TY  - JOUR
A1  - Wuttke, Matthias
A1  - Li, Yong
A1  - Li, Man
A1  - Sieber, Karsten B.
A1  - Feitosa, Mary F.
A1  - Gorski, Mathias
A1  - Tin, Adrienne
A1  - Wang, Lihua
A1  - Chu, Audrey Y.
A1  - Hoppmann, Anselm
A1  - Kirsten, Holger
A1  - Giri, Ayush
A1  - Chai, Jin-Fang
A1  - Sveinbjornsson, Gardar
A1  - Tayo, Bamidele O.
A1  - Nutile, Teresa
A1  - Fuchsberger, Christian
A1  - Marten, Jonathan
A1  - Cocca, Massimiliano
A1  - Ghasemi, Sahar
A1  - Xu, Yizhe
A1  - Horn, Katrin
A1  - Noce, Damia
A1  - Van der Most, Peter J.
A1  - Sedaghat, Sanaz
A1  - Yu, Zhi
A1  - Akiyama, Masato
A1  - Afaq, Saima
A1  - Ahluwalia, Tarunveer Singh
A1  - Almgren, Peter
A1  - Amin, Najaf
A1  - Arnlov, Johan
A1  - Bakker, Stephan J. L.
A1  - Bansal, Nisha
A1  - Baptista, Daniela
A1  - Bergmann, Sven
A1  - Biggs, Mary L.
A1  - Biino, Ginevra
A1  - Boehnke, Michael
A1  - Boerwinkle, Eric
A1  - Boissel, Mathilde
A1  - Böttinger, Erwin
A1  - Boutin, Thibaud S.
A1  - Brenner, Hermann
A1  - Brumat, Marco
A1  - Burkhardt, Ralph
A1  - Butterworth, Adam S.
A1  - Campana, Eric
A1  - Campbell, Archie
A1  - Campbell, Harry
A1  - Canouil, Mickael
A1  - Carroll, Robert J.
A1  - Catamo, Eulalia
A1  - Chambers, John C.
A1  - Chee, Miao-Ling
A1  - Chee, Miao-Li
A1  - Chen, Xu
A1  - Cheng, Ching-Yu
A1  - Cheng, Yurong
A1  - Christensen, Kaare
A1  - Cifkova, Renata
A1  - Ciullo, Marina
A1  - Concas, Maria Pina
A1  - Cook, James P.
A1  - Coresh, Josef
A1  - Corre, Tanguy
A1  - Sala, Cinzia Felicita
A1  - Cusi, Daniele
A1  - Danesh, John
A1  - Daw, E. Warwick
A1  - De Borst, Martin H.
A1  - De Grandi, Alessandro
A1  - De Mutsert, Renee
A1  - De Vries, Aiko P. J.
A1  - Degenhardt, Frauke
A1  - Delgado, Graciela
A1  - Demirkan, Ayse
A1  - Di Angelantonio, Emanuele
A1  - Dittrich, Katalin
A1  - Divers, Jasmin
A1  - Dorajoo, Rajkumar
A1  - Eckardt, Kai-Uwe
A1  - Ehret, Georg
A1  - Elliott, Paul
A1  - Endlich, Karlhans
A1  - Evans, Michele K.
A1  - Felix, Janine F.
A1  - Foo, Valencia Hui Xian
A1  - Franco, Oscar H.
A1  - Franke, Andre
A1  - Freedman, Barry I.
A1  - Freitag-Wolf, Sandra
A1  - Friedlander, Yechiel
A1  - Froguel, Philippe
A1  - Gansevoort, Ron T.
A1  - Gao, He
A1  - Gasparini, Paolo
A1  - Gaziano, J. Michael
A1  - Giedraitis, Vilmantas
A1  - Gieger, Christian
A1  - Girotto, Giorgia
A1  - Giulianini, Franco
A1  - Gogele, Martin
A1  - Gordon, Scott D.
A1  - Gudbjartsson, Daniel F.
A1  - Gudnason, Vilmundur
A1  - Haller, Toomas
A1  - Hamet, Pavel
A1  - Harris, Tamara B.
A1  - Hartman, Catharina A.
A1  - Hayward, Caroline
A1  - Hellwege, Jacklyn N.
A1  - Heng, Chew-Kiat
A1  - Hicks, Andrew A.
A1  - Hofer, Edith
A1  - Huang, Wei
A1  - Hutri-Kahonen, Nina
A1  - Hwang, Shih-Jen
A1  - Ikram, M. Arfan
A1  - Indridason, Olafur S.
A1  - Ingelsson, Erik
A1  - Ising, Marcus
A1  - Jaddoe, Vincent W. V.
A1  - Jakobsdottir, Johanna
A1  - Jonas, Jost B.
A1  - Joshi, Peter K.
A1  - Josyula, Navya Shilpa
A1  - Jung, Bettina
A1  - Kahonen, Mika
A1  - Kamatani, Yoichiro
A1  - Kammerer, Candace M.
A1  - Kanai, Masahiro
A1  - Kastarinen, Mika
A1  - Kerr, Shona M.
A1  - Khor, Chiea-Chuen
A1  - Kiess, Wieland
A1  - Kleber, Marcus E.
A1  - Koenig, Wolfgang
A1  - Kooner, Jaspal S.
A1  - Korner, Antje
A1  - Kovacs, Peter
A1  - Kraja, Aldi T.
A1  - Krajcoviechova, Alena
A1  - Kramer, Holly
A1  - Kramer, Bernhard K.
A1  - Kronenberg, Florian
A1  - Kubo, Michiaki
A1  - Kuhnel, Brigitte
A1  - Kuokkanen, Mikko
A1  - Kuusisto, Johanna
A1  - La Bianca, Martina
A1  - Laakso, Markku
A1  - Lange, Leslie A.
A1  - Langefeld, Carl D.
A1  - Lee, Jeannette Jen-Mai
A1  - Lehne, Benjamin
A1  - Lehtimaki, Terho
A1  - Lieb, Wolfgang
A1  - Lim, Su-Chi
A1  - Lind, Lars
A1  - Lindgren, Cecilia M.
A1  - Liu, Jun
A1  - Liu, Jianjun
A1  - Loeffler, Markus
A1  - Loos, Ruth J. F.
A1  - Lucae, Susanne
A1  - Lukas, Mary Ann
A1  - Lyytikainen, Leo-Pekka
A1  - Magi, Reedik
A1  - Magnusson, Patrik K. E.
A1  - Mahajan, Anubha
A1  - Martin, Nicholas G.
A1  - Martins, Jade
A1  - Marz, Winfried
A1  - Mascalzoni, Deborah
A1  - Matsuda, Koichi
A1  - Meisinger, Christa
A1  - Meitinger, Thomas
A1  - Melander, Olle
A1  - Metspalu, Andres
A1  - Mikaelsdottir, Evgenia K.
A1  - Milaneschi, Yuri
A1  - Miliku, Kozeta
A1  - Mishra, Pashupati P.
A1  - Program, V. A. Million Veteran
A1  - Mohlke, Karen L.
A1  - Mononen, Nina
A1  - Montgomery, Grant W.
A1  - Mook-Kanamori, Dennis O.
A1  - Mychaleckyj, Josyf C.
A1  - Nadkarni, Girish N.
A1  - Nalls, Mike A.
A1  - Nauck, Matthias
A1  - Nikus, Kjell
A1  - Ning, Boting
A1  - Nolte, Ilja M.
A1  - Noordam, Raymond
A1  - Olafsson, Isleifur
A1  - Oldehinkel, Albertine J.
A1  - Orho-Melander, Marju
A1  - Ouwehand, Willem H.
A1  - Padmanabhan, Sandosh
A1  - Palmer, Nicholette D.
A1  - Palsson, Runolfur
A1  - Penninx, Brenda W. J. H.
A1  - Perls, Thomas
A1  - Perola, Markus
A1  - Pirastu, Mario
A1  - Pirastu, Nicola
A1  - Pistis, Giorgio
A1  - Podgornaia, Anna I.
A1  - Polasek, Ozren
A1  - Ponte, Belen
A1  - Porteous, David J.
A1  - Poulain, Tanja
A1  - Pramstaller, Peter P.
A1  - Preuss, Michael H.
A1  - Prins, Bram P.
A1  - Province, Michael A.
A1  - Rabelink, Ton J.
A1  - Raffield, Laura M.
A1  - Raitakari, Olli T.
A1  - Reilly, Dermot F.
A1  - Rettig, Rainer
A1  - Rheinberger, Myriam
A1  - Rice, Kenneth M.
A1  - Ridker, Paul M.
A1  - Rivadeneira, Fernando
A1  - Rizzi, Federica
A1  - Roberts, David J.
A1  - Robino, Antonietta
A1  - Rossing, Peter
A1  - Rudan, Igor
A1  - Rueedi, Rico
A1  - Ruggiero, Daniela
A1  - Ryan, Kathleen A.
A1  - Saba, Yasaman
A1  - Sabanayagam, Charumathi
A1  - Salomaa, Veikko
A1  - Salvi, Erika
A1  - Saum, Kai-Uwe
A1  - Schmidt, Helena
A1  - Schmidt, Reinhold
A1  - Ben Schottker, 
A1  - Schulz, Christina-Alexandra
A1  - Schupf, Nicole
A1  - Shaffer, Christian M.
A1  - Shi, Yuan
A1  - Smith, Albert V.
A1  - Smith, Blair H.
A1  - Soranzo, Nicole
A1  - Spracklen, Cassandra N.
A1  - Strauch, Konstantin
A1  - Stringham, Heather M.
A1  - Stumvoll, Michael
A1  - Svensson, Per O.
A1  - Szymczak, Silke
A1  - Tai, E-Shyong
A1  - Tajuddin, Salman M.
A1  - Tan, Nicholas Y. Q.
A1  - Taylor, Kent D.
A1  - Teren, Andrej
A1  - Tham, Yih-Chung
A1  - Thiery, Joachim
A1  - Thio, Chris H. L.
A1  - Thomsen, Hauke
A1  - Thorleifsson, Gudmar
A1  - Toniolo, Daniela
A1  - Tonjes, Anke
A1  - Tremblay, Johanne
A1  - Tzoulaki, Ioanna
A1  - Uitterlinden, Andre G.
A1  - Vaccargiu, Simona
A1  - Van Dam, Rob M.
A1  - Van der Harst, Pim
A1  - Van Duijn, Cornelia M.
A1  - Edward, Digna R. Velez
A1  - Verweij, Niek
A1  - Vogelezang, Suzanne
A1  - Volker, Uwe
A1  - Vollenweider, Peter
A1  - Waeber, Gerard
A1  - Waldenberger, Melanie
A1  - Wallentin, Lars
A1  - Wang, Ya Xing
A1  - Wang, Chaolong
A1  - Waterworth, Dawn M.
A1  - Bin Wei, Wen
A1  - White, Harvey
A1  - Whitfield, John B.
A1  - Wild, Sarah H.
A1  - Wilson, James F.
A1  - Wojczynski, Mary K.
A1  - Wong, Charlene
A1  - Wong, Tien-Yin
A1  - Xu, Liang
A1  - Yang, Qiong
A1  - Yasuda, Masayuki
A1  - Yerges-Armstrong, Laura M.
A1  - Zhang, Weihua
A1  - Zonderman, Alan B.
A1  - Rotter, Jerome I.
A1  - Bochud, Murielle
A1  - Psaty, Bruce M.
A1  - Vitart, Veronique
A1  - Wilson, James G.
A1  - Dehghan, Abbas
A1  - Parsa, Afshin
A1  - Chasman, Daniel I.
A1  - Ho, Kevin
A1  - Morris, Andrew P.
A1  - Devuyst, Olivier
A1  - Akilesh, Shreeram
A1  - Pendergrass, Sarah A.
A1  - Sim, Xueling
A1  - Boger, Carsten A.
A1  - Okada, Yukinori
A1  - Edwards, Todd L.
A1  - Snieder, Harold
A1  - Stefansson, Kari
A1  - Hung, Adriana M.
A1  - Heid, Iris M.
A1  - Scholz, Markus
A1  - Teumer, Alexander
A1  - Kottgen, Anna
A1  - Pattaro, Cristian
T1  - A catalog of genetic loci associated with kidney function from analyses of a million individuals
JF  - Nature genetics
N2  - Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these,147 were likely to be relevant for kidney function on the basis of associations with the alternative kidney function marker blood urea nitrogen (n = 416,178). Pathway and enrichment analyses, including mouse models with renal phenotypes, support the kidney as the main target organ. A genetic risk score for lower eGFR was associated with clinically diagnosed CKD in 452,264 independent individuals. Colocalization analyses of associations with eGFR among 783,978 European-ancestry individuals and gene expression across 46 human tissues, including tubulo-interstitial and glomerular kidney compartments, identified 17 genes differentially expressed in kidney. Fine-mapping highlighted missense driver variants in 11 genes and kidney-specific regulatory variants. These results provide a comprehensive priority list of molecular targets for translational research.
Y1  - 2019
U6  - https://doi.org/10.1038/s41588-019-0407-x
SN  - 1061-4036
SN  - 1546-1718
VL  - 51
IS  - 6
SP  - 957
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - JOUR
A1  - Abdo, A. A.
A1  - Ackermann, Margit
A1  - Ajello, M.
A1  - Allafort, A. J.
A1  - Baldini, L.
A1  - Ballet, J.
A1  - Barbiellini, G.
A1  - Baring, M. G.
A1  - Bastieri, D.
A1  - Bechtol, K. C.
A1  - Bellazzini, R.
A1  - Berenji, B.
A1  - Blandford, R. D.
A1  - Bloom, E. D.
A1  - Bonamente, E.
A1  - Borgland, A. W.
A1  - Bouvier, A.
A1  - Brandt, T. J.
A1  - Bregeon, Johan
A1  - Brez, A.
A1  - Brigida, M.
A1  - Bruel, P.
A1  - Buehler, R.
A1  - Buson, S.
A1  - Caliandro, G. A.
A1  - Cameron, R. A.
A1  - Cannon, A.
A1  - Caraveo, P. A.
A1  - Carrigan, Svenja
A1  - Casandjian, J. M.
A1  - Cavazzuti, E.
A1  - Cecchi, C.
A1  - Celik, O.
A1  - Charles, E.
A1  - Chekhtman, A.
A1  - Cheung, C. C.
A1  - Chiang, J.
A1  - Ciprini, S.
A1  - Claus, R.
A1  - Cohen-Tanugi, J.
A1  - Conrad, Jan
A1  - Cutini, S.
A1  - Dermer, C. D.
A1  - de Palma, F.
A1  - do Couto e Silva, E.
A1  - Drell, P. S.
A1  - Dubois, R.
A1  - Dumora, D.
A1  - Favuzzi, C.
A1  - Fegan, S. J.
A1  - Ferrara, E. C.
A1  - Focke, W. B.
A1  - Fortin, P.
A1  - Frailis, M.
A1  - Fuhrmann, L.
A1  - Fukazawa, Y.
A1  - Funk, S.
A1  - Fusco, P.
A1  - Gargano, F.
A1  - Gasparrini, D.
A1  - Gehrels, N.
A1  - Germani, S.
A1  - Giglietto, N.
A1  - Giordano, F.
A1  - Giroletti, M.
A1  - Glanzman, T.
A1  - Godfrey, G.
A1  - Grenier, I. A.
A1  - Guillemot, L.
A1  - Guiriec, S.
A1  - Hayashida, M.
A1  - Hays, E.
A1  - Horan, D.
A1  - Hughes, R. E.
A1  - Johannesson, G.
A1  - Johnson, A. S.
A1  - Johnson, W. N.
A1  - Kadler, M.
A1  - Kamae, T.
A1  - Katagiri, H.
A1  - Kataoka, J.
A1  - Knoedlseder, J.
A1  - Kuss, M.
A1  - Lande, J.
A1  - Latronico, L.
A1  - Lee, S. -H.
A1  - Lemoine-Goumard, M.
A1  - Longo, F.
A1  - Loparco, F.
A1  - Lott, B.
A1  - Lovellette, M. N.
A1  - Lubrano, P.
A1  - Madejski, G. M.
A1  - Makeev, A.
A1  - Max-Moerbeck, W.
A1  - Mazziotta, Mario Nicola
A1  - McEnery, J. E.
A1  - Mehault, J.
A1  - Michelson, P. F.
A1  - Mitthumsiri, W.
A1  - Mizuno, T.
A1  - Moiseev, A. A.
A1  - Monte, C.
A1  - Monzani, M. E.
A1  - Morselli, A.
A1  - Moskalenko, I. V.
A1  - Murgia, S.
A1  - Naumann-Godo, M.
A1  - Nishino, S.
A1  - Nolan, P. L.
A1  - Norris, J. P.
A1  - Nuss, E.
A1  - Ohsugi, T.
A1  - Okumura, A.
A1  - Omodei, N.
A1  - Orlando, E.
A1  - Ormes, J. F.
A1  - Paneque, D.
A1  - Panetta, J. H.
A1  - Parent, D.
A1  - Pavlidou, V.
A1  - Pearson, T. J.
A1  - Pelassa, V.
A1  - Pepe, M.
A1  - Pesce-Rollins, M.
A1  - Piron, F.
A1  - Porter, T. A.
A1  - Raino, S.
A1  - Rando, R.
A1  - Razzano, M.
A1  - Readhead, A.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Richards, J. L.
A1  - Ripken, J.
A1  - Ritz, S.
A1  - Roth, M.
