TY  - JOUR
A1  - Hofman, Maarten P. G.
A1  - Hayward, M. W.
A1  - Heim, M.
A1  - Marchand, P.
A1  - Rolandsen, C. M.
A1  - Mattisson, Jenny
A1  - Urbano, F.
A1  - Heurich, M.
A1  - Mysterud, A.
A1  - Melzheimer, J.
A1  - Morellet, N.
A1  - Voigt, Ulrich
A1  - Allen, B. L.
A1  - Gehr, Benedikt
A1  - Rouco Zufiaurre, Carlos
A1  - Ullmann, Wiebke
A1  - Holand, O.
A1  - Jorgensen, n H.
A1  - Steinheim, G.
A1  - Cagnacci, F.
A1  - Kroeschel, M.
A1  - Kaczensky, P.
A1  - Buuveibaatar, B.
A1  - Payne, J. C.
A1  - Palmegiani, I
A1  - Jerina, K.
A1  - Kjellander, P.
A1  - Johansson, O.
A1  - LaPoint, S.
A1  - Bayrakcismith, R.
A1  - Linnell, J. D. C.
A1  - Zaccaroni, M.
A1  - Jorge, M. L. S.
A1  - Oshima, J. E. F.
A1  - Songhurst, A.
A1  - Fischer, C.
A1  - Mc Bride, R. T.
A1  - Thompson, J. J.
A1  - Streif, S.
A1  - Sandfort, R.
A1  - Bonenfant, Christophe
A1  - Drouilly, M.
A1  - Klapproth, M.
A1  - Zinner, Dietmar
A1  - Yarnell, Richard
A1  - Stronza, A.
A1  - Wilmott, L.
A1  - Meisingset, E.
A1  - Thaker, Maria
A1  - Vanak, A. T.
A1  - Nicoloso, S.
A1  - Graeber, R.
A1  - Said, S.
A1  - Boudreau, M. R.
A1  - Devlin, A.
A1  - Hoogesteijn, R.
A1  - May-Junior, J. A.
A1  - Nifong, J. C.
A1  - Odden, J.
A1  - Quigley, H. B.
A1  - Tortato, F.
A1  - Parker, D. M.
A1  - Caso, A.
A1  - Perrine, J.
A1  - Tellaeche, C.
A1  - Zieba, F.
A1  - Zwijacz-Kozica, T.
A1  - Appel, C. L.
A1  - Axsom, I
A1  - Bean, W. T.
A1  - Cristescu, B.
A1  - Periquet, S.
A1  - Teichman, K. J.
A1  - Karpanty, S.
A1  - Licoppe, A.
A1  - Menges, V
A1  - Black, K.
A1  - Scheppers, Thomas L.
A1  - Schai-Braun, S. C.
A1  - Azevedo, F. C.
A1  - Lemos, F. G.
A1  - Payne, A.
A1  - Swanepoel, L. H.
A1  - Weckworth, B.
A1  - Berger, A.
A1  - Bertassoni, Alessandra
A1  - McCulloch, G.
A1  - Sustr, P.
A1  - Athreya, V
A1  - Bockmuhl, D.
A1  - Casaer, J.
A1  - Ekori, A.
A1  - Melovski, D.
A1  - Richard-Hansen, C.
A1  - van de Vyver, D.
A1  - Reyna-Hurtado, R.
A1  - Robardet, E.
A1  - Selva, N.
A1  - Sergiel, A.
A1  - Farhadinia, M. S.
A1  - Sunde, P.
A1  - Portas, R.
A1  - Ambarli, Hüseyin
A1  - Berzins, R.
A1  - Kappeler, P. M.
A1  - Mann, G. K.
A1  - Pyritz, L.
A1  - Bissett, C.
A1  - Grant, T.
A1  - Steinmetz, R.
A1  - Swedell, Larissa
A1  - Welch, R. J.
A1  - Armenteras, D.
A1  - Bidder, O. R.
A1  - Gonzalez, T. M.
A1  - Rosenblatt, A.
A1  - Kachel, S.
A1  - Balkenhol, N.
T1  - Right on track?
BT  - Performance of satellite telemetry in terrestrial wildlife research
JF  - PLoS one
N2  - Satellite telemetry is an increasingly utilized technology in wildlife research, and current devices can track individual animal movements at unprecedented spatial and temporal resolutions. However, as we enter the golden age of satellite telemetry, we need an in-depth understanding of the main technological, species-specific and environmental factors that determine the success and failure of satellite tracking devices across species and habitats. Here, we assess the relative influence of such factors on the ability of satellite telemetry units to provide the expected amount and quality of data by analyzing data from over 3,000 devices deployed on 62 terrestrial species in 167 projects worldwide. We evaluate the success rate in obtaining GPS fixes as well as in transferring these fixes to the user and we evaluate failure rates. Average fix success and data transfer rates were high and were generally better predicted by species and unit characteristics, while environmental characteristics influenced the variability of performance. However, 48% of the unit deployments ended prematurely, half of them due to technical failure. Nonetheless, this study shows that the performance of satellite telemetry applications has shown improvements over time, and based on our findings, we provide further recommendations for both users and manufacturers.
Y1  - 2019
U6  - https://doi.org/10.1371/journal.pone.0216223
SN  - 1932-6203
VL  - 14
IS  - 5
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Fischer, Stephanie S.
A1  - Kempe, Daniela S.
A1  - Leibrock, Christina B.
