TY  - JOUR
A1  - Schiffers, Katja
A1  - Schurr, Frank Martin
A1  - Tielbörger, Katja
A1  - Urbach, Carsten
A1  - Moloney, Kirk A.
A1  - Jeltsch, Florian
T1  - Dealing with virtual aggregation : a new index for analysing heterogeneous point patterns
Y1  - 2008
UR  - http://www3.interscience.wiley.com/journal/117966123/home
U6  - https://doi.org/10.1111/j.0906-7590.2008.05374.x
SN  - 0906-7590
ER  - 
TY  - JOUR
A1  - Hummel, Katja
A1  - Frank, Katja
T1  - Die Schluckfrequenz bei Gesunden in Seiten- vs. Rückenlage
Y1  - 2010
ER  - 
TY  - JOUR
A1  - Jeltsch, Florian
A1  - Blaum, Niels
A1  - Brose, Ulrich
A1  - Chipperfield, Joseph D.
A1  - Clough, Yann
A1  - Farwig, Nina
A1  - Geissler, Katja
A1  - Graham, Catherine H.
A1  - Grimm, Volker
A1  - Hickler, Thomas
A1  - Huth, Andreas
A1  - May, Felix
A1  - Meyer, Katrin M.
A1  - Pagel, Jörn
A1  - Reineking, Björn
A1  - Rillig, Matthias C.
A1  - Shea, Katriona
A1  - Schurr, Frank Martin
A1  - Schroeder, Boris
A1  - Tielbörger, Katja
A1  - Weiss, Lina
A1  - Wiegand, Kerstin
A1  - Wiegand, Thorsten
A1  - Wirth, Christian
A1  - Zurell, Damaris
T1  - How can we bring together empiricists and modellers in functional biodiversity research?
JF  - Basic and applied ecology : Journal of the Gesellschaft für Ökologie
N2  - Improving our understanding of biodiversity and ecosystem functioning and our capacity to inform ecosystem management requires an integrated framework for functional biodiversity research (FBR). However, adequate integration among empirical approaches (monitoring and experimental) and modelling has rarely been achieved in FBR. We offer an appraisal of the issues involved and chart a course towards enhanced integration. A major element of this path is the joint orientation towards the continuous refinement of a theoretical framework for FBR that links theory testing and generalization with applied research oriented towards the conservation of biodiversity and ecosystem functioning. We further emphasize existing decision-making frameworks as suitable instruments to practically merge these different aims of FBR and bring them into application. This integrated framework requires joint research planning, and should improve communication and stimulate collaboration between modellers and empiricists, thereby overcoming existing reservations and prejudices. The implementation of this integrative research agenda for FBR requires an adaptation in most national and international funding schemes in order to accommodate such joint teams and their more complex structures and data needs.
KW  - Biodiversity theory
KW  - Biodiversity experiments
KW  - Conservation management
KW  - Decision-making
KW  - Ecosystem functions and services
KW  - Forecasting
KW  - Functional traits
KW  - Global change
KW  - Monitoring programmes
KW  - Interdisciplinarity
Y1  - 2013
U6  - https://doi.org/10.1016/j.baae.2013.01.001
SN  - 1439-1791
VL  - 14
IS  - 2
SP  - 93
EP  - 101
PB  - Elsevier
CY  - Jena
ER  - 
TY  - JOUR
A1  - Warrington, Nicole
A1  - Beaumont, Robin
A1  - Horikoshi, Momoko
A1  - Day, Felix R.
A1  - Helgeland, Øyvind
A1  - Laurin, Charles
A1  - Bacelis, Jonas
A1  - Peng, Shouneng
A1  - Hao, Ke
A1  - Feenstra, Bjarke
A1  - Wood, Andrew R.
A1  - Mahajan, Anubha
A1  - Tyrrell, Jessica
A1  - Robertson, Neil R.
A1  - Rayner, N. William
A1  - Qiao, Zhen
A1  - Moen, Gunn-Helen
A1  - Vaudel, Marc
A1  - Marsit, Carmen
A1  - Chen, Jia
A1  - Nodzenski, Michael
A1  - Schnurr, Theresia M.
A1  - Zafarmand, Mohammad Hadi
A1  - Bradfield, Jonathan P.
A1  - Grarup, Niels
A1  - Kooijman, Marjolein N.
A1  - Li-Gao, Ruifang
A1  - Geller, Frank
A1  - Ahluwalia, Tarunveer Singh
A1  - Paternoster, Lavinia
A1  - Rueedi, Rico
A1  - Huikari, Ville
A1  - Hottenga, Jouke-Jan
A1  - Lyytikäinen, Leo-Pekka
A1  - Cavadino, Alana
A1  - Metrustry, Sarah
A1  - Cousminer, Diana L.
A1  - Wu, Ying
A1  - Thiering, Elisabeth Paula
A1  - Wang, Carol A.
A1  - Have, Christian Theil
A1  - Vilor-Tejedor, Natalia
A1  - Joshi, Peter K.
A1  - Painter, Jodie N.
A1  - Ntalla, Ioanna
A1  - Myhre, Ronny
A1  - Pitkänen, Niina
A1  - van Leeuwen, Elisabeth M.
A1  - Joro, Raimo
A1  - Lagou, Vasiliki
A1  - Richmond, Rebecca C.
A1  - Espinosa, Ana
A1  - Barton, Sheila J.
A1  - Inskip, Hazel M.
A1  - Holloway, John W.
A1  - Santa-Marina, Loreto
A1  - Estivill, Xavier
A1  - Ang, Wei
A1  - Marsh, Julie A.
A1  - Reichetzeder, Christoph
A1  - Marullo, Letizia
A1  - Hocher, Berthold
A1  - Lunetta, Kathryn L.
A1  - Murabito, Joanne M.
A1  - Relton, Caroline L.
A1  - Kogevinas, Manolis
A1  - Chatzi, Leda
A1  - Allard, Catherine
A1  - Bouchard, Luigi
A1  - Hivert, Marie-France
A1  - Zhang, Ge
A1  - Muglia, Louis J.
A1  - Heikkinen, Jani
A1  - Morgen, Camilla S.
A1  - van Kampen, Antoine H. C.
A1  - van Schaik, Barbera D. C.
A1  - Mentch, Frank D.
A1  - Langenberg, Claudia
A1  - Scott, Robert A.
A1  - Zhao, Jing Hua
A1  - Hemani, Gibran
A1  - Ring, Susan M.
A1  - Bennett, Amanda J.
A1  - Gaulton, Kyle J.
A1  - Fernandez-Tajes, Juan
A1  - van Zuydam, Natalie R.
A1  - Medina-Gomez, Carolina
A1  - de Haan, Hugoline G.
A1  - Rosendaal, Frits R.
A1  - Kutalik, Zoltán
A1  - Marques-Vidal, Pedro
A1  - Das, Shikta
A1  - Willemsen, Gonneke
A1  - Mbarek, Hamdi
A1  - Müller-Nurasyid, Martina
A1  - Standl, Marie
A1  - Appel, Emil V. R.
A1  - Fonvig, Cilius Esmann
A1  - Trier, Caecilie
A1  - van Beijsterveldt, Catharina E. M.
A1  - Murcia, Mario
A1  - Bustamante, Mariona
A1  - Bonàs-Guarch, Sílvia
A1  - Hougaard, David M.
A1  - Mercader, Josep M.
A1  - Linneberg, Allan
A1  - Schraut, Katharina E.
A1  - Lind, Penelope A.
A1  - Medland, Sarah Elizabeth
A1  - Shields, Beverley M.
A1  - Knight, Bridget A.
A1  - Chai, Jin-Fang
A1  - Panoutsopoulou, Kalliope
A1  - Bartels, Meike
A1  - Sánchez, Friman
A1  - Stokholm, Jakob
A1  - Torrents, David
A1  - Vinding, Rebecca K.
A1  - Willems, Sara M.
A1  - Atalay, Mustafa
A1  - Chawes, Bo L.
A1  - Kovacs, Peter
A1  - Prokopenko, Inga
A1  - Tuke, Marcus A.
A1  - Yaghootkar, Hanieh
A1  - Ruth, Katherine S.
A1  - Jones, Samuel E.