A1  - Sadrozinski, H. F. -W.
A1  - Sanchez, D.
A1  - Sander, A.
A1  - Scargle, J. D.
A1  - Sgro, C.
A1  - Siskind, E. J.
A1  - Smith, P. D.
A1  - Spandre, G.
A1  - Spinelli, P.
A1  - Stawarz, L.
A1  - Stevenson, M.
A1  - Strickman, M. S.
A1  - Sokolovsky, K. V.
A1  - Suson, D. J.
A1  - Takahashi, H.
A1  - Takahashi, T.
A1  - Tanaka, T.
A1  - Thayer, J. B.
A1  - Thayer, J. G.
A1  - Thompson, D. J.
A1  - Tibaldo, L.
A1  - Torres, F.
A1  - Tosti, G.
A1  - Tramacere, A.
A1  - Uchiyama, Y.
A1  - Usher, T. L.
A1  - Vandenbroucke, J.
A1  - Vasileiou, V.
A1  - Vilchez, N.
A1  - Vitale, V.
A1  - Waite, A. P.
A1  - Wang, P.
A1  - Wehrle, A. E.
A1  - Winer, B. L.
A1  - Wood, K. S.
A1  - Yang, Z.
A1  - Ylinen, T.
A1  - Zensus, J. A.
A1  - Ziegler, M.
A1  - Aleksic, J.
A1  - Antonelli, L. A.
A1  - Antoranz, P.
A1  - Backes, Michael
A1  - Barrio, J. A.
A1  - Gonzalez, J. Becerra
A1  - Bednarek, W.
A1  - Berdyugin, A.
A1  - Berger, K.
A1  - Bernardini, E.
A1  - Biland, A.
A1  - Blanch Bigas, O.
A1  - Bock, R. K.
A1  - Boller, A.
A1  - Bonnoli, G.
A1  - Bordas, Pol
A1  - Tridon, D. Borla
A1  - Bosch-Ramon, Valentin
A1  - Bose, D.
A1  - Braun, I.
A1  - Bretz, T.
A1  - Camara, M.
A1  - Carmona, E.
A1  - Carosi, A.
A1  - Colin, P.
A1  - Colombo, E.
A1  - Contreras, J. L.
A1  - Cortina, J.
A1  - Covino, S.
A1  - Dazzi, F.
A1  - de Angelis, A.
A1  - del Pozo, E. De Cea
A1  - De Lotto, B.
A1  - De Maria, M.
A1  - De Sabata, F.
A1  - Mendez, C. Delgado
A1  - Ortega, A. Diago
A1  - Doert, M.
A1  - Dominguez, A.
A1  - Prester, Dijana Dominis
A1  - Dorner, D.
A1  - Doro, M.
A1  - Elsaesser, D.
A1  - Ferenc, D.
A1  - Fonseca, M. V.
A1  - Font, L.
A1  - Lopen, R. J. Garcia
A1  - Garczarczyk, M.
A1  - Gaug, M.
A1  - Giavitto, G.
A1  - Godinovi, N.
A1  - Hadasch, D.
A1  - Herrero, A.
A1  - Hildebrand, D.
A1  - Hoehne-Moench, D.
A1  - Hose, J.
A1  - Hrupec, D.
A1  - Jogler, T.
A1  - Klepser, S.
A1  - Kraehenbuehl, T.
A1  - Kranich, D.
A1  - Krause, J.
A1  - La Barbera, A.
A1  - Leonardo, E.
A1  - Lindfors, E.
A1  - Lombardi, S.
A1  - Lopez, M.
A1  - Lorenz, E.
A1  - Majumdar, P.
A1  - Makariev, E.
A1  - Maneva, G.
A1  - Mankuzhiyil, N.
A1  - Mannheim, K.
A1  - Maraschi, L.
A1  - Mariotti, M.
A1  - Martinez, M.
A1  - Mazin, D.
A1  - Meucci, M.
A1  - Miranda, J. M.
A1  - Mirzoyan, R.
A1  - Miyamoto, H.
A1  - Moldon, J.
A1  - Moralejo, A.
A1  - Nieto, D.
A1  - Nilsson, K.
A1  - Orito, R.
A1  - Oya, I.
A1  - Paoletti, R.
A1  - Paredes, J. M.
A1  - Partini, S.
A1  - Pasanen, M.
A1  - Pauss, F.
A1  - Pegna, R. G.
A1  - Perez-Torres, M. A.
A1  - Persic, M.
A1  - Peruzzo, J.
A1  - Pochon, J.
A1  - Moroni, P. G. Prada
A1  - Prada, F.
A1  - Prandini, E.
A1  - Puchades, N.
A1  - Puljak, I.
A1  - Reichardt, T.
A1  - Reinthal, R.
A1  - Rhode, W.
A1  - Ribo, M.
A1  - Rico, J.
A1  - Rissi, M.
A1  - Ruegamer, S.
A1  - Saggion, A.
A1  - Saito, K.
A1  - Saito, T. Y.
A1  - Salvati, M.
A1  - Sanchez-Conde, M.
A1  - Satalecka, K.
A1  - Scalzotto, V.
A1  - Scapin, V.
A1  - Schultz, C.
A1  - Schweizer, T.
A1  - Shayduk, M.
A1  - Shore, S. N.
A1  - Sierpowska-Bartosik, A.
A1  - Sillanpaa, A.
A1  - Sitarek, J.
A1  - Sobczynska, D.
A1  - Spanier, F.
A1  - Spiro, S.
A1  - Stamerra, A.
A1  - Steinke, B.
A1  - Storz, J.
A1  - Strah, N.
A1  - Struebig, J. C.
A1  - Suric, T.
A1  - Takalo, L. O.
A1  - Tavecchio, F.
A1  - Temnikov, P.
A1  - Terzic, T.
A1  - Tescaro, D.
A1  - Teshima, M.
A1  - Vankov, H.
A1  - Wagner, R. M.
A1  - Weitzel, Q.
A1  - Zabalza, V.
A1  - Zandanel, F.
A1  - Zanin, R.
A1  - Acciari, V. A.
A1  - Arlen, T.
A1  - Aune, T.
A1  - Benbow, W.
A1  - Boltuch, D.
A1  - Bradbury, S. M.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Cannon, A.
A1  - Cesarini, A.
A1  - Ciupik, L.
A1  - Cui, W.
A1  - Dickherber, R.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Finley, J. P.
A1  - Finnegan, G.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Gall, D.
A1  - Gillanders, G. H.
A1  - Godambe, S.
A1  - Grube, J.
A1  - Guenette, R.
A1  - Gyuk, G.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Huang, D.
A1  - Hui, C. M.
A1  - Humensky, T. B.
A1  - Kaaret, P.
A1  - Karlsson, N.
A1  - Kertzman, M.
A1  - Kieda, D.
A1  - Konopelko, A.
A1  - Krawczynski, H.
A1  - Krennrich, F.
A1  - Lang, M. J.
A1  - Maier, G.
A1  - McArthur, S.
A1  - McCann, A.
A1  - McCutcheon, M.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Ong, R.
A1  - Otte, N.
A1  - Pandel, D.
A1  - Perkins, J. S.
A1  - Pichel, A.
A1  - Pohl, M.
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reyes, L. C.
A1  - Reynolds, P. T.
A1  - Roache, E.
A1  - Rose, H. J.
A1  - Rovero, A. C.
A1  - Schroedter, M.
A1  - Sembroski, G. H.
A1  - Senturk, G. D.
A1  - Steele, D.
A1  - Swordy, S. P.
A1  - Tesic, G.
A1  - Theiling, M.
A1  - Thibadeau, S.
A1  - Varlotta, A.
A1  - Vincent, S.
A1  - Wakely, S. P.
A1  - Ward, J. E.
A1  - Weekes, T. C.
A1  - Weinstein, A.
A1  - Weisgarber, T.
A1  - Williams, D. A.
A1  - Wood, M.
A1  - Zitzer, B.
A1  - Villata, M.
A1  - Raiteri, C. M.
A1  - Aller, H. D.
A1  - Aller, M. F.
A1  - Arkharov, A. A.
A1  - Blinov, D. A.
A1  - Calcidese, P.
A1  - Chen, W. P.
A1  - Efimova, N. V.
A1  - Kimeridze, G.
A1  - Konstantinova, T. S.
A1  - Kopatskaya, E. N.
A1  - Koptelova, E.
A1  - Kurtanidze, O. M.
A1  - Kurtanidze, S. O.
A1  - Lahteenmaki, A.
A1  - Larionov, V. M.
A1  - Larionova, E. G.
A1  - Larionova, L. V.
A1  - Ligustri, R.
A1  - Morozova, D. A.
A1  - Nikolashvili, M. G.
A1  - Sigua, L. A.
A1  - Troitsky, I. S.
A1  - Angelakis, E.
A1  - Capalbi, M.
A1  - Carraminana, A.
A1  - Carrasco, L.
A1  - Cassaro, P.
A1  - de la Fuente, E.
A1  - Gurwell, M. A.
A1  - Kovalev, Y. Y.
A1  - Kovalev, Yu. A.
A1  - Krichbaum, T. P.
A1  - Krimm, H. A.
A1  - Leto, Paolo
A1  - Lister, M. L.
A1  - Maccaferri, G.
A1  - Moody, J. W.
A1  - Mori, Y.
A1  - Nestoras, I.
A1  - Orlati, A.
A1  - Pagani, C.
A1  - Pace, C.
A1  - Pearson, R.
A1  - Perri, M.
A1  - Piner, B. G.
A1  - Pushkarev, A. B.
A1  - Ros, E.
A1  - Sadun, A. C.
A1  - Sakamoto, T.
A1  - Tornikoski, M.
A1  - Yatsu, Y.
A1  - Zook, A.
T1  - Insights into the high-energy gamma-Ray emission of markarian 501 fromextensive multifrequency observations in the fermi era
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We report on the gamma-ray activity of the blazar Mrk 501 during the first 480 days of Fermi operation. We find that the average Large Area Telescope (LAT) gamma-ray spectrum of Mrk 501 can be well described by a single power-law function with a photon index of 1.78 +/- 0.03. While we observe relatively mild flux variations with the Fermi-LAT (within less than a factor of two), we detect remarkable spectral variability where the hardest observed spectral index within the LAT energy range is 1.52 +/- 0.14, and the softest one is 2.51 +/- 0.20. These unexpected spectral changes do not correlate with the measured flux variations above 0.3 GeV. In this paper, we also present the first results from the 4.5 month long multifrequency campaign (2009 March 15-August 1) on Mrk 501, which included the Very Long Baseline Array (VLBA), Swift, RXTE, MAGIC, and VERITAS, the F-GAMMA, GASP-WEBT, and other collaborations and instruments which provided excellent temporal and energy coverage of the source throughout the entire campaign. The extensive radio to TeV data set from this campaign provides us with the most detailed spectral energy distribution yet collected for this source during its relatively low activity. The average spectral energy distribution of Mrk 501 is well described by the standard one-zone synchrotron self-Compton (SSC) model. In the framework of this model, we find that the dominant emission region is characterized by a size less than or similar to 0.1 pc (comparable within a factor of few to the size of the partially resolved VLBA core at 15-43 GHz), and that the total jet power (similar or equal to 10(44) erg s(-1)) constitutes only a small fraction (similar to 10(-3)) of the Eddington luminosity. The energy distribution of the freshly accelerated radiating electrons required to fit the time-averaged data has a broken power-law form in the energy range 0.3 GeV-10 TeV, with spectral indices 2.2 and 2.7 below and above the break energy of 20 GeV. We argue that such a form is consistent with a scenario in which the bulk of the energy dissipation within the dominant emission zone of Mrk 501 is due to relativistic, proton-mediated shocks. We find that the ultrarelativistic electrons and mildly relativistic protons within the blazar zone, if comparable in number, are in approximate energy equipartition, with their energy dominating the jet magnetic field energy by about two orders of magnitude.
KW  - acceleration of particles
KW  - BL Lacertae objects: general
KW  - BL Lacertae objects: individual (Mrk 501)
KW  - galaxies: active
KW  - gamma rays: general
KW  - radiation mechanisms: non-thermal
Y1  - 2011
U6  - https://doi.org/10.1088/0004-637X/727/2/129
SN  - 0004-637X
VL  - 727
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Abdo, A. A.
A1  - Ackermann, Margit
A1  - Ajello, M.
A1  - Allafort, A. J.
A1  - Baldini, L.
A1  - Ballet, J.
A1  - Barbiellini, G.
A1  - Baring, M. G.
A1  - Bastieri, D.
A1  - Bellazzini, R.
A1  - Berenji, B.
A1  - Blandford, R. D.
A1  - Bloom, E. D.
A1  - Bonamente, E.
A1  - Borgland, A. W.
A1  - Bouvier, A.
A1  - Brandt, T. J.
A1  - Bregeon, Johan
A1  - Brigida, M.
A1  - Bruel, P.
A1  - Buehler, R.
A1  - Buson, S.
A1  - Caliandro, G. A.
A1  - Cameron, R. A.
A1  - Caraveo, P. A.
A1  - Casandjian, J. M.
A1  - Cecchi, C.
A1  - Chaty, S.
A1  - Chekhtman, A.
A1  - Cheung, C. C.
A1  - Chiang, J.
A1  - Cillis, A. N.
A1  - Ciprini, S.
A1  - Claus, R.
A1  - Cohen-Tanugi, J.
A1  - Conrad, Jan
A1  - Corbel, S.
A1  - Cutini, S.
A1  - de Angelis, A.
A1  - de Palma, F.
A1  - Dermer, C. D.
A1  - Digel, S. W.
A1  - do Couto e Silva, E.
A1  - Drell, P. S.
A1  - Drlica-Wagner, A.
A1  - Dubois, R.
A1  - Dumora, D.
A1  - Favuzzi, C.
A1  - Ferrara, E. C.
A1  - Fortin, P.
A1  - Frailis, M.
A1  - Fukazawa, Y.
A1  - Fukui, Y.
A1  - Funk, S.
A1  - Fusco, P.
A1  - Gargano, F.
A1  - Gasparrini, D.
A1  - Gehrels, N.
A1  - Germani, S.
A1  - Giglietto, N.
A1  - Giordano, F.
A1  - Giroletti, M.
A1  - Glanzman, T.
A1  - Godfrey, G.
A1  - Grenier, I. A.
A1  - Grondin, M. -H.
A1  - Guiriec, S.
A1  - Hadasch, D.
A1  - Hanabata, Y.
A1  - Harding, A. K.
A1  - Hayashida, M.
A1  - Hayashi, K.
A1  - Hays, E.
A1  - Horan, D.
A1  - Jackson, M. S.
A1  - Johannesson, G.
A1  - Johnson, A. S.
A1  - Kamae, T.
A1  - Katagiri, H.
A1  - Kataoka, J.
A1  - Kerr, M.
A1  - Knoedlseder, J.
A1  - Kuss, M.
A1  - Lande, J.
A1  - Latronico, L.
A1  - Lee, S. -H.
A1  - Lemoine-Goumard, M.
A1  - Longo, F.
A1  - Loparco, F.
A1  - Lovellette, M. N.
A1  - Lubrano, P.
A1  - Madejski, G. M.
A1  - Makeev, A.
A1  - Mazziotta, Mario Nicola
A1  - McEnery, J. E.
A1  - Michelson, P. F.
A1  - Mignani, R. P.
A1  - Mitthumsiri, W.
A1  - Mizuno, T.
A1  - Moiseev, A. A.
A1  - Monte, C.
A1  - Monzani, M. E.
A1  - Morselli, A.
A1  - Moskalenko, I. V.
A1  - Murgia, S.
A1  - Naumann-Godo, M.
A1  - Nolan, P. L.
A1  - Norris, J. P.
A1  - Nuss, E.
A1  - Ohsugi, T.
A1  - Okumura, A.
A1  - Orlando, E.
A1  - Ormes, J. F.
A1  - Paneque, D.
A1  - Parent, D.
A1  - Pelassa, V.
A1  - Pesce-Rollins, M.
A1  - Pierbattista, M.
A1  - Piron, F.
A1  - Pohl, Martin
A1  - Porter, T. A.
A1  - Raino, S.
A1  - Rando, R.
A1  - Razzano, M.
A1  - Reimer, O.
A1  - Reposeur, T.
A1  - Ritz, S.
A1  - Romani, R. W.
A1  - Roth, M.
A1  - Sadrozinski, H. F. -W.
A1  - Parkinson, P. M. Saz
A1  - Sgro, C.
A1  - Smith, D. A.
A1  - Smith, P. D.
A1  - Spandre, G.
A1  - Spinelli, P.
A1  - Strickman, M. S.
A1  - Tajima, H.
A1  - Takahashi, H.
A1  - Takahashi, T.
A1  - Tanaka, T.
A1  - Thayer, J. G.
A1  - Thayer, J. B.
A1  - Thompson, D. J.
A1  - Tibaldo, L.
A1  - Tibolla, O.
A1  - Torres, D. F.
A1  - Tosti, G.
A1  - Tramacere, A.
A1  - Troja, E.
A1  - Uchiyama, Y.
A1  - Vandenbroucke, J.
A1  - Vasileiou, V.
A1  - Vianello, G.
A1  - Vilchez, N.
A1  - Vitale, V.
A1  - Waite, A. P.
A1  - Wang, P.
A1  - Winer, B. L.
A1  - Wood, K. S.
A1  - Yamamoto, H.
A1  - Yamazaki, R.
