TY  - JOUR
A1  - Himmel, Mirko
A1  - VanderVen, Peter F. M.
A1  - Stöcklein, Walter F. M.
A1  - Fürst, Dieter Oswald
T1  - The limits of promiscuity : isoform-specific dimerization of filamins
Y1  - 2003
ER  - 
TY  - JOUR
A1  - Obermann, Wolfgang
A1  - Gautel, Mathias
A1  - Steiner, F.
A1  - VanDerVen, Peter F. M.
A1  - Weber, Klaus
A1  - Fürst, Dieter Oswald
T1  - The structure of the sarcomeric M band : localization of defined domains of myomesin, M-protein, and the 250-kD carboxy-terminal region of titin by immunoelectron microscopy
Y1  - 1996
ER  - 
TY  - JOUR
A1  - Obermann, Wolfgang
A1  - VanDerVen, Peter F. M
A1  - Steiner, F.
A1  - Weber, Klaus
A1  - Fürst, Dieter Oswald
T1  - Mapping of a myosin binding domain and a regulatory phosphorylation site in M-protein, a structural protein of the sarcomeric M-band
Y1  - 1998
ER  - 
TY  - JOUR
A1  - Vorgerd, M.
A1  - vanderVen, Peter F. M.
A1  - Bruchertseifer, V.
A1  - Lowe, T.
A1  - Kley, R. A.
A1  - Schröder, Rolf
A1  - Lochmuller, H.
A1  - Himmel, Mirko
A1  - Koehler, K.
A1  - Fürst, Dieter Oswald
A1  - Huebner, A.
T1  - A mutation in the dimerization domain of filamin C causes a novel type of autosomal dominant myofibrillar myopathy
N2  - Myofibrillar myopathy (MFM) is a human disease that is characterized by focal myofibrillar destruction and pathological cytoplasmic protein aggregations. In an extended German pedigree with a novel form of MFM characterized by clinical features of a limb-girdle myopathy and morphological features of MFM, we identified a cosegregating, heterozygous nonsense mutation (8130G -> A; W2710X) in the filamin c gene ( FLNC) on chromosome 7q32.1. The mutation is the first found in FLNC and is localized in the dimerization domain of filamin c. Functional studies showed that, in the truncated mutant protein, this domain has a disturbed secondary structure that leads to the inability to dimerize properly. As a consequence of this malfunction, the muscle fibers of our patients display massive cytoplasmic aggregates containing filamin c and several Z-disk-associated and sarcolemmal proteins
Y1  - 2005
SN  - 0002-9297
ER  - 
TY  - JOUR
A1  - Kleuser, U.
A1  - Stöcklein, Walter F. M.
A1  - Pieper-Fürst, U.
A1  - Scheller, Frieder W.
T1  - Partikelverstärkte Oberflächenplasmonresonanz für die Quantifizierung von Matrix Metalloproteinase-2
Y1  - 2004
ER  - 
TY  - JOUR
A1  - Gehmlich, Katja
A1  - Geier, C.
A1  - Osterziel, Karl Joseph
A1  - VanderVen, Peter F. M.
A1  - Fürst, Dieter Oswald
T1  - Decreased interactions of mutant muscle LIM protein (MLP) with N-RAP and alpha-actinin and their implication for hypertrophic cardiomyopathy
N2  - Previous work has shown that mutations in muscle LIM protein (MLP) can cause hypertrophic cardiomyopathy (HCM). In order to gain an insight into the molecular basis of the disease phenotype, we analysed the binding characteristics of wild-type MLP and of the (C58G) mutant MLP that causes hypertrophic cardiomyopathy. We show that MLP can form a ternary complex with two of its previously documented myofibrillar ligand proteins, N-RAP and alpha-actinin, which indicates the presence of distinct, non-overlapping binding sites. Our data also show that, in comparison to wild-type MLP, the capacity of the mutated MLP protein to bind both N-RAP and alpha-actinin is significantly decreased. In addition, this single point mutation prevents zinc coordination and proper folding of the second zinc-finger in the first LIM domain, which consequently renders the protein less stable and more susceptible to proteolysis. The molecular basis for HCM-causing mutations in the MLP gene might therefore be an alteration in the equilibrium of interactions of the ternary complex MLP-N-RAP-alpha-actinin. This assumption is supported by the previous observation that in the pathological situation accompanied by MLP down regulation, cardiomyocytes try to compensate for the decreased stability of MLP protein by increasing the expression of its ligand N-RAP, which might finally result in the development of myocyte disarray that is characteristic of this disease
Y1  - 2004
SN  - 0302-766X
ER  - 
TY  - JOUR
A1  - Pieper-Fürst, U.
