TY  - JOUR
A1  - Archambault, S.
A1  - Archer, A.
A1  - Benbow, W.
A1  - Buchovecky, M.
A1  - Bugaev, V.
A1  - Cerruti, M.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Falcone, A.
A1  - Alonso, M. Fernandez
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Griffin, S.
A1  - Hutten, M.
A1  - Hervet, O.
A1  - Holder, J.
A1  - Humensky, T. B.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kieda, D.
A1  - Krause, M.
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - Maier, G.
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Pohl, M.
A1  - Popkow, A.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rovero, A. C.
A1  - Sadeh, I.
A1  - Shahinyan, K.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Weisgarber, T.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Zitzer, B.
T1  - Search for Magnetically Broadened Cascade Emission from Blazars with VERITAS
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We present a search for magnetically broadened gamma-ray emission around active galactic nuclei (AGNs), using VERITAS observations of seven hard-spectrum blazars. A cascade process occurs when multi-TeV gamma-rays from an AGN interact with extragalactic background light (EBL) photons to produce electron-positron pairs, which then interact with cosmic microwave background photons via inverse-Compton scattering to produce gamma-rays. Due to the deflection of the electron- positron pairs, a non-zero intergalactic magnetic field (IGMF) would potentially produce detectable effects on the angular distribution of the cascade emission. In particular, an angular broadening compared to the unscattered emission could occur. Through non-detection of angularly broadened emission from 1ES 1218 vertical bar 304, the source with the largest predicted cascade fraction, we exclude a range of IGMF strengths around 10(-14) G at the 95% confidence level. The extent of the exclusion range varies with the assumptions made about the intrinsic spectrum of 1ES. 1218+304 and the EBL model used in the simulation of the cascade process. All of the sources are used to set limits on the flux due to extended emission.
KW  - BL Lacertae objects: general
KW  - galaxies: active
KW  - gamma rays: galaxies
KW  - magnetic fields
Y1  - 2017
U6  - https://doi.org/10.3847/1538-4357/835/2/288
SN  - 0004-637X
SN  - 1538-4357
VL  - 835
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Archer, A.
A1  - Benbow, W.
A1  - Bird, R.
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Bugaev, V.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Daniel, M. K.
A1  - Falcone, A.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fleischhack, H.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Hanna, D.
A1  - Hervet, O.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Hutten, M.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kelley-Hoskins, N.
A1  - Kieda, D.
A1  - Krause, M.
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Maier, G.
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nieto, D.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Park, N.
A1  - Petrashyk, A.
A1  - Pohl, Martin
A1  - Popkow, A.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rulten, C.
A1  - Sadeh, I.
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weiner, O. M.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Wissel, S. A.
A1  - Zitzer, B.
T1  - Measurement of the iron spectrum in cosmic rays by VERITAS
JF  - Physical review : D, Particles, fields, gravitation, and cosmology
N2  - We present a new measurement of the energy spectrum of iron nuclei in cosmic rays from 20 TeV to 500 TeV; The measurement makes use of a template-based analysis method, which, for the first time, is applied to the energy reconstruction of iron-induced air showers recorded by the VERITAS array of imaging atmospheric Cherenkov telescopes. The event selection makes use of the direct Cherenkov light which is emitted by charged particles before the first interaction, as well as other parameters related to the shape of the recorded air shower images. The measured spectrum is well described by a power law dF/dE = f(0) center dot (E/E-0)(-gamma) over the full energy range, with gamma = 2.82 +/- 0.30(stat)(-0.27)(+0.24)(syst) and f(0) = (4.82 +/- 0.98(stat)(-2.70)(+2.12)(syst)) x 10(-7) m(-2) s(-1) TeV-1 sr(-1) at E-0 = 50 TeV, with no indication of a cutoff or spectral break. The measured differential flux is compatible with previous results, with improved statistical uncertainty at the highest energies.
Y1  - 2018
U6  - https://doi.org/10.1103/PhysRevD.98.022009
SN  - 2470-0010
SN  - 2470-0029
VL  - 98
IS  - 2
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - JOUR
A1  - Archer, A.
A1  - Benbow, Wystan
A1  - Bird, Ralph
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Bugaev, V
A1  - Cui, Wei
A1  - Danie, M. K.
A1  - Falcone, A.