A1  - Loh, Po-Ru
A1  - Murray, Anna
A1  - Weedon, Michael N.
A1  - Tönjes, Anke
A1  - Stumvoll, Michael
A1  - Michaelsen, Kim Fleischer
A1  - Eloranta, Aino-Maija
A1  - Lakka, Timo A.
A1  - van Duijn, Cornelia M.
A1  - Kiess, Wieland
A1  - Koerner, Antje
A1  - Niinikoski, Harri
A1  - Pahkala, Katja
A1  - Raitakari, Olli T.
A1  - Jacobsson, Bo
A1  - Zeggini, Eleftheria
A1  - Dedoussis, George V.
A1  - Teo, Yik-Ying
A1  - Saw, Seang-Mei
A1  - Montgomery, Grant W.
A1  - Campbell, Harry
A1  - Wilson, James F.
A1  - Vrijkotte, Tanja G. M.
A1  - Vrijheid, Martine
A1  - de Geus, Eco J. C. N.
A1  - Hayes, M. Geoffrey
A1  - Kadarmideen, Haja N.
A1  - Holm, Jens-Christian
A1  - Beilin, Lawrence J.
A1  - Pennell, Craig E.
A1  - Heinrich, Joachim
A1  - Adair, Linda S.
A1  - Borja, Judith B.
A1  - Mohlke, Karen L.
A1  - Eriksson, Johan G.
A1  - Widen, Elisabeth E.
A1  - Hattersley, Andrew T.
A1  - Spector, Tim D.
A1  - Kaehoenen, Mika
A1  - Viikari, Jorma S.
A1  - Lehtimaeki, Terho
A1  - Boomsma, Dorret I.
A1  - Sebert, Sylvain
A1  - Vollenweider, Peter
A1  - Sorensen, Thorkild I. A.
A1  - Bisgaard, Hans
A1  - Bonnelykke, Klaus
A1  - Murray, Jeffrey C.
A1  - Melbye, Mads
A1  - Nohr, Ellen A.
A1  - Mook-Kanamori, Dennis O.
A1  - Rivadeneira, Fernando
A1  - Hofman, Albert
A1  - Felix, Janine F.
A1  - Jaddoe, Vincent W. V.
A1  - Hansen, Torben
A1  - Pisinger, Charlotta
A1  - Vaag, Allan A.
A1  - Pedersen, Oluf
A1  - Uitterlinden, Andre G.
A1  - Jarvelin, Marjo-Riitta
A1  - Power, Christine
A1  - Hypponen, Elina
A1  - Scholtens, Denise M.
A1  - Lowe, William L.
A1  - Smith, George Davey
A1  - Timpson, Nicholas J.
A1  - Morris, Andrew P.
A1  - Wareham, Nicholas J.
A1  - Hakonarson, Hakon
A1  - Grant, Struan F. A.
A1  - Frayling, Timothy M.
A1  - Lawlor, Debbie A.
A1  - Njolstad, Pal R.
A1  - Johansson, Stefan
A1  - Ong, Ken K.
A1  - McCarthy, Mark I.
A1  - Perry, John R. B.
A1  - Evans, David M.
A1  - Freathy, Rachel M.
T1  - Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
JF  - Nature genetics
N2  - Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). We used structural equation modeling to decompose the contributions of direct fetal and indirect maternal genetic effects, then applied Mendelian randomization to illuminate causal pathways. For example, both indirect maternal and direct fetal genetic effects drive the observational relationship between lower birth weight and higher later blood pressure: maternal blood pressure-raising alleles reduce offspring birth weight, but only direct fetal effects of these alleles, once inherited, increase later offspring blood pressure. Using maternal birth weight-lowering genotypes to proxy for an adverse intrauterine environment provided no evidence that it causally raises offspring blood pressure, indicating that the inverse birth weight-blood pressure association is attributable to genetic effects, and not to intrauterine programming.
Y1  - 2019
SN  - 1061-4036
SN  - 1546-1718
VL  - 51
IS  - 5
SP  - 804
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - JOUR
A1  - Middeldorp, Christel M.
A1  - Mahajan, Anubha
A1  - Horikoshi, Momoko
A1  - Robertson, Neil R.
A1  - Beaumont, Robin N.
A1  - Bradfield, Jonathan P.
A1  - Bustamante, Mariona
A1  - Cousminer, Diana L.
A1  - Day, Felix R.
A1  - De Silva, N. Maneka
A1  - Guxens, Monica
A1  - Mook-Kanamori, Dennis O.
A1  - St Pourcain, Beate
A1  - Warrington, Nicole M.
A1  - Adair, Linda S.
A1  - Ahlqvist, Emma
A1  - Ahluwalia, Tarunveer Singh
A1  - Almgren, Peter
A1  - Ang, Wei
A1  - Atalay, Mustafa
A1  - Auvinen, Juha
A1  - Bartels, Meike
A1  - Beckmann, Jacques S.
A1  - Bilbao, Jose Ramon
A1  - Bond, Tom
A1  - Borja, Judith B.
A1  - Cavadino, Alana
A1  - Charoen, Pimphen
A1  - Chen, Zhanghua
A1  - Coin, Lachlan
A1  - Cooper, Cyrus
A1  - Curtin, John A.
A1  - Custovic, Adnan
A1  - Das, Shikta
A1  - Davies, Gareth E.
A1  - Dedoussis, George V.
A1  - Duijts, Liesbeth
A1  - Eastwood, Peter R.
A1  - Eliasen, Anders U.
A1  - Elliott, Paul
A1  - Eriksson, Johan G.
A1  - Estivill, Xavier
A1  - Fadista, Joao
A1  - Fedko, Iryna O.
A1  - Frayling, Timothy M.
A1  - Gaillard, Romy
A1  - Gauderman, W. James
A1  - Geller, Frank
A1  - Gilliland, Frank
A1  - Gilsanz, Vincente
A1  - Granell, Raquel
A1  - Grarup, Niels
A1  - Groop, Leif
A1  - Hadley, Dexter
A1  - Hakonarson, Hakon
A1  - Hansen, Torben
A1  - Hartman, Catharina A.
A1  - Hattersley, Andrew T.
A1  - Hayes, M. Geoffrey
A1  - Hebebrand, Johannes
A1  - Heinrich, Joachim
A1  - Helgeland, Oyvind
A1  - Henders, Anjali K.
A1  - Henderson, John
A1  - Henriksen, Tine B.
A1  - Hirschhorn, Joel N.
A1  - Hivert, Marie-France
A1  - Hocher, Berthold
A1  - Holloway, John W.
A1  - Holt, Patrick
A1  - Hottenga, Jouke-Jan
A1  - Hypponen, Elina
A1  - Iniguez, Carmen
A1  - Johansson, Stefan
A1  - Jugessur, Astanand
A1  - Kahonen, Mika
A1  - Kalkwarf, Heidi J.
A1  - Kaprio, Jaakko
A1  - Karhunen, Ville
A1  - Kemp, John P.
A1  - Kerkhof, Marjan
A1  - Koppelman, Gerard H.
A1  - Korner, Antje
A1  - Kotecha, Sailesh
A1  - Kreiner-Moller, Eskil
A1  - Kulohoma, Benard
A1  - Kumar, Ashish
A1  - Kutalik, Zoltan
A1  - Lahti, Jari
A1  - Lappe, Joan M.
A1  - Larsson, Henrik
A1  - Lehtimaki, Terho
A1  - Lewin, Alexandra M.
A1  - Li, Jin
A1  - Lichtenstein, Paul
A1  - Lindgren, Cecilia M.
A1  - Lindi, Virpi
A1  - Linneberg, Allan
A1  - Liu, Xueping
A1  - Liu, Jun
A1  - Lowe, William L.
A1  - Lundstrom, Sebastian
A1  - Lyytikainen, Leo-Pekka
A1  - Ma, Ronald C. W.
A1  - Mace, Aurelien
A1  - Magi, Reedik
A1  - Magnus, Per
A1  - Mamun, Abdullah A.
A1  - Mannikko, Minna
A1  - Martin, Nicholas G.
A1  - Mbarek, Hamdi
A1  - McCarthy, Nina S.
A1  - Medland, Sarah E.
A1  - Melbye, Mads
A1  - Melen, Erik
A1  - Mohlke, Karen L.