A1  - Kleuser, U.
A1  - Stöcklein, Walter F. M.
A1  - Warsinke, Axel
A1  - Scheller, Frieder W.
T1  - Detection of subicomolar concentrations of human matrix metalloproteinase-2 by an optical biosensor
N2  - We describe in this paper the development of a one-step sandwich assay for the highly sensitive and fast detection of human matrix metalloproteinase (MMP)-2 (EC 3.4.24.24), using surface plasmon resonance (SPR). For the assay, two ligands were selected: monoclonal anti-MMP-2 antibody Ab-2 and the tissue inhibitor of metalloproteinases (TIMP)-2. They were chosen on the basis of (1) their affinities to MMP-2, (2) the efficiency of immobilization to the sensor chip, (3) the efficiency of adsorption to colloidal gold, and (4) the stability of these protein-coated gold particles. The assay included mixing of MMP-2 with antibody Ab-2 adsorbed to colloidal gold with a diameter of about 20 rim and injection into the flowcell of the SPR instrument containing immobilized TIMP-2. By using colloidal gold particles an amplification factor of 114 and a detection limit of 0.5 pM for MMP-2 were obtained. The precision of the assay was high even at low analyte concentrations, the standard deviation being 8.3% for five determinations of 1 pM MMP- 2. No significant binding was observed with the structurally related MMP-9. The assay is far more sensitive and faster than commonly used methods for MMP-2 detection. As TIMP-bound MMP-2 is not detected by this method, the assay can be applied for measuring free MMP-2, reflecting the imbalance of free and inhibitor-bound enzyme in various pathological situations. (C) 2004 Elsevier Inc. All rights reserved
Y1  - 2004
ER  - 
TY  - JOUR
A1  - Pacholsky, Dirk
A1  - Vakeel, Padmanabhan
A1  - Himmel, Mirko
A1  - Lowe, T.
A1  - Stradal, T.
A1  - Rottner, K.
A1  - Fürst, Dieter Oswald
A1  - vanderVen, Peter F. M.
T1  - Xin repeats define a novel actin-binding motif
N2  - Xin is a protein that is expressed during early developmental stages of cardiac and skeletal muscles. Immunolocalization studies indicated a peripheral localization in embryonic mouse heart, where Xin localizes with beta- catenin and N-cadherin. In adult tissues, Xin is found primarily in the intercalated discs of cardiomyocytes and the myotendinous junctions of skeletal muscle cells, both specialized attachment sites of the myofibrillar ends to the sarcolemma. A large part of the Xin protein consists of unique 16 amino acid repeats with unknown function. We have investigated the characteristics of the Xin repeats by transfection experiments and actin-binding assays and ascertained that, upon expression in cultured cells, these repeats bind to and stabilize the actin-based cytoskeleton. In vitro co- sedimentation assays with skeletal muscle actin indicated that they not only directly bind actin filaments, but also have the capability of arranging microfilaments into networks that sediment upon low-speed centrifugation. Very similar repeats were also found in Xin-repeat protein 2' (XIRP2), a novel protein that seems to be expressed mainly in striated muscles. Human XIRP2 contains 28 Xin repeats with properties identical to those of Xin. We conclude that the Xin repeats define a novel, repetitive actin-binding motif present in at least two different muscle proteins. These Xin- repeat proteins therefore constitute the first two members of a novel family of actin-binding proteins
Y1  - 2004
SN  - 0021-9533
ER  - 
TY  - JOUR
A1  - Martinez-Chicharro, M.
A1  - Torrejon, J. M.
A1  - Oskinova, Lida
A1  - Furst, F.
A1  - Postnov, K.
A1  - Rodes-Roca, J. J.
A1  - Hainich, Rainer
A1  - Bodaghee, A.