A1  - Feng, Qi
A1  - Finley, John P.
A1  - Flinders, A.
A1  - Fortson, L.
A1  - Furniss, Amy
A1  - Gillanders, Gerard H.
A1  - Huttens, M.
A1  - Hanna, David
A1  - Hervet, O.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Johnson, Caitlin A.
A1  - Kaaret, Philip
A1  - Kar, P.
A1  - Kelley-Hoskins, N.
A1  - Kieda, David
A1  - Krause, Maria
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Mukherjee, Reshmi
A1  - Nieto, Daniel
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Park, Nahee
A1  - Petrashyk, A.
A1  - Pohl, Martin
A1  - Popkow, Alexis
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynold, P. T.
A1  - Richards, Gregory T.
A1  - Roache, E.
A1  - Rulten, C.
A1  - Sadeh, I
A1  - Sembroski, G. H.
A1  - Shahinyan, Karlen
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weiner, O. M.
A1  - Weinstein, A.
A1  - Wells, R. M.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, David A.
A1  - Brisken, W. F.
A1  - Pontrelli, P.
T1  - HESS J1943+213
BT  - An extreme blazar shining through the galactic plane
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - HESS J1943+213 is a very high energy (VHE; > 100 GeV) gamma-ray source in the direction of the Galactic plane. Studies exploring the classification of the source are converging toward its identification as an extreme synchrotron BL Lac object. Here we present 38 hr of VERITAS observations of HESS J1943+213 taken over 2 yr. The source is detected with a significance of similar to 20 standard deviations, showing a remarkably stable flux and spectrum in VHE gamma-rays. Multifrequency Very Long Baseline Array (VLBA) observations of the source confirm the extended, jet-like structure previously found in the 1.6 GHz band with the European VLBI Network and detect this component in the 4.6 and 7.3 GHz bands. The radio spectral indices of the core and the jet and the level of polarization derived from the VLBA observations are in a range typical for blazars. Data from VERITAS, Fermi-LAT, Swift-XRT, the FLWO 48 ' telescope, and archival infrared and hard X-ray observations are used to construct and model the spectral energy distribution (SED) of the source with a synchrotron self-Compton model. The well-measured gamma-ray peak of the SED with VERITAS and Fermi-LAT provides constraining upper limits on the source redshift. Possible contribution of secondary gamma-rays from ultra-high-energy cosmic-ray-initiated electromagnetic cascades to the gamma-ray emission is explored, finding that only a segment of the VHE spectrum can be accommodated with this process. A variability search is performed across X-ray and gamma-ray bands. No statistically significant flux or spectral variability is detected.
KW  - astroparticle physics
KW  - BL Lacertae objects: individual (HESS J1943+213, VER J1943+213)
KW  - galaxies: active
KW  - galaxies: jets
KW  - galaxies: nuclei
KW  - gamma rays: galaxies
Y1  - 2018
U6  - https://doi.org/10.3847/1538-4357/aacbd0
SN  - 0004-637X
SN  - 1538-4357
VL  - 862
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Abeysekara, A. U.
A1  - Archer, A.
A1  - Aune, Taylor
A1  - Benbow, Wystan
A1  - Bird, Ralph
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Bugaev, V.
A1  - Cui, Wei
A1  - Daniel, M. K.
A1  - Falcone, A.
A1  - Feng, Qi
A1  - Finley, John P.
A1  - Fleischhack, H.
A1  - Flinders, A.
A1  - Fortson, L.
A1  - Furniss, Amy
A1  - Gotthelf, Eric V.
A1  - Grube, J.
A1  - Hanna, David
A1  - Hervet, O.
A1  - Holder, J.
A1  - Huang, K.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Huetten, M.
A1  - Johnson, Caitlin A.
A1  - Kaaret, Philip
A1  - Kar, P.
A1  - Kelley-Hoskins, N.
A1  - Kertzman, M.
A1  - Kieda, David
A1  - Krause, Maria
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - Maier, Gernot
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Mukherjee, Reshmi
A1  - Ong, R. A.
A1  - Otte, Adam Nepomuk
A1  - Pandel, Dirk
A1  - Park, Nahee
A1  - Petrashyk, A.
A1  - Pohl, Martin
A1  - Popkow, Alexis
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, Gregory T.
A1  - Roache, E.
