TY  - JOUR
A1  - Dengler, Jürgen
A1  - Wagner, Viktoria
A1  - Dembicz, Iwona
A1  - Garcia-Mijangos, Itziar
A1  - Naqinezhad, Alireza
A1  - Boch, Steffen
A1  - Chiarucci, Alessandro
A1  - Conradi, Timo
A1  - Filibeck, Goffredo
A1  - Guarino, Riccardo
A1  - Janisova, Monika
A1  - Steinbauer, Manuel J.
A1  - Acic, Svetlana
A1  - Acosta, Alicia T. R.
A1  - Akasaka, Munemitsu
A1  - Allers, Marc-Andre
A1  - Apostolova, Iva
A1  - Axmanova, Irena
A1  - Bakan, Branko
A1  - Baranova, Alina
A1  - Bardy-Durchhalter, Manfred
A1  - Bartha, Sandor
A1  - Baumann, Esther
A1  - Becker, Thomas
A1  - Becker, Ute
A1  - Belonovskaya, Elena
A1  - Bengtsson, Karin
A1  - Benito Alonso, Jose Luis
A1  - Berastegi, Asun
A1  - Bergamini, Ariel
A1  - Bonini, Ilaria
A1  - Bruun, Hans Henrik
A1  - Budzhak, Vasyl
A1  - Bueno, Alvaro
A1  - Antonio Campos, Juan
A1  - Cancellieri, Laura
A1  - Carboni, Marta
A1  - Chocarro, Cristina
A1  - Conti, Luisa
A1  - Czarniecka-Wiera, Marta
A1  - De Frenne, Pieter
A1  - Deak, Balazs
A1  - Didukh, Yakiv P.
A1  - Diekmann, Martin
A1  - Dolnik, Christian
A1  - Dupre, Cecilia
A1  - Ecker, Klaus
A1  - Ermakov, Nikolai
A1  - Erschbamer, Brigitta
A1  - Escudero, Adrian
A1  - Etayo, Javier
A1  - Fajmonova, Zuzana
A1  - Felde, Vivian A.
A1  - Fernandez Calzado, Maria Rosa
A1  - Finckh, Manfred
A1  - Fotiadis, Georgios
A1  - Fracchiolla, Mariano
A1  - Ganeva, Anna
A1  - Garcia-Magro, Daniel
A1  - Gavilan, Rosario G.
A1  - Germany, Markus
A1  - Giladi, Itamar
A1  - Gillet, Francois
A1  - Giusso del Galdo, Gian Pietro
A1  - Gonzalez, Jose M.
A1  - Grytnes, John-Arvid
A1  - Hajek, Michal
A1  - Hajkova, Petra
A1  - Helm, Aveliina
A1  - Herrera, Mercedes
A1  - Hettenbergerova, Eva
A1  - Hobohm, Carsten
A1  - Huellbusch, Elisabeth M.
A1  - Ingerpuu, Nele
A1  - Jandt, Ute
A1  - Jeltsch, Florian
A1  - Jensen, Kai
A1  - Jentsch, Anke
A1  - Jeschke, Michael
A1  - Jimenez-Alfaro, Borja
A1  - Kacki, Zygmunt
A1  - Kakinuma, Kaoru
A1  - Kapfer, Jutta
A1  - Kavgaci, Ali
A1  - Kelemen, Andras
A1  - Kiehl, Kathrin
A1  - Koyama, Asuka
A1  - Koyanagi, Tomoyo F.
A1  - Kozub, Lukasz
A1  - Kuzemko, Anna
A1  - Kyrkjeeide, Magni Olsen
A1  - Landi, Sara
A1  - Langer, Nancy
A1  - Lastrucci, Lorenzo
A1  - Lazzaro, Lorenzo
A1  - Lelli, Chiara
A1  - Leps, Jan
A1  - Loebel, Swantje
A1  - Luzuriaga, Arantzazu L.
A1  - Maccherini, Simona
A1  - Magnes, Martin
A1  - Malicki, Marek
A1  - Marceno, Corrado
A1  - Mardari, Constantin
A1  - Mauchamp, Leslie
A1  - May, Felix
A1  - Michelsen, Ottar
A1  - Mesa, Joaquin Molero
A1  - Molnar, Zsolt
A1  - Moysiyenko, Ivan Y.
A1  - Nakaga, Yuko K.