T1  - Evidence of Compton cooling during an X-ray flare supports a neutron star nature of the compact object in 4U1700-37
JF  - Monthly notices of the Royal Astronomical Society
N2  - Based on new Chandra X-ray telescope data, we present empirical evidence of plasma Compton cooling during a flare in the non-pulsating massive X-ray binary 4U1700-37. This behaviour might be explained by quasi-spherical accretion on to a slowly rotating magnetized neutron star (NS). In quiescence, the NS in 4U1700-37 is surrounded by a hot radiatively cooling shell. Its presence is supported by the detection of mHz quasi-periodic oscillations likely produced by its convection cells. The high plasma temperature and the relatively low X-ray luminosity observed during the quiescence, point to a small emitting area similar to 1 km, compatible with a hotspot on an NS surface. The sudden transition from a radiative to a significantly more efficient Compton cooling regime triggers an episode of enhanced accretion resulting in a flare. During the flare, the plasma temperature drops quickly. The predicted luminosity for such transitions, similar to 3 x 10(35) erg s(-1), is very close to the luminosity of 4U1700-37 during quiescence. The transition may be caused by the accretion of a clump in the stellar wind of the donor star. Thus, a magnetized NS nature of the compact object is strongly favoured.
KW  - stars: individual: 4U1700-37
KW  - V*V884 Sco
KW  - X-rays: binaries
Y1  - 2017
U6  - https://doi.org/10.1093/mnrasl/slx165
SN  - 0035-8711
SN  - 1365-2966
VL  - 473
IS  - 1
SP  - L74
EP  - L78
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - VanDerLoop, Frank T. L.
A1  - VanDerVen, Peter F. M
A1  - Fürst, Dieter Oswald
A1  - Gautel, Mathias
A1  - VanEys, Guillaume
A1  - Ramaekers, Frans C. S.
T1  - Integration of titin into the sarcomeres of cultured differentiating human skeletal muscle cells
Y1  - 1996
ER  - 
TY  - JOUR
A1  - VanDerVen, Peter F. M
A1  - Obermann, Wolfgang
A1  - Weber, Klaus
A1  - Fürst, Dieter Oswald
T1  - Myomesin, M-protein and the structure of the sarcomeric M-band
Y1  - 1996
ER  - 
TY  - JOUR
A1  - Mayans, Olga
A1  - VanDerVen, Peter F. M
A1  - Wilmanns, Matthias
A1  - Mues, Alexander
A1  - Young, Paul
A1  - Fürst, Dieter Oswald
A1  - Wilmanns, Matthias
A1  - Gautel, Mathias
T1  - The structural basis of the activation of the serine kinase domain of the giant muscle protein titin during myofibrillogenesis
Y1  - 1998
ER  - 
TY  - JOUR
A1  - VanDerVen, Peter F. M
A1  - Fürst, Dieter Oswald
T1  - Expression of sarcomeric proteins and assembly of myofibrils in the putative myofibroblast cell line BHK-21/C13
Y1  - 1998
ER  - 
TY  - JOUR
A1  - Speel, Ernst J. M.
A1  - VanDerVen, Peter F. M.
A1  - Albrechts, Jozefa C. M.
A1  - Hopman, Anton H. N.
A1  - Fürst, Dieter Oswald
T1  - Chromosomal assignment of the human myomesin gene
Y1  - 1998
ER  - 
TY  - JOUR
A1  - VanDerVen, Peter F. M
A1  - Fürst, Dieter Oswald
T1  - Assembly of titin, myomesin and M-protein into the sarcomeric M-band in differentiating human skeletal muscle cells in vitro
Y1  - 1997
ER  - 
TY  - JOUR
A1  - Steiner, F.
A1  - Weber, Klaus
A1  - Fürst, Dieter Oswald
T1  - Structure and expression of the gene encoding murine M-protein, a sarcomere-specific member of the immunoglobulin superfamily
Y1  - 1998
ER  - 
TY  - JOUR
A1  - Mues, Alexander
A1  - VanDerVen, Peter F. M
A1  - Young, Paul
A1  - Fürst, Dieter Oswald
A1  - Gautel, Mathias
T1  - Two immunoglobulin-like domains of the Z-disk portion of titin interact in a conformation-dependent way with telethonin
Y1  - 1998
ER  - 
TY  - JOUR
A1  - Speel, Ernst J. M.
A1  - VanDerVen, Peter F. M.
A1  - Albrechts, Jozefa C. M.
A1  - Ramaekers, Frans C. S.
A1  - Fürst, Dieter Oswald
A1  - Hopman, Anton H. N.
T1  - Assignment of the human gene for the sarcomeric M-band protein myomesin (MYOM1) to 18p11.31-p11.32
Y1  - 1998
ER  - 
TY  - JOUR
A1  - Schröder, Rolf
A1  - VanDerVen, Peter F. M.