A1  - Rexhepaj, Rexhep
A1  - Siraskar, Balasaheb
A1  - Boini, Krishna M.
A1  - Ackermann, Teresa F.
A1  - Foeller, Michael
A1  - Hocher, Berthold
A1  - Rosenblatt, Kevin P.
A1  - Kuro-o, Makoto
A1  - Lang, Florian
T1  - Hyperaldosteronism in Klotho-deficient mice
N2  - Klotho is a membrane protein participating in the inhibitory effect of FGF23 on the formation of 1,25- dihydroxyvitamin-D-3 [1,25(OH)(2)D-3]. It participates in the regulation of renal tubular phosphate reabsorption and stimulates renal tubular Ca2+ reabsorption. Klotho hypomorphic mice (klotho(hm)) suffer from severe growth deficit, rapid aging, and early death, events largely reversed by a vitamin D-deficient diet. The present study explored the role of Klotho deficiency in mineral and electrolyte metabolism. To this end, klothohm mice and wild-type mice (klotho(+/+)) were subjected to a normal (D+) or vitamin D-deficient (D-) diet or to a vitamin D-deficient diet for 4 wk and then to a normal diet (D-/+). At the age of 8 wk, body weight was significantly lower in klotho(hm)D(+) mice than in klotho(+/ +)D(+) mice, klotho(hm)D(-) mice, and klotho(hm)D(-/+) mice. Plasma concentrations of 1,25(OH)(2)D-3, adrenocorticotropic hormone (ACTH), antidiuretic hormone (ADH), and aldosterone were significantly higher in klotho(hm)D(+) mice than in klotho(+/+)D(+) mice. Plasma volume was significantly smaller in klotho(hm)D(-/+) mice, and plasma urea, Ca2+, phosphate and Na+, but not K+ concentrations were significantly higher in klotho(hm)D(+) mice than in klotho(+/+)D(+) mice. The differences were partially abrogated by a vitamin D-deficient diet. Moreover, the hyperaldosteronism was partially reversed by Ca2+-deficient diet. Ussing chamber experiments revealed a marked increase in amiloride-sensitive current across the colonic epithelium, pointing to enhanced epithelial sodium channel (ENaC) activity. A salt-deficient diet tended to decrease and a salt-rich diet significantly increased the life span of klotho(hm)D(+) mice. In conclusion, the present observation disclose that the excessive formation of 1,25(OH)(2)D-3 in Klotho-deficient mice results in extracellular volume depletion, which significantly contributes to the shortening of life span.
Y1  - 2010
UR  - http://ajprenal.physiology.org/
U6  - https://doi.org/10.1152/ajprenal.00233.2010
SN  - 1931-857X
ER  - 
TY  - JOUR
A1  - Gonzalez Manrique, Sergio Javier
A1  - Kuckein, Christoph
A1  - Pastor Yabar, A.
A1  - Collados Vera, M.
A1  - Denker, Carsten
A1  - Fischer, C. E.
A1  - Gömöry, P.
A1  - Diercke, Andrea
A1  - Gonzalez, N. Bello
A1  - Schlichenmaier, R.
A1  - Balthasar, H.
A1  - Berkefeld, T.
A1  - Feller, A.
A1  - Hoch, S.
A1  - Hofmann, A.
A1  - Kneer, F.
A1  - Lagg, A.
A1  - Nicklas, H.
A1  - Orozco Suarez, D.
A1  - Schmidt, D.
A1  - Schmidt, W.
A1  - Sigwarth, M.
A1  - Sobotka, M.
A1  - Solanki, S. K.
A1  - Soltau, D.
A1  - Staude, J.
A1  - Strassmeier, Klaus G.
A1  - Verma, Meetu
A1  - Volkmer, R.
A1  - von der Lühe, O.
A1  - Waldmann, T.
T1  - Fitting peculiar spectral profiles in He I 10830 angstrom absorption features
JF  - Astronomische Nachrichten = Astronomical notes
N2  - The new generation of solar instruments provides better spectral, spatial, and temporal resolution for a better understanding of the physical processes that take place on the Sun. Multiple-component profiles are more commonly observed with these instruments. Particularly, the He i 10830 triplet presents such peculiar spectral profiles, which give information on the velocity and magnetic fine structure of the upper chromosphere. The purpose of this investigation is to describe a technique to efficiently fit the two blended components of the He i 10830 triplet, which are commonly observed when two atmospheric components are located within the same resolution element. The observations used in this study were taken on 2015 April 17 with the very fast spectroscopic mode of the GREGOR Infrared Spectrograph (GRIS) attached to the 1.5-m GREGOR solar telescope, located at the Observatorio del Teide, Tenerife, Spain. We apply a double-Lorentzian fitting technique using Levenberg-Marquardt least-squares minimization. This technique is very simple and much faster than inversion codes. Line-of-sight Doppler velocities can be inferred for a whole map of pixels within just a few minutes. Our results show sub-and supersonic downflow velocities of up to 32 km s(-1) for the fast component in the vicinity of footpoints of filamentary structures. The slow component presents velocities close to rest. (C) 2016 WILEY-VCH Verlag GmbH& Co. KGaA, Weinheim
KW  - Sun: chromosphere
KW  - methods: data analysis
KW  - techniques: spectroscopic
KW  - line: profiles
Y1  - 2016
U6  - https://doi.org/10.1002/asna.201512433
SN  - 0004-6337
SN  - 1521-3994
VL  - 337
SP  - 1057
EP  - 1063
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Koenig, Julian
A1  - Abler, Birgit
A1  - Agartz, Ingrid
A1  - akerstedt, Torbjorn
A1  - Andreassen, Ole A.
