TY - JOUR A1 - Groop, Per-Henrik A1 - Cooper, Mark E. A1 - Perkovic, Vlado A1 - Hocher, Berthold A1 - Kanasaki, Keizo A1 - Haneda, Masakazu A1 - Schernthaner, Guntram A1 - Sharma, Kumar A1 - Stanton, Robert C. A1 - Toto, Robert A1 - Cescutti, Jessica A1 - Gordat, Maud A1 - Meinicke, Thomas A1 - Koitka-Weber, Audrey A1 - Thiemann, Sandra A1 - von Eynatten, Maximilian T1 - Linagliptin and its effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction BT - the randomized MARLINA-T2D trial JF - Diabetes obesity & metabolism : a journal of pharmacology and therapeutics N2 - Aims: The MARLINA-T2D study (ClinicalTrials. gov, NCT01792518) was designed to investigate the glycaemic and renal effects of linagliptin added to standard-of-care in individuals with type 2 diabetes and albuminuria. Methods: A total of 360 individuals with type 2 diabetes, HbA1c 6.5% to 10.0% (48-86 mmol/ mol), estimated glomerular filtration rate (eGFR) >= 30 mL/min/1.73 m(2) and urinary albumin-tocreatinine ratio (UACR) 30-3000 mg/g despite single agent renin-angiotensin-system blockade were randomized to double-blind linagliptin (n = 182) or placebo (n = 178) for 24 weeks. The primary and key secondary endpoints were change from baseline in HbA1c at week 24 and time-weighted average of percentage change from baseline in UACR over 24 weeks, respectively. Results: Baseline mean HbA1c and geometric mean (gMean) UACR were 7.8% +/- 0.9% (62.2 +/- 9.6 mmol/mol) and 126 mg/g, respectively; 73.7% and 20.3% of participants had microalbuminuria or macroalbuminuria, respectively. After 24 weeks, the placebo-adjusted mean change in HbA1c from baseline was -0.60% (-6.6 mmol/mol) (95% confidence interval [CI], -0.78 to -0.43 [-8.5 to -4.7 mmol/mol]; P <.0001). The placebo-adjusted gMean for time-weighted average of percentage change in UACR from baseline was -6.0% (95% CI, -15.0 to 3.0; P =.1954). The adverse-event profile, including renal safety and change in eGFR, was similar between the linagliptin and placebo groups. Conclusions: In individuals at early stages of diabetic kidney disease, linagliptin significantly improved glycaemic control but did not significantly lower albuminuria. There was no significant change in placebo-adjusted eGFR. Detection of clinically relevant renal effects of linagliptin may require longer treatment, as its main experimental effects in animal studies have been to reduce interstitial fibrosis rather than alter glomerular haemodynamics. KW - antidiabetic drug KW - clinical trial KW - diabetic nephropathy KW - DPP-IV inhibitor KW - glycaemic control KW - linagliptin Y1 - 2017 U6 - https://doi.org/10.1111/dom.13041 SN - 1462-8902 SN - 1463-1326 VL - 19 IS - 11 SP - 1610 EP - 1619 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Rach, Oliver A1 - Engels, S. A1 - Kahmen, A. A1 - Brauer, Achim A1 - Martin-Puertas, C. A1 - van Geel, B. A1 - Sachse, Dirk T1 - Hydrological and ecological changes in western Europe between 3200 and 2000 years BP derived from lipid biomarker delta D values in lake Meerfelder Maar sediments JF - Quaternary science reviews : the international multidisciplinary research and review journal N2 - One of the most significant Late Holocene climate shifts occurred around 2800 years ago, when cooler and wetter climate conditions established in western Europe. This shift coincided with an abrupt change in regional atmospheric circulation between 2760 and 2560 cal years BP, which has been linked to a grand solar minimum with the same duration (the Homeric Minimum). We investigated the temporal sequence of hydroclimatic and vegetation changes across this interval of climatic change (Homeric climate oscillation) by using lipid biomarker stable hydrogen isotope ratios (ED values) and pollen assemblages from the annually-laminated sediment record from lake Meerfelder Maar (Germany). Over the investigated interval (3200-2000 varve years BP), terrestrial lipid biomarker ED showed a gradual trend to more negative values, consistent with the western Europe long-term climate trend of the Late Holocene. At ca. 2640 varve years BP we identified a strong increase in aquatic plants and algal remains, indicating a rapid change in the aquatic ecosystem superimposed on this long-term trend. Interestingly, this aquatic ecosystem change was accompanied by large changes in ED values of aquatic lipid biomarkers, such as nC(21) and nC(23) (by between 22 and 30%(0)). As these variations cannot solely be explained by hydroclimate changes, we suggest that these changes in the Wag value were influenced by changes in n-alkane source organisms. Our results illustrate that if ubiquitous aquatic lipid biomarkers are derived from a limited pool of organisms, changes in lake ecology can be a driving factor for variations on sedimentary lipid MN values, which then could be easily misinterpreted in terms of hydro climatic changes. (C) 2017 Elsevier Ltd. All rights reserved. KW - Holocene KW - Climate dynamics KW - Paleoclimatology KW - Western Europe KW - Continental biomarkers KW - Organic geochemistry KW - Stable isotopes KW - Vegetation dynamics Y1 - 2017 U6 - https://doi.org/10.1016/j.quascirev.2017.07.019 SN - 0277-3791 VL - 172 SP - 44 EP - 54 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Schütze, Franziska A1 - Fürst, Steffen A1 - Mielke, Jahel A1 - Steudle, Gesine A. A1 - Wolf, Sarah A1 - Jäger, Carlo C. T1 - The Role of Sustainable Investment in Climate Policy JF - Sustainability N2 - Reaching the Sustainable Development Goals requires a fundamental socio-economic transformation accompanied by substantial investment in low-carbon infrastructure. Such a sustainability transition represents a non-marginal change, driven by behavioral factors and systemic interactions. However, typical economic models used to assess a sustainability transition focus on marginal changes around a local optimum, whichby constructionlead to negative effects. Thus, these models do not allow evaluating a sustainability transition that might have substantial positive effects. This paper examines which mechanisms need to be included in a standard computable general equilibrium model to overcome these limitations and to give a more comprehensive view of the effects of climate change mitigation. Simulation results show that, given an ambitious greenhouse gas emission constraint and a price of carbon, positive economic effects are possible if (1) technical progress results (partly) endogenously from the model and (2) a policy intervention triggering an increase of investment is introduced. Additionally, if (3) the investment behavior of firms is influenced by their sales expectations, the effects are amplified. The results provide suggestions for policy-makers, because the outcome indicates that investment-oriented climate policies can lead to more desirable outcomes in economic, social and environmental terms. KW - climate policy KW - green growth KW - macroeconomic models KW - sustainable investment KW - technical progress KW - expectations KW - 1.5 degrees C Y1 - 2017 U6 - https://doi.org/10.3390/su9122221 SN - 2071-1050 VL - 9 PB - MDPI CY - Basel ER - TY - JOUR A1 - García-Camacho, Raúl A1 - Metz, Johannes A1 - Bilton, Mark C. A1 - Tielboerger, Katja T1 - Phylogenetic structure of annual plant communities along an aridity gradient BT - Interacting effects of habitat filtering and shifting plant-plant interactions JF - Israel Journal of Plant Sciences N2 - The phylogenetic structure of communities (PSC) reveals how evolutionary history affects community assembly processes. However, there are important knowledge gaps on PSC patterns for annual communities and there is a need for studies along environmental gradients in dry ecosystems where several processes shape PSC. Here, we investigated the PSC of annual plants along an aridity gradient in Israel, including eight years, two spatial scales, the effects of shrubs on understory, and the phylogenetic signal of important traits. Increasing drought stress led to overdispersed PSC at the drier end of the gradient, indicating that species were less related than expected by chance. This was supported at a smaller spatial scale, where within the drier sites, communities in open- more arid- habitats were more overdispersed than those under nurse shrubs. Interestingly, some key traits related to drought resistance were not conserved in the phylogeny. Together, our findings suggested that while habitat filtering selected for drought resistance strategies, these strategies evolved independently along multiple contrasting evolutionary lineages. Our comprehensive PSC study provides strong evidence for the interacting effects of habitat filtering and plant- plant interactions, particularly highlighting that the conservative evolution of traits should not be assumed in future interpretations of PSC patterns. KW - Annuals KW - aridity gradient KW - community assembly rules KW - community phylogenetics KW - stress-gradient hypothesis KW - trait phylogenetic conservatism Y1 - 2017 U6 - https://doi.org/10.1080/07929978.2017.1288477 SN - 0792-9978 SN - 2223-8980 VL - 64 IS - 1-2 SP - 122 EP - 134 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Dominguez, Marisol A1 - Tiedemann, Ralph A1 - Reboreda, Juan C. A1 - Segura, Luciano A1 - Tittarelli, Fabian A1 - Mahler, Bettina T1 - Genetic structure reveals management units for the yellow cardinal (Gubernatrix cristata), endangered by habitat loss and illegal trapping JF - Conservation genetics KW - Genetic structure KW - Gubernatrix cristata KW - Management units KW - MtDNA KW - Microsatellites KW - Hybrids Y1 - 2017 U6 - https://doi.org/10.1007/s10592-017-0964-4 SN - 1566-0621 SN - 1572-9737 VL - 18 SP - 1131 EP - 1140 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Morf, Carolyn C. A1 - Schurch, Eva A1 - Kufener, Albrecht A1 - Siegrist, Philip A1 - Vater, Aline A1 - Back, Mitja A1 - Mestel, Robert A1 - Schröder-Abe, Michela T1 - Expanding the Nomological Net of the Pathological Narcissism Inventory: German Validation and Extension in a Clinical Inpatient Sample JF - Assessment KW - narcissism KW - assessment KW - Pathological Narcissism Inventory KW - construct validity KW - nomological network Y1 - 2017 U6 - https://doi.org/10.1177/1073191115627010 SN - 1073-1911 SN - 1552-3489 VL - 24 SP - 419 EP - 443 PB - Sage Publ. CY - Thousand Oaks ER - TY - GEN A1 - Schütze, Franziska A1 - Fürst, Steffen A1 - Mielke, Jahel A1 - Steudle, Gesine A. A1 - Wolf, Sarah A1 - Jäger, Carlo C. T1 - The Role of Sustainable Investment in Climate Policy T2 - Postprints der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe N2 - Reaching the Sustainable Development Goals requires a fundamental socio-economic transformation accompanied by substantial investment in low-carbon infrastructure. Such a sustainability transition represents a non-marginal change, driven by behavioral factors and systemic interactions. However, typical economic models used to assess a sustainability transition focus on marginal changes around a local optimum, whichby constructionlead to negative effects. Thus, these models do not allow evaluating a sustainability transition that might have substantial positive effects. This paper examines which mechanisms need to be included in a standard computable general equilibrium model to overcome these limitations and to give a more comprehensive view of the effects of climate change mitigation. Simulation results show that, given an ambitious greenhouse gas emission constraint and a price of carbon, positive economic effects are possible if (1) technical progress results (partly) endogenously from the model and (2) a policy intervention triggering an increase of investment is introduced. Additionally, if (3) the investment behavior of firms is influenced by their sales expectations, the effects are amplified. The results provide suggestions for policy-makers, because the outcome indicates that investment-oriented climate policies can lead to more desirable outcomes in economic, social and environmental terms. T3 - Zweitveröffentlichungen der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe - 137 KW - climate policy KW - green growth KW - macroeconomic models KW - sustainable investment KW - technical progress KW - expectations KW - 1.5 degrees C Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-470485 SN - 1867-5808 IS - 137 ER - TY - JOUR A1 - Estendorfer, Jennifer A1 - Stempfhuber, Barbara A1 - Haury, Paula A1 - Vestergaard, Gisle A1 - Rillig, Matthias C. A1 - Joshi, Jasmin Radha A1 - Schröder, Peter A1 - Schloter, Michael T1 - The Influence of Land Use Intensity on the Plant-Associated Microbiome of Dactylis glomerata L. JF - Frontiers in plant science N2 - In this study, we investigated the impact of different land use intensities (LUI) on the root-associated microbiome of Dactylis glomerata (orchardgrass). For this purpose, eight sampling sites with different land use intensity levels but comparable soil properties were selected in the southwest of Germany. Experimental plots covered land use levels from natural grassland up to intensively managed meadows. We used 16S rRNA gene based barcoding to assess the plant-associated community structure in the endosphere, rhizosphere and bulk soil of D. glomerata. Samples were taken at the reproductive stage of the plant in early summer. Our data indicated that roots harbor a distinct bacterial community, which clearly differed from the microbiome of the rhizosphere and bulk soil. Our results revealed Pseudomonadaceae, Enterobacteriaceae and Comamonadaceae as the most abundant endophytes independently of land use intensity. Rhizosphere and bulk soil were dominated also by Proteobacteria, but the most abundant families differed from those obtained from root samples. In the soil, the effect of land use intensity was more pronounced compared to root endophytes leading to a clearly distinct pattern of bacterial communities under different LUI from rhizosphere and bulk soil vs. endophytes. Overall, a change of community structure on the plant-soil interface was observed, as the number of shared OTUs between all three compartments investigated increased with decreasing land use intensity. Thus, our findings suggest a stronger interaction of the plant with its surrounding soil under low land use intensity. Furthermore, the amount and quality of available nitrogen was identified as a major driver for shifts in the microbiome structure in all compartments. KW - Dactylis glomerata KW - land use change KW - endophytes KW - rhizosphere KW - soil microbiome KW - biodiversity Y1 - 2017 U6 - https://doi.org/10.3389/fpls.2017.00930 SN - 1664-462X VL - 8 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Ahnen, M. L. A1 - Ansoldi, S. A1 - Antonelli, L. A. A1 - Antoranz, P. A1 - Babic, A. A1 - Banerjee, B. A1 - Bangale, P. A1 - de Almeida, U. Barres A1 - Barrio, J. A. A1 - Gonzalez, J. Becerra A1 - Bednarek, W. A1 - Bernardini, E. A1 - Berti, A. A1 - Biasuzzi, B. A1 - Biland, A. A1 - Blanch, O. A1 - Bonnefoy, S. A1 - Bonnoli, G. A1 - Borracci, F. A1 - Bretz, T. A1 - Buson, S. A1 - Carosi, A. A1 - Chatterjee, A. A1 - Clavero, R. A1 - Colin, P. A1 - Colombo, E. A1 - Contreras, J. L. A1 - Cortina, J. A1 - Covino, S. A1 - Da Vela, P. A1 - Dazzi, F. A1 - De Angelis, A. A1 - De Lotto, B. A1 - Wilhelmi, E. de Ona A1 - Di Pierro, F. A1 - Doert, M. A1 - Dominguez, A. A1 - Prester, D. Dominis A1 - Dorner, D. A1 - Doro, M. A1 - Einecke, S. A1 - Glawion, D. Eisenacher A1 - Elsaesser, D. A1 - Engelkemeier, M. A1 - Ramazani, V. Fallah A1 - Fernandez-Barral, A. A1 - Fidalgo, D. A1 - Fonseca, M. V. A1 - Font, L. A1 - Frantzen, K. A1 - Fruck, C. A1 - Galindo, D. A1 - Lopez, R. J. Garcia A1 - Garczarczyk, M. A1 - Terrats, D. Garrido A1 - Gaug, M. A1 - Giammaria, P. A1 - Godinovic, N. A1 - Gonzalez Munoz, A. A1 - Gora, D. A1 - Guberman, D. A1 - Hadasch, D. A1 - Hahn, A. A1 - Hanabata, Y. A1 - Hayashida, M. A1 - Herrera, J. A1 - Hose, J. A1 - Hrupec, D. A1 - Hughes, G. A1 - Idec, W. A1 - Kodani, K. A1 - Konno, Y. A1 - Kubo, H. A1 - Kushida, J. A1 - La Barbera, A. A1 - Lelas, D. A1 - Lindfors, E. A1 - Lombardi, S. A1 - Longo, F. A1 - Lopez, M. A1 - Lopez-Coto, R. A1 - Majumdar, P. A1 - Makariev, M. A1 - Mallot, K. A1 - Maneva, G. A1 - Manganaro, M. A1 - Mannheim, K. A1 - Maraschi, L. A1 - Marcote, B. A1 - Mariotti, M. A1 - Martinez, M. A1 - Mazin, D. A1 - Menzel, U. A1 - Miranda, J. M. A1 - Mirzoyan, R. A1 - Moralejo, A. A1 - Moretti, E. A1 - Nakajima, D. A1 - Neustroev, V. A1 - Niedzwiecki, A. A1 - Rosillo, M. Nievas A1 - Nilsson, K. A1 - Nishijima, K. A1 - Noda, K. A1 - Nogues, L. A1 - Overkemping, A. A1 - Paiano, S. A1 - Palacio, J. A1 - Palatiello, M. A1 - Paneque, D. A1 - Paoletti, R. A1 - Paredes, J. M. A1 - Paredes-Fortuny, X. A1 - Pedaletti, G. A1 - Peresano, M. A1 - Perri, L. A1 - Persic, M. A1 - Poutanen, J. A1 - Moroni, P. G. Prada A1 - Prandini, E. A1 - Puljak, I. A1 - Reichardt, I. A1 - Rhode, W. A1 - Ribo, M. A1 - Rico, J. A1 - Rodriguez Garcia, J. A1 - Saito, T. A1 - Satalecka, K. A1 - Schroder, S. A1 - Schultz, C. A1 - Schweizer, T. A1 - Shore, S. N. A1 - Sillanpaa, A. A1 - Sitarek, J. A1 - Snidaric, I. A1 - Sobczynska, D. A1 - Stamerra, A. A1 - Steinbring, T. A1 - Strzys, M. A1 - Suric, T. A1 - Takalo, L. A1 - Tavecchio, F. A1 - Temnikov, P. A1 - Terzic, T. A1 - Tescaro, D. A1 - Teshima, M. A1 - Thaele, J. A1 - Torres, D. F. A1 - Toyama, T. A1 - Treves, A. A1 - Vanzo, G. A1 - Verguilov, V. A1 - Vovk, I. A1 - Ward, J. E. A1 - Will, M. A1 - Wu, M. H. A1 - Zanin, R. A1 - Abeysekara, A. U. A1 - Archambault, S. A1 - Archer, A. A1 - Benbow, W. A1 - Bird, R. A1 - Buchovecky, M. A1 - Buckley, J. H. A1 - Bugaev, V. A1 - Connolly, M. P. A1 - Cui, W. A1 - Dickinson, H. J. A1 - Falcone, A. A1 - Feng, Q. A1 - Finley, J. P. A1 - Fleischhack, H. A1 - Flinders, A. A1 - Fortson, L. A1 - Gillanders, G. H. A1 - Griffin, S. A1 - Grube, J. A1 - Huetten, M. A1 - Hanna, D. A1 - Holder, J. A1 - Humensky, T. B. A1 - Kaaret, P. A1 - Kar, P. A1 - Kelley-Hoskins, N. A1 - Kertzman, M. A1 - Kieda, D. A1 - Krause, M. A1 - Krennrich, F. A1 - Lang, M. J. A1 - Maier, G. A1 - McCann, A. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Nieto, D. A1 - Ong, R. A. A1 - Otte, N. A1 - Park, N. A1 - Perkins, J. A1 - Pichel, A. A1 - Pohl, M. A1 - Popkow, A. A1 - Pueschel, Elisa A1 - Quinn, J. A1 - Ragan, K. A1 - Reynolds, P. T. A1 - Richards, G. T. A1 - Roache, E. A1 - Rovero, A. C. A1 - Rulten, C. A1 - Sadeh, I. A1 - Santander, M. A1 - Sembroski, G. H. A1 - Shahinyan, K. A1 - Telezhinsky, Igor O. A1 - Tucci, J. V. A1 - Tyler, J. A1 - Wakely, S. P. A1 - Weinstein, A. A1 - Wilcox, P. A1 - Wilhelm, Alina A1 - Williams, D. A. A1 - Zitzer, B. A1 - Razzaque, S. A1 - Villata, M. A1 - Raiteri, C. M. A1 - Aller, H. D. A1 - Aller, M. F. A1 - Larionov, V. M. A1 - Arkharov, A. A. A1 - Blinov, D. A. A1 - Efimova, N. V. A1 - Grishina, T. S. A1 - Hagen-Thorn, V. A. A1 - Kopatskaya, E. N. A1 - Larionova, L. V. A1 - Larionova, E. G. A1 - Morozova, D. A. A1 - Troitsky, I. S. A1 - Ligustri, R. A1 - Calcidese, P. A1 - Berdyugin, A. A1 - Kurtanidze, O. M. A1 - Nikolashvili, M. G. A1 - Kimeridze, G. N. A1 - Sigua, L. A. A1 - Kurtanidze, S. O. A1 - Chigladze, R. A. A1 - Chen, W. P. A1 - Koptelova, E. A1 - Sakamoto, T. A1 - Sadun, A. C. A1 - Moody, J. W. A1 - Pace, C. A1 - Pearson, R. A1 - Yatsu, Y. A1 - Mori, Y. A1 - Carraminyana, A. A1 - Carrasco, L. A1 - de la Fuente, E. A1 - Norris, J. P. A1 - Smith, P. S. A1 - Wehrle, A. A1 - Gurwell, M. A. A1 - Zook, A. A1 - Pagani, C. A1 - Perri, M. A1 - Capalbi, M. A1 - Cesarini, A. A1 - Krimm, H. A. A1 - Kovalev, Y. Y. A1 - Kovalev, Yu. A. A1 - Ros, E. A1 - Pushkarev, A. B. A1 - Lister, M. L. A1 - Sokolovsky, K. V. A1 - Kadler, M. A1 - Piner, G. A1 - Lahteenmaki, A. A1 - Tornikoski, M. A1 - Angelakis, E. A1 - Krichbaum, T. P. A1 - Nestoras, I. A1 - Fuhrmann, L. A1 - Zensus, J. A. A1 - Cassaro, P. A1 - Orlati, A. A1 - Maccaferri, G. A1 - Leto, P. A1 - Giroletti, M. A1 - Richards, J. L. A1 - Max-Moerbeck, W. A1 - Readhead, A. C. S. T1 - Multiband variability studies and novel broadband SED modeling of Mrk 501 in 2009 JF - Astronomy and astrophysics : an international weekly journal N2 - Aims. We present an extensive study of the BL Lac object Mrk 501 based on a data set collected during the multi-instrument campaign spanning from 2009 March 15 to 2009 August 1, which includes, among other instruments, MAGIC, VERITAS, Whipple 10 m, and Fermi-LAT to cover the gamma-ray range from 0.1 GeV to 20 TeV; RXTE and Swift to cover wavelengths from UV to hard X-rays; and GASP-WEBT, which provides coverage of radio and optical wavelengths. Optical polarization measurements were provided for a fraction of the campaign by the Steward and St. Petersburg observatories. We evaluate the variability of the source and interband correlations, the gamma-ray flaring activity occurring in May 2009, and interpret the results within two synchrotron self-Compton (SSC) scenarios. Methods. The multiband variability observed during the full campaign is addressed in terms of the fractional variability, and the possible correlations are studied by calculating the discrete correlation function for each pair of energy bands where the significance was evaluated with dedicated Monte Carlo simulations. The space of SSC model parameters is probed following a dedicated grid-scan strategy, allowing for a wide range of models to be tested and offering a study of the degeneracy of model-to-data agreement in the individual model parameters, hence providing a less biased interpretation than the "single-curve SSC model adjustment" typically reported in the literature. Results. We find an increase in the fractional variability with energy, while no significant interband correlations of flux changes are found on the basis of the acquired data set. The SSC model grid-scan shows that the flaring activity around May 22 cannot be modeled adequately with a one-zone SSC scenario (using an electron energy distribution with two breaks), while it can be suitably described within a two (independent) zone SSC scenario. Here, one zone is responsible for the quiescent emission from the averaged 4.5-month observing period, while the other one, which is spatially separated from the first, dominates the flaring emission occurring at X-rays and very-high-energy (> 100 GeV, VHE) gamma-rays. The flaring activity from May 1, which coincides with a rotation of the electric vector polarization angle (EVPA), cannot be satisfactorily reproduced by either a one-zone or a two-independent-zone SSC model, yet this is partially affected by the lack of strictly simultaneous observations and the presence of large flux changes on sub-hour timescales (detected at VHE gamma rays). Conclusions. The higher variability in the VHE emission and lack of correlation with the X-ray emission indicate that, at least during the 4.5-month observing campaign in 2009, the highest energy (and most variable) electrons that are responsible for the VHE gamma rays do not make a dominant contribution to the similar to 1 keV emission. Alternatively, there could be a very variable component contributing to the VHE gamma-ray emission in addition to that coming from the SSC scenario. The studies with our dedicated SSC grid-scan show that there is some degeneracy in both the one-zone and the two-zone SSC scenarios probed, with several combinations of model parameters yielding a similar model-to-data agreement, and some parameters better constrained than others. The observed gamma-ray flaring activity, with the EVPA rotation coincident with the first gamma-ray flare, resembles those reported previously for low frequency peaked blazars, hence suggesting that there are many similarities in the flaring mechanisms of blazars with different jet properties. KW - BL Lacertae objects: individual: Markarian 501 KW - methods: data analysis Y1 - 2017 U6 - https://doi.org/10.1051/0004-6361/201629540 SN - 1432-0746 VL - 603 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Archambault, S. A1 - Archer, A. A1 - Benbow, W. A1 - Bird, R. A1 - Bourbeau, E. A1 - Brantseg, T. A1 - Buchovecky, M. A1 - Buckley, J. H. A1 - Bugaev, V. A1 - Byrum, K. A1 - Cerruti, M. A1 - Christiansen, J. L. A1 - Connolly, M. P. A1 - Cui, W. A1 - Daniel, M. K. A1 - Feng, Q. A1 - Finley, J. P. A1 - Fleischhack, H. A1 - Fortson, L. A1 - Furniss, A. A1 - Geringer-Sameth, A. A1 - Griffin, S. A1 - Grube, J. A1 - Hütten, M. A1 - Hakansson, N. A1 - Hanna, D. A1 - Hervet, O. A1 - Holder, J. A1 - Hughes, G. A1 - Hummensky, B. A1 - Johnson, C. A. A1 - Kaaret, P. A1 - Kar, P. A1 - Kelley-Hoskins, N. A1 - Kertzman, M. A1 - Kieda, D. A1 - Koushiappas, S. A1 - Krause, M. A1 - Krennrich, F. A1 - Lang, M. J. A1 - Lin, T. T. Y. A1 - McArthur, S. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Nieto, D. A1 - Ong, R. A. A1 - Otte, A. N. A1 - Park, N. A1 - Pohl, M. A1 - Popkow, A. A1 - Pueschel, Elisa A1 - Quinn, J. A1 - Ragan, K. A1 - Reynolds, P. T. A1 - Richards, G. T. A1 - Roache, E. A1 - Rulten, C. A1 - Sadeh, I. A1 - Santander, M. A1 - Sembroski, G. H. A1 - Shahinyan, K. A1 - Smith, A. W. A1 - Staszak, D. A1 - Telezhinsky, Igor O. A1 - Trepanier, S. A1 - Tucci, J. V. A1 - Tyler, J. A1 - Wakely, S. P. A1 - Weinstein, A. A1 - Wilcox, P. A1 - Williams, D. A. A1 - Zitzer, B. T1 - Dark matter constraints from a joint analysis of dwarf Spheroidal galaxy observations with VERITAS JF - Physical review : D, Particles, fields, gravitation, and cosmology N2 - We present constraints on the annihilation cross section of weakly interacting massive particles dark matter based on the joint statistical analysis of four dwarf galaxies with VERITAS. These results are derived from an optimized photon weighting statistical technique that improves on standard imaging atmospheric Cherenkov telescope (IACT) analyses by utilizing the spectral and spatial properties of individual photon events. We report on the results of similar to 230 hours of observations of five dwarf galaxies and the joint statistical analysis of four of the dwarf galaxies. We find no evidence of gamma-ray emission from any individual dwarf nor in the joint analysis. The derived upper limit on the dark matter annihilation cross section from the joint analysis is 1.35 x 10(-23) cm(3) s(-1) at 1 TeV for the bottom quark (b (b) over bar) final state, 2.85 x 10(-24) cm(3) s(-1) at 1 TeV for the tau lepton (tau+tau(-)) final state and 1.32 x 10-25 cm(3) s(-1) at 1 TeV for the gauge boson (gamma gamma) final state. Y1 - 2017 U6 - https://doi.org/10.1103/PhysRevD.95.082001 SN - 2470-0010 SN - 2470-0029 VL - 95 IS - 8 PB - American Physical Society CY - College Park ER - TY - JOUR A1 - Sirbescu, Mona-Liza C. A1 - Schmidt, Christian A1 - Veksler, Ilya V. A1 - Whittington, Alan G. A1 - Wilke, Max T1 - Experimental crystallization of undercooled felsic liquids BT - generation of pegmatitic texture JF - Journal of petrology N2 - The crystallization kinetics of silicate liquids were studied experimentally in the system haplogranite-B-Li-H2O, at variable degrees of undercooling and variable water concentration. We investigated the kinetics of nucleation and crystallization of unseeded synthetic hydrous haplogranite with 1 wt % Li2O + 2 center dot 3 wt % B2O3 added (composition C1) and 2 wt % Li2O + 4 center dot 6 wt % B2O3 added (composition C2). Compositions C1 and C2 are simplified representative bulk compositions of Li-rich pegmatites and their highly differentiated cores, respectively. Starting water contents varied between 3 and 9 wt %. With few exceptions, the system remained water-undersaturated. About 86 isothermal runs of 1-60 days duration, grouped in 25 time series of constant temperature and initial H2O content, were carried out at temperatures from 400 to 700A degrees C at 300 MPa, corresponding to variable degrees of undercooling between the liquidus and glass transition. Viscosity measurements indicate that the glass transition for both compositions is below 400A degrees C for 3 wt % water and below 300A degrees C for 6 center dot 5 wt % water. The melts remained virtually crystal free at 400A degrees C, about 100A degrees C and 120A degrees C above the glass transition for compositions C1 and C2, respectively, in experiments up to 30 days long. This result is consistent with the existence of low-temperature, undercooled melts in the crust. At lower values of undercooling the runs crystallized partially, up to about 70% volume fraction. Undercooling and the amount of water are the main factors controlling nucleation and growth rates, and therefore textures. Minerals nucleate and grow sequentially according to mineral-specific nucleation delays. The mineral assemblage started with Li-Al stuffed quartz (in C1) and virgilite (in C2), solid-solutions between quartz and gamma-spodumene. The quartz-like phases were typically followed by spherulitic alkali feldspar-quartz intergrowths, euhedral petalite, and fine-grained muscovite. Nearly pure quartz formed as rims and replacement of metastable virgilite and stuffed quartz, in particular at the boron- and water-rich crystallization front of large feldspar or petalite. With the exception of muscovite, all minerals nucleated heterogeneously, on the capsule wall or on pre-existing minerals, and grew inwards, towards the capsule center. Experimental textures resembled the textures of zoned pegmatites, including skeletal, graphic, unidirectional, radiating, spherulitic, massive, and replacement textures. In some cases, when fluid saturation was reached, miarolitic cavities developed containing euhedral crystals. Although unidirectional growth rates appeared to slow down in time, volumetric rates for stable graphic alkali-feldspar quartz intergrowths and petalite remained constant for up to 60 days and similar to 70% crystallization. Metastable stuffed quartz and virgilite diminished in their growth rates in runs of 30 days or longer, were resorbed in the melt, and were partially replaced by second-generation quartz. Unobstructed, self-sustained crystal growth in conditions of very low nucleation density appears to be the dominant mechanism to form giant pegmatitic crystals, although experimental growth rates are much slower than predicted in nature based on conductive-cooling models. KW - experimental petrology KW - lithium pegmatites KW - igneous texture KW - viscosity KW - crystal nucleation KW - crystal growth rate Y1 - 2017 U6 - https://doi.org/10.1093/petrology/egx027 SN - 0022-3530 SN - 1460-2415 VL - 58 IS - 3 SP - 539 EP - 568 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Warren, Donald C. A1 - Ellison, Donald C. A1 - Barkov, Maxim V. A1 - Nagataki, Shigehiro T1 - Nonlinear Particle Acceleration and Thermal Particles in GRB Afterglows JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - The standard model for GRB afterglow emission treats the accelerated electron population as a simple power law, N(E) proportional to E-p for p greater than or similar to 2. However, in standard Fermi shock acceleration, a substantial fraction of the swept-up particles do not enter the acceleration process at all. Additionally, if acceleration is efficient, then the nonlinear back-reaction of accelerated particles on the shock structure modifies the shape of the nonthermal tail of the particle spectra. Both of these modifications to the standard synchrotron afterglow impact the luminosity, spectra, and temporal variation of the afterglow. To examine the effects of including thermal particles and nonlinear particle acceleration on afterglow emission, we follow a hydrodynamical model for an afterglow jet and simulate acceleration at numerous points during the evolution. When thermal particles are included, we find that the electron population is at no time well fitted by a single power law, though the highest-energy electrons are; if the acceleration is efficient, then the power-law region is even smaller. Our model predicts hard-soft-hard spectral evolution at X-ray energies, as well as an uncoupled X-ray and optical light curve. Additionally, we show that including emission from thermal particles has drastic effects (increases by factors of 100 and 30, respectively) on the observed flux at optical and GeV energies. This enhancement of GeV emission makes afterglow detections by future gamma-ray observatories, such as CTA, very likely. KW - acceleration of particles KW - cosmic rays KW - gamma-ray burst: general KW - shock waves KW - turbulence Y1 - 2017 U6 - https://doi.org/10.3847/1538-4357/aa56c3 SN - 0004-637X SN - 1538-4357 VL - 835 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Archambault, S. A1 - Archer, A. A1 - Benbow, W. A1 - Buchovecky, M. A1 - Bugaev, V. A1 - Cerruti, M. A1 - Connolly, M. P. A1 - Cui, W. A1 - Falcone, A. A1 - Alonso, M. Fernandez A1 - Finley, J. P. A1 - Fleischhack, H. A1 - Fortson, L. A1 - Furniss, A. A1 - Griffin, S. A1 - Hutten, M. A1 - Hervet, O. A1 - Holder, J. A1 - Humensky, T. B. A1 - Johnson, C. A. A1 - Kaaret, P. A1 - Kar, P. A1 - Kieda, D. A1 - Krause, M. A1 - Krennrich, F. A1 - Lang, M. J. A1 - Lin, T. T. Y. A1 - Maier, G. A1 - McArthur, S. A1 - Moriarty, P. A1 - Nieto, D. A1 - Ong, R. A. A1 - Otte, A. N. A1 - Pohl, M. A1 - Popkow, A. A1 - Pueschel, Elisa A1 - Quinn, J. A1 - Ragan, K. A1 - Reynolds, P. T. A1 - Richards, G. T. A1 - Roache, E. A1 - Rovero, A. C. A1 - Sadeh, I. A1 - Shahinyan, K. A1 - Staszak, D. A1 - Telezhinsky, Igor O. A1 - Tyler, J. A1 - Wakely, S. P. A1 - Weinstein, A. A1 - Weisgarber, T. A1 - Wilcox, P. A1 - Wilhelm, Alina A1 - Williams, D. A. A1 - Zitzer, B. T1 - Search for Magnetically Broadened Cascade Emission from Blazars with VERITAS JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We present a search for magnetically broadened gamma-ray emission around active galactic nuclei (AGNs), using VERITAS observations of seven hard-spectrum blazars. A cascade process occurs when multi-TeV gamma-rays from an AGN interact with extragalactic background light (EBL) photons to produce electron-positron pairs, which then interact with cosmic microwave background photons via inverse-Compton scattering to produce gamma-rays. Due to the deflection of the electron- positron pairs, a non-zero intergalactic magnetic field (IGMF) would potentially produce detectable effects on the angular distribution of the cascade emission. In particular, an angular broadening compared to the unscattered emission could occur. Through non-detection of angularly broadened emission from 1ES 1218 vertical bar 304, the source with the largest predicted cascade fraction, we exclude a range of IGMF strengths around 10(-14) G at the 95% confidence level. The extent of the exclusion range varies with the assumptions made about the intrinsic spectrum of 1ES. 1218+304 and the EBL model used in the simulation of the cascade process. All of the sources are used to set limits on the flux due to extended emission. KW - BL Lacertae objects: general KW - galaxies: active KW - gamma rays: galaxies KW - magnetic fields Y1 - 2017 U6 - https://doi.org/10.3847/1538-4357/835/2/288 SN - 0004-637X SN - 1538-4357 VL - 835 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Almeida, Leonardo A. A1 - Sana, H. A1 - Taylor, W. A1 - Barbá, Rodolfo A1 - Bonanos, Alceste Z. A1 - Crowther, Paul A1 - Damineli, Augusto A1 - de Koter, A. A1 - de Mink, Selma E. A1 - Evans, C. J. A1 - Gieles, Mark A1 - Grin, Nathan J. A1 - Hénault-Brunet, V. A1 - Langer, Norbert A1 - Lennon, D. A1 - Lockwood, Sean A1 - Maíz Apellániz, Jesús A1 - Moffat, A. F. J. A1 - Neijssel, C. A1 - Norman, C. A1 - Ramírez-Agudelo, O. H. A1 - Richardson, N. D. A1 - Schootemeijer, Abel A1 - Shenar, Tomer A1 - Soszyński, Igor A1 - Tramper, Frank A1 - Vink, J. S. T1 - The tarantula massive binary monitoring BT - I. Observational campaign and OB-type spectroscopic binaries JF - Astronomy and astrophysics : an international weekly journal N2 - Context: Massive binaries play a crucial role in the Universe. Knowing the distributions of their orbital parameters is important for a wide range of topics from stellar feedback to binary evolution channels and from the distribution of supernova types to gravitational wave progenitors, yet no direct measurements exist outside the Milky Way. Aims: The Tarantula Massive Binary Monitoring project was designed to help fill this gap by obtaining multi-epoch radial velocity (RV) monitoring of 102 massive binaries in the 30 Doradus region. Methods: In this paper we analyze 32 FLAMES/GIRAFFE observations of 93 O- and 7 B-type binaries. We performed a Fourier analysis and obtained orbital solutions for 82 systems: 51 single-lined (SB1) and 31 double-lined (SB2) spectroscopic binaries. Results: Overall, the binary fraction and orbital properties across the 30 Doradus region are found to be similar to existing Galactic samples. This indicates that within these domains environmental effects are of second order in shaping the properties of massive binary systems. A small difference is found in the distribution of orbital periods, which is slightly flatter (in log space) in 30 Doradus than in the Galaxy, although this may be compatible within error estimates and differences in the fitting methodology. Also, orbital periods in 30 Doradus can be as short as 1.1 d, somewhat shorter than seen in Galactic samples. Equal mass binaries (q> 0.95) in 30 Doradus are all found outside NGC 2070, the central association that surrounds R136a, the very young and massive cluster at 30 Doradus’s core. Most of the differences, albeit small, are compatible with expectations from binary evolution. One outstanding exception, however, is the fact that earlier spectral types (O2–O7) tend to have shorter orbital periods than later spectral types (O9.2–O9.7). Conclusions: Our results point to a relative universality of the incidence rate of massive binaries and their orbital properties in the metallicity range from solar (Z⊙) to about half solar. This provides the first direct constraints on massive binary properties in massive star-forming galaxies at the Universe’s peak of star formation at redshifts z ~ 1 to 2 which are estimated to have Z ~ 0.5 Z⊙. KW - stars: early-type KW - stars: massive KW - binaries: spectroscopic KW - binaries: close Y1 - 2017 U6 - https://doi.org/10.1051/0004-6361/201629844 SN - 1432-0746 VL - 598 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Simons, Nadja K. A1 - Lewinsohn, Thomas A1 - Bluethgen, Nico A1 - Buscot, Francois A1 - Boch, Steffen A1 - Daniel, Rolf A1 - Gossner, Martin M. A1 - Jung, Kirsten A1 - Kaiser, Kristin A1 - Müller, Jörg A1 - Prati, Daniel A1 - Renner, Swen C. A1 - Socher, Stephanie A. A1 - Sonnemann, Ilja A1 - Weiner, Christiane N. A1 - Werner, Michael A1 - Wubet, Tesfaye A1 - Wurst, Susanne A1 - Weisser, Wolfgang W. T1 - Contrasting effects of grassland management modes on species-abundance distributions of multiple groups JF - Agriculture, ecosystems & environment : an international journal for scientific research on the relationship of agriculture and food production to the biosphere N2 - Intensive land use is a major cause of biodiversity loss, but most studies comparing the response of multiple taxa rely on simple diversity measures while analyses of other community attributes are only recently gaining attention. Species-abundance distributions (SADs) are a community attribute that can be used to study changes in the overall abundance structure of species groups, and whether these changes are driven by abundant or rare species. We evaluated the effect of grassland management intensity for three land-use modes (fertilization, mowing, grazing) and their combination on species richness and SADs for three belowground (arbuscular mycorrhizal fungi, prokaryotes and insect larvae) and seven aboveground groups (vascular plants, bryophytes and lichens; arthropod herbivores; arthropod pollinators; bats and birds). Three descriptors of SADs were evaluated: general shape (abundance decay rate), proportion of rare species (rarity) and proportional abundance of the commonest species (dominance). Across groups, taxonomic richness was largely unaffected by land-use intensity and only decreased with increasing mowing intensity. Of the three SAD descriptors, abundance decay rate became steeper with increasing combined land-use intensity across groups. This reflected a decrease in rarity among plants, herbivores and vertebrates. Effects of fertilization on the three descriptors were similar to the combined land-use intensity effects. Mowing intensity only affected the SAD descriptors of insect larvae and vertebrates, while grazing intensity produced a range of effects on different descriptors in distinct groups. Overall, belowground groups had more even abundance distribtitions than aboveground groups. Strong differences among aboveground groups and between above- and belowground groups indicate that no single taxonomic group can serve as an indicator for effects in other groups. In the past, the use of SADs has been hampered by concerns over theoretical models underlying specific forms of SADs. Our study shows that SAD descriptors that are not connected to a particular model are suitable to assess the effect of land use on community structure. KW - Biodiversity KW - Cutting frequency KW - Management intensity KW - Rank-abundance KW - Species loss KW - Rarity Y1 - 2017 U6 - https://doi.org/10.1016/j.agee.2016.12.022 SN - 0167-8809 SN - 1873-2305 VL - 237 SP - 143 EP - 153 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Rollnik, Jens D. A1 - Adolphsen, Jens A1 - Bauer, J. A1 - Bertram, Maja A1 - Brocke, Jan A1 - Dohmen, Christian A1 - Donauer, E. A1 - Hartwich, Mathias A1 - Heidler, Maria Dorothea A1 - Huge, Volker A1 - Klarmann, Silke A1 - Lorenzl, Stefan A1 - Lück, Michelle A1 - Mertl-Rötzer, Marion A1 - Mokrusch, Thomas A1 - Nowak, D. A. A1 - Platz, Tanja A1 - Riechmann, Lutz A1 - Schlachetzki, Felix A1 - von Helden, Alvin A1 - Wallesch, C. W. A1 - Zergiebel, D. A1 - Pohl, M. T1 - Prolongiertes Weaning in der neurologisch-neurochirurgischen Frührehabilitation JF - Der Nervenarzt: Organ der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde ; Mitteilungsblatt der Deutschen Gesellschaft für Neurologie N2 - Prolonged weaning of patients with neurological or neurosurgery disorders is associated with specific characteristics, which are taken into account by the German Society for Neurorehabilitation (DGNR) in its own guideline. The current S2k guideline of the German Society for Pneumology and Respiratory Medicine is referred to explicitly with regard to definitions (e.g., weaning and weaning failure), weaning categories, pathophysiology of weaning failure, and general weaning strategies. In early neurological and neurosurgery rehabilitation, patients with central of respiratory regulation disturbances (e.g., cerebral stem lesions), swallowing disturbances (neurogenic dysphagia), neuromuscular problems (e.g., critical illness polyneuropathy, Guillain-Barre syndrome, paraplegia, Myasthenia gravis) and/or cognitive disturbances (e.g., disturbed consciousness and vigilance disorders, severe communication disorders), whose care during the weaning of ventilation requires, in addition to intensive medical competence, neurological or neurosurgical and neurorehabilitation expertise. In Germany, this competence