A1  - Warlo, Irene
A1  - Schumann, H.
A1  - Fürst, Dieter Oswald
A1  - Blümke, Ingmar
A1  - Goebel, Hans H.
A1  - Schmidt, M. C.
A1  - Hatzfeld, Mechthild
T1  - A member of the armadillo multigene family, is a constituent of sarcomeric I-bands in human skeletal muscle
Y1  - 2000
ER  - 
TY  - JOUR
A1  - Schröder, Rolf
A1  - Fürst, Dieter Oswald
A1  - Klasen, Christian
A1  - Reiman, Jens
A1  - Herrmann, Harald
A1  - VanDerVen, Peter F. M.
T1  - The association of plectin with Z-discs is a prerequisite for the formation of the intermyofibrillar desmin cytoskeleton
Y1  - 2000
ER  - 
TY  - JOUR
A1  - VanDerVen, Peter F. M.
A1  - Bartsch, Jörg
A1  - Gautel, Mathias
A1  - Jokusch, Harald
A1  - Fürst, Dieter Oswald
T1  - A functional knock-out of titin results in defective myofibril assembly
Y1  - 2000
ER  - 
TY  - JOUR
A1  - VanDerVen, Peter F. M
A1  - Obermann, Wolfgang
A1  - Lemke, Britt
A1  - Gautel, Mathias
A1  - Weber, Klaus
A1  - Fürst, Dieter Oswald
T1  - The characterization of muscle filamin isoforms suggests a possible role of ABP-L/gamma-filamin in sarcomeric Z- disc formation
Y1  - 2000
ER  - 
TY  - JOUR
A1  - Steiner, F.
A1  - Fürst, Dieter Oswald
A1  - Weber, Klaus
T1  - M-band proteins myomesin und skelemin are encoded by a single gene: analysis of its organization and expression
Y1  - 1999
ER  - 
TY  - JOUR
A1  - Fürst, Dieter Oswald
A1  - Obermann, Wolfgang
A1  - VanDerVen, Peter F. M
T1  - Structure and assembly of the sarcomeric M-band
Y1  - 1999
ER  - 
TY  - JOUR
A1  - Schröder, Rolf
A1  - Warlo, Irene
A1  - Herrmann, Harald
A1  - VanDerVen, Peter F. M
A1  - Klasen, Christian
A1  - Blümke, Ingmar
A1  - Mundegar, Rustam R.
A1  - Fürst, Dieter Oswald
A1  - Göbel, Hans H.
A1  - Magin, Thomas
T1  - Immunogold EM reveals a close association of plectin and the desmin cytoskeleton in human skeletal muscle
Y1  - 1999
ER  - 
TY  - JOUR
A1  - VanDerVen, Peter F. M.
A1  - Speel, Ernst J. M.
A1  - Albrechts, Jozefa C. M.
A1  - Ramaekers, Frans C. S.
A1  - Hopman, Anton H. N.
A1  - Fürst, Dieter Oswald
T1  - Chromosomal assignment of the human gene for endosarcomeric cytoskeletal M-protein (MYOM2) to 8p23.3
Y1  - 1999
ER  - 
TY  - JOUR
A1  - VanDerVen, Peter F. M.
A1  - Speel, Ernst J. M.
A1  - Albrechts, Jozefa C. M.
A1  - Ramaekers, Frans C. S.
A1  - Hopman, Anton H. N.
A1  - Fürst, Dieter Oswald
T1  - Assignment of the human gene for endosarcomeric cytoskeletal M-protein (MYOM2) to 8p23.3
Y1  - 1999
ER  - 
TY  - JOUR
A1  - Oskinova, Lida
A1  - Bik, A.
A1  - Mas-Hesse, J. M.
A1  - Hayes, M.
A1  - Adamo, A.
A1  - Östlin, Göran
A1  - Fürst, F.
A1  - Otí-Floranes, H.