A1  - Natcheva, Rayna
A1  - Noroozi, Jalil
A1  - Pakeman, Robin J.
A1  - Palpurina, Salza
A1  - Partel, Meelis
A1  - Paetsch, Ricarda
A1  - Pauli, Harald
A1  - Pedashenko, Hristo
A1  - Peet, Robert K.
A1  - Pielech, Remigiusz
A1  - Pipenbaher, Natasa
A1  - Pirini, Chrisoula
A1  - Pleskova, Zuzana
A1  - Polyakova, Mariya A.
A1  - Prentice, Honor C.
A1  - Reinecke, Jennifer
A1  - Reitalu, Triin
A1  - Pilar Rodriguez-Rojo, Maria
A1  - Rolecek, Jan
A1  - Ronkin, Vladimir
A1  - Rosati, Leonardo
A1  - Rosen, Ejvind
A1  - Ruprecht, Eszter
A1  - Rusina, Solvita
A1  - Sabovljevic, Marko
A1  - Maria Sanchez, Ana
A1  - Savchenko, Galina
A1  - Schuhmacher, Oliver
A1  - Skornik, Sonja
A1  - Sperandii, Marta Gaia
A1  - Staniaszek-Kik, Monika
A1  - Stevanovic-Dajic, Zora
A1  - Stock, Marin
A1  - Suchrow, Sigrid
A1  - Sutcliffe, Laura M. E.
A1  - Swacha, Grzegorz
A1  - Sykes, Martin
A1  - Szabo, Anna
A1  - Talebi, Amir
A1  - Tanase, Catalin
A1  - Terzi, Massimo
A1  - Tolgyesi, Csaba
A1  - Torca, Marta
A1  - Torok, Peter
A1  - Tothmeresz, Bela
A1  - Tsarevskaya, Nadezda
A1  - Tsiripidis, Ioannis
A1  - Tzonev, Rossen
A1  - Ushimaru, Atushi
A1  - Valko, Orsolya
A1  - van der Maarel, Eddy
A1  - Vanneste, Thomas
A1  - Vashenyak, Iuliia
A1  - Vassilev, Kiril
A1  - Viciani, Daniele
A1  - Villar, Luis
A1  - Virtanen, Risto
A1  - Kosic, Ivana Vitasovic
A1  - Wang, Yun
A1  - Weiser, Frank
A1  - Went, Julia
A1  - Wesche, Karsten
A1  - White, Hannah
A1  - Winkler, Manuela
A1  - Zaniewski, Piotr T.
A1  - Zhang, Hui
A1  - Ziv, Yaron
A1  - Znamenskiy, Sergey
A1  - Biurrun, Idoia
T1  - GrassPlot - a database of multi-scale plant diversity in Palaearctic grasslands
JF  - Phytocoenologia
N2  - GrassPlot is a collaborative vegetation-plot database organised by the Eurasian Dry Grassland Group (EDGG) and listed in the Global Index of Vegetation-Plot Databases (GIVD ID EU-00-003). GrassPlot collects plot records (releves) from grasslands and other open habitats of the Palaearctic biogeographic realm. It focuses on precisely delimited plots of eight standard grain sizes (0.0001; 0.001;... 1,000 m(2)) and on nested-plot series with at least four different grain sizes. The usage of GrassPlot is regulated through Bylaws that intend to balance the interests of data contributors and data users. The current version (v. 1.00) contains data for approximately 170,000 plots of different sizes and 2,800 nested-plot series. The key components are richness data and metadata. However, most included datasets also encompass compositional data. About 14,000 plots have near-complete records of terricolous bryophytes and lichens in addition to vascular plants. At present, GrassPlot contains data from 36 countries throughout the Palaearctic, spread across elevational gradients and major grassland types. GrassPlot with its multi-scale and multi-taxon focus complements the larger international vegetationplot databases, such as the European Vegetation Archive (EVA) and the global database " sPlot". Its main aim is to facilitate studies on the scale-and taxon-dependency of biodiversity patterns and drivers along macroecological gradients. GrassPlot is a dynamic database and will expand through new data collection coordinated by the elected Governing Board. We invite researchers with suitable data to join GrassPlot. Researchers with project ideas addressable with GrassPlot data are welcome to submit proposals to the Governing Board.
