TY - JOUR A1 - Li, Jian A1 - Lu, Yong-Ping A1 - Tsuprykov, Oleg A1 - Hasan, Ahmed Abdallah Abdalrahman Mohamed A1 - Reichetzeder, Christoph A1 - Tian, Mei A1 - Zhang, Xiao Li A1 - Zhang, Qin A1 - Sun, Guo-Ying A1 - Guo, Jingli A1 - Gaballa, Mohamed Mahmoud Salem Ahmed A1 - Peng, Xiao-Ning A1 - Lin, Ge A1 - Hocher, Berthold T1 - Folate treatment of pregnant rat dams abolishes metabolic effects in female offspring induced by a paternal pre-conception unhealthy diet JF - Diabetologia : journal of the European Association for the Study of Diabetes (EASD) N2 - Aims/hypothesis Paternal high-fat diet prior to mating programmes impaired glucose tolerance in female offspring. We examined whether the metabolic consequences in offspring could be abolished by folate treatment of either the male rats before mating or the corresponding female rats during pregnancy. Methods Male F0 rats were fed either control diet or high-fat, high-sucrose and high-salt diet (HFSSD), with or without folate, before mating. Male rats were mated with control-diet-fed dams. After mating, the F0 dams were fed control diet with or without folate during pregnancy. KW - Glucose tolerance KW - High-fat-sucrose-salt diet KW - Maternal folate treatment KW - Paternal programming Y1 - 2018 U6 - https://doi.org/10.1007/s00125-018-4635-x SN - 0012-186X SN - 1432-0428 VL - 61 IS - 8 SP - 1862 EP - 1876 PB - Springer CY - New York ER - TY - JOUR A1 - Li, Yuanqing A1 - Chen, Li A1 - Nofal, Issam A1 - Chen, Mo A1 - Wang, Haibin A1 - Liu, Rui A1 - Chen, Qingyu A1 - Krstić, Miloš A1 - Shi, Shuting A1 - Guo, Gang A1 - Baeg, Sang H. A1 - Wen, Shi-Jie A1 - Wong, Richard T1 - Modeling and analysis of single-event transient sensitivity of a 65 nm clock tree JF - Microelectronics reliability N2 - The soft error rate (SER) due to heavy-ion irradiation of a clock tree is investigated in this paper. A method for clock tree SER prediction is developed, which employs a dedicated soft error analysis tool to characterize the single-event transient (SET) sensitivities of clock inverters and other commercial tools to calculate the SER through fault-injection simulations. A test circuit including a flip-flop chain and clock tree in a 65 nm CMOS technology is developed through the automatic ASIC design flow. This circuit is analyzed with the developed method to calculate its clock tree SER. In addition, this circuit is implemented in a 65 nm test chip and irradiated by heavy ions to measure its SER resulting from the SETs in the clock tree. The experimental and calculation results of this case study present good correlation, which verifies the effectiveness of the developed method. KW - Clock tree KW - Modeling KW - Single-event transient (SET) Y1 - 2018 U6 - https://doi.org/10.1016/j.microrel.2018.05.016 SN - 0026-2714 VL - 87 SP - 24 EP - 32 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Clavier, Pierre J. A1 - Guo, Li A1 - Paycha, Sylvie A1 - Zhang, Bin T1 - An algebraic formulation of the locality principle in renormalisation JF - European Journal of Mathematics N2 - We study the mathematical structure underlying the concept of locality which lies at the heart of classical and quantum field theory, and develop a machinery used to preserve locality during the renormalisation procedure. Viewing renormalisation in the framework of Connes and Kreimer as the algebraic Birkhoff factorisation of characters on a Hopf algebra with values in a Rota-Baxter algebra, we build locality variants of these algebraic structures, leading to a locality variant of the algebraic Birkhoff factorisation. This provides an algebraic formulation of the conservation of locality while renormalising. As an application in the context of the Euler-Maclaurin formula on lattice cones, we renormalise the exponential generating function which sums over the lattice points in a lattice cone. As a consequence, for a suitable multivariate regularisation, renormalisation from the algebraic Birkhoff factorisation amounts to composition by a projection onto holomorphic multivariate germs. KW - Locality KW - Renormalisation KW - Algebraic Birkhoff factorisation KW - Partial algebra KW - Hopf algebra KW - Rota-Baxter algebra KW - Multivariate