TY - JOUR A1 - Pan, Xiaohui A1 - Wang, Weishi A1 - Liu, Tie A1 - Huang, Yue A1 - De Maeyer, Philippe A1 - Guo, Chenyu A1 - Ling, Yunan A1 - Akmalov, Shamshodbek T1 - Quantitative detection and attribution of groundwater level variations in the Amu Darya Delta JF - Water N2 - In the past few decades, the shrinkage of the Aral Sea is one of the biggest ecological catastrophes caused by human activity. To quantify the joint impact of both human activities and climate change on groundwater, the spatiotemporal groundwater dynamic characteristics in the Amu Darya Delta of the Aral Sea from 1999 to 2017 were analyzed, using the groundwater level, climate conditions, remote sensing data, and irrigation information. Statistics analysis was adopted to analyze the trend of groundwater variation, including intensity, periodicity, spatial structure, while the Pearson correlation analysis and principal component analysis (PCA) were used to quantify the impact of climate change and human activities on the variabilities of the groundwater level. Results reveal that the local groundwater dynamic has varied considerably. From 1999 to 2002, the groundwater level dropped from -189 cm to -350 cm. Until 2017, the groundwater level rose back to -211 cm with fluctuation. Seasonally, the fluctuation period of groundwater level and irrigation water was similar, both were about 18 months. Spatially, the groundwater level kept stable within the irrigation area and bare land but fluctuated drastically around the irrigation area. The Pearson correlation analysis reveals that the dynamic of the groundwater level is closely related to irrigation activity within the irrigation area (Nukus: -0.583), while for the place adjacent to the Aral Sea, the groundwater level is closely related to the Large Aral Sea water level (Muynak: 0.355). The results of PCA showed that the cumulative contribution rate of the first three components exceeds 85%. The study reveals that human activities have a great impact on groundwater, effective management, and the development of water resources in arid areas is an essential prerequisite for ecological protection. KW - groundwater level variation KW - climate change KW - human activities KW - statistical analysis KW - Amu Darya Delta Y1 - 2020 U6 - https://doi.org/10.3390/w12102869 SN - 2073-4441 VL - 12 IS - 10 PB - MDPI CY - Basel ER - TY - JOUR A1 - Li, Jian A1 - Chen, You-Peng A1 - Wang, Zi-Neng A1 - Liu, Tie-Bin A1 - Chen, Dan A1 - Dong, Yun-Peng A1 - Hocher, Berthold T1 - A functional fetal HSD11B2[CA]n microsatellite polymorphism is associated with maternal serum cortisol concentrations in pregnant women JF - Kidney & blood pressure research : official organ of the Gesellschaft für Nephrologie N2 - Background/Aims: Cortisol plays an important role during pregnancy. It controls maternal glucose metabolism and fetal development. Cortisol metabolism is partially controlled by the 11b-HSD2. This enzyme is expressed in the kidney and human placenta. The activity of the enzyme is partially controlled by functional polymorphisms: the HSD11B2[CA]n microsatellite polymorphism. The impact of this functional gene polymorphism on cortisol metabolism and potential effects on the newborn's is unknown so far. Methods: In the current prospective birth cohort study in southern Asia, we analyzed the association of the HSD11B2[CA]n microsatellite polymorphisms in 187 mothers and their newborn's on maternal and newborn's serum cortisol concentrations. Results: Using multivariable regression analyses considering known confounding ( gestational age, newborn's gender, the labor uterine contraction states and the timing during the day of blood taking), we showed that the fetal HSD11B2[CA]n microsatellite polymorphisms in the first intron was related to maternal cortisol concentration ( R2=0.26, B=96.27, p=0.007), whereas as the newborn's cortisol concentrations were independent of fetal and maternal HSD11B2[CA] n microsatellite polymorphism. Conclusions: Our study showed for the first time that the fetal HSD11B2[CA]n microsatellite polymorphism of the HSD11B2 gene in healthy uncomplicated human pregnancy is associated with maternal cortisol concentration. This