TY - JOUR A1 - Esser, Günter A1 - Laucht, Manfred A1 - Schmidt, M. H. T1 - Modell der Entstehung von Substanzmissbrauch : stellt die Frühkindheit die Weichen? Y1 - 2005 SN - 3-525-46237-9 ER - TY - JOUR A1 - Ihle, Wolfgang A1 - Esser, Günter A1 - Schmidt, M. H. T1 - Aggressiv-dissoziale Störungen und rechtsextreme Einstellungen : Prävalenz, Geschlechtsunterschiede, Verlauf und Risikofaktoren Y1 - 2005 ER - TY - JOUR A1 - Wilke, Max A1 - Partzsch, G. M. A1 - Schmidt, C. A1 - Farges, Francois T1 - In-situ study of the iron species in silicate melts Y1 - 2004 SN - 0016-7037 ER - TY - JOUR A1 - Kress, H. A1 - Jarrin, A. A1 - Thuroff, E. A1 - Saunders, R. A1 - Weise, C. A1 - Schmidt am Busch, Marcel A1 - Knapp, E. W. A1 - Wedde, M. A1 - Vilcinskas, Andreas T1 - A Kunitz type protease inhibitor related protein is synthesized in Drosophila prepupal salivary glands and released into the moulting fluid during pupation N2 - From the Drosophila virilis late puff region 31C, we microcloned two neighbouring genes, Kil-1 and Kil-2, that encode putative Kunitz serine protease inhibitor like proteins. The Kil-1 gene is expressed exclusively in prepupal salivary glands. Using a size mutant of the KIL-1 protein and MALDI-TOF analysis, we demonstrate that during pupation this protein is released from the prepupal salivary glands into the pupation fluid covering the surface of the pupa. 3-D- structure predictions are consistent with the known crystal structure of the human Kunitz type protease inhibitor 2KNT. This is the first experimental proof for the extra-corporal presence of a distinct Drosophila prepupal salivary gland protein. Possible functions of KIL-1 in the context of the control of proteolytic activities in the pupation fluid are discussed. (C) 2004 Elsevier Ltd. All rights reserved Y1 - 2004 SN - 0965-1748 ER - TY - JOUR A1 - Esser, Günter A1 - Blanz, Bernhard A1 - Ihle, Wolfgang A1 - Schmidt, M. H. T1 - Modell und Entstehung des Substanzmissbrauchs Y1 - 2004 SN - 3-525-49075-6 ER - TY - JOUR A1 - Ihle, Wolfgang A1 - Esser, Günter A1 - Laucht, Manfred A1 - Schmidt, M. H. T1 - Depressive Störungen und aggressiv-dissoziale Störungen im Kindes- und Jugendalter : Prävalenz, Verlauf und Risikofaktoren Y1 - 2004 ER - TY - JOUR A1 - Laucht, Manfred A1 - Schmidt, M. H. A1 - Esser, Günter T1 - The development of at-risk children in early life Y1 - 2004 ER - TY - JOUR A1 - Rickert, D. A1 - Lendlein, Andreas A1 - Schmidt, A. M. A1 - Kelch, S. A1 - Roehlke, W. A1 - Fuhrmann, R. A1 - Franke, R. P. T1 - In vitro cytotoxicity testing of AB-polymer networks based on oligo(epsilon-caprolactone) segments after different sterilization techniques Y1 - 2003 ER - TY - JOUR A1 - Gordon, M. K. A1 - Krivov, Alexander V. A1 - Schmidt, Jürgen A1 - Spahn, Frank T1 - Planetary rings Y1 - 2002 ER - TY - JOUR A1 - Gorbatenko, M. V. A1 - Pushkin, A. V. A1 - Schmidt, Hans-Jürgen T1 - On a relation between the Bach equation and the equation of geometrodynamics N2 - The Bach equation and the equation of geometrodynamics are based on two quite different physical motivations, but in both approaches, the conformal properties of gravitation plays the key role. In this paper we present an analysis of the relation between these two equations and show that the solutions of the equation of geometrodynamics are of a more general nature. We show the following non-trivial result: there exists a conformally invariant Lagrangian, whose field equation generalizes the Bach equation and has as solutions those Ricci tensors which are solutions to the equation of geometrodynamics. Y1 - 2002 ER - TY - JOUR A1 - Grätz, Fabio M. A1 - Seiß, Martin A1 - Schmidt, Jürgen A1 - Colwell, Joshua A1 - Spahn, Frank T1 - Sharp Gap Edges in Dense Planetary Rings BT - an Axisymmetric Diffusion Model JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - One of the most intriguing facets of Saturn's rings are the sharp edges of gaps in the rings where the surface density abruptly drops to zero. This is despite of the fact that the range over which a moon transfers angular momentum onto the ring material is much larger. Recent UVIS-scans of the edges of the Encke and Keeler gap show that this drop occurs over a range