TY - JOUR A1 - Weber, Michael H. A1 - Abu-Ayyash, Khalil A1 - Abueladas, Abdel-Rahman A1 - Agnon, Amotz A1 - Al-Amoush, H. A1 - Babeyko, Andrey A1 - Bartov, Yosef A1 - Baumann, M. A1 - Ben-Avraham, Zvi A1 - Bock, Günter A1 - Bribach, Jens A1 - El-Kelani, R. A1 - Forster, A. A1 - Förster, Hans-Jürgen A1 - Frieslander, U. A1 - Garfunkel, Zvi A1 - Grunewald, Steffen A1 - Gotze, Hans-Jürgen A1 - Haak, Volker A1 - Haberland, Christian A1 - Hassouneh, Mohammed A1 - Helwig, S. A1 - Hofstetter, Alfons A1 - Jackel, K. H. A1 - Kesten, Dagmar A1 - Kind, Rainer A1 - Maercklin, Nils A1 - Mechie, James A1 - Mohsen, Amjad A1 - Neubauer, F. M. A1 - Oberhänsli, Roland A1 - Qabbani, I. A1 - Ritter, O. A1 - Rumpker, G. A1 - Rybakov, M. A1 - Ryberg, Trond A1 - Scherbaum, Frank A1 - Schmidt, J. A1 - Schulze, A. A1 - Sobolev, Stephan Vladimir A1 - Stiller, M. A1 - Th, T1 - The crustal structure of the Dead Sea Transform N2 - To address one of the central questions of plate tectonics-How do large transform systems work and what are their typical features?-seismic investigations across the Dead Sea Transform (DST), the boundary between the African and Arabian plates in the Middle East, were conducted for the first time. A major component of these investigations was a combined reflection/ refraction survey across the territories of Palestine, Israel and Jordan. The main results of this study are: (1) The seismic basement is offset by 3-5 km under the DST, (2) The DST cuts through the entire crust, broadening in the lower crust, (3) Strong lower crustal reflectors are imaged only on one side of the DST, (4) The seismic velocity sections show a steady increase in the depth of the crust-mantle transition (Moho) from 26 km at the Mediterranean to 39 km under the Jordan highlands, with only a small but visible, asymmetric topography of the Moho under the DST. These observations can be linked to the left-lateral movement of 105 km of the two plates in the last 17 Myr, accompanied by strong deformation within a narrow zone cutting through the entire crust. Comparing the DST and the San Andreas Fault (SAF) system, a strong asymmetry in subhorizontal lower crustal reflectors and a deep reaching deformation zone both occur around the DST and the SAF. The fact that such lower crustal reflectors and deep deformation zones are observed in such different transform systems suggests that these structures are possibly fundamental features of large transform plate boundaries Y1 - 2004 ER - TY - JOUR A1 - Dengler, Jürgen A1 - Wagner, Viktoria A1 - Dembicz, Iwona A1 - Garcia-Mijangos, Itziar A1 - Naqinezhad, Alireza A1 - Boch, Steffen A1 - Chiarucci, Alessandro A1 - Conradi, Timo A1 - Filibeck, Goffredo A1 - Guarino, Riccardo A1 - Janisova, Monika A1 - Steinbauer, Manuel J. A1 - Acic, Svetlana A1 - Acosta, Alicia T. R. A1 - Akasaka, Munemitsu A1 - Allers, Marc-Andre A1 - Apostolova, Iva A1 - Axmanova, Irena A1 - Bakan, Branko A1 - Baranova, Alina A1 - Bardy-Durchhalter, Manfred A1 - Bartha, Sandor A1 - Baumann, Esther A1 - Becker, Thomas A1 - Becker, Ute A1 - Belonovskaya, Elena A1 - Bengtsson, Karin A1 - Benito Alonso, Jose Luis A1 - Berastegi, Asun A1 - Bergamini, Ariel A1 - Bonini, Ilaria A1 - Bruun, Hans Henrik A1 - Budzhak, Vasyl A1 - Bueno, Alvaro A1 - Antonio Campos, Juan A1 - Cancellieri, Laura A1 - Carboni, Marta A1 - Chocarro, Cristina A1 - Conti, Luisa A1 - Czarniecka-Wiera, Marta A1 - De Frenne, Pieter A1 - Deak, Balazs A1 - Didukh, Yakiv P. A1 - Diekmann, Martin A1 - Dolnik, Christian A1 - Dupre, Cecilia A1 - Ecker, Klaus A1 - Ermakov, Nikolai A1 - Erschbamer, Brigitta A1 - Escudero, Adrian A1 - Etayo, Javier A1 - Fajmonova, Zuzana A1 - Felde, Vivian A. A1 - Fernandez Calzado, Maria Rosa A1 - Finckh, Manfred A1 - Fotiadis, Georgios A1 - Fracchiolla, Mariano A1 - Ganeva, Anna A1 - Garcia-Magro, Daniel A1 - Gavilan, Rosario G. A1 - Germany, Markus A1 - Giladi, Itamar A1 - Gillet, Francois A1 - Giusso del Galdo, Gian Pietro A1 - Gonzalez, Jose M. A1 - Grytnes, John-Arvid A1 - Hajek, Michal A1 - Hajkova, Petra A1 - Helm, Aveliina A1 - Herrera, Mercedes A1 - Hettenbergerova, Eva A1 - Hobohm, Carsten A1 - Huellbusch, Elisabeth M. A1 - Ingerpuu, Nele A1 - Jandt, Ute A1 - Jeltsch, Florian A1 - Jensen, Kai A1 - Jentsch, Anke A1 - Jeschke, Michael A1 - Jimenez-Alfaro, Borja A1 - Kacki, Zygmunt A1 - Kakinuma, Kaoru A1 - Kapfer, Jutta A1 - Kavgaci, Ali A1 - Kelemen, Andras A1 - Kiehl, Kathrin A1 - Koyama, Asuka A1 - Koyanagi, Tomoyo F. A1 - Kozub, Lukasz A1 - Kuzemko, Anna A1 - Kyrkjeeide, Magni Olsen A1 - Landi, Sara A1 - Langer, Nancy A1 - Lastrucci, Lorenzo A1 - Lazzaro, Lorenzo A1 - Lelli, Chiara A1 - Leps, Jan A1 - Loebel, Swantje A1 - Luzuriaga, Arantzazu L. A1 - Maccherini, Simona A1 - Magnes, Martin A1 - Malicki, Marek A1 - Marceno, Corrado A1 - Mardari, Constantin A1 - Mauchamp, Leslie A1 - May, Felix A1 - Michelsen, Ottar A1 - Mesa, Joaquin Molero A1 - Molnar, Zsolt A1 - Moysiyenko, Ivan Y. A1 - Nakaga, Yuko K. A1 - Natcheva, Rayna A1 - Noroozi, Jalil A1 - Pakeman, Robin J. A1 - Palpurina, Salza A1 - Partel, Meelis A1 - Paetsch, Ricarda A1 - Pauli, Harald A1 - Pedashenko, Hristo A1 - Peet, Robert K. A1 - Pielech, Remigiusz A1 - Pipenbaher, Natasa A1 - Pirini, Chrisoula A1 - Pleskova, Zuzana A1 - Polyakova, Mariya A. A1 - Prentice, Honor C. A1 - Reinecke, Jennifer A1 - Reitalu, Triin A1 - Pilar Rodriguez-Rojo, Maria A1 - Rolecek, Jan A1 - Ronkin, Vladimir A1 - Rosati, Leonardo A1 - Rosen, Ejvind A1 - Ruprecht, Eszter A1 - Rusina, Solvita A1 - Sabovljevic, Marko A1 - Maria Sanchez, Ana A1 - Savchenko, Galina A1 - Schuhmacher, Oliver A1 - Skornik, Sonja A1 - Sperandii, Marta Gaia A1 - Staniaszek-Kik, Monika A1 - Stevanovic-Dajic, Zora A1 - Stock, Marin A1 - Suchrow, Sigrid A1 - Sutcliffe, Laura M. E. A1 - Swacha, Grzegorz A1 - Sykes, Martin A1 - Szabo, Anna A1 - Talebi, Amir A1 - Tanase, Catalin A1 - Terzi, Massimo A1 - Tolgyesi, Csaba A1 - Torca, Marta A1 - Torok, Peter A1 - Tothmeresz, Bela A1 - Tsarevskaya, Nadezda A1 - Tsiripidis, Ioannis A1 - Tzonev, Rossen A1 - Ushimaru, Atushi A1 - Valko, Orsolya A1 - van der Maarel, Eddy A1 - Vanneste, Thomas A1 - Vashenyak, Iuliia A1 - Vassilev, Kiril A1 - Viciani, Daniele A1 - Villar, Luis A1 - Virtanen, Risto A1 - Kosic, Ivana Vitasovic A1 - Wang, Yun A1 - Weiser, Frank A1 - Went, Julia A1 - Wesche, Karsten A1 - White, Hannah A1 - Winkler, Manuela A1 - Zaniewski, Piotr T. A1 - Zhang, Hui A1 - Ziv, Yaron A1 - Znamenskiy, Sergey A1 - Biurrun, Idoia T1 - GrassPlot - a database of multi-scale plant diversity in Palaearctic grasslands JF - Phytocoenologia N2 - GrassPlot is a collaborative vegetation-plot database organised by the Eurasian Dry Grassland Group (EDGG) and listed in the Global Index of Vegetation-Plot Databases (GIVD ID EU-00-003). GrassPlot collects plot records (releves) from grasslands and other open habitats of the Palaearctic biogeographic realm. It focuses on precisely delimited plots of eight standard grain sizes (0.0001; 0.001;... 1,000 m(2)) and on nested-plot series with at least four different grain sizes. The usage of GrassPlot is regulated through Bylaws that intend to balance the interests of data contributors and data users. The current version (v. 1.00) contains data for approximately 170,000 plots of different sizes and 2,800 nested-plot series. The key components are richness data and metadata. However, most included datasets also encompass compositional data. About 14,000 plots have near-complete records of terricolous bryophytes and lichens in addition to vascular plants. At present, GrassPlot contains data from 36 countries throughout the Palaearctic, spread across elevational gradients and major grassland types. GrassPlot with its multi-scale and multi-taxon