias C. A1 - Synstad, Bjoenar A1 - Eijsink, Vincent G. H. A1 - Peter-Katalinic, Jasna A1 - Peter, Martin G. T1 - Libraries of chito-oligosaccharides of mixed acetylation patterns and their interactions with chitinases Y1 - 1999 SN - 3-9806494-5-8 ER - TY - JOUR A1 - Juma, Wanyama P. A1 - Akala, Hoseah M. A1 - Eyase, Fredrick L. A1 - Muiva, Lois M. A1 - Heydenreich, Matthias A1 - Okalebo, Faith A. A1 - Gitu, Peter M. A1 - Peter, Martin G. A1 - Walsh, Douglas S. A1 - Imbuga, Mabel A1 - Yenesew, Abiy T1 - Terpurinflavone an antiplasmodial flavone from the stem of Tephrosia Purpurea JF - Phytochemistry letters N2 - The stem extract of Tephrosia purpurea showed antiplasmodial activity against the D6 (chloroquine-sensitive) and W2 (chloroquine-resistant) strains of Plasmodium falciparum with IC(50) values of 10.47 +/- 2.22 mu g/ml and 12.06 +/- 2.54 mu g/ml, respectively. A new prenylated flavone, named terpurinflavone, along with the known compounds lanceolatin A, (-)-semiglabrin and lanceolatin B have been isolated from this extract. The new compound, terpurinflavone, showed the highest antiplasmodial activity with IC(50) values of 3.12 +/- 0.28 mu M (D6) and 6.26 +/- 2.66 mu M (W2). The structures were determined on the basis of spectroscopic evidence. KW - Tephrosia purpurea KW - Leguminosae KW - Stem KW - Flavone KW - Terpurinflavone KW - Antiplasmodial Y1 - 2011 U6 - https://doi.org/10.1016/j.phytol.2011.02.010 SN - 1874-3900 VL - 4 IS - 2 SP - 176 EP - 178 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Andayi, Andrew W. A1 - Yenesew, Abiy A1 - Derese, Solomon A1 - Midiwo, Jacob O. A1 - Gitu, Peter M. A1 - Jondiko, Ogoche J. I. A1 - Akala, Hoseah M. A1 - Liyala, Pamela A1 - Wangui, Julia A1 - Waters, Norman C. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - Antiplasmodial flavonoids from Erythrina sacleuxii N2 - The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the acetone extract of the root bark afforded a new isoflavone, 7-hydroxy-4 -methoxy-3'- prenylisoflavone (trivial name 5-deoxy-3' - prenylbiochanin A) along with known isoflavonoids as the antiplasmodial principles. Flavonoids and isoflavonoids isolated from the stem bark of E. sucleuxii were also tested and showed antiplasmodial activities. The structures were determined on the basis of spectroscopic evidence Y1 - 2006 UR - http://www.thieme-connect.com/ejournals/toc/plantamedica U6 - https://doi.org/10.1055/s-2005-873200 SN - 0032-0943 ER - TY - JOUR A1 - Yildirim, Cengiz A1 - Schildgen, Taylor F. A1 - Echtler, Helmut Peter A1 - Melnick, Daniel A1 - Bookhagen, Bodo A1 - Ciner, T. Attila A1 - Niedermann, Samuel A1 - Merchel, Silke A1 - Martschini, Martin A1 - Steier, Peter A1 - Strecker, Manfred T1 - Tectonic implications of fluvial incision and pediment deformation at the northern margin of the Central Anatolian Plateau based on multiple cosmogenic nuclides JF - Tectonics N2 - We document Quaternary fluvial incision driven by fault-controlled surface deformation in the inverted intermontane Gökirmak Basin in the Central Pontide mountains along the northern margin of the Central Anatolian Plateau. In-situ-produced Be-10, Ne-21, and Cl-36 concentrations from gravel-covered fluvial terraces and pediment surfaces along the trunk stream of the basin (the Gökirmak River) yield model exposure ages ranging from 71ka to 34645ka and average fluvial incision rates over the past similar to 350ka of 0.280.01mm a(-1). Similarities between river incision rates and coastal uplift rates at the Black Sea coast suggest that regional uplift is responsible for the river incision. Model exposure ages of deformed pediment surfaces along tributaries of the trunk stream range from 605ka to 110 +/- 10ka, demonstrating that the thrust faults responsible for pediment deformation were active after those times and were likely active earlier as well as explaining the topographic relief of the region. Together, our data demonstrate cumulative incision that is linked to active internal shortening and uplift of similar to 0.3mm a(-1) in the Central Pontide orogenic wedge, which may ultimately contribute to the lateral growth of the northern Anatolian Plateau. KW - Tectonic Geomorphology KW - Fluvial Incision KW - Surface Exposure Age KW - Uplift Rate Y1 - 2013 U6 - https://doi.org/10.1002/tect.20066 SN - 0278-7407 SN - 1944-9194 VL - 32 IS - 5 SP - 1107 EP - 1120 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Gläser, Stefanie P. A1 - Bolte, Kathrin A1 - Martin, Karin A1 - Busse, Hans-Jürgen A1 - Grossart, Hans-Peter A1 - Kämpfer, Peter A1 - Gläser, Jens T1 - Novosphingobium fuchskuhlense sp nov., isolated from the north-east basin of Lake Grosse Fuchskuhle JF - International journal of systematic and evolutionary microbiology N2 - A yellow pigmented, Gram-negative, rod-shaped bacterium designated FNE08-7(T) was isolated from subsurface water of the north-east basin of the bog lake Grosse Fuchskuhle (Brandenburg, Germany). A first analysis of the nearly full-length 16S rRNA gene sequence analysis including environmental 16S rRNA gene sequences derived from freshwater ecosystems showed that strain FNE08-7(T) is the first cultured representative, to our knowledge, of the freshwater tribe Novo-A2. Further analysis indicates highest 16S rRNA gene sequence similarities to the type strains of Novosphingobium stygium (98.0%) and Novosphingobium taihuense (97.4%) and between 94.0% and 96.9% sequence similarity to other members of the genus Novosphingobium. Reconstruction of phylogenetic trees showed that strain FNE08-7(T) formed a distinct cluster with the type strains of N. stygium and N. taihuense supported by high bootstrap values. DNA DNA hybridization of strain FNE08-7(T) with N. stygium SMCC B0712(T) and N. taihuense DSM 17507(T) revealed low similarity values of 18.4% (reciprocal: 11.4%) and 23.1% (reciprocal: 54.2%), respectively. The predominant fatty acid of the isolate is C-18:1 omega 7c (56.4%) and two characteristic 2-hydroxy fatty acids, C-14:0 2-OH (16.5%) and C-15:0 2-OH (3.3%) occur. Ubiquinone Q-10 is the major respiratory quinone. The predominant polar lipids are phosphatidylethanolamine, phosphatidylmethylethanolamine, phosphatidylglycerol, sphingoglycolipid, phosphatidylcholine and minor amounts of diphosphatidylglycerol. Spermidine is the predominant polyamine. Characterization by genotypic, chemotaxonomic and phenotypic analysis indicate that strain FNE08-7(T) represents a novel species of the genus Novosphingobium within the Alphaproteobacteria. Therefore, we propose the species Novosphingobium fuchskuhlense sp. nov., with FNE08-7(T) (=DSM 25065(T)=CCM 7978(T)=CCUG 61508(T)) as the type strain. Y1 - 2013 U6 - https://doi.org/10.1099/ijs.0.043083-0 SN - 1466-5026 VL - 63 SP - 586 EP - 592 PB - Society for General Microbiology CY - Reading ER - TY - JOUR A1 - Schellenberg, Johannes A1 - Reichert, Jessica A1 - Hardt, Martin A1 - Klingelhöfer, Ines A1 - Morlock, Gertrud A1 - Schubert, Patrick A1 - Bižić, Mina A1 - Grossart, Hans-Peter A1 - Kämpfer, Peter A1 - Wilke, Thomas A1 - Glaeser, Stefanie P. T1 - The bacterial microbiome of the long-term aquarium cultured high-microbial abundance sponge Haliclona cnidata BT - sustained bioactivity despite community shifts under detrimental conditions JF - Frontiers in Marine Science N2 - Marine sponges host highly diverse but specific bacterial communities that provide essential functions for the sponge holobiont, including antimicrobial defense. Here, we characterized the bacterial microbiome of the marine sponge Haliclona cnidata that has been in culture in an artificial marine aquarium system. We tested the hypotheses (1) that the long-term aquarium cultured sponge H. cnidata is tightly associated with a typical sponge bacterial microbiota and (2) that the symbiotic Bacteria sustain bioactivity under harmful environmental conditions to facilitate holobiont survival by preventing pathogen invasion. Microscopic and phylogenetic analyses of the bacterial microbiota revealed that H. cnidata represents a high microbial abundance (HMA) sponge with a temporally stable bacterial community that significantly shifts with changing aquarium conditions. A 4-week incubation experiment was performed in small closed aquarium systems with antibiotic and/or light exclusion treatments to reduce the total bacterial and photosynthetically active sponge-associated microbiota to a treatment-specific resilient community. While the holobiont was severely affected by the experimental treatment (i.e., bleaching of the sponge, reduced bacterial abundance, shifted bacterial community composition), the biological defense and bacterial community interactions (i.e., quorum sensing activity) remained intact. 16S rRNA gene amplicon sequencing revealed a resilient community of 105 bacterial taxa, which remained in the treated sponges. These 105 taxa accounted for a relative abundance of 72-83% of the bacterial sponge microbiota of non-treated sponge fragments that have been cultured under the same conditions. We conclude that a sponge-specific resilient community stays biologically active under harmful environmental conditions, facilitating the resilience of the holobiont. In H. cnidata, bacteria are located in bacteriocytes, which may have contributed to the observed phenomenon. KW - HMA sponge KW - bacterial symbionts KW - holobiont KW - antimicrobial defense KW - quorum sensing KW - bacteriocytes Y1 - 2020 U6 - https://doi.org/10.3389/fmars.2020.00266 SN - 2296-7745 VL - 7 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Schulze-Makuch, Dirk A1 - Wagner, Dirk A1 - Kounaves, Samuel P. A1 - Mangelsdorf, Kai A1 - Devine, Kevin G. A1 - de Vera, Jean-Pierre A1 - Schmitt-Kopplin, Philippe A1 - Grossart, Hans-Peter A1 - Parro, Victor A1 - Kaupenjohann, Martin A1 - Galy, Albert A1 - Schneider, Beate A1 - Airo, Alessandro A1 - Froesler, Jan A1 - Davila, Alfonso F. A1 - Arens, Felix L. A1 - Caceres, Luis A1 - Cornejo, Francisco Solis A1 - Carrizo, Daniel A1 - Dartnell, Lewis A1 - DiRuggiero, Jocelyne A1 - Flury, Markus A1 - Ganzert, Lars A1 - Gessner, Mark O. A1 - Grathwohl, Peter A1 - Guan, Lisa A1 - Heinz, Jacob A1 - Hess, Matthias A1 - Keppler, Frank A1 - Maus, Deborah A1 - McKay, Christopher P. A1 - Meckenstock, Rainer U. A1 - Montgomery, Wren A1 - Oberlin, Elizabeth A. A1 - Probst, Alexander J. A1 - Saenz, Johan S. A1 - Sattler, Tobias A1 - Schirmack, Janosch A1 - Sephton, Mark A. A1 - Schloter, Michael A1 - Uhl, Jenny A1 - Valenzuela, Bernardita A1 - Vestergaard, Gisle A1 - Woermer, Lars A1 - Zamorano, Pedro T1 - Transitory microbial habitat in the hyperarid Atacama Desert JF - Proceedings of the National Academy of Sciences of the United States of America KW - habitat KW - aridity KW - microbial activity KW - biomarker KW - Mars Y1 - 2018 U6 - https://doi.org/10.1073/pnas.1714341115 SN - 0027-8424 VL - 115 IS - 11 SP - 2670 EP - 2675 PB - National Acad. of Sciences CY - Washington ER - TY - JOUR A1 - Giesers, Benjamin David A1 - Kamann, Sebastian A1 - Dreizler, Stefan A1 - Husser, Tim-Oliver A1 - Askar, Abbas A1 - Göttgens, Fabian A1 - Brinchmann, Jarle A1 - Latour, Marilyn A1 - Weilbacher, Peter Michael A1 - Wendt, Martin A1 - Roth, Martin M. T1 - A stellar census in globular clusters with MUSE: Binaries in NGC 3201 JF - Astronomy and astrophysics : an international weekly journal N2 - We utilise multi-epoch MUSE spectroscopy to study binary stars in the core of the Galactic globular cluster NGC 3201. Our sample consists of 3553 stars with 54 883 spectra in total comprising 3200 main-sequence stars up to 4 magnitudes below the turn-off. Each star in our sample has between 3 and 63 (with a median of 14) reliable radial velocity measurements within five years of observations. We introduce a statistical method to determine the probability of a star showing radial velocity variations based on the whole inhomogeneous radial velocity sample. Using HST photometry and an advanced dynamical MOCCA simulation of this specific cluster we overcome observational biases that previous spectroscopic studies had to deal with. This allows us to infer a binary frequency in the MUSE field of view and enables us to deduce the underlying true binary frequency of (6.75 +/- 0.72)% in NGC 3201. The comparison of the MUSE observations with the MOCCA simulation suggests a large portion of primordial binaries. We can also confirm a radial increase in the binary fraction towards the cluster centre due to mass segregation. We discovered that in the core of NGC 3201 at least (57.5 +/- 7.9)% of blue straggler stars are in a binary system. For the first time in a study of globular clusters, we were able to fit Keplerian orbits to a significant sample of 95 binaries. We present the binary system properties of eleven blue straggler stars and the connection to SX Phoenicis-type stars. We show evidence that two blue straggler formation scenarios, the mass transfer in binary (or triple) star systems and the coalescence due to binary-binary interactions, are present in our data. We also describe the binary and spectroscopic properties of four sub-subgiant (or red straggler) stars. Furthermore, we discovered two new black hole candidates with minimum masses (M sin i) of (7.68 +/- 0.50)M-circle dot, (4.4 +/- 2.8)M-circle dot, and refine the minimum mass estimate on the already published black hole to (4.53 +/- 0.21)M-circle dot, These black holes are consistent with an extensive black hole subsystem hosted by NGC 3201. KW - binaries: general KW - blue stragglers KW - stars: black holes KW - techniques: radial velocities KW - techniques: imaging spectroscopy KW - globular clusters: individual: NGC 3201 Y1 - 2019 U6 - https://doi.org/10.1051/0004-6361/201936203 SN - 0004-6361 SN - 1432-0746 VL - 632 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Göttgens, Fabian A1 - Weilbacher, Peter Michael A1 - Roth, Martin M. A1 - Dreizler, Stefan A1 - Giesers, Benjamin A1 - Husser, Tim-Oliver A1 - Kamann, Sebastian A1 - Brinchmann, Jarle