A1  - Rousselle, J.
A1  - Rulten, C.
A1  - Sadeh, I.
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Shahinyan, Karlen
A1  - Tyler, J.
A1  - Vassiliev, V. V.
A1  - Wakely, S. P.
A1  - Ward, J. E.
A1  - Weinstein, A.
A1  - Wells, R. M.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, David A.
A1  - Zitzer, B.
T1  - A Very High Energy gamma-Ray Survey toward the Cygnus Region of the Galaxy
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We present results from deep observations toward the Cygnus region using 300 hr of very high energy (VHE)gamma-ray data taken with the VERITAS Cerenkov telescope array and over 7 yr of high-energy.-ray data taken with the Fermi satellite at an energy above 1 GeV. As the brightest region of diffuse gamma-ray emission in the northern sky, the Cygnus region provides a promising area to probe the origins of cosmic rays. We report the identification of a potential Fermi-LAT counterpart to VER J2031+415 (TeV J2032+4130) and resolve the extended VHE source VER J2019+368 into two source candidates (VER J2018+367* and VER J2020+368*) and characterize their energy spectra. The Fermi-LAT morphology of 3FGL J2021.0+4031e (the Gamma Cygni supernova remnant) was examined, and a region of enhanced emission coincident with VER J2019+407 was identified and jointly fit with the VERITAS data. By modeling 3FGL J2015.6+3709 as two sources, one located at the location of the pulsar wind nebula CTB 87 and one at the quasar QSO J2015+371, a continuous spectrum from 1 GeV to 10 TeV was extracted for VER J2016+371 (CTB 87). An additional 71 locations coincident with Fermi-LAT sources and other potential objects of interest were tested for VHE gamma-ray emission, with no emission detected and upper limits on the differential flux placed at an average of 2.3% of the Crab Nebula flux. We interpret these observations in a multiwavelength context and present the most detailed gamma-ray view of the region to date.
KW  - acceleration of particles
KW  - cosmic rays
KW  - gamma rays: general
KW  - ISM: supernova remnants
Y1  - 2018
U6  - https://doi.org/10.3847/1538-4357/aac4a2
SN  - 0004-637X
SN  - 1538-4357
VL  - 861
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Abeysekara, A. U.
A1  - Archer, A.
A1  - Benbow, Wystan
A1  - Bird, Ralph
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Bugaev, V.
A1  - Connolly, M. P.
A1  - Cui, Wei
A1  - Errando, Manel
A1  - Falcone, A.
A1  - Feng, Qi
A1  - Finley, John P.
A1  - Flinders, A.
A1  - Fortson, L.
A1  - Furniss, Amy
A1  - Gillanders, Gerard H.
A1  - Huetten, M.
A1  - Hanna, David
A1  - Hervet, O.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Johnson, Caitlin A.
A1  - Kaaret, Philip
A1  - Kar, P.
A1  - Kelley-Hoskins, N.
A1  - Kertzman, M.
A1  - Kieda, David
A1  - Krause, Maria
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - Maier, Gernot
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Mukherjee, Reshmi
A1  - Ong, R. A.
A1  - Park, N.
A1  - Perkins, Jeremy S.
A1  - Petrashyk, A.
A1  - Pohl, Martin
A1  - Popkow, Alexis
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, Gregory T.
A1  - Roache, E.
A1  - Rulten, C.
A1  - Sadeh, I.
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Shahinyan, Karlen
A1  - Tyler, J.
A1  - Wakely, S. P.
A1  - Weiner, O. M.
A1  - Weinstein, A.
A1  - Wells, R. M.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, David A.
A1  - Zitzer, B.