A1  - Monnereau, Claire
A1  - Morgen, Camilla S.
A1  - Morris, Andrew P.
A1  - Murray, Jeffrey C.
A1  - Myhre, Ronny
A1  - Najman, Jackob M.
A1  - Nivard, Michel G.
A1  - Nohr, Ellen A.
A1  - Nolte, Ilja M.
A1  - Ntalla, Ioanna
A1  - Oberfield, Sharon E.
A1  - Oken, Emily
A1  - Oldehinkel, Albertine J.
A1  - Pahkala, Katja
A1  - Palviainen, Teemu
A1  - Panoutsopoulou, Kalliope
A1  - Pedersen, Oluf
A1  - Pennell, Craig E.
A1  - Pershagen, Goran
A1  - Pitkanen, Niina
A1  - Plomin, Robert
A1  - Power, Christine
A1  - Prasad, Rashmi B.
A1  - Prokopenko, Inga
A1  - Pulkkinen, Lea
A1  - Raikkonen, Katri
A1  - Raitakari, Olli T.
A1  - Reynolds, Rebecca M.
A1  - Richmond, Rebecca C.
A1  - Rivadeneira, Fernando
A1  - Rodriguez, Alina
A1  - Rose, Richard J.
A1  - Salem, Rany
A1  - Santa-Marina, Loreto
A1  - Saw, Seang-Mei
A1  - Schnurr, Theresia M.
A1  - Scott, James G.
A1  - Selzam, Saskia
A1  - Shepherd, John A.
A1  - Simpson, Angela
A1  - Skotte, Line
A1  - Sleiman, Patrick M. A.
A1  - Snieder, Harold
A1  - Sorensen, Thorkild I. A.
A1  - Standl, Marie
A1  - Steegers, Eric A. P.
A1  - Strachan, David P.
A1  - Straker, Leon
A1  - Strandberg, Timo
A1  - Taylor, Michelle
A1  - Teo, Yik-Ying
A1  - Thiering, Elisabeth
A1  - Torrent, Maties
A1  - Tyrrell, Jessica
A1  - Uitterlinden, Andre G.
A1  - van Beijsterveldt, Toos
A1  - van der Most, Peter J.
A1  - van Duijn, Cornelia M.
A1  - Viikari, Jorma
A1  - Vilor-Tejedor, Natalia
A1  - Vogelezang, Suzanne
A1  - Vonk, Judith M.
A1  - Vrijkotte, Tanja G. M.
A1  - Vuoksimaa, Eero
A1  - Wang, Carol A.
A1  - Watkins, William J.
A1  - Wichmann, H-Erich
A1  - Willemsen, Gonneke
A1  - Williams, Gail M.
A1  - Wilson, James F.
A1  - Wray, Naomi R.
A1  - Xu, Shujing
A1  - Xu, Cheng-Jian
A1  - Yaghootkar, Hanieh
A1  - Yi, Lu
A1  - Zafarmand, Mohammad Hadi
A1  - Zeggini, Eleftheria
A1  - Zemel, Babette S.
A1  - Hinney, Anke
A1  - Lakka, Timo A.
A1  - Whitehouse, Andrew J. O.
A1  - Sunyer, Jordi
A1  - Widen, Elisabeth E.
A1  - Feenstra, Bjarke
A1  - Sebert, Sylvain
A1  - Jacobsson, Bo
A1  - Njolstad, Pal R.
A1  - Stoltenberg, Camilla
A1  - Smith, George Davey
A1  - Lawlor, Debbie A.
A1  - Paternoster, Lavinia
A1  - Timpson, Nicholas J.
A1  - Ong, Ken K.
A1  - Bisgaard, Hans
A1  - Bonnelykke, Klaus
A1  - Jaddoe, Vincent W. V.
A1  - Tiemeier, Henning
A1  - Jarvelin, Marjo-Riitta
A1  - Evans, David M.
A1  - Perry, John R. B.
A1  - Grant, Struan F. A.
A1  - Boomsma, Dorret I.
A1  - Freathy, Rachel M.
A1  - McCarthy, Mark I.
A1  - Felix, Janine F.
T1  - The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia
BT  - design, results and future prospects
JF  - European journal of epidemiology
N2  - The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.
KW  - Genetics
KW  - Consortium
KW  - Childhood traits and disorders
KW  - Longitudinal
Y1  - 2019
U6  - https://doi.org/10.1007/s10654-019-00502-9
SN  - 0393-2990
SN  - 1573-7284
VL  - 34
IS  - 3
SP  - 279
EP  - 300
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - van der Valk, Ralf J. P.
A1  - Kreiner-Moller, Eskil
A1  - Kooijman, Marjolein N.
A1  - Guxens, Monica
A1  - Stergiakouli, Evangelia
A1  - Saaf, Annika
A1  - Bradfield, Jonathan P.
A1  - Geller, Frank
A1  - Hayes, M. Geoffrey
A1  - Cousminer, Diana L.
A1  - Koerner, Antje
A1  - Thiering, Elisabeth
A1  - Curtin, John A.
A1  - Myhre, Ronny
A1  - Huikari, Ville
A1  - Joro, Raimo
A1  - Kerkhof, Marjan
A1  - Warrington, Nicole M.
A1  - Pitkanen, Niina
A1  - Ntalla, Ioanna
A1  - Horikoshi, Momoko
A1  - Veijola, Riitta
A1  - Freathy, Rachel M.
A1  - Teo, Yik-Ying
A1  - Barton, Sheila J.
A1  - Evans, David M.
A1  - Kemp, John P.
A1  - St Pourcain, Beate
A1  - Ring, Susan M.
A1  - Smith, George Davey
A1  - Bergstrom, Anna
A1  - Kull, Inger
A1  - Hakonarson, Hakon
A1  - Mentch, Frank D.
A1  - Bisgaard, Hans
A1  - Chawes, Bo Lund Krogsgaard
A1  - Stokholm, Jakob
A1  - Waage, Johannes
A1  - Eriksen, Patrick
A1  - Sevelsted, Astrid
A1  - Melbye, Mads
A1  - van Duijn, Cornelia M.
A1  - Medina-Gomez, Carolina
A1  - Hofman, Albert
A1  - de Jongste, Johan C.
A1  - Taal, H. Rob
A1  - Uitterlinden, Andre G.
A1  - Armstrong, Loren L.
A1  - Eriksson, Johan
A1  - Palotie, Aarno
A1  - Bustamante, Mariona
A1  - Estivill, Xavier
A1  - Gonzalez, Juan R.
A1  - Llop, Sabrina
A1  - Kiess, Wieland
A1  - Mahajan, Anubha
A1  - Flexeder, Claudia
A1  - Tiesler, Carla M. T.
A1  - Murray, Clare S.
A1  - Simpson, Angela
A1  - Magnus, Per
A1  - Sengpiel, Verena
A1  - Hartikainen, Anna-Liisa
A1  - Keinanen-Kiukaanniemi, Sirkka
A1  - Lewin, Alexandra
A1  - Alves, Alexessander Da Silva Couto
A1  - Blakemore, Alexandra I. F.
A1  - Buxton, Jessica L.
A1  - Kaakinen, Marika
A1  - Rodriguez, Alina
A1  - Sebert, Sylvain
A1  - Vaarasmaki, Marja
A1  - Lakka, Timo
A1  - Lindi, Virpi
A1  - Gehring, Ulrike
A1  - Postma, Dirkje S.
A1  - Ang, Wei
A1  - Newnham, John P.
A1  - Lyytikainen, Leo-Pekka
A1  - Pahkala, Katja
A1  - Raitakari, Olli T.
A1  - Panoutsopoulou, Kalliope
A1  - Zeggini, Eleftheria
A1  - Boomsma, Dorret I.
A1  - Groen-Blokhuis, Maria
A1  - Ilonen, Jorma
A1  - Franke, Lude
A1  - Hirschhorn, Joel N.
A1  - Pers, Tune H.
A1  - Liang, Liming
A1  - Huang, Jinyan
A1  - Hocher, Berthold
A1  - Knip, Mikael
A1  - Saw, Seang-Mei
A1  - Holloway, John W.
A1  - Melen, Erik
A1  - Grant, Struan F. A.