KW  - biodiversity
KW  - European Vegetation Archive (EVA)
KW  - Eurasian Dry Grassland Group (EDGG)
KW  - grassland vegetation
KW  - GrassPlot
KW  - macroecology
KW  - multi-taxon
KW  - nested plot
KW  - scale-dependence
KW  - species-area relationship (SAR)
KW  - sPlot
KW  - vegetation-plot database
Y1  - 2018
U6  - https://doi.org/10.1127/phyto/2018/0267
SN  - 0340-269X
VL  - 48
IS  - 3
SP  - 331
EP  - 347
PB  - Cramer
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Corsten, Sabine
A1  - Günther, Thomas
A1  - Nieslony, Julia
A1  - Flöther, Manfred
A1  - Rott, Anke
A1  - Schöppe, Doreen
A1  - Kösterke-Buchardt, Antje
A1  - Machleb, Franziska
A1  - Purat, Patricia
A1  - Euler, Harald A.
A1  - Breitenstein, Sarah
A1  - Düsterhöft, Stefanie
A1  - Posse, Dorothea
A1  - Topaj, Nathalie
A1  - Golcher, Felix
A1  - Gagarina, Natalʹja Vladimirovna
A1  - Stegenwallner-Schütz, Maja Henny Katherine
A1  - Lassotta, Romy
A1  - Ferchland, Lisa
A1  - Adani, Flavia
A1  - Wotschack, Christiane
A1  - Klassert, Annegret
A1  - Festman, Julia
A1  - Schumacher, Rebecca
A1  - Burchert, Frank
A1  - Ablinger, Irene
A1  - Buttler, Rahel
A1  - Frank, Luis
A1  - Stadie, Nicole
A1  - Weiland, Linda
A1  - Netzebandt, Jonka
A1  - Frank, Ulrike
A1  - Bykova, Ksenia
A1  - Loppnow, Anna
A1  - Huckabee, Maggie-Lee
A1  - Krusche, Lisa
ED  - Fritzsche, Tom
ED  - Yetim, Özlem
ED  - Otto, Constanze
ED  - Adelt, Anne
T1  - Spektrum Patholinguistik Band 9. Schwerpunktthema: Lauter Laute: Phonologische Verarbeitung und Lautwahrnehmung in der Sprachtherapie
T2  - Spektrum Patholinguistik
N2  - Das 9. Herbsttreffen Patholinguistik mit dem Schwerpunktthema "Lauter Laute: Phonologische Verarbeitung und Lautwahrnehmung in der Sprachtherapie" fand am 14.11.2015 in Potsdam statt. Das Herbsttreffen wird seit 2007 jährlich vom Verband für Patholinguistik e.V. (vpl) durchgeführt. Der vorliegende Tagungsband beinhaltet die vier Hauptvorträge zum Schwerpunktthema, die drei Kurzvorträge aus dem Spektrum Patholinguisitk sowie die Beiträge der Posterpräsentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis.
N2  - The Ninth Autumn Meeting Patholinguistics ('Herbsttreffen Patholinguistik') with its main topic "Lots of sounds: Phonological processing and sound perception in speech/language therapy" took place in Potsdam on November 14 2015. This annual meeting has been organized since 2007 by the Association for Patholinguistics (Verband für Patholinguistik e.V./vpl). The present proceedings contain the four keynote talks on the main topic, the three short talks from the series 'Spectrum Patholinguistics', as well as the contributions of the poster session from all areas of speech/language therapy research and practice.
T3  - Spektrum Patholinguistik - 9 
KW  - Patholinguistik
KW  - Sprachtherapie
KW  - Phonologische Verarbeitung
KW  - Lautwahrnehmung
KW  - Sprachverarbeitung
KW  - patholinguistics
KW  - speech/language therapy
KW  - phonological processing
KW  - sound perception
KW  - language processing
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-96653
SN  - 978-3-86956-385-5
SN  - 1866-9085
SN  - 1866-9433
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Buttler, Rahel
A1  - Frank, Luis
A1  - Stadie, Nicole
T1  - Studium trifft Praxis
BT  - Evidenzbasierung bei der Behandlung von erworbenen Sprachstörungen im externen Praktikum
JF  - Spektrum Patholinguistik Band 9. Schwerpunktthema: Lauter Laute: Phonologische Verarbeitung und Lautwahrnehmung in der Sprachtherapie
N2  - 1. Einleitung, 2. Informationen zu Probanden, 3. Informationen zur Behandlung, 4. Informationen zur Evaluation, 5. Fazit, 6. Literatur
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-99106
SN  - 1866-9085
SN  - 1866-9433
IS  - 9
SP  - 215
EP  - 218
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Horikoshi, Momoko
A1  - Yaghootkar, Hanieh
A1  - Mook-Kanamori, Dennis O.
