TY - JOUR
A1 - Abdalla, H.
A1 - Adam, R.
A1 - Aharonian, Felix A.
A1 - Benkhali, F. Ait
A1 - Angüner, Ekrem Oǧuzhan
A1 - Arcaro, C.
A1 - Armand, C.
A1 - Armstrong, T.
A1 - Ashkar, H.
A1 - Backes, M.
A1 - Baghmanyan, V.
A1 - Martins, V. Barbosa
A1 - Barnacka, A.
A1 - Barnard, M.
A1 - Becherini, Y.
A1 - Berge, D.
A1 - Bernlohr, K.
A1 - Bi, B.
A1 - Bottcher, M.
A1 - Boisson, C.
A1 - Bolmont, J.
A1 - de Lavergne, M. de Bony
A1 - Bordas, Pol
A1 - Breuhaus, M.
A1 - Brun, F.
A1 - Brun, P.
A1 - Bryan, M.
A1 - Buchele, M.
A1 - Bulik, T.
A1 - Bylund, T.
A1 - Caroff, S.
A1 - Carosi, A.
A1 - Casanova, Sabrina
A1 - Chand, T.
A1 - Chandra, S.
A1 - Chen, A.
A1 - Cotter, G.
A1 - Curylo, M.
A1 - Mbarubucyeye, J. Damascene
A1 - Davids, I. D.
A1 - Davies, J.
A1 - Deil, C.
A1 - Devin, J.
A1 - deWilt, P.
A1 - Dirson, L.
A1 - Djannati-Atai, A.
A1 - Dmytriiev, A.
A1 - Donath, A.
A1 - Doroshenko, V.
A1 - Duffy, C.
A1 - Dyks, J.
A1 - Egberts, Kathrin
A1 - Eichhorn, F.
A1 - Einecke, S.
A1 - Emery, G.
A1 - Ernenwein, J. -P.
A1 - Feijen, K.
A1 - Fegan, S.
A1 - Fiasson, A.
A1 - de Clairfontaine, G. Fichet
A1 - Fontaine, G.
A1 - Funk, S.
A1 - Fussling, Matthias
A1 - Gabici, S.
A1 - Gallant, Y. A.
A1 - Giavitto, G.
A1 - Giunti, L.
A1 - Glawion, D.
A1 - Glicenstein, J. F.
A1 - Gottschall, D.
A1 - Grondin, M. -H.
A1 - Hahn, J.
A1 - Haupt, M.
A1 - Hermann, G.
A1 - Hinton, J. A.
A1 - Hofmann, W.
A1 - Hoischen, Clemens
A1 - Holch, T. L.
A1 - Holler, M.
A1 - Horbe, M.
A1 - Horns, D.
A1 - Huber, D.
A1 - Jamrozy, M.
A1 - Jankowsky, D.
A1 - Jankowsky, F.
A1 - Jardin-Blicq, A.
A1 - Joshi, V.
A1 - Jung-Richardt, I.
A1 - Kasai, E.
A1 - Kastendieck, M. A.
A1 - Katarzynski, K.
A1 - Katz, U.
A1 - Khangulyan, D.
A1 - Khelifi, B.
A1 - Klepser, S.
A1 - Kluzniak, W.
A1 - Komin, Nu.
A1 - Konno, R.
A1 - Kosack, K.
A1 - Kostunin, D.
A1 - Kreter, M.
A1 - Lamanna, G.
A1 - Lemiere, A.
A1 - Lemoine-Goumard, M.
A1 - Lenain, J. -P.
A1 - Levy, C.
A1 - Lohse, T.
A1 - Lypova, I.
A1 - Mackey, J.
A1 - Majumdar, J.
A1 - Malyshev, D.
A1 - Malyshev, D.
A1 - Marandon, V.
A1 - Marchegiani, P.
A1 - Marcowith, Alexandre
A1 - Mares, A.
A1 - Marti-Devesa, G.
A1 - Marx, R.
A1 - Maurin, G.
A1 - Meintjes, P. J.
A1 - Meyer, M.
A1 - Mitchell, A.
A1 - Moderski, R.
A1 - Mohamed, M.
A1 - Mohrmann, L.
A1 - Montanari, A.
A1 - Moore, C.
A1 - Morris, P.
A1 - Moulin, Emmanuel
A1 - Muller, J.
A1 - Murach, T.
A1 - Nakashima, K.
A1 - Nayerhoda, A.
A1 - de Naurois, M.
A1 - Ndiyavala, H.
A1 - Niederwanger, F.
A1 - Niemiec, J.
A1 - Oakes, L.
A1 - O'Brien, Patrick
A1 - Odaka, H.
A1 - Ohm, S.
A1 - Olivera-Nieto, L.
A1 - Wilhelmi, E. de Ona
A1 - Ostrowski, M.
A1 - Oya, I.
A1 - Panter, M.
A1 - Panny, S.
A1 - Parsons, R. D.
A1 - Peron, G.
A1 - Peyaud, B.
A1 - Piel, Q.
A1 - Pita, S.
A1 - Poireau, V.
A1 - Noel, A. Priyana
A1 - Prokhorov, D. A.
A1 - Prokoph, H.
A1 - Puhlhofer, G.
A1 - Punch, M.
A1 - Quirrenbach, A.
A1 - Raab, S.
A1 - Rauth, R.
A1 - Reichherzer, P.
A1 - Reimer, A.
A1 - Reimer, O.
A1 - Remy, Q.
A1 - Renaud, M.
A1 - Rieger, F.
A1 - Rinchiuso, L.
A1 - Romoli, C.
A1 - Rowell, G.
A1 - Rudak, B.
A1 - Ruiz-Velasco, E.
A1 - Sahakian, V.
A1 - Sailer, S.
A1 - Sanchez, D. A.
A1 - Santangelo, Andrea
A1 - Sasaki, M.
A1 - Scalici, M.
A1 - Schussler, F.
A1 - Schutte, H. M.
A1 - Schwanke, U.
A1 - Schwemmer, S.
A1 - Seglar-Arroyo, M.
A1 - Senniappan, M.
A1 - Seyffert, A. S.
A1 - Shafi, N.
A1 - Shiningayamwe, K.
A1 - Simoni, R.
A1 - Sinha, A.
A1 - Sol, H.
A1 - Specovius, A.
A1 - Spencer, S.
A1 - Spir-Jacob, M.
A1 - Stawarz, L.
A1 - Sun, L.
A1 - Steenkamp, R.
A1 - Stegmann, C.
A1 - Steinmassl, S.
A1 - Steppa, C.
A1 - Takahashi, T.
A1 - Tavernier, T.
A1 - Taylor, A. M.
A1 - Terrier, R.
A1 - Tiziani, D.
A1 - Tluczykont, M.
A1 - Tomankova, L.
A1 - Trichard, C.
A1 - Tsirou, M.
A1 - Tuffs, R.
A1 - Uchiyama, Y.
A1 - van der Walt, D. J.
A1 - van Eldik, C.
A1 - van Rensburg, C.
A1 - van Soelen, B.
A1 - Vasileiadis, G.
A1 - Veh, J.
A1 - Venter, C.
A1 - Vincent, P.
A1 - Vink, J.
A1 - Volk, H. J.
A1 - Vuillaume, T.
A1 - Wadiasingh, Z.
A1 - Wagner, S. J.
A1 - Watson, J.
A1 - Werner, F.
A1 - White, R.
A1 - Wierzcholska, A.
A1 - Wong, Yu Wun
A1 - Yusafzai, A.
A1 - Zacharias, M.
A1 - Zanin, R.
A1 - Zargaryan, D.
A1 - Zdziarski, A. A.
A1 - Zech, Alraune
A1 - Zhu, S. J.
A1 - Ziegler, A.
A1 - Zorn, J.
A1 - Zouari, S.
A1 - Zywucka, N.
T1 - An extreme particle accelerator in the Galactic plane
BT - HESS J1826-130
JF - Astronomy and astrophysics : an international weekly journal
N2 - The unidentified very-high-energy (VHE; E > 0.1 TeV) gamma -ray source, HESS J1826-130, was discovered with the High Energy Stereoscopic System (HESS) in the Galactic plane. The analysis of 215 h of HESS data has revealed a steady gamma -ray flux from HESS J1826-130, which appears extended with a half-width of 0.21 degrees +/- 0.02
(stat)degrees
stat degrees +/- 0.05
(sys)degrees sys degrees . The source spectrum is best fit with either a power-law function with a spectral index Gamma = 1.78 +/- 0.10(stat) +/- 0.20(sys) and an exponential cut-off at 15.2
(+5.5)(-3.2) -3.2+5.5 TeV, or a broken power-law with Gamma (1) = 1.96 +/- 0.06(stat) +/- 0.20(sys), Gamma (2) = 3.59 +/- 0.69(stat) +/- 0.20(sys) for energies below and above E-br = 11.2 +/- 2.7 TeV, respectively. The VHE flux from HESS J1826-130 is contaminated by the extended emission of the bright, nearby pulsar wind nebula, HESS J1825-137, particularly at the low end of the energy spectrum. Leptonic scenarios for the origin of HESS J1826-130 VHE emission related to PSR J1826-1256 are confronted by our spectral and morphological analysis. In a hadronic framework, taking into account the properties of dense gas regions surrounding HESS J1826-130, the source spectrum would imply an astrophysical object capable of accelerating the parent particle population up to greater than or similar to 200 TeV. Our results are also discussed in a multiwavelength context, accounting for both the presence of nearby supernova remnants, molecular clouds, and counterparts detected in radio, X-rays, and TeV energies.
KW - ISM: supernova remnants
KW - ISM: clouds
KW - gamma rays: general
KW - gamma rays:
KW - ISM
Y1 - 2020
U6 - https://doi.org/10.1051/0004-6361/202038851
SN - 0004-6361
SN - 1432-0746
VL - 644
PB - EDP Sciences
CY - Les Ulis
ER -
TY - JOUR
A1 - Abdalla, Hassan E.
A1 - Adam, R.
A1 - Aharonian, Felix A.
A1 - Benkhali, F. Ait
A1 - Angüner, Ekrem Oǧuzhan
A1 - Arakawa, M.
A1 - Arcaro, C.
A1 - Armand, C.
A1 - Ashkar, H.
A1 - Backes, M.
A1 - Martins, V. Barbosa
A1 - Barnard, M.
A1 - Becherini, Y.
A1 - Berge, D.
A1 - Bernloehr, K.
A1 - Bissaldi, E.
A1 - Blackwell, R.
A1 - Boettcher, M.
A1 - Boisson, C.
A1 - Bolmont, J.
A1 - Bonnefoy, S.
A1 - Bregeon, J.
A1 - Breuhaus, M.
A1 - Brun, F.
A1 - Brun, P.
A1 - Bryan, M.
A1 - Buechele, M.
A1 - Bulik, T.
A1 - Bylund, T.
A1 - Capasso, M.
A1 - Caroff, S.
A1 - Carosi, A.
A1 - Casanova, Sabrina
A1 - Cerruti, M.
A1 - Chand, T.
A1 - Chandra, S.
A1 - Chen, A.
A1 - Colafrancesco, S.
A1 - Curylo, M.
A1 - Davids, I. D.
A1 - Deil, C.
A1 - Devin, J.
A1 - deWilt, P.
A1 - Dirson, L.
A1 - Djannati-Atai, A.
A1 - Dmytriiev, A.
A1 - Donath, A.
A1 - Doroshenko, V
A1 - Dyks, J.
