TY  - JOUR
A1  - Abeysekara, A. U.
A1  - Benbow, Wystan
A1  - Bird, Ralph
A1  - Brill, A.
A1  - Brose, Robert
A1  - Buckley, J. H.
A1  - Chromey, A. J.
A1  - Daniel, M. K.
A1  - Falcone, A.
A1  - Finley, J. P.
A1  - Fortson, L.
A1  - Furniss, Amy
A1  - Gent, A.
A1  - Gillanders, Gerald H.
A1  - Hanna, David
A1  - Hassan, T.
A1  - Hervet, O.
A1  - Holder, J.
A1  - Hughes, G.
A1  - Humensky, T. B.
A1  - Kaaret, Philip
A1  - Kar, P.
A1  - Kertzman, M.
A1  - Kieda, David
A1  - Krause, Maria
A1  - Krennrich, F.
A1  - Kumar, S.
A1  - Lang, M. J.
A1  - Lin, T. T. Y.
A1  - Maier, Gernot
A1  - Moriarty, P.
A1  - Mukherjee, Reshmi
A1  - Ong, R. A.
A1  - Otte, Adam Nepomuk
A1  - Park, Nahee
A1  - Petrashyk, A.
A1  - Pohl, Martin
A1  - Pueschel, Elisa
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Richards, Gregory T.
A1  - Roache, E.
A1  - Sadeh, I.
A1  - Santander, Marcos
A1  - Schlenstedt, S.
A1  - Sembroski, G. H.
A1  - Sushch, Iurii
A1  - Tyler, J.
A1  - Vassiliev, V. V.
A1  - Wakely, S. P.
A1  - Weinstein, A.
A1  - Wells, R. M.
A1  - Wilcox, P.
A1  - Wilhelm, Alina
A1  - Williams, David A.
A1  - Williamson, T. J.
A1  - Zitzer, B.
A1  - Acciari, V. A.
A1  - Ansoldi, S.
A1  - Antonelli, L. A.
A1  - Engels, A. Arbet
A1  - Baack, D.
A1  - Babic, A.
A1  - Banerjee, B.
A1  - de Almeida, U. Barres
A1  - Barrio, J. A.
A1  - Becerra Gonzalez, Josefa
A1  - Bednarek, Wlodek
A1  - Bernardini, Elisa
A1  - Berti, A.
A1  - Besenrieder, J.
A1  - Bhattacharyya, W.
A1  - Bigongiari, C.
A1  - Biland, A.
A1  - Blanch, O.
A1  - Bonnoli, G.
A1  - Busetto, G.
A1  - Carosi, R.
A1  - Ceribella, G.
A1  - Cikota, S.
A1  - Colak, S. M.
A1  - Colin, P.
A1  - Colombo, E.
A1  - Contreras, J. L.
A1  - Cortina, J.
A1  - Covino, S.
A1  - Da Vela, P.
A1  - Dazzi, F.
A1  - De Angelis, A.
A1  - De Lotto, B.
A1  - Delfino, M.
A1  - Delgado, J.
A1  - Di Pierro, F.
A1  - Do Souto Espinera, E.
A1  - Dominguez, A.
A1  - Prester, D. Dominis
A1  - Dorner, D.
A1  - Doro, M.
A1  - Einecke, S.
A1  - Elsaesser, D.
A1  - Ramazani, V. Fallah
A1  - Fattorini, A.
A1  - Fernandez-Barral, A.
A1  - Ferrara, G.
A1  - Fidalgo, D.
A1  - Foffano, L.
A1  - Fonseca, M. V.
A1  - Font, L.
A1  - Fruck, C.
A1  - Galindo, D.
A1  - Gallozzi, S.
A1  - Lopez, R. J. Garcia
A1  - Garczarczyk, M.
A1  - Gasparyan, S.
A1  - Gaug, Markus
A1  - Giammaria, P.
A1  - Godinovic, N.
A1  - Guberman, D.
A1  - Hadasch, D.
A1  - Hahn, A.
A1  - Herrera, J.
A1  - Hoang, J.
A1  - Hrupec, D.
A1  - Inoue, S.
A1  - Ishio, K.