A1  - Anthony, Mia
A1  - Baer, Karl-Juergen
A1  - Bertsch, Katja
A1  - Brown, Rebecca C.
A1  - Brunner, Romuald
A1  - Carnevali, Luca
A1  - Critchley, Hugo D.
A1  - Cullen, Kathryn R.
A1  - de Geus, Eco J. C.
A1  - de la Cruz, Feliberto
A1  - Dziobek, Isabel
A1  - Ferger, Marc D.
A1  - Fischer, Hakan
A1  - Flor, Herta
A1  - Gaebler, Michael
A1  - Gianaros, Peter J.
A1  - Giummarra, Melita J.
A1  - Greening, Steven G.
A1  - Guendelman, Simon
A1  - Heathers, James A. J.
A1  - Herpertz, Sabine C.
A1  - Hu, Mandy X.
A1  - Jentschke, Sebastian
A1  - Kaess, Michael
A1  - Kaufmann, Tobias
A1  - Klimes-Dougan, Bonnie
A1  - Koelsch, Stefan
A1  - Krauch, Marlene
A1  - Kumral, Deniz
A1  - Lamers, Femke
A1  - Lee, Tae-Ho
A1  - Lekander, Mats
A1  - Lin, Feng
A1  - Lotze, Martin
A1  - Makovac, Elena
A1  - Mancini, Matteo
A1  - Mancke, Falk
A1  - Mansson, Kristoffer N. T.
A1  - Manuck, Stephen B.
A1  - Mather, Mara
A1  - Meeten, Frances
A1  - Min, Jungwon
A1  - Mueller, Bryon
A1  - Muench, Vera
A1  - Nees, Frauke
A1  - Nga, Lin
A1  - Nilsonne, Gustav
A1  - Ordonez Acuna, Daniela
A1  - Osnes, Berge
A1  - Ottaviani, Cristina
A1  - Penninx, Brenda W. J. H.
A1  - Ponzio, Allison
A1  - Poudel, Govinda R.
A1  - Reinelt, Janis
A1  - Ren, Ping
A1  - Sakaki, Michiko
A1  - Schumann, Andy
A1  - Sorensen, Lin
A1  - Specht, Karsten
A1  - Straub, Joana
A1  - Tamm, Sandra
A1  - Thai, Michelle
A1  - Thayer, Julian F.
A1  - Ubani, Benjamin
A1  - van Der Mee, Denise J.
A1  - van Velzen, Laura S.
A1  - Ventura-Bort, Carlos
A1  - Villringer, Arno
A1  - Watson, David R.
A1  - Wei, Luqing
A1  - Wendt, Julia
A1  - Schreiner, Melinda Westlund
A1  - Westlye, Lars T.
A1  - Weymar, Mathias
A1  - Winkelmann, Tobias
A1  - Wu, Guo-Rong
A1  - Yoo, Hyun Joo
A1  - Quintana, Daniel S.
T1  - Cortical thickness and resting-state cardiac function across the lifespan
BT  - a cross-sectional pooled mega-analysis
JF  - Psychophysiology : journal of the Society for Psychophysiological Research
N2  - Understanding the association between autonomic nervous system [ANS] function and brain morphology across the lifespan provides important insights into neurovisceral mechanisms underlying health and disease. Resting-state ANS activity, indexed by measures of heart rate [HR] and its variability [HRV] has been associated with brain morphology, particularly cortical thickness [CT]. While findings have been mixed regarding the anatomical distribution and direction of the associations, these inconsistencies may be due to sex and age differences in HR/HRV and CT. Previous studies have been limited by small sample sizes, which impede the assessment of sex differences and aging effects on the association between ANS function and CT. To overcome these limitations, 20 groups worldwide contributed data collected under similar protocols of CT assessment and HR/HRV recording to be pooled in a mega-analysis (N = 1,218 (50.5% female), mean age 36.7 years (range: 12-87)). Findings suggest a decline in HRV as well as CT with increasing age. CT, particularly in the orbitofrontal cortex, explained additional variance in HRV, beyond the effects of aging. This pattern of results may suggest that the decline in HRV with increasing age is related to a decline in orbitofrontal CT. These effects were independent of sex and specific to HRV; with no significant association between CT and HR. Greater CT across the adult lifespan may be vital for the maintenance of healthy cardiac regulation via the ANS-or greater cardiac vagal activity as indirectly reflected in HRV may slow brain atrophy. Findings reveal an important association between CT and cardiac parasympathetic activity with implications for healthy aging and longevity that should be studied further in longitudinal research.
KW  - aging
KW  - autonomic nervous system
KW  - cortical thickness
KW  - heart rate
KW  - heart
KW  - rate variability
KW  - sex
Y1  - 2020
U6  - https://doi.org/10.1111/psyp.13688
SN  - 0048-5772
SN  - 1469-8986
VL  - 58
IS  - 7
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Sorkau, Elisabeth
A1  - Boch, Steffen
A1  - Boeddinghaus, Runa S.
A1  - Bonkowski, Michael
A1  - Fischer, Markus
A1  - Kandeler, Ellen
A1  - Klaus, Valentin H.