A1 - Egberts, Kathrin
A1 - Emery, G.
A1 - Ernenwein, J-P
A1 - Eschbach, S.
A1 - Feijen, K.
A1 - Fegan, S.
A1 - Fiasson, A.
A1 - Fontaine, G.
A1 - Funk, S.
A1 - Fussling, Matthias
A1 - Gabici, S.
A1 - Gallant, Y. A.
A1 - Gate, F.
A1 - Giavitto, G.
A1 - Giunti, L.
A1 - Glawion, D.
A1 - Glicenstein, J. F.
A1 - Gottschall, D.
A1 - Grondin, M-H
A1 - Hahn, J.
A1 - Haupt, M.
A1 - Heinzelmann, G.
A1 - Henri, G.
A1 - Hermann, G.
A1 - Hinton, J. A.
A1 - Hofmann, W.
A1 - Hoischen, Clemens
A1 - Holch, T. L.
A1 - Holler, M.
A1 - Horns, D.
A1 - Huber, D.
A1 - Iwasaki, H.
A1 - Jamrozy, M.
A1 - Jankowsky, D.
A1 - Jankowsky, F.
A1 - Jardin-Blicq, A.
A1 - Jung-Richardt, I
A1 - Kastendieck, M. A.
A1 - Katarzynski, K.
A1 - Katsuragawa, M.
A1 - Katz, U.
A1 - Khangulyan, D.
A1 - Khelifi, B.
A1 - King, J.
A1 - Klepser, S.
A1 - Kluzniak, W.
A1 - Komin, Nu
A1 - Kosack, K.
A1 - Kostunin, D.
A1 - Kreter, M.
A1 - Lamanna, G.
A1 - Lemiere, A.
A1 - Lemoine-Goumard, M.
A1 - Lenain, J-P
A1 - Leser, Eva
A1 - Levy, C.
A1 - Lohse, T.
A1 - Lypova, I
A1 - Mackey, J.
A1 - Majumdar, J.
A1 - Malyshev, D.
A1 - Marandon, V
A1 - Marcowith, Alexandre
A1 - Mares, A.
A1 - Mariaud, C.
A1 - Marti-Devesa, G.
A1 - Marx, R.
A1 - Maurin, G.
A1 - Meintjes, P. J.
A1 - Mitchell, A. M. W.
A1 - Moderski, R.
A1 - Mohamed, M.
A1 - Mohrmann, L.
A1 - Moore, C.
A1 - Moulin, Emmanuel
A1 - Muller, J.
A1 - Murach, T.
A1 - Nakashima, S.
A1 - de Naurois, M.
A1 - Ndiyavala, H.
A1 - Niederwanger, F.
A1 - Niemiec, J.
A1 - Oakes, L.
A1 - Odaka, H.
A1 - Ohm, S.
A1 - Wilhelmi, E. de Ona
A1 - Ostrowski, M.
A1 - Oya, I
A1 - Panter, M.
A1 - Parsons, R. D.
A1 - Perennes, C.
A1 - Petrucci, P-O
A1 - Peyaud, B.
A1 - Piel, Q.
A1 - Pita, S.
A1 - Poireau, V
A1 - Noel, A. Priyana
A1 - Prokhorov, D. A.
A1 - Prokoph, H.
A1 - Puehlhofer, G.
A1 - Punch, M.
A1 - Quirrenbach, A.
A1 - Raab, S.
A1 - Rauth, R.
A1 - Reimer, A.
A1 - Reimer, O.
A1 - Remy, Q.
A1 - Renaud, M.
A1 - Rieger, F.
A1 - Rinchiuso, L.
A1 - Romoli, C.
A1 - Rowell, G.
A1 - Rudak, B.
A1 - Ruiz-Velasco, E.
A1 - Sahakian, V
A1 - Sailer, S.
A1 - Saito, S.
A1 - Sanchez, D. A.
A1 - Santangelo, Andrea
A1 - Sasaki, M.
A1 - Schlickeiser, R.
A1 - Schussler, F.
A1 - Schulz, A.
A1 - Schutte, H. M.
A1 - Schwanke, U.
A1 - Schwemmer, S.
A1 - Seglar-Arroyo, M.
A1 - Senniappan, M.
A1 - Seyffert, A. S.
A1 - Shafi, N.
A1 - Shiningayamwe, K.
A1 - Simoni, R.
A1 - Sinha, A.
A1 - Sol, H.
A1 - Specovius, A.
A1 - Spir-Jacob, M.
A1 - Stawarz, L.
A1 - Steenkamp, R.
A1 - Stegmann, Christian
A1 - Steppa, Constantin Beverly
A1 - Takahashi, T.
A1 - Tavernier, T.
A1 - Taylor, A. M.
A1 - Terrier, R.
A1 - Tiziani, D.
A1 - Tluczykont, M.
A1 - Trichard, C.
A1 - Tsirou, M.
A1 - Tsuji, N.
A1 - Tuffs, R.
A1 - Uchiyama, Y.
A1 - van der Walt, D. J.
A1 - van Eldik, C.
A1 - van Rensburg, C.
A1 - van Soelen, B.
A1 - Vasileiadis, G.
A1 - Veh, J.
A1 - Venter, C.
A1 - Vincent, P.
A1 - Vink, J.
A1 - Voelk, H. J.
A1 - Vuillaume, T.
A1 - Wadiasingh, Z.
A1 - Wagner, S. J.
A1 - White, R.
A1 - Wierzcholska, A.
A1 - Yang, R.
A1 - Yoneda, H.
A1 - Zacharias, M.
A1 - Zanin, R.
A1 - Zdziarski, A. A.
A1 - Zech, Alraune
A1 - Ziegler, A.
A1 - Zorn, J.
A1 - Zywucka, N.
A1 - de Palma, F.
A1 - Axelsson, M.
A1 - Roberts, O. J.
T1 - A very-high-energy component deep in the gamma-ray burst afterglow
JF - Nature : the international weekly journal of science
N2 - Gamma-ray bursts (GRBs) are brief flashes of gamma-rays and are considered to be the most energetic explosive phenomena in the Universe(1). The emission from GRBs comprises a short (typically tens of seconds) and bright prompt emission, followed by a much longer afterglow phase. During the afterglow phase, the shocked outflow-produced by the interaction between the ejected matter and the circumburst medium-slows down, and a gradual decrease in brightness is observed(2). GRBs typically emit most of their energy via.-rays with energies in the kiloelectronvolt-to-megaelectronvolt range, but a few photons with energies of tens of gigaelectronvolts have been detected by space-based instruments(3). However, the origins of such high-energy (above one gigaelectronvolt) photons and the presence of very-high-energy (more than 100 gigaelectronvolts) emission have remained elusive(4). Here we report observations of very-high-energy emission in the bright GRB 180720B deep in the GRB afterglow-ten hours after the end of the prompt emission phase, when the X-ray flux had already decayed by four orders of magnitude. Two possible explanations exist for the observed radiation: inverse Compton emission and synchrotron emission of ultrarelativistic electrons. Our observations show that the energy fluxes in the X-ray and gamma-ray range and their photon indices remain comparable to each other throughout the afterglow. This discovery places distinct constraints on the GRB environment for both emission mechanisms, with the inverse Compton explanation alleviating the particle energy requirements for the emission observed at late times. The late timing of this detection has consequences for the future observations of GRBs at the highest energies.
Y1 - 2019
U6 - https://doi.org/10.1038/s41586-019-1743-9
SN - 0028-0836
SN - 1476-4687
VL - 575
IS - 7783
SP - 464
EP - +
PB - Nature Publ. Group
CY - London
ER -
TY - JOUR
A1 - Abdalla, Hassan E.
A1 - Aharonian, Felix A.
A1 - Benkhali, F. Ait
A1 - Anguener, E. O.
A1 - Arakawa, M.
A1 - Arcaro, C.
A1 - Armand, C.
A1 - Ashkar, H.
A1 - Backes, M.
A1 - Martins, V. Barbosa
A1 - Barnard, M.
A1 - Becherini, Y.
A1 - Berge, D.
A1 - Bernloehr, K.
A1 - Blackwell, R.
A1 - Boettcher, M.
A1 - Boisson, C.
A1 - Bolmont, J.
A1 - Bonnefoy, S.
A1 - Bregeon, J.
A1 - Breuhaus, M.
A1 - Brun, F.
A1 - Brun, P.
A1 - Bryan, M.
A1 - Buechele, M.
A1 - Bulik, T.
A1 - Bylund, T.
A1 - Capasso, M.
A1 - Caroff, S.
A1 - Carosi, A.
A1 - Casanova, Sabrina
A1 - Cerruti, M.
A1 - Chakraborty, N.
A1 - Chand, T.
A1 - Chandra, S.
A1 - Chaves, R. C. G.
A1 - Chen, A.
A1 - Colafrancesco, S.
A1 - Curylo, M.
A1 - Davids, I. D.
A1 - Deil, C.
A1 - Devin, J.
A1 - de Wilt, P.
A1 - Dirson, L.
A1 - Djannati-Atai, A.
A1 - Dmytriiev, A.
A1 - Donath, A.
A1 - Doroshenko, V
A1 - Dyks, J.
A1 - Egberts, Kathrin
A1 - Emery, G.
A1 - Ernenwein, J-p
A1 - Eschbach, S.
A1 - Feijen, K.
A1 - Fegan, S.
A1 - Fiasson, A.
A1 - Fontaine, G.
A1 - Funk, S.
A1 - Fuessling, M.
A1 - Gabici, S.
A1 - Gallant, Y. A.
A1 - Gate, F.
A1 - Giavitto, G.
A1 - Glawion, D.
A1 - Glicenstein, J. F.
A1 - Gottschall, D.
A1 - Grondin, M-H
A1 - Hahn, J.
A1 - Haupt, M.
A1 - Heinzelmann, G.
A1 - Henri, G.
A1 - Hermann, G.
A1 - Hinton, James Anthony
A1 - Hofmann, W.
A1 - Hoischen, Clemens
A1 - Holch, Tim Lukas
A1 - Holler, M.
A1 - Horns, D.
A1 - Huber, D.
A1 - Iwasaki, H.
A1 - Jamrozy, M.
A1 - Jankowsky, D.
A1 - Jankowsky, F.
A1 - Jung-Richardt, I
A1 - Kastendieck, M. A.
A1 - Katarzynski, K.
A1 - Katsuragawa, M.
A1 - Katz, U.
A1 - Khangulyan, D.
A1 - Khelifi, B.
A1 - King, J.
A1 - Klepser, S.
A1 - Kluzniak, W.
A1 - Komin, Nu
A1 - Kosack, K.
A1 - Kostunin, D.
A1 - Kraus, M.
A1 - Lamanna, G.
A1 - Lau, J.
A1 - Lemiere, A.
A1 - Lemoine-Goumard, M.
A1 - Lenain, J-P
A1 - Leser, Eva
A1 - Levy, C.
A1 - Lohse, T.
A1 - Lopez-Coto, R.
A1 - Lypova, I
A1 - Mackey, J.
A1 - Majumdar, J.
A1 - Malyshev, D.
A1 - Marandon, V
A1 - Marcowith, Alexandre
A1 - Mares, A.
A1 - Mariaud, C.
A1 - Marti-Devesa, G.
A1 - Marx, R.
A1 - Maurin, G.
A1 - Meintjes, P. J.
A1 - Mitchell, A. M. W.
A1 - Moderski, R.
A1 - Mohamed, M.