A1  - Feenstra, Bjarke
A1  - Lowe, William L.
A1  - Widen, Elisabeth
A1  - Sergeyev, Elena
A1  - Grallert, Harald
A1  - Custovic, Adnan
A1  - Jacobsson, Bo
A1  - Jarvelin, Marjo-Riitta
A1  - Atalay, Mustafa
A1  - Koppelman, Gerard H.
A1  - Pennell, Craig E.
A1  - Niinikoski, Harri
A1  - Dedoussis, George V.
A1  - Mccarthy, Mark I.
A1  - Frayling, Timothy M.
A1  - Sunyer, Jordi
A1  - Timpson, Nicholas J.
A1  - Rivadeneira, Fernando
A1  - Bonnelykke, Klaus
A1  - Jaddoe, Vincent W. V.
T1  - A novel common variant in DCST2 is associated with length in early life and height in adulthood
JF  - Human molecular genetics
N2  - Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide association studies (Stage 1; N = 28 459). We identified seven independent top single nucleotide polymorphisms (SNPs) (P < 1 x 10(-6)) for birth length, of which three were novel and four were in or near loci known to be associated with adult height (LCORL, PTCH1, GPR126 and HMGA2). The three novel SNPs were followed-up in nine replication studies (Stage 2; N = 11 995), with rs905938 in DC-STAMP domain containing 2 (DCST2) genome-wide significantly associated with birth length in a joint analysis (Stages 1 + 2; beta = 0.046, SE = 0.008, P = 2.46 x 10(-8), explained variance = 0.05%). Rs905938 was also associated with infant length (N = 28 228; P = 5.54 x 10(-4)) and adult height (N = 127 513; P = 1.45 x 10(-5)). DCST2 is a DC-STAMP-like protein family member and DC-STAMP is an osteoclast cell-fusion regulator. Polygenic scores based on 180 SNPs previously associated with human adult stature explained 0.13% of variance in birth length. The same SNPs explained 2.95% of the variance of infant length. Of the 180 known adult height loci, 11 were genome-wide significantly associated with infant length (SF3B4, LCORL, SPAG17, C6orf173, PTCH1, GDF5, ZNFX1, HHIP, ACAN, HLA locus and HMGA2). This study highlights that common variation in DCST2 influences variation in early growth and adult height.
Y1  - 2015
U6  - https://doi.org/10.1093/hmg/ddu510
SN  - 0964-6906
SN  - 1460-2083
VL  - 24
IS  - 4
SP  - 1155
EP  - 1168
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Aichert, Ingrid
A1  - Staiger, Anja
A1  - Schulte-Mäter, Anne
A1  - Becker-Redding, Ulrike
A1  - Stahn, Corinna
A1  - Peschke, Claudia
A1  - Heide, Judith
A1  - Ott, Susan
A1  - Herrmann, Heike
A1  - Völsch, Juliane
A1  - Mayer, Jörg
A1  - Rohnke, Lucie
A1  - Frank, Ulrike
A1  - Stadie, Nicole
A1  - Jentsch, Nadine
A1  - Blech, Anke
A1  - Kurtenbach, Stephanie
A1  - Thieke, Johanna
A1  - Schröder, Astrid
A1  - Stahn, Corinna
A1  - Hörnig, Robin
A1  - Burchert, Frank
A1  - De Bleser, Ria
A1  - Heister, Julian
A1  - Bartels, Luise
A1  - Würzner, Kay-Michael
A1  - Böhme, Romy
A1  - Burmester, Juliane
A1  - Krajewski, Melanie
A1  - Nager, Wido
A1  - Jungehülsing, Gerhard Jan
A1  - Wartenburger, Isabell
A1  - Jöbges, Michael
A1  - Schwilling, Eleonore
A1  - Lidzba, Karen
A1  - Winkler, Susanne
A1  - Konietzko, Andreas
A1  - Krägeloh-Mann, Ingeborg
A1  - Rilling, Eva
A1  - Wilken, Rainer
A1  - Wismann, Kathrin
A1  - Glandorf, Birte
A1  - Hoffmann, Hannah
A1  - Hinnenkamp, Christiane
A1  - Rohlmann, Insa
A1  - Ludewigt, Jacqueline
A1  - Bittner, Christian
A1  - Orlov, Tatjana
A1  - Claus, Katrin
A1  - Ehemann, Christine
A1  - Winnecken, Andreas
A1  - Hummel, Katja
A1  - Breitenstein, Sarah
ED  - Wahl, Michael
ED  - Stahn, Corinna
ED  - Hanne, Sandra
ED  - Fritzsche, Tom
T1  - Spektrum Patholinguistik = Schwerpunktthema: Von der Programmierung zur Artikulation : Sprechapraxie bei Kindern und Erwachsenen
N2  - Das 3. Herbsttreffen Patholinguistik fand am 21. November 2009 an der Universität Potsdam statt. Der vorliegende Tagungsband enthält die drei Hauptvorträge zum Schwerpunktthema „Von der Programmierung zu Artikulation: Sprechapraxie bei Kindern und Erwachsenen“. Darüber hinaus enthält der Band die Beiträge aus dem Spektrum Patholinguistik, sowie die Abstracts der Posterpräsentationen.
N2  - The 3rd Herbsttreffen Patholinguistik was held on November 21st, 2009 at the University of Potsdam. These proceedings contain the three main lectures of the central topic „From programming to articulation: Apraxia of speech of children and adults “. Additionally this volume contains the contributions of Spektrum Patholinguistik, as well as the abstracts of the poster presentations.
T3  - Spektrum Patholinguistik - 3 
KW  - Patholinguistik
KW  - Sprechapraxie
KW  - Sprachtherapie
KW  - patholinguistics
KW  - apraxia of speech
KW  - speech and language therapy
Y1  - 2010
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-45470
SN  - 978-3-86956-079-3
SN  - 1869-3822
SN  - 1866-9433
IS  - 3
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Thulin, Mirjam
A1  - Krah, Markus
A1  - Gausemeier, Bernd
A1  - Mecklenburg, Frank
A1  - Oehme, Annegret
A1  - Tamás, Máté
A1  - Gerlach, Lisa
A1  - Gräbe, Viktoria
A1  - Wermke, Michael
A1  - Oleshkevich, Ekaterina
A1  - Arnold, Rafael D.
A1  - Wendehorst, Stephan
A1  - Talabardon, Susanne
A1  - Mays, Devi
A1  - Müller, Judith
A1  - Herskovitz, Yaakov
A1  - Garloff, Katja
A1  - Kellenbach, Katharina von
A1  - Held, Marcus
A1  - Grözinger, Karl Erich
ED  - Thulin, Mirjam
ED  - Krah, Markus
ED  - Pick, Bianca
T1  - PaRDeS : Journal of the Association for Jewish Studies in Germany = Jewish Families and Kinship in the Early Modern and Modern Eras
T2  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien
T2  - PaRDeS : Journal of the Association for Jewish Studies in Germany
N2  - The Jewish family has been the subject of much admiration and analysis, criticism and myth-making, not just but especially in modern times. As a field of inquiry, its place is at the intersection – or in the shadow – of the great topics in Jewish Studies and its contributing disciplines. Among them are the modernization and privatization of Judaism and Jewish life; integration and distinctiveness of Jews as individuals and as a group; gender roles and education. These and related questions have been the focus of modern Jewish family research, which took shape as a discipline in the 1910s.

This issue of PaRDeS traces the origins of academic Jewish family research and takes stock of its development over a century, with its ruptures that have added to the importance of familial roots and continuities. A special section retrieves the founder of the field, Arthur Czellitzer (1871–1943), his biography and work from oblivion and places him in the context of early 20th-century science and Jewish life.

The articles on current questions of Jewish family history reflect the topic’s potential for shedding new light on key questions in Jewish Studies past and present. Their thematic range – from 13th-century Yiddish Arthurian romances via family-based business practices in 19th-century Hungary and Germany, to concepts of Jewish parenthood in Imperial Russia – illustrates the broad interest in Jewish family research as a paradigm for early modern and modern Jewish Studies.