T1  - ULX contribution to stellar feedback
BT  - an intermediate-mass black hole candidate and the population of ULXs in the low-metallicity starburst galaxy ESO338-4
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Context. X-ray radiation from accreting compact objects is an important part of stellar feedback. The metal-poor galaxy ESO 338-4 has experienced vigorous starburst during the last <40 Myr and contains some of the most massive super star clusters in the nearby Universe. Given its starburst age and its star-formation rate, ESO 338-4 is one of the most efficient nearby manufactures of neutron stars and black holes, hence providing an excellent laboratory for feedback studies. Aims. We aim to use X-ray observations with the largest modern X-ray telescopes XMM-Newton and Chandra to unveil the most luminous accreting neutron stars and black holes in ESO 338-4. Methods. We compared X-ray images and spectra with integral field spectroscopic observations in the optical to constrain the nature of strong X-ray emitters. Results. X-ray observations uncover three ultraluminous X-ray sources (ULXs) in ESO 338-4. The brightest among them, ESO 338 X-1, has X-ray luminosity in excess of 10(40) erg s(-1). We speculate that ESO 338-4 X-1 is powered by accretion on an intermediate-mass (greater than or similar to 300 M-circle dot)black hole. We show that X-ray radiation from ULXs and hot superbubbles strongly contributes to He II ionization and general stellar feedback in this template starburst galaxy.
KW  - galaxies: dwarf
KW  - galaxies: individual: ESO 338-4
KW  - X-rays: binaries
KW  - X-rays: ISM
Y1  - 2019
U6  - https://doi.org/10.1051/0004-6361/201935414
SN  - 1432-0746
VL  - 627
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Sander, Andreas Alexander Christoph
A1  - Fürst, F.
A1  - Kretschmar, P.
A1  - Oskinova, Lida
A1  - Todt, Helge Tobias
A1  - Hainich, Rainer
A1  - Shenar, Tomer
A1  - Hamann, Wolf-Rainer
T1  - Coupling hydrodynamics with comoving frame radiative transfer
BT  - Stellar wind stratification in the high-mass X-ray binary Vela X-1
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Aims. To gain a realistic picture of the donor star in Vela X-1, we constructed a hydrodynamically consistent atmosphere model describing the wind stratification while properly reproducing the observed donor spectrum. To investigate how X-ray illumination affects the stellar wind, we calculated additional models for different X-ray luminosity regimes. Methods. We used the recently updated version of the Potsdam Wolf-Rayet code to consistently solve the hydrodynamic equation together with the statistical equations and the radiative transfer. Results. The wind flow in Vela X-1 is driven by ions from various elements, with Fe III and S III leading in the outer wind. The model-predicted mass-loss rate is in line with earlier empirical studies. The mass-loss rate is almost unaffected by the presence of the accreting NS in the wind. The terminal wind velocity is confirmed at u(infinity) approximate to 600 km s(-1). On the other hand, the wind velocity in the inner region where the NS is located is only approximate to 100 km s(-1), which is not expected on the basis of a standard beta-velocity law. In models with an enhanced level of X-rays, the velocity field in the outer wind can be altered. If the X-ray flux is too high, the acceleration breaks down because the ionization increases. Conclusions. Accounting for radiation hydrodynamics, our Vela X-1 donor atmosphere model reveals a low wind speed at the NS location, and it provides quantitative information on wind driving in this important HMXB.
KW  - stars: mass-loss
KW  - stars: winds, outflows
KW  - stars: early-type
KW  - stars: atmospheres
KW  - stars: massive
KW  - X-rays: binaries
Y1  - 2018
U6  - https://doi.org/10.1051/0004-6361/201731575
SN  - 1432-0746
VL  - 610
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Torrejon, J. M.
A1  - Reig, Pablo
A1  - Fürst, F.
A1  - Martinez-Chicharro, M.
A1  - Postnov, K.
A1  - Oskinova, Lida
T1  - NuSTAR rules out a cyclotron line in the accreting magnetar candidate 4U2206+54
JF  - Monthly notices of the Royal Astronomical Society
N2  - Based on our new NuSTAR X-ray telescope data, we rule out any cyclotron line up to 60 keV in the spectra of the high-mass X-ray binary 4U2206+54. In particular, we do not find any evidence of the previously claimed line around 30 keV, independently of the source flux, along the spin pulse. The spin period has increased significantly, since the last observation, up to 5750 +/- 10 s, confirming the rapid spin-down rate (nu)over dot = -1.8 x 10(-14) Hz s(-1). This behaviour might be explained by the presence of a strongly magnetized neutron star (B-s > several times 10(13) G) accreting from the slow wind of its main-sequence O9.5 companion.
KW  - Stars: individual: 4U2206+54, BD+53 2790
KW  - X-rays: binaries
Y1  - 2018
U6  - https://doi.org/10.1093/mnras/sty1628
SN  - 0035-8711
SN  - 1365-2966
VL  - 479
IS  - 3
SP  - 3366
EP  - 3372
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - VanderVen, Peter F. M.