approximately equal to the rings' thickness. Borderies et al. show that this striking feature is likely related to the local reversal of the usually outward directed viscous transport of angular momentum in strongly perturbed regions. In this article we revise the Borderies et al. model using a granular flow model to define the shear and bulk viscosities, ν and ζ, and incorporate the angular momentum flux reversal effect into the axisymmetric diffusion model we developed for gaps in dense planetary rings. Finally, we apply our model to the Encke and Keeler division in order to estimate the shear and bulk viscosities in the vicinity of both gaps KW - celestial mechanics KW - diffusion KW - hydrodynamics KW - planets and satellites: rings KW - scattering Y1 - 2019 U6 - https://doi.org/10.3847/1538-4357/ab007e SN - 0004-637X SN - 1538-4357 VL - 872 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Schmidt, Katja A1 - Martin-Lopez, Berta A1 - Phillips, Peter M. A1 - Julius, Eike A1 - Makan, Neville A1 - Walz, Ariane T1 - Key landscape features in the provision of ecosystem services BT - Insights for management JF - Land use policy N2 - Whereas ecosystem service research is increasingly being promoted in science and policy, the utilisation of ecosystem services knowledge remains largely underexplored for regional ecosystem management. To overcome the mere generation of knowledge and contribute to decision-making, scientists are facing the challenge of articulating specific implications of the ecosystem service approach for practical land use management. In this contribution, we compare the results of participatory mapping of ecosystem services with the existing management plan for the Pentland Hills Regional Park (Scotland, UK) to inform its future management plan. By conducting participatory mapping in a workshop with key stakeholders (n = 20), we identify hotspots of ecosystem services and the landscape features underpinning such hotspots. We then analyse to what extent these landscape features are the focus of the current management plan. We found a clear mismatch between the key landscape features underpinning the provision of ecosystem services and the management strategy suggested. Our findings allow for a better understanding of the required focus of future land use management to account for ecosystem services. KW - Participatory mapping KW - PPGIS KW - Landscape features KW - Content analysis KW - Land use management KW - Operationalisation Y1 - 2018 U6 - https://doi.org/10.1016/j.landusepol.2018.12.022 SN - 0264-8377 SN - 1873-5754 VL - 82 SP - 353 EP - 366 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Knebel, Constanze A1 - Neeb, Jannika A1 - Zahn, Elisabeth A1 - Schmidt, Flavia A1 - Carazo, Alejandro A1 - Holas, Ondej A1 - Pavek, Petr A1 - Püschel, Gerhard Paul A1 - Zanger, Ulrich M. A1 - Süssmuth, Roderich A1 - Lampen, Alfonso A1 - Marx-Stoelting, Philip A1 - Braeuning, Albert T1 - Unexpected Effects of Propiconazole, Tebuconazole, and Their Mixture on the Receptors CAR and PXR in Human Liver Cells JF - Toxicological sciences N2 - Analyzing mixture toxicity requires an in-depth understanding of the mechanisms of action of its individual components. Substances with the same target organ, same toxic effect and same mode of action (MoA) are believed to cause additive effects, whereas substances with different MoAs are assumed to act independently. Here, we tested 2 triazole fungicides, propiconazole, and tebuconazole (Te), for individual and combined effects on liver toxicity-related endpoints. Both triazoles are proposed to belong to the same cumulative assessment group and are therefore thought to display similar and additive behavior. Our data show that Te is an antagonist of the constitutive androstane receptor (CAR) in rats and humans, while propiconazole is an agonist of this receptor. Both substances activate the pregnane X-receptor (PXR) and further induce mRNA expression of CYP3A4. CYP3A4 enzyme activity, however, is inhibited by propiconazole. For common targets of PXR and CAR, the activation of PXR by Te overrides CAR inhibition. In summary, propiconazole and Te affect different hepatotoxicity-relevant cellular targets