focus complements the larger international vegetationplot databases, such as the European Vegetation Archive (EVA) and the global database " sPlot". Its main aim is to facilitate studies on the scale-and taxon-dependency of biodiversity patterns and drivers along macroecological gradients. GrassPlot is a dynamic database and will expand through new data collection coordinated by the elected Governing Board. We invite researchers with suitable data to join GrassPlot. Researchers with project ideas addressable with GrassPlot data are welcome to submit proposals to the Governing Board. KW - biodiversity KW - European Vegetation Archive (EVA) KW - Eurasian Dry Grassland Group (EDGG) KW - grassland vegetation KW - GrassPlot KW - macroecology KW - multi-taxon KW - nested plot KW - scale-dependence KW - species-area relationship (SAR) KW - sPlot KW - vegetation-plot database Y1 - 2018 U6 - https://doi.org/10.1127/phyto/2018/0267 SN - 0340-269X VL - 48 IS - 3 SP - 331 EP - 347 PB - Cramer CY - Stuttgart ER - TY - GEN A1 - Baumann, Tobias A1 - Arndt, Katja Maren A1 - Müller, Kristian M. T1 - Directional cloning of DNA fragments using deoxyinosine-containing oligonucleotides and endonuclease V T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Background: DNA fragments carrying internal recognition sites for the restriction endonucleases intended for cloning into a target plasmid pose a challenge for conventional cloning. Results: A method for directional insertion of DNA fragments into plasmid vectors has been developed. The target sequence is amplified from a template DNA sample by PCR using two oligonucleotides each containing a single deoxyinosine base at the third position from the 5' end. Treatment of such PCR products with endonuclease V generates 3' protruding ends suitable for ligation with vector fragments created by conventional restriction endonuclease reactions. Conclusions: The developed approach generates terminal cohesive ends without the use of Type II restriction endonucleases, and is thus independent from the DNA sequence. Due to PCR amplification, minimal amounts of template DNA are required. Using the robust Taq enzyme or a proofreading Pfu DNA polymerase mutant, the method is applicable to a broad range of insert sequences. Appropriate primer design enables direct incorporation of terminal DNA sequence modifications such as tag addition, insertions, deletions and mutations into the cloning strategy. Further, the restriction sites of the target plasmid can be either retained or removed. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 983 KW - cohesive ends KW - DNA cleavage KW - genetic vectors KW - modified primers KW - molecular methods KW - polymerase chain reaction KW - recombinant Escherichia coli KW - restriction enzymes Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-431085 SN - 1866-8372 IS - 983 ER - TY - JOUR A1 - Baumann, Tobias A1 - Arndt, Katja Maren A1 - Müller, Kristian M. T1 - Directional cloning of DNA fragments using deoxyinosine-containing oligonucleotides and endonuclease V JF - BMC biotechnology N2 - Background: DNA fragments carrying internal recognition sites for the restriction endonucleases intended for cloning into a target plasmid pose a challenge for conventional cloning. Results: A method for directional insertion of DNA fragments into plasmid vectors has been developed. The target sequence is amplified from a template DNA sample by PCR using two oligonucleotides each containing a single deoxyinosine base at the third position from the 5' end. Treatment of such PCR products with endonuclease V generates 3' protruding ends suitable for ligation with vector fragments created by conventional restriction endonuclease reactions. Conclusions: The developed approach generates terminal cohesive ends without the use of Type II restriction endonucleases, and