T3  - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien e.V. - 26 
KW  - Modern Jewish history
KW  - family history
KW  - early modern history
KW  - Jewish Studies
KW  - genealogy
KW  - Moderne Jüdische Geschichte
KW  - Familiengeschichte
KW  - Frühe Neuzeit
KW  - Jüdische Studien
KW  - Genealogie
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-473654
SN  - 978-3-86956-493-7
SN  - 1614-6492
SN  - 1862-7684
IS  - 26
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Hummel, Katja
A1  - Frank, Ulrike
T1  - Die Schluckfrequenz bei Gesunden in Seiten- vs. Rückenlage
JF  - Spektrum Patholinguistik
Y1  - 2010
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-47077
SN  - 1866-9085
SN  - 1866-9433
VL  - 3
SP  - 187
EP  - 190
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Moloney, Kirk A.
A1  - Holzapfel, Claus
A1  - Tielbörger, Katja
A1  - Jeltsch, Florian
A1  - Schurr, Frank Martin
T1  - Rethinking the common garden in invasion research
N2  - In common garden experiments, a number of genotypes are raised in a common environment in order to quantify the genetic component of phenotypic variation. Common gardens are thus ideally suited for disentangling how genetic and environmental factors contribute to the success of invasive species in their new non-native range. Although common garden experiments are increasingly employed in the study of invasive species, there has been little discussion about how these experiments should be designed for greatest utility. We argue that this has delayed progress in developing a general theory of invasion biology. We suggest a minimum optimal design (MOD) for common garden studies that target the ecological and evolutionary processes leading to phenotypic differentiation between native and invasive ranges. This involves four elements: (A) multiple, strategically sited garden locations, involving at the very least four gardens (2 in the native range and 2 in the invaded range); (B) careful consideration of the genetic design of the experiment; (C) standardization of experimental protocols across all gardens; and (D) care to ensure the biosafety of the experiment. Our understanding of the evolutionary ecology of biological invasions will be greatly enhanced by common garden studies, if and only if they are designed in a more systematic fashion, incorporating at the very least the MOD suggested here.
Y1  - 2009
UR  - http://www.sciencedirect.com/science/journal/14338319
U6  - https://doi.org/10.1016/j.ppees.2009.05.002
SN  - 1433-8319
ER  - 
TY  - JOUR
A1  - Kissling, W. D.
A1  - Dormann, Carsten F.
A1  - Groeneveld, Juergen
A1  - Hickler, Thomas
A1  - Kühn, Ingolf
A1  - McInerny, Greg J.
A1  - Montoya, Jose M.
A1  - Römermann, Christine
A1  - Schiffers, Katja
A1  - Schurr, Frank Martin
A1  - Singer, Alexander
A1  - Svenning, Jens-Christian
A1  - Zimmermann, Niklaus E.
A1  - O'Hara, Robert B.
T1  - Towards novel approaches to modelling biotic interactions in multispecies assemblages at large spatial extents
JF  - Journal of biogeography
N2  - Aim Biotic interactions within guilds or across trophic levels have widely been ignored in species distribution models (SDMs). This synthesis outlines the development of species interaction distribution models (SIDMs), which aim to incorporate multispecies interactions at large spatial extents using interaction matrices. Location Local to global. Methods We review recent approaches for extending classical SDMs to incorporate biotic interactions, and identify some methodological and conceptual limitations. To illustrate possible directions for conceptual advancement we explore three principal ways of modelling multispecies interactions using interaction matrices: simple qualitative linkages between species, quantitative interaction coefficients reflecting interaction strengths, and interactions mediated by interaction currencies. We explain methodological advancements for static interaction data and multispecies time series, and outline methods to reduce complexity when modelling multispecies interactions. Results Classical SDMs ignore biotic interactions and recent SDM extensions only include the unidirectional influence of one or a few species. However, novel methods using error matrices in multivariate regression models allow interactions between multiple species to be modelled explicitly with spatial co-occurrence data. If time series are available, multivariate versions of population dynamic models can be applied that account for the effects and relative importance of species interactions and environmental drivers. These methods need to be extended by incorporating the non-stationarity in interaction coefficients across space and time, and are challenged by the limited empirical knowledge on spatio-temporal variation in the existence and strength of species interactions. Model complexity may be reduced by: (1) using prior ecological knowledge to set a subset of interaction coefficients to zero, (2) modelling guilds and functional groups rather than individual species, and (3) modelling interaction currencies and species effect and response traits. Main conclusions There is great potential for developing novel approaches that incorporate multispecies interactions into the projection of species distributions and community structure at large spatial extents. Progress can be made by: (1) developing statistical models with interaction matrices for multispecies co-occurrence datasets across large-scale environmental gradients, (2) testing the potential and limitations of methods for complexity reduction, and (3) sampling and monitoring comprehensive spatio-temporal data on biotic interactions in multispecies communities.
KW  - Community ecology
KW  - ecological networks
KW  - global change
KW  - guild assembly
KW  - multidimensional complexity
KW  - niche theory
KW  - prediction
KW  - species distribution model
KW  - species interactions
KW  - trait-based community modules
Y1  - 2012
U6  - https://doi.org/10.1111/j.1365-2699.2011.02663.x
SN  - 0305-0270
VL  - 39
IS  - 12
SP  - 2163
EP  - 2178
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Thuiller, Wilfried
A1  - Muenkemueller, Tamara
A1  - Schiffers, Katja H.
A1  - Georges, Damien
A1  - Dullinger, Stefan
A1  - Eckhart, Vincent M.
A1  - Edwards, Thomas C.
A1  - Gravel, Dominique
A1  - Kunstler, Georges
A1  - Merow, Cory
A1  - Moore, Kara
A1  - Piedallu, Christian
A1  - Vissault, Steve
A1  - Zimmermann, Niklaus E.
A1  - Zurell, Damaris
A1  - Schurr, Frank Martin
T1  - Does probability of occurrence relate to population dynamics?
JF  - Ecography : pattern and diversity in ecology ; research papers forum
N2  - Interestingly, relationships between demographic parameters and occurrence probability did not vary substantially across degrees of shade tolerance and regions. Although they were influenced by the uncertainty in the estimation of the demographic parameters, we found that r was generally negatively correlated with P-occ, while N, and for most regions K, was generally positively correlated with P-occ. Thus, in temperate forest trees the regions of highest occurrence probability are those with high densities but slow intrinsic population growth rates. The uncertain relationships between demography and occurrence probability suggests caution when linking species distribution and demographic models.
Y1  - 2014
U6  - https://doi.org/10.1111/ecog.00836
SN  - 0906-7590
SN  - 1600-0587
VL  - 37
IS  - 12
SP  - 1155
EP  - 1166
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Svenning, Jens-Christian
A1  - Gravel, Dominique
A1  - Holt, Robert D.
A1  - Schurr, Frank Martin
A1  - Thuiller, Wilfried
A1  - Muenkemueller, Tamara
A1  - Schiffers, Katja H.
A1  - Dullinger, Stefan
A1  - Edwards, Thomas C.
A1  - Hickler, Thomas
A1  - Higgins, Steven I.
A1  - Nabel, Julia E. M. S.
A1  - Pagel, Jörn
A1  - Normand, Signe
T1  - The influence of interspecific interactions on species range expansion rates
JF  - Ecography : pattern and diversity in ecology ; research papers forum
Y1  - 2014
U6  - https://doi.org/10.1111/j.1600-0587.2013.00574.x
SN  - 0906-7590
SN  - 1600-0587
VL  - 37
IS  - 12
SP  - 1198
EP  - 1209
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - CHAP
A1  - Laschewsky, André
A1  - Liang, Hua
A1  - Rabe, Jürgen P.
A1  - Skrabania, Katja
A1  - Stahlhut, Frank
A1  - Weiss, Jan
A1  - Zehm, Daniel
T1  - Molecularly designed polymer colloids From giant surfactants to multicompartment micelles
T2  - Abstracts of papers : joint conference / The Chemical Institute of Cananda, CIC, American Chemical Society, ACS
Y1  - 2012
SN  - 0065-7727
VL  - 244
IS  - 32
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Fiehler, Katja
A1  - Bannert, Michael M.
A1  - Bischoff, Matthias
A1  - Blecker, Carlo
A1  - Stark, Rudolf
A1  - Vaitl, Dieter
A1  - Franz, Volker H.