A1 - Mohrmann, L.
A1 - Muller, J.
A1 - Moore, C.
A1 - Moulin, Emmanuel
A1 - Murach, T.
A1 - Nakashima, S.
A1 - de Naurois, M.
A1 - Ndiyavala, H.
A1 - Niederwanger, F.
A1 - Niemiec, J.
A1 - Oakes, L.
A1 - Odaka, H.
A1 - Ohm, S.
A1 - Wilhelmi, E. de Ona
A1 - Ostrowski, M.
A1 - Oya, I
A1 - Panter, M.
A1 - Parsons, R. D.
A1 - Perennes, C.
A1 - Petrucci, P-O
A1 - Peyaud, B.
A1 - Piel, Q.
A1 - Pita, S.
A1 - Poireau, V
A1 - Noel, A. Priyana
A1 - Prokhorov, D. A.
A1 - Prokoph, H.
A1 - Puehlhofer, G.
A1 - Punch, M.
A1 - Quirrenbach, A.
A1 - Raab, S.
A1 - Rauth, R.
A1 - Reimer, A.
A1 - Reimer, O.
A1 - Remy, Q.
A1 - Renaud, M.
A1 - Rieger, F.
A1 - Rinchiuso, L.
A1 - Romoli, C.
A1 - Rowell, G.
A1 - Rudak, B.
A1 - Ruiz-Velasco, E.
A1 - Sahakian, V
A1 - Saito, S.
A1 - Sanchez, David M.
A1 - Santangelo, Andrea
A1 - Sasaki, M.
A1 - Schlickeiser, R.
A1 - Schussler, F.
A1 - Schulz, A.
A1 - Schutte, H.
A1 - Schwanke, U.
A1 - Schwemmer, S.
A1 - Seglar-Arroyo, M.
A1 - Senniappan, M.
A1 - Seyffert, A. S.
A1 - Shafi, N.
A1 - Shiningayamwe, K.
A1 - Simoni, R.
A1 - Sinha, A.
A1 - Sol, H.
A1 - Specovius, A.
A1 - Spir-Jacob, M.
A1 - Stawarz, L.
A1 - Steenkamp, R.
A1 - Stegmann, Christian
A1 - Steppa, Constantin Beverly
A1 - Takahashi, T.
A1 - Tavernier, T.
A1 - Taylor, A. M.
A1 - Terrier, R.
A1 - Tiziani, D.
A1 - Tluczykont, M.
A1 - Trichard, C.
A1 - Tsirou, M.
A1 - Tsuji, N.
A1 - Tuffs, R.
A1 - Uchiyama, Y.
A1 - van der Walt, D. J.
A1 - van Eldik, C.
A1 - van Rensburg, C.
A1 - van Soelen, B.
A1 - Vasileiadis, G.
A1 - Veh, J.
A1 - Venter, C.
A1 - Vincent, P.
A1 - Vink, J.
A1 - Voisin, F.
A1 - Voelk, H. J.
A1 - Vuillaume, T.
A1 - Wadiasingh, Z.
A1 - Wagner, S. J.
A1 - White, R.
A1 - Wierzcholska, A.
A1 - Yang, R.
A1 - Yoneda, H.
A1 - Zacharias, M.
A1 - Zanin, R.
A1 - Zdziarski, A. A.
A1 - Zech, Alraune
A1 - Ziegler, A.
A1 - Zorn, J.
A1 - Zywucka, N.
A1 - Maxted, N.
T1 - Upper limits on very-high-energy gamma-ray emission from core-collapse supernovae observed with H.E.S.S.
JF - Astronomy and astrophysics : an international weekly journal
N2 - Young core-collapse supernovae with dense-wind progenitors may be able to accelerate cosmic-ray hadrons beyond the knee of the cosmic-ray spectrum, and this may result in measurable gamma-ray emission. We searched for gamma-ray emission from ten super- novae observed with the High Energy Stereoscopic System (H.E.S.S.) within a year of the supernova event. Nine supernovae were observed serendipitously in the H.E.S.S. data collected between December 2003 and December 2014, with exposure times ranging from 1.4 to 53 h. In addition we observed SN 2016adj as a target of opportunity in February 2016 for 13 h. No significant gamma-ray emission has been detected for any of the objects, and upper limits on the >1 TeV gamma-ray flux of the order of similar to 10(-13) cm(-)(2)s(-1) are established, corresponding to upper limits on the luminosities in the range similar to 2 x 10(39) to similar to 1 x 10(42) erg s(-1). These values are used to place model-dependent constraints on the mass-loss rates of the progenitor stars, implying upper limits between similar to 2 x 10(-5) and similar to 2 x 10(-3) M-circle dot yr(-1) under reasonable assumptions on the particle acceleration parameters.
KW - gamma rays: general
KW - supernovae: general
KW - cosmic rays
Y1 - 2019
U6 - https://doi.org/10.1051/0004-6361/201935242
SN - 1432-0746
VL - 626
PB - EDP Sciences
CY - Les Ulis
ER -
TY - JOUR
A1 - Abdalla, Hassan E.
A1 - Adam, R.
A1 - Aharonian, Felix A.
A1 - Benkhali, F. Ait
A1 - Angüner, Ekrem Oǧuzhan
A1 - Arakawa, M.
A1 - Arcaro, C.
A1 - Armand, C.
A1 - Ashkar, H.
A1 - Backes, M.
A1 - Martins, V. Barbosa
A1 - Barnard, M.
A1 - Becherini, Y.
A1 - Berge, D.
A1 - Bernloehr, K.
A1 - Blackwell, R.
A1 - Böttcher, M.
A1 - Boisson, C.
A1 - Bolmont, J.
A1 - Bonnefoy, S.
A1 - Bregeon, J.
A1 - Breuhaus, M.
A1 - Brun, F.
A1 - Brun, P.
A1 - Bryan, M.
A1 - Büchele, M.
A1 - Bulik, T.
A1 - Bylund, T.
A1 - Capasso, M.
A1 - Caroff, S.
A1 - Carosi, A.
A1 - Casanova, Sabrina
A1 - Cerruti, M.
A1 - Chand, T.
A1 - Chandra, S.
A1 - Chen, A.
A1 - Colafrancesco, S.
A1 - Curylo, M.
A1 - Davids, I. D.
A1 - Deil, C.
A1 - Devin, J.
A1 - DeWilt, P.
A1 - Dirson, L.
A1 - Djannati-Ata, A.
A1 - Dmytriiev, A.
A1 - Donath, A.
A1 - Doroshenko, V
A1 - Dyks, J.
A1 - Egberts, Kathrin
A1 - Emery, G.
A1 - Ernenwein, J-P
A1 - Eschbach, S.
A1 - Feijen, K.
A1 - Fegan, S.
A1 - Fiasson, A.
A1 - Fontaine, G.
A1 - Funk, S.
A1 - Füßling, Matthias
A1 - Gabici, S.
A1 - Gallant, Y. A.
A1 - Gate, F.
A1 - Giavitto, G.
A1 - Glawion, D.
A1 - Glicenstein, J. F.
A1 - Gottschall, D.
A1 - Grondin, M-H
A1 - Hahn, J.
A1 - Haupt, M.
A1 - Heinzelmann, G.
A1 - Henri, G.
A1 - Hermann, G.
A1 - Hinton, James Anthony
A1 - Hofmann, W.
A1 - Hoischen, Clemens
A1 - Holch, Tim Lukas
A1 - Holler, M.
A1 - Horns, D.
A1 - Huber, D.
A1 - Iwasaki, H.
A1 - Jamrozy, M.
A1 - Jankowsky, D.
A1 - Jankowsky, F.
A1 - Jardin-Blicq, A.
A1 - Jung-Richardt, I
A1 - Kastendieck, M. A.
A1 - Katarzynski, K.
A1 - Katsuragawa, M.
A1 - Katz, U.
A1 - Khangulyan, D.
A1 - Khelifi, B.
A1 - King, J.
A1 - Klepser, S.
A1 - Kluzniak, W.
A1 - Komin, Nu
A1 - Kosack, K.
A1 - Kostunin, D.
A1 - Kraus, M.
A1 - Lamanna, G.
A1 - Lau, J.
A1 - Lemiere, A.
A1 - Lemoine-Goumard, M.
A1 - Lenain, J-P
A1 - Leser, Eva
A1 - Levy, C.
A1 - Lohse, T.
A1 - Lypova, I
A1 - Mackey, J.
A1 - Majumdar, J.
A1 - Malyshev, D.
A1 - Marandon, V
A1 - Marcowith, Alexandre
A1 - Mares, A.
A1 - Mariaud, C.
A1 - Marti-Devesa, G.
A1 - Marx, R.
A1 - Maurin, G.
A1 - Meintjes, P. J.
A1 - Mitchell, A. M. W.
A1 - Moderski, R.
A1 - Mohamed, M.
A1 - Mohrmann, L.
A1 - Moore, C.
A1 - Moulin, Emmanuel
A1 - Muller, J.
A1 - Murach, T.
A1 - Nakashima, S.
A1 - de Naurois, M.
A1 - Ndiyavala, H.
A1 - Niederwanger, F.
A1 - Niemiec, J.
A1 - Oakes, L.
A1 - Odaka, H.
A1 - Ohm, S.
A1 - Wilhelmi, E. de Ona
A1 - Ostrowski, M.
A1 - Oya, I
A1 - Panter, M.
A1 - Parsons, R. D.
A1 - Perennes, C.
A1 - Petrucci, P-O
A1 - Peyaud, B.
A1 - Piel, Q.
A1 - Pita, S.
A1 - Poireau, V
A1 - Priyana Noel, A.
A1 - Prokhorov, D. A.
A1 - Prokoph, H.
A1 - Pühlhofer, G.
A1 - Punch, M.
A1 - Quirrenbach, A.
A1 - Raab, S.
A1 - Rauth, R.
A1 - Reimer, A.
A1 - Reimer, O.
A1 - Remy, Q.
A1 - Renaud, M.
A1 - Rieger, F.
A1 - Rinchiuso, L.
A1 - Romoli, C.
A1 - Rowell, G.
A1 - Rudak, B.
A1 - Ruiz-Velasco, E.
A1 - Sahakian, V
A1 - Saito, S.
A1 - Sanchez, David M.
A1 - Santangelo, Andrea
A1 - Sasaki, M.
A1 - Schlickeiser, R.
A1 - Schüssler, F.
A1 - Schulz, A.
A1 - Schutte, H.
A1 - Schwanke, U.
A1 - Schwemmer, S.
A1 - Seglar-Arroyo, M.
A1 - Senniappan, M.
A1 - Seyffert, A. S.
A1 - Shafi, N.
A1 - Shiningayamwe, K.
A1 - Simoni, R.
A1 - Sinha, A.
A1 - Sol, H.
A1 - Specovius, A.
A1 - Spir-Jacob, M.
A1 - Stawarz, L.
A1 - Steenkamp, R.
A1 - Stegmann, Christian
A1 - Steppa, Constantin Beverly
A1 - Takahashi, T.
A1 - Tavernier, T.
A1 - Taylor, A. M.
A1 - Terrier, R.
A1 - Tiziani, D.
A1 - Tluczykont, M.
A1 - Trichard, C.
A1 - Tsirou, M.
A1 - Tsuji, N.
A1 - Tuffs, R.
A1 - Uchiyama, Y.
A1 - van Der Walt, D. J.
A1 - van Eldik, C.
A1 - van Rensburg, C.
A1 - van Soelen, B.