is thus independent from the DNA sequence. Due to PCR amplification, minimal amounts of template DNA are required. Using the robust Taq enzyme or a proofreading Pfu DNA polymerase mutant, the method is applicable to a broad range of insert sequences. Appropriate primer design enables direct incorporation of terminal DNA sequence modifications such as tag addition, insertions, deletions and mutations into the cloning strategy. Further, the restriction sites of the target plasmid can be either retained or removed. KW - Cohesive ends KW - DNA cleavage KW - Genetic vectors KW - Modified primers KW - Molecular methods KW - Polymerase chain reaction KW - Recombinant Escherichia coli KW - Restriction enzymes Y1 - 2013 U6 - https://doi.org/10.1186/1472-6750-13-81 SN - 1472-6750 VL - 13 IS - 10 PB - BioMed Central CY - London ER - TY - JOUR A1 - Jedrusik-Bode, Monika A1 - Studencka, Maja A1 - Smolka, Christian A1 - Baumann, Tobias A1 - Schmidt, Henning A1 - Kampf, Jan A1 - Paap, Franziska A1 - Martin, Sophie A1 - Tazi, Jamal A1 - Müller, Kristian M. A1 - Krüger, Marcus A1 - Braun, Thomas A1 - Bober, Eva T1 - The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals JF - Journal of cell science N2 - SIRT6 is a NAD(+)-dependent deacetylase that modulates chromatin structure and safeguards genomic stability. Until now, SIRT6 has been assigned to the nucleus and only nuclear targets of SIRT6 are known. Here, we demonstrate that in response to stress, C. elegans SIR-2.4 and its mammalian orthologue SIRT6 localize to cytoplasmic stress granules, interact with various stress granule components and induce their assembly. Loss of SIRT6 or inhibition of its catalytic activity in mouse embryonic fibroblasts impairs stress granule formation and delays disassembly during recovery, whereas deficiency of SIR-2.4 diminishes maintenance of P granules and decreases survival of C. elegans under stress conditions. Our findings uncover a novel, evolutionary conserved function of SIRT6 in the maintenance of stress granules in response to stress. KW - C. elegans KW - G3BP KW - SIRT6 KW - Sirtuins KW - Stress KW - Stress granules Y1 - 2013 U6 - https://doi.org/10.1242/jcs.130708 SN - 0021-9533 SN - 1477-9137 VL - 126 IS - 22 SP - 5166 EP - + PB - Company of Biologists Limited CY - Cambridge ER - TY - JOUR A1 - Baumann, Otto A1 - Salvaterra, Paul M. A1 - Takeyasu, Kunio T1 - Developmental changes in beta-subunit composition of Na,K-ATPase in the Drosophila eye N2 - The Drosophila genome contains at least three loci for the Na,K-ATPase beta-subunit; however, only the protein products of nrv1 and nrv2 have been characterized hitherto. Here, we provide evidence that nrv3 also encodes for a functional Na,K-ATPase beta-subunit, as its protein product co-precipitates with the Na,K-ATPase alpha-subunit. Nrv3 expression in adult flies is restricted to the nervous system in which Nrv3 is enriched in selective types of sensory cells. Because Nrv3 expression is especially prominent in the compound eye, we have analyzed the subcellular and developmental distribution of Nrv3 within the visual cells and related this distribution to those of the alpha-subunit and of the beta-subunits Nrv1 and Nrv2. Prospective visual cells express Nrv2 in the third larval instar stage and during the first half of pupal development. During the last third of pupal life, Nrv3 gradually replaces Nrv2 as the Na,K-ATPase beta-subunit in the photoreceptor cells. Adult photoreceptors express Nrv3 as their major beta-subunit; the visual cells R1-R6 co-express Nrv2 at a low level, whereas R7 and R8 co-express Nrv1. Notably, beta-subunits do not co- distribute exactly with the alpha-subunit at some developmental stages, supporting the concept that the alpha-subunit and beta-subunit can exist in the plasma membrane without being engaged in alpha/beta heterodimers. The