A1  - Vurm, Indrek
A1  - Beloborodov, Andrei
T1  - A Strong Limit on the Very-high-energy Emission from GRB 150323A
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - On 2015 March 23, the Very Energetic Radiation Imaging Telescope Array System (VERITAS) responded to a Swift-Burst Alert Telescope (BAT) detection of a gamma-ray burst, with observations beginning 270 s after the onset of BAT emission, and only 135 s after the main BAT emission peak. No statistically significant signal is detected above 140 GeV. The VERITAS upper limit on the fluence in a 40-minute integration corresponds to about 1% of the prompt fluence. Our limit is particularly significant because the very-high-energy (VHE) observation started only similar to 2 minutes after the prompt emission peaked, and Fermi-Large Area Telescope observations of numerous other bursts have revealed that the high-energy emission is typically delayed relative to the prompt radiation and lasts significantly longer. Also, the proximity of GRB 150323A (z = 0.593) limits the attenuation by the extragalactic background light to similar to 50% at 100-200 GeV. We conclude that GRB 150323A had an intrinsically very weak high-energy afterglow, or that the GeV spectrum had a turnover below similar to 100 GeV. If the GRB exploded into the stellar wind of a massive progenitor, the VHE non-detection constrains the wind density parameter to be A greater than or similar to 3 x 10(11) g . cm(-1), consistent with a standard Wolf-Rayet progenitor. Alternatively, the VHE emission from the blast wave would be weak in a very tenuous medium such as the interstellar medium, which therefore cannot be ruled out as the environment of GRB 150323A.
KW  - gamma rays: general
KW  - gamma-ray burst: general
KW  - gamma-ray burst: individual (GRB 150323A)
Y1  - 2018
U6  - https://doi.org/10.3847/1538-4357/aab371
SN  - 0004-637X
SN  - 1538-4357
VL  - 857
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Archer, A.
A1  - Benbow, W.
A1  - Bird, R.
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Daniel, M. K.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Gillanders, G.
A1  - Huetten, M.
A1  - Hanna, D.
A1  - Hervet, O.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Johnson, C. A.
A1  - Kaaret, P.
A1  - Kar, P.
A1  - Kelley-Hoskins, N.
A1  - Kertzman, M.
A1  - Kieda, D.
A1  - Krause, M.
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - Maier, G.
A1  - McArthur, S.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Ong, R. A.
A1  - Otte, A. N.
A1  - Petrashyk, A.
A1  - Pohl, M.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rulten, C.
A1  - Sadeh, I.
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Staszak, D.
A1  - Sushch, I.
A1  - Wakely, S. P.
A1  - Wells, R. M.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, D. A.
A1  - Williamson, T. J.
A1  - Zitzer, B.
T1  - Measurement of cosmic-ray electrons at TeV energies by VERITAS
JF  - Physical review : D, Particles, fields, gravitation, and cosmology
N2  - Cosmic-ray electrons and positrons (CREs) at GeV-TeV energies are a unique probe of our local Galactic neighborhood. CREs lose energy rapidly via synchrotron radiation and inverse-Compton scattering processes while propagating within the Galaxy, and these losses limit their propagation distance. For electrons with TeV energies, the limit is on the order of a kiloparsec. Within that distance, there are only a few known astrophysical objects capable of accelerating electrons to such high energies. It is also possible that the CREs are the products of the annihilation or decay of heavy dark matter (DM) particles. VERITAS, an array of imaging air Cherenkov telescopes in southern Arizona, is primarily utilized for gamma-ray astronomy but also simultaneously collects CREs during all observations. We describe our methods of identifying CREs in VERITAS data and present an energy spectrum, extending from 300 GeV to 5 TeV, obtained from approximately 300 hours of observations. A single power-law fit is ruled out in VERITAS data. We find that the spectrum of CREs is consistent with a broken power law, with a break energy at 710 +/- 40(stat) +/- 140(syst) GeV.
Y1  - 2018
U6  - https://doi.org/10.1103/PhysRevD.98.062004
SN  - 2470-0010
SN  - 2470-0029
VL  - 98
IS  - 6
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - GEN
A1  - Perez-Cornago, Aurora
A1  - Crowe, Francesca L.
A1  - Appleby, Paul N.
A1  - Bradbury, Kathryn E.
A1  - Wood, Angela M.
A1  - Jakobsen, Marianne Uhre
A1  - Johnson, Laura
A1  - Sacerdote, Carlotta
A1  - Steur, Marinka
A1  - Weiderpass, Elisabete
A1  - Wurtz, Anne Mette L.