A1 - Vasileiadis, G.
A1 - Veh, J.
A1 - Venter, C.
A1 - Vincent, P.
A1 - Vink, J.
A1 - Voisin, F.
A1 - Voelk, H. J.
A1 - Vuillaume, T.
A1 - Wadiasingh, Z.
A1 - Wagner, S. J.
A1 - White, R.
A1 - Wierzcholska, A.
A1 - Yang, R.
A1 - Yoneda, H.
A1 - Zacharias, Michael
A1 - Zanin, R.
A1 - Zdziarski, A. A.
A1 - Zech, Alraune
A1 - Ziegler, A.
A1 - Zorn, J.
A1 - Zywucka, N.
A1 - Meyer, M.
T1 - Constraints on the emission region of 3C 279 during strong flares in 2014 and 2015 through VHE gamma-ray observations with HESS
JF - Astronomy and astrophysics : an international weekly journal
N2 - The flat spectrum radio quasar 3C 279 is known to exhibit pronounced variability in the high-energy (100MeV < E < 100 GeV) gamma-ray band, which is continuously monitored with Fermi-LAT. During two periods of high activity in April 2014 and June 2015 target-of-opportunity observations were undertaken with the High Energy Stereoscopic System (H.E.S.S.) in the very-high-energy (VHE, E > 100 GeV) gamma-ray domain. While the observation in 2014 provides an upper limit, the observation in 2015 results in a signal with 8 : 7 sigma significance above an energy threshold of 66 GeV. No VHE variability was detected during the 2015 observations. The VHE photon spectrum is soft and described by a power-law index of 4.2 +/- 0.3. The H.E.S.S. data along with a detailed and contemporaneous multiwavelength data set provide constraints on the physical parameters of the emission region. The minimum distance of the emission region from the central black hole was estimated using two plausible geometries of the broad-line region and three potential intrinsic spectra. The emission region is confidently placed at r greater than or similar to 1 : 7 X 1017 cm from the black hole, that is beyond the assumed distance of the broad-line region. Time-dependent leptonic and lepto-hadronic one-zone models were used to describe the evolution of the 2015 flare. Neither model can fully reproduce the observations, despite testing various parameter sets. Furthermore, the H.E.S.S. data were used to derive constraints on Lorentz invariance violation given the large redshift of 3C 279.
KW - radiation mechanisms: non-thermal
KW - quasars: individual: 3C 279
KW - galaxies: active
KW - relativistic processes
Y1 - 2019
U6 - https://doi.org/10.1051/0004-6361/201935704
SN - 1432-0746
VL - 627
PB - EDP Sciences
CY - Les Ulis
ER -
TY - JOUR
A1 - Warrington, Nicole
A1 - Beaumont, Robin
A1 - Horikoshi, Momoko
A1 - Day, Felix R.
A1 - Helgeland, Øyvind
A1 - Laurin, Charles
A1 - Bacelis, Jonas
A1 - Peng, Shouneng
A1 - Hao, Ke
A1 - Feenstra, Bjarke
A1 - Wood, Andrew R.
A1 - Mahajan, Anubha
A1 - Tyrrell, Jessica
A1 - Robertson, Neil R.
A1 - Rayner, N. William
A1 - Qiao, Zhen
A1 - Moen, Gunn-Helen
A1 - Vaudel, Marc
A1 - Marsit, Carmen
A1 - Chen, Jia
A1 - Nodzenski, Michael
A1 - Schnurr, Theresia M.
A1 - Zafarmand, Mohammad Hadi
A1 - Bradfield, Jonathan P.
A1 - Grarup, Niels
A1 - Kooijman, Marjolein N.
A1 - Li-Gao, Ruifang
A1 - Geller, Frank
A1 - Ahluwalia, Tarunveer Singh
A1 - Paternoster, Lavinia
A1 - Rueedi, Rico
A1 - Huikari, Ville
A1 - Hottenga, Jouke-Jan
A1 - Lyytikäinen, Leo-Pekka
A1 - Cavadino, Alana
A1 - Metrustry, Sarah
A1 - Cousminer, Diana L.
A1 - Wu, Ying
A1 - Thiering, Elisabeth Paula
A1 - Wang, Carol A.
A1 - Have, Christian Theil
A1 - Vilor-Tejedor, Natalia
A1 - Joshi, Peter K.
A1 - Painter, Jodie N.
A1 - Ntalla, Ioanna
A1 - Myhre, Ronny
A1 - Pitkänen, Niina
A1 - van Leeuwen, Elisabeth M.
A1 - Joro, Raimo
A1 - Lagou, Vasiliki
A1 - Richmond, Rebecca C.
A1 - Espinosa, Ana
A1 - Barton, Sheila J.
A1 - Inskip, Hazel M.
A1 - Holloway, John W.
A1 - Santa-Marina, Loreto
A1 - Estivill, Xavier
A1 - Ang, Wei
A1 - Marsh, Julie A.
A1 - Reichetzeder, Christoph
A1 - Marullo, Letizia
A1 - Hocher, Berthold
A1 - Lunetta, Kathryn L.
A1 - Murabito, Joanne M.
A1 - Relton, Caroline L.
A1 - Kogevinas, Manolis
A1 - Chatzi, Leda
A1 - Allard, Catherine
A1 - Bouchard, Luigi
A1 - Hivert, Marie-France
A1 - Zhang, Ge
A1 - Muglia, Louis J.
A1 - Heikkinen, Jani
A1 - Morgen, Camilla S.
A1 - van Kampen, Antoine H. C.
A1 - van Schaik, Barbera D. C.
A1 - Mentch, Frank D.
A1 - Langenberg, Claudia
A1 - Scott, Robert A.
A1 - Zhao, Jing Hua
A1 - Hemani, Gibran
A1 - Ring, Susan M.
A1 - Bennett, Amanda J.
A1 - Gaulton, Kyle J.
A1 - Fernandez-Tajes, Juan
A1 - van Zuydam, Natalie R.
A1 - Medina-Gomez, Carolina
A1 - de Haan, Hugoline G.
A1 - Rosendaal, Frits R.
A1 - Kutalik, Zoltán
A1 - Marques-Vidal, Pedro
A1 - Das, Shikta
A1 - Willemsen, Gonneke
A1 - Mbarek, Hamdi
A1 - Müller-Nurasyid, Martina
A1 - Standl, Marie
A1 - Appel, Emil V. R.
A1 - Fonvig, Cilius Esmann
A1 - Trier, Caecilie
A1 - van Beijsterveldt, Catharina E. M.
A1 - Murcia, Mario
A1 - Bustamante, Mariona
A1 - Bonàs-Guarch, Sílvia
A1 - Hougaard, David M.
A1 - Mercader, Josep M.
A1 - Linneberg, Allan
A1 - Schraut, Katharina E.
A1 - Lind, Penelope A.
A1 - Medland, Sarah Elizabeth
A1 - Shields, Beverley M.
A1 - Knight, Bridget A.
A1 - Chai, Jin-Fang
A1 - Panoutsopoulou, Kalliope
A1 - Bartels, Meike
A1 - Sánchez, Friman
A1 - Stokholm, Jakob
A1 - Torrents, David
A1 - Vinding, Rebecca K.
A1 - Willems, Sara M.
A1 - Atalay, Mustafa
A1 - Chawes, Bo L.
A1 - Kovacs, Peter
A1 - Prokopenko, Inga
A1 - Tuke, Marcus A.
A1 - Yaghootkar, Hanieh
A1 - Ruth, Katherine S.
A1 - Jones, Samuel E.
A1 - Loh, Po-Ru
A1 - Murray, Anna
A1 - Weedon, Michael N.
A1 - Tönjes, Anke
A1 - Stumvoll, Michael
A1 - Michaelsen, Kim Fleischer
A1 - Eloranta, Aino-Maija
A1 - Lakka, Timo A.
A1 - van Duijn, Cornelia M.
A1 - Kiess, Wieland
A1 - Koerner, Antje
A1 - Niinikoski, Harri
A1 - Pahkala, Katja
A1 - Raitakari, Olli T.
A1 - Jacobsson, Bo
A1 - Zeggini, Eleftheria
A1 - Dedoussis, George V.
A1 - Teo, Yik-Ying
A1 - Saw, Seang-Mei
A1 - Montgomery, Grant W.
A1 - Campbell, Harry
A1 - Wilson, James F.
A1 - Vrijkotte, Tanja G. M.
A1 - Vrijheid, Martine
A1 - de Geus, Eco J. C. N.
A1 - Hayes, M. Geoffrey
A1 - Kadarmideen, Haja N.
A1 - Holm, Jens-Christian
A1 - Beilin, Lawrence J.
A1 - Pennell, Craig E.
A1 - Heinrich, Joachim
A1 - Adair, Linda S.
A1 - Borja, Judith B.
A1 - Mohlke, Karen L.
A1 - Eriksson, Johan G.
A1 - Widen, Elisabeth E.
A1 - Hattersley, Andrew T.
A1 - Spector, Tim D.
A1 - Kaehoenen, Mika
A1 - Viikari, Jorma S.
A1 - Lehtimaeki, Terho
A1 - Boomsma, Dorret I.
A1 - Sebert, Sylvain
A1 - Vollenweider, Peter
A1 - Sorensen, Thorkild I. A.
A1 - Bisgaard, Hans
A1 - Bonnelykke, Klaus
A1 - Murray, Jeffrey C.
A1 - Melbye, Mads
A1 - Nohr, Ellen A.
A1 - Mook-Kanamori, Dennis O.
A1 - Rivadeneira, Fernando
A1 - Hofman, Albert
A1 - Felix, Janine F.
A1 - Jaddoe, Vincent W. V.
A1 - Hansen, Torben
A1 - Pisinger, Charlotta
A1 - Vaag, Allan A.
A1 - Pedersen, Oluf
A1 - Uitterlinden, Andre G.
A1 - Jarvelin, Marjo-Riitta
A1 - Power, Christine
A1 - Hypponen, Elina
A1 - Scholtens, Denise M.
A1 - Lowe, William L.
A1 - Smith, George Davey
A1 - Timpson, Nicholas J.
A1 - Morris, Andrew P.
A1 - Wareham, Nicholas J.
A1 - Hakonarson, Hakon
A1 - Grant, Struan F. A.
A1 - Frayling, Timothy M.
A1 - Lawlor, Debbie A.
A1 - Njolstad, Pal R.
A1 - Johansson, Stefan
A1 - Ong, Ken K.
A1 - McCarthy, Mark I.
A1 - Perry, John R. B.
A1 - Evans, David M.
A1 - Freathy, Rachel M.
T1 - Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
JF - Nature genetics
N2 - Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). We used structural equation modeling to decompose the contributions of direct fetal and indirect maternal genetic effects, then applied Mendelian randomization to illuminate causal pathways. For example, both indirect maternal and direct fetal genetic effects drive the observational relationship between lower birth weight and higher later blood pressure: maternal blood pressure-raising alleles reduce offspring birth weight, but only direct fetal effects of these alleles, once inherited, increase later offspring blood pressure. Using maternal birth weight-lowering genotypes to proxy for an adverse intrauterine environment provided no evidence that it causally raises offspring blood pressure, indicating that the inverse birth weight-blood pressure association is attributable to genetic effects, and not to intrauterine programming.
Y1 - 2019
SN - 1061-4036
SN - 1546-1718
VL - 51
IS - 5
SP - 804
EP - +
PB - Nature Publ. Group
CY - New York
ER -
TY - JOUR
A1 - Aarts, Alexander A.