A1  - Sovio, Ulla
A1  - Taal, H. Rob
A1  - Hennig, Branwen J.
A1  - Bradfield, Jonathan P.
A1  - St Pourcain, Beate
A1  - Evans, David M.
A1  - Charoen, Pimphen
A1  - Kaakinen, Marika
A1  - Cousminer, Diana L.
A1  - Lehtimaki, Terho
A1  - Kreiner-Moller, Eskil
A1  - Warrington, Nicole M.
A1  - Bustamante, Mariona
A1  - Feenstra, Bjarke
A1  - Berry, Diane J.
A1  - Thiering, Elisabeth
A1  - Pfab, Thiemo
A1  - Barton, Sheila J.
A1  - Shields, Beverley M.
A1  - Kerkhof, Marjan
A1  - van Leeuwen, Elisabeth M.
A1  - Fulford, Anthony J.
A1  - Kutalik, Zoltan
A1  - Zhao, Jing Hua
A1  - den Hoed, Marcel
A1  - Mahajan, Anubha
A1  - Lindi, Virpi
A1  - Goh, Liang-Kee
A1  - Hottenga, Jouke-Jan
A1  - Wu, Ying
A1  - Raitakari, Olli T.
A1  - Harder, Marie N.
A1  - Meirhaeghe, Aline
A1  - Ntalla, Ioanna
A1  - Salem, Rany M.
A1  - Jameson, Karen A.
A1  - Zhou, Kaixin
A1  - Monies, Dorota M.
A1  - Lagou, Vasiliki
A1  - Kirin, Mirna
A1  - Heikkinen, Jani
A1  - Adair, Linda S.
A1  - Alkuraya, Fowzan S.
A1  - Al-Odaib, Ali
A1  - Amouyel, Philippe
A1  - Andersson, Ehm Astrid
A1  - Bennett, Amanda J.
A1  - Blakemore, Alexandra I. F.
A1  - Buxton, Jessica L.
A1  - Dallongeville, Jean
A1  - Das, Shikta
A1  - de Geus, Eco J. C.
A1  - Estivill, Xavier
A1  - Flexeder, Claudia
A1  - Froguel, Philippe
A1  - Geller, Frank
A1  - Godfrey, Keith M.
A1  - Gottrand, Frederic
A1  - Groves, Christopher J.
A1  - Hansen, Torben
A1  - Hirschhorn, Joel N.
A1  - Hofman, Albert
A1  - Hollegaard, Mads V.
A1  - Hougaard, David M.
A1  - Hyppoenen, Elina
A1  - Inskip, Hazel M.
A1  - Isaacs, Aaron
A1  - Jorgensen, Torben
A1  - Kanaka-Gantenbein, Christina
A1  - Kemp, John P.
A1  - Kiess, Wieland
A1  - Kilpelainen, Tuomas O.
A1  - Klopp, Norman
A1  - Knight, Bridget A.
A1  - Kuzawa, Christopher W.
A1  - McMahon, George
A1  - Newnham, John P.
A1  - Niinikoski, Harri
A1  - Oostra, Ben A.
A1  - Pedersen, Louise
A1  - Postma, Dirkje S.
A1  - Ring, Susan M.
A1  - Rivadeneira, Fernando
A1  - Robertson, Neil R.
A1  - Sebert, Sylvain
A1  - Simell, Olli
A1  - Slowinski, Torsten
A1  - Tiesler, Carla M. T.
A1  - Toenjes, Anke
A1  - Vaag, Allan
A1  - Viikari, Jorma S.
A1  - Vink, Jacqueline M.
A1  - Vissing, Nadja Hawwa
A1  - Wareham, Nicholas J.
A1  - Willemsen, Gonneke
A1  - Witte, Daniel R.
A1  - Zhang, Haitao
A1  - Zhao, Jianhua
A1  - Wilson, James F.
A1  - Stumvoll, Michael
A1  - Prentice, Andrew M.
A1  - Meyer, Brian F.
A1  - Pearson, Ewan R.
A1  - Boreham, Colin A. G.
A1  - Cooper, Cyrus
A1  - Gillman, Matthew W.