non-visual cells within the compound eye express almost exclusively Nrv2, which segregates together with the alpha-subunit to septate junctions throughout development. Y1 - 2010 UR - http://www.springerlink.com/content/100524 U6 - https://doi.org/10.1007/s00441-010-0948-x SN - 0302-766X ER - TY - JOUR A1 - Hagen, Sven A1 - Baumann, Tobias A1 - Wagner, Hanna J. A1 - Morath, Volker A1 - Kaufmann, Beate A1 - Fischer, Adrian A1 - Bergmann, Stefan A1 - Schindler, Patrick A1 - Arndt, Katja Maren A1 - Mueller, Kristian M. T1 - Modular adeno-associated virus (rAAV) vectors used for cellular virus-directed enzyme prodrug therapy JF - Scientific reports N2 - The pre-clinical and clinical development of viral vehicles for gene transfer increased in recent years, and a recombinant adeno-associated virus (rAAV) drug took center stage upon approval in the European Union. However, lack of standardization, inefficient purification methods and complicated retargeting limit general usability. We address these obstacles by fusing rAAV-2 capsids with two modular targeting molecules (DARPin or Affibody) specific for a cancer cell-surface marker (EGFR) while simultaneously including an affinity tag (His-tag) in a surface-exposed loop. Equipping these particles with genes coding for prodrug converting enzymes (thymidine kinase or cytosine deaminase) we demonstrate tumor marker specific transduction and prodrug-dependent apoptosis of cancer cells. Coding terminal and loop modifications in one gene enabled specific and scalable purification. Our genetic parts for viral production adhere to a standardized cloning strategy facilitating rapid prototyping of virus directed enzyme prodrug therapy (VDEPT). Y1 - 2014 U6 - https://doi.org/10.1038/srep03759 SN - 2045-2322 VL - 4 PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Kuekenshoener, Tim A1 - Hagemann, Urs B. A1 - Wohlwend, Daniel A1 - Raeuber, Christina A1 - Baumann, Tobias A1 - Keller, Sandro A1 - Einsle, Oliver A1 - Mueller, Kristian M. A1 - Arndt, Katja Maren T1 - Analysis of Selected and Designed Chimeric D- and L-alpha-Helix Assemblies JF - Biomacromolecules : an interdisciplinary journal focused at the interface of polymer science and the biological sciences N2 - D-Peptides have been attributed pharmacological advantages over regular L-peptides, yet design rules are largely unknown. Based on a designed coiled coil-like D/L heterotetramer, named L-Base/D-Acid, we generated a library offering alternative residues for interaction with the D-peptide. Phage display selection yielded one predominant peptide, named HelixA, that differed at 13 positions from the scaffold helix. In addition to the observed D-/L-heterotetramers, ratio-dependent intermediate states were detected by isothermal titration calorimetry. Importantly, the formation of the selected HelixA/D-Acid bundle passes through fewer intermediate states than L-Base/D-Acid. Back mutation of HelixA core residues to L-Base (HelixLL) revealed that the residues at e/g-positions are responsible for the different intermediates. Furthermore, a Val-core variant (PeptideVV) was completely devoid of binding D-Acid, whereas an Ile-core helix (HelixII) interacted with D-Acid in a significantly more specific complex than L-Base. Y1 - 2014 U6 - https://doi.org/10.1021/bm5006883 SN - 1525-7797 SN - 1526-4602 VL - 15 IS - 9 SP - 3296 EP - 3305 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Weber, Michael H. A1 - Wicks, Chuck A1 - Krüger, Frank A1 - Jahnke, Gunnar A1 - Baumann, M. T1 - Reply to comment on "Asymmetric radiation of seismic waves from an atoll : Nuclear tests in French Polynesia" by A. Douglas Y1 - 2000 ER - TY - BOOK A1 - Zhang, Shuhao A1 - Plauth, Max A1 - Eberhardt, Felix A1 - Polze, Andreas A1 - Lehmann, Jens A1 - Sejdiu, Gezim A1 - Jabeen, Hajira A1 - Servadei, Lorenzo A1 - Möstl, Christian A1 - Bär, Florian