A1  - Kleinebecker, Till
A1  - Marhan, Sven
A1  - Müller, Jörg
A1  - Prati, Daniel
A1  - Schoening, Ingo
A1  - Schrumpf, Marion
A1  - Weinert, Jan
A1  - Oelmann, Yvonne
T1  - The role of soil chemical properties, land use and plant diversity for microbial phosphorus in forest and grassland soils
JF  - Journal of plant nutrition and soil science = Zeitschrift für Pflanzenernährung und Bodenkunde
N2  - Management intensity modifies soil properties, e.g., organic carbon (C-org) concentrations and soil pH with potential feedbacks on plant diversity. These changes might influence microbial P concentrations (P-mic) in soil representing an important component of the Pcycle. Our objectives were to elucidate whether abiotic and biotic variables controlling P-mic concentrations in soil are the same for forests and grasslands, and to assess the effect of region and management on P-mic concentrations in forest and grassland soils as mediated by the controlling variables. In three regions of Germany, Schwabische Alb, Hanich-Dun, and Schorfheide-Chorin, we studied forest and grassland plots (each n=150) differing in plant diversity and land-use intensity. In contrast to controls of microbial biomass carbon (C-mic), P-mic was strongly influenced by soil pH, which in turn affected phosphorus (P) availability and thus microbial Puptake in forest and grassland soils. Furthermore, P-mic concentrations in forest and grassland soils increased with increasing plant diversity. Using structural equation models, we could show that soil C-org is the profound driver of plant diversity effects on P-mic in grasslands. For both forest and grassland, we found regional differences in P-mic attributable to differing environmental conditions (pH, soil moisture). Forest management and tree species showed no effect on P-mic due to a lack of effects on controlling variables (e.g., C-org). We also did not find management effects in grassland soils which might be caused by either compensation of differently directed effects across sites or by legacy effects of former fertilization constraining the relevance of actual practices. We conclude that variables controlling P-mic or C-mic in soil differ in part and that regional differences in controlling variables are more important for P-mic in soil than those induced by management.
KW  - age class forest
KW  - land-use intensity
KW  - meadow
KW  - microbes
KW  - pasture
KW  - unmanaged forest
Y1  - 2018
U6  - https://doi.org/10.1002/jpln.201700082
SN  - 1436-8730
SN  - 1522-2624
VL  - 181
IS  - 2
SP  - 185
EP  - 197
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - GEN
A1  - Kulkova, Elena S.
A1  - Fischer, Martin H.
T1  - Idioms in the World
BT  - A Focus on Processing
T2  - Postprints der Universität Potsdam Humanwissenschaftliche Reihe
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 561 
KW  - embodiment
KW  - figurative language
KW  - metaphor
KW  - idiom
KW  - processing
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-435704
SN  - 1866-8364
IS  - 561
ER  - 
TY  - JOUR
A1  - Lobmaier, Janek S.
A1  - Fischer, Martin H.
T1  - Facial Feedback Affects Perceived Intensity but Not Quality of Emotional Expressions
JF  - Brain Sciences
N2  - Motivated by conflicting evidence in the literature, we re-assessed the role of facial feedback when detecting quantitative or qualitative changes in others’ emotional expressions. Fifty-three healthy adults observed self-paced morph sequences where the emotional facial expression either changed quantitatively (i.e., sad-to-neutral, neutral-to-sad, happy-to-neutral, neutral-to-happy) or qualitatively (i.e. from sad to happy, or from happy to sad). Observers held a pen in their own mouth to induce smiling or frowning during the detection task. When morph sequences started or ended with neutral expressions we replicated a congruency effect: Happiness was perceived longer and sooner while smiling; sadness was perceived longer and sooner while frowning. Interestingly, no such congruency effects occurred for transitions between emotional expressions. These results suggest that facial feedback is especially useful when evaluating the intensity of a facial expression, but less so when we have to recognize which emotion our counterpart is expressing.
KW  - embodied cognition
KW  - emotional expression
KW  - emotion recognition
KW  - facial feedback
KW  - face morphing
Y1  - 2015
U6  - https://doi.org/10.3390/brainsci5030357
SN  - 2076-3425
VL  - 5
IS  - 3
SP  - 357
EP  - 368
PB  - MDPI AG
CY  - Basel
ER  - 
TY  - GEN
A1  - Lobmaier, Janek S.
A1  - Fischer, Martin H.
T1  - Facial Feedback Affects Perceived Intensity but Not Quality of Emotional Expressions
N2  - Motivated by conflicting evidence in the literature, we re-assessed the role of facial feedback when detecting quantitative or qualitative changes in others’ emotional expressions. Fifty-three healthy adults observed self-paced morph sequences where the emotional facial expression either changed quantitatively (i.e., sad-to-neutral, neutral-to-sad, happy-to-neutral, neutral-to-happy) or qualitatively (i.e. from sad to happy, or from happy to sad). Observers held a pen in their own mouth to induce smiling or frowning during the detection task. When morph sequences started or ended with neutral expressions we replicated a congruency effect: Happiness was perceived longer and sooner while smiling; sadness was perceived longer and sooner while frowning. Interestingly, no such congruency effects occurred for transitions between emotional expressions. These results suggest that facial feedback is especially useful when evaluating the intensity of a facial expression, but less so when we have to recognize which emotion our counterpart is expressing.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 302 
KW  - embodied cognition
KW  - emotional expression
KW  - emotion recognition
KW  - facial feedback
KW  - face morphing
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-96428
SP  - 357
EP  - 368
ER  - 
TY  - JOUR
A1  - Fischer, Markus
A1  - Wipf, S.