A1  - Dedoussis, George V.
A1  - Moreno, Luis A.
A1  - Pedersen, Oluf
A1  - Saarinen, Maiju
A1  - Mohlke, Karen L.
A1  - Boomsma, Dorret I.
A1  - Saw, Seang-Mei
A1  - Lakka, Timo A.
A1  - Koerner, Antje
A1  - Loos, Ruth J. F.
A1  - Ong, Ken K.
A1  - Vollenweider, Peter
A1  - van Duijn, Cornelia M.
A1  - Koppelman, Gerard H.
A1  - Hattersley, Andrew T.
A1  - Holloway, John W.
A1  - Hocher, Berthold
A1  - Heinrich, Joachim
A1  - Power, Chris
A1  - Melbye, Mads
A1  - Guxens, Monica
A1  - Pennell, Craig E.
A1  - Bonnelykke, Klaus
A1  - Bisgaard, Hans
A1  - Eriksson, Johan G.
A1  - Widen, Elisabeth
A1  - Hakonarson, Hakon
A1  - Uitterlinden, Andre G.
A1  - Pouta, Anneli
A1  - Lawlor, Debbie A.
A1  - Smith, George Davey
A1  - Frayling, Timothy M.
A1  - McCarthy, Mark I.
A1  - Grant, Struan F. A.
A1  - Jaddoe, Vincent W. V.
A1  - Jarvelin, Marjo-Riitta
A1  - Timpson, Nicholas J.
A1  - Prokopenko, Inga
A1  - Freathy, Rachel M.
T1  - New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
JF  - Nature genetics
N2  - Birth weight within the normal range is associated with a variety of adult-onset diseases, but the mechanisms behind these associations are poorly understood(1). Previous genome-wide association studies of birth weight identified a variant in the ADCY5 gene associated both with birth weight and type 2 diabetes and a second variant, near CCNL1, with no obvious link to adult traits(2). In an expanded genome-wide association metaanalysis and follow-up study of birth weight (of up to 69,308 individuals of European descent from 43 studies), we have now extended the number of loci associated at genome-wide significance to 7, accounting for a similar proportion of variance as maternal smoking. Five of the loci are known to be associated with other phenotypes: ADCY5 and CDKAL1 with type 2 diabetes, ADRB1 with adult blood pressure and HMGA2 and LCORL with adult height. Our findings highlight genetic links between fetal growth and postnatal growth and metabolism.
Y1  - 2013
U6  - https://doi.org/10.1038/ng.2477
SN  - 1061-4036
VL  - 45
IS  - 1
SP  - 76
EP  - U115
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - JOUR
A1  - Matos, Catarina
A1  - Silveira, Graca
A1  - Matias, Luis
A1  - Caldeira, Rita
A1  - Ribeiro, M. Luisa
A1  - Dias, Nuno A.
A1  - Krüger, Frank
A1  - Bento dos Santos, Telmo
T1  - Upper crustal structure of Madeira Island revealed from ambient noise tomography
JF  - Journal of volcanology and geothermal research
N2  - We present the first image of the Madeira upper crustal structure, using ambient seismic noise tomography. 16 months of ambient noise, recorded in a dense network of 26 seismometers deployed across Madeira, allowed reconstructing Rayleigh wave Green's functions between receivers. Dispersion analysis was performed in the short period band from 1.0 to 4.0 s. Group velocity measurements were regionalized to obtain 20 tomographic images, with a lateral resolution of 2.0 km in central Madeira. Afterwards, the dispersion curves, extracted from each cell of the 2D group velocity maps, were inverted as a function of depth to obtain a 3D shear wave velocity model of the upper crust, from the surface to a depth of 2.0 km. The obtained 3D velocity model reveals features throughout the island that correlates well with surface geology and island evolution. (C) 2015 Elsevier B.V. All rights reserved.
KW  - Madeira island
KW  - Volcanic rift zone
KW  - Crustal structure
KW  - Ambient noise tomography
Y1  - 2015
U6  - https://doi.org/10.1016/j.jvolgeores.2015.03.017
SN  - 0377-0273
SN  - 1872-6097
VL  - 298
SP  - 136
EP  - 145
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Pajoro, Alice
A1  - Madrigal, Pedro
A1  - Muino, Jose M.
A1  - Tomas Matus, Jose
A1  - Jin, Jian
A1  - Mecchia, Martin A.