A1 - Kollatschny, Wolfram A1 - Monreal-Ibero, Ana A1 - Schmidt, Kasper Borello A1 - Wendt, Martin A1 - Wisotzki, Lutz A1 - Bacon, Roland T1 - Discovery of an old nova remnant in the Galactic globular cluster M 22 JF - Astronomy and astrophysics : an international weekly journal N2 - A nova is a cataclysmic event on the surface of a white dwarf in a binary system that increases the overall brightness by several orders of magnitude. Although binary systems with a white dwarf are expected to be overabundant in globular clusters compared with in the Galaxy, only two novae from Galactic globular clusters have been observed. We present the discovery of an emission nebula in the Galactic globular cluster M 22 (NGC 6656) in observations made with the integral-field spectrograph MUSE. We extracted the spectrum of the nebula and used the radial velocity determined from the emission lines to confirm that the nebula is part of NGC 6656. Emission-line ratios were used to determine the electron temperature and density. It is estimated to have a mass of 1-17 x 10(-5) M-circle dot. This mass and the emission-line ratios indicate that the nebula is a nova remnant. Its position coincides with the reported location of a "guest star", an ancient Chinese term for transients, observed in May 48 BCE. With this discovery, this nova may be one of the oldest confirmed extra-solar events recorded in human history. KW - globular clusters: individual: NGC 6656 KW - novae, cataclysmic variables KW - techniques: imaging spectroscopy Y1 - 2019 U6 - https://doi.org/10.1051/0004-6361/201935221 SN - 1432-0746 VL - 626 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Kamann, Sebastian A1 - Husser, T. -O. A1 - Dreizler, S. A1 - Emsellem, E. A1 - Weilbacher, Peter Michael A1 - Martens, S. A1 - Bacon, R. A1 - den Brok, M. A1 - Giesers, B. A1 - Krajnovic, Davor A1 - Roth, Martin M. A1 - Wendt, Martin A1 - Wisotzki, Lutz T1 - A stellar census in globular clusters with MUSE BT - the contribution of rotation to cluster dynamics studied with 200 000 stars JF - Monthly notices of the Royal Astronomical Society N2 - This is the first of a series of papers presenting the results from our survey of 25 Galactic globular clusters with the MUSE integral-field spectrograph. In combination with our dedicated algorithm for source deblending, MUSE provides unique multiplex capabilities in crowded stellar fields and allows us to acquire samples of up to 20 000 stars within the half-light radius of each cluster. The present paper focuses on the analysis of the internal dynamics of 22 out of the 25 clusters, using about 500 000 spectra of 200 000 individual stars. Thanks to the large stellar samples per cluster, we are able to perform a detailed analysis of the central rotation and dispersion fields using both radial profiles and two-dimensional maps. The velocity dispersion profiles we derive show a good general agreement with existing radial velocity studies but typically reach closer to the cluster centres. By comparison with proper motion data, we derive or update the dynamical distance estimates to 14 clusters. Compared to previous dynamical distance estimates for 47 Tuc, our value is in much better agreement with other methods. We further find significant (>3 sigma) rotation in the majority (13/22) of our clusters. Our analysis seems to confirm earlier findings of a link between rotation and the ellipticities of globular clusters. In addition, we find a correlation between the strengths of internal rotation and the relaxation times of the clusters, suggesting that the central rotation fields are relics of the cluster formation that are gradually dissipated via two-body relaxation. KW - techniques: imaging spectroscopy KW - stars: kinematics and dynamics KW - globular clusters: general Y1 - 2017 U6 - https://doi.org/10.1093/mnras/stx2719 SN - 0035-8711 SN - 1365-2966 VL - 473 IS - 4 SP - 5591 EP - 5616 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Göttgens, Fabian A1 - Husser, Tim-Oliver A1 - Kamann, Sebastian A1 - Dreizler, Stefan A1 - Giesers, Benjamin A1 - Kollatschny, Wolfram A1 - Weilbacher, Peter Michael A1 - Roth, Martin M. A1 - Wendt, Martin T1 - A stellar census in globular clusters with MUSE: A spectral catalogue of emission-line sources JF - Astronomy and astrophysics : an international weekly journal N2 - Aims. Globular clusters produce many exotic stars due to a much higher frequency of dynamical interactions in their dense stellar environments. Some of these objects were observed together with several hundred thousand other stars in our MUSE survey of 26 Galactic globular clusters. Assuming that at least a few exotic stars have exotic spectra (i.e. spectra that contain emission lines), we can use this large spectroscopic data set of over a million stellar spectra as a blind survey to detect stellar exotica in globular clusters. Methods. To detect emission lines in each spectrum, we modelled the expected shape of an emission line as a Gaussian curve. This template was used for matched filtering on the di fferences between each observed 1D spectrum and its fitted spectral model. The spectra with the most significant detections of H alpha emission are checked visually and cross-matched with published catalogues. Results. We find 156 stars with H alpha emission, including several known cataclysmic variables (CV) and two new CVs, pulsating variable stars, eclipsing binary stars, the optical counterpart of a known black hole, several probable sub-subgiants and red stragglers, and 21 background emission-line galaxies. We find possible optical counterparts to 39 X-ray sources, as we detected H alpha emission in several spectra of stars that are close to known positions of Chandra X-ray sources. This spectral catalogue can be used to supplement existing or future X-ray or radio observations with spectra of potential optical counterparts to classify the sources. KW - globular clusters: general KW - stars: emission-line, Be KW - novae KW - cataclysmic variables KW - catalogs KW - techniques: imaging spectroscopy Y1 - 2019 U6 - https://doi.org/10.1051/0004-6361/201936485 SN - 0004-6361 SN - 1432-0746 VL - 631 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Aarts, Alexander A. A1 - Anderson, Joanna E. A1 - Anderson, Christopher J. A1 - Attridge, Peter R. A1 - Attwood, Angela A1 - Axt, Jordan A1 - Babel, Molly A1 - Bahnik, Stepan A1 - Baranski, Erica A1 - Barnett-Cowan, Michael A1 - Bartmess, Elizabeth A1 - Beer, Jennifer A1 - Bell, Raoul A1 - Bentley, Heather A1 - Beyan, Leah A1 - Binion, Grace A1 - Borsboom, Denny A1 - Bosch, Annick A1 - Bosco, Frank A. A1 - Bowman, Sara D. A1 - Brandt, Mark J. A1 - Braswell, Erin A1 - Brohmer, Hilmar A1 - Brown, Benjamin T. A1 - Brown, Kristina A1 - Bruening, Jovita A1 - Calhoun-Sauls, Ann A1 - Callahan, Shannon P. A1 - Chagnon, Elizabeth A1 - Chandler, Jesse A1 - Chartier, Christopher R. A1 - Cheung, Felix A1 - Christopherson, Cody D. A1 - Cillessen, Linda A1 - Clay, Russ A1 - Cleary, Hayley A1 - Cloud, Mark D. A1 - Cohn, Michael A1 - Cohoon, Johanna A1 - Columbus, Simon A1 - Cordes, Andreas A1 - Costantini, Giulio A1 - Alvarez, Leslie D. Cramblet A1 - Cremata, Ed A1 - Crusius, Jan A1 - DeCoster, Jamie A1 - DeGaetano, Michelle A. A1 - Della Penna, Nicolas A1 - den Bezemer, Bobby A1 - Deserno, Marie K. A1 - Devitt, Olivia A1 - Dewitte, Laura A1 - Dobolyi, David G. A1 - Dodson, Geneva T. A1 - Donnellan, M. Brent A1 - Donohue, Ryan A1 - Dore, Rebecca A. A1 - Dorrough, Angela A1 - Dreber, Anna A1 - Dugas, Michelle A1 - Dunn, Elizabeth W. A1 - Easey, Kayleigh A1 - Eboigbe, Sylvia A1 - Eggleston, Casey A1 - Embley, Jo A1 - Epskamp, Sacha A1 - Errington, Timothy M. A1 - Estel, Vivien A1 - Farach, Frank J. A1 - Feather, Jenelle A1 - Fedor, Anna A1 - Fernandez-Castilla, Belen A1 - Fiedler, Susann A1 - Field, James G. A1 - Fitneva, Stanka A. A1 - Flagan, Taru A1 - Forest, Amanda L. A1 - Forsell, Eskil A1 - Foster, Joshua D. A1 - Frank, Michael C. A1 - Frazier, Rebecca S. A1 - Fuchs, Heather A1 - Gable, Philip A1 - Galak, Jeff A1 - Galliani, Elisa Maria A1 - Gampa, Anup A1 - Garcia, Sara A1 - Gazarian, Douglas A1 - Gilbert, Elizabeth A1 - Giner-Sorolla, Roger A1 - Glöckner, Andreas A1 - Göllner, Lars A1 - Goh, Jin X. A1 - Goldberg, Rebecca A1 - Goodbourn, Patrick T. A1 - Gordon-McKeon, Shauna A1 - Gorges, Bryan A1 - Gorges, Jessie A1 - Goss, Justin A1 - Graham, Jesse A1 - Grange, James A. A1 - Gray, Jeremy A1 - Hartgerink, Chris A1 - Hartshorne, Joshua A1 - Hasselman, Fred A1 - Hayes, Timothy A1 - Heikensten, Emma A1 - Henninger, Felix A1 - Hodsoll, John A1 - Holubar, Taylor A1 - Hoogendoorn, Gea A1 - Humphries, Denise J. A1 - Hung, Cathy O. -Y. A1 - Immelman, Nathali A1 - Irsik, Vanessa C. A1 - Jahn, Georg A1 - Jaekel, Frank A1 - Jekel, Marc A1 - Johannesson, Magnus A1 - Johnson, Larissa G. A1 - Johnson, David J. A1 - Johnson, Kate M. A1 - Johnston, William J. A1 - Jonas, Kai A1 - Joy-Gaba, Jennifer A. A1 - Kappes, Heather Barry A1 - Kelso, Kim A1 - Kidwell, Mallory C. A1 - Kim, Seung Kyung A1 - Kirkhart, Matthew A1 - Kleinberg, Bennett A1 - Knezevic, Goran A1 - Kolorz, Franziska Maria A1 - Kossakowski, Jolanda J. A1 - Krause, Robert Wilhelm A1 - Krijnen, Job A1 - Kuhlmann, Tim A1 - Kunkels, Yoram K. A1 - Kyc, Megan M. A1 - Lai, Calvin K. A1 - Laique, Aamir A1 - Lakens, Daniel A1 - Lane, Kristin A. A1 - Lassetter, Bethany A1 - Lazarevic, Ljiljana B. A1 - LeBel, Etienne P. A1 - Lee, Key Jung A1 - Lee, Minha A1 - Lemm, Kristi A1 - Levitan, Carmel A. A1 - Lewis, Melissa A1 - Lin, Lin A1 - Lin, Stephanie A1 - Lippold, Matthias A1 - Loureiro, Darren A1 - Luteijn, Ilse A1 - Mackinnon, Sean A1 - Mainard, Heather N. A1 - Marigold, Denise C. A1 - Martin, Daniel P. A1 - Martinez, Tylar A1 - Masicampo, E. J. A1 - Matacotta, Josh A1 - Mathur, Maya A1 - May, Michael A1 - Mechin, Nicole A1 - Mehta, Pranjal A1 - Meixner, Johannes A1 - Melinger, Alissa A1 - Miller, Jeremy K. A1 - Miller, Mallorie A1 - Moore, Katherine A1 - Möschl, Marcus A1 - Motyl, Matt A1 - Müller, Stephanie M. A1 - Munafo, Marcus A1 - Neijenhuijs, Koen I. A1 - Nervi, Taylor A1 - Nicolas, Gandalf A1 - Nilsonne, Gustav A1 - Nosek, Brian A. A1 - Nuijten, Michele B. A1 - Olsson, Catherine A1 - Osborne, Colleen A1 - Ostkamp, Lutz A1 - Pavel, Misha A1 - Penton-Voak, Ian S. A1 - Perna, Olivia A1 - Pernet, Cyril A1 - Perugini, Marco A1 - Pipitone, R. Nathan A1 - Pitts, Michael A1 - Plessow, Franziska A1 - Prenoveau, Jason M. A1 - Rahal, Rima-Maria A1 - Ratliff, Kate A. A1 - Reinhard, David A1 - Renkewitz, Frank A1 - Ricker, Ashley A. A1 - Rigney, Anastasia A1 - Rivers, Andrew M. A1 - Roebke, Mark A1 - Rutchick, Abraham M. A1 - Ryan, Robert S. A1 - Sahin, Onur A1 - Saide, Anondah A1 - Sandstrom, Gillian M. A1 - Santos, David A1 - Saxe, Rebecca A1 - Schlegelmilch, Rene A1 - Schmidt, Kathleen A1 - Scholz, Sabine A1 - Seibel, Larissa A1 - Selterman, Dylan Faulkner A1 - Shaki, Samuel A1 - Simpson, William B. A1 - Sinclair, H. Colleen A1 - Skorinko, Jeanine L. M. A1 - Slowik, Agnieszka A1 - Snyder, Joel S. A1 - Soderberg, Courtney A1 - Sonnleitner, Carina A1 - Spencer, Nick A1 - Spies, Jeffrey R. A1 - Steegen, Sara A1 - Stieger, Stefan A1 - Strohminger, Nina A1 - Sullivan, Gavin B. A1 - Talhelm, Thomas A1 - Tapia, Megan A1 - te Dorsthorst, Anniek A1 - Thomae, Manuela A1 - Thomas, Sarah L. A1 - Tio, Pia A1 - Traets, Frits A1 - Tsang, Steve A1 - Tuerlinckx, Francis A1 - Turchan, Paul A1 - Valasek, Milan A1 - Van Aert, Robbie A1 - van Assen, Marcel A1 - van Bork, Riet A1 - van de Ven, Mathijs A1 - van den Bergh, Don A1 - van der Hulst, Marije A1 - van Dooren, Roel A1 - van Doorn, Johnny A1 - van Renswoude, Daan R. A1 - van Rijn, Hedderik A1 - Vanpaemel, Wolf A1 - Echeverria, Alejandro Vasquez A1 - Vazquez, Melissa A1 - Velez, Natalia A1 - Vermue, Marieke A1 - Verschoor, Mark A1 - Vianello, Michelangelo A1 - Voracek, Martin A1 - Vuu, Gina A1 - Wagenmakers, Eric-Jan A1 - Weerdmeester, Joanneke A1 - Welsh, Ashlee A1 - Westgate, Erin C. A1 - Wissink, Joeri A1 - Wood, Michael A1 - Woods, Andy A1 - Wright, Emily A1 - Wu, Sining A1 - Zeelenberg, Marcel A1 - Zuni, Kellylynn T1 - Estimating the reproducibility of psychological science JF - Science N2 - Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams. Y1 - 2015 U6 - https://doi.org/10.1126/science.aac4716 SN - 1095-9203 SN - 0036-8075 VL - 349 IS - 6251 PB - American Assoc. for the Advancement of Science CY - Washington ER - TY - JOUR A1 - Weilbacher, Peter Michael A1 - Monreal-Ibero, Ana A1 - Verhamme, Anne A1 - Sandin, Christer A1 - Steinmetz, Matthias A1 - Kollatschny, Wolfram A1 - Krajnovic, Davor A1 - Kamann, Sebastian A1 - Roth, Martin M. A1 - Erroz-Ferrer, Santiago A1 - Marino, Raffaella Anna A1 - Maseda, Michael V. A1 - Wendt, Martin A1 - Bacon, Roland A1 - Dreizler, Stefan A1 - Richard, Johan A1 - Wisotzki, Lutz T1 - Lyman-continuum leakage as dominant source of diffuse ionized gas in the Antennae galaxy JF - Astronomy and astrophysics : an international weekly journal N2 - The Antennae galaxy (NGC 4038/39) is the closest major interacting galaxy system and is therefore often studied as a merger prototype. We present the first comprehensive integral field spectroscopic dataset of this system, observed with the MUSE instrument at the ESO VLT. We cover the two regions in this system which exhibit recent star formation: the central galaxy interaction and a region near the tip of the southern tidal tail. In these fields, we detect H II regions and diffuse ionized gas to unprecedented depth. About 15% of the ionized gas was undetected by previous observing campaigns. This newly detected faint ionized gas is visible everywhere around the central merger, and shows filamentary structure. We estimate diffuse gas fractions of about 60% in the central field and 10% in the southern region. We are able to show that the southern region contains a significantly different population of H II regions, showing fainter luminosities. By comparing H II region luminosities with the HST catalog