A1  - Yang, Z.
A1  - Ziegler, M.
T1  - Observations of the young supernova remnant RX J1713.7-3946 with the fermi large area telescope
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We present observations of the young supernova remnant (SNR) RX J1713.7-3946 with the Fermi Large Area Telescope (LAT). We clearly detect a source positionally coincident with the SNR. The source is extended with a best-fit extension of 0 degrees.55 +/- 0 degrees.04 matching the size of the non-thermal X-ray and TeV gamma-ray emission from the remnant. The positional coincidence and the matching extended emission allow us to identify the LAT source with SNR RX J1713.7-3946. The spectrum of the source can be described by a very hard power law with a photon index of Gamma = 1.5 +/- 0.1 that coincides in normalization with the steeper H. E. S. S.-detected gamma-ray spectrum at higher energies. The broadband gamma-ray emission is consistent with a leptonic origin as the dominant mechanism for the gamma-ray emission.
KW  - acceleration of particles
KW  - gamma rays: general
KW  - gamma rays: ISM
KW  - ISM: individual objects (RX J1713.7-3946)
KW  - ISM: supernova remnants
KW  - radiation mechanisms: non-thermal
Y1  - 2011
U6  - https://doi.org/10.1088/0004-637X/734/1/28
SN  - 0004-637X
VL  - 734
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - De Angelis, A.
A1  - Tatischeff, V.
A1  - Grenier, I. A.
A1  - McEnery, J.
A1  - Mallamaci, Manuela
A1  - Tavani, M.
A1  - Oberlack, U.
A1  - Hanlon, L.
A1  - Walter, R.
A1  - Argan, A.
A1  - Von Ballmoos, P.
A1  - Bulgarelli, A.
A1  - Bykov, A.
A1  - Hernanz, M.
A1  - Kanbach, G.
A1  - Kuvvetli, I.
A1  - Pearce, M.
A1  - Zdziarski, A.
A1  - Conrad, J.
A1  - Ghisellini, G.
A1  - Harding, A.
A1  - Isern, J.
A1  - Leising, M.
A1  - Longo, F.
A1  - Madejski, G.
A1  - Martinez, M.
A1  - Mazziotta, Mario Nicola
A1  - Paredes, J. M.
A1  - Pohl, Martin
A1  - Rando, R.
A1  - Razzano, M.
A1  - Aboudan, A.
A1  - Ackermann, M.
A1  - Addazi, A.
A1  - Ajello, M.
A1  - Albertus, C.
A1  - Alvarez, J. M.
A1  - Ambrosi, G.
A1  - Anton, S.
A1  - Antonelli, L. A.
A1  - Babic, A.
A1  - Baibussinov, B.
A1  - Balbom, M.
A1  - Baldini, L.
A1  - Balman, S.
A1  - Bambi, C.
A1  - Barres de Almeida, U.
A1  - Barrio, J. A.
A1  - Bartels, R.
A1  - Bastieri, D.
A1  - Bednarek, W.
A1  - Bernard, D.
A1  - Bernardini, E.
A1  - Bernasconi, T.
A1  - Bertucci, B.
A1  - Biland, A.
A1  - Bissaldi, E.
A1  - Boettcher, M.
A1  - Bonvicini, V.
A1  - Bosch-Ramon, V.
A1  - Bottacini, E.
A1  - Bozhilov, V.
A1  - Bretz, T.
A1  - Branchesi, M.
A1  - Brdar, V.
A1  - Bringmann, T.
A1  - Brogna, A.
A1  - Jorgensen, C. Budtz
A1  - Busetto, G.
A1  - Buson, S.
A1  - Busso, M.
A1  - Caccianiga, A.
A1  - Camera, S.
A1  - Campana, R.
A1  - Caraveo, P.
A1  - Cardillo, M.
A1  - Carlson, P.
A1  - Celestin, S.
A1  - Cermeno, M.
A1  - Chen, A.
A1  - Cheung, C. C.
A1  - Churazov, E.
A1  - Ciprini, S.
A1  - Coc, A.
A1  - Colafrancesco, S.
A1  - Coleiro, A.
A1  - Collmar, W.
A1  - Coppi, P.
A1  - Curado da Silva, R.
A1  - Cutini, S.
A1  - De Lotto, B.
A1  - de Martino, D.
A1  - De Rosa, A.
A1  - Del Santo, M.
A1  - Delgado, L.
A1  - Diehl, R.
A1  - Dietrich, S.
A1  - Dolgov, A. D.
A1  - Dominguez, A.
A1  - Prester, D. Dominis
A1  - Donnarumma, I.
A1  - Dorner, D.
A1  - Doro, M.
A1  - Dutra, M.
A1  - Elsaesser, D.
A1  - Fabrizio, M.
A1  - Fernandez-Barral, A.
A1  - Fioretti, V.
A1  - Foffano, L.
A1  - Formato, V.
A1  - Fornengo, N.
A1  - Foschini, L.
A1  - Franceschini, A.
A1  - Franckowiak, A.
A1  - Funk, S.
A1  - Fuschino, F.
A1  - Gaggero, D.
A1  - Galanti, G.
A1  - Gargano, F.
A1  - Gasparrini, D.
A1  - Gehrz, R.
A1  - Giammaria, P.
A1  - Giglietto, N.
A1  - Giommi, P.
A1  - Giordano, F.
A1  - Giroletti, M.
A1  - Ghirlanda, G.
A1  - Godinovic, N.
A1  - Gouiffes, C.
A1  - Grove, J. E.
A1  - Hamadache, C.
A1  - Hartmann, D. H.
A1  - Hayashida, M.
A1  - Hryczuk, A.
A1  - Jean, P.
A1  - Johnson, T.
A1  - Jose, J.
A1  - Kaufmann, S.
A1  - Khelifi, B.
A1  - Kiener, J.
A1  - Knodlseder, J.
A1  - Kolem, M.
A1  - Kopp, J.
A1  - Kozhuharov, V.
A1  - Labanti, C.
A1  - Lalkovski, S.
A1  - Laurent, P.
A1  - Limousin, O.
A1  - Linares, M.
A1  - Lindfors, E.
A1  - Lindner, M.
A1  - Liu, J.
A1  - Lombardi, S.
A1  - Loparco, F.
A1  - Lopez-Coto, R.
A1  - Lopez Moya, M.
A1  - Lott, B.
A1  - Lubrano, P.
A1  - Malyshev, D.
A1  - Mankuzhiyil, N.
A1  - Mannheim, K.
A1  - Marcha, M. J.
A1  - Marciano, A.
A1  - Marcote, B.
A1  - Mariotti, M.
A1  - Marisaldi, M.
A1  - McBreen, S.
A1  - Mereghetti, S.
A1  - Merle, A.
A1  - Mignani, R.
A1  - Minervini, G.
A1  - Moiseev, A.
A1  - Morselli, A.
A1  - Moura, F.
A1  - Nakazawa, K.
A1  - Nava, L.
A1  - Nieto, D.
A1  - Orienti, M.
A1  - Orio, M.
A1  - Orlando, E.
A1  - Orleanski, P.
A1  - Paiano, S.
A1  - Paoletti, R.
A1  - Papitto, A.
A1  - Pasquato, M.
A1  - Patricelli, B.
A1  - Perez-Garcia, M. A.
A1  - Persic, M.
A1  - Piano, G.
A1  - Pichel, A.
A1  - Pimenta, M.
A1  - Pittori, C.
A1  - Porter, T.
A1  - Poutanen, J.
A1  - Prandini, E.
A1  - Prantzos, N.
A1  - Produit, N.
A1  - Profumo, S.
A1  - Queiroz, F. S.
A1  - Raino, S.
A1  - Raklev, A.
A1  - Regis, M.
A1  - Reichardt, I.
A1  - Rephaeli, Y.
A1  - Rico, J.
A1  - Rodejohann, W.
A1  - Fernandez, G. Rodriguez
A1  - Roncadelli, M.
A1  - Roso, L.
A1  - Rovero, A.
A1  - Ruffini, R.
A1  - Sala, G.
A1  - Sanchez-Conde, M. A.
A1  - Santangelo, Andrea
A1  - Parkinson, P. Saz
A1  - Sbarrato, T.
A1  - Shearer, A.
A1  - Shellard, R.
A1  - Short, K.
A1  - Siegert, T.
A1  - Siqueira, C.
A1  - Spinelli, P.
A1  - Stamerra, A.
A1  - Starrfield, S.
A1  - Strong, A.
A1  - Strumke, I.
A1  - Tavecchio, F.
A1  - Taverna, R.
A1  - Terzic, T.
A1  - Thompson, D. J.
A1  - Tibolla, O.
A1  - Torres, D. F.
A1  - Turolla, R.
A1  - Ulyanov, A.
A1  - Ursi, A.
A1  - Vacchi, A.
A1  - Van den Abeele, J.
A1  - Vankova-Kirilovai, G.
A1  - Venter, C.
A1  - Verrecchia, F.
A1  - Vincent, P.
A1  - Wang, X.
A1  - Weniger, C.
A1  - Wu, X.
A1  - Zaharijas, G.
A1  - Zampieri, L.
A1  - Zane, S.
A1  - Zimmer, S.
A1  - Zoglauer, A.
T1  - Science with e-ASTROGAM A space mission for MeV-GeV gamma-ray astrophysics
JF  - Journal of High Energy Astrophysics
Y1  - 2018
U6  - https://doi.org/10.1016/j.jheap.2018.07.001
SN  - 2214-4048
SN  - 2214-4056
VL  - 19
SP  - 1
EP  - 106
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Ackermann, Margit
A1  - Ajello, M.
A1  - Allafort, A. J.
A1  - Baldini, L.
A1  - Ballet, J.
A1  - Barbiellini, G.
A1  - Bastieri, D.
A1  - Belfiore, A.
A1  - Bellazzini, R.
A1  - Berenji, B.
A1  - Blandford, R. D.
A1  - Bloom, E. D.
A1  - Bonamente, E.
A1  - Borgland, A. W.
A1  - Bottacini, E.
A1  - Brigida, M.
A1  - Bruel, P.
A1  - Buehler, R.
A1  - Buson, S.
A1  - Caliandro, G. A.
A1  - Cameron, R. A.
A1  - Caraveo, P. A.
A1  - Casandjian, J. M.
A1  - Cecchi, C.
A1  - Chekhtman, A.
A1  - Cheung, C. C.
A1  - Chiang, J.
A1  - Ciprini, S.
A1  - Claus, R.
A1  - Cohen-Tanugi, J.
A1  - de Angelis, A.
A1  - de Palma, F.
A1  - Dermer, C. D.
A1  - do Couto e Silva, E.
A1  - Drell, P. S.
A1  - Dumora, D.
A1  - Favuzzi, C.
A1  - Fegan, S. J.
A1  - Focke, W. B.
A1  - Fortin, P.
A1  - Fukazawa, Y.
A1  - Fusco, P.
A1  - Gargano, F.
A1  - Germani, S.
A1  - Giglietto, N.
A1  - Giordano, F.
A1  - Giroletti, M.
A1  - Glanzman, T.
A1  - Godfrey, G.
A1  - Grenier, I. A.
A1  - Guillemot, L.
A1  - Guiriec, S.
A1  - Hadasch, D.
A1  - Hanabata, Y.
A1  - Harding, A. K.
A1  - Hayashida, M.
A1  - Hayashi, K.
A1  - Hays, E.
A1  - Johannesson, G.
A1  - Johnson, A. S.
A1  - Kamae, T.
A1  - Katagiri, H.
A1  - Kataoka, J.
A1  - Kerr, M.
A1  - Knoedlseder, J.
A1  - Kuss, M.
A1  - Lande, J.
A1  - Latronico, L.
A1  - Lee, S. -H.
A1  - Longo, F.
A1  - Loparco, F.
A1  - Lott, B.
A1  - Lovellette, M. N.
A1  - Lubrano, P.
A1  - Martin, P.
A1  - Mazziotta, Mario Nicola
A1  - McEnery, J. E.
A1  - Mehault, J.
A1  - Michelson, P. F.
A1  - Mitthumsiri, W.
A1  - Mizuno, T.
A1  - Monte, C.
A1  - Monzani, M. E.
A1  - Morselli, A.
A1  - Moskalenko, I. V.
A1  - Murgia, S.
A1  - Naumann-Godo, M.
A1  - Nolan, P. L.
A1  - Norris, J. P.
A1  - Nuss, E.
A1  - Ohsugi, T.
A1  - Okumura, A.
A1  - Orlando, E.
A1  - Ormes, J. F.
A1  - Ozaki, M.
A1  - Paneque, D.
A1  - Parent, D.
A1  - Pesce-Rollins, M.
A1  - Pierbattista, M.
A1  - Piron, F.
A1  - Pohl, Martin
A1  - Prokhorov, D.
A1  - Raino, S.
A1  - Rando, R.
A1  - Razzano, M.
A1  - Reposeur, T.
A1  - Ritz, S.
A1  - Parkinson, P. M. Saz
A1  - Sgro, C.
A1  - Siskind, E. J.
A1  - Smith, P. D.
A1  - Spinelli, P.
A1  - Strong, A. W.
A1  - Takahashi, H.
A1  - Tanaka, T.
A1  - Thayer, J. G.
A1  - Thayer, J. B.
A1  - Thompson, D. J.
A1  - Tibaldo, L.
A1  - Torres, D. F.
A1  - Tosti, G.
A1  - Tramacere, A.
A1  - Troja, E.
A1  - Uchiyama, Y.
A1  - Vandenbroucke, J.
A1  - Vasileiou, V.
A1  - Vianello, G.
A1  - Vitale, V.
A1  - Waite, A. P.
A1  - Wang, P.
A1  - Winer, B. L.
A1  - Wood, K. S.
A1  - Yang, Z.
A1  - Zimmer, S.
A1  - Bontemps, S.
T1  - A cocoon of freshly accelerated cosmic rays detected by fermi in the cygnus superbubble
JF  - Science
N2  - The origin of Galactic cosmic rays is a century-long puzzle. Indirect evidence points to their acceleration by supernova shockwaves, but we know little of their escape from the shock and their evolution through the turbulent medium surrounding massive stars. Gamma rays can probe their spreading through the ambient gas and radiation fields. The Fermi Large Area Telescope (LAT) has observed the star-forming region of Cygnus X. The 1- to 100-gigaelectronvolt images reveal a 50-parsec-wide cocoon of freshly accelerated cosmic rays that flood the cavities carved by the stellar winds and ionization fronts from young stellar clusters. It provides an example to study the youth of cosmic rays in a superbubble environment before they merge into the older Galactic population.
Y1  - 2011
U6  - https://doi.org/10.1126/science.1210311
SN  - 0036-8075
VL  - 334
IS  - 6059
SP  - 1103
EP  - 1107
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  - 
TY  - JOUR
A1  - Warrington, Nicole
A1  - Beaumont, Robin
A1  - Horikoshi, Momoko
A1  - Day, Felix R.
A1  - Helgeland, Øyvind
A1  - Laurin, Charles
A1  - Bacelis, Jonas
A1  - Peng, Shouneng
A1  - Hao, Ke
A1  - Feenstra, Bjarke
A1  - Wood, Andrew R.
A1  - Mahajan, Anubha
A1  - Tyrrell, Jessica
A1  - Robertson, Neil R.
A1  - Rayner, N. William
A1  - Qiao, Zhen
A1  - Moen, Gunn-Helen
A1  - Vaudel, Marc
A1  - Marsit, Carmen
A1  - Chen, Jia
A1  - Nodzenski, Michael
A1  - Schnurr, Theresia M.
A1  - Zafarmand, Mohammad Hadi
A1  - Bradfield, Jonathan P.
A1  - Grarup, Niels
A1  - Kooijman, Marjolein N.
A1  - Li-Gao, Ruifang
A1  - Geller, Frank
A1  - Ahluwalia, Tarunveer Singh
A1  - Paternoster, Lavinia
A1  - Rueedi, Rico
A1  - Huikari, Ville
A1  - Hottenga, Jouke-Jan
A1  - Lyytikäinen, Leo-Pekka
A1  - Cavadino, Alana
A1  - Metrustry, Sarah
A1  - Cousminer, Diana L.
A1  - Wu, Ying
A1  - Thiering, Elisabeth Paula
A1  - Wang, Carol A.
A1  - Have, Christian Theil
A1  - Vilor-Tejedor, Natalia
A1  - Joshi, Peter K.
A1  - Painter, Jodie N.
A1  - Ntalla, Ioanna
A1  - Myhre, Ronny
A1  - Pitkänen, Niina
A1  - van Leeuwen, Elisabeth M.
A1  - Joro, Raimo
A1  - Lagou, Vasiliki
A1  - Richmond, Rebecca C.
A1  - Espinosa, Ana
A1  - Barton, Sheila J.
A1  - Inskip, Hazel M.
A1  - Holloway, John W.
A1  - Santa-Marina, Loreto
A1  - Estivill, Xavier
A1  - Ang, Wei
A1  - Marsh, Julie A.
A1  - Reichetzeder, Christoph
A1  - Marullo, Letizia
A1  - Hocher, Berthold
A1  - Lunetta, Kathryn L.
A1  - Murabito, Joanne M.
A1  - Relton, Caroline L.
A1  - Kogevinas, Manolis
A1  - Chatzi, Leda
A1  - Allard, Catherine
A1  - Bouchard, Luigi
A1  - Hivert, Marie-France
A1  - Zhang, Ge
A1  - Muglia, Louis J.