A1 - Netzeband, André A1 - Schmidt, Rainer A1 - Knigge, Marlene A1 - Hecht, Sonja A1 - Prifti, Loina A1 - Krcmar, Helmut A1 - Sapegin, Andrey A1 - Jaeger, David A1 - Cheng, Feng A1 - Meinel, Christoph A1 - Friedrich, Tobias A1 - Rothenberger, Ralf A1 - Sutton, Andrew M. A1 - Sidorova, Julia A. A1 - Lundberg, Lars A1 - Rosander, Oliver A1 - Sköld, Lars A1 - Di Varano, Igor A1 - van der Walt, Estée A1 - Eloff, Jan H. P. A1 - Fabian, Benjamin A1 - Baumann, Annika A1 - Ermakova, Tatiana A1 - Kelkel, Stefan A1 - Choudhary, Yash A1 - Cooray, Thilini A1 - Rodríguez, Jorge A1 - Medina-Pérez, Miguel Angel A1 - Trejo, Luis A. A1 - Barrera-Animas, Ari Yair A1 - Monroy-Borja, Raúl A1 - López-Cuevas, Armando A1 - Ramírez-Márquez, José Emmanuel A1 - Grohmann, Maria A1 - Niederleithinger, Ernst A1 - Podapati, Sasidhar A1 - Schmidt, Christopher A1 - Huegle, Johannes A1 - de Oliveira, Roberto C. L. A1 - Soares, Fábio Mendes A1 - van Hoorn, André A1 - Neumer, Tamas A1 - Willnecker, Felix A1 - Wilhelm, Mathias A1 - Kuster, Bernhard ED - Meinel, Christoph ED - Polze, Andreas ED - Beins, Karsten ED - Strotmann, Rolf ED - Seibold, Ulrich ED - Rödszus, Kurt ED - Müller, Jürgen T1 - HPI Future SOC Lab – Proceedings 2017 T1 - HPI Future SOC Lab – Proceedings 2017 N2 - The “HPI Future SOC Lab” is a cooperation of the Hasso Plattner Institute (HPI) and industry partners. Its mission is to enable and promote exchange and interaction between the research community and the industry partners. The HPI Future SOC Lab provides researchers with free of charge access to a complete infrastructure of state of the art hard and software. This infrastructure includes components, which might be too expensive for an ordinary research environment, such as servers with up to 64 cores and 2 TB main memory. The offerings address researchers particularly from but not limited to the areas of computer science and business information systems. Main areas of research include cloud computing, parallelization, and In-Memory technologies. This technical report presents results of research projects executed in 2017. Selected projects have presented their results on April 25th and November 15th 2017 at the Future SOC Lab Day events. N2 - Das Future SOC Lab am HPI ist eine Kooperation des Hasso-Plattner-Instituts mit verschiedenen Industriepartnern. Seine Aufgabe ist die Ermöglichung und Förderung des Austausches zwischen Forschungsgemeinschaft und Industrie. Am Lab wird interessierten Wissenschaftlern eine Infrastruktur von neuester Hard- und Software kostenfrei für Forschungszwecke zur Verfügung gestellt. Dazu zählen teilweise noch nicht am Markt verfügbare Technologien, die im normalen Hochschulbereich in der Regel nicht zu finanzieren wären, bspw. Server mit bis zu 64 Cores und 2 TB Hauptspeicher. Diese Angebote richten sich insbesondere an Wissenschaftler in den Gebieten Informatik und Wirtschaftsinformatik. Einige der Schwerpunkte sind Cloud Computing, Parallelisierung und In-Memory Technologien. In diesem Technischen Bericht werden die Ergebnisse der Forschungsprojekte des Jahres 2017 vorgestellt. Ausgewählte Projekte stellten ihre Ergebnisse am 25. April und 15. November 2017 im Rahmen der Future SOC Lab Tag Veranstaltungen vor. T3 - Technische Berichte des Hasso-Plattner-Instituts für Digital Engineering an der Universität Potsdam - 130 KW - Future SOC Lab KW - research projects KW - multicore architectures KW - In-Memory technology KW - cloud computing KW - machine learning KW - artifical intelligence KW - Future SOC Lab KW - Forschungsprojekte KW - Multicore Architekturen KW - In-Memory Technologie KW - Cloud Computing KW - maschinelles Lernen KW - Künstliche Intelligenz Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-433100 SN - 978-3-86956-475-3 SN - 1613-5652 SN - 2191-1665 IS - 130 PB - Universitätsverlag Potsdam CY - Potsdam ER -