A1  - Roesler, Frank
T1  - Working memory maintenance of grasp-target information in the human posterior parietal cortex
JF  - NeuroImage : a journal of brain function
N2  - Event-related functional magnetic resonance imaging was applied to identify cortical areas involved in maintaining target information in working memory used for an upcoming grasping action. Participants had to grasp with their thumb and index finger of the dominant right hand three-dimensional objects of different size and orientation. Reaching-to-grasp movements were performed without visual feedback either immediately after object presentation or after a variable delay of 2-12 s. The right inferior parietal cortex demonstrated sustained neural activity throughout the delay, which overlapped with activity observed during encoding of the grasp target. Immediate and delayed grasping activated similar motor-related brain areas and showed no differential activity. The results suggest that the right inferior parietal cortex plays an important functional role in working memory maintenance of grasp-related information. Moreover, our findings confirm the assumption that brain areas engaged in maintaining information are also involved in encoding the same information, and thus extend previous findings on working memory function of the posterior parietal cortex in saccadic behavior to reach-to-grasp movements.
Y1  - 2011
U6  - https://doi.org/10.1016/j.neuroimage.2010.09.080
SN  - 1053-8119
VL  - 54
IS  - 3
SP  - 2401
EP  - 2411
PB  - Elsevier
CY  - San Diego
ER  - 
TY  - JOUR
A1  - Seemüller, Anna
A1  - Fiehler, Katja
A1  - Rösler, Frank
T1  - Unimodal and crossmodal working memory representations of visual and kinesthetic movement trajectories
JF  - Acta psychologica : international journal of psychonomics
N2  - The present study investigated whether visual and kinesthetic stimuli are stored as multisensory or modality-specific representations in unimodal and crossmodal working memory tasks. To this end, angle-shaped movement trajectories were presented to 16 subjects in delayed matching-to-sample tasks either visually or kinesthetically during encoding and recognition. During the retention interval, a secondary visual or kinesthetic interference task was inserted either immediately or with a delay after encoding. The modality of the interference task interacted significantly with the encoding modality. After visual encoding, memory was more impaired by a visual than by a kinesthetic secondary task, while after kinesthetic encoding the pattern was reversed. The time when the secondary task had to be performed interacted with the encoding modality as well. For visual encoding, memory was more impaired, when the secondary task had to be performed at the beginning of the retention interval. In contrast, memory after kinesthetic encoding was more affected, when the secondary task was introduced later in the retention interval. The findings suggest that working memory traces are maintained in a modality-specific format characterized by distinct consolidation processes that take longer after kinesthetic than after visual encoding.
KW  - Visual representations
KW  - Kinesthetic representations
KW  - Vision
KW  - Haptics
KW  - Dual-task interference
Y1  - 2011
U6  - https://doi.org/10.1016/j.actpsy.2010.09.014
SN  - 0001-6918
VL  - 136
IS  - 1
SP  - 52
EP  - 59
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Reuschel, Johanna
A1  - Rösler, Frank
A1  - Henriques, Denise Y. P.
A1  - Fiehler, Katja
T1  - Spatial updating depends on gaze direction even after loss of vision
JF  - The journal of neuroscience
N2  - Direction of gaze (eye angle + head angle) has been shown to be important for representing space for action, implying a crucial role of vision for spatial updating. However, blind people have no access to vision yet are able to perform goal-directed actions successfully. Here, we investigated the role of visual experience for localizing and updating targets as a function of intervening gaze shifts in humans. People who differed in visual experience (late blind, congenitally blind, or sighted) were briefly presented with a proprioceptive reach target while facing it. Before they reached to the target's remembered location, they turned their head toward an eccentric direction that also induced corresponding eye movements in sighted and late blind individuals. We found that reaching errors varied systematically as a function of shift in gaze direction only in participants with early visual experience (sighted and late blind). In the late blind, this effect was solely present in people with moveable eyes but not in people with at least one glass eye. Our results suggest that the effect of gaze shifts on spatial updating develops on the basis of visual experience early in life and remains even after loss of vision as long as feedback from the eyes and head is available.
Y1  - 2012
U6  - https://doi.org/10.1523/JNEUROSCI.2714-11.2012
SN  - 0270-6474
VL  - 32
IS  - 7
SP  - 2422
EP  - 2429
PB  - Society for Neuroscience
CY  - Washington
ER  - 
TY  - JOUR
A1  - Sirocko, Frank
A1  - Dietrich, Stephan
A1  - Veres, Daniel
A1  - Grootes, Pieter M.
A1  - Schaber-Mohr, Katja
A1  - Seelos, Klemens
A1  - Nadeau, Marie-Josee
A1  - Kromer, Bernd
A1  - Rothacker, Leo
A1  - Roehner, Marieke
A1  - Krbetschek, Matthias
A1  - Appleby, Peter G.
A1  - Hambach, Ulrich
A1  - Rolf, Christian
A1  - Sudo, Masafumi
A1  - Grim, Stephanie
T1  - Multi-proxy dating of Holocene maar lakes and Pleistocene dry maar sediments in the Eifel, Germany
JF  - Quaternary science reviews : the international multidisciplinary research and review journal
N2  - During the last twelve years the ELSA Project (Eifel Laminated Sediment Archive) at Mainz University has drilled a total of about 52 cores from 27 maar lakes and filled-in maar basins in the Eifel/Germany. Dating has been completed for the Holocene cores using 6 different methods (Pb-210 and Cs-137 activities, palynostratigraphy, event markers, varve counting, C-14) In general, the different methods consistently complement one another within error margins. Event correlation was used for relating typical lithological changes with historically known events such as the two major Holocene flood events at 1342 AD and ca 800 BC. Dating of MIS2-MIS3 core sections is based on greyscale tuning, radiocarbon and OSL dating, magnetostratigraphy and tephrochronology. The lithological changes in the sediment cores demonstrate a sequence of events similar to the North Atlantic rapid climate variability of the Last Glacial Cycle. The warmest of the MIS3 interstadials was GI14, when a forest with abundant spruce covered the Eifel area from 55 to 48 ka BP, i.e. during a time when also other climate archives in Europe suggested very warm conditions. The forest of this "Early Stage 3 warm phase" developed subsequently into a steppe with scattered birch and pine, and finally into a glacial desert at around 25 ka BP. Evidence for Mono Lake and Laschamp geomagnetic excursions is found in two long cores. Several large eruptions during Middle and Late Pleistocene (Ulmener Maar - 11,000 varve years BP, Laacher See - 12,900 varve years BP, Mosenberg volcanoes/Meerfelder Maar 41-45 cal ka BP, Dumpel Maar 116 ka BP, Glees Maar - 151 ka BP) produced distinct ash-layers crucial for inter-core and inter-site correlations. The oldest investigated maar of the Eifel is Ar-40/Ar-39 dated to the time older than 520 ka BP.