A1  - Iwamura, Y.
A1  - Kubo, H.
A1  - Kushida, J.
A1  - Kuvezdic, D.
A1  - Lamastra, A.
A1  - Lelas, D.
A1  - Leone, Francesco
A1  - Lindfors, E.
A1  - Lombardi, S.
A1  - Longo, Francesco
A1  - Lopez, M.
A1  - Lopez-Oramas, A.
A1  - Machado de Oliveira Fraga, B.
A1  - Maggio, C.
A1  - Majumdar, P.
A1  - Makariev, M.
A1  - Mallamaci, M.
A1  - Maneva, G.
A1  - Manganaro, M.
A1  - Mannheim, K.
A1  - Maraschi, L.
A1  - Mariotti, M.
A1  - Martinez, M.
A1  - Masuda, S.
A1  - Mazin, D.
A1  - Minev, M.
A1  - Miranda, J. M.
A1  - Mirzoyan, R.
A1  - Molina, E.
A1  - Moralejo, A.
A1  - Moreno, V.
A1  - Moretti, E.
A1  - Munar-Adrover, Pere
A1  - Neustroev, V.
A1  - Niedzwiecki, Andrzej
A1  - Rosillo, Mireia Nievas
A1  - Nigro, C.
A1  - Nilsson, Kari
A1  - Ninci, D.
A1  - Nishijima, K.
A1  - Noda, K.
A1  - Nogues, L.
A1  - Noethe, M.
A1  - Paiano, Simona
A1  - Palacio, J.
A1  - Paneque, D.
A1  - Paoletti, R.
A1  - Paredes, J. M.
A1  - Pedaletti, G.
A1  - Penil, P.
A1  - Peresano, M.
A1  - Persic, M.
A1  - Moroni, P. G. Prada
A1  - Prandini, E.
A1  - Puljak, I.
A1  - Garcia, J. R.
A1  - Rhode, W.
A1  - Ribo, Marc
A1  - Rico, J.
A1  - Righi, C.
A1  - Rugliancich, A.
A1  - Saha, Lab
A1  - Sahakyan, Narek
A1  - Saito, T.
A1  - Satalecka, K.
A1  - Schweizer, T.
A1  - Sitarek, J.
A1  - Snidaric, I.
A1  - Sobczynska, D.
A1  - Somero, A.
A1  - Stamerra, A.
A1  - Strzys, M.
A1  - Suric, T.
A1  - Tavecchio, Fabrizio
A1  - Temnikov, P.
A1  - Terzic, T.
A1  - Teshima, M.
A1  - Torres-Alba, N.
A1  - Tsujimoto, S.
A1  - van Scherpenberg, J.
A1  - Vanzo, G.
A1  - Vazquez Acosta, M.
A1  - Vovk, I.
A1  - Will, M.
A1  - Zaric, D.
T1  - Periastron Observations of TeV Gamma-Ray Emission from a Binary System with a 50-year Period
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters
N2  - We report on observations of the pulsar/Be star binary system PSR J2032+4127/MT91 213 in the energy range between 100 GeV and 20 TeV with the Very Energetic Radiation Imaging Telescope Array and Major Atmospheric Gamma Imaging Cherenkov telescope arrays. The binary orbit has a period of approximately 50 years, with the most recent periastron occurring on 2017 November 13. Our observations span from 18 months prior to periastron to one month after. A new point-like gamma-ray source is detected, coincident with the location of PSR J2032+4127/MT91 213. The gamma-ray light curve and spectrum are well characterized over the periastron passage. The flux is variable over at least an order of magnitude, peaking at periastron, thus providing a firm association of the TeV source with the pulsar/Be star system. Observations prior to periastron show a cutoff in the spectrum at an energy around 0.5 TeV. This result adds a new member to the small population of known TeV binaries, and it identifies only the second source of this class in which the nature and properties of the compact object are firmly established. We compare the gamma-ray results with the light curve measured with the X-ray Telescope on board the Neil Gehrels Swift Observatory and with the predictions of recent theoretical models of the system. We conclude that significant revision of the models is required to explain the details of the emission that we have observed, and we discuss the relationship between the binary system and the overlapping steady extended source, TeV J2032+4130.