A1  - Kuhn, Tilman
A1  - Katzke, Verena
A1  - Trichopoulou, Antonia
A1  - Karakatsani, Anna
A1  - La Vecchia, Carlo
A1  - Masala, Giovanna
A1  - Tumino, Rosario
A1  - Panico, Salvatore
A1  - Sluijs, Ivonne
A1  - Skeie, Guri
A1  - Imaz, Liher
A1  - Petrova, Dafina
A1  - Quiros, J. Ramon
A1  - Yohar, Sandra Milena Colorado
A1  - Jakszyn, Paula
A1  - Melander, Olle
A1  - Sonestedt, Emily
A1  - Andersson, Jonas
A1  - Wennberg, Maria
A1  - Aune, Dagfinn
A1  - Riboli, Elio
A1  - Schulze, Matthias Bernd
A1  - di Angelantonio, Emanuele
A1  - Wareham, Nicholas J.
A1  - Danesh, John
A1  - Forouhi, Nita G.
A1  - Butterworth, Adam S.
A1  - Key, Timothy J.
T1  - Plant foods, dietary fibre and risk of ischaemic heart disease in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
T2  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Background:
Epidemiological evidence indicates that diets rich in plant foods are associated with a lower risk of ischaemic heart disease (IHD), but there is sparse information on fruit and vegetable subtypes and sources of dietary fibre. This study examined the associations of major plant foods, their subtypes and dietary fibre with risk of IHD in the European Prospective Investigation into Cancer and Nutrition (EPIC). 

Methods:
We conducted a prospective analysis of 490 311 men and women without a history of myocardial infarction or stroke at recruitment (12.6 years of follow-up, n cases = 8504), in 10 European countries. Dietary intake was assessed using validated questionnaires, calibrated with 24-h recalls. Multivariable Cox regressions were used to estimate hazard ratios (HR) of IHD. 

Results: 
There was a lower risk of IHD with a higher intake of fruit and vegetables combined [HR per 200 g/day higher intake 0.94, 95% confidence interval (CI): 0.90-0.99, P-trend = 0.009], and with total fruits (per 100 g/day 0.97, 0.95-1.00, P-trend = 0.021). There was no evidence for a reduced risk for fruit subtypes, except for bananas. Risk was lower with higher intakes of nuts and seeds (per 10 g/day 0.90, 0.82-0.98, Ptrend = 0.020), total fibre (per 10 g/day 0.91, 0.85-0.98, P-trend = 0.015), fruit and vegetable fibre (per 4 g/day 0.95, 0.91-0.99, P-trend = 0.022) and fruit fibre (per 2 g/day 0.97, 0.95-1.00, P-trend = 0.045). No associations were observed between vegetables, vegetables subtypes, legumes, cereals and IHD risk. 

Conclusions:
In this large prospective study, we found some small inverse associations between plant foods and IHD risk, with fruit and vegetables combined being the most strongly inversely associated with risk. Whether these small associations are causal remains unclear.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1367 
KW  - fruit
KW  - vegetables
KW  - legumes
KW  - nuts
KW  - seeds
KW  - coronary heart disease
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-560340
SN  - 1866-8372
IS  - 1
ER  - 
TY  - JOUR
A1  - Perez-Cornago, Aurora
A1  - Crowe, Francesca L.
A1  - Appleby, Paul N.
A1  - Bradbury, Kathryn E.
A1  - Wood, Angela M.
A1  - Jakobsen, Marianne Uhre
A1  - Johnson, Laura
A1  - Sacerdote, Carlotta
A1  - Steur, Marinka
A1  - Weiderpass, Elisabete
A1  - Wurtz, Anne Mette L.
A1  - Kuhn, Tilman
A1  - Katzke, Verena
A1  - Trichopoulou, Antonia
A1  - Karakatsani, Anna
A1  - La Vecchia, Carlo
A1  - Masala, Giovanna
A1  - Tumino, Rosario
A1  - Panico, Salvatore
A1  - Sluijs, Ivonne
A1  - Skeie, Guri
A1  - Imaz, Liher
A1  - Petrova, Dafina
A1  - Quiros, J. Ramon
A1  - Yohar, Sandra Milena Colorado
A1  - Jakszyn, Paula
A1  - Melander, Olle
A1  - Sonestedt, Emily
A1  - Andersson, Jonas
A1  - Wennberg, Maria
A1  - Aune, Dagfinn
A1  - Riboli, Elio
A1  - Schulze, Matthias Bernd
A1  - di Angelantonio, Emanuele
A1  - Wareham, Nicholas J.
A1  - Danesh, John
A1  - Forouhi, Nita G.
A1  - Butterworth, Adam S.