indicates that fetal genes controlling cortisol metabolism may affect maternal cortisol concentration and hence physiology in healthy pregnant women. KW - Pregnancy KW - Placenta KW - Cortisol vertical bar metabolism KW - 11 beta-hydroxysteroid dehydrogenase 2 KW - HSD11B2[CA]n polymorphism Y1 - 2013 U6 - https://doi.org/10.1159/000355761 SN - 1420-4096 SN - 1423-0143 VL - 38 IS - 1 SP - 132 EP - 141 PB - Karger CY - Basel ER - TY - JOUR A1 - Wang, Wei-shi A1 - Oswald, Sascha A1 - Gräff, Thomas A1 - Lensing, Hermann Josef A1 - Liu, Tie A1 - Strasser, Daniel A1 - Munz, Matthias T1 - Impact of river reconstruction on groundwater flow during bank filtration assessed by transient three-dimensional modelling of flow and heat transport JF - Hydrogeology journal : official journal of the International Association of Hydrogeologists N2 - Bank filtration (BF) is an established indirect water-treatment technology. The quality of water gained via BF depends on the subsurface capture zone, the mixing ratio (river water versus ambient groundwater), spatial and temporal distribution of subsurface travel times, and subsurface temperature patterns. Surface-water infiltration into the adjacent aquifer is determined by the local hydraulic gradient and riverbed permeability, which could be altered by natural clogging, scouring and artificial decolmation processes. The seasonal behaviour of a BF system in Germany, and its development during and about 6 months after decolmation (canal reconstruction), was observed with a long-term monitoring programme. To quantify the spatial and temporal variation in the BF system, a transient flow and heat transport model was implemented and two model scenarios, 'with' and 'without' canal reconstruction, were generated. Overall, the simulated water heads and temperatures matched those observed. Increased hydraulic connection between the canal and aquifer caused by the canal reconstruction led to an increase of similar to 23% in the already high share of BF water abstracted by the nearby waterworks. Subsurface travel-time distribution substantially shifted towards shorter travel times. Flow paths with travel times <200 days increased by similar to 10% and those with <300 days by 15%. Generally, the periodic temperature signal, and the summer and winter temperature extrema, increased and penetrated deeper into the aquifer. The joint hydrological and thermal effects caused by the canal reconstruction might increase the potential of biodegradable compounds to further penetrate into the aquifer, also by potentially affecting the redox zonation in the aquifer. KW - bank filtration KW - groundwater KW - surface-water relations KW - groundwater modelling Y1 - 2019 U6 - https://doi.org/10.1007/s10040-019-02063-3 SN - 1431-2174 SN - 1435-0157 VL - 28 IS - 2 SP - 723 EP - 743 PB - Springer CY - Berlin ; Heidelberg [u.a.] ER - TY - GEN A1 - Wang, Wei-shi A1 - Oswald, Sascha A1 - Gräff, Thomas A1 - Lensing, Hermann-Josef A1 - Liu, Tie A1 - Strasser, Daniel A1 - Munz, Matthias T1 - Correction: Impact of river reconstruction on groundwater flow during bank filtration assessed by transient three-dimensional modelling of flow and heat transport. - Hydrogeology Journal. - Berlin: Springer. - 28 (2020) , S. 723. - https://doi.org/10.1007/s10040-019-02063-3 T2 - Hydrogeology journal : official journal of the International Association of Hydrogeologists T2 - Erratum: Impact de la reconstruction d’une rivière sur l’écoulement des eaux souterraines via la filtration sur berge évalué par un modèle tridimensionnel en régime transitoire de l’écoulement et du transport de chaleur. - Berlin: Springer. - 28 (2020) , S. 723. - https://doi.org/10.1007/s10040-019-02063-3 T2 - Erratum: Impacto de la restauración de un río en el flujo de agua subterránea durante la filtración en las márgenes, evaluado mediante la modelización tridimensional transitoria del flujo y el transporte de calor. - Berlin: Springer. - 28 (2020) , S. 723. - https://doi.org/10.1007/s10040-019-02063-3 Y1 - 2020 U6 - https://doi.org/10.1007/s10040-020-02221-y SN - 1431-2174 SN - 1435-0157 VL - 28 IS - 7 SP - 2633 EP - 2634 PB - Springer CY - Berlin ; Heidelberg ; New York, NY ER -