A1  - Heikkinen, Jani
A1  - Morgen, Camilla S.
A1  - van Kampen, Antoine H. C.
A1  - van Schaik, Barbera D. C.
A1  - Mentch, Frank D.
A1  - Langenberg, Claudia
A1  - Scott, Robert A.
A1  - Zhao, Jing Hua
A1  - Hemani, Gibran
A1  - Ring, Susan M.
A1  - Bennett, Amanda J.
A1  - Gaulton, Kyle J.
A1  - Fernandez-Tajes, Juan
A1  - van Zuydam, Natalie R.
A1  - Medina-Gomez, Carolina
A1  - de Haan, Hugoline G.
A1  - Rosendaal, Frits R.
A1  - Kutalik, Zoltán
A1  - Marques-Vidal, Pedro
A1  - Das, Shikta
A1  - Willemsen, Gonneke
A1  - Mbarek, Hamdi
A1  - Müller-Nurasyid, Martina
A1  - Standl, Marie
A1  - Appel, Emil V. R.
A1  - Fonvig, Cilius Esmann
A1  - Trier, Caecilie
A1  - van Beijsterveldt, Catharina E. M.
A1  - Murcia, Mario
A1  - Bustamante, Mariona
A1  - Bonàs-Guarch, Sílvia
A1  - Hougaard, David M.
A1  - Mercader, Josep M.
A1  - Linneberg, Allan
A1  - Schraut, Katharina E.
A1  - Lind, Penelope A.
A1  - Medland, Sarah Elizabeth
A1  - Shields, Beverley M.
A1  - Knight, Bridget A.
A1  - Chai, Jin-Fang
A1  - Panoutsopoulou, Kalliope
A1  - Bartels, Meike
A1  - Sánchez, Friman
A1  - Stokholm, Jakob
A1  - Torrents, David
A1  - Vinding, Rebecca K.
A1  - Willems, Sara M.
A1  - Atalay, Mustafa
A1  - Chawes, Bo L.
A1  - Kovacs, Peter
A1  - Prokopenko, Inga
A1  - Tuke, Marcus A.
A1  - Yaghootkar, Hanieh
A1  - Ruth, Katherine S.
A1  - Jones, Samuel E.
A1  - Loh, Po-Ru
A1  - Murray, Anna
A1  - Weedon, Michael N.
A1  - Tönjes, Anke
A1  - Stumvoll, Michael
A1  - Michaelsen, Kim Fleischer
A1  - Eloranta, Aino-Maija
A1  - Lakka, Timo A.
A1  - van Duijn, Cornelia M.
A1  - Kiess, Wieland
A1  - Koerner, Antje
A1  - Niinikoski, Harri
A1  - Pahkala, Katja
A1  - Raitakari, Olli T.
A1  - Jacobsson, Bo
A1  - Zeggini, Eleftheria
A1  - Dedoussis, George V.
A1  - Teo, Yik-Ying
A1  - Saw, Seang-Mei
A1  - Montgomery, Grant W.
A1  - Campbell, Harry
A1  - Wilson, James F.
A1  - Vrijkotte, Tanja G. M.
A1  - Vrijheid, Martine
A1  - de Geus, Eco J. C. N.
A1  - Hayes, M. Geoffrey
A1  - Kadarmideen, Haja N.
A1  - Holm, Jens-Christian
A1  - Beilin, Lawrence J.
A1  - Pennell, Craig E.
A1  - Heinrich, Joachim
A1  - Adair, Linda S.
A1  - Borja, Judith B.
A1  - Mohlke, Karen L.
A1  - Eriksson, Johan G.
A1  - Widen, Elisabeth E.
A1  - Hattersley, Andrew T.
A1  - Spector, Tim D.
A1  - Kaehoenen, Mika
A1  - Viikari, Jorma S.
A1  - Lehtimaeki, Terho
A1  - Boomsma, Dorret I.
A1  - Sebert, Sylvain
A1  - Vollenweider, Peter
A1  - Sorensen, Thorkild I. A.
A1  - Bisgaard, Hans
A1  - Bonnelykke, Klaus
A1  - Murray, Jeffrey C.
A1  - Melbye, Mads
A1  - Nohr, Ellen A.
A1  - Mook-Kanamori, Dennis O.
A1  - Rivadeneira, Fernando
A1  - Hofman, Albert
A1  - Felix, Janine F.
A1  - Jaddoe, Vincent W. V.
A1  - Hansen, Torben
A1  - Pisinger, Charlotta
A1  - Vaag, Allan A.
A1  - Pedersen, Oluf
A1  - Uitterlinden, Andre G.
A1  - Jarvelin, Marjo-Riitta
A1  - Power, Christine
A1  - Hypponen, Elina
A1  - Scholtens, Denise M.
A1  - Lowe, William L.
A1  - Smith, George Davey
A1  - Timpson, Nicholas J.
A1  - Morris, Andrew P.
A1  - Wareham, Nicholas J.
A1  - Hakonarson, Hakon
A1  - Grant, Struan F. A.
A1  - Frayling, Timothy M.
A1  - Lawlor, Debbie A.
A1  - Njolstad, Pal R.
A1  - Johansson, Stefan
A1  - Ong, Ken K.
A1  - McCarthy, Mark I.
A1  - Perry, John R. B.
A1  - Evans, David M.
A1  - Freathy, Rachel M.
T1  - Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
JF  - Nature genetics
N2  - Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). We used structural equation modeling to decompose the contributions of direct fetal and indirect maternal genetic effects, then applied Mendelian randomization to illuminate causal pathways. For example, both indirect maternal and direct fetal genetic effects drive the observational relationship between lower birth weight and higher later blood pressure: maternal blood pressure-raising alleles reduce offspring birth weight, but only direct fetal effects of these alleles, once inherited, increase later offspring blood pressure. Using maternal birth weight-lowering genotypes to proxy for an adverse intrauterine environment provided no evidence that it causally raises offspring blood pressure, indicating that the inverse birth weight-blood pressure association is attributable to genetic effects, and not to intrauterine programming.
Y1  - 2019
SN  - 1061-4036
SN  - 1546-1718
VL  - 51
IS  - 5
SP  - 804
EP  - +
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - JOUR
A1  - Middeldorp, Christel M.
A1  - Mahajan, Anubha
A1  - Horikoshi, Momoko
A1  - Robertson, Neil R.
A1  - Beaumont, Robin N.
A1  - Bradfield, Jonathan P.
A1  - Bustamante, Mariona
A1  - Cousminer, Diana L.
A1  - Day, Felix R.
A1  - De Silva, N. Maneka
A1  - Guxens, Monica
A1  - Mook-Kanamori, Dennis O.
A1  - St Pourcain, Beate
A1  - Warrington, Nicole M.
A1  - Adair, Linda S.
A1  - Ahlqvist, Emma
A1  - Ahluwalia, Tarunveer Singh
A1  - Almgren, Peter
A1  - Ang, Wei
A1  - Atalay, Mustafa
A1  - Auvinen, Juha
A1  - Bartels, Meike
A1  - Beckmann, Jacques S.
A1  - Bilbao, Jose Ramon
A1  - Bond, Tom
A1  - Borja, Judith B.
A1  - Cavadino, Alana
A1  - Charoen, Pimphen
A1  - Chen, Zhanghua
A1  - Coin, Lachlan
A1  - Cooper, Cyrus
A1  - Curtin, John A.
A1  - Custovic, Adnan
A1  - Das, Shikta
A1  - Davies, Gareth E.
A1  - Dedoussis, George V.
A1  - Duijts, Liesbeth
A1  - Eastwood, Peter R.
A1  - Eliasen, Anders U.
A1  - Elliott, Paul
A1  - Eriksson, Johan G.
A1  - Estivill, Xavier
A1  - Fadista, Joao
A1  - Fedko, Iryna O.
A1  - Frayling, Timothy M.
A1  - Gaillard, Romy
A1  - Gauderman, W. James
A1  - Geller, Frank
A1  - Gilliland, Frank
A1  - Gilsanz, Vincente
A1  - Granell, Raquel
A1  - Grarup, Niels
A1  - Groop, Leif
A1  - Hadley, Dexter
A1  - Hakonarson, Hakon
A1  - Hansen, Torben
A1  - Hartman, Catharina A.
A1  - Hattersley, Andrew T.
A1  - Hayes, M. Geoffrey
A1  - Hebebrand, Johannes
A1  - Heinrich, Joachim
A1  - Helgeland, Oyvind
A1  - Henders, Anjali K.
A1  - Henderson, John
A1  - Henriksen, Tine B.
A1  - Hirschhorn, Joel N.
A1  - Hivert, Marie-France
A1  - Hocher, Berthold
A1  - Holloway, John W.
A1  - Holt, Patrick
A1  - Hottenga, Jouke-Jan
A1  - Hypponen, Elina
A1  - Iniguez, Carmen
A1  - Johansson, Stefan
A1  - Jugessur, Astanand
A1  - Kahonen, Mika
A1  - Kalkwarf, Heidi J.
A1  - Kaprio, Jaakko
A1  - Karhunen, Ville
A1  - Kemp, John P.
A1  - Kerkhof, Marjan
A1  - Koppelman, Gerard H.
A1  - Korner, Antje
A1  - Kotecha, Sailesh
A1  - Kreiner-Moller, Eskil
A1  - Kulohoma, Benard
A1  - Kumar, Ashish
A1  - Kutalik, Zoltan
A1  - Lahti, Jari
A1  - Lappe, Joan M.
A1  - Larsson, Henrik
A1  - Lehtimaki, Terho
A1  - Lewin, Alexandra M.
A1  - Li, Jin
A1  - Lichtenstein, Paul
A1  - Lindgren, Cecilia M.
A1  - Lindi, Virpi
A1  - Linneberg, Allan
A1  - Liu, Xueping
A1  - Liu, Jun
A1  - Lowe, William L.
A1  - Lundstrom, Sebastian
A1  - Lyytikainen, Leo-Pekka
A1  - Ma, Ronald C. W.
A1  - Mace, Aurelien
A1  - Magi, Reedik
A1  - Magnus, Per
A1  - Mamun, Abdullah A.
A1  - Mannikko, Minna
A1  - Martin, Nicholas G.
A1  - Mbarek, Hamdi
A1  - McCarthy, Nina S.
A1  - Medland, Sarah E.
A1  - Melbye, Mads
A1  - Melen, Erik
A1  - Mohlke, Karen L.
A1  - Monnereau, Claire
A1  - Morgen, Camilla S.
A1  - Morris, Andrew P.
A1  - Murray, Jeffrey C.
A1  - Myhre, Ronny
A1  - Najman, Jackob M.
A1  - Nivard, Michel G.
A1  - Nohr, Ellen A.
A1  - Nolte, Ilja M.
A1  - Ntalla, Ioanna
A1  - Oberfield, Sharon E.
A1  - Oken, Emily
A1  - Oldehinkel, Albertine J.
A1  - Pahkala, Katja
A1  - Palviainen, Teemu
A1  - Panoutsopoulou, Kalliope
A1  - Pedersen, Oluf
A1  - Pennell, Craig E.
A1  - Pershagen, Goran
A1  - Pitkanen, Niina
A1  - Plomin, Robert
A1  - Power, Christine
A1  - Prasad, Rashmi B.
A1  - Prokopenko, Inga
A1  - Pulkkinen, Lea
A1  - Raikkonen, Katri
A1  - Raitakari, Olli T.
A1  - Reynolds, Rebecca M.
A1  - Richmond, Rebecca C.
A1  - Rivadeneira, Fernando
A1  - Rodriguez, Alina
A1  - Rose, Richard J.
A1  - Salem, Rany
A1  - Santa-Marina, Loreto
A1  - Saw, Seang-Mei
A1  - Schnurr, Theresia M.
A1  - Scott, James G.
A1  - Selzam, Saskia
A1  - Shepherd, John A.
A1  - Simpson, Angela
A1  - Skotte, Line
A1  - Sleiman, Patrick M. A.
A1  - Snieder, Harold
A1  - Sorensen, Thorkild I. A.
A1  - Standl, Marie
A1  - Steegers, Eric A. P.
A1  - Strachan, David P.
A1  - Straker, Leon
A1  - Strandberg, Timo
A1  - Taylor, Michelle
A1  - Teo, Yik-Ying
A1  - Thiering, Elisabeth
A1  - Torrent, Maties
A1  - Tyrrell, Jessica
A1  - Uitterlinden, Andre G.
A1  - van Beijsterveldt, Toos
A1  - van der Most, Peter J.
A1  - van Duijn, Cornelia M.
A1  - Viikari, Jorma
A1  - Vilor-Tejedor, Natalia
A1  - Vogelezang, Suzanne
A1  - Vonk, Judith M.
A1  - Vrijkotte, Tanja G. M.
A1  - Vuoksimaa, Eero
A1  - Wang, Carol A.
A1  - Watkins, William J.
A1  - Wichmann, H-Erich
A1  - Willemsen, Gonneke
A1  - Williams, Gail M.
A1  - Wilson, James F.
A1  - Wray, Naomi R.
A1  - Xu, Shujing
A1  - Xu, Cheng-Jian
A1  - Yaghootkar, Hanieh
A1  - Yi, Lu
A1  - Zafarmand, Mohammad Hadi
A1  - Zeggini, Eleftheria
A1  - Zemel, Babette S.
A1  - Hinney, Anke
A1  - Lakka, Timo A.
A1  - Whitehouse, Andrew J. O.
A1  - Sunyer, Jordi
A1  - Widen, Elisabeth E.
A1  - Feenstra, Bjarke
A1  - Sebert, Sylvain
A1  - Jacobsson, Bo
A1  - Njolstad, Pal R.
A1  - Stoltenberg, Camilla
A1  - Smith, George Davey
A1  - Lawlor, Debbie A.
A1  - Paternoster, Lavinia
A1  - Timpson, Nicholas J.
A1  - Ong, Ken K.
A1  - Bisgaard, Hans
A1  - Bonnelykke, Klaus
A1  - Jaddoe, Vincent W. V.
A1  - Tiemeier, Henning
A1  - Jarvelin, Marjo-Riitta
A1  - Evans, David M.
A1  - Perry, John R. B.
A1  - Grant, Struan F. A.
A1  - Boomsma, Dorret I.
A1  - Freathy, Rachel M.
A1  - McCarthy, Mark I.
A1  - Felix, Janine F.
T1  - The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia
BT  - design, results and future prospects
JF  - European journal of epidemiology
N2  - The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.
KW  - Genetics
KW  - Consortium
KW  - Childhood traits and disorders
KW  - Longitudinal
Y1  - 2019
U6  - https://doi.org/10.1007/s10654-019-00502-9
SN  - 0393-2990
SN  - 1573-7284
VL  - 34
IS  - 3
SP  - 279
EP  - 300
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Le Friant, A.
A1  - Ishizuka, O.
A1  - Boudon, G.
A1  - Palmer, M. R.
A1  - Talling, P. J.
A1  - Villemant, B.
A1  - Adachi, T.
A1  - Aljahdali, M.
A1  - Breitkreuz, C.
A1  - Brunet, M.
A1  - Caron, B.
A1  - Coussens, M.
A1  - Deplus, C.
A1  - Endo, D.
A1  - Feuillet, N.
A1  - Fraas, A. J.
A1  - Fujinawa, A.
A1  - Hart, M. B.
A1  - Hatfield, R. G.
A1  - Hornbach, M.
A1  - Jutzeler, M.
A1  - Kataoka, K. S.
A1  - Komorowski, J. -C.
A1  - Lebas, E.
A1  - Lafuerza, S.
A1  - Maeno, F.
A1  - Manga, M.
A1  - Martinez-Colon, M.
A1  - McCanta, M.
A1  - Morgan, S.
A1  - Saito, T.
A1  - Slagle, A.
A1  - Sparks, S.
A1  - Stinton, A.
A1  - Stroncik, Nicole
A1  - Subramanyam, K. S. V.
A1  - Tamura, Yui
A1  - Trofimovs, J.
A1  - Voight, B.
A1  - Wall-Palmer, D.
A1  - Wang, F.
A1  - Watt, S. F. L.
T1  - Submarine record of volcanic island construction and collapse in the Lesser Antilles arc: First scientific drilling of submarine volcanic island landslides by IODP Expedition 340
JF  - Geochemistry, geophysics, geosystems
N2  - IODP Expedition 340 successfully drilled a series of sites offshore Montserrat, Martinique and Dominica in the Lesser Antilles from March to April 2012. These are among the few drill sites gathered around volcanic islands, and the first scientific drilling of large and likely tsunamigenic volcanic island-arc landslide deposits. These cores provide evidence and tests of previous hypotheses for the composition and origin of those deposits. Sites U1394, U1399, and U1400 that penetrated landslide deposits recovered exclusively seafloor sediment, comprising mainly turbidites and hemipelagic deposits, and lacked debris avalanche deposits. This supports the concepts that i/ volcanic debris avalanches tend to stop at the slope break, and ii/ widespread and voluminous failures of preexisting low-gradient seafloor sediment can be triggered by initial emplacement of material from the volcano. Offshore Martinique (U1399 and 1400), the landslide deposits comprised blocks of parallel strata that were tilted or microfaulted, sometimes separated by intervals of homogenized sediment (intense shearing), while Site U1394 offshore Montserrat penetrated a flat-lying block of intact strata. The most likely mechanism for generating these large-scale seafloor sediment failures appears to be propagation of a decollement from proximal areas loaded and incised by a volcanic debris avalanche. These results have implications for the magnitude of tsunami generation. Under some conditions, volcanic island landslide deposits composed of mainly seafloor sediment will tend to form smaller magnitude tsunamis than equivalent volumes of subaerial block-rich mass flows rapidly entering water. Expedition 340 also successfully drilled sites to access the undisturbed record of eruption fallout layers intercalated with marine sediment which provide an outstanding high-resolution data set to analyze eruption and landslides cycles, improve understanding of magmatic evolution as well as offshore sedimentation processes.