A1 - Anderson, Joanna E.
A1 - Anderson, Christopher J.
A1 - Attridge, Peter R.
A1 - Attwood, Angela
A1 - Axt, Jordan
A1 - Babel, Molly
A1 - Bahnik, Stepan
A1 - Baranski, Erica
A1 - Barnett-Cowan, Michael
A1 - Bartmess, Elizabeth
A1 - Beer, Jennifer
A1 - Bell, Raoul
A1 - Bentley, Heather
A1 - Beyan, Leah
A1 - Binion, Grace
A1 - Borsboom, Denny
A1 - Bosch, Annick
A1 - Bosco, Frank A.
A1 - Bowman, Sara D.
A1 - Brandt, Mark J.
A1 - Braswell, Erin
A1 - Brohmer, Hilmar
A1 - Brown, Benjamin T.
A1 - Brown, Kristina
A1 - Bruening, Jovita
A1 - Calhoun-Sauls, Ann
A1 - Callahan, Shannon P.
A1 - Chagnon, Elizabeth
A1 - Chandler, Jesse
A1 - Chartier, Christopher R.
A1 - Cheung, Felix
A1 - Christopherson, Cody D.
A1 - Cillessen, Linda
A1 - Clay, Russ
A1 - Cleary, Hayley
A1 - Cloud, Mark D.
A1 - Cohn, Michael
A1 - Cohoon, Johanna
A1 - Columbus, Simon
A1 - Cordes, Andreas
A1 - Costantini, Giulio
A1 - Alvarez, Leslie D. Cramblet
A1 - Cremata, Ed
A1 - Crusius, Jan
A1 - DeCoster, Jamie
A1 - DeGaetano, Michelle A.
A1 - Della Penna, Nicolas
A1 - den Bezemer, Bobby
A1 - Deserno, Marie K.
A1 - Devitt, Olivia
A1 - Dewitte, Laura
A1 - Dobolyi, David G.
A1 - Dodson, Geneva T.
A1 - Donnellan, M. Brent
A1 - Donohue, Ryan
A1 - Dore, Rebecca A.
A1 - Dorrough, Angela
A1 - Dreber, Anna
A1 - Dugas, Michelle
A1 - Dunn, Elizabeth W.
A1 - Easey, Kayleigh
A1 - Eboigbe, Sylvia
A1 - Eggleston, Casey
A1 - Embley, Jo
A1 - Epskamp, Sacha
A1 - Errington, Timothy M.
A1 - Estel, Vivien
A1 - Farach, Frank J.
A1 - Feather, Jenelle
A1 - Fedor, Anna
A1 - Fernandez-Castilla, Belen
A1 - Fiedler, Susann
A1 - Field, James G.
A1 - Fitneva, Stanka A.
A1 - Flagan, Taru
A1 - Forest, Amanda L.
A1 - Forsell, Eskil
A1 - Foster, Joshua D.
A1 - Frank, Michael C.
A1 - Frazier, Rebecca S.
A1 - Fuchs, Heather
A1 - Gable, Philip
A1 - Galak, Jeff
A1 - Galliani, Elisa Maria
A1 - Gampa, Anup
A1 - Garcia, Sara
A1 - Gazarian, Douglas
A1 - Gilbert, Elizabeth
A1 - Giner-Sorolla, Roger
A1 - Glöckner, Andreas
A1 - Göllner, Lars
A1 - Goh, Jin X.
A1 - Goldberg, Rebecca
A1 - Goodbourn, Patrick T.
A1 - Gordon-McKeon, Shauna
A1 - Gorges, Bryan
A1 - Gorges, Jessie
A1 - Goss, Justin
A1 - Graham, Jesse
A1 - Grange, James A.
A1 - Gray, Jeremy
A1 - Hartgerink, Chris
A1 - Hartshorne, Joshua
A1 - Hasselman, Fred
A1 - Hayes, Timothy
A1 - Heikensten, Emma
A1 - Henninger, Felix
A1 - Hodsoll, John
A1 - Holubar, Taylor
A1 - Hoogendoorn, Gea
A1 - Humphries, Denise J.
A1 - Hung, Cathy O. -Y.
A1 - Immelman, Nathali
A1 - Irsik, Vanessa C.
A1 - Jahn, Georg
A1 - Jaekel, Frank
A1 - Jekel, Marc
A1 - Johannesson, Magnus
A1 - Johnson, Larissa G.
A1 - Johnson, David J.
A1 - Johnson, Kate M.
A1 - Johnston, William J.
A1 - Jonas, Kai
A1 - Joy-Gaba, Jennifer A.
A1 - Kappes, Heather Barry
A1 - Kelso, Kim
A1 - Kidwell, Mallory C.
A1 - Kim, Seung Kyung
A1 - Kirkhart, Matthew
A1 - Kleinberg, Bennett
A1 - Knezevic, Goran
A1 - Kolorz, Franziska Maria
A1 - Kossakowski, Jolanda J.
A1 - Krause, Robert Wilhelm
A1 - Krijnen, Job
A1 - Kuhlmann, Tim
A1 - Kunkels, Yoram K.
A1 - Kyc, Megan M.
A1 - Lai, Calvin K.
A1 - Laique, Aamir
A1 - Lakens, Daniel
A1 - Lane, Kristin A.
A1 - Lassetter, Bethany
A1 - Lazarevic, Ljiljana B.
A1 - LeBel, Etienne P.
A1 - Lee, Key Jung
A1 - Lee, Minha
A1 - Lemm, Kristi
A1 - Levitan, Carmel A.
A1 - Lewis, Melissa
A1 - Lin, Lin
A1 - Lin, Stephanie
A1 - Lippold, Matthias
A1 - Loureiro, Darren
A1 - Luteijn, Ilse
A1 - Mackinnon, Sean
A1 - Mainard, Heather N.
A1 - Marigold, Denise C.
A1 - Martin, Daniel P.
A1 - Martinez, Tylar
A1 - Masicampo, E. J.
A1 - Matacotta, Josh
A1 - Mathur, Maya
A1 - May, Michael
A1 - Mechin, Nicole
A1 - Mehta, Pranjal
A1 - Meixner, Johannes
A1 - Melinger, Alissa
A1 - Miller, Jeremy K.
A1 - Miller, Mallorie
A1 - Moore, Katherine
A1 - Möschl, Marcus
A1 - Motyl, Matt
A1 - Müller, Stephanie M.
A1 - Munafo, Marcus
A1 - Neijenhuijs, Koen I.
A1 - Nervi, Taylor
A1 - Nicolas, Gandalf
A1 - Nilsonne, Gustav
A1 - Nosek, Brian A.
A1 - Nuijten, Michele B.
A1 - Olsson, Catherine
A1 - Osborne, Colleen
A1 - Ostkamp, Lutz
A1 - Pavel, Misha
A1 - Penton-Voak, Ian S.
A1 - Perna, Olivia
A1 - Pernet, Cyril
A1 - Perugini, Marco
A1 - Pipitone, R. Nathan
A1 - Pitts, Michael
A1 - Plessow, Franziska
A1 - Prenoveau, Jason M.
A1 - Rahal, Rima-Maria
A1 - Ratliff, Kate A.
A1 - Reinhard, David
A1 - Renkewitz, Frank
A1 - Ricker, Ashley A.
A1 - Rigney, Anastasia
A1 - Rivers, Andrew M.
A1 - Roebke, Mark
A1 - Rutchick, Abraham M.
A1 - Ryan, Robert S.
A1 - Sahin, Onur
A1 - Saide, Anondah
A1 - Sandstrom, Gillian M.
A1 - Santos, David
A1 - Saxe, Rebecca
A1 - Schlegelmilch, Rene
A1 - Schmidt, Kathleen
A1 - Scholz, Sabine
A1 - Seibel, Larissa
A1 - Selterman, Dylan Faulkner
A1 - Shaki, Samuel
A1 - Simpson, William B.
A1 - Sinclair, H. Colleen
A1 - Skorinko, Jeanine L. M.
A1 - Slowik, Agnieszka
A1 - Snyder, Joel S.
A1 - Soderberg, Courtney
A1 - Sonnleitner, Carina
A1 - Spencer, Nick
A1 - Spies, Jeffrey R.
A1 - Steegen, Sara
A1 - Stieger, Stefan
A1 - Strohminger, Nina
A1 - Sullivan, Gavin B.
A1 - Talhelm, Thomas
A1 - Tapia, Megan
A1 - te Dorsthorst, Anniek
A1 - Thomae, Manuela
A1 - Thomas, Sarah L.
A1 - Tio, Pia
A1 - Traets, Frits
A1 - Tsang, Steve
A1 - Tuerlinckx, Francis
A1 - Turchan, Paul
A1 - Valasek, Milan
A1 - Van Aert, Robbie
A1 - van Assen, Marcel
A1 - van Bork, Riet
A1 - van de Ven, Mathijs
A1 - van den Bergh, Don
A1 - van der Hulst, Marije
A1 - van Dooren, Roel
A1 - van Doorn, Johnny
A1 - van Renswoude, Daan R.
A1 - van Rijn, Hedderik
A1 - Vanpaemel, Wolf
A1 - Echeverria, Alejandro Vasquez
A1 - Vazquez, Melissa
A1 - Velez, Natalia
A1 - Vermue, Marieke
A1 - Verschoor, Mark
A1 - Vianello, Michelangelo
A1 - Voracek, Martin
A1 - Vuu, Gina
A1 - Wagenmakers, Eric-Jan
A1 - Weerdmeester, Joanneke
A1 - Welsh, Ashlee
A1 - Westgate, Erin C.
A1 - Wissink, Joeri
A1 - Wood, Michael
A1 - Woods, Andy
A1 - Wright, Emily
A1 - Wu, Sining
A1 - Zeelenberg, Marcel
A1 - Zuni, Kellylynn
T1 - Estimating the reproducibility of psychological science
JF - Science
N2 - Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams.
Y1 - 2015
U6 - https://doi.org/10.1126/science.aac4716
SN - 1095-9203
SN - 0036-8075
VL - 349
IS - 6251
PB - American Assoc. for the Advancement of Science
CY - Washington
ER -
TY - JOUR
A1 - Taran, Michail N.
A1 - Nunez Valdez, Maribel
A1 - Efthimiopoulos, Ilias
A1 - Müller, J.
A1 - Reichmann, Hans-Josef
A1 - Wilke, Max
A1 - Koch-Müller, Monika
T1 - Spectroscopic and ab initio studies of the pressure-induced Fe2+ high-spin-to-low-spin electronic transition in natural triphylite-lithiophilite
JF - Physics and Chemistry of Minerals
N2 - Using optical absorption and Raman spectroscopic measurements, in conjunction with the first-principles calculations, a pressure-induced high-spin (HS)-to-low-spin (LS) state electronic transition of Fe2+ (M2-octahedral site) was resolved around 76-80GPa in a natural triphylite-lithiophilite sample with chemical composition (LiFe0.7082+Mn0.292PO4)-Li-M1-Fe-M2 (theoretical composition (LiFe0.52+Mn0.5PO4)-Li-M1-Fe-M2). The optical absorption spectra at ambient conditions consist of a broad doublet band with two constituents (1) (similar to 9330cm(-1)) and (2) (similar to 7110cm(-1)), resulting from the electronic spin-allowed transition (T2gEg)-T-5-E-5 of octahedral (HSFe2+)-Fe-M2. Both (1) and (2) bands shift non-linearly with pressure to higher energies up to similar to 55GPa. In the optical absorption spectrum measured at similar to 81GPa, the aforementioned HS-related bands disappear, whereas a new broadband with an intensity maximum close to 16,360cm(-1) appears, superimposed on the tail of the high-energy ligand-to-metal O2-Fe2+ charge-transfer absorption edge. We assign this new band to the electronic spin-allowed dd-transition (1)A(1g)(1)T(1g) of LS Fe2+ in octahedral coordination. The high-pressure Raman spectra evidence the Fe2+ HS-to-LS transition mainly from the abrupt shift of the P-O symmetric stretching modes to lower frequencies at similar to 76GPa, the highest pressure achieved in the Raman spectroscopic experiments. Calculations indicated that the presence of Mn-M2(2+) simply shifts the isostructural HS-to-LS transition to higher pressures compared to the triphylite Fe-M2(2+) end-member, in qualitative agreement with our experimental observations.
