TY - JOUR A1 - Hayer, Anna A1 - de Halleux, Veronique A1 - Köhler, Anna A1 - El-Garoughy, Abdel A1 - Meijer, E. W. A1 - Barbera, Joaquin A1 - Tant, Julien A1 - Levin, Jeremy A1 - Lehmann, Matthias A1 - Gierschner, Johannes A1 - Cornil, Jerome A1 - Geerts, Yves Henri T1 - Highly fluorescent crystalline and liquid crystalline columnar phases of pyrene-based structures N2 - A concept for highly ordered solid-state structures with bright fluorescence is proposed: liquid crystals based on tetraethynylpyrene chromophores, where the rigid core is functionalized with flexible, promesogenic alkoxy chains. The synthesis of this novel material is presented. The therniotropic properties are studied by means of differential scanning calorimetry (DSC), cross-polarized optical microscopy (POM), and X-ray diffraction. The mesogen possesses an enantiotropic Col(h) phase over a large temperature range before clearing. The material is highly fluorescent in solution and, most remarkably, in the condensed state, with a broad, strongly red shifted emission. Fluorescence quantum yields (Phi(F)) have been determined to be 70% in dichloromethane solution and 62% in the solid state. Concentration- and temperature-dependent absorption and emission studies as well as quantum-chemical calculations on isolated molecules and dimers are used to clarify the type of intermolecular interactions present as well as their influence on the fluorescence quantum yield and spectral properties of the material. The high luminescence efficiency in the solid state is ascribed to rotated chromophores, leading to an optically allowed lowest optical transition Y1 - 2006 UR - http://pubs.acs.org/journal/jpcbfk U6 - https://doi.org/10.1021/Jp0573689 SN - 1520-6106 ER - TY - JOUR A1 - Grießner, Matthias A1 - Broeker, Patrick A1 - Lehmann, André A1 - Ehrentreich-Förster, Eva A1 - Bier, Frank Fabian T1 - Detection of angiotensin II type 1 receptor ligands by a cell-based assay N2 - This work describes a cell-based assay that does not depend on radioactivity or laboratory animals for the detection of ligands of angiotensin II type 1 receptor (AT(1)R). The assay makes use of stable transfected Chinese hamster ovary cells (CHO-AT(1)R) expressing the AT(1)R. A sequential saturation assay principle was used in which receptor binding sites of the CHO-AT(1)R cells are blocked by the analyte in a concentration-dependent manner. Afterwards, TAMRA-angiotensin II, a fluorescence-labeled ligand, was added to bind to the remaining free binding sites of the receptor. In consequence, the fluorescence signal determined is inversely proportional to the concentration of the analyte. Y1 - 2009 UR - http://www.springerlink.com/content/100417 U6 - https://doi.org/10.1007/s00216-009-3074-4 SN - 1618-2642 ER - TY - JOUR A1 - Zimmermann, Matthias A1 - Schünzel, Julia A1 - Safoklov, Yury A1 - Lehmann, Louise A1 - Eilebrecht, Johanna A1 - Gölz, Leah A1 - Stegemann, Tim A1 - Wagner, Marlene A1 - Klimke, Romy A1 - Steinbach, Peter T1 - MenschenRechtsMagazin : Informationen | Meinungen | Analysen N2 - Aus dem Inhalt: • Gemeinschaftliches Eigentum indigener Völker – Recht und Rechtsdurchsetzung am Fall Lhaka Honhat gegen Argentinien • „Spiel mir das Lied vom Tod“: Die Pflichten des Staates beim Umgang mit freiverantwortlicher Lebensbeendigung – Eine Untersuchung unter Berücksichtigung der deutschen und europäischen höchstrichterlichen Rechtsprechung • Die Individualbeschwerde vor dem Kinderrechtsausschuss der Vereinten Nationen: Ein Instrument zur effektiven Durchsetzung der Kinderrechte? T3 - MenschenRechtsMagazin : MRM ; Informationen, Meinungen, Analysen - 25.2020/2 Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-474009 SN - 1434-2820 VL - 25 IS - 2 SP - 77 EP - 167 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Lehmann, Anika A1 - Zheng, Weishuang A1 - Ryo, Masahiro A1 - Soutschek, Katharina A1 - Roy, Julien A1 - Rongstock, Rebecca A1 - Maaß, Stefanie A1 - Rillig, Matthias C. T1 - Fungal traits important for soil aggregation JF - Frontiers in microbiology N2 - Soil structure, the complex arrangement of soil into aggregates and pore spaces, is a key feature of soils and soil biota. Among them, filamentous saprobic fungi have well-documented effects on soil aggregation. However, it is unclear what properties, or traits, determine the overall positive effect of fungi on soil aggregation. To achieve progress, it would be helpful to systematically investigate a broad suite of fungal species for their trait expression and the relation of these traits to soil aggregation. Here, we apply a trait-based approach to a set of 15 traits measured under standardized conditions on 31 fungal strains including Ascomycota, Basidiomycota, and Mucoromycota, all isolated from the same soil. We find large differences among these fungi in their ability to aggregate soil, including neutral to positive effects, and we document large differences in trait expression among strains. We identify biomass density, i.e., the density with which a mycelium grows (positive effects), leucine aminopeptidase activity (negative effects) and phylogeny as important factors explaining differences in soil aggregate formation (SAF) among fungal strains; importantly, growth rate was not among the important traits. Our results point to a typical suite of traits characterizing fungi that are good soil