of young star clusters in the central field, we estimate that there is enough Lyman-continuum leakage in the merger to explain the amount of diffuse ionized gas that we detect. We compare the Lyman-continuum escape fraction of each H II region against emission line ratios that are sensitive to the ionization parameter. While we find no systematic trend between these properties, the most extreme line ratios seem to be strong indicators of density bounded ionization. Extrapolating the Lyman-continuum escape fractions to the southern region, we conclude that simply from the comparison of the young stellar populations to the ionized gas there is no need to invoke other ionization mechanisms than Lyman-continuum leaking H II regions for the diffuse ionized gas in the Antennae. KW - galaxies: interactions KW - galaxies: individual: NGC 4038, NGC 4039 KW - galaxies: ISM KW - ISM: structure KW - H II regions Y1 - 2018 U6 - https://doi.org/10.1051/0004-6361/201731669 SN - 1432-0746 VL - 611 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Krösche, Christian A1 - Crescenzi, Orlando A1 - Hoffbauer, Wilfried A1 - Jansen, Martin A1 - Napolitano, Alessandra A1 - Prota, Guiseppe A1 - Peter, Martin G. T1 - Synthesis of dopamines labelled with 13C in the alpha- or beta-side chain positions, and their application for structure studies on melanins by solid state NMR spectroscopy Y1 - 1994 ER - TY - GEN A1 - Lachmair, Martin A1 - Ruiz Fernandez, Susana A1 - Bury, Nils-Alexander A1 - Gerjets, Peter A1 - Fischer, Martin H. A1 - Bock, Otmar L. T1 - How body orientation affects concepts of space, time and valence BT - functional relevance of integrating sensorimotor experiences during word processing T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - The aim of the present study was to test the functional relevance of the spatial concepts UP or DOWN for words that use these concepts either literally (space) or metaphorically (time, valence). A functional relevance would imply a symmetrical relationship between the spatial concepts and words related to these concepts, showing that processing words activate the related spatial concepts on one hand, but also that an activation of the concepts will ease the retrieval of a related word on the other. For the latter, the rotation angle of participant's body position was manipulated either to an upright or a head-down tilted body position to activate the related spatial concept. Afterwards participants produced in a within-subject design previously memorized words of the concepts space, time and valence according to the pace of a metronome. All words were related either to the spatial concept UP or DOWN. The results including Bayesian analyses show (1) a significant interaction between body position and words using the concepts UP and DOWN literally, (2) a marginal significant interaction between body position and temporal words and (3) no effect between body position and valence words. However, post-hoc analyses suggest no difference between experiments. Thus, the authors concluded that integrating sensorimotor experiences is indeed of functional relevance for all three concepts of space, time and valence. However, the strength of this functional relevance depends on how close words are linked to mental concepts representing vertical space. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 505 KW - mental timeline KW - cognition KW - language KW - representation KW - hypothesis KW - mechanisms KW - future KW - flies KW - line KW - mind Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-410942 SN - 1866-8364 IS - 505 ER - TY - JOUR A1 - Soliveres, Santiago A1 - van der Plas, Fons A1 - Manning, Peter A1 - Prati, Daniel A1 - Gossner, Martin M. A1 - Renner, Swen C. A1 - Alt, Fabian A1 - Arndt, Hartmut A1 - Baumgartner, Vanessa A1 - Binkenstein, Julia A1 - Birkhofer, Klaus A1 - Blaser, Stefan A1 - Blüthgen, Nico A1 - Boch, Steffen A1 - Böhm, Stefan A1 - Börschig, Carmen A1 - Buscot, Francois A1 - Diekötter, Tim A1 - Heinze, Johannes A1 - Hölzel, Norbert A1 - Jung, Kirsten A1 - Klaus, Valentin H. A1 - Kleinebecker, Till A1 - Klemmer, Sandra A1 - Krauss, Jochen A1 - Lange, Markus A1 - Morris, E. Kathryn A1 - Müller, Jörg A1 - Oelmann, Yvonne A1 - Overmann, Jörg A1 - Pasalic, Esther A1 - Rillig, Matthias C. A1 - Schaefer, H. Martin A1 - Schloter, Michael A1 - Schmitt, Barbara A1 - Schöning, Ingo A1 - Schrumpf, Marion A1 - Sikorski, Johannes A1 - Socher, Stephanie A. A1 - Solly, Emily F. A1 - Sonnemann, Ilja A1 - Sorkau, Elisabeth A1 - Steckel, Juliane A1 - Steffan-Dewenter, Ingolf A1 - Stempfhuber, Barbara A1 - Tschapka, Marco A1 - Türke, Manfred A1 - Venter, Paul C. A1 - Weiner, Christiane N. A1 - Weisser, Wolfgang W. A1 - Werner, Michael A1 - Westphal, Catrin A1 - Wilcke, Wolfgang A1 - Wolters, Volkmar A1 - Wubet, Tesfaye A1 - Wurst, Susanne A1 - Fischer, Markus A1 - Allan, Eric T1 - Biodiversity at multiple trophic levels is needed for ecosystem multifunctionality JF - Nature : the international weekly journal of science Y1 - 2016 U6 - https://doi.org/10.1038/nature19092 SN - 0028-0836 SN - 1476-4687 VL - 536 SP - 456 EP - + PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Lachmair, Martin A1 - Fernandez, Susana Ruiz A1 - Bury, Nils-Alexander A1 - Gerjets, Peter A1 - Fischer, Martin H. A1 - Bock, Otmar L. T1 - How Body Orientation Affects Concepts of Space, Time and Valence: Functional Relevance of Integrating Sensorimotor Experiences during Word Processing JF - PLoS one Y1 - 2016 U6 - https://doi.org/10.1371/journal.pone.0165795 SN - 1932-6203 VL - 11 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Husser, Tim-Oliver A1 - Kamann, Sebastian A1 - Dreizler, Stefan A1 - Wendt, Martin A1 - Wulff, Nina A1 - Bacon, Roland A1 - Wisotzki, Lutz A1 - Brinchmann, Jarle A1 - Weilbacher, Peter Michael A1 - Roth, Martin M. A1 - Monreal-Ibero, Ana T1 - MUSE crowded field 3D spectroscopy of over 12 000 stars in the globular cluster NGC 6397 I. The first comprehensive HRD of a globular cluster JF - Nucleic acids research N2 - Aims. We demonstrate the high multiplex advantage of crowded field 3D spectroscopy with the new integral field spectrograph MUSE by means of a spectroscopic analysis of more than 12 000 individual stars in the globular cluster NGC 6397. Methods. The stars are deblended with a point spread function fitting technique, using a photometric reference catalogue from HST as prior, including relative positions and brightnesses. This catalogue is also used for a first analysis of the extracted spectra, followed by an automatic in-depth analysis via a full-spectrum fitting method based on a large grid of PHOENIX spectra. Results. We analysed the largest sample so far available for a single globular cluster of 18 932 spectra from 12 307 stars in NGC 6397. We derived a mean radial velocity of v(rad) = 17.84 +/- 0.07 km s(-1) and a mean metallicity of [Fe/H] = -2.120 +/- 0.002, with the latter seemingly varying with temperature for stars on the red