meromorphic functions KW - Lattice cones Y1 - 2019 U6 - https://doi.org/10.1007/s40879-018-0255-8 SN - 2199-675X SN - 2199-6768 VL - 5 IS - 2 SP - 356 EP - 394 PB - Springer CY - Cham ER - TY - CHAP A1 - Clavier, Pierre J. A1 - Guo, Li A1 - Paycha, Sylvie A1 - Zhang, Bin T1 - Renormalisation and locality BT - branched zeta values T2 - Algebraic Combinatorics, Resurgence, Moulds and Applications (CARMA) Volume 2 Y1 - 2020 SN - 978-3-03719-205-4 print SN - 978-3-03719-705-9 online U6 - https://doi.org/10.4171/205 SP - 85 EP - 132 PB - European Mathematical Society Publishing House CY - Zürich ER - TY - JOUR A1 - Guo, Li A1 - Paycha, Sylvie A1 - Zhang, Bin T1 - Algebraic Birkhoff factorization and the Euler–Maclaurin formula on cones JF - Duke mathematical journal N2 - We equip the space of lattice cones with a coproduct which makes it a cograded, coaugmented, connnected coalgebra. The exponential generating sum and exponential generating integral on lattice cones can be viewed as linear maps on this space with values in the space of meromorphic germs with linear poles at zero. We investigate the subdivision properties-reminiscent of the inclusion-exclusion principle for the cardinal on finite sets-of such linear maps and show that these properties are compatible with the convolution quotient of maps on the coalgebra. Implementing the algebraic Birkhoff factorization procedure on the linear maps under consideration, we factorize the exponential generating sum as a convolution quotient of two maps, with each of the maps in the factorization satisfying a subdivision property. A direct computation shows that the polar decomposition of the exponential generating sum on a smooth lattice cone yields an Euler-Maclaurin formula. The compatibility with subdivisions of the convolution quotient arising in the algebraic Birkhoff factorization then yields the Euler-Maclaurin formula for any lattice cone. This provides a simple formula for the interpolating factor by means of a projection formula. Y1 - 2017 U6 - https://doi.org/10.1215/00127094-3715303 SN - 0012-7094 SN - 1547-7398 VL - 166 IS - 3 SP - 537 EP - 571 PB - Duke Univ. Press CY - Durham ER - TY - JOUR A1 - Zhang, Haocheng A1 - Chen, Xuhui A1 - Böttcher, Markus A1 - Guo, Fan A1 - Li, Hui T1 - Polarization swings reveal magnetic energy dissipation in blazars JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - The polarization signatures of blazar emissions are known to be highly variable. In addition to small fluctuations of the polarization angle around a mean value, large (greater than or similar to 180 degrees) polarization angle swings are sometimes observed. We suggest that such phenomena can be interpreted as arising from light travel time effects within an underlying axisymmetric emission region. We present the first simultaneous fitting of the multi-wavelength spectrum, variability, and time-dependent polarization features of a correlated optical and gamma-ray flaring event of the prominent blazar 3C279, which was accompanied by a drastic change in its polarization signatures. This unprecedented combination of spectral, variability, and polarization information in a coherent physical model allows us to place stringent constraints on the particle acceleration and magnetic field topology in the relativistic jet of a blazar, strongly favoring a scenario in which magnetic energy dissipation is the primary driver of the flare event. KW - galaxies: active KW - galaxies: jets KW - gamma-rays: galaxies KW - radiation mechanisms: nonthermal KW - relativistic processes Y1 - 2015 U6 - https://doi.org/10.1088/0004-637X/804/1/58 SN - 0004-637X SN - 1538-4357 VL - 804 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Guo, Li A1 - Paycha, Sylvie A1 - Zhang, Bin T1 - Conical zeta values and their double subdivision relations JF - Advances in mathematics N2 - We introduce the concept of a conical zeta value as a geometric generalization of a multiple zeta value in the context of convex cones. The quasi-shuffle and shuffle relations of multiple zeta values are generalized to open cone subdivision and closed cone subdivision relations respectively for conical zeta values. In order to achieve the