KW  - landslide
KW  - volcanic island
KW  - debris avalanche
KW  - seafloor sediment failure
KW  - tsunami
KW  - IODP
Y1  - 2015
U6  - https://doi.org/10.1002/2014GC005652
SN  - 1525-2027
VL  - 16
IS  - 2
SP  - 420
EP  - 442
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Townsley, Leisa K.
A1  - Broos, Patrick S.
A1  - Corcoran, Michael F.
A1  - Feigelson, Eric D.
A1  - Gagne, Marc
A1  - Montmerle, Thierry
A1  - Oey, M. S.
A1  - Smith, Nathan
A1  - Garmire, Gordon P.
A1  - Getman, Konstantin V.
A1  - Povich, Matthew S.
A1  - Evans, Nancy Remage
A1  - Naze, Yael
A1  - Parkin, E. R.
A1  - Preibisch, Thomas
A1  - Wang, Junfeng
A1  - Wou, Scott J.
A1  - Chu, You-Hua
A1  - Cohen, David H.
A1  - Gruendl, Robert A.
A1  - Hamaguchi, Kenji
A1  - King, Robert R.
A1  - Mac Low, Mordecai-Mark
A1  - McCaughrean, Mark J.
A1  - Moffat, Anthony F. J.
A1  - Oskinova, Lida
A1  - Pittard, Julian M.
A1  - Stassun, Keivan G.
A1  - Ud-Doula, Asif
A1  - Walborn, Nolan R.
A1  - Waldron, Wayne L.
A1  - Churchwell, Ed
A1  - Nictiols, J. S.
A1  - Owocki, Stanley P.
A1  - Schulz, Norbert S.
T1  - An introduction to the chandra carina complex project
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Supplement series
N2  - The Great Nebula in Carina provides an exceptional view into the violent massive star formation and feedback that typifies giant H II regions and starburst galaxies. We have mapped the Carina star-forming complex in X-rays, using archival Chandra data and a mosaic of 20 new 60 ks pointings using the Chandra X-ray Observatory's Advanced CCD Imaging Spectrometer, as a testbed for understanding recent and ongoing star formation and to probe Carina's regions of bright diffuse X-ray emission. This study has yielded a catalog of properties of > 14,000 X-ray point sources;> 9800 of them have multiwavelength counterparts. Using Chandra's unsurpassed X-ray spatial resolution, we have separated these point sources from the extensive, spatially-complex diffuse emission that pervades the region; X-ray properties of this diffuse emission suggest that it traces feedback from Carina's massive stars. In this introductory paper, we motivate the survey design, describe the Chandra observations, and present some simple results, providing a foundation for the 15 papers that follow in this special issue and that present detailed catalogs, methods, and science results.
KW  - H II regions
KW  - stars: massive
KW  - stars: pre-main sequence
KW  - X-rays: individual (Carina)
KW  - X-rays: ISM
KW  - X-rays: stars
Y1  - 2011
U6  - https://doi.org/10.1088/0067-0049/194/1/1
SN  - 0067-0049
VL  - 194
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Tilmann, F.
A1  - Zhang, Y.
A1  - Moreno, M.
A1  - Saul, J.
A1  - Eckelmann, F.
A1  - Palo, M.
A1  - Deng, Z.
A1  - Babeyko, Andrey
A1  - Chen, K.
A1  - Báez, Juan Carlos
A1  - Schurr, B.
A1  - Wang, R.
A1  - Dahm, Torsten
T1  - The 2015 Illapel earthquake, central Chile: A type case for a characteristic earthquake?
JF  - Geophysical research letters
N2  - On 16 September 2015, the M-W = 8.2 Illapel megathrust earthquake ruptured the Central Chilean margin. Combining inversions of displacement measurements and seismic waveforms with high frequency (HF) teleseismic backprojection, we derive a comprehensive description of the rupture, which also predicts deep ocean tsunami wave heights. We further determine moment tensors and obtain accurate depth estimates for the aftershock sequence. The earthquake nucleated near the coast but then propagated to the north and updip, attaining a peak slip of 5-6 m. In contrast, HF seismic radiation is mostly emitted downdip of the region of intense slip and arrests earlier than the long period rupture, indicating smooth slip along the shallow plate interface in the final phase. A superficially similar earthquake in 1943 with a similar aftershock zone had a much shorter source time function, which matches the duration of HF seismic radiation in the recent event, indicating that the 1943 event lacked the shallow slip.
Y1  - 2016
U6  - https://doi.org/10.1002/2015GL066963
SN  - 0094-8276
SN  - 1944-8007
VL  - 43
SP  - 574
EP  - 583
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Wang, Y.
A1  - Herzschuh, Ulrike
A1  - Shumilovskikh, L. S.
A1  - Mischke, Steffen
A1  - Birks, H. John B.
A1  - Wischnewski, J.
A1  - Böhner, Jürgen
A1  - Schluetz, F.
A1  - Lehmkuhl, F.
A1  - Diekmann, Bernhard
A1  - Wuennemann, B.
A1  - Zhang, C.
T1  - Open Access Quantitative reconstruction of precipitation changes on the NE Tibetan Plateau since the Last Glacial Maximum - extending the concept of pollen source area to pollen-based climate reconstructions from large lakes
JF  - Climate of the past : an interactive open access journal of the European Geosciences Union
N2  - Pollen records from large lakes have been used for quantitative palaeoclimate reconstruction, but the influences that lake size (as a result of species-specific variations in pollen dispersal patterns that smaller pollen grains are more easily transported to lake centre) and taphonomy have on these climatic signals have not previously been systematically investigated. We introduce the concept of pollen source area to pollen-based climate calibration using the north-eastern Tibetan Plateau as our study area. We present a pollen data set collected from large lakes in the arid to semi-arid region of central Asia. The influences that lake size and the inferred pollen source areas have on pollen compositions have been investigated through comparisons with pollen assemblages in neighbouring lakes of various sizes. Modern pollen samples collected from different parts of Lake Donggi Cona (in the north-eastern part of the Tibetan Plateau) reveal variations in pollen assemblages within this large lake, which are interpreted in terms of the species-specific dispersal and depositional patterns for different types of pollen, and in terms of fluvial input components. We have estimated the pollen source area for each lake individually and used this information to infer modern climate data with which to then develop a modern calibration data set, using both the multivariate regression tree (MRT) and weighted-averaging partial least squares (WA-PLS) approaches. Fossil pollen data from Lake Donggi Cona have been used to reconstruct the climate history of the north-eastern part of the Tibetan Plateau since the Last Glacial Maximum (LGM). The meanannual precipitation was quantitatively reconstructed using WA-PLS: extremely dry conditions are found to have dominated the LGM, with annual precipitation of around 100 mm, which is only 32% of present-day precipitation. A gradually increasing trend in moisture conditions during the Late Glacial is terminated by an abrupt reversion to a dry phase that lasts for about 1000 yr and coincides with "Heinrich event 1" in the North Atlantic region. Subsequent periods corresponding to the Bolling/Allerod interstadial, with annual precipitation (P-ann) of about 350 mm, and the Younger Dryas event (about 270 mm P-ann) are followed by moist conditions in the early Holocene, with annual precipitation of up to 400 mm. A drier trend after 9 cal. ka BP is followed by a second wet phase in the middle Holocene, lasting until 4.5 cal. ka BP. Relatively steady conditions with only slight fluctuations then dominate the late Holocene, resulting in the present climatic conditions. The climate changes since the LGM have been primarily driven by deglaciation and fluctuations in the intensity of the Asian summer monsoon that resulted from changes in the Northern Hemisphere summer solar insolation, as well as from changes in the North Atlantic climate through variations in the circulation patterns and intensity of the westerlies.
Y1  - 2014
U6  - https://doi.org/10.5194/cp-10-21-2014
SN  - 1814-9324
SN  - 1814-9332
VL  - 10
IS  - 1
SP  - 21
EP  - 39
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - GEN
A1  - Gorski, Mathias
A1  - Jung, Bettina
A1  - Li, Yong
A1  - Matias-Garcia, Pamela R.
A1  - Wuttke, Matthias
A1  - Coassin, Stefan
A1  - Thio, Chris H. L.
A1  - Kleber, Marcus E.
A1  - Winkler, Thomas W.
A1  - Wanner, Veronika
A1  - Chai, Jin-Fang
A1  - Chu, Audrey Y.
A1  - Cocca, Massimiliano
A1  - Feitosa, Mary F.
A1  - Ghasemi, Sahar
A1  - Hoppmann, Anselm
A1  - Horn, Katrin
A1  - Li, Man
A1  - Nutile, Teresa
A1  - Scholz, Markus
A1  - Sieber, Karsten B.
A1  - Teumer, Alexander
A1  - Tin, Adrienne
A1  - Wang, Judy
A1  - Tayo, Bamidele O.
A1  - Ahluwalia, Tarunveer S.
A1  - Almgren, Peter
A1  - Bakker, Stephan J. L.
A1  - Banas, Bernhard
A1  - Bansal, Nisha
A1  - Biggs, Mary L.
A1  - Boerwinkle, Eric
A1  - Böttinger, Erwin
A1  - Brenner, Hermann
A1  - Carroll, Robert J.
A1  - Chalmers, John
A1  - Chee, Miao-Li
A1  - Chee, Miao-Ling
A1  - Cheng, Ching-Yu
A1  - Coresh, Josef
A1  - de Borst, Martin H.
A1  - Degenhardt, Frauke
A1  - Eckardt, Kai-Uwe
A1  - Endlich, Karlhans
A1  - Franke, Andre
A1  - Freitag-Wolf, Sandra
A1  - Gampawar, Piyush
A1  - Gansevoort, Ron T.
A1  - Ghanbari, Mohsen
A1  - Gieger, Christian
A1  - Hamet, Pavel
A1  - Ho, Kevin
A1  - Hofer, Edith
A1  - Holleczek, Bernd
A1  - Foo, Valencia Hui Xian
A1  - Hutri-Kahonen, Nina
A1  - Hwang, Shih-Jen
A1  - Ikram, M. Arfan
A1  - Josyula, Navya Shilpa
A1  - Kahonen, Mika
A1  - Khor, Chiea-Chuen
A1  - Koenig, Wolfgang
A1  - Kramer, Holly
A1  - Kraemer, Bernhard K.
A1  - Kuehnel, Brigitte
A1  - Lange, Leslie A.
A1  - Lehtimaki, Terho
A1  - Lieb, Wolfgang
A1  - Loos, Ruth J. F.
A1  - Lukas, Mary Ann
A1  - Lyytikainen, Leo-Pekka
A1  - Meisinger, Christa
A1  - Meitinger, Thomas
A1  - Melander, Olle
A1  - Milaneschi, Yuri
A1  - Mishra, Pashupati P.
A1  - Mononen, Nina
A1  - Mychaleckyj, Josyf C.
A1  - Nadkarni, Girish N.
A1  - Nauck, Matthias
A1  - Nikus, Kjell
A1  - Ning, Boting
A1  - Nolte, Ilja M.
A1  - O'Donoghue, Michelle L.
A1  - Orho-Melander, Marju
A1  - Pendergrass, Sarah A.
A1  - Penninx, Brenda W. J. H.
A1  - Preuss, Michael H.
A1  - Psaty, Bruce M.
A1  - Raffield, Laura M.
A1  - Raitakari, Olli T.
A1  - Rettig, Rainer
A1  - Rheinberger, Myriam
A1  - Rice, Kenneth M.
A1  - Rosenkranz, Alexander R.
A1  - Rossing, Peter
A1  - Rotter, Jerome
A1  - Sabanayagam, Charumathi
A1  - Schmidt, Helena
A1  - Schmidt, Reinhold
A1  - Schoettker, Ben
A1  - Schulz, Christina-Alexandra
A1  - Sedaghat, Sanaz
A1  - Shaffer, Christian M.
A1  - Strauch, Konstantin
A1  - Szymczak, Silke
A1  - Taylor, Kent D.
A1  - Tremblay, Johanne
A1  - Chaker, Layal
A1  - van der Harst, Pim
A1  - van der Most, Peter J.
A1  - Verweij, Niek
A1  - Voelker, Uwe
A1  - Waldenberger, Melanie
A1  - Wallentin, Lars
A1  - Waterworth, Dawn M.
A1  - White, Harvey D.
A1  - Wilson, James G.
A1  - Wong, Tien-Yin
A1  - Woodward, Mark
A1  - Yang, Qiong
A1  - Yasuda, Masayuki
A1  - Yerges-Armstrong, Laura M.
A1  - Zhang, Yan
A1  - Snieder, Harold
A1  - Wanner, Christoph
A1  - Boger, Carsten A.
A1  - Kottgen, Anna
A1  - Kronenberg, Florian
A1  - Pattaro, Cristian
A1  - Heid, Iris M.
T1  - Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline
T2  - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät
N2  - Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function.
T3  - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät - 19 
KW  - acute kidney injury
KW  - end-stage kidney disease
KW  - genome-wide association
KW  - study
KW  - rapid eGFRcrea decline
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-565379
IS  - 19
ER  - 
TY  - JOUR
A1  - Gorski, Mathias
A1  - Jung, Bettina
A1  - Li, Yong
A1  - Matias-Garcia, Pamela R.
A1  - Wuttke, Matthias
A1  - Coassin, Stefan
A1  - Thio, Chris H. L.
A1  - Kleber, Marcus E.
A1  - Winkler, Thomas W.
A1  - Wanner, Veronika
A1  - Chai, Jin-Fang
A1  - Chu, Audrey Y.
A1  - Cocca, Massimiliano
A1  - Feitosa, Mary F.
A1  - Ghasemi, Sahar
A1  - Hoppmann, Anselm
A1  - Horn, Katrin
A1  - Li, Man
A1  - Nutile, Teresa
A1  - Scholz, Markus
A1  - Sieber, Karsten B.
A1  - Teumer, Alexander
A1  - Tin, Adrienne
A1  - Wang, Judy
A1  - Tayo, Bamidele O.
A1  - Ahluwalia, Tarunveer S.
A1  - Almgren, Peter
A1  - Bakker, Stephan J. L.
A1  - Banas, Bernhard
A1  - Bansal, Nisha
A1  - Biggs, Mary L.
A1  - Boerwinkle, Eric
A1  - Böttinger, Erwin
A1  - Brenner, Hermann
A1  - Carroll, Robert J.
A1  - Chalmers, John
A1  - Chee, Miao-Li
A1  - Chee, Miao-Ling
A1  - Cheng, Ching-Yu
A1  - Coresh, Josef
A1  - de Borst, Martin H.
A1  - Degenhardt, Frauke
A1  - Eckardt, Kai-Uwe
A1  - Endlich, Karlhans
A1  - Franke, Andre
A1  - Freitag-Wolf, Sandra
A1  - Gampawar, Piyush
A1  - Gansevoort, Ron T.
A1  - Ghanbari, Mohsen
A1  - Gieger, Christian
A1  - Hamet, Pavel
A1  - Ho, Kevin
A1  - Hofer, Edith
A1  - Holleczek, Bernd
A1  - Foo, Valencia Hui Xian
A1  - Hutri-Kahonen, Nina
A1  - Hwang, Shih-Jen
A1  - Ikram, M. Arfan
A1  - Josyula, Navya Shilpa
A1  - Kahonen, Mika
A1  - Khor, Chiea-Chuen
A1  - Koenig, Wolfgang
A1  - Kramer, Holly
A1  - Kraemer, Bernhard K.
A1  - Kuehnel, Brigitte
A1  - Lange, Leslie A.
A1  - Lehtimaki, Terho
A1  - Lieb, Wolfgang
A1  - Loos, Ruth J. F.
A1  - Lukas, Mary Ann
A1  - Lyytikainen, Leo-Pekka
A1  - Meisinger, Christa
A1  - Meitinger, Thomas
A1  - Melander, Olle
A1  - Milaneschi, Yuri
A1  - Mishra, Pashupati P.
A1  - Mononen, Nina
A1  - Mychaleckyj, Josyf C.
A1  - Nadkarni, Girish N.
A1  - Nauck, Matthias
A1  - Nikus, Kjell
A1  - Ning, Boting
A1  - Nolte, Ilja M.
A1  - O'Donoghue, Michelle L.
A1  - Orho-Melander, Marju
A1  - Pendergrass, Sarah A.
A1  - Penninx, Brenda W. J. H.
A1  - Preuss, Michael H.
A1  - Psaty, Bruce M.
A1  - Raffield, Laura M.
A1  - Raitakari, Olli T.
A1  - Rettig, Rainer
A1  - Rheinberger, Myriam
A1  - Rice, Kenneth M.
A1  - Rosenkranz, Alexander R.
A1  - Rossing, Peter
A1  - Rotter, Jerome
A1  - Sabanayagam, Charumathi
A1  - Schmidt, Helena
A1  - Schmidt, Reinhold
A1  - Schoettker, Ben
A1  - Schulz, Christina-Alexandra
A1  - Sedaghat, Sanaz
A1  - Shaffer, Christian M.