KW  - gamma rays: general
KW  - pulsars: individual (PSR J2032+4127, VER J2032+414, MAGIC J2032+4127)
KW  - stars: individual (MT91 213)
KW  - X-rays: binaries
Y1  - 2018
U6  - https://doi.org/10.3847/2041-8213/aae70e
SN  - 2041-8205
SN  - 2041-8213
VL  - 867
IS  - 1
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Horikoshi, Momoko
A1  - Yaghootkar, Hanieh
A1  - Mook-Kanamori, Dennis O.
A1  - Sovio, Ulla
A1  - Taal, H. Rob
A1  - Hennig, Branwen J.
A1  - Bradfield, Jonathan P.
A1  - St Pourcain, Beate
A1  - Evans, David M.
A1  - Charoen, Pimphen
A1  - Kaakinen, Marika
A1  - Cousminer, Diana L.
A1  - Lehtimaki, Terho
A1  - Kreiner-Moller, Eskil
A1  - Warrington, Nicole M.
A1  - Bustamante, Mariona
A1  - Feenstra, Bjarke
A1  - Berry, Diane J.
A1  - Thiering, Elisabeth
A1  - Pfab, Thiemo
A1  - Barton, Sheila J.
A1  - Shields, Beverley M.
A1  - Kerkhof, Marjan
A1  - van Leeuwen, Elisabeth M.
A1  - Fulford, Anthony J.
A1  - Kutalik, Zoltan
A1  - Zhao, Jing Hua
A1  - den Hoed, Marcel
A1  - Mahajan, Anubha
A1  - Lindi, Virpi
A1  - Goh, Liang-Kee
A1  - Hottenga, Jouke-Jan
A1  - Wu, Ying
A1  - Raitakari, Olli T.
A1  - Harder, Marie N.
A1  - Meirhaeghe, Aline
A1  - Ntalla, Ioanna
A1  - Salem, Rany M.
A1  - Jameson, Karen A.
A1  - Zhou, Kaixin
A1  - Monies, Dorota M.
A1  - Lagou, Vasiliki
A1  - Kirin, Mirna
A1  - Heikkinen, Jani
A1  - Adair, Linda S.
A1  - Alkuraya, Fowzan S.
A1  - Al-Odaib, Ali
A1  - Amouyel, Philippe
A1  - Andersson, Ehm Astrid
A1  - Bennett, Amanda J.
A1  - Blakemore, Alexandra I. F.
A1  - Buxton, Jessica L.
A1  - Dallongeville, Jean
A1  - Das, Shikta
A1  - de Geus, Eco J. C.
A1  - Estivill, Xavier
A1  - Flexeder, Claudia
A1  - Froguel, Philippe
A1  - Geller, Frank
A1  - Godfrey, Keith M.
A1  - Gottrand, Frederic
A1  - Groves, Christopher J.
A1  - Hansen, Torben
A1  - Hirschhorn, Joel N.
A1  - Hofman, Albert
A1  - Hollegaard, Mads V.
A1  - Hougaard, David M.
A1  - Hyppoenen, Elina
A1  - Inskip, Hazel M.
A1  - Isaacs, Aaron
A1  - Jorgensen, Torben
A1  - Kanaka-Gantenbein, Christina
A1  - Kemp, John P.
A1  - Kiess, Wieland
A1  - Kilpelainen, Tuomas O.
A1  - Klopp, Norman
A1  - Knight, Bridget A.
A1  - Kuzawa, Christopher W.
A1  - McMahon, George
A1  - Newnham, John P.
A1  - Niinikoski, Harri
A1  - Oostra, Ben A.
A1  - Pedersen, Louise
A1  - Postma, Dirkje S.
A1  - Ring, Susan M.
A1  - Rivadeneira, Fernando
A1  - Robertson, Neil R.
A1  - Sebert, Sylvain
A1  - Simell, Olli
A1  - Slowinski, Torsten
A1  - Tiesler, Carla M. T.
A1  - Toenjes, Anke
A1  - Vaag, Allan
A1  - Viikari, Jorma S.