A1  - Rixen, C.
A1  - Stöckli, V.
T1  - Effects of ski piste preparation on alpine vegetation
N2  - 1. Ski resorts increasingly affect alpine ecosystems through enlargement of ski pistes, machine-grading of ski piste areas and increasing use of artificial snow. 2. In 12 Swiss alpine ski resorts, we investigated the effects of ski piste management on vegetation structure and composition using a pairwise design of 38 plots on ski pistes and 38 adjacent plots off-piste. 3. Plots on ski pistes had lower species richness and productivity, and lower abundance and cover of woody plants and early flowering species, than reference plots. Plots on machine-graded pistes had higher indicator values for nutrients and light, and lower vegetation cover, productivity, species diversity and abundance of early flowering and woody plants. Time since machine-grading did not mitigate the impacts of machine-grading, even for those plots where revegetation had been attempted by sowing. 4. The longer artificial snow had been used on ski pistes (2-15 years), the higher the moisture and nutrient indicator values. Longer use also affected species composition by increasing the abundance of woody plants, snowbed species and late-flowering species, and decreasing wind-edge species. 5. Synthesis and applications. All types of ski piste management cause deviations from the natural structure and composition of alpine vegetation, and lead to lower plant species diversity. Machine-grading causes particularly severe and lasting impacts on alpine vegetation, which are mitigated neither by time nor by revegetation measures. The impacts of artificial snow increase with the period of time since it was first applied to ski piste vegetation. Extensive machine-grading and snow production should be avoided, especially in areas where nutrient and water input are a concern. Ski pistes should not be established in areas where the alpine vegetation has a high conservation value
Y1  - 2005
SN  - 0021-8901
ER  - 
TY  - BOOK
A1  - Riemenschneider, Dieter
A1  - Sarkowsky, K.
A1  - Stroh, S.
A1  - Schulze-Engler, F.
A1  - Matzke, C.
A1  - Meier, A.
A1  - Wegner, M.
A1  - Stein, Mark
A1  - Fischer, J.
A1  - Riemenschneider, K.
T1  - Postcolonial theory : the emergence of a critical discourse ; a selected and annotated bibliography
T3  - ZAA Studies : language literature culture
Y1  - 2004
SN  - 3-86057-746-8
VL  - 17
PB  - Stauffenburg-Verl.
CY  - Tübingen
ER  - 
TY  - JOUR
A1  - Holzmeier, Fabian
A1  - Wolf, Thomas J. A.
A1  - Gienger, Christian
A1  - Wagner, Isabella
A1  - Bozek, J.
A1  - Nandi, S.
A1  - Nicolas, C.
A1  - Fischer, Ingo
A1  - Gühr, Markus
A1  - Fink, Reinhold F.
T1  - Normal and resonant Auger spectroscopy of isocyanic acid, HNCO
JF  - The journal of chemical physics : bridges a gap between journals of physics and journals of chemistr
N2  - In this paper, we investigate HNCO by resonant and nonresonant Auger electron spectroscopy at the K-edges of carbon, nitrogen, and oxygen, employing soft X-ray synchrotron radiation. In comparison with the isosteric but linear CO2 molecule, spectra of the bent HNCO molecule are similar but more complex due to its reduced symmetry, wherein the degeneracy of the π-orbitals is lifted. Resonant Auger electron spectra are presented at different photon energies over the first core-excited 1s → 10a′ resonance. All Auger electron spectra are assigned based on ab initio configuration interaction computations combined with the one-center approximation for Auger intensities and moment theory to consider vibrational motion. The calculated spectra were scaled by a newly introduced energy scaling factor, and generally, good agreement is found between experiment and theory for normal as well as resonant Auger electron spectra. A comparison of resonant Auger spectra with nonresonant Auger structures shows a slight broadening as well as a shift of the former spectra between −8 and −9 eV due to the spectating electron. Since HNCO is a small molecule and contains the four most abundant atoms of organic molecules, the reported Auger electron decay spectra will provide a benchmark for further theoretical approaches in the computation of core electron spectra.
Y1  - 2018
U6  - https://doi.org/10.1063/1.5030621
SN  - 0021-9606
SN  - 1089-7690
VL  - 149
IS  - 3
PB  - American Institute of Physics
CY  - Melville
ER  - 
TY  - GEN
A1  - Hische, Manuela
A1  - Larhlimi, Abdelhalim
A1  - Schwarz, Franziska
A1  - Fischer-Rosinský, Antje
A1  - Bobbert, Thomas
A1  - Assmann, Anke
A1  - Catchpole, Gareth S.
A1  - Pfeiffer, Andreas F. H.
A1  - Willmitzer, Lothar
A1  - Selbig, Joachim
A1  - Spranger, Joachim
T1  - A distinct metabolic signature predictsdevelopment of fasting plasma glucose
T2  - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe
N2  - Background

High blood glucose and diabetes are amongst the conditions causing the greatest losses in years of healthy life worldwide. Therefore, numerous studies aim to identify reliable risk markers for development of impaired glucose metabolism and type 2 diabetes. However, the molecular basis of impaired glucose metabolism is so far insufficiently understood. The development of so called 'omics' approaches in the recent years promises to identify molecular markers and to further understand the molecular basis of impaired glucose metabolism and type 2 diabetes. Although univariate statistical approaches are often applied, we demonstrate here that the application of multivariate statistical approaches is highly recommended to fully capture the complexity of data gained using high-throughput methods.