is present in centers of early neurological and neurosurgery rehabilitation, as a hospital treatment. The guideline is based on a systematic search of guideline databases and MEDLINE. Consensus was established by means of a nominal group process and Delphi procedure moderated by the Association of the Scientific Medical Societies in Germany (AWMF). In the present guideline of the DGNR, the special structural and substantive characteristics of early neurological and neurosurgery rehabilitation and existing studies on weaning in early rehabilitation facilities are examined. Addressees of the guideline are neurologists, neurosurgeons, anesthesiologists, palliative physicians, speech therapists, intensive care staff, ergotherapists, physiotherapists, and neuropsychologists. In addition, this guideline is intended to provide information to specialists for physical medicine and rehabilitation (PMR), pneumologists, internists, respiratory therapists, the German Medical Service of Health Insurance Funds (MDK) and the German Association of Health Insurance Funds (MDS). The main goal of this guideline is to convey the current knowledge on the subject of "Prolonged weaning in early neurological and neurosurgery rehabilitation". N2 - Das prolongierte Weaning von Patienten mit neurologischen oder neurochirurgischen Erkrankungen weist Besonderheiten auf, denen die Deutsche Gesellschaft für Neurorehabilitation e. V. in einer eigenen Leitlinie Rechnung trägt. Im Hinblick auf Definitionen (z. B. Weaningerfolg und -versagen), Weaningkategorien, Pathophysiologie des Weaningversagens und allgemeine Weaningstrategien wird ausdrücklich auf die aktuelle S2k-Leitlinie der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V. verwiesen. In der neurologisch-neurochirurgischen Frührehabilitation werden Patienten mit zentralen Störungen der Atmungsregulation (z. B. Hirnstammläsionen), des Schluckaktes (neurogene Dysphagien), mit neuromuskulären Problemen (z. B. Critical-illness-Polyneuropathie, Guillain-Barre-Syndrom, Querschnittlähmungen, Myasthenia gravis) und/oder kognitiven Störungen (z. B. Bewusstseins- und Vigilanzstörungen, schwere Kommunikationsstörungen) versorgt, deren Betreuung bei der Entwöhnung von der Beatmung neben intensivmedizinischer Kompetenz auch neurologische bzw. neurochirurgische und neurorehabilitative Expertise erfordert. In Deutschland wird diese Kompetenz in Zentren der neurologisch-neurochirurgischen Frührehabilitation vorgehalten, und zwar als Krankenhausbehandlung. Der Leitlinie liegt eine systematische Recherche von Leitliniendatenbanken und Medline zugrunde. Unter Moderation durch die Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) erfolgte die Konsensfindung mittels nominalen Gruppenprozesses und Delphi-Verfahren. In der vorliegenden Leitlinie der DGNR wird auf die strukturellen und inhaltlichen Besonderheiten der neurologisch-neurochirurgischen Frührehabilitation sowie vorhandene Studien zum Weaning in Frührehabilitationseinrichtungen eingegangen. Adressaten der Leitlinie sind Neurologen, Neurochirurgen, Anästhesisten, Palliativmediziner, Logopäden, Intensivpflegekräfte, Ergotherapeuten, Physiotherapeuten und Neuropsychologen. Ferner richtet sich diese Leitlinie zur Information an Fachärzte für Physikalische Medizin und Rehabilitation (PMR), Pneumologen, Internisten, Atmungstherapeuten, den Medizinischen Dienst der Krankenkassen (MDK) und des Spitzenverbands Bund der Krankenkassen e. V. (MDS). Das wesentliche Ziel dieser Leitlinie ist es, den aktuellen Wissensstand zum Thema „Prolongiertes Weaning in der neurologisch-neurochirurgischen Frührehabilitation“ zu vermitteln. T2 - Prolonged weaning during early neurological and neurosurgical rehabilitation KW - Tracheostomy KW - Neurocognitive disorders KW - Paraplegia KW - Psychological techniques KW - Care techniques KW - Tracheotomie KW - Hirnorganisches Syndrom KW - Querschnittlähmung KW - Psychologische Intervention KW - Pflegerische Techniken Y1 - 2017 U6 - https://doi.org/10.1007/s00115-017-0332-0 SN - 0028-2804 SN - 1433-0407 VL - 88 SP - 652 EP - 674 PB - Springer CY - New York ER - TY - GEN A1 - Kühne, Franziska A1 - Meinders, C. A1 - Mohr, H. A1 - Hafenbrack, K. A1 - Kieseritzky, K. A1 - Rosenberger, C. A1 - Haerter, M. A1 - Schulz-Kindermann, F. A1 - Klinger, R. A1 - Nestoriuc, A. Y. T1 - Psychologische Interventionen zur Schmerzreduktion T1 - Psychological Interventions for Pain Reduction BT - Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der Österreichischen Schmerzgesellschaft und der Deutschen Interdisziplinären Vereinigung für Schmerztherapie T2 - Der Schmerz N2 - Der Leserbrief fokussiert in weiten Teilen auf das Gutachterwesen, weshalb wir ausschließlich auf die inhaltlichen Punkte im Zusammenhang mit unserer Arbeit eingehen. Untersucht wurden schmerzpsychologische Interventionen, wie beschrieben definiert als psychologische Interventionen, deren primäres Ziel die Schmerzreduktion war. Die extrahierten Zielgrößen, wie Lebensqualität oder Depressivität, ergaben sich aus den in den Primärstudien untersuchten Hauptoutcomes und nicht aus der Suchstrategie. Zur Einschätzung der methodischen Qualität der Primärstudien konnte ein Kriterium des von Johannsen und Kollegen [2] gebildeten Scores nicht berücksichtigt werden, da die eingeschlossenen Primärstudien keine metaanalytische Zusammenfassung erlaubten. Stellt man dies in Rechnung, bleibt die Vergleichbarkeit beider Werte erhalten. Die Evidenzsynthese erfolgte narrativ in Text- und Tabellenform, d. h. in Form einer strukturierten Zusammenfassung und Diskussion von Studien [1]. Um unsere Arbeit zu fokussieren, hätten wir eine weitergehende Gegenüberstellung wie auch eine Überprüfung von Zitaten und Übersetzungen selbstverständlich vorgenommen, wenn wir den Hinweis dazu vor Publikation erhalten hätten. Y1 - 2017 U6 - https://doi.org/10.1007/s00482-017-0223-0 SN - 0932-433X SN - 1432-2129 VL - 31 SP - 404 EP - 404 PB - Springer CY - New York ER - TY - JOUR A1 - Paragas, Erickson M. A1 - Humphreys, Sara C. A1 - Min, Joshua A1 - Joswig-Jones, Carolyn A. A1 - Leimkühler, Silke A1 - Jones, Jeffrey P. T1 - ecoAO BT - a simple system for the study of human aldehyde oxidases role in drug metabolism JF - ACS OMEGA N2 - Although aldehyde oxidase (AO) is an important hepatic drug-metabolizing enzyme, it remains understudied and is consequently often overlooked in preclinical studies, an oversight that has resulted in the failure of multiple clinical trials. AO’s preclusion to investigation stems from the following: (1) difficulties synthesizing metabolic standards due to the chemospecificity and regiospecificity of the enzyme and (2) significant inherent variability across existing in vitro systems including liver cytosol, S9 fractions, and primary hepatocytes, which lack specificity and generate discordant expression and activity profiles. Here, we describe a practical bacterial biotransformation system, ecoAO, addressing both issues simultaneously. ecoAO is a cell paste of MoCo-producing Escherichia coli strain TP1017 expressing human AO. It exhibits specific activity toward known substrates, zoniporide, 4-trans-(N,N-dimethylamino)cinnamaldehyde, O6-benzylguanine, and zaleplon; it also has utility as a biocatalyst, yielding milligram quantities of synthetically challenging metabolite standards such as 2-oxo-zoniporide. Moreover, ecoAO enables routine determination of kcat and V/K, which are essential parameters for accurate in vivo clearance predictions. Furthermore, ecoAO has potential as a preclinical in vitro screening tool for AO activity, as demonstrated by its metabolism of 3-aminoquinoline, a previously uncharacterized substrate. ecoAO promises to provide easy access to metabolites with the potential to improve pharmacokinetic clearance predictions and guide drug development. Y1 - 2017 U6 - https://doi.org/10.1021/acsomega.7b01054 SN - 2470-1343 VL - 2 SP - 4820 EP - 4827 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Behrends, Jan C. A1 - Katzer, Nikolaus A1 - Lindenberger, Thomas T1 - 100 Jahre Roter Oktober BT - Versuche zur Historisierung der Russischen Revolution JF - 100 Jahre Roter Oktober : zur Weltgeschichte der russischen Revolution Y1 - 2017 SN - 978-3-7425-0081-6 SP - 9 EP - 27 PB - bpb, Bundeszentrale für politische Bildung CY - Berlin ER - TY - JOUR A1 - Schall, Peter A1 - Gossner, Martin M. A1 - Heinrichs, Steffi A1 - Fischer, Markus A1 - Boch, Steffen A1 - Prati, Daniel A1 - Jung, Kirsten A1 - Baumgartner, Vanessa A1 - Blaser, Stefan A1 - Böhm, Stefan A1 - Buscot, Francois A1 - Daniel, Rolf A1 - Goldmann, Kezia A1 - Kaiser, Kristin A1 - Kahl, Tiemo A1 - Lange, Markus A1 - Müller, Jörg Hans A1 - Overmann, Jörg A1 - Renner, Swen C. A1 - Schulze, Ernst-Detlef A1 - Sikorski, Johannes A1 - Tschapka, Marco A1 - Türke, Manfred A1 - Weisser, Wolfgang W. A1 - Wemheuer, Bernd A1 - Wubet, Tesfaye A1 - Ammer, Christian T1 - The impact of even-aged and uneven-aged forest management on regional biodiversity of multiple taxa in European beech forests JF - Journal of applied ecology : an official journal of the British Ecological Society N2 - 1. For managed temperate forests, conservationists and policymakers favour fine-grained uneven-aged (UEA) management over more traditional coarse-grained even-aged (EA) management, based on the assumption that within-stand habitat heterogeneity enhances biodiversity. There is, however, little empirical evidence to support this assumption. We investigated for the first time how differently grained forest management systems affect the biodiversity of multiple above- and below-ground taxa across spatial scales. 2. We sampled 15 taxa of animals, plants, fungi and bacteria within the largest contiguous beech forest landscape of Germany and classified them into functional groups. Selected forest stands have been managed for more than a century at different spatial grains. The EA (coarse-grained management) and UEA (fine-grained) forests are comparable in spatial arrangement, climate and soil conditions. These were compared to forests of a nearby national park that have been unmanaged for at least 20years. We used diversity accumulation curves to compare -diversity for Hill numbers D-0 (species richness), D-1 (Shannon diversity) and D-2 (Simpson diversity) between the management systems. Beta diversity was quantified as multiple-site dissimilarity. 3. Gamma diversity was higher in EA than in UEA forests for at least one of the three Hill numbers for six taxa (up to 77%), while eight showed no difference. Only bacteria showed the opposite pattern. Higher -diversity in EA forests was also found for forest specialists and saproxylic beetles. 4. Between-stand -diversity was higher in EA than in UEA forests for one-third (all species) and half (forest specialists) of all taxa, driven by environmental heterogeneity between age-classes, while -diversity showed no directional response across taxa or for forest specialists. 5. Synthesis and applications. Comparing EA and uneven-aged forest management in Central European beech forests, our results show that a mosaic of different age-classes is more important for regional biodiversity than high within-stand heterogeneity. We suggest reconsidering the current trend of replacing even-aged management in temperate forests. Instead, the variability of stages and stand structures should be increased to promote landscape-scale biodiversity. KW - beta diversity KW - forest specialists KW - gamma diversity KW - heterogeneity KW - Hill numbers KW - saproxylic beetles KW - spatial grain KW - species accumulation curve KW - species richness KW - species turnover Y1 - 2017 U6 - https://doi.org/10.1111/1365-2664.12950 SN - 0021-8901 SN - 1365-2664 VL - 55 IS - 1 SP - 267 EP - 278 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Julier, Adele C. M. A1 - Jardine, Phillip E. A1 - Adu-Bredu, Stephen A1 - Coe, Angela L. A1 - Duah-Gyamfi, Akwasi A1 - Fraser, Wesley T. A1 - Lomax, Barry H. A1 - Malhi, Yadvinder A1 - Moore, Sam A1 - Owusu-Afriyie, Kennedy A1 - Gosling, William D. T1 - The modern pollen-vegetation relationships of a tropical forest-savannah mosaic landscape, Ghana, West Africa JF - Palynology N2 - Transitions between forest and savannah vegetation types in fossil pollen records are often poorly understood due to over-production by taxa such as Poaceae and a lack of modern pollen-vegetation studies. Here, modern pollen assemblages from within a forest-savannah transition in West Africa are presented and compared, their characteristic taxa discussed, and implications for the fossil record considered. Fifteen artificial pollen traps were deployed for 1 year, to collect pollen rain from three vegetation plots within the forest-savannah transition in Ghana. High percentages of Poaceae and Melastomataceae/Combretaceae were recorded in all three plots. Erythrophleum suaveolens characterised the forest plot, Manilkara obovata the transition plot and Terminalia the savannah plot. The results indicate that Poaceae pollen influx rates provide the best representation of the forest-savannah gradient, and that a Poaceae abundance of >40% should be considered as indicative of savannah-type vegetation in the fossil record. KW - pollen KW - transitions KW - Poaceae KW - savannah KW - Ghana KW - palaeoecology KW - Bosumtwi Y1 - 2017 U6 - https://doi.org/10.1080/01916122.2017.1356392 SN - 0191-6122 SN - 1558-9188 VL - 42 IS - 3 SP - 324 EP - 338 PB - Taylor & Francis Group CY - Philadelphia ER - TY - JOUR A1 - Endrejat, Paul C. A1 - Baumgarten, Franz A1 - Kauffeld, Simone T1 - When theory meets practice BT - Combining Lewin’s Ideas about Change with Motivational Interviewing to Increase Energy-Saving Behaviours Within Organizations JF - Journal of Change Management N2 - Although more than seven decades have passed since Lewin laid the foundation for how employees’ behaviour could be changed within organizations, his ideas are far from being obsolescent. Accordingly, this article demonstrates how Lewin’s concepts can still be of use in tackling current issues (i.e. the need to raise energy-saving behaviours within organizations). In order to revive Lewin’s concepts, we combine his approaches on organization change with Motivational Interviewing (MI), a facilitation approach that fits well with his democratic and participatory mind-set. After a theoretical consideration of how Lewin’s ideas could be accompanied by MI principles, we outline a practical concept for raising the level of employees’ energy-saving behaviours to a higher standard. The usefulness of our concept is highlighted on the basis of qualitative (a force field analysis) and quantitative (an increase of energy-saving norms and – behaviours) data. Lewin’s legacy for current organization development, and the theoretical as well as practical implications for how his ideas could be applied through a combination with MI practices, are discussed. KW - Kurt Lewin KW - field theory KW - group dynamics KW - motivational interviewing KW - energy-saving KW - organization development Y1 - 2017 U6 - https://doi.org/10.1080/14697017.2017.1299372 SN - 1469-7017 SN - 1479-1811 VL - 17 IS - 2 SP - 101 EP - 120 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Colombo, Stefanie M. A1 - Wacker, Alexander A1 - Parrish, Christopher C. A1 - Kainz, Martin J. A1 - Arts, Michael T. T1 - A fundamental dichotomy in long-chain polyunsaturated fatty acid abundance between and within marine and terrestrial ecosystems JF - Environmental reviews = Dossiers environnement N2 - Polyunsaturated fatty acids (PUFA), especially long-chain (i.e., >= 20 carbons) polyunsaturated fatty acids (LC-PUFA), are fundamental to the health and survival of marine and terrestrial organisms. Therefore, it is imperative that we gain a better understanding of their origin, abundance, and transfer between and within these ecosystems. We evaluated the natural variation in PUFA distribution and abundance that exists between and within these ecosystems by amassing and analyzing, using multivariate and analysis of variance (ANOVA) methods, >3000 fatty acid (FA) profiles from marine and terrestrial organisms. There was a clear dichotomy in LC-PUFA abundance between organisms in marine and terrestrial ecosystems, mainly driven by the C-18 PUFA in terrestrial organisms and omega-3 (n-3) LC-PUFA in marine organisms. The PUFA content of an organism depended on both its biome (marine vs terrestrial) and taxonomic group. Within the marine biome, the PUFA content varied among taxonomic groups. PUFA content of marine organisms was dependent on both geographic zone (i.e., latitude, and thus broadly related to temperature) and trophic level (a function of diet). The contents of n-3 LC-PUFA were higher in polar and temperate marine organisms than those from the tropics. Therefore, we conclude that, on a per capita basis, high latitude marine organisms provide a disproportionately large global share of these essential nutrients to consumers, including terrestrial predators. Our analysis also hints at how climate change, and other anthropogenic stressors, might act to negatively impact the global distribution and abundance of n-3 LC-PUFA within marine ecosystems and on the terrestrial consumers that depend on these subsidies. KW - climate change KW - food webs KW - omega-3 KW - polyunsaturated fatty acids KW - trophic ecology Y1 - 2017 U6 - https://doi.org/10.1139/er-2016-0062 SN - 1208-6053 SN - 1181-8700 VL - 25 SP - 163 EP - 174 PB - NRC Research Press CY - Ottawa ER - TY - JOUR A1 - Lachmann, Sabrina C. A1 - Maberly, Stephen C. A1 - Spijkerman, Elly T1 - Species-specific influence of P-i-status on inorganic carbon acquisition in microalgae (Chlorophyceae) JF - Botany N2 - Inorganic phosphorus (P-i) is often the primary limiting nutrient in freshwater ecosystems. Since P(i-)limitation affects energy transduction, and inorganic carbon (C-i) acquisition can be energy demanding, C(i-)acquisition strategies were compared in four species of green algae grown under P-i-replete and P-i-limited conditions predominantly at low and partly at high CO2. Although P-i-limitation was evident by the 10-fold higher cellular C:P ratio and enhanced phosphatase activity, it only decreased C-i-acquisition to a small extent. Nonetheless, the effects of Pi-limitation on both CO2 and HCO3- acquisition were demonstrated. Decreased CO2 acquisition under conditions of Pi limitation was mainly visible in the maximum uptake rate (V-max) and, for the neutrophile Scenedesmus vacuolatus, in the affinity for CO2 acquisition. Discrimination against C-13 was higher under P-i-limited, high CO2 conditions, compared with P-i-replete, highCO(2) conditions, in Chlamydomonas acidophila and S. vacuolatus. In the pH-drift experiments, HCO3- acquisition was reduced in P-i-limited C. reinhardtii. In general, energy demanding bicarbonate uptake was indicated by the less strong discrimination against (13)Cunder lowCO(2) conditions in the neutrophiles (HCO3- users), separating them from the acidophilic or acidotolerant species (CO2 users). The high variability of the influence of Pi supply among different green algal species is linked to their species-specific C(i-)acquisition strategies. KW - CCM KW - Chlamydomonas KW - inorganic carbon uptake kinetics KW - inorganic phosphorus limitation KW - stable carbon isotope discrimination Y1 - 2017 U6 - https://doi.org/10.1139/cjb-2017-0082 SN - 1916-2790 SN - 1916-2804 VL - 95 SP - 943 EP - 952 PB - NRC Research Press CY - Ottawa ER - TY - CHAP A1 - Torpey, John C. A1 - Turner, Bryan S. T1 - Demography and social citizenship T2 - The Transformation of Citizenship : Political Economy Y1 - 2017 SN - 978-1-138-67290-1 (print) SN - 978-1-315-56228-5 (online) IS - 1 SP - 188 EP - 203 PB - Routledge Taylor CY - London ER - TY - JOUR A1 - Smaczniak, Cezary A1 - Muino, Jose M. A1 - Chen, Dijun A1 - Angenent, Gerco C. A1 - Kaufmann, Kerstin T1 - Differences in DNA Binding Specificity of Floral Homeotic Protein Complexes Predict Organ-Specific Target Genes JF - The plant cell N2 - Floral organ identities in plants are specified by the combinatorial action of homeotic master regulatory transcription factors. However, how these factors achieve their regulatory specificities is still largely unclear. Genome-wide in vivo DNA binding data show that homeotic MADS domain proteins recognize partly distinct genomic regions, suggesting that DNA binding specificity contributes to functional differences of homeotic protein complexes. We used in vitro systematic evolution of ligands by exponential enrichment followed by high-throughput DNA sequencing (SELEX-seq) on several floral MADS domain protein homo-and heterodimers to measure their DNA binding specificities. We show that specification of reproductive organs is associated with distinct binding preferences of a complex formed by SEPALLATA3 and AGAMOUS. Binding specificity is further modulated by different binding site spacing preferences. Combination of SELEX-seq and genome-wide DNA binding data allows differentiation between targets in specification of reproductive versus perianth organs in the flower. We validate the importance of DNA binding specificity for organ-specific gene regulation by modulating promoter activity through targeted mutagenesis. Our study shows that intrafamily protein interactions affect DNA binding specificity of floral MADS domain proteins. Differential DNA binding of MADS domain protein complexes plays a role in the specificity of target gene regulation. Y1 - 2017 U6 - https://doi.org/10.1105/tpc.17.00145 SN - 1040-4651 SN - 1532-298X VL - 29 SP - 1822 EP - 1835 PB - American