KW - Phosphates
KW - Triphylite
KW - Raman
KW - Infrared
KW - Optical absorption spectroscopy
KW - High pressure
KW - Spin transition
KW - DFT
Y1 - 2019
U6 - https://doi.org/10.1007/s00269-018-1001-y
SN - 0342-1791
SN - 1432-2021
VL - 46
IS - 3
SP - 245
EP - 258
PB - Springer
CY - New York
ER -
TY - JOUR
A1 - Grott, Matthias
A1 - Knollenberg, J.
A1 - Hamm, M.
A1 - Ogawa, K.
A1 - Jaumann, R.
A1 - Otto, Katharina Alexandra
A1 - Delbo, M.
A1 - Michel, P.
A1 - Biele, J.
A1 - Neumann, W.
A1 - Knapmeyer, M.
A1 - Kuehrt, E.
A1 - Senshu, H.
A1 - Okada, T.
A1 - Helbert, J.
A1 - Maturilli, A.
A1 - Müller, N.
A1 - Hagermann, A.
A1 - Sakatani, N.
A1 - Tanaka, S.
A1 - Arai, T.
A1 - Mottola, S.
A1 - Tachibana, S.
A1 - Pelivan, Ivanka
A1 - Drube, L.
A1 - Vincent, J-B
A1 - Yano, H.
A1 - Pilorget, C.
A1 - Matz, K. D.
A1 - Schmitz, N.
A1 - Koncz, A.
A1 - Schröder, S. E.
A1 - Trauthan, F.
A1 - Schlotterer, M.
A1 - Krause, C.
A1 - Ho, T-M
A1 - Moussi-Soffys, A.
T1 - Low thermal conductivity boulder with high porosity identified on C-type asteroid (162173) Ryugu
JF - Nature astronomy
N2 - C-type asteroids are among the most pristine objects in the Solar System, but little is known about their interior structure and surface properties. Telescopic thermal infrared observations have so far been interpreted in terms of a regolith-covered surface with low thermal conductivity and particle sizes in the centimetre range. This includes observations of C-type asteroid (162173) Ryugu1,2,3. However, on arrival of the Hayabusa2 spacecraft at Ryugu, a regolith cover of sand- to pebble-sized particles was found to be absent4,5 (R.J. et al., manuscript in preparation). Rather, the surface is largely covered by cobbles and boulders, seemingly incompatible with the remote-sensing infrared observations. Here we report on in situ thermal infrared observations of a boulder on the C-type asteroid Ryugu. We found that the boulder’s thermal inertia was much lower than anticipated based on laboratory measurements of meteorites, and that a surface covered by such low-conductivity boulders would be consistent with remote-sensing observations. Our results furthermore indicate high boulder porosities as well as a low tensile strength in the few hundred kilopascal range. The predicted low tensile strength confirms the suspected observational bias6 in our meteorite collections, as such asteroidal material would be too frail to survive atmospheric entry7.
Y1 - 2020
U6 - https://doi.org/10.1038/s41550-019-0832-x
SN - 2397-3366
VL - 3
IS - 11
SP - 971
EP - 976
PB - Nature Publishing Group
CY - London
ER -
TY - JOUR
A1 - Srama, Ralf
A1 - Ahrens, Thomas J.
A1 - Altobelli, Nicolas
A1 - Auer, S.
A1 - Bradley, J. G.
A1 - Burton, M.
A1 - Dikarev, V. V.
A1 - Economou, T.
A1 - Fechtig, Hugo
A1 - Görlich, M.
A1 - Grande, M.
A1 - Graps, Amara
A1 - Grün, Eberhard
A1 - Havnes, Ove
A1 - Helfert, Stefan
A1 - Horanyi, Mihaly
A1 - Igenbergs, E.
A1 - Jessberger, Elmar K.
A1 - Johnson, T. V.
A1 - Kempf, Sascha
A1 - Krivov, Alexander v.
A1 - Krüger, Harald
A1 - Mocker-Ahlreep, Anna
A1 - Moragas-Klostermeyer, Georg
A1 - Lamy, Philippe
A1 - Landgraf, Markus
A1 - Linkert, Dietmar
A1 - Linkert, G.
A1 - Lura, F.
A1 - McDonnell, J. A. M.
A1 - Moehlmann, Dirk
A1 - Morfill, Gregory E.
A1 - Muller, M.
A1 - Roy, M.
A1 - Schafer, G.
A1 - Schlotzhauer, G.
A1 - Schwehm, Gerhard H.
A1 - Spahn, Frank
A1 - Stübig, M.
A1 - Svestka, Jiri
A1 - Tschernjawski, V
T1 - The Cassini Cosmic Dust Analyzer
N2 - The Cassini-Huygens Cosmic Dust Analyzer (CDA) is intended to provide direct observations of dust grains with masses between 10(-19) and 10(-9) kg in interplanetary space and in the jovian and saturnian systems, to investigate their physical, chemical and dynamical properties as functions of the distances to the Sun, to Jupiter and to Saturn and its satellites and rings, to study their interaction with the saturnian rings, satellites and magnetosphere. Chemical composition of interplanetary meteoroids will be compared with asteroidal and cometary dust, as well as with Saturn dust, ejecta from rings and satellites. Ring and satellites phenomena which might be effects of meteoroid impacts will be compared with the interplanetary dust environment. Electrical charges of particulate matter in the magnetosphere and its consequences will be studied, e.g. the effects of the ambient plasma and the magnetic held on the trajectories of dust particles as well as fragmentation of particles due to electrostatic disruption. The investigation will be performed with an instrument that measures the mass, composition, electric charge, speed, and flight direction of individual dust particles. It is a highly reliable and versatile instrument with a mass sensitivity 106 times higher than that of the Pioneer 10 and I I dust detectors which measured dust in the saturnian system. The Cosmic Dust Analyzer has significant inheritance from former space instrumentation developed for the VEGA, Giotto, Galileo, and Ulysses missions. It will reliably measure impacts from as low as I impact per month up to 104 impacts per second. The instrument weighs 17 kg and consumes 12 W, the integrated time-of-flight mass spectrometer has a mass resolution of up to 50. The nominal data transmission rate is 524 bits/s and varies between 50 and 4192 bps
Y1 - 2004
SN - 0038-6308
ER -
TY - JOUR
A1 - Read, Betsy A.
A1 - Kegel, Jessica
A1 - Klute, Mary J.
A1 - Kuo, Alan
A1 - Lefebvre, Stephane C.
A1 - Maumus, Florian
A1 - Mayer, Christoph
A1 - Miller, John
A1 - Monier, Adam
A1 - Salamov, Asaf
A1 - Young, Jeremy
A1 - Aguilar, Maria
A1 - Claverie, Jean-Michel
A1 - Frickenhaus, Stephan
A1 - Gonzalez, Karina
A1 - Herman, Emily K.
A1 - Lin, Yao-Cheng
A1 - Napier, Johnathan
A1 - Ogata, Hiroyuki
A1 - Sarno, Analissa F.
A1 - Shmutz, Jeremy
A1 - Schroeder, Declan
A1 - de Vargas, Colomban
A1 - Verret, Frederic
A1 - von Dassow, Peter
A1 - Valentin, Klaus
A1 - Van de Peer, Yves
A1 - Wheeler, Glen
A1 - Dacks, Joel B.
A1 - Delwiche, Charles F.
A1 - Dyhrman, Sonya T.
A1 - Glöckner, Gernot
A1 - John, Uwe
A1 - Richards, Thomas
A1 - Worden, Alexandra Z.
A1 - Zhang, Xiaoyu
A1 - Grigoriev, Igor V.
A1 - Allen, Andrew E.
A1 - Bidle, Kay
A1 - Borodovsky, M.
A1 - Bowler, C.
A1 - Brownlee, Colin
A1 - Cock, J. Mark
A1 - Elias, Marek
A1 - Gladyshev, Vadim N.
A1 - Groth, Marco
A1 - Guda, Chittibabu
A1 - Hadaegh, Ahmad
A1 - Iglesias-Rodriguez, Maria Debora
A1 - Jenkins, J.
A1 - Jones, Bethan M.
A1 - Lawson, Tracy
A1 - Leese, Florian
A1 - Lindquist, Erika
A1 - Lobanov, Alexei
A1 - Lomsadze, Alexandre
A1 - Malik, Shehre-Banoo
A1 - Marsh, Mary E.
A1 - Mackinder, Luke
A1 - Mock, Thomas
A1 - Müller-Röber, Bernd
A1 - Pagarete, Antonio
A1 - Parker, Micaela
A1 - Probert, Ian
A1 - Quesneville, Hadi
A1 - Raines, Christine
A1 - Rensing, Stefan A.
A1 - Riano-Pachon, Diego Mauricio
A1 - Richier, Sophie
A1 - Rokitta, Sebastian
A1 - Shiraiwa, Yoshihiro
A1 - Soanes, Darren M.
A1 - van der Giezen, Mark
A1 - Wahlund, Thomas M.
A1 - Williams, Bryony
A1 - Wilson, Willie
A1 - Wolfe, Gordon
A1 - Wurch, Louie L.
T1 - Pan genome of the phytoplankton Emiliania underpins its global distribution
JF - Nature : the international weekly journal of science
N2 - Coccolithophores have influenced the global climate for over 200 million years(1). These marine phytoplankton can account for 20 per cent of total carbon fixation in some systems(2). They form blooms that can occupy hundreds of thousands of square kilometres and are distinguished by their elegantly sculpted calcium carbonate exoskeletons (coccoliths), rendering them visible from space(3). Although coccolithophores export carbon in the form of organic matter and calcite to the sea floor, they also release CO2 in the calcification process. Hence, they have a complex influence on the carbon cycle, driving either CO2 production or uptake, sequestration and export to the deep ocean(4). Here we report the first haptophyte reference genome, from the coccolithophore Emiliania huxleyi strain CCMP1516, and sequences from 13 additional isolates. Our analyses reveal a pan genome (core genes plus genes distributed variably between strains) probably supported by an atypical complement of repetitive sequence in the genome. Comparisons across strains demonstrate that E. huxleyi, which has long been considered a single species, harbours extensive genome variability reflected in different metabolic repertoires. Genome variability within this species complex seems to underpin its capacity both to thrive in habitats ranging from the equator to the subarctic and to form large-scale episodic blooms under a wide variety of environmental conditions.