Methods

We took blood plasma samples from 172 subjects who participated in the prospective Metabolic Syndrome Berlin Potsdam follow-up study (MESY-BEPO Follow-up). We analysed these samples using Gas Chromatography coupled with Mass Spectrometry (GC-MS), and measured 286 metabolites. Furthermore, fasting glucose levels were measured using standard methods at baseline, and after an average of six years. We did correlation analysis and built linear regression models as well as Random Forest regression models to identify metabolites that predict the development of fasting glucose in our cohort.

Results

We found a metabolic pattern consisting of nine metabolites that predicted fasting glucose development with an accuracy of 0.47 in tenfold cross-validation using Random Forest regression. We also showed that adding established risk markers did not improve the model accuracy. However, external validation is eventually desirable. Although not all metabolites belonging to the final pattern are identified yet, the pattern directs attention to amino acid metabolism, energy metabolism and redox homeostasis.

Conclusions

We demonstrate that metabolites identified using a high-throughput method (GC-MS) perform well in predicting the development of fasting plasma glucose over several years. Notably, not single, but a complex pattern of metabolites propels the prediction and therefore reflects the complexity of the underlying molecular mechanisms. This result could only be captured by application of multivariate statistical approaches. Therefore, we highly recommend the usage of statistical methods that seize the complexity of the information given by high-throughput methods.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 850 
KW  - prediction
KW  - fasting glucose
KW  - type 2 diabetes
KW  - metabolomics
KW  - plasma
KW  - random forest
KW  - metabolite
KW  - regression
KW  - biomarker
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-427400
SN  - 1866-8372
IS  - 850
ER  - 
TY  - JOUR
A1  - Uhlmann, Manuela
A1  - Korup, Oliver
A1  - Huggel, Christian
A1  - Fischer, Luzia
A1  - Kargel, Jeffrey S.
T1  - Supra-glacial deposition and flux of catastrophic rock-slope failure debris, south-central Alaska
JF  - Earth surface processes and landforms : the journal of the British Geomorphological Research Group
N2  - The ongoing debate over the effects of global environmental change on Earth's cryosphere calls for detailed knowledge about process rates and their variability in cold environments. In this context, appraisals of the coupling between glacier dynamics and para-glacial erosion rates in tectonically active mountains remain rare. We contribute to filling this knowledge gap and present an unprecedented regional-scale inventory of supra-glacial sediment flux and hillslope erosion rates inferred from an analysis of 123 large (> 0 center dot 1km2) catastrophic bedrock landslides that fell onto glaciers in the Chugach Mountains, Alaska, as documented by satellite images obtained between 1972 to 2008. Assuming these supra-glacial landslide deposits to be passive strain markers we infer minimum decadal-scale sediment yields of 190 to 7400tkm-2yr-1 for a given glacier-surface cross-section impacted by episodic rock-slope failure. These rates compare to reported fluvial sediment yields in many mountain rivers, but are an order of magnitude below the extreme sediment yields measured at the snouts of Alaskan glaciers, indicating that the bulk of debris discharged derives from en-glacial, sub-glacial or ice-proximal sources. We estimate an average minimum para-glacial erosion rate by large, episodic rock-slope failures at 0 center dot 5-0 center dot 7mmyr-1 in the Chugach Mountains over a 50-yr period, with earthquakes likely being responsible for up to 73% of this rate. Though ranking amongst the highest decadal landslide erosion rates for this size of study area worldwide, our inferred rates of hillslope erosion in the Chugach Mountains remain an order of magnitude below the pace of extremely rapid glacial sediment export and glacio-isostatic surface uplift previously reported from the region.
KW  - glacier
KW  - landslide
KW  - erosion rate
KW  - sediment yield
KW  - Alaska
Y1  - 2013
U6  - https://doi.org/10.1002/esp.3311
SN  - 0197-9337
VL  - 38
IS  - 7
SP  - 675
EP  - 682
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - INPR
A1  - Murray, Wayne S.
A1  - Fischer, Martin H.
A1  - Tatler, Benjamin W.
T1  - Serial and parallel processes in eye movement control - current controversies and future directions
T2  - The quarterly journal of experimental psychology
N2  - In this editorial for the Special Issue on Serial and Parallel Processing in Reading we explore the background to the current debate concerning whether the word recognition processes in reading are strictly serialsequential or take place in an overlapping parallel fashion. We consider the history of the controversy and some of the underlying assumptions, together with an analysis of the types of evidence and arguments that have been adduced to both sides of the debate, concluding that both accounts necessarily presuppose some weakening of, or elasticity in, the eyemind assumption. We then consider future directions, both for reading research and for scene viewing, and wrap up the editorial with a brief overview of the following articles and their conclusions.
KW  - Serial and parallel
KW  - Eye movements
KW  - Reading
KW  - Scene perception
KW  - Modality
KW  - Modelling
KW  - Eyemind assumption
KW  - Decoupling
KW  - Alan Kennedy
Y1  - 2013
U6  - https://doi.org/10.1080/17470218.2012.759979
SN  - 1747-0218
VL  - 66
IS  - 3
SP  - 417
EP  - 428
PB  - Wiley
CY  - Hove
ER  - 
TY  - JOUR
A1  - Pfestorf, H.
A1  - Weiss, L.
A1  - Müller, J.
A1  - Boch, Steffen
A1  - Socher, S. A.