A1  - Key, Timothy J.
T1  - Plant foods, dietary fibre and risk of ischaemic heart disease in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
JF  - International journal of epidemiology
N2  - Background:
Epidemiological evidence indicates that diets rich in plant foods are associated with a lower risk of ischaemic heart disease (IHD), but there is sparse information on fruit and vegetable subtypes and sources of dietary fibre. This study examined the associations of major plant foods, their subtypes and dietary fibre with risk of IHD in the European Prospective Investigation into Cancer and Nutrition (EPIC). 

Methods:
We conducted a prospective analysis of 490 311 men and women without a history of myocardial infarction or stroke at recruitment (12.6 years of follow-up, n cases = 8504), in 10 European countries. Dietary intake was assessed using validated questionnaires, calibrated with 24-h recalls. Multivariable Cox regressions were used to estimate hazard ratios (HR) of IHD. 

Results: 
There was a lower risk of IHD with a higher intake of fruit and vegetables combined [HR per 200 g/day higher intake 0.94, 95% confidence interval (CI): 0.90-0.99, P-trend = 0.009], and with total fruits (per 100 g/day 0.97, 0.95-1.00, P-trend = 0.021). There was no evidence for a reduced risk for fruit subtypes, except for bananas. Risk was lower with higher intakes of nuts and seeds (per 10 g/day 0.90, 0.82-0.98, Ptrend = 0.020), total fibre (per 10 g/day 0.91, 0.85-0.98, P-trend = 0.015), fruit and vegetable fibre (per 4 g/day 0.95, 0.91-0.99, P-trend = 0.022) and fruit fibre (per 2 g/day 0.97, 0.95-1.00, P-trend = 0.045). No associations were observed between vegetables, vegetables subtypes, legumes, cereals and IHD risk. 

Conclusions:
In this large prospective study, we found some small inverse associations between plant foods and IHD risk, with fruit and vegetables combined being the most strongly inversely associated with risk. Whether these small associations are causal remains unclear.
KW  - fruit
KW  - vegetables
KW  - legumes
KW  - nuts
KW  - seeds
KW  - coronary heart disease
Y1  - 2021
U6  - https://doi.org/10.1093/ije/dyaa155
SN  - 0300-5771
SN  - 1464-3685
VL  - 50
IS  - 1
SP  - 212
EP  - 222
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Vaid, Akhil
A1  - Somani, Sulaiman
A1  - Russak, Adam J.
A1  - De Freitas, Jessica K.
A1  - Chaudhry, Fayzan F.
A1  - Paranjpe, Ishan
A1  - Johnson, Kipp W.
A1  - Lee, Samuel J.
A1  - Miotto, Riccardo
A1  - Richter, Felix
A1  - Zhao, Shan
A1  - Beckmann, Noam D.
A1  - Naik, Nidhi
A1  - Kia, Arash
A1  - Timsina, Prem
A1  - Lala, Anuradha
A1  - Paranjpe, Manish
A1  - Golden, Eddye
A1  - Danieletto, Matteo
A1  - Singh, Manbir
A1  - Meyer, Dara
A1  - O'Reilly, Paul F.
A1  - Huckins, Laura
A1  - Kovatch, Patricia
A1  - Finkelstein, Joseph
A1  - Freeman, Robert M.
A1  - Argulian, Edgar
A1  - Kasarskis, Andrew
A1  - Percha, Bethany
A1  - Aberg, Judith A.
A1  - Bagiella, Emilia
A1  - Horowitz, Carol R.
A1  - Murphy, Barbara
A1  - Nestler, Eric J.
A1  - Schadt, Eric E.
A1  - Cho, Judy H.
A1  - Cordon-Cardo, Carlos
A1  - Fuster, Valentin
A1  - Charney, Dennis S.
A1  - Reich, David L.
A1  - Böttinger, Erwin
A1  - Levin, Matthew A.
A1  - Narula, Jagat
A1  - Fayad, Zahi A.
A1  - Just, Allan C.
A1  - Charney, Alexander W.
A1  - Nadkarni, Girish N.
A1  - Glicksberg, Benjamin S.