giant branch (RGB). We determine Teff and [Fe/H] from the spectra, and log g from HST photometry. This is the first very comprehensive Hertzsprung-Russell diagram (HRD) for a globular cluster based on the analysis of several thousands of stellar spectra, ranging from the main sequence to the tip of the RGB. Furthermore, two interesting objects were identified; one is a post-AGB star and the other is a possible millisecond-pulsar companion. KW - methods: data analysis KW - techniques: imaging spectroscopy KW - planets and satellites: fundamental parameters KW - stars: atmospheres KW - pulsars: general KW - globular clusters: individual: NGC 6397 Y1 - 2016 U6 - https://doi.org/10.1051/0004-6361/201526949 SN - 1432-0746 VL - 588 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Herder, Martin A1 - Utecht, Manuel Martin A1 - Manicke, Nicole A1 - Grubert, Lutz A1 - Pätzel, Michael A1 - Saalfrank, Peter A1 - Hecht, Stefan T1 - Switching with orthogonal stimuli electrochemical ring-closure and photochemical ring-opening of bis(thiazolyl) maleimides JF - Chemical science N2 - The photochemistry as well as electrochemistry of novel donor-acceptor bis(morpholinothiazolyl)maleimides has been investigated. Proper substitution of these diarylethene-type molecular switches leads to the unique situation in which their ring-closure can only be accomplished electrochemically, while ring-opening can only be achieved photochemically. Hence, these switches operate with orthogonal stimuli, i.e. redox potential and light, respectively. The switch system could be optimized by introducing trifluoromethyl groups at the reactive carbon atoms in order to avoid by-product formation during oxidative ring closure. Both photochemical and electrochemical pathways were investigated for methylated, trifluoromethylated, and nonsymmetrical bis(morpholinothiazolyl) maleimides as well as the bis(morpholinothiazolyl) cyclopentene reference compound. With the aid of the nonsymmetrical "mixed" derivative, the mechanism of electrochemically driven ring closure could be elucidated and seems to proceed via a dicationic intermediate generated by two-fold oxidation. All experimental work has been complemented by density functional theory that provides detailed insights into the thermodynamics of the ring-open and closed forms, the nature of their excited states, and the reactivity of their neutral as well as ionized species in different electronic configurations. The particular diarylethene systems described herein could serve in multifunctional (logic) devices operated by different stimuli (inputs) and may pave the way to converting light into electrical energy via photoinduced "pumping" of redox-active meta-stable states. Y1 - 2013 U6 - https://doi.org/10.1039/c2sc21681g SN - 2041-6520 VL - 4 IS - 3 SP - 1028 EP - 1040 PB - Royal Society of Chemistry CY - Cambridge ER - TY - GEN A1 - Schulze, Michael A1 - Utecht, Manuel Martin A1 - Moldt, Thomas A1 - Przyrembel, Daniel A1 - Gahl, Cornelius A1 - Weinelt, Martin A1 - Saalfrank, Peter A1 - Tegeder, Petra T1 - Nonlinear optical response of photochromic azobenzene-functionalized self-assembled monolayers N2 - The combination of photochromic and nonlinear optical (NLO) properties of azobenzene-functionalized self-assembled monolayers (SAMs) constitutes an intriguing step towards novel photonic and optoelectronic devices. By utilizing the second-order NLO process of second harmonic generation (SHG), supported by density-functional theory and correlated wave function method calculations, we demonstrate that the photochromic interface provides the necessary prerequisites en route towards possible future technical applications: we find a high NLO contrast on the order of 16% between the switching states. These are furthermore accessible reversibly and with high efficiencies in terms of cross sections on the order of 10−18 cm2 for both photoisomerization reactions, i.e., drivable by means of low-power LED light sources. Finally, both photostationary states (PSSs) are thermally stable at ambient conditions. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 196 Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-81198 ER - TY - JOUR A1 - Luo, Ying A1 - Utecht, Manuel Martin A1 - Dokic, Jadranka A1 - Korchak, Sergey A1 - Vieth, Hans-Martin A1 - Haag, Rainer A1 - Saalfrank, Peter T1 - Cis-trans isomerisation of substituted aromatic imines a comparative experimental and theoretical study JF - ChemPhysChem : a European journal of chemical physics and physical chemistry N2 - The cis-trans isomerisation of N-benzylideneaniline (NBA) and derivatives containing a central C=N bond has been investigated experimentally and theoretically. Eight different NBA molecules in three different solvents were irradiated to enforce a photochemical trans (hv) -> cis isomerisation and the kinetics of the thermal backreaction cis (Delta)-> trans were determined by NMR spectroscopy measurements in the temperature range between 193 and 288 K. Theoretical calculations using density functional theory and Eyring transition-state theory were carried out for 12 different NBA species in the gas phase and three different solvents to compute thermal isomerisation rates of the thermal back reaction. While the computed absolute rates are too large, they reveal and explain experimental trends. Time-dependent density functional theory provides optical spectra for vertical transitions and excitation energy differences between trans and cis forms. Together with isomerisation rates, the latter can be used to identify "optimal switches" with good photochromicity and reasonable thermal stability. KW - density functional calculations KW - imines KW - isomerization KW - photochemistry KW - thermochemistry Y1 - 2011 U6 - https://doi.org/10.1002/cphc.201100179 SN - 1439-4235 VL - 12 IS - 12 SP - 2311 EP - 2321 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Schulze, Michael A1 - Utecht, Manuel Martin A1 - Moldt, Thomas A1 - Przyrembel, Daniel A1 - Gahl, Cornelius A1 - Weinelt, Martin A1 - Saalfrank, Peter A1 - Tegeder, Petra T1 - Nonlinear optical response of photochromic azobenzene-functionalized self-assembled monolayers JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - The combination of photochromic and nonlinear optical (NLO) properties of azobenzene-functionalized self-assembled monolayers (SAMs) constitutes an intriguing step towards novel photonic and optoelectronic devices. By utilizing the second-order NLO process of second harmonic generation (SHG), supported by density-functional theory and correlated wave function method calculations, we demonstrate that the photochromic interface provides the necessary prerequisites en route towards possible future technical applications: we find a high NLO contrast on the order of 16% between the switching states. These are furthermore accessible reversibly and with high efficiencies in terms of cross sections on the order of 10(-18) cm(2) for both photoisomerization