A1  - Vink, Jacqueline M.
A1  - Vissing, Nadja Hawwa
A1  - Wareham, Nicholas J.
A1  - Willemsen, Gonneke
A1  - Witte, Daniel R.
A1  - Zhang, Haitao
A1  - Zhao, Jianhua
A1  - Wilson, James F.
A1  - Stumvoll, Michael
A1  - Prentice, Andrew M.
A1  - Meyer, Brian F.
A1  - Pearson, Ewan R.
A1  - Boreham, Colin A. G.
A1  - Cooper, Cyrus
A1  - Gillman, Matthew W.
A1  - Dedoussis, George V.
A1  - Moreno, Luis A.
A1  - Pedersen, Oluf
A1  - Saarinen, Maiju
A1  - Mohlke, Karen L.
A1  - Boomsma, Dorret I.
A1  - Saw, Seang-Mei
A1  - Lakka, Timo A.
A1  - Koerner, Antje
A1  - Loos, Ruth J. F.
A1  - Ong, Ken K.
A1  - Vollenweider, Peter
A1  - van Duijn, Cornelia M.
A1  - Koppelman, Gerard H.
A1  - Hattersley, Andrew T.
A1  - Holloway, John W.
A1  - Hocher, Berthold
A1  - Heinrich, Joachim
A1  - Power, Chris
A1  - Melbye, Mads
A1  - Guxens, Monica
A1  - Pennell, Craig E.
A1  - Bonnelykke, Klaus
A1  - Bisgaard, Hans
A1  - Eriksson, Johan G.
A1  - Widen, Elisabeth
A1  - Hakonarson, Hakon
A1  - Uitterlinden, Andre G.
A1  - Pouta, Anneli
A1  - Lawlor, Debbie A.
A1  - Smith, George Davey
A1  - Frayling, Timothy M.
A1  - McCarthy, Mark I.
A1  - Grant, Struan F. A.
A1  - Jaddoe, Vincent W. V.
A1  - Jarvelin, Marjo-Riitta
A1  - Timpson, Nicholas J.
A1  - Prokopenko, Inga
A1  - Freathy, Rachel M.
T1  - New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
JF  - Nature genetics
N2  - Birth weight within the normal range is associated with a variety of adult-onset diseases, but the mechanisms behind these associations are poorly understood(1). Previous genome-wide association studies of birth weight identified a variant in the ADCY5 gene associated both with birth weight and type 2 diabetes and a second variant, near CCNL1, with no obvious link to adult traits(2). In an expanded genome-wide association metaanalysis and follow-up study of birth weight (of up to 69,308 individuals of European descent from 43 studies), we have now extended the number of loci associated at genome-wide significance to 7, accounting for a similar proportion of variance as maternal smoking. Five of the loci are known to be associated with other phenotypes: ADCY5 and CDKAL1 with type 2 diabetes, ADRB1 with adult blood pressure and HMGA2 and LCORL with adult height. Our findings highlight genetic links between fetal growth and postnatal growth and metabolism.
Y1  - 2013
U6  - https://doi.org/10.1038/ng.2477
SN  - 1061-4036
VL  - 45
IS  - 1
SP  - 76
EP  - U115
PB  - Nature Publ. Group
CY  - New York
ER  - 
TY  - JOUR
A1  - Beaulieu, Jean-Philippe
A1  - Bennett, David P.
A1  - Fouqué, Pascal
A1  - Williams, Andrew
A1  - Dominik, Martin
A1  - Jorgensen, Uffe Grae
A1  - Kubas, Daniel
A1  - Cassan, Arnaud
A1  - Coutures, Christian
A1  - Greenhill, John
A1  - Hill, Kym
A1  - Menzies, John
A1  - Sackett, Penny D.
A1  - Albrow, Michael D.
A1  - Brillant, Stephane
A1  - Caldwell, John A. R.
A1  - Calitz, Johannes Jacobus
A1  - Cook, Kem H.
A1  - Corrales Cosmeli, Esperanza de Santa Cecilia
A1  - Desort, Morgan
A1  - Dieters, Stefan
A1  - Dominis, Dijana
A1  - Donatowicz, Jadzia
A1  - Hoffman, Martie
A1  - Kane, Stephen R.