A1  - Strauch, Konstantin
A1  - Szymczak, Silke
A1  - Taylor, Kent D.
A1  - Tremblay, Johanne
A1  - Chaker, Layal
A1  - van der Harst, Pim
A1  - van der Most, Peter J.
A1  - Verweij, Niek
A1  - Voelker, Uwe
A1  - Waldenberger, Melanie
A1  - Wallentin, Lars
A1  - Waterworth, Dawn M.
A1  - White, Harvey D.
A1  - Wilson, James G.
A1  - Wong, Tien-Yin
A1  - Woodward, Mark
A1  - Yang, Qiong
A1  - Yasuda, Masayuki
A1  - Yerges-Armstrong, Laura M.
A1  - Zhang, Yan
A1  - Snieder, Harold
A1  - Wanner, Christoph
A1  - Boger, Carsten A.
A1  - Kottgen, Anna
A1  - Kronenberg, Florian
A1  - Pattaro, Cristian
A1  - Heid, Iris M.
T1  - Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline
JF  - Kidney international : official journal of the International Society of Nephrology
N2  - Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function.
KW  - acute kidney injury
KW  - end-stage kidney disease
KW  - genome-wide association
KW  - study
KW  - rapid eGFRcrea decline
Y1  - 2020
U6  - https://doi.org/10.1016/j.kint.2020.09.030
SN  - 0085-2538
SN  - 1523-1755
VL  - 99
IS  - 4
SP  - 926
EP  - 939
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Wilkin, Kyle J.
A1  - Parrish, Robert M.
A1  - Yang, Jie
A1  - Wolf, Thomas J. A.
A1  - Nunes, J. Pedro F.
A1  - Gühr, Markus
A1  - Li, Renkai
A1  - Shen, Xiaozhe
A1  - Zheng, Qiang
A1  - Wang, Xijie
A1  - Martinez, Todd J.
A1  - Centurion, Martin
T1  - Diffractive imaging of dissociation and ground-state dynamics in a complex molecule
JF  - Physical review : A, Atomic, molecular, and optical physics
N2  - We have investigated the structural dynamics in photoexcited 1,2-diiodotetrafluoroethane molecules (C2F4I2) in the gas phase experimentally using ultrafast electron diffraction and theoretically using FOMO-CASCI excited-state dynamics simulations. The molecules are excited by an ultraviolet femtosecond laser pulse to a state characterized by a transition from the iodine 5p perpendicular to orbital to a mixed 5p parallel to sigma hole and CF2 center dot antibonding orbital, which results in the cleavage of one of the carbon-iodine bonds. We have observed, with sub-Angstrom resolution, the motion of the nuclear wave packet of the dissociating iodine atom followed by coherent vibrations in the electronic ground state of the C2F4I radical. The radical reaches a stable classical (nonbridged) structure in less than 200 fs.
Y1  - 2019
U6  - https://doi.org/10.1103/PhysRevA.100.023402
SN  - 2469-9926
SN  - 2469-9934
VL  - 100
IS  - 2
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - JOUR
A1  - Yang, Jie
A1  - Zhu, Xiaolei
A1  - Wolf, Thomas J. A.
A1  - Li, Zheng
A1  - Nunes, João Pedro Figueira
A1  - Coffee, Ryan
A1  - Cryan, James P.
A1  - Gühr, Markus
A1  - Hegazy, Kareem
A1  - Heinz, Tony F.
A1  - Jobe, Keith
A1  - Li, Renkai
A1  - Shen, Xiaozhe
A1  - Veccione, Theodore
A1  - Weathersby, Stephen
A1  - Wilkin, Kyle J.
A1  - Yoneda, Charles
A1  - Zheng, Qiang
A1  - Martinez, Todd J.
A1  - Centurion, Martin
A1  - Wang, Xijie
T1  - Imaging CF3I conical intersection and photodissociation dynamics with ultrafast electron diffraction
JF  - Science
N2  - Conical intersections play a critical role in excited-state dynamics of polyatomic molecules because they govern the reaction pathways of many nonadiabatic processes. However, ultrafast probes have lacked sufficient spatial resolution to image wave-packet trajectories through these intersections directly. Here, we present the simultaneous experimental characterization of one-photon and two-photon excitation channels in isolated CF3I molecules using ultrafast gas-phase electron diffraction. In the two-photon channel, we have mapped out the real-space trajectories of a coherent nuclear wave packet, which bifurcates onto two potential energy surfaces when passing through a conical intersection. In the one-photon channel, we have resolved excitation of both the umbrella and the breathing vibrational modes in the CF3 fragment in multiple nuclear dimensions. These findings benchmark and validate ab initio nonadiabatic dynamics calculations.
Y1  - 2018
U6  - https://doi.org/10.1126/science.aat0049
SN  - 0036-8075
SN  - 1095-9203
VL  - 361
IS  - 6397
SP  - 64
EP  - 67
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  - 
TY  - JOUR
A1  - Wang, G.
A1  - Nespurek, S.
A1  - Rakusan, J.
A1  - Karaskova, M.
A1  - Schauer, F.
A1  - Brehmer, Ludwig
T1  - Polarized electrolumineseence from bilayer structures
N2  - The photoalignment ability of poly[methyl(phenyl)silylene] (PMPSi) films makes it possible to use them as hole- transporting substrates for the preparation of organic oriented films. A PMPSi layer prepared by spin coating was irradiated, after drying, with linearly polarized UV light. Then, water-soluble hydroxyaluminium phthalocyaninesulfonate [Al(OH)Pc(SO3Na)(1-2)] was deposited by casting. The cell ITO/PMPSi/AI(OH)Pc(SO3Na)(1-2)/Al showed non-linear current- voltage characteristics. For applied voltages higher than 10 V, polarized electroluminescence was observed. Its spectral characteristic consisted of two peaks with maxima at about 320 and 700 nm; their polarized anisotropies R-EL = Phi(parallel to) / Phi(perpendicular to) were ca. 15 and 0.5, respectively
Y1  - 2004
SN  - 1022-1360
ER  - 
TY  - GEN
A1  - Hodgkins, Suzanne B.
A1  - Richardson, Curtis J.
A1  - Dommain, René
A1  - Wang, Hongjun
A1  - Glaser, Paul H.
A1  - Verbeke, Brittany
A1  - Winkler, B. Rose
A1  - Cobb, Alexander R.
A1  - Rich, Virginia I.
A1  - Missilmani, Malak
A1  - Flanagan, Neal
A1  - Ho, Mengchi
A1  - Hoyt, Alison M.
A1  - Harvey, Charles F.
A1  - Vining, S. Rose
A1  - Hough, Moira A.
A1  - Moore, Tim R.
A1  - Richard, Pierre J. H.
A1  - De La Cruz, Florentino B.
A1  - Toufaily, Joumana
A1  - Hamdan, Rasha
A1  - Cooper, William T.
A1  - Chanton, Jeffrey P.
T1  - Tropical peatland carbon storage linked to global latitudinal trends in peat recalcitrance
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - Peatlands represent large terrestrial carbon banks. Given that most peat accumulates in boreal regions, where low temperatures and water saturation preserve organic matter, the existence of peat in (sub)tropical regions remains enigmatic. Here we examined peat and plant chemistry across a latitudinal transect from the Arctic to the tropics. Near-surface low-latitude peat has lower carbohydrate and greater aromatic content than near-surface high-latitude peat, creating a reduced oxidation state and resulting recalcitrance. This recalcitrance allows peat to persist in the (sub)tropics despite warm temperatures. Because we observed similar declines in carbohydrate content with depth in high-latitude peat, our data explain recent field-scale deep peat warming experiments in which catotelm (deeper) peat remained stable despite temperature increases up to 9 degrees C. We suggest that high-latitude deep peat reservoirs may be stabilized in the face of climate change by their ultimately lower carbohydrate and higher aromatic composition, similar to tropical peats.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1125 
KW  - dissolved organic matter
KW  - greenhouse gas fluxes
KW  - permafrost thaw
KW  - Northern Minnesota
KW  - FTIR spectroscopy
KW  - lignin content
KW  - brown rot
KW  - decomposition
KW  - chemistry
KW  - dynamics
Y1  - 2021
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-459658
SN  - 1866-8372
IS  - 1125
ER  - 
TY  - JOUR
A1  - Hodgkins, Suzanne B.
A1  - Richardson, Curtis J.
A1  - Dommain, Rene
A1  - Wang, Hongjun
A1  - Glaser, Paul H.
A1  - Verbeke, Brittany
A1  - Winkler, B. Rose
A1  - Cobb, Alexander R.
A1  - Rich, Virginia I.
A1  - Missilmani, Malak
A1  - Flanagan, Neal
A1  - Ho, Mengchi
A1  - Hoyt, Alison M.
A1  - Harvey, Charles F.
A1  - Vining, S. Rose
A1  - Hough, Moira A.
A1  - Moore, Tim R.
A1  - Richard, Pierre J. H.
A1  - De la Cruz, Florentino B.
A1  - Toufaily, Joumana
A1  - Hamdan, Rasha
A1  - Cooper, William T.
A1  - Chanton, Jeffrey P.
T1  - Tropical peatland carbon storage linked to global latitudinal trends in peat recalcitrance
JF  - Nature Communications
N2  - Peatlands represent large terrestrial carbon banks. Given that most peat accumulates in boreal regions, where low temperatures and water saturation preserve organic matter, the existence of peat in (sub)tropical regions remains enigmatic. Here we examined peat and plant chemistry across a latitudinal transect from the Arctic to the tropics. Near-surface low-latitude peat has lower carbohydrate and greater aromatic content than near-surface high-latitude peat, creating a reduced oxidation state and resulting recalcitrance. This recalcitrance allows peat to persist in the (sub)tropics despite warm temperatures. Because we observed similar declines in carbohydrate content with depth in high-latitude peat, our data explain recent field-scale deep peat warming experiments in which catotelm (deeper) peat remained stable despite temperature increases up to 9 degrees C. We suggest that high-latitude deep peat reservoirs may be stabilized in the face of climate change by their ultimately lower carbohydrate and higher aromatic composition, similar to tropical peats.
Y1  - 2018
U6  - https://doi.org/10.1038/s41467-018-06050-2
SN  - 2041-1723
VL  - 9
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Wolf, Thomas J. A.
A1  - Sanchez, David M.
A1  - Yang, J.
A1  - Parrish, R. M.
A1  - Nunes, J. P. F.
A1  - Centurion, M.
A1  - Coffee, R.
A1  - Cryan, J. P.
A1  - Gühr, Markus
A1  - Hegazy, Kareem
A1  - Kirrander, Adam
A1  - Li, R. K.
A1  - Ruddock, J.
A1  - Shen, Xiaozhe
A1  - Vecchione, T.
A1  - Weathersby, S. P.
A1  - Weber, Peter M.
A1  - Wilkin, K.
A1  - Yong, Haiwang
A1  - Zheng, Q.
A1  - Wang, X. J.
A1  - Minitti, Michael P.
A1  - Martinez, Todd J.
T1  - The photochemical ring-opening of 1,3-cyclohexadiene imaged by ultrafast electron diffraction
JF  - Nature chemistry
N2  - The ultrafast photoinduced ring-opening of 1,3-cyclohexadiene constitutes a textbook example of electrocyclic reactions in organic chemistry and a model for photobiological reactions in vitamin D synthesis. Although the relaxation from the photoexcited electronic state during the ring-opening has been investigated in numerous studies, the accompanying changes in atomic distance have not been resolved. Here we present a direct and unambiguous observation of the ring-opening reaction path on the femtosecond timescale and subangstrom length scale using megaelectronvolt ultrafast electron diffraction. We followed the carbon-carbon bond dissociation and the structural opening of the 1,3-cyclohexadiene ring by the direct measurement of time-dependent changes in the distribution of interatomic distances. We observed a substantial acceleration of the ring-opening motion after internal conversion to the ground state due to a steepening of the electronic potential gradient towards the product minima. The ring-opening motion transforms into rotation of the terminal ethylene groups in the photoproduct 1,3,5-hexatriene on the subpicosecond timescale.
KW  - Organic chemistry
KW  - Photochemistry
KW  - Physical chemistry
KW  - Theoretical chemistry
Y1  - 2019
U6  - https://doi.org/10.1038/s41557-019-0252-7
SN  - 1755-4330
SN  - 1755-4349
VL  - 11
IS  - 6
SP  - 504
EP  - 509
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Dengler, Jürgen
A1  - Wagner, Viktoria
A1  - Dembicz, Iwona
A1  - Garcia-Mijangos, Itziar
A1  - Naqinezhad, Alireza
A1  - Boch, Steffen
A1  - Chiarucci, Alessandro
A1  - Conradi, Timo
A1  - Filibeck, Goffredo
A1  - Guarino, Riccardo
A1  - Janisova, Monika
A1  - Steinbauer, Manuel J.
A1  - Acic, Svetlana
A1  - Acosta, Alicia T. R.
A1  - Akasaka, Munemitsu
A1  - Allers, Marc-Andre
A1  - Apostolova, Iva
A1  - Axmanova, Irena
A1  - Bakan, Branko
A1  - Baranova, Alina
A1  - Bardy-Durchhalter, Manfred
A1  - Bartha, Sandor
A1  - Baumann, Esther
A1  - Becker, Thomas
A1  - Becker, Ute
A1  - Belonovskaya, Elena
A1  - Bengtsson, Karin
A1  - Benito Alonso, Jose Luis
A1  - Berastegi, Asun
A1  - Bergamini, Ariel
A1  - Bonini, Ilaria
A1  - Bruun, Hans Henrik
A1  - Budzhak, Vasyl
A1  - Bueno, Alvaro
A1  - Antonio Campos, Juan
A1  - Cancellieri, Laura
A1  - Carboni, Marta
A1  - Chocarro, Cristina
A1  - Conti, Luisa
A1  - Czarniecka-Wiera, Marta
A1  - De Frenne, Pieter
A1  - Deak, Balazs
A1  - Didukh, Yakiv P.
A1  - Diekmann, Martin
A1  - Dolnik, Christian
A1  - Dupre, Cecilia
A1  - Ecker, Klaus
A1  - Ermakov, Nikolai
A1  - Erschbamer, Brigitta
A1  - Escudero, Adrian
A1  - Etayo, Javier
A1  - Fajmonova, Zuzana
A1  - Felde, Vivian A.
A1  - Fernandez Calzado, Maria Rosa
A1  - Finckh, Manfred
A1  - Fotiadis, Georgios
A1  - Fracchiolla, Mariano
A1  - Ganeva, Anna
A1  - Garcia-Magro, Daniel
A1  - Gavilan, Rosario G.
A1  - Germany, Markus
A1  - Giladi, Itamar
A1  - Gillet, Francois
A1  - Giusso del Galdo, Gian Pietro
A1  - Gonzalez, Jose M.
A1  - Grytnes, John-Arvid
A1  - Hajek, Michal
A1  - Hajkova, Petra
A1  - Helm, Aveliina
A1  - Herrera, Mercedes
A1  - Hettenbergerova, Eva
A1  - Hobohm, Carsten
A1  - Huellbusch, Elisabeth M.
A1  - Ingerpuu, Nele
A1  - Jandt, Ute
A1  - Jeltsch, Florian
A1  - Jensen, Kai
A1  - Jentsch, Anke
A1  - Jeschke, Michael
A1  - Jimenez-Alfaro, Borja
A1  - Kacki, Zygmunt
A1  - Kakinuma, Kaoru
A1  - Kapfer, Jutta
A1  - Kavgaci, Ali
A1  - Kelemen, Andras
A1  - Kiehl, Kathrin
A1  - Koyama, Asuka
A1  - Koyanagi, Tomoyo F.
A1  - Kozub, Lukasz
A1  - Kuzemko, Anna
A1  - Kyrkjeeide, Magni Olsen
A1  - Landi, Sara
A1  - Langer, Nancy
A1  - Lastrucci, Lorenzo
A1  - Lazzaro, Lorenzo
A1  - Lelli, Chiara
A1  - Leps, Jan
A1  - Loebel, Swantje
A1  - Luzuriaga, Arantzazu L.
A1  - Maccherini, Simona
A1  - Magnes, Martin
A1  - Malicki, Marek
A1  - Marceno, Corrado
A1  - Mardari, Constantin
A1  - Mauchamp, Leslie
A1  - May, Felix
A1  - Michelsen, Ottar
A1  - Mesa, Joaquin Molero
A1  - Molnar, Zsolt
A1  - Moysiyenko, Ivan Y.
A1  - Nakaga, Yuko K.
A1  - Natcheva, Rayna
A1  - Noroozi, Jalil
A1  - Pakeman, Robin J.
A1  - Palpurina, Salza
A1  - Partel, Meelis
A1  - Paetsch, Ricarda
A1  - Pauli, Harald
A1  - Pedashenko, Hristo
A1  - Peet, Robert K.
A1  - Pielech, Remigiusz
A1  - Pipenbaher, Natasa
A1  - Pirini, Chrisoula
A1  - Pleskova, Zuzana
A1  - Polyakova, Mariya A.
A1  - Prentice, Honor C.