T1  - Machine learning to predict mortality and critical events in a cohort of patients with COVID-19 in New York City: model development and validation
JF  - Journal of medical internet research : international scientific journal for medical research, information and communication on the internet ; JMIR
N2  - Background:
COVID-19 has infected millions of people worldwide and is responsible for several hundred thousand fatalities. The COVID-19 pandemic has necessitated thoughtful resource allocation and early identification of high-risk patients. However, effective methods to meet these needs are lacking.

Objective:
The aims of this study were to analyze the electronic health records (EHRs) of patients who tested positive for COVID-19 and were admitted to hospitals in the Mount Sinai Health System in New York City; to develop machine learning models for making predictions about the hospital course of the patients over clinically meaningful time horizons based on patient characteristics at admission; and to assess the performance of these models at multiple hospitals and time points. 

Methods:
We used Extreme Gradient Boosting (XGBoost) and baseline comparator models to predict in-hospital mortality and critical events at time windows of 3, 5, 7, and 10 days from admission. Our study population included harmonized EHR data from five hospitals in New York City for 4098 COVID-19-positive patients admitted from March 15 to May 22, 2020. The models were first trained on patients from a single hospital (n=1514) before or on May 1, externally validated on patients from four other hospitals (n=2201) before or on May 1, and prospectively validated on all patients after May 1 (n=383). Finally, we established model interpretability to identify and rank variables that drive model predictions.

Results:
Upon cross-validation, the XGBoost classifier outperformed baseline models, with an area under the receiver operating characteristic curve (AUC-ROC) for mortality of 0.89 at 3 days, 0.85 at 5 and 7 days, and 0.84 at 10 days. XGBoost also performed well for critical event prediction, with an AUC-ROC of 0.80 at 3 days, 0.79 at 5 days, 0.80 at 7 days, and 0.81 at 10 days. In external validation, XGBoost achieved an AUC-ROC of 0.88 at 3 days, 0.86 at 5 days, 0.86 at 7 days, and 0.84 at 10 days for mortality prediction. Similarly, the unimputed XGBoost model achieved an AUC-ROC of 0.78 at 3 days, 0.79 at 5 days, 0.80 at 7 days, and 0.81 at 10 days. Trends in performance on prospective validation sets were similar. At 7 days, acute kidney injury on admission, elevated LDH, tachypnea, and hyperglycemia were the strongest drivers of critical event prediction, while higher age, anion gap, and C-reactive protein were the strongest drivers of mortality prediction. 

Conclusions:
We externally and prospectively trained and validated machine learning models for mortality and critical events for patients with COVID-19 at different time horizons. These models identified at-risk patients and uncovered underlying relationships that predicted outcomes.
KW  - machine learning
KW  - COVID-19
KW  - electronic health record
KW  - TRIPOD
KW  - clinical
KW  - informatics
KW  - prediction
KW  - mortality
KW  - EHR
KW  - cohort
KW  - hospital
KW  - performance
Y1  - 2020
U6  - https://doi.org/10.2196/24018
SN  - 1439-4456
SN  - 1438-8871
VL  - 22
IS  - 11
PB  - Healthcare World
CY  - Richmond, Va.
ER  - 
TY  - JOUR
A1  - Jones, Geraint H.
A1  - Arridge, Christopher S.
A1  - Coates, Andrew J.
A1  - Lewis, Gethyn R.
A1  - Kanani, Sheila
A1  - Wellbrock, Anne
A1  - Young, David T.
A1  - Crary, Frank J.
A1  - Tokar, Robert L.
A1  - Wilson, R. J.
A1  - Hill, Thomas W.
A1  - Johnson, Robert E.
A1  - Mitchell, Donald G.
A1  - Schmidt, Jürgen
A1  - Kempf, Sascha
A1  - Beckmann, Uwe
A1  - Russell, Christopher T.
A1  - Jia, Y. D.
A1  - Dougherty, Michele K.
A1  - Waite, J. Hunter
A1  - Magee, Brian A.