A1  - Marquette, Jean-Baptiste
A1  - Martin, Ralph
A1  - Meintjes, Pieter
A1  - Pollard, Karen R.
A1  - Sahu, Kailash C.
A1  - Vinter, Christian
A1  - Wambsganss, Joachim
A1  - Woller, Kristian
A1  - Horne, Keith
A1  - Steele, Iain
A1  - Bramich, Daniel M.
A1  - Burgdorf, Martin
A1  - Snodgrass, Colin
A1  - Bode, Mike
A1  - Udalski, Andr
T1  - Discovery of a cool planet of 5.5 Earth masses through gravitational microlensing
N2  - In the favoured core-accretion model of formation of planetary systems, solid planetesimals accumulate to build up planetary cores, which then accrete nebular gas if they are sufficiently massive. Around M-dwarf stars ( the most common stars in our Galaxy), this model favours the formation of Earth-mass (M+) to Neptune-mass planets with orbital radii of 1 to 10 astronomical units (AU), which is consistent with the small number of gas giant planets known to orbit M-dwarf host stars(1-4). More than 170 extrasolar planets have been discovered with a wide range of masses and orbital periods, but planets of Neptune's mass or less have not hitherto been detected at separations of more than 0.15 AU from normal stars. Here we report the discovery of a 5.5(-2.7)(+5.5)M(+) planetary companion at a separation of 2.6(- 0.6)(+1.5) AU from a 0.22(-0.11)(+0.21)M(.) M-dwarf star, where M-. refers to a solar mass. (We propose to name it OGLE- 2005-BLG-390Lb, indicating a planetary mass companion to the lens star of the microlensing event.) The mass is lower than that of GJ876d (ref. 5), although the error bars overlap. Our detection suggests that such cool, sub-Neptune-mass planets may be more common than gas giant planets, as predicted by the core accretion theory.
Y1  - 2006
UR  - http://www.nature.com/nature/
U6  - https://doi.org/10.1038/Nature04441
SN  - 0028-0836
ER  - 
TY  - JOUR
A1  - Steffen, Will
A1  - Röckstrom, Johan
A1  - Richardson, Katherine
A1  - Lenton, Timothy M.
A1  - Folke, Carl
A1  - Liverman, Diana
A1  - Summerhayes, Colin P.
A1  - Barnosky, Anthony D.
A1  - Cornell, Sarah E.
A1  - Crucifix, Michel
A1  - Donges, Jonathan
A1  - Fetzer, Ingo
A1  - Lade, Steven J.
A1  - Scheffer, Marten
A1  - Winkelmann, Ricarda
A1  - Schellnhuber, Hans Joachim
T1  - Trajectories of the Earth System in the Anthropocene
JF  - Proceedings of the National Academy of Sciences of the United States of America
N2  - We explore the risk that self-reinforcing feedbacks could push the Earth System toward a planetary threshold that, if crossed, could prevent stabilization of the climate at intermediate temperature rises and cause continued warming on a "Hothouse Earth" pathway even as human emissions are reduced. Crossing the threshold would lead to a much higher global average temperature than any interglacial in the past 1.2 million years and to sea levels significantly higher than at any time in the Holocene. We examine the evidence that such a threshold might exist and where it might be. If the threshold is crossed, the resulting trajectory would likely cause serious disruptions to ecosystems, society, and economies. Collective human action is required to steer the Earth System away from a potential threshold and stabilize it in a habitable interglacial-like state. Such action entails stewardship of the entire Earth System-biosphere, climate, and societies-and could include decarbonization of the global economy, enhancement of biosphere carbon sinks, behavioral changes, technological innovations, new governance arrangements, and transformed social values.
KW  - Earth System trajectories
KW  - climate change
KW  - Anthropocene
KW  - biosphere feedbacks
KW  - tipping elements
Y1  - 2018
U6  - https://doi.org/10.1073/pnas.1810141115
SN  - 0027-8424
VL  - 115
IS  - 33
SP  - 8252
EP  - 8259
PB  - National Acad. of Sciences
CY  - Washington
ER  -