aggregators, and our findings illustrate the power of employing a trait-based approach to unravel biological mechanisms underpinning soil aggregation. Such an approach could now be extended also to other soil biota groups. In an applied context of restoration and agriculture, such trait information can inform management, for example to prioritize practices that favor the expression of more desirable fungal traits. KW - soil aggregation KW - traits KW - saprobic fungi KW - random forest KW - biomass KW - density KW - leucine amino peptidases Y1 - 2020 U6 - https://doi.org/10.3389/fmicb.2019.02904 SN - 1664-302X VL - 10 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Maass, Stefanie A1 - Daphi, Daniel A1 - Lehmann, Anika A1 - Rillig, Matthias C. T1 - Transport of microplastics by two collembolan species JF - Environmental pollution N2 - Plastics, despite their great benefits, have become a ubiquitous environmental pollutant, with micro-plastic particles having come into focus most recently. Microplastic effects have been intensely studied in aquatic, especially marine systems; however, there is lack of studies focusing on effects on soil and its biota. A basic question is if and how surface-deposited microplastic particles are transported into the soil. We here wished to test if soil microarthropods, using Collembola, can transport these particles over distances of centimeters within days in a highly controlled experimental set-up. We conducted a fully factorial experiment with two collembolan species of differing body size, Folsomia candida and Proisotoma minuta, in combination with urea-formaldehyde particles of two different particle sizes. We observed significant differences between the species concerning the distance the particles were transported. F. candida was able to transport larger particles further and faster than P. minuta. Using video, we observed F candida interacting with urea-formaldehyde particles and polyethylene terephthalate fibers, showing translocation of both material types. Our data clearly show that microplastic particles can be moved and distributed by soil microarthropods. Although we did not observe feeding, it is possible that microarthropods contribute to the accumulation of microplastics in the soil food web. (C) 2017 Elsevier Ltd. All rights reserved. KW - Microplastics KW - Soil KW - Collembolans KW - Transport KW - Pollution Y1 - 2017 U6 - https://doi.org/10.1016/j.envpol.2017.03.009 SN - 0269-7491 SN - 1873-6424 VL - 225 SP - 456 EP - 459 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Kroke, Anja A1 - Schmidt, Annemarie A1 - Amini, Anna M. A1 - Kalotai, Nicole A1 - Lehmann, Andreas A1 - Haardt, Julia A1 - Bauer, Jürgen M. A1 - Bischoff-Ferrari, Heike A. A1 - Boeing, Heiner A1 - Egert, Sarah A1 - Ellinger, Sabine A1 - Kühn, Tilman A1 - Louis, Sandrine A1 - Lorkowski, Stefan A1 - Nimptsch, Katharina A1 - Remer, Thomas A1 - Schulze, Matthias B. A1 - Siener, Roswitha A1 - Stangl, Gabriele A1 - Volkert, Dorothee A1 - Zittermann, Armin A1 - Buyken, Anette E. A1 - Watzl, Bernhard A1 - Schwingshackl, Lukas T1 - Dietary protein intake and health-related outcomes: a methodological protocol for the evidence evaluation and the outline of an evidence to decision framework underlying the evidence-based guideline of the German Nutrition Society JF - European journal of nutrition N2 - Purpose: The present work aimed to delineate (i) a revised protocol according to recent methodological developments in evidence generation, to (ii) describe its interpretation, the assessment of the overall certainty of evidence and to (iii) outline an Evidence to Decision framework for deriving an evidence-based guideline on quantitative and qualitative aspects of dietary protein intake. Methods A methodological protocol to systematically investigate the association between dietary protein intake and several health outcomes and for deriving dietary protein intake recommendations for the primary prevention of various non-communicable diseases in the general adult population was developed. Results The developed methodological protocol relies on umbrella reviews including systematic reviews with or without meta-analyses. Systematic literature searches in three databases will be performed for each health-related outcome. The methodological quality of all selected systematic reviews will be evaluated using a modified version of AMSTAR 2, and the outcome-specific certainty of evidence for systematic reviews with or without meta-analysis will be assessed with NutriGrade. The general outline of the Evidence to Decision framework foresees that recommendations in the derived guideline will be given based on the overall certainty of evidence as well as on additional criteria such as sustainability. Conclusion The methodological protocol permits a systematic evaluation of published systematic reviews on dietary protein intake and its association with selected health-related outcomes. An Evidence to Decision framework will be the basis for the overall conclusions and the resulting recommendations for dietary protein intake. KW - Evidence-based guideline KW - Protein intake KW - Method KW - Prevention KW - Nutrition-related diseases Y1 - 2022 U6 - https://doi.org/10.1007/s00394-021-02789-5 SN - 1436-6207 SN - 1436-6215 VL - 61 IS - 4 SP - 2091 EP - 2101 PB - Springer Nature CY - Heidelberg ER -