T1  - Fine jet structure of electrically charged grains in Enceladus' plume
N2  - By traversing the plume erupting from high southern latitudes on Saturn's moon Enceladus, Cassini orbiter instruments can directly sample the material therein. Cassini Plasma Spectrometer, CAPS, data show that a major plume component comprises previously-undetected particles of nanometer scales and larger that bridge the mass gap between previously observed gaseous species and solid icy grains. This population is electrically charged both negative and positive, indicating that subsurface triboelectric charging, i.e., contact electrification of condensed plume material may occur through mutual collisions within vents. The electric field of Saturn's magnetosphere controls the jets' morphologies, separating particles according to mass and charge. Fine-scale structuring of these particles' spatial distribution correlates with discrete plume jets' sources, and reveals locations of other possible active regions. The observed plume population likely forms a major component of high velocity nanometer particle streams detected outside Saturn's magnetosphere.
Y1  - 2009
UR  - http://www.agu.org/journals/gl/
U6  - https://doi.org/10.1029/2009gl038284
SN  - 0094-8276
ER  - 
TY  - JOUR
A1  - van der Lubbe, H. J. L.
A1  - Krause-Nehring, J.
A1  - Junginger, A.
A1  - Garcin, Yannick
A1  - Joordens, J. C. A.
A1  - Davies, G. R.
A1  - Beck, C.
A1  - Feibel, C. S.
A1  - Johnson, T. C.
A1  - Vonhof, H. B.
T1  - Gradual or abrupt? Changes in water source of Lake Turkana (Kenya) during the African Humid Period inferred from Sr isotope ratios
JF  - Quaternary science reviews : the international multidisciplinary research and review journal
Y1  - 2017
U6  - https://doi.org/10.1016/j.quascirev.2017.08.010
SN  - 0277-3791
VL  - 174
SP  - 1
EP  - 12
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Abeysekara, A. U.
A1  - Archer, A.
A1  - Benbow, Wystan
A1  - Bird, Ralph
A1  - Brill, A.
A1  - Brose, Robert
A1  - Buchovecky, M.
A1  - Calderon-Madera, D.
A1  - Christiansen, J. L.
A1  - Cui, W.
A1  - Daniel, M. K.
A1  - Falcone, A.
A1  - Feng, Q.
A1  - Fernandez-Alonso, M.
A1  - Finley, J. P.
A1  - Fortson, Lucy
A1  - Furniss, Amy
A1  - Gent, A.
A1  - Giuri, C.
A1  - Gueta, O.
A1  - Hanna, David
A1  - Hassan, T.
A1  - Hervet, Oliver
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Johnson, Caitlin A.
A1  - Kaaret, P.
A1  - Kertzman, M.
A1  - Kieda, David
A1  - Krause, Maria
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Maier, Gernot
A1  - Moriarty, P.
A1  - Mukherjee, Reshmi
A1  - Nievas-Rosillo, M.
A1  - Ong, R. A.
A1  - Pfrang, Konstantin Johannes
A1  - Pohl, Martin
A1  - Prado, R. R.
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reynolds, P. T.
A1  - Ribeiro, D.
A1  - Richards, G. T.
A1  - Roache, E.
A1  - Rovero, A. C.
A1  - Sadeh, Iftach
A1  - Santander, M.
A1  - Sembroski, G. H.
A1  - Shahinyan, Karlen
A1  - Sushch, Iurii
A1  - Svraka, T.
A1  - Weinstein, A.
A1  - Wells, R. M.
A1  - Wilcox, Patrick
A1  - Wilhelm, Alina
A1  - Williams, David Arnold
A1  - Williamson, T. J.
A1  - Zitzer, B.
T1  - Measurement of the Extragalactic Background Light Spectral Energy Distribution with VERITAS
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - The extragalactic background light (EBL), a diffuse photon field in the optical and infrared range, is a record of radiative processes over the universe?s history. Spectral measurements of blazars at very high energies (>100 GeV) enable the reconstruction of the spectral energy distribution (SED) of the EBL, as the blazar spectra are modified by redshift- and energy-dependent interactions of the gamma-ray photons with the EBL. The spectra of 14 VERITAS-detected blazars are included in a new measurement of the EBL SED that is independent of EBL SED models. The resulting SED covers an EBL wavelength range of 0.56?56 ?m, and is in good agreement with lower limits obtained by assuming that the EBL is entirely due to radiation from cataloged galaxies.
KW  - Extragalactic astronomy
KW  - Active galactic nuclei
KW  - Diffuse radiation
KW  - Cosmology
Y1  - 2019
U6  - https://doi.org/10.3847/1538-4357/ab4817
SN  - 0004-637X
SN  - 1538-4357
VL  - 885
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  -