reactions, i.e., drivable by means of low-power LED light sources. Finally, both photostationary states (PSSs) are thermally stable at ambient conditions. Y1 - 2015 U6 - https://doi.org/10.1039/c5cp03093e SN - 1463-9076 SN - 1463-9084 VL - 17 IS - 27 SP - 18079 EP - 18086 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Schulze, Michael A1 - Utecht, Manuel Martin A1 - Moldt, Thomas A1 - Przyrembel, Daniel A1 - Gahl, Cornelius A1 - Weinelt, Martin A1 - Saalfrank, Peter A1 - Tegeder, Petra T1 - Nonlinear optical response of photochromic azobenzene-functionalized self-assembled monolayers JF - Physical chemistry, chemical physics : PCCP ; a journal of European Chemical Societies N2 - The combination of photochromic and nonlinear optical (NLO) properties of azobenzene-functionalized self-assembled monolayers (SAMs) constitutes an intriguing step towards novel photonic and optoelectronic devices. By utilizing the second-order NLO process of second harmonic generation (SHG), supported by density-functional theory and correlated wave function method calculations, we demonstrate that the photochromic interface provides the necessary prerequisites en route towards possible future technical applications: we find a high NLO contrast on the order of 16% between the switching states. These are furthermore accessible reversibly and with high efficiencies in terms of cross sections on the order of 10−18 cm2 for both photoisomerization reactions, i.e., drivable by means of low-power LED light sources. Finally, both photostationary states (PSSs) are thermally stable at ambient conditions. Y1 - 2015 U6 - https://doi.org/10.1039/c5cp03093e SN - 1463-9076 SN - 1463-9084 VL - 27 IS - 17 SP - 18079 EP - 18086 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Volk, Benno A1 - Markert, Doreen A1 - Riejok, Henriette A1 - Dittberner, Jürgen A1 - Wanka, Johanna A1 - Wilkens, Martin A1 - Görtemaker, Manfred A1 - Regierer, Babette A1 - Steup, Martin A1 - Müller-Röber, Bernd A1 - Wernicke, Matthias A1 - Altenberger, Uwe A1 - Stölting, Erhard A1 - Ferý, Carolin A1 - Egenter, Peter A1 - Lenz, Claudia A1 - Jakubowski, Zuzanna A1 - Klötzer, Sylvia A1 - Krause, Michael A1 - Dietsch, Ulrich T1 - Portal = Vor der Präsidenten-Wahl: Erwartungen, Wünsche, Vorschläge BT - Die Potsdamer Universitätszeitung N2 - Aus dem Inhalt: - Vor der Präsidenten-Wahl: Erwartungen, Wünsche, Vorschläge - Der AStA in der Krise? - Über Satire und Macht in der DDR - Vom Fünf-Sterne-Koch zum Mensaleiter T3 - Portal: Das Potsdamer Universitätsmagazin - 04-05/2006 Y1 - 2006 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-440005 SN - 1618-6893 IS - 04-05/2006 ER - TY - GEN A1 - Abramowski, Attila A1 - Aharonian, Felix A. A1 - Benkhali, Faical Ait A1 - Akhperjanian, A. G. A1 - Angüner, Ekrem Oǧuzhan A1 - Backes, Michael A1 - Balenderan, Shangkari A1 - Balzer, Arnim A1 - Barnacka, Anna A1 - Becherini, Yvonne A1 - Tjus, Julia Becker A1 - Berge, David A1 - Bernhard, Sabrina A1 - Bernlöhr, Konrad A1 - Birsin, E. A1 - Biteau, Jonathan A1 - Böttcher, Markus A1 - Boisson, Catherine A1 - Bolmont, J. A1 - Bordas, Pol A1 - Bregeon, Johan A1 - Brun, Francois A1 - Brun, Pierre A1 - Bryan, Mark A1 - Bulik, Tomasz A1 - Carrigan, Svenja A1 - Casanova, Sabrina A1 - Chadwick, Paula M. A1 - Chakraborty, Nachiketa A1 - Chalme-Calvet, R. A1 - Chaves, Ryan C. G. A1 - Chretien, M. A1 - Colafrancesco, Sergio A1 - Cologna, Gabriele A1 - Conrad, Jan A1 - Couturier, Claire A1 - Cui, Yudong A1 - Davids, Isak Delberth A1 - Degrange, Bernhard A1 - Deil, Christoph A1 - deWilt, P. A1 - Djannati-Ataï, A. A1 - Domainko, Wilfried A1 - Donath, Axel A1 - Dubus, G. A1 - Dutson, K. A1 - Dyks, J. A1 - Dyrda, M. A1 - Edwards, Tanya A1 - Egberts, Kathrin A1 - Eger, Peter A1 - Espigat, P. A1 - Farnier, C. A1 - Fegan, Stephen A1 - Feinstein, Fabrice A1 - Fernandes, Milton Virgilio A1 - Fernandez, Diane A1 - Fiasson, A. A1 - Fontaine, Gerard A1 - Förster, Andreas A1 - Fuessling, M. A1 - Gabici, S. A1 - Gajdus, M. A1 - Gallant, Yves A. A1 - Garrigoux, Tania A1 - Giavitto, G. A1 - Giebels, Berrie A1 - Glicenstein, Jean-Francois A1 - Gottschall, Daniel A1 - Grondin, M. -H. A1 - Grudzinska, M. A1 - Hadasch, Daniela A1 - Haeffner, S. A1 - Hahn, Joachim A1 - Harris, Jonathan A1 - Heinzelmann, Götz A1 - Henri, G. A1 - Hermann, German A1 - Hervet, O. A1 - Hillert, Andreas A1 - Hinton, James Anthony A1 - Hofmann, Werner A1 - Hofverberg, Petter A1 - Holler, Markus A1 - Horns, Dieter A1 - Ivascenko, Alex A1 - Jacholkowska, A. A1 - Jahn, C. A1 - Jamrozy, Marek A1 - Janiak, M. A1 - Jankowsky, F. A1 - Jung-Richardt, I. A1 - Kastendieck, Max Anton A1 - Katarzynski, K. A1 - Katz, U. A1 - Kaufmann, S. A1 - Khelifi, B. A1 - Kieffer, Michel A1 - Klepser, S. A1 - Klochkov, Dmitry A1 - Kluzniak, W. A1 - Kolitzus, David A1 - Komin, Nu A1 - Kosack, Karl A1 - Krakau, Steffen A1 - Krayzel, F. A1 - Krueger, Pat P. A1 - Laffon, H. A1 - Lamanna, G. A1 - Lefaucheur, J. A1 - Lefranc, Valentin A1 - Lemiere, A. A1 - Lemoine-Goumard, M. A1 - Lenain, J. -P. A1 - Lohse, Thomas A1 - Lopatin, A. A1 - Lu, Chia-Chun A1 - Marandon, Vincent A1 - Marcowith, Alexandre A1 - Marx, Ramin A1 - Maurin, G. A1 - Maxted, Nigel A1 - Mayer, Michael A1 - McComb, T. J. Lowry A1 - Mehault, J. A1 - Meintjes, P. J. A1 - Menzler, Ulf A1 - Meyer, M. A1 - Mitchell, Alison M. W. A1 - Moderski, R. A1 - Mohamed, M. A1 - Mora, K. A1 - Moulin, Emmanuel A1 - Murach, Thomas A1 - de Naurois, Mathieu A1 - Niemiec, J. A1 - Nolan, Sam J. A1 - Oakes, Louise A1 - Odaka, Hirokazu A1 - Ohm, S. A1 - Optiz, Björn A1 - Ostrowski, Michal A1 - Oya, I. A1 - Panter, Michael A1 - Parsons, R. Daniel A1 - Arribas, M. Paz A1 - Pekeur, Nikki W. A1 - Pelletier, G. A1 - Petrucci, P. -O. A1 - Peyaud, B. A1 - Pita, S. A1 - Poon, Helen A1 - Pühlhofer, Gerd A1 - Punch, M. A1 - Quirrenbach, A. A1 - Raab, S. A1 - Reichardt, I. A1 - Reimer, Anita A1 - Reimer, Olaf A1 - Renaud, Metz A1 - de los Reyes, Raquel A1 - Rieger, Frank A1 - Romoli, C. A1 - Rosier-Lees, S. A1 - Rowell, G. A1 - Rudak, B. A1 - Rulten, C. B. A1 - Sahakian, Vardan A1 - Salek, D. A1 - Sanchez, David M. A1 - Santangelo, Andrea A1 - Schlickeiser, Reinhard A1 - Schuessler, F. A1 - Schulz, A. A1 - Schwanke, Ullrich A1 - Schwarzburg, S. A1 - Schwemmer, S. A1 - Sol, H. A1 - Spanier, Felix A1 - Spengler, G. A1 - Spies, Franziska A1 - Stawarz, Lukasz A1 - Steenkamp, Riaan A1 - Stegmann, Christian A1 - Stinzing, F. A1 - Stycz, K. A1 - Sushch, Iurii A1 - Tavernet, J. -P. A1 - Tavernier, T. A1 - Taylor, A. M. A1 - Terrier, R. A1 - Tluczykont, Martin A1 - Trichard, C. A1 - Valerius, K. A1 - van Eldik, C. A1 - van Soelen, B. A1 - Vasileiadis, Georges A1 - Veh, J. A1 - Venter, Christo A1 - Viana, Aion A1 - Vincent, P. A1 - Vink, Jacco A1 - Völk, Heinrich J. A1 - Volpe, Francesca A1 - Vorster, Martine A1 - Vuillaume, T. A1 - Wagner, S. J. A1 - Wagner, P. A1 - Wagner, R. M. A1 - Ward, Martin A1 - Weidinger, Matthias A1 - Weitzel, Quirin A1 - White, R. A1 - Wierzcholska, A. A1 - Willmann, P. A1 - Woernlein, A. A1 - Wouters, D. A1 - Yang, Ruizhi A1 - Zabalza, Victor A1 - Zaborov, Dmitry A1 - Zacharias, M. A1 - Zdziarski, A. A. A1 - Zech, Alraune A1 - Zechlin, Hannes -S. T1 - H.E.S.S. detection of TeV emission from the interaction region between the supernova remnant G349.7+0.2 and a molecular cloud (vol 574, A100, 2015) T2 - Astronomy and astrophysics : an international weekly journal KW - gamma rays: general KW - ISM: supernova remnants KW - ISM: clouds KW - errata, addenda Y1 - 2015 U6 - https://doi.org/10.1051/0004-6361/201425070e SN - 1432-0746 VL - 580 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Soliveres, Santiago A1 - Manning, Peter A1 - Prati, Daniel A1 - Gossner, Martin M. A1 - Alt, Fabian A1 - Arndt, Hartmut A1 - Baumgartner, Vanessa A1 - Binkenstein, Julia A1 - Birkhofer, Klaus A1 - Blaser, Stefan A1 - Bluethgen, Nico A1 - Boch, Steffen A1 - Boehm, Stefan A1 - Boerschig, Carmen A1 - Buscot, Francois A1 - Diekoetter, Tim A1 - Heinze, Johannes A1 - Hoelzel, Norbert A1 - Jung, Kirsten A1 - Klaus, Valentin H. A1 - Klein, Alexandra-Maria A1 - Kleinebecker, Till A1 - Klemmer, Sandra A1 - Krauss, Jochen A1 - Lange, Markus A1 - Morris, E. Kathryn A1 - Mueller, Joerg A1 - Oelmann, Yvonne A1 - Overmann, Jörg A1 - Pasalic, Esther A1 - Renner, Swen C. A1 - Rillig, Matthias C. A1 - Schaefer, H. Martin A1 - Schloter, Michael A1 - Schmitt, Barbara A1 - Schoening, Ingo A1 - Schrumpf, Marion A1 - Sikorski, Johannes A1 - Socher, Stephanie A. A1 - Solly, Emily F. A1 - Sonnemann, Ilja A1 - Sorkau, Elisabeth A1 - Steckel, Juliane A1 - Steffan-Dewenter, Ingolf A1 - Stempfhuber, Barbara A1 - Tschapka, Marco A1 - Tuerke, Manfred A1 - Venter, Paul A1 - Weiner, Christiane N. A1 - Weisser, Wolfgang W. A1 - Werner, Michael A1 - Westphal, Catrin A1 - Wilcke, Wolfgang A1 - Wolters, Volkmar A1 - Wubet, Tesfaye A1 - Wurst, Susanne A1 - Fischer, Markus A1 - Allan, Eric T1 - Locally rare species influence grassland ecosystem multifunctionality JF - Philosophical transactions of the Royal Society of London : B, Biological sciences N2 - Species diversity promotes the delivery of multiple ecosystem functions (multifunctionality). However, the relative functional importance of rare and common species in driving the biodiversity multifunctionality relationship remains unknown. We studied the relationship between the diversity of rare and common species (according to their local abundances and across nine different trophic groups), and multifunctionality indices derived from 14 ecosystem functions on 150 grasslands across a land use intensity (LUI) gradient. The diversity of above- and below-ground rare species had opposite effects, with rare above-ground species being associated with high levels of multifunctionality, probably because their effects on different functions did not trade off against each other. Conversely, common species were only related to average, not high, levels of multifunctionality, and their functional effects declined with LUI. Apart from the community level effects of diversity, we found significant positive associations between the abundance of individual species and multifunctionality in 6% of the species tested. Species specific functional effects were best predicted by their response to LUI: species that declined in abundance with land use intensification were those associated with higher levels of multifunctionality. Our results highlight the importance of rare species for ecosystem multifunctionality and help guiding future conservation priorities. KW - biodiversity KW - common species KW - ecosystem function KW - identity hypothesis KW - land use KW - multitrophic Y1 - 2016 U6 - https://doi.org/10.1098/rstb.2015.0269 SN - 0962-8436 SN - 1471-2970 VL - 371 SP - 3175 EP - 3185 PB - Royal Society CY - London ER - TY - JOUR A1 - Allan, Eric A1 - Bossdorf, Oliver A1 - Dormann, Carsten F. A1 - Prati, Daniel A1 - Gossner, Martin M. A1 - Tscharntke, Teja A1 - Blüthgen, Nico A1 - Bellach, Michaela A1 - Birkhofer, Klaus A1 - Boch, Steffen A1 - Böhm, Stefan A1 - Börschig, Carmen A1 - Chatzinotas, Antonis A1 - Christ, Sabina A1 - Daniel, Rolf A1 - Diekötter, Tim A1 - Fischer, Christiane A1 - Friedl, Thomas A1 - Glaser, Karin A1 - Hallmann, Christine A1 - Hodac, Ladislav A1 - Hölzel, Norbert A1 - Jung, Kirsten A1 - Klein, Alexandra-Maria A1 - Klaus, Valentin H. A1 - Kleinebecker, Till A1 - Krauss, Jochen A1 - Lange, Markus A1 - Morris, E. Kathryn A1 - Müller, Jörg A1 - Nacke, Heiko A1 - Pasalic, Esther A1 - Rillig, Matthias C. A1 - Rothenwoehrer, Christoph A1 - Schally, Peter A1 - Scherber, Christoph A1 - Schulze, Waltraud X. A1 - Socher, Stephanie A. A1 - Steckel, Juliane A1 - Steffan-Dewenter, Ingolf A1 - Türke, Manfred A1 - Weiner, Christiane N. A1 - Werner, Michael A1 - Westphal, Catrin A1 - Wolters, Volkmar A1 - Wubet, Tesfaye A1 - Gockel, Sonja A1 - Gorke, Martin A1 - Hemp, Andreas A1 - Renner, Swen C. A1 - Schöning, Ingo A1 - Pfeiffer, Simone A1 - König-Ries, Birgitta A1 - Buscot, Francois A1 - Linsenmair, Karl Eduard A1 - Schulze, Ernst-Detlef A1 - Weisser, Wolfgang W. A1 - Fischer, Markus T1 - Interannual variation in land-use intensity enhances grassland multidiversity JF - Proceedings of the National Academy of Sciences of the United States of America N2 - Although temporal heterogeneity is a well-accepted driver of biodiversity, effects of interannual variation in land-use intensity (LUI) have not been addressed yet. Additionally, responses to land use can differ greatly among different organisms; therefore, overall effects of land-use on total local biodiversity are hardly known. To test for effects of LUI (quantified as the combined intensity of fertilization, grazing, and mowing) and interannual variation in LUI (SD in LUI across time), we introduce a unique measure of whole-ecosystem biodiversity, multidiversity. This synthesizes individual diversity measures across up to 49 taxonomic groups of plants, animals, fungi, and bacteria from 150 grasslands. Multidiversity declined with increasing LUI among grasslands, particularly for rarer species and aboveground organisms, whereas common species and belowground groups were less sensitive. However, a high level of interannual variation in LUI increased overall multidiversity at low LUI and was even more beneficial for rarer species because it slowed the rate at which the multidiversity of rare species declined with increasing LUI. In more intensively managed grasslands, the diversity of rarer species was, on average, 18% of the maximum diversity across all grasslands when LUI was static over time but increased to 31% of the maximum when LUI changed maximally over time. In addition to decreasing overall LUI, we suggest varying LUI across years as a complementary strategy to promote biodiversity conservation. KW - biodiversity loss KW - agricultural grasslands KW - Biodiversity Exploratories Y1 - 2014 U6 - https://doi.org/10.1073/pnas.1312213111 SN - 0027-8424 VL - 111 IS - 1 SP - 308 EP - 313 PB - National Acad. of Sciences CY - Washington ER -