closed cone subdivision relation, we also interpret linear relations among fractions as subdivisions of decorated closed cones. As a generalization of the double shuffle relation of multiple zeta values, we give the double subdivision relation of conical zeta values and formulate the extended double subdivision relation conjecture for conical zeta values. KW - Convex cones KW - Conical zeta values KW - Smooth cones KW - Decorated cones KW - Subdivisions KW - Multiple zeta values KW - Shuffles KW - Quasi-shuffles KW - Fractions with linear poles KW - Shintani zeta values Y1 - 2014 U6 - https://doi.org/10.1016/j.aim.2013.10.022 SN - 0001-8708 SN - 1090-2082 VL - 252 SP - 343 EP - 381 PB - Elsevier CY - San Diego ER - TY - JOUR A1 - Huang, Wentao A1 - Dupont-Nivet, Guillaume A1 - Lippert, Peter C. A1 - van Hinsbergen, Douwe J. J. A1 - Dekkers, Mark J. A1 - Waldrip, Ross A1 - Ganerod, Morgan A1 - Li, Xiaochun A1 - Guo, Zhaojie A1 - Kapp, Paul T1 - What was the Paleogene latitude of the Lhasa terrane? A reassessment of the geochronology and paleomagnetism of Linzizong volcanic rocks (Linzhou basin, Tibet) JF - Tectonics N2 - The Paleogene latitude of the Lhasa terrane (southern Tibet) can constrain the age of the onset of the India-Asia collision. Estimates for this latitude, however, vary from 5 degrees N to 30 degrees N, and thus, here, we reassess the geochronology and paleomagnetism of Paleogene volcanic rocks from the Linzizong Group in the Linzhou basin. The lower and upper parts of the section previously yielded particularly conflicting ages and paleolatitudes. We report consistent Ar-40/Ar-39 and U-Pb zircon dates of similar to 52Ma for the upper Linzizong, and Ar-40/Ar-39 dates (similar to 51Ma) from the lower Linzizong are significantly younger than U-Pb zircon dates (64-63Ma), suggesting that the lower Linzizong was thermally and/or chemically reset. Paleomagnetic results from 24 sites in lower Linzizong confirm a low apparent paleolatitude of similar to 5 degrees N, compared to the upper part (similar to 20 degrees N) and to underlying Cretaceous strata (similar to 20 degrees N). Detailed rock magnetic analyses, end-member modeling of magnetic components, and petrography from the lower and upper Linzizong indicate widespread secondary hematite in the lower Linzizong, whereas hematite is rare in upper Linzizong. Volcanic rocks of the lower Linzizong have been hydrothermally chemically remagnetized, whereas the upper Linzizong retains a primary remanence. We suggest that remagnetization was induced by acquisition of chemical and thermoviscous remanent magnetizations such that the shallow inclinations are an artifact of a tilt correction applied to a secondary remanence in lower Linzizong. We estimate that the Paleogene latitude of Lhasa terrane was 204 degrees N, consistent with previous results suggesting that India-Asia collision likely took place by similar to 52Ma at similar to 20 degrees N. KW - remagnetization KW - rock magnetism KW - geochronology KW - India-Asia collision Y1 - 2015 U6 - https://doi.org/10.1002/2014TC003787 SN - 0278-7407 SN - 1944-9194 VL - 34 IS - 3 SP - 594 EP - 622 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Huang, Wentao A1 - van Hinsbergen, Douwe J. J. A1 - Dekkers, Mark J. A1 - Garzanti, Eduardo A1 - Dupont-Nivet, Guillaume A1 - Lippert, Peter C. A1 - Li, Xiaochun A1 - Maffione, Marco A1 - Langereis, Cor G. A1 - Hu, Xiumian A1 - Guo, Zhaojie A1 - Kapp, Paul T1 - Paleolatitudes of the Tibetan Himalaya from primary and secondary magnetizations of Jurassic to Lower Cretaceous sedimentary rocks JF - Geochemistry, geophysics, geosystems N2 - The Tibetan Himalaya represents the northernmost continental unit of the Indian plate that collided with Asia in the Cenozoic. Paleomagnetic studies on the Tibetan Himalaya can help constrain the dimension and paleogeography of "Greater India,' the Indian plate lithosphere that subducted and underthrusted below Asia after initial collision. Here we present a paleomagnetic investigation of a Jurassic (limestones) and Lower Cretaceous (volcaniclastic sandstones) section of the Tibetan Himalaya. The limestones yielded positive fold test, showing a prefolding origin