Y1 - 2013
U6 - https://doi.org/10.1038/nature12221
SN - 0028-0836
SN - 1476-4687
VL - 499
IS - 7457
SP - 209
EP - 213
PB - Nature Publ. Group
CY - London
ER -
TY - JOUR
A1 - Christakoudi, Sofia
A1 - Pagoni, Panagiota
A1 - Ferrari, Pietro
A1 - Cross, Amanda J.
A1 - Tzoulaki, Ioanna
A1 - Muller, David C.
A1 - Weiderpass, Elisabete
A1 - Freisling, Heinz
A1 - Murphy, Neil
A1 - Dossus, Laure
A1 - Turzanski Fortner, Renee
A1 - Agudo, Antonio
A1 - Overvad, Kim
A1 - Perez-Cornago, Aurora
A1 - Key, Timothy J.
A1 - Brennan, Paul
A1 - Johansson, Mattias
A1 - Tjonneland, Anne
A1 - Halkjaer, Jytte
A1 - Boutron-Ruault, Marie-Christine
A1 - Artaud, Fanny
A1 - Severi, Gianluca
A1 - Kaaks, Rudolf
A1 - Schulze, Matthias Bernd
A1 - Bergmann, Manuela M.
A1 - Masala, Giovanna
A1 - Grioni, Sara
A1 - Simeon, Vittorio
A1 - Tumino, Rosario
A1 - Sacerdote, Carlotta
A1 - Skeie, Guri
A1 - Rylander, Charlotta
A1 - Borch, Kristin Benjaminsen
A1 - Quiros, J. Ramon
A1 - Rodriguez-Barranco, Miguel
A1 - Chirlaque, Maria-Dolores
A1 - Ardanaz, Eva
A1 - Amiano, Pilar
A1 - Drake, Isabel
A1 - Stocks, Tanja
A1 - Häggström, Christel
A1 - Harlid, Sophia
A1 - Ellingjord-Dale, Merete
A1 - Riboli, Elio
A1 - Tsilidis, Konstantinos K.
T1 - Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
JF - International journal of cancer
N2 - Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) category during middle adulthood with 42 cancers, using multivariable Cox proportional hazards models in the European Prospective Investigation into Cancer and Nutrition cohort. Of 241 323 participants (31% men), 20% lost and 32% gained weight (>0.4 to 5.0 kg/year) during 6.9 years (average). During 8.0 years of follow-up after the second weight assessment, 20 960 incident cancers were ascertained. Independent of baseline BMI, weight gain (per one kg/year increment) was positively associated with cancer of the corpus uteri (hazard ratio [HR] = 1.14; 95% confidence interval: 1.05-1.23). Compared to stable weight (+/- 0.4 kg/year), weight gain (>0.4 to 5.0 kg/year) was positively associated with cancers of the gallbladder and bile ducts (HR = 1.41; 1.01-1.96), postmenopausal breast (HR = 1.08; 1.00-1.16) and thyroid (HR = 1.40; 1.04-1.90). Compared to maintaining normal weight, maintaining overweight or obese BMI (World Health Organisation categories) was positively associated with most obesity-related cancers. Compared to maintaining the baseline BMI category, weight gain to a higher BMI category was positively associated with cancers of the postmenopausal breast (HR = 1.19; 1.06-1.33), ovary (HR = 1.40; 1.04-1.91), corpus uteri (HR = 1.42; 1.06-1.91), kidney (HR = 1.80; 1.20-2.68) and pancreas in men (HR = 1.81; 1.11-2.95). Losing weight to a lower BMI category, however, was inversely associated with cancers of the corpus uteri (HR = 0.40; 0.23-0.69) and colon (HR = 0.69; 0.52-0.92). Our findings support avoiding weight gain and encouraging weight loss in middle adulthood.
KW - BMI change
KW - cancer
KW - middle adulthood
KW - weight gain
KW - weight loss
Y1 - 2020
U6 - https://doi.org/10.1002/ijc.33339
SN - 0020-7136
SN - 1097-0215
VL - 148
IS - 7
SP - 1637
EP - 1651
PB - Wiley
CY - Hoboken
ER -
TY - GEN
A1 - Christakoudi, Sofia
A1 - Pagoni, Panagiota
A1 - Ferrari, Pietro
A1 - Cross, Amanda J.
A1 - Tzoulaki, Ioanna
A1 - Muller, David C.
A1 - Weiderpass, Elisabete
A1 - Freisling, Heinz
A1 - Murphy, Neil
A1 - Dossus, Laure
A1 - Turzanski Fortner, Renee
A1 - Agudo, Antonio
A1 - Overvad, Kim
A1 - Perez-Cornago, Aurora
A1 - Key, Timothy J.
A1 - Brennan, Paul
A1 - Johansson, Mattias
A1 - Tjonneland, Anne
A1 - Halkjaer, Jytte
A1 - Boutron-Ruault, Marie-Christine
A1 - Artaud, Fanny
A1 - Severi, Gianluca
A1 - Kaaks, Rudolf
A1 - Schulze, Matthias Bernd
A1 - Bergmann, Manuela M.
A1 - Masala, Giovanna
A1 - Grioni, Sara
A1 - Simeon, Vittorio
A1 - Tumino, Rosario
A1 - Sacerdote, Carlotta
A1 - Skeie, Guri
A1 - Rylander, Charlotta
A1 - Borch, Kristin Benjaminsen
A1 - Quiros, J. Ramon
A1 - Rodriguez-Barranco, Miguel
A1 - Chirlaque, Maria-Dolores
A1 - Ardanaz, Eva
A1 - Amiano, Pilar
A1 - Drake, Isabel
A1 - Stocks, Tanja
A1 - Haggstrom, Christel
A1 - Harlid, Sophia
A1 - Ellingjord-Dale, Merete
A1 - Riboli, Elio
A1 - Tsilidis, Konstantinos K.
T1 - Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
T2 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2 - Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) category during middle adulthood with 42 cancers, using multivariable Cox proportional hazards models in the European Prospective Investigation into Cancer and Nutrition cohort. Of 241 323 participants (31% men), 20% lost and 32% gained weight (>0.4 to 5.0 kg/year) during 6.9 years (average). During 8.0 years of follow-up after the second weight assessment, 20 960 incident cancers were ascertained. Independent of baseline BMI, weight gain (per one kg/year increment) was positively associated with cancer of the corpus uteri (hazard ratio [HR] = 1.14; 95% confidence interval: 1.05-1.23). Compared to stable weight (+/- 0.4 kg/year), weight gain (>0.4 to 5.0 kg/year) was positively associated with cancers of the gallbladder and bile ducts (HR = 1.41; 1.01-1.96), postmenopausal breast (HR = 1.08; 1.00-1.16) and thyroid (HR = 1.40; 1.04-1.90). Compared to maintaining normal weight, maintaining overweight or obese BMI (World Health Organisation categories) was positively associated with most obesity-related cancers. Compared to maintaining the baseline BMI category, weight gain to a higher BMI category was positively associated with cancers of the postmenopausal breast (HR = 1.19; 1.06-1.33), ovary (HR = 1.40; 1.04-1.91), corpus uteri (HR = 1.42; 1.06-1.91), kidney (HR = 1.80; 1.20-2.68) and pancreas in men (HR = 1.81; 1.11-2.95). Losing weight to a lower BMI category, however, was inversely associated with cancers of the corpus uteri (HR = 0.40; 0.23-0.69) and colon (HR = 0.69; 0.52-0.92). Our findings support avoiding weight gain and encouraging weight loss in middle adulthood.
T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1373
KW - BMI change
KW - cancer
KW - middle adulthood
KW - weight gain
KW - weight loss
Y1 - 2020
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-573609
SN - 1866-8372
IS - 7
ER -
TY - JOUR
A1 - Grott, Matthias
A1 - Knollenberg, J.
A1 - Hamm, M.
A1 - Ogawa, K.
A1 - Jaumann, R.
A1 - Otto, Katharina Alexandra
A1 - Delbo, M.
A1 - Michel, Patrick
A1 - Biele, J.
A1 - Neumann, Wladimir
A1 - Knapmeyer, Martin
A1 - Kührt, E.
A1 - Senshu, H.
A1 - Okada, T.
A1 - Helbert, Jorn
A1 - Maturilli, A.
A1 - Müller, N.
A1 - Hagermann, A.
A1 - Sakatani, Naoya
A1 - Tanaka, S.
A1 - Arai, T.
A1 - Mottola, Stefano
A1 - Tachibana, Shogo
A1 - Pelivan, Ivanka
A1 - Drube, Line
A1 - Vincent, J-B
A1 - Yano, Hajime
A1 - Pilorget, C.
A1 - Matz, K. D.
A1 - Schmitz, N.
A1 - Koncz, A.
A1 - Schröder, Stefan E.
A1 - Trauthan, F.
A1 - Schlotterer, Markus
A1 - Krause, C.
A1 - Ho, T-M
A1 - Moussi-Soffys, A.
T1 - Low thermal conductivity boulder with high porosity identified on C-type asteroid (162173) Ryugu
JF - Nature astronomy
N2 - C-type asteroids are among the most pristine objects in the Solar System, but little is known about their interior structure and surface properties. Telescopic thermal infrared observations have so far been interpreted in terms of a regolith-covered surface with low thermal conductivity and particle sizes in the centimetre range. This includes observations of C-type asteroid (162173) Ryugu1,2,3. However, on arrival of the Hayabusa2 spacecraft at Ryugu, a regolith cover of sand- to pebble-sized particles was found to be absent4,5 (R.J. et al., manuscript in preparation). Rather, the surface is largely covered by cobbles and boulders, seemingly incompatible with the remote-sensing infrared observations. Here we report on in situ thermal infrared observations of a boulder on the C-type asteroid Ryugu. We found that the boulder’s thermal inertia was much lower than anticipated based on laboratory measurements of meteorites, and that a surface covered by such low-conductivity boulders would be consistent with remote-sensing observations. Our results furthermore indicate high boulder porosities as well as a low tensile strength in the few hundred kilopascal range. The predicted low tensile strength confirms the suspected observational bias6 in our meteorite collections, as such asteroidal material would be too frail to survive atmospheric entry7
Y1 - 2019
U6 - https://doi.org/10.1038/s41550-019-0832-x
SN - 2397-3366
VL - 3
IS - 11
SP - 971
EP - 976
PB - Nature Publishing Group
CY - London
ER -
TY - JOUR
A1 - Kohlmorgen, J.
A1 - Müller, Klaus-Robert
A1 - Rittweger, J.
A1 - Pawelzik, K.
T1 - Identification of nonstationary dynamics in physiological recordings
Y1 - 2000
ER -
TY - JOUR
A1 - Mika, Sebastian
A1 - Rätsch, Gunnar
A1 - Weston, J.
A1 - Schölkopf, B.
A1 - Smola, Alexander J.
A1 - Müller, Klaus-Robert
T1 - Invariant feature extraction and classification in kernel spaces
Y1 - 2000
ER -
TY - JOUR
A1 - Barbirz, Stefanie
A1 - Müller, Jürgen J.
A1 - Uetrecht, Charlotte
A1 - Clark, Alvin J.