Society of Plant Physiologists CY - Rockville ER - TY - JOUR A1 - Bubeck, Philip A1 - Kreibich, Heidi A1 - Penning-Rowsell, E. C. A1 - Botzen, W. J. Wouter A1 - de Moel, H. A1 - Klijn, F. T1 - Explaining differences in flood management approaches in Europe and in the USA - a comparative analysis JF - Journal of flood risk management N2 - Flood risk management in Europe and worldwide is not static but constantly in a state of flux. There has been a trend towards more integrated flood risk management in many countries. However, the initial situation and the pace and direction of change is very different in the various countries. In this paper, we will present a conceptual framework that seeks to explain why countries opt for different flood risk management portfolios. The developed framework utilises insights from a range of policy science concepts in an integrated way and considers, among others, factors such as geographical characteristics, the experience with flood disasters, as well as human behavioural aspects. KW - Flood risk management KW - impact KW - policy Y1 - 2017 U6 - https://doi.org/10.1111/jfr3.12151 SN - 1753-318X VL - 10 SP - 436 EP - 445 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Voigt, Christian C. A1 - Roeleke, Manuel A1 - Marggraf, Lara A1 - Petersons, Gunars A1 - Voigt-Heucke, Silke L. T1 - Migratory bats respond to artificial green light with positive phototaxis JF - PLoS one Y1 - 2017 U6 - https://doi.org/10.1371/journal.pone.0177748 SN - 1932-6203 VL - 12 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Bruno, Giovanni A1 - Vogel, Sven C. T1 - Simultaneous determination of high-temperature crystal structure and texture of synthetic porous cordierite JF - Journal of applied crystallography N2 - The evolution of the crystal structure and crystallographic texture of porous synthetic cordierite was studied by in situ high-temperature neutron diffraction up to 1373 K, providing the first in situ high-temperature texture measurement of this technologically important material. It was observed that the crystal texture slightly weakens with increasing temperature, concurrently with subtle changes in the crystal structure. These changes are in agreement with previous work, leading the authors to the conclusion that high-temperature neutron diffraction allows reliable crystallographic characterization of materials with moderate texture. It was also observed that structural changes occur at about the glass transition temperature of the cordierite glass (between 973 and 1073 K). Crystal structure refinements were conducted with and without quantitative texture analysis being part of the Rietveld refinement, and a critical comparison of the results is presented, contributing to the sparse body of literature on combined texture and crystal structure refinements. KW - synthetic extruded cordierite KW - crystal texture KW - high temperature KW - atomic distances KW - atomic displacement parameters KW - neutron diffraction Y1 - 2017 U6 - https://doi.org/10.1107/S160057671700406X SN - 1600-5767 VL - 50 SP - 749 EP - 762 PB - International Union of Crystallography CY - Chester ER - TY - JOUR A1 - Müller, B. R. A1 - Cooper, R. C. A1 - Lange, A. A1 - Kupsch, Andreas A1 - Wheeler, M. A1 - Hentschel, M. P. A1 - Staude, A. A1 - Pandey, A. A1 - Shyam, A. A1 - Bruno, Giovanni T1 - Stress-induced microcrack density evolution in beta-eucryptite ceramics BT - experimental observations and possible route to strain hardening JF - Acta materialia N2 - In order to investigate their microcracking behaviour, the microstructures of several beta-eucryptite ceramics, obtained from glass precursor and cerammed to yield different grain sizes and microcrack densities, were characterized by laboratory and synchrotron x-ray refraction and tomography. Results were compared with those obtained from scanning electron microscopy (SEM). In SEM images, the characterized materials appeared fully dense but computed tomography showed the presence of pore clusters. Uniaxial tensile testing was performed on specimens while strain maps were recorded and analyzed by Digital Image Correlation (DIC). X-ray refraction techniques were applied on specimens before and after tensile testing to measure the amount of the internal specific surface (i.e., area per unit volume). X-ray refraction revealed that (a) the small grain size (SGS) material contained a large specific surface, originating from the grain boundaries and the interfaces of TiO2 precipitates; (b) the medium (MGS) and large grain size (LGS) materials possessed higher amounts of specific surface compared to SGS material due to microcracks, which decreased after tensile loading; (c) the precursor glass had negligible internal surface. The unexpected decrease in the internal surface of MGS and LGS after tensile testing is explained by the presence of compressive regions in the DIC strain maps and further by theoretical arguments. It is suggested that while some microcracks merge via propagation, more close mechanically, thereby explaining the observed X-ray refraction results. The mechanisms proposed would allow the development of a strain hardening route in ceramics. KW - Beta-eucryptite KW - Microcracked ceramics KW - X-ray refraction KW - Tensile load KW - Strain hardening Y1 - 2017 U6 - https://doi.org/10.1016/j.actamat.2017.10.030 SN - 1359-6454 SN - 1873-2453 VL - 144 SP - 627 EP - 641 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Cooper, Ryan C. A1 - Bruno, Giovanni A1 - Wheeler, M. R. A1 - Pandey, A. A1 - Watkins, T. R. A1 - Shyarn, A. T1 - Effect of microcracking on the uniaxial tensile response of beta-eucryptite ceramics BT - Experiments and constitutive model JF - Acta Materialia N2 - A constitutive model for the nonlinear or "pseudoplastic" mechanical behavior in a linear-elastic solid with thermally induced microcracks is developed and applied to experimental results. The model is termed strain dependent microcrack density approximation (SDMDA) and is an extension of the modified differential scheme that describes the slope of the stress-strain curves of microcracked solids. SDMDA allows a continuous variation in the microcrack density with tensile loading. Experimental uniaxial tensile response of beta-eucryptite glass and ceramics with controlled levels of microcracking is reported. It is demonstrated that SDMDA can well describe the extent of non-linearity in the experimental uniaxial tensile response of beta-eucryptite with varying levels of microcracking. The advantages of the SDMDA are discussed in regard to tensile loading. KW - behavior Y1 - 2017 U6 - https://doi.org/10.1016/j.actamat.2017.06.033 SN - 1359-6454 SN - 1873-2453 VL - 135 SP - 361 EP - 371 PB - Elsevier CY - Oxford ER - TY - GEN A1 - Beaumont, Robin N. A1 - Warrington, Nicole M. A1 - Cavadino, Alana A1 - Tyrrell, Jessica A1 - Nodzenski, Michael A1 - Horikoshi, Momoko A1 - Geller, Frank A1 - Myhre, Ronny A1 - Richmond, Rebecca C. A1 - Paternoster, Lavinia A1 - Bradfield, Jonathan P. A1 - Kreiner-Møller, Eskil A1 - Huikari, Ville A1 - Metrustry, Sarah A1 - Lunetta, Kathryn L. A1 - Painter, Jodie N. A1 - Hottenga, Jouke-Jan A1 - Allard, Catherine A1 - Barton, Sheila J. A1 - Espinosa, Ana A1 - Marsh, Julie A. A1 - Potter, Catherine A1 - Zhang, Ge A1 - Ang, Wei A1 - Berry, Diane J. A1 - Bouchard, Luigi A1 - Das, Shikta A1 - Hakonarson, Hakon A1 - Heikkinen, Jani A1 - Helgeland, Øyvind A1 - Hocher, Berthold A1 - Hofman, Albert A1 - Inskip, Hazel M. A1 - Jones, Samuel E. A1 - Kogevinas, Manolis A1 - Lind, Penelope A. A1 - Marullo, Letizia A1 - Medland, Sarah E. A1 - Murray, Anna A1 - Murray, Jeffrey C. A1 - Njølstad, Pa ̊l R. A1 - Nohr, Ellen A. A1 - Reichetzeder, Christoph A1 - Ring, Susan M. A1 - Ruth, Katherine S. A1 - Santa-Marina, Loreto A1 - Scholtens, Denise M. A1 - Sebert, Sylvain A1 - Sengpiel, Verena A1 - Tuke, Marcus A. A1 - Vaudel, Marc A1 - Weedon, Michael N. A1 - Willemsen, Gonneke A1 - Wood, Andrew R. A1 - Yaghootkar, Hanieh A1 - Muglia, Louis J. A1 - Bartels, Meike A1 - Relton, Caroline L. A1 - Pennell, Craig E. A1 - Chatzi, Leda A1 - Estivill, Xavier A1 - Holloway, John W. A1 - Boomsma, Dorret I. A1 - Montgomery, Grant W. A1 - Murabito, Joanne M. A1 - Spector, Tim D. A1 - Power, Christine A1 - Ja ̈rvelin, Marjo-Ritta A1 - Bisgaard, Hans A1 - Grant, Struan F.A. A1 - Sørensen, Thorkild I.A. A1 - Jaddoe, Vincent W. A1 - Jacobsson, Bo A1 - Melbye, Mads A1 - McCarthy, Mark I. A1 - Hattersley, Andrew T. A1 - Hayes, M. Geoffrey A1 - Frayling, Timothy M. A1 - Hivert, Marie-France A1 - Felix, Janine F. A1 - Hyppo ̈nen, Elina A1 - Lowe, William L. , Jr A1 - Evans, David M. A1 - Lawlor, Debbie A. A1 - Feenstra, Bjarke A1 - Freathy, Rachel M. T1 - Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Genome-wide association studies of birth weight have focused on fetal genetics, whereas relatively little is known about the role of maternal genetic variation. We aimed to identify maternal genetic variants associated with birth weight that could highlight potentially relevant maternal determinants of fetal growth. We meta-analysed data on up to 8.7 million SNPs in up to 86 577 women of European descent from the Early Growth Genetics (EGG) Consortium and the UK Biobank. We used structural equation modelling (SEM) and analyses of mother–child pairs to quantify the separate maternal and fetal genetic effects. Maternal SNPs at 10 loci (MTNR1B, HMGA2, SH2B3, KCNAB1, L3MBTL3, GCK, EBF1, TCF7L2, ACTL9, CYP3A7) were associated with offspring birth weight at P < 5 Â 10 À8 . In SEM analyses, at least 7 of the 10 associations were consistent with effects of the maternal genotype acting via the intrauterine environment, rather than via effects of shared alleles with the fetus. Variants, or correlated proxies, at many of the loci had been previously associated with adult traits, including fasting glucose (MTNR1B, GCK and TCF7L2) and sex hormone levels (CYP3A7), and one (EBF1) with gestational duration. The identified associations indicate that genetic effects on maternal glucose, cytochrome P450 activity and gestational duration, and potentially on maternal blood pressure and immune function, are relevant for fetal growth. Further characterization of these associations in mechanistic and causal analyses will enhance understanding of the potentially modifiable maternal determinants of fetal growth, with the goal of reducing the morbidity and mortality associated with low and high birth weights. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 628 KW - alleles KW - birth weight KW - fetus KW - genotype KW - mothers KW - single nucleotide polymorphism KW - genetics KW - duration of gestation KW - genome-wide association study KW - offspring KW - biobanks Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-423100 SN - 1866-8372 IS - 628 ER - TY - GEN A1 - Gosling, William D. A1 - Julier, Adele C. M. A1 - Adu-Bredu, Stephen A1 - Djagbletey, Gloria D. A1 - Fraser, Wesley T. A1 - Jardine, Phillip E. A1 - Lomax, Barry H. A1 - Malhi, Yadvinder A1 - Manu, Emmanuel A. A1 - Mayle, Francis E. A1 - Moore, Sam T1 - Pollen-vegetation richness and diversity relationships in the tropics T2 - Postprints der Universität Potsdam Mathematisch-Naturwissenschaftliche Reihe N2 - Tracking changes in biodiversity through time requires an understanding of the relationship between modern diversity and how this diversity is preserved in the fossil record. Fossil pollen is one way in which past vegetation diversity can be reconstructed. However, there is limited understanding of modern pollen-vegetation diversity relationships from biodiverse tropical ecosystems. Here, pollen (palynological) richness and diversity (Hill N (1)) are compared with vegetation richness and diversity from forest and savannah ecosystems in the New World and Old World tropics (Neotropics and Palaeotropics). Modern pollen data were obtained from artificial pollen traps deployed in 1-ha vegetation study plots from which vegetation inventories had been completed in Bolivia and Ghana. Pollen counts were obtained from 15 to 22 traps per plot, and aggregated pollen sums for each plot were > 2,500. The palynological richness/diversity values from the Neotropics were moist evergreen forest = 86/6.8, semi-deciduous dry forest = 111/21.9, wooded savannah = 138/31.5, and from the Palaeotropics wet evergreen forest = 144/28.3, semi-deciduous moist forest = 104/4.4, forest-savannah transition = 121/14.1; the corresponding vegetation richness/diversity was 100/36.7, 80/38.7 and 71/39.4 (Neotropics), and 101/54.8, 87/45.5 and 71/34.5 (Palaeotropics). No consistent relationship was found between palynological richness/diversity, and plot vegetation richness/diversity, due to the differential influence of other factors such as landscape diversity, pollination strategy, and pollen source area. Palynological richness exceeded vegetation richness, while pollen diversity was lower than vegetation diversity. The relatively high global diversity of tropical vegetation was found to be reflected in the pollen rain. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 562 KW - Neotropics KW - Palaeotropics KW - Palynology KW - Pollen trap KW - Forest-savannah KW - Savanna Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-423081 SN - 1866-8372 IS - 562 ER - TY - JOUR A1 - De Becker, M. A1 - del Valle, Maria Victoria A1 - Romero, G. E. A1 - Peri, C. S. A1 - Benaglia, P. T1 - X- ray study of bow shocks in runaway stars JF - Monthly notices of the Royal Astronomical Society N2 - Massive runaway stars produce bow shocks through the interaction of their winds with the interstellar medium, with the prospect for particle acceleration by the shocks. These objects are consequently candidates for non-thermal emission. Our aim is to investigate the X-ray emission from these sources. We observed with XMM-Newton a sample of five bow shock runaways, which constitutes a significant improvement of the sample of bow shock runaways studied in X-rays so far. A careful analysis of the data did not reveal any X-ray emission related to the bow shocks. However, X-ray emission from the stars is detected, in agreement with the expected thermal emission from stellar winds. On the basis of background measurements we derive conservative upper limits between 0.3 and 10 keV on the bow shocks emission. Using a simple radiation model, these limits together with radio upper limits allow us to constrain some of the main physical quantities involved in the non-thermal emission processes, such as the magnetic field strength and the amount of incident infrared photons. The reasons likely responsible for the non-detection of non-thermal radiation are discussed. Finally, using energy budget arguments, we investigate the detectability of inverse Compton X-rays in a more extended sample of catalogued runaway star bow shocks. From our analysis we conclude that a clear identification of non-thermal X-rays from massive runaway bow shocks requires one order of magnitude (or higher) sensitivity improvement with respect to present observatories. KW - acceleration of particles KW - radiation mechanisms: non-thermal KW - stars: earlytype KW - X-rays: stars Y1 - 2017 U6 - https://doi.org/10.1093/mnras/stx1826 SN - 0035-8711 SN - 1365-2966 VL - 471 SP - 4452 EP - 4464 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Fromm, T. A1 - Jokat, W. A1 - Ryberg, T. A1 - Behrmann, Jan H. A1 - Haberland, C. A1 - Weber, Michael T1 - The onset of Walvis Ridge: Plume influence at the continental margin JF - Tectonophysics : international journal of geotectonics and the geology and physics of the interior of the earth N2 - The opening of the South Atlantic is a classical example for a plume related continental breakup. Flood basalts are present on both conjugate margins as well as aseismic ridges connecting them with the current plume location at Tristan da Cunha. To determine the effect of the proposed plume head on the continental crust, we acquired wide-angle seismic data at the junction of the Walvis Ridge with the African continent and modelled the P-wave velocity structure in a forward approach. The profile extends 430 km along the ridge and continues onshore to a length of 720 km. Crustal velocities beneath the Walvis Ridge vary between 5.5 km/s and 7.0 km/s, a typical range for oceanic crust. The crustal thickness of 22 km, however, is approximately three times larger than of normal oceanic crust. The continent-ocean transition is characterized by 30 km thick crust with strong lateral velocity variations in the upper crust and a high-velocity lower crust (HVLC), where velocities reach up to 7.5 km/s. The HVLC is 100 to 130 km wider at the Walvis Ridge than it is farther south, and impinges onto the continental crust of the Kaoko fold belt. Such high seismic velocities indicate Mg-rich igneous material intruded into the continental crust during the initial rifting stage. However, the remaining continental crust seems unaffected by intrusions and the root of the 40 km-thick crust of the Kaoko belt is not thermally abraded. We conclude that the plume head did not modify the continental crust on a large scale, but caused rather local effects. Thus, it seems unlikely that a plume drove or initiated the breakup process. We further propose that the plume already existed underneath the continent prior to the breakup, and ponded melt erupted at emerging rift structures providing the magma for continental flood basalts. (C) 2017 Elsevier B.V. All rights reserved. Y1 - 2017 U6 - https://doi.org/10.1016/j.tecto.2017.03.011 SN - 0040-1951 SN - 1879-3266 VL - 716 SP - 90 EP - 107 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - van der Lubbe, H. J. L. A1 - Krause-Nehring, J. A1 - Junginger, A. A1 - Garcin, Yannick A1 - Joordens, J. C. A. A1 - Davies, G. R. A1 - Beck, C. A1 - Feibel, C. S. A1 - Johnson, T. C. A1 - Vonhof, H. B. T1 - Gradual or abrupt? Changes in water source of Lake Turkana (Kenya) during the African Humid Period inferred from Sr isotope ratios JF - Quaternary science reviews : the international multidisciplinary research and review journal Y1 - 2017 U6 - https://doi.org/10.1016/j.quascirev.2017.08.010 SN - 0277-3791 VL - 174 SP - 1 EP - 12 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Renteria, Miguel E. A1 - Schmaal, L. A1 - Hibar, D. P. A1 - Couvy-Duchesne, B. A1 - Strike, L. T. A1 - Mills, N. T. A1 - de Zubicaray, Greig. I. A1 - McMahon, Katie. L. A1 - Medland, Sarah E. A1 - Gillespie, N. A. A1 - Hatton, S. N. A1 - Lagopoulos, J. A1 - Veltman, D. J. A1 - van der Wee, N. A1 - van Erp, T. G. M. A1 - Wittfeld, K. A1 - Grabe, H. J. A1 - Block, Andrea A1 - Hegenscheid, K. A1 - Voelzke, H. A1 - Veer, I. M. A1 - Walter, H. A1 - Schnell, K. A1 - Schramm, E. A1 - Normann, C. A1 - Schoepf, Dieter A1 - Konrad, C. A1 - Zurowski, B. A1 - Godlewska, B. R. A1 - Cowen, P. J. A1 - Penninx, B. W. J. H. A1 - Jahanshad, N. A1 - Thompson, Paul M. A1 - Wright, M. J. A1 - Martin, N. G. A1 - Christensen, H. A1 - Hickie, I. B. T1 - Subcortical brain structure and suicidal behaviour in major depressive disorder: a meta-analysis from the ENIGMA-MDD working group JF - Translational Psychiatry Y1 - 2017 U6 - https://doi.org/10.1038/tp.2017.84 SN - 2158-3188 VL - 7 SP - 2301 EP - 2320 PB - Nature Publ. Group CY - New York ER - TY - JOUR A1 - Pratt, Jane A1 - Busse, Angela A1 - Mueller, W-C A1 - Watkins, Nikolas W. A1 - Chapman, Sandra C. T1 - Extreme-value statistics from Lagrangian convex hull analysis for homogeneous turbulent Boussinesq convection and MHD convection JF - New journal of physics : the open-access journal for physics N2 - We investigate the utility of the convex hull of many Lagrangian tracers to analyze transport properties of turbulent flows with different anisotropy. In direct numerical simulations of statistically homogeneous and stationary Navier-Stokes turbulence, neutral fluid Boussinesq convection, and MHD Boussinesq convection a comparison with Lagrangian pair dispersion shows that convex hull statistics capture the asymptotic dispersive behavior of a large group of passive tracer particles. Moreover, convex hull analysis provides additional information on the sub-ensemble of tracers that on average disperse most efficiently in the form of extreme value statistics and flow anisotropy via the geometric properties of the convex hulls. We use the convex hull surface geometry to examine the anisotropy that occurs in turbulent convection. Applying extreme value theory, we show that the maximal square extensions of convex hull vertices are well described by a classic extreme value distribution, the Gumbel distribution. During turbulent convection, intermittent convective plumes grow and accelerate the dispersion of Lagrangian tracers. Convex hull analysis yields information that supplements standard Lagrangian analysis of coherent turbulent structures and their influence on the global statistics of the flow. KW - turbulence KW - magnetohydrodynamics KW - Lagrangian statistics KW - magnetoconvection KW - turbulent transport Y1 - 2017 U6 - https://doi.org/10.1088/1367-2630/aa6fe8 SN - 1367-2630 VL - 19 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Bemer, Marian A1 - van Mourik, Hilda A1 - Muino, Jose M. A1 - Ferrandiz, Cristina A1 - Kaufmann, Kerstin A1 - Angenent, Gerco C. T1 - FRUITFULL controls SAUR10 expression and regulates Arabidopsis growth and architecture JF - Journal of experimental botany N2 - MADS-domain transcription factors are well known for their roles in plant development and regulate sets of downstream genes that have been uncovered by high-throughput analyses. A considerable number of these