A1  - Debernardi, Juan M.
A1  - Palatnik, Javier F.
A1  - Balazadeh, Salma
A1  - Arif, Muhammad
A1  - Wellmer, Frank
A1  - Krajewski, Pawel
A1  - Riechmann, Jose-Luis
A1  - Angenent, Gerco C.
A1  - Kaufmann, Kerstin
T1  - Dynamics of chromatin accessibility and gene regulation by MADS-domain transcription factors in flower development
JF  - Genome biology : biology for the post-genomic era
N2  - Background: Development of eukaryotic organisms is controlled by transcription factors that trigger specific and global changes in gene expression programs. In plants, MADS-domain transcription factors act as master regulators of developmental switches and organ specification. However, the mechanisms by which these factors dynamically regulate the expression of their target genes at different developmental stages are still poorly understood.
 Results: We characterized the relationship of chromatin accessibility, gene expression, and DNA binding of two MADS-domain proteins at different stages of Arabidopsis flower development. Dynamic changes in APETALA1 and SEPALLATA3 DNA binding correlated with changes in gene expression, and many of the target genes could be associated with the developmental stage in which they are transcriptionally controlled. We also observe dynamic changes in chromatin accessibility during flower development. Remarkably, DNA binding of APETALA1 and SEPALLATA3 is largely independent of the accessibility status of their binding regions and it can precede increases in DNA accessibility. These results suggest that APETALA1 and SEPALLATA3 may modulate chromatin accessibility, thereby facilitating access of other transcriptional regulators to their target genes.
 Conclusions: Our findings indicate that different homeotic factors regulate partly overlapping, yet also distinctive sets of target genes in a partly stage-specific fashion. By combining the information from DNA-binding and gene expression data, we are able to propose models of stage-specific regulatory interactions, thereby addressing dynamics of regulatory networks throughout flower development. Furthermore, MADS-domain TFs may regulate gene expression by alternative strategies, one of which is modulation of chromatin accessibility.
KW  - Flower Development
KW  - Floral Organ
KW  - Floral Meristem
KW  - Chromatin Accessibility
KW  - Growth Regulate Factor
Y1  - 2014
U6  - https://doi.org/10.1186/gb-2014-15-3-r41
SN  - 1465-6906
SN  - 1474-760X
VL  - 15
PB  - BioMed Central
CY  - London
ER  - 
TY  - GEN
A1  - Pajoro, Alice
A1  - Madrigal, Pedro
A1  - Muiño, Jose M.
A1  - Matus, José Tomás
A1  - Jin, Jian
A1  - Mecchia, Martin A.
A1  - Debernardi, Juan M.
A1  - Palatnik, Javier F.
A1  - Balazadeh, Salma
A1  - Arif, Muhammad
A1  - Ó’Maoiléidigh, Diarmuid S.
A1  - Wellmer, Frank
A1  - Krajewski, Pawel
A1  - Riechmann, José-Luis
A1  - Angenent, Gerco C.
A1  - Kaufmann, Kerstin
T1  - Dynamics of chromatin accessibility and gene regulation by MADS-domain transcription factors in flower development
T2  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Background: Development of eukaryotic organisms is controlled by transcription factors that trigger specific and global changes in gene expression programs. In plants, MADS-domain transcription factors act as master regulators of developmental switches and organ specification. However, the mechanisms by which these factors dynamically regulate the expression of their target genes at different developmental stages are still poorly understood.

Results: We characterized the relationship of chromatin accessibility, gene expression, and DNA binding of two MADS-domain proteins at different stages of Arabidopsis flower development. Dynamic changes in APETALA1 and SEPALLATA3 DNA binding correlated with changes in gene expression, and many of the target genes could be associated with the developmental stage in which they are transcriptionally controlled. We also observe dynamic changes in chromatin accessibility during flower development. Remarkably, DNA binding of APETALA1 and SEPALLATA3 is largely independent of the accessibility status of their binding regions and it can precede increases in DNA accessibility. These results suggest that APETALA1 and SEPALLATA3 may modulate chromatin accessibility, thereby facilitating access of other transcriptional regulators to their target genes.

