TY  - JOUR
A1  - Cywinski, Piotr J.
A1  - Idzik, Krzysztof R.
A1  - Cranfield, Charles G.
A1  - Beckert, Rainer
A1  - Mohr, Gerhard J.
T1  - Synthesis and sensing properties of a new carbazole fluorosensor for detection of abacavir
N2  - An abacavir-targeted fluorosensor based on the carbazole moiety has been synthesised and characterised. Recognition of abacavir is by base pairing between a uracil moiety present in the fluorosensor and the guanine moiety of abacavir. The fluorosensor exhibits five-fold quenching in the presence of 50M abacavir. Its sensitivity to abacavir is superior to that of other reverse transcriptase inhibitors: zidovudine, lamivudine and didanosine. Due to its high sensitivity, this fluorosensor has the potential to be used in multi-analyte array-based detection platforms as well as in microfluidics systems.
Y1  - 2010
UR  - http://www.informaworld.com/openurl?genre=journal&issn=1061-0278
U6  - https://doi.org/10.1080/10610278.2010.506541
SN  - 1061-0278
ER  - 
TY  - JOUR
A1  - Schaffer, Mario
A1  - Idzik, Krzysztof R.
A1  - Wilke, Max
A1  - Licha, Tobias
T1  - Amides as thermo-sensitive tracers for investigating the thermal state of geothermal reservoirs
JF  - Geothermics : an international journal of geothermal research and its applications
N2  - The application of thermo-sensitive tracers is a promising technique for evaluating the thermal state of geothermal reservoirs. To extend the compound spectrum for hydrolyzable compounds to reservoir temperatures between 100 and 200 degrees C carboxamides were studied. The kinetic parameters of 17 self-synthesized amides were determined in hydrothermal batch and autoclave experiments. The influence of the molecular structure and the role of pH/pOH on hydrolysis kinetics were studied. Additionally, the thermal stabilities of the hydrolysis products were evaluated. The results demonstrate the high potential of tracers based on amide hydrolysis for use in medium enthalpy reservoirs. (C) 2016 Elsevier Ltd. All rights reserved.
KW  - Thermo-sensitive tracers
KW  - Amides
KW  - Hydrolysis
KW  - Kinetics
KW  - Reservoir temperature
KW  - Molecular design
Y1  - 2016
U6  - https://doi.org/10.1016/j.geothermics.2016.05.004
SN  - 0375-6505
SN  - 1879-3576
VL  - 64
SP  - 180
EP  - 186
PB  - Elsevier
CY  - Oxford
ER  -