A1  - Ehler, Elisabeth
A1  - Vakeel, Padmanabhan
A1  - Eulitz, Stefan
A1  - Schenk, Jörg A.
A1  - Milting, Hendrik
A1  - Micheel, Burkhard
A1  - Fürst, Dieter Oswald
T1  - Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/ VASP
N2  - Filamin c is the predominantly expressed filamin isoform in striated muscles. It is localized in myofibrillar Z- discs, where it binds FATZ and myotilin, and in myotendinous junctions and intercalated discs. Here, we identify Xin, the protein encoded by the human gene 'cardiomyopathy associated 1' (CMYA1) as filamin c binding partner at these specialized structures where the ends of myofibrils are attached to the sarcolemma. Xin directly binds the EVH1 domain proteins Mena and VASP. In the adult heart, Xin and Mena/VASP colocalize with filamin c in intercalated discs. In cultured cardiomyocytes, the proteins also localize in the nonstriated part of myofibrils, where sarcomeres are assembled and an extensive reorganization of the actin cytoskeleton occurs. Unusual intraexonic splicing events result in the existence of three Xin isoforms that associate differentially with its ligands. The identification of the complex filamin c-Xin-Mena/VASP provides a first glance on the role of Xin in the molecular mechanisms involved in developmental and adaptive remodeling of the actin cytoskeleton during cardiac morphogenesis and sarcomere assembly. (c) 2006 Elsevier Inc. All rights reserved
Y1  - 2006
U6  - https://doi.org/10.1016/j.yexcr.2006.03.015
ER  - 
TY  - JOUR
A1  - Irrgang, Andreas
A1  - Geier, Stephan
A1  - Heber, Ulrich
A1  - Kupfer, Thomas
A1  - Fürst, F.
T1  - PG 1610+062: a runaway B star challenging classical ejection mechanisms
JF  - Astronomy and astrophysics : an international weekly journal
N2  - Hypervelocity stars are rare objects, mostly main-sequence (MS) B stars, traveling so fast that they will eventually escape from the Milky Way. Recently, it has been shown that the popular Hills mechanism, in which a binary system is disrupted via a close encounter with the supermassive black hole at the Galactic center, may not be their only ejection mechanism. The analyses of Gaia data ruled out a Galactic center origin for some of them, and instead indicated that they are extreme disk runaway stars ejected at velocities exceeding the predicted limits of classical scenarios (dynamical ejection from star clusters or binary supernova ejection). We present the discovery of a new extreme disk runaway star, PG 1610+062, which is a slowly pulsating B star bright enough to be studied in detail. A quantitative analysis of spectra taken with ESI at the Keck Observatory revealed that PG 1610+062 is a late B-type MS star of 4–5 M⊙ with low projected rotational velocity. Abundances (C, N, O, Ne, Mg, Al, Si, S, Ar, and Fe) were derived differentially with respect to the normal B star HD 137366 and indicate that PG 1610+062 is somewhat metal rich. A kinematic analysis, based on our spectrophotometric distance (17.3 kpc) and on proper motions from Gaia’s second data release, shows that PG 1610+062 was probably ejected from the Carina-Sagittarius spiral arm at a velocity of 550 ± 40 km s−1, which is beyond the classical limits. Accordingly, the star is in the top five of the most extreme MS disk runaway stars and is only the second among the five for which the chemical composition is known.
KW  - stars: abundances
KW  - stars: individual: HD 137366
KW  - stars: kinematics and dynamics
KW  - stars: individual: PG 1610+062
KW  - stars: early-type
Y1  - 2019
U6  - https://doi.org/10.1051/0004-6361/201935429
SN  - 1432-0746
VL  - 628
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - JOUR
A1  - Raynaud, F
A1  - Jond-Necand, C
A1  - Marcilhac, Anne
A1  - Fürst, Dieter Oswald
A1  - Benyamin, Yves
T1  - Calpain 1-gamma filamin interaction in muscle cells : a possible in situ regulation by PKC-alpha
Y1  - 2006
ER  - 
TY  - JOUR
A1  - Raynaud, F
A1  - Jond-Necand, C
A1  - Marcilhac, Anne
A1  - Fürst, Dieter Oswald
A1  - Benyamin, Yves
T1  - Calpain 1-gamma filamin interaction in muscle cells :a possible in situ regulation by PKC-alpha
Y1  - 2006
ER  -