A1  - Prati, Daniel
A1  - Schöning, Ingo
A1  - Weisser, W.
A1  - Fischer, M.
A1  - Jeltsch, Florian
T1  - Community mean traits as additional indicators to monitor effects of land-use intensity On grassland plant diversity
JF  - Perspectives in plant ecology, evolution and systematics
N2  - Semi-natural grasslands, biodiversity hotspots in Central-Europe, suffer from the cessation of traditional land-use. Amount and intensity of these changes challenge current monitoring frameworks typically based on classic indicators such as selected target species or diversity indices. Indicators based on plant functional traits provide an interesting extension since they reflect ecological strategies at individual and ecological processes at community levels. They typically show convergent responses to gradients of land-use intensity over scales and regions, are more directly related to environmental drivers than diversity components themselves and enable detecting directional changes in whole community dynamics. However, probably due to their labor- and cost intensive assessment in the field, they have been rarely applied as indicators so far.
 Here we suggest overcoming these limitations by calculating indicators with plant traits derived from online accessible databases. Aiming to provide a minimal trait set to monitor effects of land-use intensification on plant diversity we investigated relationships between 12 community mean traits, 2 diversity indices and 6 predictors of land-use intensity within grassland communities of 3 different regions in Germany (part of the German 'Biodiversity Exploratory' research network). By standardization of traits and diversity measures, use of null models and linear mixed models we confirmed (i) strong links between functional community composition and plant diversity, (ii) that traits are closely related to land-use intensity, and (iii) that functional indicators are equally, or even more sensitive to land-use intensity than traditional diversity indices. The deduced trait set consisted of 5 traits, i.e., specific leaf area (SLA), leaf dry matter content (LDMC), seed release height, leaf distribution, and onset of flowering. These database derived traits enable the early detection of changes in community structure indicative for future diversity loss. As an addition to current monitoring measures they allow to better link environmental drivers to processes controlling community dynamics.
KW  - Biodiversity Exploratories
KW  - Biological conservation
KW  - (Semi-natural) Grasslands
KW  - Plant functional traits
KW  - Indicators
KW  - Land-use intensity
Y1  - 2013
U6  - https://doi.org/10.1016/j.ppees.2012.10.003
SN  - 1433-8319
VL  - 15
IS  - 1
SP  - 1
EP  - 11
PB  - Elsevier
CY  - Jena
ER  - 
TY  - JOUR
A1  - Stumpe, Joachim
A1  - Sakhno, O.
A1  - Gritsai, Y.
A1  - Rosenhauer, R.
A1  - Fischer, Th.
A1  - Rutloh, Michael
A1  - Schaal, F.
A1  - Weidenfeld, S.
A1  - Jetter, M.
A1  - Michler, P.
A1  - Pruss, C.
A1  - Osten, W.
T1  - Active and passive LC based polarization elements
JF  - Molecular crystals and liquid crystals
N2  - Passive and active polarization elements were created by surface and bulk photo-alignment of LCs, reactive LCs, photo-sensitive LCP and photo-curable monomer/LC composites. The use of different photo-sensitive liquid crystalline materials for the development of highly anisotropic elements with high spatial resolution and stability or, alternatively, fast switch ability will be discussed. Photo-active and voltage tunable polarization and diffraction elements are presented. For active micro-optic application a photo-addressed patterned retarder was created. Electrically switchable diffraction gratings were generated by interference exposure of photo-curable LC composites at room temperature characterized by droplet free morphology. These polarization sensitive diffraction elements are characterized be excellent optical properties and low switching times.
KW  - electrically switchable gratings.
KW  - diffractive elements
KW  - polymer/LC composites
KW  - switchable retarder
KW  - polarization gratings
KW  - Polarization elements
Y1  - 2014
U6  - https://doi.org/10.1080/15421406.2014.917503
SN  - 1542-1406
SN  - 1563-5287
VL  - 594
IS  - 1
SP  - 140
EP  - 149
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Fischer, Anna S.
T1  - Horomedon und Laokoon
BT  - Raum und Zeit in plastischer Kunst und Poesie bei Maksimilian A. Vološin und Gotthold Ephraim Lessing
JF  - Texturen – Identitäten – Theorien : Ergebnisse des Arbeitstreffens des Jungen Forums Slavistische Literaturwissenschaft in Trier 2010
N2  - - Horomedon - Laokoon - Raum und Zeit - Plastische Künste - Fazit
Y1  - 2011
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-58976
SP  - 425
EP  - 441
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Verma, Meetu
A1  - Denker, Carsten
A1  - Böhm, F.
A1  - Balthasar, H.
A1  - Fischer, C. E.
A1  - Kuckein, Christoph
A1  - Gonzalez, N. Bello
A1  - Berkefeld, T.
A1  - Collados Vera, M.
A1  - Diercke, Andrea
A1  - Feller, A.
A1  - Gonzalez Manrique, Sergio Javier
A1  - Hofmann, A.
A1  - Lagg, A.
A1  - Nicklas, H.
A1  - Orozco Suarez, D.
A1  - Pator Yabar, A.
A1  - Rezaei, R.
A1  - Schlichenmaier, R.
A1  - Schmidt, D.
A1  - Schmidt, W.
A1  - Sigwarth, M.
A1  - Sobotka, M.
A1  - Solanki, S. K.
A1  - Soltau, D.
A1  - Staude, J.
A1  - Strassmeier, Klaus G.
A1  - Volkmer, R.
A1  - von der Lühe, O.