A1  - Reinecke, Jennifer
A1  - Reitalu, Triin
A1  - Pilar Rodriguez-Rojo, Maria
A1  - Rolecek, Jan
A1  - Ronkin, Vladimir
A1  - Rosati, Leonardo
A1  - Rosen, Ejvind
A1  - Ruprecht, Eszter
A1  - Rusina, Solvita
A1  - Sabovljevic, Marko
A1  - Maria Sanchez, Ana
A1  - Savchenko, Galina
A1  - Schuhmacher, Oliver
A1  - Skornik, Sonja
A1  - Sperandii, Marta Gaia
A1  - Staniaszek-Kik, Monika
A1  - Stevanovic-Dajic, Zora
A1  - Stock, Marin
A1  - Suchrow, Sigrid
A1  - Sutcliffe, Laura M. E.
A1  - Swacha, Grzegorz
A1  - Sykes, Martin
A1  - Szabo, Anna
A1  - Talebi, Amir
A1  - Tanase, Catalin
A1  - Terzi, Massimo
A1  - Tolgyesi, Csaba
A1  - Torca, Marta
A1  - Torok, Peter
A1  - Tothmeresz, Bela
A1  - Tsarevskaya, Nadezda
A1  - Tsiripidis, Ioannis
A1  - Tzonev, Rossen
A1  - Ushimaru, Atushi
A1  - Valko, Orsolya
A1  - van der Maarel, Eddy
A1  - Vanneste, Thomas
A1  - Vashenyak, Iuliia
A1  - Vassilev, Kiril
A1  - Viciani, Daniele
A1  - Villar, Luis
A1  - Virtanen, Risto
A1  - Kosic, Ivana Vitasovic
A1  - Wang, Yun
A1  - Weiser, Frank
A1  - Went, Julia
A1  - Wesche, Karsten
A1  - White, Hannah
A1  - Winkler, Manuela
A1  - Zaniewski, Piotr T.
A1  - Zhang, Hui
A1  - Ziv, Yaron
A1  - Znamenskiy, Sergey
A1  - Biurrun, Idoia
T1  - GrassPlot - a database of multi-scale plant diversity in Palaearctic grasslands
JF  - Phytocoenologia
N2  - GrassPlot is a collaborative vegetation-plot database organised by the Eurasian Dry Grassland Group (EDGG) and listed in the Global Index of Vegetation-Plot Databases (GIVD ID EU-00-003). GrassPlot collects plot records (releves) from grasslands and other open habitats of the Palaearctic biogeographic realm. It focuses on precisely delimited plots of eight standard grain sizes (0.0001; 0.001;... 1,000 m(2)) and on nested-plot series with at least four different grain sizes. The usage of GrassPlot is regulated through Bylaws that intend to balance the interests of data contributors and data users. The current version (v. 1.00) contains data for approximately 170,000 plots of different sizes and 2,800 nested-plot series. The key components are richness data and metadata. However, most included datasets also encompass compositional data. About 14,000 plots have near-complete records of terricolous bryophytes and lichens in addition to vascular plants. At present, GrassPlot contains data from 36 countries throughout the Palaearctic, spread across elevational gradients and major grassland types. GrassPlot with its multi-scale and multi-taxon focus complements the larger international vegetationplot databases, such as the European Vegetation Archive (EVA) and the global database " sPlot". Its main aim is to facilitate studies on the scale-and taxon-dependency of biodiversity patterns and drivers along macroecological gradients. GrassPlot is a dynamic database and will expand through new data collection coordinated by the elected Governing Board. We invite researchers with suitable data to join GrassPlot. Researchers with project ideas addressable with GrassPlot data are welcome to submit proposals to the Governing Board.
KW  - biodiversity
KW  - European Vegetation Archive (EVA)
KW  - Eurasian Dry Grassland Group (EDGG)
KW  - grassland vegetation
KW  - GrassPlot
KW  - macroecology
KW  - multi-taxon
KW  - nested plot
KW  - scale-dependence
KW  - species-area relationship (SAR)
KW  - sPlot
KW  - vegetation-plot database
Y1  - 2018
U6  - https://doi.org/10.1127/phyto/2018/0267
SN  - 0340-269X
VL  - 48
IS  - 3
SP  - 331
EP  - 347
PB  - Cramer
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Sigman, Daniel M.
A1  - DiFiore, Peter J.
A1  - Hain, Mathis P.
A1  - Deutsch, Curtis
A1  - Wang, Yi
A1  - Karl, David M.
A1  - Knapp, Angela N.
A1  - Lehmann, Moritz F.
A1  - Pantoja, Silvio
T1  - The dual isotopes of deep nitrate as a constraint on the cycle and budget of oceanic fixed nitrogen
N2  - We compare the output of an 18-box geochemical model of the ocean with measurements to investigate the controls on both the mean values and variation of nitrate delta N-15 and delta O-18 in the ocean interior. The delta O-18 of nitrate is our focus because it has been explored less in previous work. Denitrification raises the delta N-15 and delta O-18 of mean ocean nitrate by equal amounts above their input values for N-2 fixation (for delta N-15) and nitrification (for delta O-18), generating parallel gradients in the delta N-15 and delta O-18 of deep ocean nitrate. Partial nitrate assimilation in the photic zone also causes equivalent increases in the delta N-15 and delta O-18 of the residual nitrate that can be transported into the interior. However, the regeneration and nitrification of sinking N can be said to decouple the N and O isotopes of deep ocean nitrate, especially when the sinking N is produced in a low latitude region, where nitrate consumption is effectively complete. The delta N-15 of the regenerated nitrate is equivalent to that originally consumed, whereas the regeneration replaces nitrate previously elevated in delta O-18 due to denitrification or nitrate assimilation with nitrate having the delta O-18 of nitrification. This lowers the delta O-18 of mean ocean nitrate and weakens nitrate delta O-18 gradients in the interior relative to those in delta N-15. This decoupling is characterized and quantified in the box model, and agreement with data shows its clear importance in the real ocean. At the same time, the model appears to generate overly strong gradients in both delta O-18 and delta N-15 within the ocean interior and a mean ocean nitrate delta O-18 that is higher than measured. This may be due to, in the model, too strong an impact of partial nitrate assimilation in the Southern Ocean on the delta N-15 and delta O-18 of preformed nitrate and/or too little cycling of intermediate-depth nitrate through the low latitude photic zone.
Y1  - 2009
UR  - http://www.sciencedirect.com/science/journal/09670637
U6  - https://doi.org/10.1016/j.dsr.2009.04.007
SN  - 0967-0637
ER  - 
TY  - JOUR
A1  - Sangoro, Joshia R.
A1  - Iacob, C.
A1  - Agapov, A. L.
A1  - Wang, Yangyang
A1  - Berdzinski, Stefan
A1  - Rexhausen, Hans
A1  - Strehmel, Veronika
A1  - Friedrich, C.
A1  - Sokolov, A. P.
A1  - Kremer, F.
T1  - Decoupling of ionic conductivity from structural dynamics in polymerized ionic liquids
JF  - Soft matter
N2  - Charge transport and structural dynamics in low molecular weight and polymerized 1-vinyl-3-pentylimidazolium bis(trifluoromethylsulfonyl) imide ionic liquids (ILs) are investigated by a combination of broadband dielectric spectroscopy, dynamic mechanical spectroscopy and differential scanning calorimetry. While the dc conductivity and fluidity exhibit practically identical temperature dependence for the non-polymerized IL, a significant decoupling of ionic conduction from structural dynamics is observed for the polymerized IL. In addition, the dc conductivity of the polymerized IL exceeds that of its molecular counterpart by four orders of magnitude at their respective calorimetric glass transition temperatures. This is attributed to the unusually high mobility of the anions especially at lower temperatures when the structural dynamics is significantly slowed down. A simple physical explanation of the possible origin of the remarkable decoupling of ionic conductivity from structural dynamics is proposed.
Y1  - 2014
U6  - https://doi.org/10.1039/c3sm53202j
SN  - 1744-683X
SN  - 1744-6848
VL  - 10
IS  - 20
SP  - 3536
EP  - 3540
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Evans, Nancy Remage
A1  - DeGioia-Eastwood, Kathleen
A1  - Gagne, Marc
A1  - Townsley, Leisa
A1  - Broos, Patrick S.
A1  - Wolk, Scott J.
A1  - Naze, Yael
A1  - Corcoran, Michael
A1  - Oskinova, Lida
A1  - Moffat, Anthony F. J.
A1  - Wang, Junfeng
A1  - Walborn, Nolan R.
T1  - The search for low-mass companions of b stars in the Carina Nebula cluster trumpler 16
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Supplement series
N2  - We have developed lists of likely B3-A0 stars (called "late B" stars) in the young cluster Trumpler 16. The following criteria were used: location within 3' of eta Car, an appropriate V and B - V combination, and proper motion (where available). Color and magnitude cuts have been made assuming an E(B - V) = 0.55 mag +/- 0.1, which is a good approximation close to the center of Trumpler 16. These lists have been cross-correlated with X-ray sources found in the Chandra Carina Complex Project. Previous studies have shown that only very rarely (if at all) do late main-sequence B stars produce X-rays. We present evidence that the X-ray-detected sources are binaries with low-mass companions, since stars less massive than 1.4 M-circle dot are strong X-ray sources at the age of the cluster. Both the median X-ray energies and X-ray luminosities of these sources are in good agreement with values for typical low-mass coronal X-ray sources. We find that 39% of the late B stars based on a list with proper motions have low-mass companions. Similarly, 32% of a sample without proper motions have low-mass companions. We discuss the X-ray detection completeness. These results on low-mass companions of intermediate-mass stars are complementary to spectroscopic and interferometric results and probe new parameter space of low-mass companions at all separations. They do not support a steeply rising distribution of mass ratios to low masses for intermediate-mass (5 M-circle dot) primaries, such as would be found by random pairing from the initial mass function.
KW  - open clusters and associations: individual (Trumpler 16)
KW  - stars: massive
Y1  - 2011
U6  - https://doi.org/10.1088/0067-0049/194/1/13
SN  - 0067-0049
VL  - 194
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Russell, C. M. P.
A1  - Corcoran, M. F.
A1  - Cuadra, J.
A1  - Owocki, S. P.
A1  - Wang, Q. D.
A1  - Hamaguchi, K.
A1  - Sugawara, Y.
A1  - Pollock, A. M. T.
A1  - Kallman, T. R.
T1  - Hydrodynamic and radiative transfer modeling of X-ray emission from colliding WR winds
BT  - WR 140 & the Galactic center
JF  - Wolf-Rayet Stars : Proceedings of an International Workshop held in Potsdam, Germany, 1.–5. June 2015
N2  - Colliding Wolf-Rayet (WR) winds produce thermal X-ray emission widely observed by X-ray telescopes. In wide WR+O binaries, such as WR 140, the X-ray flux is tied to the orbital phase, and is a direct probe of the winds’ properties. In the Galactic center, ~30 WRs orbit the super massive black hole (SMBH) within ~10”, leading to a smorgasbord of wind-wind collisions. To model the X-ray emission of WR 140 and the Galactic center, we perform 3D hydrodynamic simulations to trace the complex gaseous flows, and then carry out 3D radiative transfer calculations to compute the variable X-ray spectra. The model WR 140 RXTE light curve matches the data well for all phases except the X-ray minimum associated with periastron, while the model spectra agree with the RXTE hardness ratio and the shape of the Suzaku observations throughout the orbit. The Galactic center model of the Chandra flux and spectral shape match well in the region r ≤ 3”, but the model flux falls off too rapidly beyond this radius.
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-88255
SP  - 309
EP  - 312
ER  - 
TY  - JOUR
A1  - Bindschadler, Robert A.
A1  - Nowicki, Sophie
A1  - Abe-Ouchi, Ayako
A1  - Aschwanden, Andy
A1  - Choi, Hyeungu
A1  - Fastook, Jim
A1  - Granzow, Glen
A1  - Greve, Ralf
A1  - Gutowski, Gail
A1  - Herzfeld, Ute
A1  - Jackson, Charles
A1  - Johnson, Jesse
A1  - Khroulev, Constantine
A1  - Levermann, Anders
A1  - Lipscomb, William H.
A1  - Martin, Maria A.
A1  - Morlighem, Mathieu
A1  - Parizek, Byron R.
A1  - Pollard, David
A1  - Price, Stephen F.
A1  - Ren, Diandong
A1  - Saito, Fuyuki
A1  - Sato, Tatsuru
A1  - Seddik, Hakime
A1  - Seroussi, Helene
A1  - Takahashi, Kunio
A1  - Walker, Ryan
A1  - Wang, Wei Li
T1  - Ice-sheet model sensitivities to environmental forcing and their use in projecting future sea level (the SeaRISE project)
JF  - Journal of glaciology
N2  - Ten ice-sheet models are used to study sensitivity of the Greenland and Antarctic ice sheets to prescribed changes of surface mass balance, sub-ice-shelf melting and basal sliding. Results exhibit a large range in projected contributions to sea-level change. In most cases, the ice volume above flotation lost is linearly dependent on the strength of the forcing. Combinations of forcings can be closely approximated by linearly summing the contributions from single forcing experiments, suggesting that nonlinear feedbacks are modest. Our models indicate that Greenland is more sensitive than Antarctica to likely atmospheric changes in temperature and precipitation, while Antarctica is more sensitive to increased ice-shelf basal melting. An experiment approximating the Intergovernmental Panel on Climate Change's RCP8.5 scenario produces additional first-century contributions to sea level of 22.3 and 8.1 cm from Greenland and Antarctica, respectively, with a range among models of 62 and 14 cm, respectively. By 200 years, projections increase to 53.2 and 26.7 cm, respectively, with ranges of 79 and 43 cm. Linear interpolation of the sensitivity results closely approximates these projections, revealing the relative contributions of the individual forcings on the combined volume change and suggesting that total ice-sheet response to complicated forcings over 200 years can be linearized.
Y1  - 2013
U6  - https://doi.org/10.3189/2013JoG12J125
SN  - 0022-1430
VL  - 59
IS  - 214
SP  - 195
EP  - 224
PB  - International Glaciological Society
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Nowicki, Sophie
A1  - Bindschadler, Robert A.
A1  - Abe-Ouchi, Ayako
A1  - Aschwanden, Andy
A1  - Bueler, Ed
A1  - Choi, Hyeungu
A1  - Fastook, Jim
A1  - Granzow, Glen
A1  - Greve, Ralf
A1  - Gutowski, Gail
A1  - Herzfeld, Ute
A1  - Jackson, Charles
A1  - Johnson, Jesse
A1  - Khroulev, Constantine
A1  - Larour, Eric
A1  - Levermann, Anders
A1  - Lipscomb, William H.
A1  - Martin, Maria A.
A1  - Morlighem, Mathieu
A1  - Parizek, Byron R.
A1  - Pollard, David
A1  - Price, Stephen F.
A1  - Ren, Diandong
A1  - Rignot, Eric
A1  - Saito, Fuyuki
A1  - Sato, Tatsuru
A1  - Seddik, Hakime
A1  - Seroussi, Helene
A1  - Takahashi, Kunio
A1  - Walker, Ryan
A1  - Wang, Wei Li
T1  - Insights into spatial sensitivities of ice mass response to environmental change from the SeaRISE ice sheet modeling project II  Greenland
JF  - Journal of geophysical research : Earth surface
N2  - The Sea-level Response to Ice Sheet Evolution (SeaRISE) effort explores the sensitivity of the current generation of ice sheet models to external forcing to gain insight into the potential future contribution to sea level from the Greenland and Antarctic ice sheets. All participating models simulated the ice sheet response to three types of external forcings: a change in oceanic condition, a warmer atmospheric environment, and enhanced basal lubrication. Here an analysis of the spatial response of the Greenland ice sheet is presented, and the impact of model physics and spin-up on the projections is explored. Although the modeled responses are not always homogeneous, consistent spatial trends emerge from the ensemble analysis, indicating distinct vulnerabilities of the Greenland ice sheet. There are clear response patterns associated with each forcing, and a similar mass loss at the full ice sheet scale will result in different mass losses at the regional scale, as well as distinct thickness changes over the ice sheet. All forcings lead to an increased mass loss for the coming centuries, with increased basal lubrication and warmer ocean conditions affecting mainly outlet glaciers, while the impacts of atmospheric forcings affect the whole ice sheet.
KW  - Greenland
KW  - ice-sheet
KW  - sea-level
KW  - model
KW  - ensemble
Y1  - 2013
U6  - https://doi.org/10.1002/jgrf.20076
SN  - 2169-9003
VL  - 118
IS  - 2
SP  - 1025
EP  - 1044
PB  - American Geophysical Union
CY  - Washington
ER  - 
TY  - JOUR
A1  - Atsawawaranunt, Kamolphat
A1  - Comas-Bru, Laia
A1  - Mozhdehi, Sahar Amirnezhad
A1  - Deininger, Michael
A1  - Harrison, Sandy P.
A1  - Baker, Andy
A1  - Boyd, Meighan
A1  - Kaushal, Nikita
A1  - Ahmad, Syed Masood
A1  - Brahim, Yassine Ait
A1  - Arienzo, Monica
A1  - Bajo, Petra
A1  - Braun, Kerstin
A1  - Burstyn, Yuval
A1  - Chawchai, Sakonvan
A1  - Duan, Wuhui
A1  - Hatvani, Istvan Gabor
A1  - Hu, Jun
A1  - Kern, Zoltan
A1  - Labuhn, Inga
A1  - Lachniet, Matthew
A1  - Lechleitner, Franziska A.