Conclusions: Our findings indicate that different homeotic factors regulate partly overlapping, yet also distinctive sets of target genes in a partly stage-specific fashion. By combining the information from DNA-binding and gene expression data, we are able to propose models of stage-specific regulatory interactions, thereby addressing dynamics of regulatory networks throughout flower development. Furthermore, MADS-domain TFs may regulate gene expression by alternative strategies, one of which is modulation of chromatin accessibility.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1327 
KW  - flower development
KW  - floral organ
KW  - floral meristem
KW  - chromatin accessibility
KW  - growth regulate factor
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-431139
SN  - 1866-8372
VL  - 15
ER  - 
TY  - JOUR
A1  - Schulze-Makuch, Dirk
A1  - Wagner, Dirk
A1  - Kounaves, Samuel P.
A1  - Mangelsdorf, Kai
A1  - Devine, Kevin G.
A1  - de Vera, Jean-Pierre
A1  - Schmitt-Kopplin, Philippe
A1  - Grossart, Hans-Peter
A1  - Parro, Victor
A1  - Kaupenjohann, Martin
A1  - Galy, Albert
A1  - Schneider, Beate
A1  - Airo, Alessandro
A1  - Froesler, Jan
A1  - Davila, Alfonso F.
A1  - Arens, Felix L.
A1  - Caceres, Luis
A1  - Cornejo, Francisco Solis
A1  - Carrizo, Daniel
A1  - Dartnell, Lewis
A1  - DiRuggiero, Jocelyne
A1  - Flury, Markus
A1  - Ganzert, Lars
A1  - Gessner, Mark O.
A1  - Grathwohl, Peter
A1  - Guan, Lisa
A1  - Heinz, Jacob
A1  - Hess, Matthias
A1  - Keppler, Frank
A1  - Maus, Deborah
A1  - McKay, Christopher P.
A1  - Meckenstock, Rainer U.
A1  - Montgomery, Wren
A1  - Oberlin, Elizabeth A.
A1  - Probst, Alexander J.
A1  - Saenz, Johan S.
A1  - Sattler, Tobias
A1  - Schirmack, Janosch
A1  - Sephton, Mark A.
A1  - Schloter, Michael
A1  - Uhl, Jenny
A1  - Valenzuela, Bernardita
A1  - Vestergaard, Gisle
A1  - Woermer, Lars
A1  - Zamorano, Pedro
T1  - Transitory microbial habitat in the hyperarid Atacama Desert
JF  - Proceedings of the National Academy of Sciences of the United States of America
KW  - habitat
KW  - aridity
KW  - microbial activity
KW  - biomarker
KW  - Mars
Y1  - 2018
U6  - https://doi.org/10.1073/pnas.1714341115
SN  - 0027-8424
VL  - 115
IS  - 11
SP  - 2670
EP  - 2675
PB  - National Acad. of Sciences
CY  - Washington
ER  - 
TY  - BOOK
A1  - Rana, Kaushik
A1  - Mohapatra, Durga Prasad
A1  - Sidorova, Julia
A1  - Lundberg, Lars
A1  - Sköld, Lars
A1  - Lopes Grim, Luís Fernando
A1  - Sampaio Gradvohl, André Leon
A1  - Cremerius, Jonas
A1  - Siegert, Simon
A1  - Weltzien, Anton von
A1  - Baldi, Annika
A1  - Klessascheck, Finn
A1  - Kalancha, Svitlana
A1  - Lichtenstein, Tom
A1  - Shaabani, Nuhad
A1  - Meinel, Christoph
A1  - Friedrich, Tobias
A1  - Lenzner, Pascal
A1  - Schumann, David
A1  - Wiese, Ingmar
A1  - Sarna, Nicole
A1  - Wiese, Lena
A1  - Tashkandi, Araek Sami
A1  - van der Walt, Estée
A1  - Eloff, Jan H. P.
A1  - Schmidt, Christopher
A1  - Hügle, Johannes
A1  - Horschig, Siegfried
A1  - Uflacker, Matthias
A1  - Najafi, Pejman
A1  - Sapegin, Andrey
A1  - Cheng, Feng
A1  - Stojanovic, Dragan
A1  - Stojnev Ilić, Aleksandra
A1  - Djordjevic, Igor
A1  - Stojanovic, Natalija
A1  - Predic, Bratislav
A1  - González-Jiménez, Mario
A1  - de Lara, Juan
A1  - Mischkewitz, Sven
A1  - Kainz, Bernhard
A1  - van Hoorn, André
A1  - Ferme, Vincenzo
A1  - Schulz, Henning
A1  - Knigge, Marlene
A1  - Hecht, Sonja
A1  - Prifti, Loina
A1  - Krcmar, Helmut
A1  - Fabian, Benjamin
A1  - Ermakova, Tatiana
A1  - Kelkel, Stefan
A1  - Baumann, Annika
A1  - Morgenstern, Laura
A1  - Plauth, Max
A1  - Eberhard, Felix
A1  - Wolff, Felix
A1  - Polze, Andreas
A1  - Cech, Tim
A1  - Danz, Noel
A1  - Noack, Nele Sina
A1  - Pirl, Lukas
A1  - Beilharz, Jossekin Jakob
A1  - De Oliveira, Roberto C. L.