KW  - Eifel maar
KW  - Laminated lake sediments
KW  - Tuning
KW  - Historical events
KW  - C-14-derived chronology
KW  - Varve counting
KW  - Luminescence dating
KW  - Palynostratigraphy
KW  - (CS)-C-137 and Pb-210 dating
KW  - Palaeomagnetism
KW  - Tephrostratigraphy
KW  - Argon-Argon dating
KW  - GIS
Y1  - 2013
U6  - https://doi.org/10.1016/j.quascirev.2012.09.011
SN  - 0277-3791
VL  - 62
SP  - 56
EP  - 76
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Iven, Claudia
A1  - Hansen, Bernd
A1  - Anders, Kristina
A1  - Starke, Andreas
A1  - Richardt, Kirsten
A1  - Prüß, Holger
A1  - El Meskioui, Martina
A1  - Haase, Tobias
A1  - Mahlberg, Lea
A1  - Wiehe, Lea
A1  - de Beer, Carola
A1  - Niepelt Karampamapa, Rebekka
A1  - Hofmann, Andrea
A1  - Stadie, Nicole
A1  - Hanne, Sandra
A1  - Thomson, Jenny
A1  - Schäfer, Blanca
A1  - Huttenlauch, Clara
A1  - Wartenburger, Isabell
A1  - Weiland, Katharina
A1  - Wirsam, Anke
A1  - Hartung, Julia
A1  - Wahl, Michael
A1  - Unger, Julia
A1  - Buschmann, Anke
A1  - Seefeld, Martin
A1  - Bethge, Anita
A1  - Fieder, Nora
A1  - Rahman, Rasha Abdel
A1  - Nousair, Iman
A1  - Klassert, Annegret
A1  - Wellmann, Caroline
A1  - Verbree, Rahel
A1  - van Rij, Jacolien
A1  - Sprenger, Simone
A1  - Mähl, Anna Luisa
A1  - Schneider, Kathleen
A1  - Kutz, Anne
A1  - Kaps, Hella
A1  - Frank, Ulrike
A1  - Brekeller, Sophie
A1  - Ryll, Katja
ED  - Breitenstein, Sarah
ED  - Burmester, Juliane
ED  - Yetim, Özlem
ED  - Fritzsche, Tom
T1  - Spektrum Patholinguistik Band 12. Schwerpunktthema: Weg(e) mit dem Stottern: Therapie und Selbsthilfe für Kinder und Erwachsene
T2  - Spektrum Patholinguistik
N2  - Das 12. Herbsttreffen Patholinguistik mit dem Schwerpunktthema »Weg(e) mit dem Stottern: Therapie und Selbsthilfe für Kinder und Erwachsene« fand am 24.11.2018 in Potsdam statt. Das Herbsttreffen wird seit 2007 jährlich vom Verband für Patholinguistik e.V. (vpl) durchgeführt. Der vorliegende Tagungsband beinhaltet die Vorträge zum Schwerpunktthema sowie Beiträge der Posterpräsentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis.
N2  - The Twelfth Autumn Meeting Patholinguistics (Herbsttreffen Patholinguistik) with its main topic »Away/A way with stuttering: Therapy and self-help for children and adults« took place in Potsdam on November 24 2018. This annual meeting has been organised since 2007 by the Association for Patholinguistics (Verband für Patholinguistik e.V./vpl). The present proceedings contain all talks on the main topic as well as contributions from the poster session covering a broad range of areas in speech/language therapy research and practice.
T3  - Spektrum Patholinguistik - 12 
KW  - Patholinguistik
KW  - Sprachtherapie
KW  - Stottern
KW  - Redeflussstörungen
KW  - Selbsthilfe
KW  - patholinguistics
KW  - speech/language therapy
KW  - stuttering
KW  - fluency disorder
KW  - self-help
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-437002
SN  - 978-3-86956-479-1
SN  - 1866-9085
SN  - 1866-9433
IS  - 12
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Laucht, Manfred
A1  - Becker, Katja
A1  - Frank, Josef
A1  - Schmidt, Martin H.
A1  - Esser, Günter
A1  - Treutlein, Jens
A1  - Skowronek, Markus H.
A1  - Schumann, Gunter
T1  - Genetic variation in dopamine pathways differentially associated with smoking progression in adolescence
N2  - Objective: To clarify the nature of the association between dopamine genes and smoking by examining whether genetic variability in components of the dopamine pathway could explain refined phenotypes in adolescent smoking progression. Method: Data are from an ongoing prospective study of the long-term outcome of early risk factors studied since birth. At age 15 years, 220 participants (108 males, 112 females) completed a self-report questionnaire measuring smoking behavior and were genotyped for five dopamine gene variants. Results: Smoking initiation was related to allelic variation in the dopamine D-4 receptor gene (DRD4), whereas smoking continuation and dependence showed association with the dopamine D-2 receptor gene (DRD2). Adolescents with the seven-repeat allele of the common DRD4 exon 3 polymorphism had rates of ever smoking that were significantly higher than in those with other genotypes. Once smoking started, carriers of the T allele of a single nucleotide polymorphism of DRD2 (rs4648317) reported higher rates of current smoking and scored higher on nicotine dependence than their allelic counterparts. Among current smokers, intention to quit was significantly lower in adolescents homozygous for the 10-repeat allele of the common dopamine transporter 3 untranslated region polymorphism. Conclusions: Our results provide preliminary evidence of genetic influences on different stages of smoking and suggest the importance of specific dopamine genes in smoking progression in adolescence.
Y1  - 2008
U6  - https://doi.org/10.1097/Chi.0b013e31816bff77
SN  - 0890-8567
ER  - 
TY  - JOUR
A1  - Burkart, Michael
A1  - Alsleben, Katja
A1  - Lachmuth, Susanne
A1  - Schumacher, Juliane
A1  - Hofmann, Ralf
A1  - Jeltsch, Florian
A1  - Schurr, Frank Martin
T1  - Recruitment requirements of the rare and threatened Juncus atratus
N2  - The long-term persistence of populations and species depends on the successful recruitment of individuals. The generative recruitment of plants may be limited by a lack of suitable germination and establishment conditions. Establishment limitation may especially be caused by the competitive effect of surrounding dense vegetation, which is believed to restrict the recruitment success of many plant species to small open patches ('safe sites'). We conducted experiments to clarify the roles of germination and seedling establishment as limiting processes in the recruitment of Juncus atratus Krock., a rare and threatened herbaceous perennial river corridor plant in Central Europe. Light intensity had a positive effect on germination. However, some seedlings emerged even in total darkness and the germination rate at 1% light intensity was more than half of that at 60% light intensity. Seedling establishment in the field after 10 weeks was 30% on bare ground, but it was close to zero in grassland. Establishment in the growth chamber after 8 weeks was close to 75% for seedlings that germinated underwater, but only about 35% for seedlings that germinated afloat. Furthermore, establishment decreased with flooding duration on bare ground, but increased with flooding duration in grassland. These data indicate that establishment, rather than germination, is a critical life stage in Central European populations off. atratus. They furthermore indicate that the competition of surrounding vegetation for water limits seedling establishment under field conditions without flooding, largely restricting establishment success to bare ground habitats. In contrast, grassland is more suitable for the recruitment off. atratus than bare ground under prolonged flooding. Grassland may facilitate the establishment off. atratus seedlings during long- lasting floods by supplying oxygen to the soil through aerenchyma. The shift from competition to facilitation in grassland occurred after 30 days of flooding, i.e. within the ontogeny of individual plants. The specific recruitment requirements off. arrows may be a main cause of its rarity in modern Central Europe. In order to prevent regional extinction off. atratus, we suggest maintaining or re-establishing natural hydrodynamics in the species' habitats.
Y1  - 2010
UR  - http://www.sciencedirect.com/science/journal/03672530
U6  - https://doi.org/10.1016/j.flora.2009.08.003
SN  - 0367-2530
ER  - 
TY  - CHAP
A1  - Cassel, Michael
A1  - Carlsohn, Anja
A1  - Froehlich, Katja
A1  - Mayer, Frank
T1  - Achilles tendinopathy in adolescent athletes using ultrasound and clinical examination
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2013
SN  - 0195-9131
SN  - 1530-0315
VL  - 45
IS  - 5
SP  - 350
EP  - 350
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - CHAP
A1  - Wochatz, Monique
A1  - Cassel, Michael
A1  - König, Niklas
A1  - Fröhlich, Katja
A1  - Mayer, Frank
T1  - Intra- and inter-observer variability of a retrospective analysis of achilles tendon ultrasound scans
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2013
SN  - 0195-9131
SN  - 1530-0315
VL  - 45
IS  - 5
SP  - 239
EP  - 239
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Cassel, Michael
A1  - Carlsohn, Anja
A1  - Fröhlich, Katja
A1  - John, Mareike
A1  - Riegels, N.
A1  - Mayer, Frank
T1  - Tendon Adaptation to Sport-specific Loading in Adolescent Athletes
JF  - International journal of sports medicine
N2  - Tendon adaptation due to mechanical loading is controversially discussed. However, data concerning the development of tendon thickness in adolescent athletes is sparse. The purpose of this study was to examine possible differences in Achilles (AT) and patellar tendon (PT) thickness in adolescent athletes while considering age, gender and sport-specific loading. In 500 adolescent competitive athletes of 16 different sports and 40 recreational controls both ATs and PTs were sonographically measured. Subjects were divided into 2 age groups (< 13; &#8805; 13 years) and 6 sport type categories (ball, combat, and water sports, combined disciplines, cycling, controls). In addition, 3 risk groups (low, moderate, high) were created according to the athlete’s risk of developing tendinopathy. AT and PT thickness did not significantly differ between age groups (AT/PT:<13: 5.4±0.7 mm/3.6±0.5 mm;&#8805;13: 5.3±0.7 mm/3.6±0.5 mm). In both age groups males presented higher tendon thickness than females (p<0.001). AT thickness was highest in ball sports/cyclists and lowest in controls (p&#8804;0.002). PT thickness was greatest in water sports and lowest in controls (p=0.02). High risk athletes presented slightly higher AT thickness compared to the low risk group (p=0.03). Increased AT and PT thickness in certain sport types compared to controls supports the hypothesis of structural tendon adaptation due to sport-specific loading.
