TY  - JOUR
A1  - Stracke, A.
A1  - Bayer, A.
A1  - Zimmermann, S.
A1  - Wendorff, Joachim Heinz
A1  - Wirges, Werner
A1  - Bauer-Gogonea, Simona
A1  - Bauer, Siegfried
A1  - Gerhard, Reimund
T1  - Relaxation behaviour of electrically induced polar orientation and of optically induced non-polar orientation in an azo-chromophore side group polymer
Y1  - 1999
SN  - 0022-3727
ER  - 
TY  - JOUR
A1  - Bauer, Joachim
A1  - Stamm, Axel
A1  - Virnich, Katharina
A1  - Wissing, Karen
A1  - Müller, Udo
A1  - Wirsching, Michael
A1  - Schaarschmidt, Uwe
T1  - Correlation between burnout syndrome and psychological and psychosomatic symptoms among teachers
N2  - Objectives: Psychosomatic disorders and symptoms that correlate with the so-called burnout syndrome turned out to be the main cause of increasing rates of premature retirement of school teachers. The aim of this study was to evaluate the relation between occupational burden and psychological strain of teachers who are still in work. Methods: A sample of 408 teachers at ten grammar schools (am: High school; German: Gymnasium) in south-western Germany was evaluated. To determine the styles of coping with occupational burden we used the measure of coping capacity questionnaire (MECCA). To analyse the psychopathological and psychosomatic symptom load we applied SCL 90 R questionnaire. Results: According to the MECCA questionnaire, 32.5% of the sample suffered from burnout (type B), 17.7% suffered severe strain (type A), 35.9% showed an unambitious (type S) and 13.8% showed a healthy-ambitious coping style (type G). Burnout was significantly higher among women, divorced teachers and teachers working part-time. As part of the MECCA, teachers were asked to rate what they regarded as the strongest factor resulting in occupational burden. Teachers indicated that, besides high numbers of pupils in one class, they regarded destructive and aggressive behaviour of pupils as the primary stress factor. According to the SCL 90 R, 20% of the sample showed a severe degree (defined as > 70 points in the SCL90R GSI) of psychological and psychosomatic symptoms. MECCA type B (burnout) correlated significantly with high psychological and psychosomatic symptom load according to the SCL90R. Conclusions: In school teachers, burnout syndrome, a construct that derived from occupational psychology and occupational medicine, is significantly correlated with psychological and psychosomatic symptoms. Teachers rate destructive and aggressive behaviour of pupils as the primary stress factor.
Y1  - 2006
UR  - http://www.springerlink.com/content/101165
U6  - https://doi.org/10.1007/s00420-005-0050-y
SN  - 0340-0131
ER  - 
TY  - JOUR
A1  - Gruden, Kristina
A1  - Hren, Matjaz
A1  - Herman, Ana
A1  - Blejec, Andrej
A1  - Albrecht, Tanja
A1  - Selbig, Joachim
A1  - Bauer, Christian G.
A1  - Schuchardt, Johannes
A1  - Or-Guil, Michal
A1  - Zupancic, Klemen
A1  - Svajger, Urban
A1  - Stabuc, Borut
A1  - Ihan, Alojz
A1  - Kopitar, Andreja Natasa
A1  - Ravnikar, Maja
A1  - Knezevic, Miomir
A1  - Rozman, Primoz
A1  - Jeras, Matjaz
T1  - A "Crossomics" study analysing variability of different components in peripheral blood of healthy caucasoid individuals
JF  - PLoS one
N2  - Background: Different immunotherapy approaches for the treatment of cancer and autoimmune diseases are being developed and tested in clinical studies worldwide. Their resulting complex experimental data should be properly evaluated, therefore reliable normal healthy control baseline values are indispensable.
 Methodology/Principal Findings: To assess intra- and inter-individual variability of various biomarkers, peripheral blood of 16 age and gender equilibrated healthy volunteers was sampled on 3 different days within a period of one month. Complex "crossomics'' analyses of plasma metabolite profiles, antibody concentrations and lymphocyte subset counts as well as whole genome expression profiling in CD4(+)T and NK cells were performed. Some of the observed age, gender and BMI dependences are in agreement with the existing knowledge, like negative correlation between sex hormone levels and age or BMI related increase in lipids and soluble sugars. Thus we can assume that the distribution of all 39.743 analysed markers is well representing the normal Caucasoid population. All lymphocyte subsets, 20% of metabolites and less than 10% of genes, were identified as highly variable in our dataset.
 Conclusions/Significance: Our study shows that the intra- individual variability was at least two-fold lower compared to the inter-individual one at all investigated levels, showing the importance of personalised medicine approach from yet another perspective.
Y1  - 2012
U6  - https://doi.org/10.1371/journal.pone.0028761
SN  - 1932-6203
VL  - 7
IS  - 1
PB  - PLoS
CY  - San Fransisco
ER  -