A1  - Soares, Fábio Mendes
A1  - Juiz, Carlos
A1  - Bermejo, Belen
A1  - Mühle, Alexander
A1  - Grüner, Andreas
A1  - Saxena, Vageesh
A1  - Gayvoronskaya, Tatiana
A1  - Weyand, Christopher
A1  - Krause, Mirko
A1  - Frank, Markus
A1  - Bischoff, Sebastian
A1  - Behrens, Freya
A1  - Rückin, Julius
A1  - Ziegler, Adrian
A1  - Vogel, Thomas
A1  - Tran, Chinh
A1  - Moser, Irene
A1  - Grunske, Lars
A1  - Szárnyas, Gábor
A1  - Marton, József
A1  - Maginecz, János
A1  - Varró, Dániel
A1  - Antal, János Benjamin
ED  - Meinel, Christoph
ED  - Polze, Andreas
ED  - Beins, Karsten
ED  - Strotmann, Rolf
ED  - Seibold, Ulrich
ED  - Rödszus, Kurt
ED  - Müller, Jürgen
T1  - HPI Future SOC Lab – Proceedings 2018
N2  - The “HPI Future SOC Lab” is a cooperation of the Hasso Plattner Institute (HPI) and industry partners. Its mission is to enable and promote exchange and interaction between the research community and the industry partners.
  The HPI Future SOC Lab provides researchers with free of charge access to a complete infrastructure of state of the art hard and software. This infrastructure includes components, which might be too expensive for an ordinary research environment, such as servers with up to 64 cores and 2 TB main memory. The offerings address researchers particularly from but not limited to the areas of computer science and business information systems. Main areas of research include cloud computing, parallelization, and In-Memory technologies.
  This technical report presents results of research projects executed in 2018. Selected projects have presented their results on April 17th and November 14th 2017 at the Future SOC Lab Day events.
N2  - Das Future SOC Lab am HPI ist eine Kooperation des Hasso-Plattner-Instituts mit verschiedenen Industriepartnern. Seine Aufgabe ist die Ermöglichung und Förderung des Austausches zwischen Forschungsgemeinschaft und Industrie.
  Am Lab wird interessierten Wissenschaftler:innen eine Infrastruktur von neuester Hard- und Software kostenfrei für Forschungszwecke zur Verfügung gestellt. Dazu zählen Systeme, die im normalen Hochschulbereich in der Regel nicht zu finanzieren wären, bspw. Server mit bis zu 64 Cores und 2 TB Hauptspeicher. Diese Angebote richten sich insbesondere an Wissenschaftler:innen in den Gebieten Informatik und Wirtschaftsinformatik. Einige der Schwerpunkte sind Cloud Computing, Parallelisierung und In-Memory Technologien. 
  In diesem Technischen Bericht werden die Ergebnisse der Forschungsprojekte des Jahres 2018 vorgestellt.  Ausgewählte Projekte stellten ihre Ergebnisse am 17. April und 14. November 2018 im Rahmen des Future SOC Lab Tags vor.
T3  - Technische Berichte des Hasso-Plattner-Instituts für Digital Engineering an der Universität Potsdam - 151 
KW  - Future SOC Lab
KW  - research projects
KW  - multicore architectures
KW  - in-memory technology
KW  - cloud computing
KW  - machine learning
KW  - artifical intelligence
KW  - Future SOC Lab
KW  - Forschungsprojekte
KW  - Multicore Architekturen
KW  - In-Memory Technologie
KW  - Cloud Computing
KW  - maschinelles Lernen
KW  - künstliche Intelligenz
Y1  - 2022
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-563712
SN  - 978-3-86956-547-7
SN  - 1613-5652
SN  - 2191-1665
IS  - 151
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  -