A1  - Lorrey, Andrew
A1  - Perez-Mejias, Carlos
A1  - Pickering, Robyn
A1  - Scroxton, Nick
A1  - Atkinson, Tim
A1  - Ayalon, Avner
A1  - Baldini, James
A1  - Bar-Matthews, Miriam
A1  - Pablo Bernal, Juan
A1  - Breitenbach, Sebastian Franz Martin
A1  - Boch, Ronny
A1  - Borsato, Andrea
A1  - Cai, Yanjun
A1  - Carolin, Stacy
A1  - Cheng, Hai
A1  - Columbu, Andrea
A1  - Couchoud, Isabelle
A1  - Cruz, Francisco
A1  - Demeny, Attila
A1  - Dominguez-Villar, David
A1  - Dragusin, Virgil
A1  - Drysdale, Russell
A1  - Ersek, Vasile
A1  - Finne, Martin
A1  - Fleitmann, Dominik
A1  - Fohlmeister, Jens Bernd
A1  - Frappier, Amy
A1  - Genty, Dominique
A1  - Holzkamper, Steffen
A1  - Hopley, Philip
A1  - Kathayat, Gayatri
A1  - Keenan-Jones, Duncan
A1  - Koltai, Gabriella
A1  - Luetscher, Marc
A1  - Li, Ting-Yong
A1  - Lone, Mahjoor Ahmad
A1  - Markowska, Monika
A1  - Mattey, Dave
A1  - McDermott, Frank
A1  - Moreno, Ana
A1  - Moseley, Gina
A1  - Nehme, Carole
A1  - Novello, Valdir F.
A1  - Psomiadis, David
A1  - Rehfeld, Kira
A1  - Ruan, Jiaoyang
A1  - Sekhon, Natasha
A1  - Sha, Lijuan
A1  - Sholz, Denis
A1  - Shopov, Yavor
A1  - Smith, Andrew
A1  - Strikis, Nicolas
A1  - Treble, Pauline
A1  - Unal-Imer, Ezgi
A1  - Vaks, Anton
A1  - Vansteenberge, Stef
A1  - Veiga-Pires, Cristina
A1  - Voarintsoa, Ny Riavo
A1  - Wang, Xianfeng
A1  - Wong, Corinne
A1  - Wortham, Barbara
A1  - Wurtzel, Jennifer
A1  - Zong, Baoyun
T1  - The SISAL database
BT  - a global resource to document oxygen and carbon isotope records from speleothems
JF  - Earth System Science Data
N2  - Stable isotope records from speleothems provide information on past climate changes, most particularly information that can be used to reconstruct past changes in precipitation and atmospheric circulation. These records are increasingly being used to provide "out-of-sample" evaluations of isotope-enabled climate models. SISAL (Speleothem Isotope Synthesis and Analysis) is an international working group of the Past Global Changes (PAGES) project. The working group aims to provide a comprehensive compilation of speleothem isotope records for climate reconstruction and model evaluation. The SISAL database contains data for individual speleothems, grouped by cave system. Stable isotopes of oxygen and carbon (delta O-18, delta C-13) measurements are referenced by distance from the top or bottom of the speleothem. Additional tables provide information on dating, including information on the dates used to construct the original age model and sufficient information to assess the quality of each data set and to erect a standardized chronology across different speleothems. The metadata table provides location information, information on the full range of measurements carried out on each speleothem and information on the cave system that is relevant to the interpretation of the records, as well as citations for both publications and archived data.
Y1  - 2018
U6  - https://doi.org/10.5194/essd-10-1687-2018
SN  - 1866-3508
SN  - 1866-3516
VL  - 10
IS  - 3
SP  - 1687
EP  - 1713
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Comas-Bru, Laia
A1  - Harrison, Sandy P.
A1  - Werner, Martin
A1  - Rehfeld, Kira
A1  - Scroxton, Nick
A1  - Veiga-Pires, Cristina
A1  - Ahmad, Syed Masood
A1  - Brahim, Yassine Ait
A1  - Mozhdehi, Sahar Amirnezhad
A1  - Arienzo, Monica
A1  - Atsawawaranunt, Kamolphat
A1  - Baker, Andy
A1  - Braun, Kerstin
A1  - Breitenbach, Sebastian Franz Martin
A1  - Burstyn, Yuval
A1  - Chawchai, Sakonvan
A1  - Columbu, Andrea
A1  - Deininger, Michael
A1  - Demeny, Attila
A1  - Dixon, Bronwyn
A1  - Hatvani, Istvan Gabor
A1  - Hu, Jun
A1  - Kaushal, Nikita
A1  - Kern, Zoltan
A1  - Labuhn, Inga
A1  - Lachniet, Matthew S.
A1  - Lechleitner, Franziska A.
A1  - Lorrey, Andrew
A1  - Markowska, Monika
A1  - Nehme, Carole
A1  - Novello, Valdir F.
A1  - Oster, Jessica
A1  - Perez-Mejias, Carlos
A1  - Pickering, Robyn
A1  - Sekhon, Natasha
A1  - Wang, Xianfeng
A1  - Warken, Sophie
A1  - Atkinson, Tim
A1  - Ayalon, Avner
A1  - Baldini, James
A1  - Bar-Matthews, Miryam
A1  - Bernal, Juan Pablo
A1  - Boch, Ronny
A1  - Borsato, Andrea
A1  - Boyd, Meighan
A1  - Brierley, Chris
A1  - Cai, Yanjun
A1  - Carolin, Stacy
A1  - Cheng, Hai
A1  - Constantin, Silviu
A1  - Couchoud, Isabelle
A1  - Cruz, Francisco
A1  - Denniston, Rhawn
A1  - Dragusin, Virgil
A1  - Duan, Wuhui
A1  - Ersek, Vasile
A1  - Finne, Martin
A1  - Fleitmann, Dominik
A1  - Fohlmeister, Jens Bernd
A1  - Frappier, Amy
A1  - Genty, Dominique
A1  - Holzkamper, Steffen
A1  - Hopley, Philip
A1  - Johnston, Vanessa
A1  - Kathayat, Gayatri
A1  - Keenan-Jones, Duncan
A1  - Koltai, Gabriella
A1  - Li, Ting-Yong
A1  - Lone, Mahjoor Ahmad
A1  - Luetscher, Marc
A1  - Mattey, Dave
A1  - Moreno, Ana
A1  - Moseley, Gina
A1  - Psomiadis, David
A1  - Ruan, Jiaoyang
A1  - Scholz, Denis
A1  - Sha, Lijuan
A1  - Smith, Andrew Christopher
A1  - Strikis, Nicolas
A1  - Treble, Pauline
A1  - Unal-Imer, Ezgi
A1  - Vaks, Anton
A1  - Vansteenberge, Stef
A1  - Voarintsoa, Ny Riavo G.
A1  - Wong, Corinne
A1  - Wortham, Barbara
A1  - Wurtzel, Jennifer
A1  - Zhang, Haiwei
T1  - Evaluating model outputs using integrated global speleothem records of climate change since the last glacial
JF  - Climate of the past : an interactive open access journal of the European Geosciences Union
N2  - Although quantitative isotope data from speleothems has been used to evaluate isotope-enabled model simulations, currently no consensus exists regarding the most appropriate methodology through which to achieve this. A number of modelling groups will be running isotope-enabled palaeoclimate simulations in the framework of the Coupled Model Intercomparison Project Phase 6, so it is timely to evaluate different approaches to using the speleothem data for data–model comparisons. Here, we illustrate this using 456 globally distributed speleothem δ18O records from an updated version of the Speleothem Isotopes Synthesis and Analysis (SISAL) database and palaeoclimate simulations generated using the ECHAM5-wiso isotope-enabled atmospheric circulation model. We show that the SISAL records reproduce the first-order spatial patterns of isotopic variability in the modern day, strongly supporting the application of this dataset for evaluating model-derived isotope variability into the past. However, the discontinuous nature of many speleothem records complicates the process of procuring large numbers of records if data–model comparisons are made using the traditional approach of comparing anomalies between a control period and a given palaeoclimate experiment. To circumvent this issue, we illustrate techniques through which the absolute isotope values during any time period could be used for model evaluation. Specifically, we show that speleothem isotope records allow an assessment of a model's ability to simulate spatial isotopic trends. Our analyses provide a protocol for using speleothem isotope data for model evaluation, including screening the observations to take into account the impact of speleothem mineralogy on δ18O values, the optimum period for the modern observational baseline and the selection of an appropriate time window for creating means of the isotope data for palaeo-time-slices.
Y1  - 2019
U6  - https://doi.org/10.5194/cp-15-1557-2019
SN  - 1814-9324
SN  - 1814-9332
VL  - 15
IS  - 4
SP  - 1557
EP  - 1579
PB  - Copernicus
CY  - Göttingen
ER  - 
TY  - JOUR
A1  - Zhang, Zhihao
A1  - Wang, Ting
A1  - Kuang, Jin
A1  - Herold, Fabian
A1  - Ludyga, Sebastian
A1  - Li, Jingming
A1  - Hall, Daniel L.
A1  - Taylor, Alyx
A1  - Healy, Sean
A1  - Yeung, Albert S.
A1  - Kramer, Arthur F.
A1  - Zou, Liye
T1  - The roles of exercise tolerance and resilience in the effect of physical activity on emotional states among college students
JF  - International Journal of Clinical and Health Psychology
N2  - Background/objective: Negative emotional states, such as depression, anxiety, and stress challenge health care due to their long-term consequences for mental disorders. Accumulating evidence indicates that regular physical activity (PA) can positively influence negative emotional states. Among possible candidates, resilience and exercise tolerance in particular have the potential to partly explain the positive effects of PA on negative emotional states. Thus, the aim of this study was to investigate the association between PA and negative emotional states, and further determine the mediating effects of exercise tolerance and resilience in such a relationship. Method: In total, 1117 Chinese college students (50.4% female, Mage=18.90, SD=1.25) completed a psychosocial battery, including the 21-item Depression Anxiety Stress Scale (DASS-21), the Connor-Davidson Resilience Scale (CD-RISC), the Preference for and Tolerance of the Intensity of Exercise Questionnaire (PRETIE-Q), and the International Physical Activity Questionnaire short form (IPAQ-SF). Regression analysis was used to identify the serial multiple mediation, controlling for gender, age and BMI. Results: PA, exercise intensity-tolerance, and resilience were significantly negatively correlated with negative emotional states (Ps<.05). Further, exercise tolerance and resilience partially mediated the relationship between PA and negative emotional states. Conclusions: Resilience and exercise intensity-tolerance can be achieved through regularly engaging in PA, and these newly observed variables play critical roles in prevention of mental illnesses, especially college students who face various challenges. Recommended amount of PA should be incorporated into curriculum or sport clubs within a campus environment.
KW  - Exercise tolerance
KW  - Resilience
KW  - Physical activity
KW  - Emotion
KW  - Depression
Y1  - 2022
U6  - https://doi.org/10.1016/j.ijchp.2022.100312
SN  - 1697-2600
SN  - 1576-7329
VL  - 22
IS  - 3
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Tiegs, Scott D.
A1  - Costello, David M.
A1  - Isken, Mark W.
A1  - Woodward, Guy
A1  - McIntyre, Peter B.
A1  - Gessner, Mark O.
A1  - Chauvet, Eric
A1  - Griffiths, Natalie A.
A1  - Flecker, Alex S.
A1  - Acuna, Vicenc
A1  - Albarino, Ricardo
A1  - Allen, Daniel C.
A1  - Alonso, Cecilia
A1  - Andino, Patricio
A1  - Arango, Clay
A1  - Aroviita, Jukka
A1  - Barbosa, Marcus V. M.
A1  - Barmuta, Leon A.
A1  - Baxter, Colden V.
A1  - Bell, Thomas D. C.
A1  - Bellinger, Brent
A1  - Boyero, Luz
A1  - Brown, Lee E.
A1  - Bruder, Andreas
A1  - Bruesewitz, Denise A.
A1  - Burdon, Francis J.
A1  - Callisto, Marcos
A1  - Canhoto, Cristina
A1  - Capps, Krista A.
A1  - Castillo, Maria M.
A1  - Clapcott, Joanne
A1  - Colas, Fanny
A1  - Colon-Gaud, Checo
A1  - Cornut, Julien
A1  - Crespo-Perez, Veronica
A1  - Cross, Wyatt F.
A1  - Culp, Joseph M.
A1  - Danger, Michael
A1  - Dangles, Olivier
A1  - de Eyto, Elvira
A1  - Derry, Alison M.
A1  - Diaz Villanueva, Veronica
A1  - Douglas, Michael M.
A1  - Elosegi, Arturo
A1  - Encalada, Andrea C.
A1  - Entrekin, Sally
A1  - Espinosa, Rodrigo
A1  - Ethaiya, Diana
A1  - Ferreira, Veronica
A1  - Ferriol, Carmen
A1  - Flanagan, Kyla M.
A1  - Fleituch, Tadeusz
A1  - Shah, Jennifer J. Follstad
A1  - Frainer, Andre
A1  - Friberg, Nikolai
A1  - Frost, Paul C.
A1  - Garcia, Erica A.
A1  - Lago, Liliana Garcia
A1  - Garcia Soto, Pavel Ernesto
A1  - Ghate, Sudeep
A1  - Giling, Darren P.
A1  - Gilmer, Alan
A1  - Goncalves, Jose Francisco
A1  - Gonzales, Rosario Karina
A1  - Graca, Manuel A. S.
A1  - Grace, Mike
A1  - Grossart, Hans-Peter
A1  - Guerold, Francois
A1  - Gulis, Vlad
A1  - Hepp, Luiz U.
A1  - Higgins, Scott
A1  - Hishi, Takuo
A1  - Huddart, Joseph
A1  - Hudson, John
A1  - Imberger, Samantha
A1  - Iniguez-Armijos, Carlos
A1  - Iwata, Tomoya
A1  - Janetski, David J.
A1  - Jennings, Eleanor
A1  - Kirkwood, Andrea E.
A1  - Koning, Aaron A.
A1  - Kosten, Sarian
A1  - Kuehn, Kevin A.
A1  - Laudon, Hjalmar
A1  - Leavitt, Peter R.
A1  - Lemes da Silva, Aurea L.
A1  - Leroux, Shawn J.
A1  - Leroy, Carri J.
A1  - Lisi, Peter J.
A1  - MacKenzie, Richard
A1  - Marcarelli, Amy M.
A1  - Masese, Frank O.
A1  - Mckie, Brendan G.
A1  - Oliveira Medeiros, Adriana
A1  - Meissner, Kristian
A1  - Milisa, Marko
A1  - Mishra, Shailendra
A1  - Miyake, Yo
A1  - Moerke, Ashley
A1  - Mombrikotb, Shorok
A1  - Mooney, Rob
A1  - Moulton, Tim
A1  - Muotka, Timo
A1  - Negishi, Junjiro N.
A1  - Neres-Lima, Vinicius
A1  - Nieminen, Mika L.
A1  - Nimptsch, Jorge
A1  - Ondruch, Jakub
A1  - Paavola, Riku
A1  - Pardo, Isabel
A1  - Patrick, Christopher J.
A1  - Peeters, Edwin T. H. M.
A1  - Pozo, Jesus
A1  - Pringle, Catherine
A1  - Prussian, Aaron
A1  - Quenta, Estefania
A1  - Quesada, Antonio
A1  - Reid, Brian
A1  - Richardson, John S.
A1  - Rigosi, Anna
A1  - Rincon, Jose
A1  - Risnoveanu, Geta
A1  - Robinson, Christopher T.
A1  - Rodriguez-Gallego, Lorena
A1  - Royer, Todd V.
A1  - Rusak, James A.
A1  - Santamans, Anna C.
A1  - Selmeczy, Geza B.
A1  - Simiyu, Gelas
A1  - Skuja, Agnija
A1  - Smykla, Jerzy
A1  - Sridhar, Kandikere R.
A1  - Sponseller, Ryan
A1  - Stoler, Aaron
A1  - Swan, Christopher M.
A1  - Szlag, David
A1  - Teixeira-de Mello, Franco
A1  - Tonkin, Jonathan D.
A1  - Uusheimo, Sari
A1  - Veach, Allison M.
A1  - Vilbaste, Sirje
A1  - Vought, Lena B. M.
A1  - Wang, Chiao-Ping
A1  - Webster, Jackson R.
A1  - Wilson, Paul B.
A1  - Woelfl, Stefan
A1  - Xenopoulos, Marguerite A.
A1  - Yates, Adam G.
A1  - Yoshimura, Chihiro
A1  - Yule, Catherine M.
A1  - Zhang, Yixin X.
A1  - Zwart, Jacob A.
T1  - Global patterns and drivers of ecosystem functioning in rivers and riparian zones
JF  - Science Advances
N2  - River ecosystems receive and process vast quantities of terrestrial organic carbon, the fate of which depends strongly on microbial activity. Variation in and controls of processing rates, however, are poorly characterized at the global scale. In response, we used a peer-sourced research network and a highly standardized carbon processing assay to conduct a global-scale field experiment in greater than 1000 river and riparian sites. We found that Earth’s biomes have distinct carbon processing signatures. Slow processing is evident across latitudes, whereas rapid rates are restricted to lower latitudes. Both the mean rate and variability decline with latitude, suggesting temperature constraints toward the poles and greater roles for other environmental drivers (e.g., nutrient loading) toward the equator. These results and data set the stage for unprecedented “next-generation biomonitoring” by establishing baselines to help quantify environmental impacts to the functioning of ecosystems at a global scale.
Y1  - 2019
U6  - https://doi.org/10.1126/sciadv.aav0486
SN  - 2375-2548
VL  - 5
IS  - 1
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  -