of the isolated remanent magnetizations. Detailed paleomagnetic analyses, rock magnetic tests, end-member modeling of acquisition curves of isothermal remanent magnetization, and petrographic investigation reveal that the magnetic carrier of the Jurassic limestones is authigenic magnetite, whereas the dominant magnetic carrier of the Lower Cretaceous volcaniclastic sandstones is detrital magnetite. Our observations lead us to conclude that the Jurassic limestones record a prefolding remagnetization, whereas the Lower Cretaceous volcaniclastic sandstones retain a primary remanence. The volcaniclastic sandstones yield an Early Cretaceous paleolatitude of 55.5 degrees S [52.5 degrees S, 58.6 degrees S] for the Tibetan Himalaya, suggesting it was part of the Indian continent at that time. The size of "Greater India' during Jurassic time cannot be estimated from these limestones. Instead, a paleolatitude of the Tibetan Himalaya of 23.8 degrees S [21.8 degrees S, 26.1 degrees S] during the remagnetization process is suggested. It is likely that the remagnetization, caused by the oxidation of early diagenetic pyrite to magnetite, was induced during 103-83 or 77-67 Ma. The inferred paleolatitudes at these two time intervals imply very different tectonic consequences for the Tibetan Himalaya. Y1 - 2015 U6 - https://doi.org/10.1002/2014GC005624 SN - 1525-2027 VL - 16 IS - 1 SP - 77 EP - 100 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Huang, Wentao A1 - Dupont-Nivet, Guillaume A1 - Lippert, Peter C. A1 - van Hinsbergen, Douwe J. J. A1 - Dekkers, Mark J. A1 - Guo, Zhaojie A1 - Waldrip, Ross A1 - Li, Xiaochun A1 - Zhang, Xiaoran A1 - Liu, Dongdong A1 - Kapp, Paul T1 - Can a primary remanence be retrieved from partially remagnetized Eocence volcanic rocks in the Nanmulin Basin (southern Tibet) to date the India-Asia collision? JF - Journal of geophysical research : Solid earth N2 - Paleomagnetic dating of the India-Asia collision hinges on determining the Paleogene latitude of the Lhasa terrane (southern Tibet). Reported latitudes range from 5 degrees N to 30 degrees N, however, leading to contrasting paleogeographic interpretations. Here we report new data from the Eocene Linzizong volcanic rocks in the Nanmulin Basin, which previously yielded data suggesting a low paleolatitude (similar to 10 degrees N). New zircon U-Pb dates indicate an age of similar to 52Ma. Negative fold tests, however, demonstrate that the isolated characteristic remanent magnetizations, with notably varying inclinations, are not primary. Rock magnetic analyses, end-member modeling of isothermal remanent magnetization acquisition curves, and petrographic observations are consistent with variable degrees of posttilting remagnetization due to low-temperature alteration of primary magmatic titanomagnetite and the formation of secondary pigmentary hematite that unblock simultaneously. Previously reported paleomagnetic data from the Nanmulin Basin implying low paleolatitude should thus not be used to estimate the time and latitude of the India-Asia collision. We show that the paleomagnetic inclinations vary linearly with the contribution of secondary hematite to saturation isothermal remanent magnetization. We tentatively propose a new method to recover a primary remanence with inclination of 38.1 degrees (35.7 degrees, 40.5 degrees) (95% significance) and a secondary remanence with inclination of 42.9 degrees (41.5 degrees,44.4 degrees) (95% significance). The paleolatitude defined by the modeled primary remanence21 degrees N (19.8 degrees N, 23.1 degrees N)is consistent with the regional compilation of published results from pristine volcanic rocks and sedimentary rocks of the upper Linzizong Group corrected for inclination shallowing. The start of the Tibetan Himalaya-Asia collision was situated at similar to 20 degrees N and took place by similar to 50Ma. KW - remagnetization KW - paleomagnetism applied to tectonics KW - rock and mineral magnetism KW - India-Asia collision Y1 - 2015 U6 - https://doi.org/10.1002/2014JB011599 SN - 2169-9313 SN - 2169-9356 VL - 120 IS - 1 SP - 42 EP - 66 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Peng, Tao A1 - Zhu, Ganghua A1 - Dong, Yunpeng A1 - Zeng, Junjie A1 - Li, Wei A1 - Guo, Weiwei A1 - Chen, Yong A1 - Duan, Maoli A1 - Hocher, Berthold A1 - Xie, Dinghua T1 - BMP4: a possible key factor in differentiation of auditory neuron-like cells from bone-derived mesenchymal stromal cells JF - Clinical laboratory : the peer reviewed journal for clinical laboratories and laboratories related to blood transfusion N2 - Background: Previous studies have shown that BMP4 may play an important part in the development of auditory neurons (ANs), which are degenerated in sensorineural hearing loss. However, whether BMP4 can promote sensory fate specification from mesenchymal stromal cells (MSCs) is unknown so far. Methods: MSCs isolated from Sprague-Dawley (SD) rats were confirmed by expression of MSC markers using flow cytometry and adipogenesis/osteogenesis using differentiation assays. MSCs treated with a complex of neurotrophic factors (BMP4 group and non-BMP4 group) were induced into auditory neuron-like cells, then the differences between the two groups were analyzed in morphological observation, cell growth curve, qRT-PCR, and immunofluorescence. Results: Flow cytometric analysis showed that the isolated cells expressed typical MSC surface markers. After adipogenic and osteogenic induction, the cells were stained by oil red O and Alizarin Red. The neuronal induced cells were in the growth plateau and had special forms of neurons. In the presence of BMP4, the inner ear genes NF-M, Neurog1, GluR4, NeuroD, Calretinin, NeuN, Tau, and GATA3 were up-regulated in MSCs. Conclusions: MSCs have the capacity to differentiate into auditory neuron-like cells in vitro. As an effective inducer, BMP4 may play a key role in transdifferentiation. KW - differentiation KW - auditory neurons KW - BMP4 Y1 - 2015 U6 - https://doi.org/10.7754/Clin.Lab.2015.150217 SN - 1433-6510 VL - 61 IS - 9 SP - 1171 EP - 1178 PB - Clin Lab Publ., Verl. Klinisches Labor CY - Heidelberg ER - TY - JOUR A1 - Clavier, Pierre A1 - Guo, Li A1 - Paycha, Sylvie A1 - Zhang, Bin T1 - Locality and renormalization: universal properties and integrals on trees JF - Journal of mathematical physics N2 - The purpose of this paper is to build an algebraic framework suited to regularize branched structures emanating from rooted forests and which encodes the locality principle. This is achieved by means of the universal properties in the locality framework of properly decorated rooted forests. These universal properties are then applied to derive the multivariate regularization of integrals indexed by rooted forests. We study their renormalization, along the lines of Kreimer's toy model for Feynman integrals. Y1 - 2020 U6 - https://doi.org/10.1063/1.5116381 SN - 0022-2488 SN - 1089-7658 VL - 61 IS - 2 PB - American Institute of Physics CY - College Park, Md. ER - TY - JOUR A1 - Vasishth, Shravan A1 - Chen, Zhong A1 - Li, Qiang A1 - Guo, Gueilan T1 - Processing chinese relative clauses - evidence for the subject-relative advantage JF - PLoS one N2 - A general fact about language is that subject relative clauses are easier to process than object relative clauses. Recently, several self-paced reading studies have presented surprising evidence that object relatives in Chinese are easier to process than subject relatives. We carried out three self-paced reading experiments that attempted to replicate these results. Two of our three studies found a subject-relative preference, and the third study found an object-relative advantage. Using a random effects bayesian meta-analysis of fifteen studies (including our own), we show that the overall current evidence for the subject-relative advantage is quite strong (approximate posterior probability of a subject-relative advantage given the data: 78-80%). We argue that retrieval/integration based accounts would have difficulty explaining all three experimental results. These findings are important because they narrow the theoretical space by limiting the role of an important class of explanation-retrieval/integration cost-at least for relative clause processing in Chinese. Y1 - 2013 U6 - https://doi.org/10.1371/journal.pone.0077006 SN - 1932-6203 VL - 8 IS - 10 PB - PLoS CY - San Fransisco ER -