A1  - Waldmann, T.
T1  - Flow and magnetic field properties in the trailing sunspots of active region NOAA 12396
JF  - Astronomische Nachrichten = Astronomical notes
N2  - Improved measurements of the photospheric and chromospheric three-dimensional magnetic and flow fields are crucial for a precise determination of the origin and evolution of active regions. We present an illustrative sample of multi-instrument data acquired during a two-week coordinated observing campaign in August 2015 involving, among others, the GREGOR solar telescope (imaging and near-infrared spectroscopy) and the space missions Solar Dynamics Observatory (SDO) and Interface Region Imaging Spectrograph (IRIS). The observations focused on the trailing part of active region NOAA 12396 with complex polarity inversion lines and strong intrusions of opposite polarity flux. The GREGOR Infrared Spectrograph (GRIS) provided Stokes IQUV spectral profiles in the photospheric Si i.1082.7 nm line, the chromospheric He I lambda 1083.0 nm triplet, and the photospheric Ca I lambda 1083.9 nm line. Carefully calibrated GRIS scans of the active region provided maps of Doppler velocity and magnetic field at different atmospheric heights. We compare quick-look maps with those obtained with the " Stokes Inversions based on Response functions" (SIR) code, which furnishes deeper insight into the magnetic properties of the region. We find supporting evidence that newly emerging flux and intruding opposite polarity flux are hampering the formation of penumbrae, i.e., a penumbra fully surrounding a sunspot is only expected after cessation of flux emergence in proximity to the sunspots. (C) 2016 WILEY-VCH Verlag GmbH& Co.KGaA, Weinheim
KW  - Sun: magnetic fields
KW  - sunspots
KW  - methods: data analysis
KW  - techniques: polarimetric
KW  - techniques: spectroscopic
Y1  - 2016
U6  - https://doi.org/10.1002/asna.201612447
SN  - 0004-6337
SN  - 1521-3994
VL  - 337
SP  - 1090
EP  - 1098
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Achilles, E. I. S.
A1  - Fink, G. R.
A1  - Fischer, Martin H.
A1  - Dovern, A.
A1  - Held, A.
A1  - Timpert, D. C.
A1  - Schroeter, C.
A1  - Schuetz, K.
A1  - Kloetzsch, C.
A1  - Weiss, P. H.
T1  - Effect of meaning on apraxic finger imitation deficits
JF  - Neuropsychologia : an international journal in behavioural and cognitive neuroscience
N2  - Apraxia typically results from left-hemispheric (LH), but also from right-hemispheric (RH) stroke, and often impairs gesture imitation. Especially in LH stroke, it is important to differentiate apraxia-induced gesture imitation deficits from those due to co-morbid aphasia and associated semantic deficits, possibly influencing the imitation of meaningful (MF) gestures. To explore this issue, we first investigated if the 10 supposedly meaningless (ML) gestures of a widely used finger imitation test really carry no meaning, or if the test also contains MF gestures, by asking healthy subjects (n=45) to classify these gestures as MF or ML. Most healthy subjects (98%) classified three of the 10 gestures as clearly MF. Only two gestures were considered predominantly ML. We next assessed how imitation in stroke patients (255 LH, 113 RH stroke) is influenced by gesture meaning and how aphasia influences imitation of LH stroke patients (n=208). All patients and especially patients with imitation deficits (17% of LH, 27% of RH stroke patients) imitated MF gestures significantly better than ML gestures. Importantly, meaningfulness-scores of all 10 gestures significantly predicted imitation scores of patients with imitation deficits. Furthermore, especially in LH stroke patients with imitation deficits, the severity of aphasia significantly influenced the imitation of MF, but not ML gestures. Our findings in a large patient cohort support current cognitive models of imitation and strongly suggest that ML gestures are particularly sensitive to detect imitation deficits while minimising confounding effects of aphasia which affect the imitation of MF gestures in LH stroke patients. (C) 2015 Elsevier Ltd. All rights reserved.
KW  - Apraxia
KW  - Meaning
KW  - Cognitive models of imitation
Y1  - 2016
U6  - https://doi.org/10.1016/j.neuropsychologia.2015.12.022
SN  - 0028-3932
SN  - 1873-3514
VL  - 82
SP  - 74
EP  - 83
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - GEN
A1  - Lobmaier, Janek S.
A1  - Fischer, Martin H.
T1  - Facial feedback affects perceived intensity but not quality of emotional expressions
N2  - Motivated by conflicting evidence in the literature, we re-assessed the role of facial feedback when detecting quantitative or qualitative changes in others’ emotional expressions. Fifty-three healthy adults observed self-paced morph sequences where the emotional facial expression either changed quantitatively (i.e., sad-to-neutral, neutral-to-sad, happy-to-neutral, neutral-to-happy) or qualitatively (i.e. from sad to happy, or from happy to sad). Observers held a pen in their own mouth to induce smiling or frowning during the detection task. When morph sequences started or ended with neutral expressions we replicated a congruency effect: Happiness was perceived longer and sooner while smiling; sadness was perceived longer and sooner while frowning. Interestingly, no such congruency effects occurred for transitions between emotional expressions. These results suggest that facial feedback is especially useful when evaluating the intensity of a facial expression, but less so when we have to recognize which emotion our counterpart is expressing.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 335 
KW  - embodied cognition
KW  - emotional expression
KW  - emotion recognition
KW  - facial feedback
KW  - face morphing
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-400157
ER  -