A1 - Heinemann, Udo
A1 - Seckler, Robert
T1 - Crystal structure of Escherichia coli phage HK620 tailspike : podoviral tailspike endoglycosidase modules are evolutionarily related
N2 - Bacteriophage HK620 infects Escherichia coli H and is closely related to Shigella phage Sf6 and Salmonella phage P22. All three Podoviridae recognize and cleave their respective host cell receptor polysaccharide by homotrimeric tailspike proteins. The three proteins exhibit high sequence identity in the 110 residues of their N-terminal particle- binding domains, but no apparent sequence similarity in their major, receptor-binding parts. We have biochemically characterized the receptor-binding part of HK620 tailspike and determined its crystal structure to 1.38 Å resolution. Its major domain is a right-handed parallel ;-helix, as in Sf6 and P22 tailspikes. HK620 tailspike has endo-N- acetylglucosaminidase activity and produces hexasaccharides of an O18A1-type O-antigen. As indicated by the structure of a hexasaccharide complex determined at 1.6 Å resolution, the endoglycosidase-active sites are located intramolecularly, as in P22, and not between subunits, as in Sf6 tailspike. In contrast, the extreme C-terminal domain of HK620 tailspike forms a ;-sandwich, as in Sf6 and unlike P22 tailspike. Despite the different folds, structure-based sequence alignments of the C-termini reveal motifs conserved between the three proteins. We propose that the tailspike genes of P22, Sf6 and HK620 have a common precursor and are not mosaics of unrelated gene fragments.
Y1 - 2008
UR - http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2958.2008.06311.x/pdf
SN - 0950-382X
ER -
TY - JOUR
A1 - Rohrmann, Johannes
A1 - Tohge, Takayuki
A1 - Alba, Rob
A1 - Osorio, Sonia
A1 - Caldana, Camila
A1 - McQuinn, Ryan
A1 - Arvidsson, Samuel Janne
A1 - van der Merwe, Margaretha J.
A1 - Riano-Pachon, Diego Mauricio
A1 - Müller-Röber, Bernd
A1 - Fei, Zhangjun
A1 - Nesi, Adriano Nunes
A1 - Giovannoni, James J.
A1 - Fernie, Alisdair R.
T1 - Combined transcription factor profiling, microarray analysis and metabolite profiling reveals the transcriptional control of metabolic shifts occurring during tomato fruit development
JF - The plant journal
N2 - Maturation of fleshy fruits such as tomato (Solanum lycopersicum) is subject to tight genetic control. Here we describe the development of a quantitative real-time PCR platform that allows accurate quantification of the expression level of approximately 1000 tomato transcription factors. In addition to utilizing this novel approach, we performed cDNA microarray analysis and metabolite profiling of primary and secondary metabolites using GC-MS and LC-MS, respectively. We applied these platforms to pericarp material harvested throughout fruit development, studying both wild-type Solanum lycopersicum cv. Ailsa Craig and the hp1 mutant. This mutant is functionally deficient in the tomato homologue of the negative regulator of the light signal transduction gene DDB1 from Arabidopsis, and is furthermore characterized by dramatically increased pigment and phenolic contents. We choose this particular mutant as it had previously been shown to have dramatic alterations in the content of several important fruit metabolites but relatively little impact on other ripening phenotypes. The combined dataset was mined in order to identify metabolites that were under the control of these transcription factors, and, where possible, the respective transcriptional regulation underlying this control. The results are discussed in terms of both programmed fruit ripening and development and the transcriptional and metabolic shifts that occur in parallel during these processes.
KW - transcription factor
KW - Solanum lycopersicum
KW - quantitative RT-PCR
KW - microarray
KW - metabolomics
KW - fleshy fruit ripening
Y1 - 2011
U6 - https://doi.org/10.1111/j.1365-313X.2011.04750.x
SN - 0960-7412
VL - 68
IS - 6
SP - 999
EP - 1013
PB - Wiley-Blackwell
CY - Malden
ER -
TY - JOUR
A1 - Diekmann, Martin
A1 - Andres, Christian
A1 - Becker, Thomas
A1 - Bennie, Jonathan
A1 - Blueml, Volker
A1 - Bullock, James M.
A1 - Culmsee, Heike
A1 - Fanigliulo, Miriam
A1 - Hahn, Annett
A1 - Heinken, Thilo
A1 - Leuschner, Christoph
A1 - Luka, Stefanie
A1 - Meissner, Justus
A1 - Müller, Josef
A1 - Newton, Adrian
A1 - Peppler-Lisbach, Cord
A1 - Rosenthal, Gert
A1 - van den Berg, Leon J. L.
A1 - Vergeer, Philippine
A1 - Wesche, Karsten
T1 - Patterns of long-term vegetation change vary between different types of semi-natural grasslands in Western and Central Europe
JF - Journal of vegetation science
N2 - Questions Has plant species richness in semi-natural grasslands changed over recent decades? Do the temporal trends of habitat specialists differ from those of habitat generalists? Has there been a homogenization of the grassland vegetation? Location Different regions in Germany and the UK. Methods We conducted a formal meta-analysis of re-survey vegetation studies of semi-natural grasslands. In total, 23 data sets were compiled, spanning up to 75 years between the surveys, including 13 data sets from wet grasslands, six from dry grasslands and four from other grassland types. Edaphic conditions were assessed using mean Ellenberg indicator values for soil moisture, nitrogen and pH. Changes in species richness and environmental variables were evaluated using response ratios. Results In most wet grasslands, total species richness declined over time, while habitat specialists almost completely vanished. The number of species losses increased with increasing time between the surveys and were associated with a strong decrease in soil moisture and higher soil nutrient contents. Wet grasslands in nature reserves showed no such changes or even opposite trends. In dry grasslands and other grassland types, total species richness did not consistently change, but the number or proportions of habitat specialists declined. There were also considerable changes in species composition, especially in wet grasslands that often have been converted into intensively managed, highly productive meadows or pastures. We did not find a general homogenization of the vegetation in any of the grassland types. Conclusions The results document the widespread deterioration of semi-natural grasslands, especially of those types that can easily be transformed to high production grasslands. The main causes for the loss of grassland specialists are changed management in combination with increased fertilization and nitrogen deposition. Dry grasslands are most resistant to change, but also show a long-term trend towards an increase in more mesotrophic species.
KW - dry grasslands
KW - fragmentation
KW - homogenization
KW - management
KW - meta-analysis
KW - nitrogen deposition
KW - quasi-permanent plot
KW - re-survey
KW - species richness
KW - wet grasslands
Y1 - 2019
U6 - https://doi.org/10.1111/jvs.12727
SN - 1100-9233
SN - 1654-1103
VL - 30
IS - 2
SP - 187
EP - 202
PB - Wiley
CY - Hoboken
ER -
TY - THES
A1 - Müller, Melanie J. I.
T1 - Bidirectional transport by molecular motors
T1 - Bidirektionaler Transport durch molekulare Motoren
N2 - In biological cells, the long-range intracellular traffic is powered by molecular motors which transport various cargos along microtubule filaments. The microtubules possess an intrinsic direction, having a 'plus' and a 'minus' end. Some molecular motors such as cytoplasmic dynein walk to the minus end, while others such as conventional kinesin walk to the plus end. Cells typically have an isopolar microtubule network. This is most pronounced in neuronal axons or fungal hyphae. In these long and thin tubular protrusions, the microtubules are arranged parallel to the tube axis with the minus ends pointing to the cell body and the plus ends pointing to the tip. In such a tubular compartment, transport by only one motor type leads to 'motor traffic jams'. Kinesin-driven cargos accumulate at the tip, while dynein-driven cargos accumulate near the cell body. We identify the relevant length scales and characterize the jamming behaviour in these tube geometries by using both Monte Carlo simulations and analytical calculations. A possible solution to this jamming problem is to transport cargos with a team of plus and a team of minus motors simultaneously, so that they can travel bidirectionally, as observed in cells. The presumably simplest mechanism for such bidirectional transport is provided by a 'tug-of-war' between the two motor teams which is governed by mechanical motor interactions only. We develop a stochastic tug-of-war model and study it with numerical and analytical calculations. We find a surprisingly complex cooperative motility behaviour. We compare our results to the available experimental data, which we reproduce qualitatively and quantitatively.
N2 - In biologischen Zellen transportieren molekulare Motoren verschiedenste Frachtteilchen entlang von Mikrotubuli-Filamenten. Die Mikrotubuli-Filamente besitzen eine intrinsische Richtung: sie haben ein "Plus-" und ein "Minus-"Ende. Einige molekulare Motoren wie Dynein laufen zum Minus-Ende, während andere wie Kinesin zum Plus-Ende laufen. Zellen haben typischerweise ein isopolares Mikrotubuli-Netzwerk. Dies ist besonders ausgeprägt in neuronalen Axonen oder Pilz-Hyphen. In diesen langen röhrenförmigen Ausstülpungen liegen die Mikrotubuli parallel zur Achse mit dem Minus-Ende zum Zellkörper und dem Plus-Ende zur Zellspitze gerichtet. In einer solchen Röhre führt Transport durch nur einen Motor-Typ zu "Motor-Staus". Kinesin-getriebene Frachten akkumulieren an der Spitze, während Dynein-getriebene Frachten am Zellkörper akkumulieren. Wir identifizieren die relevanten Längenskalen und charakterisieren das Stauverhalten in diesen Röhrengeometrien mit Hilfe von Monte-Carlo-Simulationen und analytischen Rechnungen. Eine mögliche Lösung für das Stauproblem ist der Transport mit einem Team von Plus- und einem Team von Minus-Motoren gleichzeitig, so dass die Fracht sich in beide Richtungen bewegen kann. Dies wird in Zellen tatsächlich beobachtet. Der einfachste Mechanismus für solchen bidirektionalen Transport ist ein "Tauziehen" zwischen den beiden Motor-Teams, das nur mit mechanischer Interaktion funktioniert. Wir entwickeln ein stochastisches Tauzieh-Modell, das wir mit numerischen und analytischen Rechnungen untersuchen. Es ergibt sich ein erstaunlich komplexes Motilitätsverhalten. Wir vergleichen unsere Resultate mit den vorhandenen experimentellen Daten, die wir qualitativ und quantitativ reproduzieren.
KW - molekulare Motoren
KW - bidirektionaler intrazellulärer Transport
KW - Tauziehen
KW - stochastische Prozesse
KW - kooperative Phänomene
KW - molecular motors
KW - bidirectional intracellular transport
KW - tug-of-war
KW - stochastic processes
KW - cooperative phenomena
Y1 - 2008
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-18715
ER -
TY - JOUR
A1 - Askin, Elif
A1 - Emmerich-Fritsche, Angelika
A1 - Goppel, Anna
A1 - Hemmerling, Mario
A1 - Kapaun, Nina
A1 - Lohmann, Georg
A1 - Müller, Sebastian
A1 - Niederberger, Andreas
A1 - Pabel, Katharina
A1 - Putzer, Max
A1 - Roth-Isigkeit, David
A1 - Seidler, Christoph
A1 - Tiedemann, Paul
A1 - Vasel, J. Justus
A1 - Weiß, Norman
T1 - MenschenRechtsMagazin : Informationen | Meinungen | Analysen
N2 - Aus dem Inhalt: - Themenschwerpunkt: Menschenrechte und Staatsbürgerschaft - Gibt es Menschenrechte ohne Bürgerschaft? - Menschenwürde und Staatsbürgerschaft - Die General Comments des Menschenrechtsausschusses der Vereinten Nationen – ein Beitrag zur Rechtsentwicklung im Völkerrecht - Politische Selbstbestimmung als Menschenrecht und im Völkerrecht - Libyen und der von außen unterstützte Systemwechsel
T3 - MenschenRechtsMagazin : MRM ; Informationen, Meinungen, Analysen - 17.2012/2
Y1 - 2012
U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-62122
SN - 1434-2820
VL - 17
IS - 2
PB - Universitätsverlag Potsdam
CY - Potsdam
ER -