KW  - achilles and patellar tendon
KW  - training adaptation
KW  - tendon thickness
KW  - standard values
KW  - sonography
Y1  - 2016
U6  - https://doi.org/10.1055/s-0035-1559772
SN  - 0172-4622
SN  - 1439-3964
VL  - 37
SP  - 159
EP  - 164
PB  - Thieme
CY  - Stuttgart
ER  - 
TY  - CHAP
A1  - Intziegianni, Konstantina
A1  - Cassel, Michael
A1  - Hain, Gerrit
A1  - Fröhlic, Katja
A1  - Mayer, Frank
T1  - Reliability of sonographic assessment of Achilles tendon cross-sectional area at rest and maximal voluntary contraction
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2014
SN  - 0195-9131
SN  - 1530-0315
VL  - 46
IS  - 5
SP  - 47
EP  - 47
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Cassel, Michael
A1  - Baur, Heiner
A1  - Hirschmueller, Anja
A1  - Carlsohn, Anja
A1  - Fröhlich, Katja
A1  - Mayer, Frank
T1  - Prevalence of Achilles and patellar tendinopathy and their association to intratendinous changes in adolescent athletes
JF  - Scandinavian journal of medicine & science in sports
N2  - Achilles (AT) and patellar tendons (PT) are commonly affected by tendinopathy in adult athletes but prevalence of symptoms and morphological changes in adolescents is unclear. The study aimed to determine prevalence of tendinopathy and intratendinous changes in ATs and PTs of adolescent athletes. A total of 760 adolescent athletes (13.0 +/- 1.9 years; 160 +/- 13cm; 50 +/- 14kg) were examined. History, local clinical examination, and longitudinal Doppler ultrasound analysis for both ATs and PTs were performed including identification of intratendinous echoic changes and vascularization. Diagnosis of tendinopathy was complied clinically in case of positive history of tendon pain and tendon pain on palpation. Achilles tendinopathy was diagnosed in 1.8% and patellar tendinopathy in 5.8%. Vascularizations were visible in 3.0% of ATs and 11.4% of PTs, hypoechogenicities in 0.7% and 3.2% as well as hyperechogenicities in 0% and 0.3%, respectively. Vascularizations and hypoechogenicities were statistically significantly more often in males than in females (P0.02). Subjects with patellar tendinopathy had higher prevalence of structural intratendinous changes than those without PT symptoms (P0.001). In adolescent athletes, patellar tendinopathy is three times more frequent compared with Achilles tendinopathy. Longitudinal studies are necessary to investigate physiological or pathological origin of vascularizations and its predictive value in development of tendinopathy.
KW  - Prevalence
KW  - tendinopathy
KW  - sonography
KW  - Doppler ultrasound
KW  - vascularization
KW  - hypoechogenicities
KW  - hyperechogenicities
KW  - adolescent athletes
Y1  - 2015
U6  - https://doi.org/10.1111/sms.12318
SN  - 0905-7188
SN  - 1600-0838
VL  - 25
IS  - 3
SP  - e310
EP  - e318
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Intziegianni, Konstantina
A1  - Cassel, Michael
A1  - König, Niklas
A1  - Müller, Steffen
A1  - Fröhlich, Katja
A1  - Mayer, Frank
T1  - Ultrasonography for the assessment of the structural properties of the Achilles tendon in asymptomatic individuals: An intra-rater reproducibility study
JF  - Isokinetics and exercise science : official journal of the European Isokinetic Society
N2  - BACKGROUND: Reproducible measurements of tendon structural properties are a prerequisite for accurate diagnosis of tendon disorders and for determination of their mechanical properties. Despite the widely used application of Ultrasonography (US) in musculoskeletal assessment, its operator dependency and lack of standardization influences the consistency of the measurement.
 OBJECTIVE: To evaluate the intra-rater reproducibility of a standardized US method assessing the structural properties of the Achilles tendon (AT).
 METHODS: Sixteen asymptomatic participants were positioned prone on an isokinetic dynamometer with the knee extended and ankle at 90. flexion. US was used to assess AT-length, cross-sectional area (CSA), and AT-elongation during isometric plantarflexion contraction. The intra-rater reproducibility was assessed by ICC (2.1), Test-Retest Variability (TRV, %), Bland-Altman analyses (Bias +/- LoA [1.96*SD]), and Standard-Error of Measurement (SEM).
 RESULTS: Measurements of AT-length demonstrated an ICC of 0.93, TRV of 4.5 +/- 3.9%, Bias +/- LoA of -2.8 +/- 25.0 mm and SEM of 6.6 mm. AT-CSA showed an ICC of 0.79, TRV of 8.7 +/- 9.6%, Bias +/- LoA of 1.7 +/- 19.4 mm(2) and SEM of 5.3 mm(2). AT-elongation revealed an ICC of 0.92, TRV of 12.9 +/- 8.9%, Bias +/- LoA of 0.3 +/- 5.7 mm and SEM of 1.5 mm.
 CONCLUSIONS: The presented methodology allows a reproducible assessment of Achilles tendon structural properties when performed by a single rater.
KW  - Ultrasonography
KW  - Achilles tendon
KW  - reproducibility
KW  - isokinetic
Y1  - 2015
U6  - https://doi.org/10.3233/IES-150586
SN  - 0959-3020
SN  - 1878-5913
VL  - 23
IS  - 4
SP  - 263
EP  - 270
PB  - IOS Press
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Kopinski, Stephan
A1  - Engel, Tilman
A1  - Cassel, Michael
A1  - Fröhlich, Katja
A1  - Mayer, Frank
A1  - Carlsohn, Anja
T1  - Ultrasound Applied to Subcutaneous Fat Tissue Measurements in International Elite Canoeists
JF  - International journal of sports medicine
N2  - Subcutaneous adipose tissue (SAT) measurements with ultrasound have recently been introduced to assess body fat in elite athletes. However, appropriate protocols and data on various groups of athletes are missing. We investigated intra-rater reliability of SAT measurements using ultrasound in elite canoe athletes. 25 international level canoeists (18 male, 7 female; 23 +/- 4 years; 81 +/- 11 kg; 1.83 +/- 0.09 m; 20 +/- 3 training h/wk) were measured on 2 consecutive days. SAT was assessed with B-mode ultrasound at 8 sites (ISAK): triceps, subscapular, biceps, iliac crest, supraspinal, abdominal, front thigh, medial calf, and quantified using image analysis software. Data was analyzed descriptively (mean +/- SD, [range]). Coefficient of variation (CV %), intraclass correlation coefficient (ICC, 2.1) and absolute (LoA) and ratio limits of agreement (RLoA) were calculated for day-to-day reliability. Mean sum of SAT thickness was 30.0 +/- 19.4 mm [8.0, 80.1 mm], with 3.9 +/- 1.8 mm [1.2 mm subscapular, 8.0 mm abdominal] for individual sites. CV for the sum of sites was 4.7 %, ICC 0.99, LoA 1.7 +/- 3.6 mm, RLoA 0.940 (*/divided by 1.155). Measuring SAT with ultrasound has proved to have excellent day-to-day reliability in elite canoe athletes. Recommendations for standardization of the method will further increase accuracy and reproducibility.
KW  - subcutaneous adipose tissue
KW  - skinfold thickness
KW  - elite athletes
KW  - body composition
KW  - ultrasonography
Y1  - 2015
U6  - https://doi.org/10.1055/s-0035-1555857
SN  - 0172-4622
SN  - 1439-3964
VL  - 36
IS  - 14
SP  - 1134
EP  - 1141
PB  - Thieme
CY  - Stuttgart
ER  -