and, depending on the individual endpoint analyzed, act via similar or dissimilar mechanisms. The use of molecular data based on research in human cell systems extends the picture to refine cumulative assessment group grouping and substantially contributes to the understanding of mixture effects of chemicals in biological systems. KW - triazole fungicides KW - constitutive androstane receptor KW - pregnane X-receptor KW - enzyme induction KW - liver toxicity KW - mixtures Y1 - 2018 U6 - https://doi.org/10.1093/toxsci/kfy026 SN - 1096-6080 SN - 1096-0929 VL - 163 IS - 1 SP - 170 EP - 181 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Rader, Oliver A1 - Fauth, K. A1 - Gould, C. A1 - Ruster, C. A1 - Schott, G. M. A1 - Schmidt, G. A1 - Brunner, K. A1 - Molenkamp, Laurens W. A1 - Schutz, G. A1 - Kronast, F. A1 - Durr, H. A. A1 - Eberhardt, W. A1 - Gudat, Wolfgang T1 - Identification of extrinsic Mn contributions in Ga1-xMnxAs by field-dependent magnetic circular X-ray dichroism N2 - We combine sensitivity to atomic number, chemical shifts, probing depth, and magnetic order in a field- dependent magnetic circular X-ray dichroism study at the Mn L-edge of the diluted ferromagnetic semiconductor Ga1-xMnxAs and observe different Mn constituents: ferromagnetic Mn with an n(d) > 5 lineshape and paramagnetic Mn with distinct n(d) = 5 lineshape. The paramagnetic Mn is assigned to interstitials with surface segregation tendency. (c) 2005 Elsevier B.V. All rights reserved Y1 - 2005 SN - 0368-2048 ER - TY - JOUR A1 - Schröder, Astrid A1 - Grimm, Angela A1 - Schulz, Petra A1 - Heide, Judith A1 - Frank, Ulrike A1 - Wahl, Michael A1 - Lampe, Leonie A1 - Fieder, Nora A1 - Krajenbrink, Trudy A1 - Nickels, Lyndsey A1 - Bykova, Ksenia A1 - Wilzek, Alexa A1 - van den Engl-Hoek, Lenie A1 - Huckabee, Maggie-Lee A1 - Balzer, Julia A1 - Ebert, Susanne A1 - Kaps, Hella A1 - Matteschk, Maria A1 - Tzschöckel, Katharina Andrea A1 - Dressel, Katharina A1 - Kröger, Bernd J. A1 - Diwoky, Laura Cassandra A1 - Breitenstein, Sarah A1 - Bruno, Giulia A1 - Lassotta, Romy A1 - Adani, Flavia A1 - Ferchland, Lisa A1 - Baatz, Charlotte A1 - Netzebandt, Jonka A1 - Heyde, Cornelia J. A1 - Cleland, Joanne A1 - Scobbie, James M. A1 - Roxburgh, Zoe A1 - Schmidt, Jessica ED - Adelt, Anne ED - Yetim, Özlem ED - Otto, Constanze ED - Fritzsche, Tom T1 - Spektrum Patholinguistik Band 10. Schwerpunktthema: Panorama Patholinguistik: Sprachwissenschaft trifft Sprachtherapie N2 - Das 10. Herbsttreffen Patholinguistik mit dem Schwerpunktthema »Panorama Patholinguistik: Sprachwissenschaft trifft Sprachtherapie« fand am 19.11.2016 in Potsdam statt. Das Herbsttreffen wird seit 2007 jährlich vom Verband für Patholinguistik e.V. (vpl) durchgeführt. Der vorliegende Tagungsband beinhaltet die vier Hauptvorträge zum Schwerpunktthema sowie Beiträge zu den Kurzvorträgen »Patholinguistik im Fokus« und der Posterpräsentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis. N2 - The Tenth Autumn Meeting Patholinguistics (Herbsttreffen Patholinguistik) with its main topic »Panorama Patholinguistics: Linguistics meets speech/language therapy« took place in Potsdam on November 19 2016. This annual meeting has been organised since 2007 by the Association for Patholinguistics (Verband für Patholinguistik e.V./vpl). The present proceedings contain the four keynote talks on the main topic as well as contributions from the short talks in the section »Patholinguistics in Focus« and from the poster session covering a broad range of areas in speech/language therapy research and practice. T3 - Spektrum Patholinguistik - 10 KW - Patholinguistik KW - Sprachtherapie KW - Spracherwerb KW - Aphasie KW - Schluckstörungen KW - Lese-Rechtschreibschwierigkeiten KW - patholinguistics KW - speech/language therapy KW - language acquisition KW - ahasia KW - dysphagia KW - dyslexia Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-397019 SN - 978-3-86956-404-3 SN - 1866-9085 SN - 1866-9433 IS - 10 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Tötzke, Christian A1 - Gaiselmann, G. A1 - Osenberg, M. A1 - Arlt, T. A1 - Markötter, H. A1 - Hilger, A. A1 - Kupsch, Andreas A1 - Müller, B. R. A1 - Schmidt, V. A1 - Lehnert, W. A1 - Manke, Ingo T1 - Influence of hydrophobic treatment on the structure of compressed gas diffusion layers JF - Journal of power sources : the international journal on the science and technology of electrochemical energy systems N2 - Carbon fiber based felt materials are widely used as gas diffusion layer (GDL) in fuel cells. Their transport properties can be adjusted by adding hydrophobic agents such as polytetrafluoroethylene (PTFE). We present a synchrotron X-ray tomographic study on the felt material Freudenberg H2315 with different PIPE finishing. In this study, we analyze changes in microstructure and shape of GDLs at increasing degree of compression which are related to their specific PTFE load. A dedicated compression device mimicking the channel-land pattern of the flowfield is used to reproduce the inhomogeneous compression found in a fuel cell. Transport relevant geometrical parameters such as porosity, pore size distribution and geometric tortuosity are calculated and consequences for media transport discussed. PTFE finishing results in a marked change of shape of compressed GDLs: surface is smoothed and the invasion of GDL fibers into the flow field channel strongly mitigated. Furthermore, the PTFE impacts the microstructure of the compressed GDL. The number of available wide transport paths is significantly increased as compared to the untreated material. These changes improve the transport capacity liquid water through the GDL and promote the discharge of liquid water droplets from the cell. (C) 2016 Elsevier B.V. All rights reserved. KW - Gas diffusion layer KW - Synchrotron tomography KW - Compression KW - Hydrophobic treatment KW - Water transport Y1 - 2016 U6 - https://doi.org/10.1016/j.jpowsour.2016.05.118 SN - 0378-7753 SN - 1873-2755 VL - 324 SP - 625 EP - 636 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Pietz, J. A1 - Fätkenheuer, Brigitte A1 - Burgard, P. A1 - Armbruster, M. A1 - Esser, Günter A1 - Schmidt, Martin H. T1 - Psychiatric disorders in adult patients with early-treated phenylketonuria Y1 - 1997 ER - TY - JOUR A1 - Pade, Sylvia A1 - Schmidt, Hartmut A1 - Stumpe, Joachim A1 - Fischer, Thomas M. T1 - (Micro-)fluorescence spectroscopy of side chain polymers with bezanilide moieties Y1 - 1996 ER - TY - JOUR A1 - Tobie, Gabriel A1 - Giese, Bernd A1 - Hurford, Terry Anthony A1 - Lopes, Rosaly M. A1 - Nimmo, Francis A1 - Postberg, Frank A1 - Retherford, Kurt D. A1 - Schmidt, Jürgen A1 - Spencer, John R. A1 - Tokano, Tetsuya A1 - Turtle, Elizabeth P. T1 - Surface, subsurface and atmosphere exchanges on the satellites of the outer solar system N2 - The surface morphology of icy moons is affected by several processes implicating exchanges between their subsurfaces and atmospheres (if any). The possible exchange of material between the subsurface and the surface is mainly determined by the mechanical properties of the lithosphere, which isolates the deep, warm and ductile ice material from the cold surface conditions. Exchanges through this layer occur only if it is sufficiently thin and/or if it is fractured owing to tectonic stresses, melt intrusion or impact cratering. If such conditions are met, cryomagma can be released, erupting fresh volatile-rich materials onto the surface. For a very few icy moons (Titan, Triton, Enceladus), the emission of gas associated with cryovolcanic activity is sufficiently large to generate an atmosphere, either long- lived or transient. For those moons, atmosphere-driven processes such as cryovolcanic plume deposition, phase transitions of condensable materials and wind interactions continuously re-shape their surfaces, and are able to transport cryovolcanically generated materials on a global scale. In this chapter, we discuss the physics of these different exchange processes and how they affect the evolution of the satellites' surfaces. Y1 - 2010 UR - http://www.springerlink.com/content/102996 U6 - https://doi.org/10.1007/s11214-010-9641-3 SN - 0038-6308 ER - TY - BOOK A1 - Rauh, Hellgard A1 - Schmidt-Denter, U. A1 - Perrez, M. A1 - Krapp, A. T1 - Psychologie in Erziehung und Unterricht : Zeitschrift für Forschung und Praxis Y1 - 1995 SN - 0342-183X PB - Reinhardt CY - München ER -