targets are predicted to function in hormone responses or responses to environmental stimuli, suggesting that there is a close link between developmental and environmental regulators of plant growth and development. Here, we show that the Arabidopsis MADS-domain factor FRUITFULL (FUL) executes several functions in addition to its noted role in fruit development. Among the direct targets of FUL, we identified SMALL AUXIN UPREGULATED RNA 10 (SAUR10), a growth regulator that is highly induced by a combination of auxin and brassinosteroids and in response to reduced R:FR light. Interestingly, we discovered that SAUR10 is repressed by FUL in stems and inflorescence branches. SAUR10 is specifically expressed at the abaxial side of these branches and this localized activity is influenced by hormones, light conditions and by FUL, which has an effect on branch angle. Furthermore, we identified a number of other genes involved in hormone pathways and light signalling as direct targets of FUL in the stem, demonstrating a connection between developmentally and environmentally regulated growth programs. KW - Architecture KW - auxin KW - branching KW - FRUITFULL KW - growth KW - hormones KW - light response KW - MADS-box transcription factor KW - SAUR Y1 - 2017 U6 - https://doi.org/10.1093/jxb/erx184 SN - 0022-0957 SN - 1460-2431 VL - 68 SP - 3391 EP - 3403 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Huss, Matthias A1 - Bookhagen, Bodo A1 - Huggel, C. A1 - Jacobsen, Dean A1 - Bradley, Raymond S. A1 - Clague, J. J. A1 - Vuille, Mathias A1 - Buytaert, Wouter A1 - Cayan, D. R. A1 - Greenwood, G. A1 - Mark, B. G. A1 - Milner, A. M. A1 - Weingartner, Rolf A1 - Winder, M. T1 - Toward mountains without permanent snow and ice JF - Earths future N2 - The cryosphere in mountain regions is rapidly declining, a trend that is expected to accelerate over the next several decades due to anthropogenic climate change. A cascade of effects will result, extending from mountains to lowlands with associated impacts on human livelihood, economy, and ecosystems. With rising air temperatures and increased radiative forcing, glaciers will become smaller and, in some cases, disappear, the area of frozen ground will diminish, the ratio of snow to rainfall will decrease, and the timing and magnitude of both maximum and minimum streamflow will change. These changes will affect erosion rates, sediment, and nutrient flux, and the biogeochemistry of rivers and proglacial lakes, all of which influence water quality, aquatic habitat, and biotic communities. Changes in the length of the growing season will allow low-elevation plants and animals to expand their ranges upward. Slope failures due to thawing alpine permafrost, and outburst floods from glacier-and moraine-dammed lakes will threaten downstream populations.Societies even well beyond the mountains depend on meltwater from glaciers and snow for drinking water supplies, irrigation, mining, hydropower, agriculture, and recreation. Here, we review and, where possible, quantify the impacts of anticipated climate change on the alpine cryosphere, hydrosphere, and biosphere, and consider the implications for adaptation to a future of mountains without permanent snow and ice. Y1 - 2017 U6 - https://doi.org/10.1002/2016EF000514 SN - 2328-4277 VL - 5 SP - 418 EP - 435 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Reinicke, Stefan A1 - Rees, Huw C. A1 - Espeel, Pieter A1 - Vanparijs, Nane A1 - Bisterfeld, Carolin A1 - Dick, Markus A1 - Rosencrantz, Ruben R. A1 - Brezesinski, Gerald A1 - de Geest, Bruno G. A1 - Du Prez, Filip E. A1 - Pietruszka, Jörg A1 - Böker, Alexander T1 - Immobilization of 2-Deoxy-D-ribose-5-phosphate Aldolase in Polymeric Thin Films via the Langmuir-Schaefer Technique JF - ACS applied materials & interfaces N2 - A synthetic protocol for the fabrication of ultrathin polymeric films containing the enzyme 2-deoxy-D-ribose-5-phosphate aldolase from Escherichia coli (DERA(EC)) is presented. Ultrathin enzymatically active films are useful for applications in which only small quantities of active material are needed and at the same time quick response and contact times without diffusion limitation are wanted. We show how DERA as an exemplary enzyme can be immobilized in a thin polymer layer at the air-water interface and transferred to a suitable support by the Langmuir-Schaefer technique under full conservation of enzymatic activity. The polymer in use is a poly(N-isopropylacrylamide-co-N-2-thiolactone acrylamide) (P(NIPAAm-co-TlaAm)) statistical copolymer in which the thiolactone units serve a multitude of purposes including hydrophobization of the polymer, covalent binding of the enzyme and the support and finally cross-linking of the polymer matrix. The application of this type of polymer keeps the whole approach simple as additional cocomponents such as cross-linkers are avoided. KW - Langmuir-Schaefer KW - enzyme immobilization KW - 2-deoxy-D-ribose-5-phosphate aldolase KW - polymeric thin film KW - poly(N-isopropylacrylamide) KW - thiolactone Y1 - 2017 U6 - https://doi.org/10.1021/acsami.6b13632 SN - 1944-8244 VL - 9 SP - 8317 EP - 8326 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Toy, Virginia Gail A1 - Sutherland, Rupert A1 - Townend, John A1 - Allen, Michael J. A1 - Becroft, Leeza A1 - Boles, Austin A1 - Boulton, Carolyn A1 - Carpenter, Brett A1 - Cooper, Alan A1 - Cox, Simon C. A1 - Daube, Christopher A1 - Faulkner, D. R. A1 - Halfpenny, Angela A1 - Kato, Naoki A1 - Keys, Stephen A1 - Kirilova, Martina A1 - Kometani, Yusuke A1 - Little, Timothy A1 - Mariani, Elisabetta A1 - Melosh, Benjamin A1 - Menzies, Catriona D. A1 - Morales, Luiz A1 - Morgan, Chance A1 - Mori, Hiroshi A1 - Niemeijer, Andre A1 - Norris, Richard A1 - Prior, David A1 - Sauer, Katrina A1 - Schleicher, Anja Maria A1 - Shigematsu, Norio A1 - Teagle, Damon A. H. A1 - Tobin, Harold A1 - Valdez, Robert A1 - Williams, Jack A1 - Yeo, Samantha A1 - Baratin, Laura-May A1 - Barth, Nicolas A1 - Benson, Adrian A1 - Boese, Carolin A1 - Célérier, Bernard A1 - Chamberlain, Calum J. A1 - Conze, Ronald A1 - Coussens, Jamie A1 - Craw, Lisa A1 - Doan, Mai-Linh A1 - Eccles, Jennifer A1 - Grieve, Jason A1 - Grochowski, Julia A1 - Gulley, Anton A1 - Howarth, Jamie A1 - Jacobs, Katrina A1 - Janku-Capova, Lucie A1 - Jeppson, Tamara A1 - Langridge, Robert A1 - Mallyon, Deirdre A1 - Marx, Ray A1 - Massiot, Cécile A1 - Mathewson, Loren A1 - Moore, Josephine A1 - Nishikawa, Osamu A1 - Pooley, Brent A1 - Pyne, Alex A1 - Savage, Martha K. A1 - Schmitt, Doug A1 - Taylor-Offord, Sam A1 - Upton, Phaedra A1 - Weaver, Konrad C. A1 - Wiersberg, Thomas A1 - Zimmer, Martin T1 - Bedrock geology of DFDP-2B, central Alpine Fault, New Zealand JF - New Zealand journal of geology and geophysics : an international journal of the geoscience of New Zealand, the Pacific Rim, and Antarctica ; NZJG N2 - During the second phase of the Alpine Fault, Deep Fault Drilling Project (DFDP) in the Whataroa River, South Westland, New Zealand, bedrock was encountered in the DFDP-2B borehole from 238.5–893.2 m Measured Depth (MD). Continuous sampling and meso- to microscale characterisation of whole rock cuttings established that, in sequence, the borehole sampled amphibolite facies, Torlesse Composite Terrane-derived schists, protomylonites and mylonites, terminating 200–400 m above an Alpine Fault Principal Slip Zone (PSZ) with a maximum dip of 62°. The most diagnostic structural features of increasing PSZ proximity were the occurrence of shear bands and reduction in mean quartz grain sizes. A change in composition to greater mica:quartz + feldspar, most markedly below c. 700 m MD, is inferred to result from either heterogeneous sampling or a change in lithology related to alteration. Major oxide variations suggest the fault-proximal Alpine Fault alteration zone, as previously defined in DFDP-1 core, was not sampled. KW - Alpine Fault KW - New Zealand KW - scientific drilling KW - mylonite KW - cataclasite Y1 - 2017 U6 - https://doi.org/10.1080/00288306.2017.1375533 SN - 0028-8306 SN - 1175-8791 VL - 60 IS - 4 SP - 497 EP - 518 PB - Taylor & Francis CY - Abingdon ER - TY - JOUR A1 - Maass, Stefanie A1 - Daphi, Daniel A1 - Lehmann, Anika A1 - Rillig, Matthias C. T1 - Transport of microplastics by two collembolan species JF - Environmental pollution N2 - Plastics, despite their great benefits, have become a ubiquitous environmental pollutant, with micro-plastic particles having come into focus most recently. Microplastic effects have been intensely studied in aquatic, especially marine systems; however, there is lack of studies focusing on effects on soil and its biota. A basic question is if and how surface-deposited microplastic particles are transported into the soil. We here wished to test if soil microarthropods, using Collembola, can transport these particles over distances of centimeters within days in a highly controlled experimental set-up. We conducted a fully factorial experiment with two collembolan species of differing body size, Folsomia candida and Proisotoma minuta, in combination with urea-formaldehyde particles of two different particle sizes. We observed significant differences between the species concerning the distance the particles were transported. F. candida was able to transport larger particles further and faster than P. minuta. Using video, we observed F candida interacting with urea-formaldehyde particles and polyethylene terephthalate fibers, showing translocation of both material types. Our data clearly show that microplastic particles can be moved and distributed by soil microarthropods. Although we did not observe feeding, it is possible that microarthropods contribute to the accumulation of microplastics in the soil food web. (C) 2017 Elsevier Ltd. All rights reserved. KW - Microplastics KW - Soil KW - Collembolans KW - Transport KW - Pollution Y1 - 2017 U6 - https://doi.org/10.1016/j.envpol.2017.03.009 SN - 0269-7491 SN - 1873-6424 VL - 225 SP - 456 EP - 459 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Gerecke, Christian A1 - Edlich, Alexander A1 - Giulbudagian, Michael A1 - Schumacher, Fabian A1 - Zhang, Nan A1 - Said, Andre A1 - Yealland, Guy A1 - Lohan, Silke B. A1 - Neumann, Falko A1 - Meinke, Martina C. A1 - Ma, Nan A1 - Calderon, Marcelo A1 - Hedtrich, Sarah A1 - Schaefer-Korting, Monika A1 - Kleuser, Burkhard T1 - Biocompatibility and characterization of polyglycerol-based thermoresponsive nanogels designed as novel drug-delivery systems and their intracellular localization in keratinocytes JF - Nanotoxicology N2 - Novel nanogels that possess the capacity to change their physico-chemical properties in response to external stimuli are promising drug-delivery candidates for the treatment of severe skin diseases. As thermoresponsive nanogels (tNGs) are capable of enhancing penetration through biological barriers such as the stratum corneum and are taken up by keratinocytes of human skin, potential adverse consequences of their exposure must be elucidated. In this study, tNGs were synthesized from dendritic polyglycerol (dPG) and two thermoresponsive polymers. tNG_dPG_tPG are the combination of dPG with poly(glycidyl methyl ether-co-ethyl glycidyl ether) (p(GME-co-EGE)) and tNG_dPG_pNIPAM the one with poly(N-isopropylacrylamide) (pNIPAM). Both thermoresponsive nanogels are able to incorporate high amounts of dexamethasone and tacrolimus, drugs used in the treatment of severe skin diseases. Cellular uptake, intracellular localization and the toxicological properties of the tNGs were comprehensively characterized in primary normal human keratinocytes (NHK) and in spontaneously transformed aneuploid immortal keratinocyte cell line from adult human skin (HaCaT). Laser scanning confocal microscopy revealed fluorescently labeled tNGs entered into the cells and localized predominantly within lysosomal compartments. MTT assay, comet assay and carboxy-H2DCFDA assay, demonstrated neither cytotoxic or genotoxic effects, nor any induction of reactive oxygen species of the tNGs in keratinocytes. In addition, both tNGs were devoid of eye irritation potential as shown by bovine corneal opacity and permeability (BCOP) test and red blood cell (RBC) hemolysis assay. Therefore, our study provides evidence that tNGs are locally well tolerated and underlines their potential for cutaneous drug delivery. KW - Drug delivery KW - nanoparticles KW - particle characterization KW - keratinocytes KW - nanotoxicology Y1 - 2017 U6 - https://doi.org/10.1080/17435390.2017.1292371 SN - 1743-5390 SN - 1743-5404 VL - 11 SP - 267 EP - 277 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Leto, Paolo A1 - Trigilio, C. A1 - Oskinova, Lida A1 - Ignace, R. A1 - Buemi, C. S. A1 - Umana, G. A1 - Ingallinera, A. A1 - Todt, Helge Tobias A1 - Leone, F. T1 - The detection of variable radio emission from the fast rotating magnetic hot B-star HR 7355 and evidence for its X-ray aurorae JF - Monthly notices of the Royal Astronomical Society N2 - In this paper, we investigate the multiwavelength properties of the magnetic early B-type star HR 7355. We present its radio light curves at several frequencies, taken with the Jansky Very Large Array, and X-ray spectra, taken with the XMM-Newton X-ray telescope. Modelling of the radio light curves for the Stokes I and V provides a quantitative analysis of the HR 7355 magnetosphere. A comparison between HR 7355 and a similar analysis for the Ap star CU Vir allows us to study how the different physical parameters of the two stars affect the structure of the respective magnetospheres where the non-thermal electrons originate. Our model includes a cold thermal plasma component that accumulates at high magnetic latitudes that influences the radio regime, but does not give rise to X-ray emission. Instead, the thermal X-ray emission arises from shocks generated by wind stream collisions close to the magnetic equatorial plane. The analysis of the X-ray spectrum of HR 7355 also suggests the presence of a non-thermal radiation. Comparison between the spectral index of the power-law X-ray energy distribution with the non-thermal electron energy distribution indicates that the non-thermal X-ray component could be the auroral signature of the non-thermal electrons that impact the stellar surface, the same non-thermal electrons that are responsible for the observed radio emission. On the basis of our analysis, we suggest a novel model that simultaneously explains the X-ray and the radio features of HR 7355 and is likely relevant for magnetospheres of other magnetic early-type stars. KW - stars: chemically peculiar KW - stars: early-type KW - stars: individual: HR 7355 KW - stars: magnetic field KW - radio continuum: stars KW - X-rays: stars Y1 - 2017 U6 - https://doi.org/10.1093/mnras/stx267 SN - 0035-8711 SN - 1365-2966 VL - 467 SP - 2820 EP - 2833 PB - Oxford Univ. Press CY - Oxford ER - TY - GEN A1 - Heim, Olga A1 - Lorenz, Lukas A1 - Kramer-Schadt, Stephanie A1 - Jung, Kirsten A1 - Voigt, Christian C. A1 - Eccard, Jana T1 - Landscape and scale-dependent spatial niches of bats foraging above intensively used arable fields T2 - Postprints der Universität Potsdam : Mathematisch Naturwissenschaftliche Reihe N2 - Introduction Bats are threatened by agricultural intensification, and although bat ecology in agricultural landscapes is in the focus of current research, the effects of interacting spatiotemporal factors on species-specific bat activity above farmland remain understudied. Our aim was to identify spatiotemporal factors and their interactions relevant for the activity of bat species above conventionally managed arable fields. Methods We repeatedly monitored relative bat activity above open arable fields in Germany using acoustic monitoring. We used site-related biotic and abiotic factors and landscape characteristics across five spatial scales, their combinations, and interactions to identify those factors which best explain variation in bat activity. Results Numerous interactions between landscape characteristics and the insect abundance affected bat activity above fields. For instance, Pipistrellus pipistrellus became more active with increasing insect abundance, but only above fields with a low proportion of woody vegetation cover in the surroundings. Additionally, the level of bat activity in summer depended on landscape characteristics. For example, the activity of Pipistrellus nathusii was relatively low in summer above fields that were surrounded by vegetation patches with a high degree of edge complexity (e.g., hedgerow). However, the activity remained at a relatively high level and did not differ between seasons above fields that were surrounded by vegetation patches with a low degree of edge complexity (e.g., roundly shaped forest patch). Conclusions Our results revealed that landscape characteristics and their interactions with insect abundance affected bat activity above conventionally managed fields and highlighted the opportunistic foraging behavior of bats. To improve the conditions for bats in agricultural landscapes, we recommend re-establishing landscape heterogeneity to protect aquatic habitats and to increase arthropod availability. KW - AgroScapeLabs KW - european bat species KW - agriculture KW - landscape KW - multi-scale habitat modeling KW - ecosystem service KW - conservation Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-428166 IS - 826 ER - TY - JOUR A1 - Heim, Olga A1 - Lenski, Johannes A1 - Schulze, Jelena A1 - Jung, Kirsten A1 - Kramer-Schadt, Stephanie A1 - Eccard, Jana A1 - Voigt, Christian C. T1 - The relevance of vegetation structures and small water bodies for bats foraging above farmland JF - Basic and applied ecology : Journal of the Gesellschaft für Ökologie N2 - Bats are known to forage and commute close to vegetation structures when moving across the agricultural matrix, but the role of isolated landscape elements in arable fields for bat activity is unknown. Therefore, we investigated the influence of small isolated ponds which lie within arable fields close to vegetation structures on the flight and foraging activity of bats. Additionally, we compared species-specific activity measures between forest edges and linear structures such as hedgerows. We repeatedly recorded bat activity using passive acoustic monitoring along 20 transects extending from the vegetation edge up to 200 m into the arable field (hereafter: edge-field interface) with a small pond present at five transects per edge type (linear vs. forest). Using generalized linear mixed effect models, we analyzed the effects of edge type, pond presence and the season on species-specific flight and foraging activity within the edge-field interface. We found a higher flight activity of Nyctalus noctula and Pipistrellus pygmaeus above the arable field when a pond was present. Furthermore, Pipistrellus nathusii and Pipistrellus pipistrellus foraged more frequently at forest edges than at linear structures (e.g. hedgerows). Additionally, we found three major patterns of seasonal variation in the activity of bats along the edge-field interface. This study highlights the species-specific and dynamic use of forest and hedgerow or tree line edges by bats and their importance for different bat species in the agricultural landscape. Further, additional landscape elements such as small isolated ponds within arable fields might support the activity of bats above the open agricultural landscape, thereby facilitating agroecosystem functioning. Therefore, additional landscape elements within managed areas should be restored and protected against the conversion into arable land and better linked to surrounding landscape elements in order to efficiently support bats within the agroecosystem. KW - Hedgerow KW - Forest edge KW - Pond KW - European bats KW - Agricultural landscape KW - Wind turbines Y1 - 2017 U6 - https://doi.org/10.1016/j.baae.2017.12.001 SN - 1439-1791 SN - 1618-0089 VL - 27 SP - 9 EP - 19 PB - Elsevier GMBH CY - München ER - TY - GEN A1 - Stanke, S. A1 - Wenger, C. A1 - Bier, Frank Fabian A1 - Hölzel, Ralph T1 - Dielectrophoretic functionalization of nanoelectrode arrays for the detection of influenza viruses T2 - European biophysics journal : with biophysics letters ; an international journal of biophysics Y1 - 2017 SN - 0175-7571 SN - 1432-1017 VL - 46 SP - S337 EP - S337 PB - Springer CY - New York ER - TY - GEN A1 - Knigge, Xenia A1 - Wenger, C. A1 - Bier, Frank Fabian A1 - Hölzel, Ralph T1 - AC electrokinetic immobilisation of nanoobjects as individual singles in regular arrays T2 - European biophysics journal : with biophysics letters ; an international journal of biophysics Y1 - 2017 SN - 0175-7571 SN - 1432-1017 VL - 46 SP - S187 EP - S187 PB - Springer CY - New York ER - TY - GEN A1 - Laux, Eva-Maria A1 - Knigge, Xenia A1 - Wenger, C. A1 - Bier, Frank Fabian A1 - Hölzel, Ralph T1 - AC electrokinetic manipulation of nanoparticles and molecules T2 - European biophysics journal : with biophysics letters ; an international journal of biophysics Y1 - 2017 SN - 0175-7571 SN - 1432-1017 VL - 46 SP - S189 EP - S189 PB - Springer CY - New York ER - TY - GEN A1 - Laux, Eva-Maria A1 - Docoslis, A. A1 - Wenger, C. A1 - Bier, Frank Fabian A1 - Hölzel, Ralph T1 - Combination of dielectrophoresis and SERS for bacteria detection and characterization T2 - European biophysics journal : with biophysics letters ; an international journal of biophysics Y1 - 2017 SN - 0175-7571 SN - 1432-1017 VL - 46 SP - S331 EP - S331 PB - Springer CY - New York ER - TY - GEN A1 - Gerecke, Christian A1 - Edlich, Alexander A1 - Giulbudagian, Michael A1 - Schumacher, Fabian A1 - Zhang, Nan A1 - Said, Andre A1 - Yealland, Guy A1 - Lohan, Silke B. A1 - Neumann, Falko A1 - Meinke, Martina C. A1 - Ma, Nan A1 - Calderón, Marcelo A1 - Hedtrich, Sarah A1 - Schäfer-Korting, Monika A1 - Kleuser, Burkhard T1 - Biocompatibility and characterization of polyglycerol-based thermoresponsive nanogels designed as novel drug-delivery systems and their intracellular localization in keratinocytes N2 - Novel nanogels that possess the capacity to change their physico-chemical properties in response to external stimuli are promising drug-delivery candidates for the treatment of severe skin diseases. As thermoresponsive nanogels (tNGs) are capable of enhancing penetration through biological barriers such as the stratum corneum and are taken up by keratinocytes of human skin, potential adverse consequences of their exposure must be elucidated. In this study, tNGs were synthesized from dendritic polyglycerol (dPG) and two thermoresponsive polymers. tNG_dPG_tPG are the combination of dPG with poly(glycidyl methyl ether-co-ethyl glycidyl ether) (p(GME-co-EGE)) and tNG_dPG_pNIPAM the one with poly(N-isopropylacrylamide) (pNIPAM). Both thermoresponsive nanogels are able to incorporate high amounts of dexamethasone and tacrolimus, drugs used in the treatment of severe skin diseases. Cellular uptake, intracellular localization and the toxicological properties of the tNGs were comprehensively characterized in primary normal human keratinocytes (NHK) and in spontaneously transformed aneuploid immortal keratinocyte cell line from adult human skin (HaCaT). Laser scanning confocal microscopy revealed fluorescently labeled tNGs entered into the cells and localized predominantly within lysosomal compartments. MTT assay, comet assay and carboxy-H2DCFDA assay, demonstrated neither cytotoxic or genotoxic effects, nor any induction of reactive oxygen species of the tNGs in keratinocytes. In addition, both tNGs were devoid of eye irritation potential as shown by bovine corneal opacity and permeability (BCOP) test and red blood cell (RBC) hemolysis assay. Therefore, our study provides evidence that tNGs are locally well tolerated and underlines their potential for cutaneous drug delivery. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 335 KW - Drug delivery KW - nanoparticles KW - particle characterization KW - keratinocytes KW - nanotoxicology Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-395325 ER - TY - JOUR A1 - Vaz da Cruz, Vinicius A1 - Ertan, Emelie A1 - Couto, Rafael C. A1 - Eckert, Sebastian A1 - Fondell, Mattis A1 - Dantz, Marcus A1 - Kennedy, Brian A1 - Schmitt, Thorsten A1 - Pietzsch, Annette A1 - Guimaraes, Freddy F. A1 - Ågren, Hans A1 - Odelius, Michael A1 - Föhlisch, Alexander A1 - Kimberg, Victor T1 - A study of the water molecule using frequency control over nuclear dynamics in resonant X-ray scattering JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - In this combined theoretical and experimental study we report a full analysis of the resonant inelastic X-ray scattering (RIXS) spectra of H2O, D2O and HDO. We demonstrate that electronically-elastic RIXS has an inherent capability to map the potential energy surface and to perform vibrational analysis of the electronic ground state in multimode systems. We show that the control and selection of vibrational excitation can be performed by tuning the X-ray frequency across core-excited molecular bands and that this is clearly reflected in the RIXS spectra. Using high level ab initio electronic structure and quantum nuclear wave packet calculations together with high resolution RIXS measurements, we discuss in detail the mode coupling, mode localization and anharmonicity in the studied systems. Y1 - 2017 U6 - https://doi.org/10.1039/c7cp01215b SN - 1463-9076 SN - 1463-9084 VL - 19 SP - 19573 EP - 19589 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Couto, Rafael C. A1 - Cruz, Vinicius V. A1 - Ertan, Emelie A1 - Eckert, Sebastian A1 - Fondell, Mattis A1 - Dantz, Marcus A1 - Kennedy, Brian A1 - Schmitt, Thorsten A1 - Pietzsch, Annette A1 - Guimaraes, Freddy F. A1 - Agren, Hans A1 - Odelius, Michael A1 - Kimberg, Victor A1 - Föhlisch, Alexander T1 - Selective gating to vibrational modes through resonant X-ray scattering JF - Nature Communications N2 - The dynamics of fragmentation and vibration of molecular systems with a large number of coupled degrees of freedom are key aspects for understanding chemical reactivity and properties. Here we present a resonant inelastic X-ray scattering (RIXS) study to show how it is possible to break down such a complex multidimensional problem into elementary components. Local multimode nuclear wave packets created by X-ray excitation to different core-excited potential energy surfaces (PESs) will act as spatial gates to selectively probe the particular ground-state vibrational modes and, hence, the PES along these modes. We demonstrate this principle by combining ultra-high resolution RIXS measurements for gas-phase water with state-of-the-art simulations. Y1 - 2017 U6 - https://doi.org/10.1038/ncomms14165 SN - 2041-1723 VL - 8 PB - Nature Publ. Group CY - London ER - TY - GEN A1 - Couto, Rafael C. A1 - Cruz, Vinicius V. A1 - Ertan, Emelie A1 - Eckert, Sebastian A1 - Fondell, Mattis A1 - Dantz, Marcus A1 - Kennedy, Brian A1 - Schmitt, Thorsten A1 - Pietzsch, Annette A1 - Guimarães, Freddy F. A1 - Ågren, Hans A1 - Gel’mukhanov, Faris A1 - Odelius, Michael A1 - Kimberg, Victor A1 - Föhlisch, Alexander T1 - Selective gating to vibrational modes through resonant X-ray scattering T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - The dynamics of fragmentation and vibration of molecular systems with a large number of coupled degrees of freedom are key aspects for understanding chemical reactivity and properties. Here we present a resonant inelastic X-ray scattering (RIXS) study to show how it is possible to break down such a complex multidimensional problem into elementary components. Local multimode nuclear wave packets created by X-ray excitation to different core-excited potential energy surfaces (PESs) will act as spatial gates to selectively probe the particular ground-state vibrational modes and, hence, the PES along these modes. We demonstrate this principle by combining ultra-high resolution RIXS measurements for gas-phase water with state-of-the-art simulations. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1124 KW - potential-energy surface KW - raman-scattering KW - water-vapor KW - spectroscopy KW - chemistry KW - molecule KW - spectrum KW - CM(-1) KW - states KW - NM Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-436926 SN - 1866-8372 IS - 1124 ER - TY - GEN A1 - Vaz da Cruz, Vinicius A1 - Ertan, Emelie A1 - Couto, Rafael C. A1 - Eckert, Sebastian A1 - Fondell, Mattis A1 - Dantz, Marcus A1 - Kennedy, Brian A1 - Schmitt, Thorsten A1 - Pietzsch, Annette A1 - Guimarães, Freddy F. A1 - Ågren, Hans A1 - Gel'mukhanov, Faris A1 - Odelius, Michael A1 - Föhlisch, Alexander A1 - Kimberg, Victor T1 - A study of the water molecule using frequency control over nuclear dynamics in resonant X-ray scattering T2 - Postprints der Universität Potsdam Mathematisch-Naturwissenschaftliche Reihe N2 - In this combined theoretical and experimental study we report a full analysis of the resonant inelastic X-ray scattering (RIXS) spectra of H2O, D2O and HDO. We demonstrate that electronically-elastic RIXS has an inherent capability to map the potential energy surface and to perform vibrational analysis of the electronic ground state in multimode systems. We show that the control and selection of vibrational excitation can be performed by tuning the X-ray frequency across core-excited molecular bands and that this is clearly reflected in the RIXS spectra. Using high level ab initio electronic structure and quantum nuclear wave packet calculations together with high resolution RIXS measurements, we discuss in detail the mode coupling, mode localization and anharmonicity in the studied systems. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 781 KW - raman-scattering KW - vibrational structure KW - fast dissociation KW - auger spectrum KW - liquid water KW - spectroscopy KW - emission KW - collapse KW - states KW - vapor Y1 - 2019 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-436901 SN - 1866-8372 IS - 781 SP - 19573 EP - 19589 ER - TY - JOUR A1 - Hoehn, Richard S. A1 - Jernigan, Peter L. A1 - Japtok, Lukasz A1 - Chang, Alex L. A1 - Midura, Emily F. A1 - Caldwell, Charles C. A1 - Kleuser, Burkhard A1 - Lentsch, Alex B. A1 - Edwards, Michael J. A1 - Gulbins, Erich A1 - Pritts, Timothy A. T1 - Acid sphingomyelinase inhibition in stored erythrocytes reduces transfusion-associated lung inflammation JF - Annals of surgery : a monthly review of surgical science and practice N2 - Objective: We aimed to identify the role of the enzyme acid sphingomyelinase in the aging of stored units of packed red blood cells (pRBCs) and subsequent lung inflammation after transfusion. Summary Background Data: Large volume pRBC transfusions are associated with multiple adverse clinical sequelae, including lung inflammation. Microparticles are formed in stored pRBCs over time and have been shown to contribute to lung inflammation after transfusion. Methods: Human and murine pRBCs were stored with or without amitriptyline, a functional inhibitor of acid sphingomyelinase, or obtained from acid sphingomyelinase-deficient mice, and lung inflammation was studied in mice receiving transfusions of pRBCs and microparticles isolated from these units. Results: Acid sphingomyelinase activity in pRBCs was associated with the formation of ceramide and the release of microparticles. Treatment of pRBCs with amitriptyline inhibited acid sphingomyelinase activity, ceramide accumulation, and microparticle production during pRBC storage. Transfusion of aged pRBCs or microparticles isolated from aged blood into mice caused lung inflammation. This was attenuated after transfusion of pRBCs treated with amitriptyline or from acid sphingomyelinase-deficient mice. Conclusions: Acid sphingomyelinase inhibition in stored pRBCs offers a novel mechanism for improving the quality of stored blood. KW - acid sphingomyelinase KW - blood banking KW - ceramide KW - lung inflammation KW - microparticle Y1 - 2017 U6 - https://doi.org/10.1097/SLA.0000000000001648 SN - 0003-4932 SN - 1528-1140 VL - 265 IS - 1 SP - 218 EP - 226 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Halibasic, Emina A1 - Fuerst, Elisabeth A1 - Heiden, Denis A1 - Japtok, Lukasz A1 - Diesner, Susanne C. A1 - Hillebrand, P. A1 - Trauner, Michael A1 - Kleuser, Burkhard A1 - Kazemi-Shirazi, Lili A1 - Untersmayr, Eva T1 - Significantly reduced plasma levels of the bioactive sphingolipid S1P in lung transplanted cystic fibrosis patients are associated with gastrointestinal symptoms T2 - Allergy Y1 - 2017 SN - 0105-4538 SN - 1398-9995 VL - 72 IS - S103 SP - 195 EP - 195 PB - Wiley CY - Hoboken ER - TY - GEN A1 - Morf, Carolyn C. A1 - Schürch, Eva A1 - Küfner, Albrecht A1 - Siegrist, Philip A1 - Vater, Aline A1 - Back, Mitja A1 - Mestel, Robert A1 - Schröder-Abé, Michela T1 - Expanding the nomological net of the pathological narcissism inventory BT - German validation and extension in a clinical inpatient sample T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - The Pathological Narcissism Inventory (PNI) is a multidimensional measure for assessing grandiose and vulnerable features in narcissistic pathology. The aim of the present research was to construct and validate a German translation of the PNI and to provide further information on the PNI's nomological net. Findings from a first study confirm the psychometric soundness of the PNI and replicate its seven-factor first-order structure. A second-order structure was also supported but with several equivalent models. A second study investigating associations with a broad range of measures (DSM Axis I and II constructs, emotions, personality traits, interpersonal and dysfunctional behaviors, and well-being) supported the concurrent validity of the PNI. Discriminant validity with the Narcissistic Personality Inventory was also shown. Finally, in a third study an extension in a clinical inpatient sample provided further evidence that the PNI is a useful tool to assess the more pathological end of narcissism. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 410 KW - narcissism KW - assessment KW - Pathological Narcissism Inventory KW - construct validity KW - nomological network Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-405182 IS - 410 ER - TY - JOUR A1 - Sommer, C. A1 - Garbusow, Maria A1 - Juenger, E. A1 - Pooseh, S. A1 - Bernhardt, Nadine A1 - Birkenstock, J. A1 - Schad, Daniel A1 - Jabs, B. A1 - Gloeckler, T. A1 - Huys, Quentin J. M. A1 - Heinz, A. A1 - Smolka, Michael N. A1 - Zimmermann, Ulrich S. T1 - Strong seduction: impulsivity and the impact of contextual cues on instrumental behavior in alcohol dependence JF - Translational Psychiatry N2 - Alcohol-related cues acquire incentive salience through Pavlovian conditioning and then can markedly affect instrumental behavior of alcohol-dependent patients to promote relapse. However, it is unclear whether similar effects occur with alcohol-unrelated cues. We tested 116 early-abstinent alcohol-dependent patients and 91 healthy controls who completed a delay discounting task to assess choice impulsivity, and a Pavlovian-to-instrumental transfer (PIT) paradigm employing both alcohol-unrelated and alcohol-related stimuli. To modify instrumental choice behavior, we tiled the background of the computer screen either with conditioned stimuli (CS) previously generated by pairing abstract pictures with pictures indicating monetary gains or losses, or with pictures displaying alcohol or water beverages. CS paired to money gains and losses affected instrumental choices differently. This PIT effect was significantly more pronounced in patients compared to controls, and the group difference was mainly driven by highly impulsive patients. The PIT effect was particularly strong in trials in which the instrumental stimulus required inhibition of instrumental response behavior and the background CS was associated to monetary gains. Under that condition, patients performed inappropriate approach behavior, contrary to their previously formed behavioral intention. Surprisingly, the effect of alcohol and water pictures as background stimuli resembled that of aversive and appetitive CS, respectively. These findings suggest that positively valenced background CS can provoke dysfunctional instrumental approach behavior in impulsive alcohol-dependent patients. Consequently, in real life they might be easily seduced by environmental cues to engage in actions thwarting their long-term goals. Such behaviors may include, but are not limited to, approaching alcohol. Y1 - 2017 U6 - https://doi.org/10.1038/tp.2017.158 SN - 2158-3188 VL - 7 SP - 1209 EP - 1222 PB - Nature Publ. Group CY - New York ER - TY - JOUR A1 - Richter, Philipp A1 - Nuza, S. E. A1 - Fox, Andrew J. A1 - Wakker, Bart P. A1 - Lehner, N. A1 - Ben Bekhti, Nadya A1 - Fechner, Cora A1 - Wendt, Martin A1 - Howk, J. Christopher A1 - Muzahid, S. A1 - Ganguly, R. A1 - Charlton, Jane C. T1 - An HST/COS legacy survey of high-velocity ultraviolet absorption in the JF - Astronomy and astrophysics : an international weekly journal N2 - Context. The Milky Way is surrounded by large amounts of diffuse gaseous matter that connects the stellar body of our Galaxy with its large-scale Local Group (LG) environment. Aims. To characterize the absorption properties of this circumgalactic medium (CGM) and its relation to the LG we present the so-far largest survey of metal absorption in Galactic high-velocity clouds (HVCs) using archival ultraviolet (UV) spectra of extragalactic background sources. The UV data are obtained with the Cosmic Origins Spectrograph (COS) onboard the Hubble Space Telescope (HST) and are supplemented by 21 cm radio observations of neutral hydrogen. Methods. Along 270 sightlines we measure metal absorption in the lines of Si II, Si III, C II, and C IV and associated H I 21 cm emission in HVCs in the velocity range vertical bar v(LSR)vertical bar = 100-500 km s(-1). With this unprecedented large HVC sample we were able to improve the statistics on HVC covering fractions, ionization conditions, small-scale structure, CGM mass, and inflow rate. For the first time, we determine robustly the angular two point correlation function of the high-velocity absorbers, systematically analyze antipodal sightlines on the celestial sphere, and compare the HVC absorption characteristics with that of damped Lyman alpha absorbers (DLAs) and constrained cosmological simulations of the LG (CLUES project). KW - Galaxy: halo KW - Galaxy: structure KW - Galaxy: evolution KW - ISM: kinematics and dynamics KW - techniques: spectroscopic KW - ultraviolet: ISM Y1 - 2017 U6 - https://doi.org/10.1051/0004-6361/201630081 SN - 1432-0746 VL - 607 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Weyhenmeyer, Gesa A. A1 - Mackay, Murray A1 - Stockwell, Jason D. A1 - Thiery, Wim A1 - Grossart, Hans-Peter A1 - Augusto-Silva, Petala B. A1 - Baulch, Helen M. A1 - de Eyto, Elvira A1 - Hejzlar, Josef A1 - Kangur, Kuelli A1 - Kirillin, Georgiy A1 - Pierson, Don C. A1 - Rusak, James A. A1 - Sadro, Steven A1 - Woolway, R. Iestyn T1 - Citizen science shows systematic changes in the temperature difference between air and inland waters with global warming JF - Scientific reports N2 - Citizen science projects have a long history in ecological studies. The research usefulness of such projects is dependent on applying simple and standardized methods. Here, we conducted a citizen science project that involved more than 3500 Swedish high school students to examine the temperature difference between surface water and the overlying air (T-w-T-a) as a proxy for sensible heat flux (Q(H)). If Q(H) is directed upward, corresponding to positive T-w-T-a, it can enhance CO2 and CH4 emissions from inland waters, thereby contributing to increased greenhouse gas concentrations in the atmosphere. The students found mostly negative T-w-T-a across small ponds, lakes, streams/rivers and the sea shore (i.e. downward Q(H)), with T-w-T-a becoming increasingly negative with increasing T-a. Further examination of T-w-T-a using high-frequency temperature data from inland waters across the globe confirmed that T-w-T-a is linearly related to T-a. Using the longest available high-frequency temperature time series from Lake Erken, Sweden, we found a rapid increase in the occasions of negative T-w-T-a with increasing annual mean T-a since 1989. From these results, we can expect that ongoing and projected global warming will result in increasingly negative T-w-T-a, thereby reducing CO2 and CH4 transfer velocities from inland waters into the atmosphere. Y1 - 2017 U6 - https://doi.org/10.1038/srep43890 SN - 2045-2322 VL - 7 PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Ferrera, Isabel A1 - Sarmento, Hugo A1 - Priscu, John C. A1 - Chiuchiolo, Amy A1 - Gonzalez, Jose M. A1 - Grossart, Hans-Peter T1 - Diversity and Distribution of Freshwater Aerobic Anoxygenic Phototrophic Bacteria across a Wide Latitudinal Gradient JF - Frontiers in microbiology N2 - Aerobic anoxygenic phototrophs (AAPs) have been shown to exist in numerous marine and brackish environments where they are hypothesized to play important ecological roles. Despite their potential significance, the study of freshwater AAPs is in its infancy and limited to local investigations. Here, we explore the occurrence, diversity and distribution of AAPs in lakes covering a wide latitudinal gradient: Mongolian and German lakes located in temperate regions of Eurasia, tropical Great East African lakes, and polar permanently ice-covered Antarctic lakes. Our results show a widespread distribution of AAPs in lakes with contrasting environmental conditions and confirm that this group is composed of different members of the Alpha- and Betaproteobacteria. While latitude does not seem to strongly influence AAP abundance, clear patterns of community structure and composition along geographic regions were observed as indicated by a strong macro-geographical signal in the taxonomical composition of AAPs. Overall, our results suggest that the distribution patterns of freshwater AAPs are likely driven by a combination of small-scale environmental conditions (specific of each lake and region) and large-scale geographic factors (climatic regions across a latitudinal gradient). KW - AAP bacteria KW - photoheterotrophy KW - pufM gene KW - freshwater lakes KW - latitudinal gradients KW - biogeography Y1 - 2017 U6 - https://doi.org/10.3389/fmicb.2017.00175 SN - 1664-302X VL - 8 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Acero, F. A1 - Aloisio, R. A1 - Amans, J. A1 - Amato, Elena A1 - Antonelli, L. A. A1 - Aramo, C. A1 - Armstrong, T. A1 - Arqueros, F. A1 - Asano, Katsuaki A1 - Ashley, M. A1 - Backes, M. A1 - Balazs, C. A1 - Balzer, A. A1 - Bamba, Aya A1 - Barkov, Maxim A1 - Barrio, J. A. A1 - Benbow, Wystan A1 - Bernloehr, K. A1 - Beshley, V. A1 - Bigongiari, C. A1 - Biland, A. A1 - Bilinsky, A. A1 - Bissaldi, Elisabetta A1 - Biteau, J. A1 - Blanch, O. A1 - Blasi, P. A1 - Blazek, J. A1 - Boisson, C. A1 - Bonanno, G. A1 - Bonardi, A. A1 - Bonavolonta, C. A1 - Bonnoli, G. A1 - Braiding, C. A1 - Brau-Nogue, S. A1 - Bregeon, J. A1 - Brown, A. M. A1 - Bugaev, V. A1 - Bulgarelli, A. A1 - Bulik, T. A1 - Burton, Michael A1 - Burtovoi, A. A1 - Busetto, G. A1 - Bottcher, M. A1 - Cameron, R. A1 - Capalbi, M. A1 - Caproni, Anderson A1 - Caraveo, P. A1 - Carosi, R. A1 - Cascone, E. A1 - Cerruti, M. A1 - Chaty, Sylvain A1 - Chen, A. A1 - Chen, X. A1 - Chernyakova, M. A1 - Chikawa, M. A1 - Chudoba, J. A1 - Cohen-Tanugi, J. A1 - Colafrancesco, S. A1 - Conforti, V. A1 - Contreras, J. L. A1 - Costa, A. A1 - Cotter, G. A1 - Covino, Stefano A1 - Covone, G. A1 - Cumani, P. A1 - Cusumano, G. A1 - Daniel, M. A1 - Dazzi, F. A1 - De Angelis, A. A1 - De Cesare, G. A1 - De Franco, A. A1 - De Frondat, F. A1 - Dal Pino, E. M. de Gouveia A1 - De Lisio, C. A1 - Lopez, R. de los Reyes A1 - De Lotto, B. A1 - de Naurois, M. A1 - De Palma, F. A1 - Del Santo, M. A1 - Delgado, C. A1 - della Volpe, D. A1 - Di Girolamo, T. A1 - Di Giulio, C. A1 - Di Pierro, F. A1 - Di Venere, L. A1 - Doro, M. A1 - Dournaux, J. A1 - Dumas, D. A1 - Dwarkadas, Vikram V. A1 - Diaz, C. A1 - Ebr, J. A1 - Egberts, Kathrin A1 - Einecke, S. A1 - Elsaesser, D. A1 - Eschbach, S. A1 - Falceta-Goncalves, D. A1 - Fasola, G. A1 - Fedorova, E. A1 - Fernandez-Barral, A. A1 - Ferrand, Gilles A1 - Fesquet, M. A1 - Fiandrini, E. A1 - Fiasson, A. A1 - Filipovic, Miroslav D. A1 - Fioretti, V. A1 - Font, L. A1 - Fontaine, Gilles A1 - Franco, F. J. A1 - Freixas Coromina, L. A1 - Fujita, Yutaka A1 - Fukui, Y. A1 - Funk, S. A1 - Forster, A. A1 - Gadola, A. A1 - Lopez, R. Garcia A1 - Garczarczyk, M. A1 - Giglietto, N. A1 - Giordano, F. A1 - Giuliani, A. A1 - Glicenstein, J. A1 - Gnatyk, R. A1 - Goldoni, P. A1 - Grabarczyk, T. A1 - Graciani, R. A1 - Graham, J. A1 - Grandi, P. A1 - Granot, Jonathan A1 - Green, A. J. A1 - Griffiths, S. A1 - Gunji, S. A1 - Hakobyan, H. A1 - Hara, S. A1 - Hassan, T. A1 - Hayashida, M. A1 - Heller, M. A1 - Helo, J. C. A1 - Hinton, J. A1 - Hnatyk, B. A1 - Huet, J. A1 - Huetten, M. A1 - Humensky, T. B. A1 - Hussein, M. A1 - Horandel, J. A1 - Ikeno, Y. A1 - Inada, T. A1 - Inome, Y. A1 - Inoue, S. A1 - Inoue, T. A1 - Inoue, Y. A1 - Ioka, K. A1 - Iori, Maurizio A1 - Jacquemier, J. A1 - Janecek, P. A1 - Jankowsky, D. A1 - Jung, I. A1 - Kaaret, P. A1 - Katagiri, H. A1 - Kimeswenger, S. A1 - Kimura, Shigeo S. A1 - Knodlseder, J. A1 - Koch, B. A1 - Kocot, J. A1 - Kohri, K. A1 - Komin, N. A1 - Konno, Y. A1 - Kosack, K. A1 - Koyama, S. A1 - Kraus, Michaela A1 - Kubo, Hidetoshi A1 - Mezek, G. Kukec A1 - Kushida, J. A1 - La Palombara, N. A1 - Lalik, K. A1 - Lamanna, G. A1 - Landt, H. A1 - Lapington, J. A1 - Laporte, P. A1 - Lee, S. A1 - Lees, J. A1 - Lefaucheur, J. A1 - Lenain, J. -P. A1 - Leto, Giuseppe A1 - Lindfors, E. A1 - Lohse, T. A1 - Lombardi, S. A1 - Longo, F. A1 - Lopez, M. A1 - Lucarelli, F. A1 - Luque-Escamilla, Pedro Luis A1 - Lopez-Coto, R. A1 - Maccarone, M. C. A1 - Maier, G. A1 - Malaguti, G. A1 - Mandat, D. A1 - Maneva, G. A1 - Mangano, S. A1 - Marcowith, Alexandre A1 - Marti, J. A1 - Martinez, M. A1 - Martinez, G. A1 - Masuda, S. A1 - Maurin, G. A1 - Maxted, N. A1 - Melioli, Claudio A1 - Mineo, T. A1 - Mirabal, N. A1 - Mizuno, T. A1 - Moderski, R. A1 - Mohammed, M. A1 - Montaruli, T. A1 - Moralejo, A. A1 - Mori, K. A1 - Morlino, G. A1 - Morselli, A. A1 - Moulin, Emmanuel A1 - Mukherjee, R. A1 - Mundell, C. A1 - Muraishi, H. A1 - Murase, Kohta A1 - Nagataki, Shigehiro A1 - Nagayoshi, T. A1 - Naito, T. A1 - Nakajima, D. A1 - Nakamori, T. A1 - Nemmen, R. A1 - Niemiec, Jacek A1 - Nieto, D. A1 - Nievas-Rosillo, M. A1 - Nikolajuk, M. A1 - Nishijima, K. A1 - Noda, K. A1 - Nogues, L. A1 - Nosek, D. A1 - Novosyadlyj, B. A1 - Nozaki, S. A1 - Ohira, Yutaka A1 - Ohishi, M. A1 - Ohm, S. A1 - Okumura, A. A1 - Ong, R. A. A1 - Orito, R. A1 - Orlati, A. A1 - Ostrowski, M. A1 - Oya, I. A1 - Padovani, Marco A1 - Palacio, J. A1 - Palatka, M. A1 - Paredes, Josep M. A1 - Pavy, S. A1 - Persic, M. A1 - Petrucci, P. A1 - Petruk, Oleh A1 - Pisarski, A. A1 - Pohl, Martin A1 - Porcelli, A. A1 - Prandini, E. A1 - Prast, J. A1 - Principe, G. A1 - Prouza, M. A1 - Pueschel, Elisa A1 - Puelhofer, G. A1 - Quirrenbach, A. A1 - Rameez, M. A1 - Reimer, O. A1 - Renaud, M. A1 - Ribo, M. A1 - Rico, J. A1 - Rizi, V. A1 - Rodriguez, J. A1 - Fernandez, G. Rodriguez A1 - Rodriguez Vazquez, J. J. A1 - Romano, Patrizia A1 - Romeo, G. A1 - Rosado, J. A1 - Rousselle, J. A1 - Rowell, G. A1 - Rudak, B. A1 - Sadeh, I. A1 - Safi-Harb, S. A1 - Saito, T. A1 - Sakaki, N. A1 - Sanchez, D. A1 - Sangiorgi, P. A1 - Sano, H. A1 - Santander, M. A1 - Sarkar, S. A1 - Sawada, M. A1 - Schioppa, E. J. A1 - Schoorlemmer, H. A1 - Schovanek, P. A1 - Schussler, F. A1 - Sergijenko, O. A1 - Servillat, M. A1 - Shalchi, A. A1 - Shellard, R. C. A1 - Siejkowski, H. A1 - Sillanpaa, A. A1 - Simone, D. A1 - Sliusar, V. A1 - Sol, H. A1 - Stanic, S. A1 - Starling, R. A1 - Stawarz, L. A1 - Stefanik, S. A1 - Stephan, M. A1 - Stolarczyk, T. A1 - Szanecki, M. A1 - Szepieniec, T. A1 - Tagliaferri, G. A1 - Tajima, H. A1 - Takahashi, M. A1 - Takeda, J. A1 - Tanaka, M. A1 - Tanaka, S. A1 - Tejedor, L. A. A1 - Telezhinsky, Igor O. A1 - Temnikov, P. A1 - Terada, Y. A1 - Tescaro, D. A1 - Teshima, M. A1 - Testa, V. A1 - Thoudam, S. A1 - Tokanai, F. A1 - Torres, D. F. A1 - Torresi, E. A1 - Tosti, G. A1 - Townsley, C. A1 - Travnicek, P. A1 - Trichard, C. A1 - Trifoglio, M. A1 - Tsujimoto, S. A1 - Vagelli, V. A1 - Vallania, P. A1 - Valore, L. A1 - van Driel, W. A1 - van Eldik, C. A1 - Vandenbroucke, Justin A1 - Vassiliev, V. A1 - Vecchi, M. A1 - Vercellone, Stefano A1 - Vergani, S. A1 - Vigorito, C. A1 - Vorobiov, S. A1 - Vrastil, M. A1 - Vazquez Acosta, M. L. A1 - Wagner, S. J. A1 - Wagner, R. A1 - Wakely, S. P. A1 - Walter, R. A1 - Ward, J. E. A1 - Watson, J. J. A1 - Weinstein, A. A1 - White, M. A1 - White, R. A1 - Wierzcholska, A. A1 - Wilcox, P. A1 - Williams, D. A. A1 - Wischnewski, R. A1 - Wojcik, P. A1 - Yamamoto, T. A1 - Yamamoto, H. A1 - Yamazaki, Ryo A1 - Yanagita, S. A1 - Yang, L. A1 - Yoshida, T. A1 - Yoshida, M. A1 - Yoshiike, S. A1 - Yoshikoshi, T. A1 - Zacharias, M. A1 - Zampieri, L. A1 - Zanin, R. A1 - Zavrtanik, M. A1 - Zavrtanik, D. A1 - Zdziarski, A. A1 - Zech, Alraune A1 - Zechlin, Hannes A1 - Zhdanov, V. A1 - Ziegler, A. A1 - Zorn, J. T1 - Prospects for Cherenkov Telescope Array Observations of the Young Supernova Remnant RX J1713.7-3946 JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - We perform simulations for future Cherenkov Telescope Array (CTA) observations of RX J1713.7-3946, a young supernova remnant (SNR) and one of the brightest sources ever discovered in very high energy (VHE) gamma rays. Special attention is paid to exploring possible spatial (anti) correlations of gamma rays with emission at other wavelengths, in particular X-rays and CO/H I emission. We present a series of simulated images of RX J1713.7-3946 for CTA based on a set of observationally motivated models for the gamma-ray emission. In these models, VHE gamma rays produced by high-energy electrons are assumed to trace the nonthermal X-ray emission observed by XMM-Newton, whereas those originating from relativistic protons delineate the local gas distributions. The local atomic and molecular gas distributions are deduced by the NANTEN team from CO and H I observations. Our primary goal is to show how one can distinguish the emission mechanism(s) of the gamma rays (i.e., hadronic versus leptonic, or a mixture of the two) through information provided by their spatial distribution, spectra, and time variation. This work is the first attempt to quantitatively evaluate the capabilities of CTA to achieve various proposed scientific goals by observing this important cosmic particle accelerator. KW - cosmic rays KW - gamma rays: ISM KW - ISM: individual objects (RX J1713.7-3946, G347.3-0.5) Y1 - 2017 U6 - https://doi.org/10.3847/1538-4357/aa6d67 SN - 0004-637X SN - 1538-4357 VL - 840 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Archambault, S. A1 - Archer, A. A1 - Benbow, Wystan A1 - Bird, Ralph A1 - Bourbeau, E. A1 - Buchovecky, M. A1 - Buckley, J. H. A1 - Bugaev, V. A1 - Cerruti, M. A1 - Connolly, M. P. A1 - Cui, W. A1 - Dwarkadas, Vikram V. A1 - Errando, M. A1 - Falcone, A. A1 - Feng, Q. A1 - Finley, J. P. A1 - Fleischhack, H. A1 - Fortson, L. A1 - Furniss, A. A1 - Griffin, S. A1 - Huetten, M. A1 - Hanna, D. A1 - Holder, J. A1 - Johnson, C. A. A1 - Kaaret, P. A1 - Kar, P. A1 - Kelley-Hoskins, N. A1 - Kertzman, M. A1 - Kieda, D. A1 - Krause, M. A1 - Kumar, S. A1 - Lang, M. J. A1 - Maier, G. A1 - McArthur, S. A1 - McCann, A. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Nieto, D. A1 - Ong, R. A. A1 - Otte, A. N. A1 - Park, Nahee A1 - Pohl, Martin A1 - Popkow, A. A1 - Pueschel, Elisa A1 - Quinn, J. A1 - Ragan, K. A1 - Reynolds, P. T. A1 - Richards, G. T. A1 - Roache, E. A1 - Sadeh, I. A1 - Santander, M. A1 - Sembroski, G. H. A1 - Shahinyan, K. A1 - Slane, P. A1 - Staszak, D. A1 - Telezhinsky, Igor O. A1 - Trepanier, S. A1 - Tyler, J. A1 - Wakely, S. P. A1 - Weinstein, A. A1 - Weisgarber, T. A1 - Wilcox, P. A1 - Wilhelm, Alina A1 - Williams, D. A. A1 - Zitzer, B. T1 - Gamma-ray Observations of Tycho's Supernova Remnant with VERITAS and Fermi JF - The astrophysical journal : an international review of spectroscopy and astronomical physics KW - material KW - data behind figure Y1 - 2017 U6 - https://doi.org/10.3847/1538-4357/836/1/23 SN - 0004-637X SN - 1538-4357 VL - 836 IS - 1 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Archambault, S. A1 - Archer, A. A1 - Benbow, W. A1 - Bird, Ralph A1 - Bourbeau, E. A1 - Bouvier, A. A1 - Buchovecky, M. A1 - Bugaev, V. A1 - Cardenzana, J. V. A1 - Cerruti, M. A1 - Ciupik, L. A1 - Connolly, M. P. A1 - Cui, W. A1 - Daniel, M. K. A1 - Errando, M. A1 - Falcone, A. A1 - Feng, Q. A1 - Finley, J. P. A1 - Fleischhack, H. A1 - Fortson, L. A1 - Furniss, A. A1 - Gillanders, G. H. A1 - Griffin, S. A1 - Hanna, D. A1 - Hervet, O. A1 - Holder, J. A1 - Hughes, G. A1 - Humensky, T. B. A1 - Hutten, M. A1 - Johnson, C. A. A1 - Kaaret, P. A1 - Kar, P. A1 - Kertzman, M. A1 - Kieda, D. A1 - Krause, M. A1 - Lang, M. J. A1 - Lin, T. T. Y. A1 - Maier, G. A1 - McArthur, S. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Nieto, D. A1 - Ong, R. A. A1 - Otte, A. N. A1 - Park, N. A1 - Pohl, Martin A1 - Popkow, A. A1 - Pueschel, Elisa A1 - Quinn, J. A1 - Ragan, K. A1 - Reynolds, P. T. A1 - Richards, G. T. A1 - Roache, E. A1 - Rulten, C. A1 - Sadeh, I. A1 - Sembroski, G. H. A1 - Shahinyan, K. A1 - Staszak, D. A1 - Telezhinsky, Igor O. A1 - Trepanier, S. A1 - Wakely, S. P. A1 - Weinstein, A. A1 - Wilcox, P. A1 - Williams, D. A. A1 - Zitzer, B. T1 - Gamma-ray observations under bright moonlight with VERITAS JF - Astroparticle physics N2 - Imaging atmospheric Cherenkov telescopes (IACTs) are equipped with sensitive photomultiplier tube (PMT) cameras. Exposure to high levels of background illumination degrades the efficiency of and potentially destroys these photo-detectors over time, so IACTs cannot be operated in the same configuration in the presence of bright moonlight as under dark skies. Since September 2012, observations have been carried out with the VERITAS IACTs under bright moonlight (defined as about three times the night-sky-background (NSB) of a dark extragalactic field, typically occurring when Moon illumination > 35%) in two observing modes, firstly by reducing the voltage applied to the PMTs and, secondly, with the addition of ultra-violet (UV) bandpass filters to the cameras. This has allowed observations at up to about 30 times previous NSB levels (around 80% Moon illumination), resulting in 30% more observing time between the two modes over the course of a year. These additional observations have already allowed for the detection of a flare from the 1ES 1727 + 502 and for an observing program targeting a measurement of the cosmic-ray positron fraction. We provide details of these new observing modes and their performance relative to the standard VERITAS observations. (C) 2017 Elsevier B.V. All rights reserved. KW - Instrumentation KW - Moonlight KW - Observing methods KW - VERITAS KW - IACT Y1 - 2017 U6 - https://doi.org/10.1016/j.astropartphys.2017.03.001 SN - 0927-6505 SN - 1873-2852 VL - 91 SP - 34 EP - 43 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Abeysekara, A. U. A1 - Archambault, S. A1 - Archer, A. A1 - Benbow, W. A1 - Bird, R. A1 - Brose, Robert A1 - Buchovecky, M. A1 - Buckley, J. H. A1 - Bugaev, V. A1 - Cerruti, M. A1 - Connolly, M. P. A1 - Cui, W. A1 - Falcone, A. A1 - Feng, Q. A1 - Finley, J. P. A1 - Fleischhack, H. A1 - Fortson, L. A1 - Furniss, A. A1 - Gillanders, G. H. A1 - Griffin, S. A1 - Grube, J. A1 - Huetten, M. A1 - Hanna, D. A1 - Hervet, O. A1 - Holder, J. A1 - Humensky, T. B. A1 - Johnson, C. A. A1 - Kaaret, P. A1 - Kar, P. A1 - Kelley-Hoskins, N. A1 - Kertzman, M. A1 - Kieda, D. A1 - Krause, M. A1 - Krennrich, F. A1 - Kumar, S. A1 - Lang, M. J. A1 - Maier, G. A1 - McArthur, S. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Nieto, D. A1 - Ong, R. A. A1 - Otte, A. N. A1 - Park, N. A1 - Petrashyk, A. A1 - Pohl, Martin A1 - Popkow, A. A1 - Pueschel, Elisa A1 - Quinn, J. A1 - Ragan, K. A1 - Reynolds, P. T. A1 - Richards, G. T. A1 - Roache, E. A1 - Rulten, C. A1 - Sadeh, I. A1 - Santander, M. A1 - Sembroski, G. H. A1 - Shahinyan, K. A1 - Staszak, D. A1 - Telezhinsky, Igor O. A1 - Tyler, J. A1 - Vassiliev, V. V. A1 - Wakely, S. P. A1 - Weiner, O. M. A1 - Weinstein, A. A1 - Wilcox, P. A1 - Wilhelm, Alina A1 - Williams, D. A. A1 - Zitzer, B. T1 - Discovery of Very-high-energy Emission from RGB J2243+203 and Derivation of Its Redshift Upper Limit JF - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Supplement series N2 - Very-high-energy (VHE; > 100 GeV) gamma-ray emission from the blazar RGB J2243+203 was discovered with the VERITAS Cherenkov telescope array, during the period between 2014 December 21 and 24. The VERITAS energy spectrum from this source can be fitted by a power law with a photon index of 4.6 +/- 0.5, and a flux normalization at 0.15 TeV of (6.3 +/- 1.1) x 10(-10) cm(-2) s(-1) TeV-1. The integrated Fermi-LAT flux from 1 to 100 GeV during the VERITAS detection is (4.1 +/- 0.8) x 10(-8) cm(-2) s(-1), which is an order of magnitude larger than the four-year-averaged flux in the same energy range reported in the 3FGL catalog, (4.0 +/- 0.1 x 10(-9) cm(-2) s(-1)). The detection with VERITAS triggered observations in the X-ray band with the Swift-XRT. However, due to scheduling constraints Swift-XRT observations were performed 67 hr after the VERITAS detection, rather than simultaneously with the VERITAS observations. The observed X-ray energy spectrum between 2 and 10 keV can be fitted with a power law with a spectral index of 2.7 +/- 0.2, and the integrated photon flux in the same energy band is (3.6 +/- 0.6) x 10(-13) cm(-2) s(-1). EBL-model-dependent upper limits of the blazar redshift have been derived. Depending on the EBL model used, the upper limit varies in the range from z < 0.9 to z < 1.1. KW - galaxies: individual (RGB J2243+203) Y1 - 2017 U6 - https://doi.org/10.3847/1538-4365/aa8d76 SN - 0067-0049 SN - 1538-4365 VL - 233 SP - 1188 EP - 1204 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Stillfried, Milena A1 - Fickel, Jörns A1 - Börner, Konstantin A1 - Wittstatt, Ulrich A1 - Heddergott, Mike A1 - Ortmann, Sylvia A1 - Kramer-Schadt, Stephanie A1 - Frantz, Alain C. T1 - Do cities represent sources, sinks or isolated islands for urban wild boar population structure? JF - Journal of applied ecology : an official journal of the British Ecological Society KW - baps KW - Berlin KW - diyabc KW - human-wildlife conflict KW - hunting KW - microsatellites KW - movement barrier KW - source-sink dynamics KW - structure KW - urban ecology Y1 - 2017 U6 - https://doi.org/10.1111/1365-2664.12756 SN - 0021-8901 SN - 1365-2664 VL - 54 IS - 1 SP - 272 EP - 281 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Behm, David George A1 - Young, James D. A1 - Whitten, Joseph H. D. A1 - Reid, Jonathan C. A1 - Quigley, Patrick J. A1 - Low, Jonathan A1 - Li, Yimeng A1 - Lima, Camila D. A1 - Hodgson, Daniel D. A1 - Chaouachi, Anis A1 - Prieske, Olaf A1 - Granacher, Urs T1 - Effectiveness of Traditional Strength vs. Power Training on Muscle Strength, Power and Speed with Youth: A Systematic Review and Meta-Analysis JF - Frontiers in physiology N2 - Numerous national associations and multiple reviews have documented the safety and efficacy of strength training for children and adolescents. The literature highlights the significant training-induced increases in strength associated with youth strength training. However, the effectiveness of youth strength training programs to improve power measures is not as clear. This discrepancy may be related to training and testing specificity. Most prior youth strength training programs emphasized lower intensity resistance with relatively slow movements. Since power activities typically involve higher intensity, explosive-like contractions with higher angular velocities (e.g., plyometrics), there is a conflict between the training medium and testing measures. This meta-analysis compared strength (e.g., training with resistance or body mass) and power training programs (e.g., plyometric training) on proxies of muscle strength, power, and speed. A systematic literature search using a Boolean Search Strategy was conducted in the electronic databases PubMed, SPORT Discus, Web of Science, and Google Scholar and revealed 652 hits. After perusal of title, abstract, and full text, 107 studies were eligible for inclusion in this systematic review and meta-analysis. The meta-analysis showed small to moderate magnitude changes for training specificity with jump measures. In other words, power training was more effective than strength training for improving youth jump height. For sprint measures, strength training was more effective than power training with youth. Furthermore, strength training exhibited consistently large magnitude changes to lower body strength measures, which contrasted with the generally trivial, small and moderate magnitude training improvements of power training upon lower body strength, sprint and jump measures, respectively. Maturity related inadequacies in eccentric strength and balance might influence the lack of training specificity with the unilateral landings and propulsions associated with sprinting. Based on this meta-analysis, strength training should be incorporated prior to power training in order to establish an adequate foundation of strength for power training activities. KW - children KW - boys KW - girls KW - plyometric training KW - resistance training Y1 - 2017 U6 - https://doi.org/10.3389/fphys.2017.00423 SN - 1664-042X VL - 8 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Ran, Niva A. A1 - Roland, Steffen A1 - Love, John A. A1 - Savikhin, Victoria A1 - Takacs, Christopher J. A1 - Fu, Yao-Tsung A1 - Li, Hong A1 - Coropceanu, Veaceslav A1 - Liu, Xiaofeng A1 - Bredas, Jean-Luc A1 - Bazan, Guillermo C. A1 - Toney, Michael F. A1 - Neher, Dieter A1 - Thuc-Quyen Nguyen, T1 - Impact of interfacial molecular orientation on radiative recombination and charge generation efficiency JF - Nature Communications N2 - A long standing question in organic electronics concerns the effects of molecular orientation at donor/acceptor heterojunctions. Given a well-controlled donor/acceptor bilayer system, we uncover the genuine effects of molecular orientation on charge generation and recombination. These effects are studied through the point of view of photovoltaics-however, the results have important implications on the operation of all optoelectronic devices with donor/ acceptor interfaces, such as light emitting diodes and photodetectors. Our findings can be summarized by two points. First, devices with donor molecules face-on to the acceptor interface have a higher charge transfer state energy and less non-radiative recombination, resulting in larger open-circuit voltages and higher radiative efficiencies. Second, devices with donor molecules edge-on to the acceptor interface are more efficient at charge generation, attributed to smaller electronic coupling between the charge transfer states and the ground state, and lower activation energy for charge generation. Y1 - 2017 U6 - https://doi.org/10.1038/s41467-017-00107-4 SN - 2041-1723 VL - 8 PB - Nature Publ. Group CY - London ER - TY - JOUR A1 - Bjorneras, C. A1 - Weyhenmeyer, G. A. A1 - Evans, C. D. A1 - Gessner, M. O. A1 - Großart, Hans-Peter A1 - Kangur, K. A1 - Kokorite, I. A1 - Kortelainen, P. A1 - Laudon, H. A1 - Lehtoranta, J. A1 - Lottig, N. A1 - Monteith, D. T. A1 - Noges, P. A1 - Noges, T. A1 - Oulehle, F. A1 - Riise, G. A1 - Rusak, J. A. A1 - Raike, A. A1 - Sire, J. A1 - Sterling, S. A1 - Kritzberg, E. S. T1 - Widespread Increases in Iron Concentration in European and North American Freshwaters JF - Global biogeochemical cycles N2 - Recent reports of increasing iron (Fe) concentrations in freshwaters are of concern, given the fundamental role of Fe in biogeochemical processes. Still, little is known about the frequency and geographical distribution of Fe trends or about the underlying drivers. We analyzed temporal trends of Fe concentrations across 340 water bodies distributed over 10 countries in northern Europe and North America in order to gain a clearer understanding of where, to what extent, and why Fe concentrations are on the rise. We found that Fe concentrations have significantly increased in 28% of sites, and decreased in 4%, with most positive trends located in northern Europe. Regions with rising Fe concentrations tend to coincide with those with organic carbon (OC) increases. Fe and OC increases may not be directly mechanistically linked, but may nevertheless be responding to common regional-scale drivers such as declining sulfur deposition or hydrological changes. A role of hydrological factors was supported by covarying trends in Fe and dissolved silica, as these elements tend to stem from similar soil depths. A positive relationship between Fe increases and conifer cover suggests that changing land use and expanded forestry could have contributed to enhanced Fe export, although increases were also observed in nonforested areas. We conclude that the phenomenon of increasing Fe concentrations is widespread, especially in northern Europe, with potentially significant implications for wider ecosystem biogeochemistry, and for the current browning of freshwaters. Y1 - 2017 U6 - https://doi.org/10.1002/2017GB005749 SN - 0886-6236 SN - 1944-9224 VL - 31 SP - 1488 EP - 1500 PB - American Geophysical Union CY - Washington ER - TY - GEN A1 - Aich, Valentin A1 - Liersch, Stefan A1 - Vetter, Tobias A1 - Andersson, Jafet C. M. A1 - Müller, Eva Nora A1 - Hattermann, Fred T1 - Climate or land use? BT - Attribution of changes in river flooding in the Sahel Zone N2 - This study intends to contribute to the ongoing discussion on whether land use and land cover changes (LULC) or climate trends have the major influence on the observed increase of flood magnitudes in the Sahel. A simulation-based approach is used for attributing the observed trends to the postulated drivers. For this purpose, the ecohydrological model SWIM (Soil and Water Integrated Model) with a new, dynamic LULC module was set up for the Sahelian part of the Niger River until Niamey, including the main tributaries Sirba and Goroul. The model was driven with observed, reanalyzed climate and LULC data for the years 1950–2009. In order to quantify the shares of influence, one simulation was carried out with constant land cover as of 1950, and one including LULC. As quantitative measure, the gradients of the simulated trends were compared to the observed trend. The modeling studies showed that for the Sirba River only the simulation which included LULC was able to reproduce the observed trend. The simulation without LULC showed a positive trend for flood magnitudes, but underestimated the trend significantly. For the Goroul River and the local flood of the Niger River at Niamey, the simulations were only partly able to reproduce the observed trend. In conclusion, the new LULC module enabled some first quantitative insights into the relative influence of LULC and climatic changes. For the Sirba catchment, the results imply that LULC and climatic changes contribute in roughly equal shares to the observed increase in flooding. For the other parts of the subcatchment, the results are less clear but show, that climatic changes and LULC are drivers for the flood increase; however their shares cannot be quantified. Based on these modeling results, we argue for a two-pillar adaptation strategy to reduce current and future flood risk: Flood mitigation for reducing LULC-induced flood increase, and flood adaptation for a general reduction of flood vulnerability. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 345 KW - simulation-based attribution KW - Sahel KW - Niger River KW - climate variability KW - hydrological modeling KW - flood mitigation KW - flood adaptation Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-400115 ER - TY - THES A1 - Lachmann, Sabrina C. T1 - Ecophysiology matters: Inorganic carbon acquisition in green microalgae related to different nutrient conditions Y1 - 2017 ER - TY - JOUR A1 - De Angelis, A. A1 - Tatischeff, V. A1 - Tavani, M. A1 - Oberlack, U. A1 - Grenier, I. A1 - Hanloni, L. A1 - Walter, R. A1 - Argan, A. A1 - Von Ballmoos, P. A1 - Bulgarelli, A. A1 - Donnarumma, I. A1 - Hernanz, M. A1 - Kuvvetli, I. A1 - Pearce, M. A1 - Zdziarski, A. A1 - Aboudan, A. A1 - Ajello, M. A1 - Ambrosi, G. A1 - Bernard, D. A1 - Bernardini, E. A1 - Bonvicini, V. A1 - Brogna, A. A1 - Branchesi, M. A1 - Budtz-Jorgensen, C. A1 - Bykov, A. M. A1 - Campana, R. A1 - Cardillo, M. A1 - Coppi, P. A1 - De Martino, D. A1 - Diehl, R. A1 - Doro, M. A1 - Fioretti, V. A1 - Funk, S. A1 - Ghisellini, G. A1 - Grove, E. A1 - Hamadache, C. A1 - Hartmann, D. H. A1 - Hayashida, M. A1 - Isern, J. A1 - Kanbach, G. A1 - Kiener, J. A1 - Knodlseder, J. A1 - Labanti, C. A1 - Laurent, P. A1 - Limousin, O. A1 - Longo, F. A1 - Mannheim, K. A1 - Marisaldi, M. A1 - Martinez, M. A1 - Mazziotta, Mario Nicola A1 - McEnery, J. A1 - Mereghetti, S. A1 - Minervini, G. A1 - Moiseev, A. A1 - Morselli, A. A1 - Nakazawa, K. A1 - Orleanski, P. A1 - Paredes, J. M. A1 - Patricelli, B. A1 - Pevre, J. A1 - Piano, G. A1 - Pohl, Martin A1 - Ramarijaona, H. A1 - Rando, R. A1 - Reichardt, I. A1 - Roncadelli, M. A1 - Silva, R. A1 - Tavecchio, F. A1 - Thompson, D. J. A1 - Turolla, R. A1 - Ulyanov, A. A1 - Vacchi, A. A1 - Wu, X. A1 - Zoglauer, A. T1 - The e-ASTROGAM mission Exploring the extreme Universe with gamma rays in the MeV - GeV range JF - Experimental astronomy : an international journal on astronomical instrumentation and data analysis N2 - e-ASTROGAM (‘enhanced ASTROGAM’) is a breakthrough Observatory space mission, with a detector composed by a Silicon tracker, a calorimeter, and an anticoincidence system, dedicated to the study of the non-thermal Universe in the photon energy range from 0.3 MeV to 3 GeV – the lower energy limit can be pushed to energies as low as 150 keV, albeit with rapidly degrading angular resolution, for the tracker, and to 30 keV for calorimetric detection. The mission is based on an advanced space-proven detector technology, with unprecedented sensitivity, angular and energy resolution, combined with polarimetric capability. Thanks to its performance in the MeV-GeV domain, substantially improving its predecessors, e-ASTROGAM will open a new window on the non-thermal Universe, making pioneering observations of the most powerful Galactic and extragalactic sources, elucidating the nature of their relativistic outflows and their effects on the surroundings. With a line sensitivity in the MeV energy range one to two orders of magnitude better than previous generation instruments, e-ASTROGAM will determine the origin of key isotopes fundamental for the understanding of supernova explosion and the chemical evolution of our Galaxy. The mission will provide unique data of significant interest to a broad astronomical community, complementary to powerful observatories such as LIGO-Virgo-GEO600-KAGRA, SKA, ALMA, E-ELT, TMT, LSST, JWST, Athena, CTA, IceCube, KM3NeT, and the promise of eLISA. KW - High-Energy Gamma-Ray Astronomy KW - High-Energy Astrophysics KW - Nuclear Astrophysics KW - Compton and Pair Creation Telescope KW - Gamma-Ray Bursts KW - Active Galactic Nuclei KW - Jets KW - Outflows KW - Multiwavelength Observations of the Universe KW - Counterparts of gravitational waves KW - Fermi KW - Dark Matter KW - Nucleosynthesis KW - Early Universe KW - Supernovae KW - Cosmic Rays KW - Cosmic Antimatter Y1 - 2017 U6 - https://doi.org/10.1007/s10686-017-9533-6 SN - 0922-6435 SN - 1572-9508 VL - 44 SP - 25 EP - 82 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Chang, D. -C. A1 - Schulze, Bert-Wolfgang T1 - Calculus on spaces with higher singularities JF - Journal of pseudo-differential operators and applications N2 - We establish extensions of the standard pseudo-differential calculus to specific classes of operators with operator-valued symbols occurring in symbolic hierarchies motivated by manifolds with higher singularities or stratified spaces. KW - Pseudo-differential operators KW - Operator-valued symbols KW - Fourier and Mellin transform Y1 - 2017 U6 - https://doi.org/10.1007/s11868-016-0180-x SN - 1662-9981 SN - 1662-999X VL - 8 SP - 585 EP - 622 PB - Springer CY - Basel ER - TY - JOUR A1 - Patel, Riddhi P. A1 - Lenz, Dorina A1 - Kitchener, Andrew C. A1 - Fickel, Jorns A1 - Foerster, Daniel W. A1 - Wilting, Andreas T1 - Threatened but understudied: supporting conservation by understanding the genetic structure of the flat-headed cat JF - Conservation genetics KW - Flat-headed cat KW - Habitat specialist KW - Hybrid capture KW - Mitogenome KW - MtDNA Y1 - 2017 U6 - https://doi.org/10.1007/s10592-017-0990-2 SN - 1566-0621 SN - 1572-9737 VL - 18 SP - 1423 EP - 1433 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Allen, C. A1 - Archambault, S. A1 - Archer, A. A1 - Benbow, W. A1 - Bird, R. A1 - Bourbeau, E. A1 - Brose, Robert A1 - Buchovecky, M. A1 - Buckley, J. H. A1 - Bugaev, V. A1 - Cardenzana, J. V. A1 - Cerruti, M. A1 - Chen, Xuhui A1 - Christiansen, J. L. A1 - Connolly, M. P. A1 - Cui, W. A1 - Daniel, M. K. A1 - Eisch, J. D. A1 - Falcone, Abe A1 - Feng, Q. A1 - Fernandez-Alonso, M. A1 - Finley, J. P. A1 - Fleischhack, H. A1 - Flinders, A. A1 - Fortson, L. A1 - Furniss, A. A1 - Gillanders, G. H. A1 - Griffin, S. A1 - Grube, J. A1 - Huetten, M. A1 - Hakansson, N. A1 - Hanna, D. A1 - Hervet, O. A1 - Holder, J. A1 - Hughes, G. A1 - Humensky, T. B. A1 - Johnson, C. A. A1 - Kaaret, P. A1 - Kar, P. A1 - Kelley-Hoskins, N. A1 - Kertzman, M. A1 - Kieda, D. A1 - Krause, M. A1 - Krennrich, F. A1 - Kumar, S. A1 - Lang, M. J. A1 - Maier, G. A1 - McArthur, S. A1 - McCann, A. A1 - Meagher, K. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Nguyen, T. A1 - Nieto, D. A1 - Ong, R. A. A1 - Otte, A. N. A1 - Park, N. A1 - Petrashyk, A. A1 - Pichel, A. A1 - Pohl, Martin A1 - Popkow, A. A1 - Pueschel, Elisa A1 - Quinn, J. A1 - Ragan, K. A1 - Reynolds, P. T. A1 - Richards, G. T. A1 - Roache, E. A1 - Rovero, A. C. A1 - Rulten, C. A1 - Sadeh, I. A1 - Santander, Marcos A1 - Sembroski, G. H. A1 - Shahinyan, K. A1 - Telezhinsky, Igor O. A1 - Tucci, J. V. A1 - Tyler, J. A1 - Wakely, S. P. A1 - Weinstein, A. A1 - Wilhelm, Alina A1 - Williams, D. A. T1 - Very-High-Energy gamma-Ray Observations of the Blazar 1ES 2344+514 with VERITAS JF - Monthly notices of the Royal Astronomical Society N2 - We present very-high-energy gamma-ray observations of the BL Lac object 1ES 2344+514 taken by the Very Energetic Radiation Imaging Telescope Array System between 2007 and 2015. 1ES 2344+514 is detected with a statistical significance above the background of 20.8 sigma in 47.2 h (livetime) of observations, making this the most comprehensive very-high-energy study of 1ES 2344+514 to date. Using these observations, the temporal properties of 1ES 2344+514 are studied on short and long times-scales. We fit a constant-flux model to nightly and seasonally binned light curves and apply a fractional variability test to determine the stability of the source on different time-scales. We reject the constant-flux model for the 2007-2008 and 2014-2015 nightly binned light curves and for the long-term seasonally binned light curve at the > 3 sigma level. The spectra of the time-averaged emission before and after correction for attenuation by the extragalactic background light are obtained. The observed time-averaged spectrum above 200 GeV is satisfactorily fitted (x(2)/NDF = 7.89/6) by a power-law function with an index Gamma = 2.46 +/- 0.06(stat) +/- 0.20(sys) and extends to at least 8 TeV. The extragalactic-backgroundlight-deabsorbed spectrum is adequately fit (x(2)/NDF = 6.73/6) by a power-law function with an index Gamma = 2.15 +/- 0.06(stat) +/- 0.20(sys) while an F-test indicates that the power law with an exponential cut-off function provides a marginally better fit (x(2)/NDF = 2.56/5) at the 2.1 sigma level. The source location is found to be consistent with the published radio location and its spatial extent is consistent with a point source. KW - astroparticle physics KW - BL Lacertae objects: individual: 1ES 2344+514=VERJ2347+517 KW - gamma-rays: galaxies Y1 - 2017 U6 - https://doi.org/10.1093/mnras/stx1756 SN - 0035-8711 SN - 1365-2966 VL - 471 SP - 2117 EP - 2123 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Abeysekara, A. U. A1 - Archambault, S. A1 - Archer, A. A1 - Benbow, Wystan A1 - Bird, Ralph A1 - Buchovecky, M. A1 - Buckley, J. H. A1 - Bugaev, V. A1 - Byrum, K. A1 - Cerruti, M. A1 - Chen, X. A1 - Ciupik, L. A1 - Cui, W. A1 - Dickinson, H. J. A1 - Eisch, J. D. A1 - Errando, M. A1 - Falcone, A. A1 - Feng, Q. A1 - Finley, J. P. A1 - Fleischhack, H. A1 - Fortson, L. A1 - Furniss, A. A1 - Gillanders, G. H. A1 - Griffin, S. A1 - Grube, J. A1 - Hutten, M. A1 - Hakansson, N. A1 - Hanna, D. A1 - Holder, J. A1 - Humensky, T. B. A1 - Johnson, C. A. A1 - Kaaret, P. A1 - Kar, P. A1 - Kertzman, M. A1 - Kieda, D. A1 - Krause, M. A1 - Krennrich, F. A1 - Kumar, S. A1 - Lang, M. J. A1 - Maier, G. A1 - McArthur, S. A1 - McCann, A. A1 - Meagher, K. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Nguyen, T. A1 - Nieto, D. A1 - Ong, R. A. A1 - Otte, A. N. A1 - Park, N. A1 - Pelassa, V. A1 - Pohl, Martin A1 - Popkow, A. A1 - Pueschel, Elisa A1 - Quinn, J. A1 - Ragan, K. A1 - Reynolds, P. T. A1 - Richards, G. T. A1 - Roache, E. A1 - Rulten, C. A1 - Santander, M. A1 - Sembroski, G. H. A1 - Shahinyan, K. A1 - Staszak, D. A1 - Telezhinsky, Igor O. A1 - Tucci, J. V. A1 - Tyler, J. A1 - Wakely, S. P. A1 - Weiner, O. M. A1 - Weinstein, A. A1 - Wilhelm, Alina A1 - Williams, D. A. A1 - Fegan, S. A1 - Giebels, B. A1 - Horan, D. A1 - Berdyugin, A. A1 - Kuan, J. A1 - Lindfors, E. A1 - Nilsson, K. A1 - Oksanen, A. A1 - Prokoph, H. A1 - Reinthal, R. A1 - Takalo, L. A1 - Zefi, F. T1 - A Luminous and Isolated Gamma-Ray Flare from the Blazar B2 1215+30 JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - B2 1215+30 is a BL-Lac-type blazar that was first detected at TeV energies by the MAGIC atmospheric Cherenkov telescopes and subsequently confirmed by the Very Energetic Radiation Imaging Telescope Array System (VERITAS) observatory with data collected between 2009 and 2012. In 2014 February 08, VERITAS detected a large-amplitude flare from B2. 1215+30 during routine monitoring observations of the blazar 1ES. 1218+304, located in the same field of view. The TeV flux reached 2.4 times the Crab Nebula flux with a variability timescale of <3.6 hr. Multiwavelength observations with Fermi-LAT, Swift, and the Tuorla Observatory revealed a correlated high GeV flux state and no significant optical counterpart to the flare, with a spectral energy distribution where the gamma-ray luminosity exceeds the synchrotron luminosity. When interpreted in the framework of a onezone leptonic model, the observed emission implies a high degree of beaming, with Doppler factor delta > 10, and an electron population with spectral index p < 2.3. KW - BL Lacertae objects: individual (B2 1215+30, VER J1217+301) KW - galaxies: active KW - galaxies: jets KW - galaxies: nuclei KW - gamma rays: galaxies Y1 - 2017 U6 - https://doi.org/10.3847/1538-4357/836/2/205 SN - 0004-637X SN - 1538-4357 VL - 836 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - GEN A1 - Sadovnichii, V. A. A1 - Panasyuk, M. I. A1 - Amelyushkin, A. M. A1 - Benghin, V. V. A1 - Garipov, G. K. A1 - Kalegaev, V. V. A1 - Klimov, P. A. A1 - Khrenov, B. A. A1 - Petrov, V. L. A1 - Sharakin, S. A. A1 - Shirokov, A. V. A1 - Svertilov, S. I. A1 - Zotov, M. Y. A1 - Yashin, I. V. A1 - Gorbovskoy, E. S. A1 - Lipunov, V. M. A1 - Park, I. H. A1 - Lee, J. A1 - Jeong, S. A1 - Kim, M. B. A1 - Jeong, H. M. A1 - Shprits, Yuri Y. A1 - Angelopoulos, V. A1 - Russell, C. T. A1 - Runov, A. A1 - Turner, D. A1 - Strangeway, R. J. A1 - Caron, R. A1 - Biktemerova, S. A1 - Grinyuk, A. A1 - Lavrova, M. A1 - Tkachev, L. A1 - Tkachenko, A. A1 - Martinez, O. A1 - Salazar, H. A1 - Ponce, E. T1 - "Lomonosov" satellite-space observatory to study extreme phenomena in space T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - The "Lomonosov" space project is lead by Lomonosov Moscow State University in collaboration with the following key partners: Joint Institute for Nuclear Research, Russia, University of California, Los Angeles (USA), University of Pueblo (Mexico), Sungkyunkwan University (Republic of Korea) and with Russian space industry organi-zations to study some of extreme phenomena in space related to astrophysics, astroparticle physics, space physics, and space biology. The primary goals of this experiment are to study: -Ultra-high energy cosmic rays (UHECR) in the energy range of the Greizen-ZatsepinKuzmin (GZK) cutoff; -Ultraviolet (UV) transient luminous events in the upper atmosphere; -Multi-wavelength study of gamma-ray bursts in visible, UV, gamma, and X-rays; -Energetic trapped and precipitated radiation (electrons and protons) at low-Earth orbit (LEO) in connection with global geomagnetic disturbances; -Multicomponent radiation doses along the orbit of spacecraft under different geomagnetic conditions and testing of space segments of optical observations of space-debris and other space objects; -Instrumental vestibular-sensor conflict of zero-gravity phenomena during space flight. This paper is directed towards the general description of both scientific goals of the project and scientific equipment on board the satellite. The following papers of this issue are devoted to detailed descriptions of scientific instruments. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 959 KW - gamma-ray bursts KW - ultra-high energy cosmic rays KW - radiation belts KW - space mission Y1 - 2020 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-428185 SN - 1866-8372 IS - 959 SP - 1705 EP - 1738 ER - TY - JOUR A1 - Kreibich, Heidi A1 - Di Baldassarre, Giuliano A1 - Vorogushyn, Sergiy A1 - Aerts, Jeroen C. J. H. A1 - Apel, Heiko A1 - Aronica, Giuseppe T. A1 - Arnbjerg-Nielsen, Karsten A1 - Bouwer, Laurens M. A1 - Bubeck, Philip A1 - Caloiero, Tommaso A1 - Chinh, Do T. A1 - Cortes, Maria A1 - Gain, Animesh K. A1 - Giampa, Vincenzo A1 - Kuhlicke, Christian A1 - Kundzewicz, Zbigniew W. A1 - Llasat, Maria Carmen A1 - Mard, Johanna A1 - Matczak, Piotr A1 - Mazzoleni, Maurizio A1 - Molinari, Daniela A1 - Dung, Nguyen V. A1 - Petrucci, Olga A1 - Schröter, Kai A1 - Slager, Kymo A1 - Thieken, Annegret A1 - Ward, Philip J. A1 - Merz, Bruno T1 - Adaptation to flood risk BT - Results of international paired flood event studies JF - Earth's Future N2 - As flood impacts are increasing in large parts of the world, understanding the primary drivers of changes in risk is essential for effective adaptation. To gain more knowledge on the basis of empirical case studies, we analyze eight paired floods, that is, consecutive flood events that occurred in the same region, with the second flood causing significantly lower damage. These success stories of risk reduction were selected across different socioeconomic and hydro-climatic contexts. The potential of societies to adapt is uncovered by describing triggered societal changes, as well as formal measures and spontaneous processes that reduced flood risk. This novel approach has the potential to build the basis for an international data collection and analysis effort to better understand and attribute changes in risk due to hydrological extremes in the framework of the IAHSs Panta Rhei initiative. Across all case studies, we find that lower damage caused by the second event was mainly due to significant reductions in vulnerability, for example, via raised risk awareness, preparedness, and improvements of organizational emergency management. Thus, vulnerability reduction plays an essential role for successful adaptation. Our work shows that there is a high potential to adapt, but there remains the challenge to stimulate measures that reduce vulnerability and risk in periods in which extreme events do not occur. KW - flooding KW - vulnerability KW - global environmental change KW - adaptation Y1 - 2017 U6 - https://doi.org/10.1002/2017EF000606 SN - 2328-4277 VL - 5 SP - 953 EP - 965 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Frenken, Thijs A1 - Alacid, Elisabet A1 - Berger, Stella A. A1 - Bourne, Elizabeth Charlotte A1 - Gerphagnon, Melanie A1 - Großart, Hans-Peter A1 - Gsell, Alena S. A1 - Ibelings, Bas W. A1 - Kagami, Maiko A1 - Kupper, Frithjof C. A1 - Letcher, Peter M. A1 - Loyau, Adeline A1 - Miki, Takeshi A1 - Nejstgaard, Jens C. A1 - Rasconi, Serena A1 - Rene, Albert A1 - Rohrlack, Thomas A1 - Rojas-Jimenez, Keilor A1 - Schmeller, Dirk S. A1 - Scholz, Bettina A1 - Seto, Kensuke A1 - Sime-Ngando, Telesphore A1 - Sukenik, Assaf A1 - Van de Waal, Dedmer B. A1 - Van den Wyngaert, Silke A1 - Van Donk, Ellen A1 - Wolinska, Justyna A1 - Wurzbacher, Christian A1 - Agha, Ramsy T1 - Integrating chytrid fungal parasites into plankton ecology: research gaps and needs JF - Environmental microbiology N2 - Chytridiomycota, often referred to as chytrids, can be virulent parasites with the potential to inflict mass mortalities on hosts, causing e.g. changes in phytoplankton size distributions and succession, and the delay or suppression of bloom events. Molecular environmental surveys have revealed an unexpectedly large diversity of chytrids across a wide range of aquatic ecosystems worldwide. As a result, scientific interest towards fungal parasites of phytoplankton has been gaining momentum in the past few years. Yet, we still know little about the ecology of chytrids, their life cycles, phylogeny, host specificity and range. Information on the contribution of chytrids to trophic interactions, as well as co-evolutionary feedbacks of fungal parasitism on host populations is also limited. This paper synthesizes ideas stressing the multifaceted biological relevance of phytoplankton chytridiomycosis, resulting from discussions among an international team of chytrid researchers. It presents our view on the most pressing research needs for promoting the integration of chytrid fungi into aquatic ecology. Y1 - 2017 U6 - https://doi.org/10.1111/1462-2920.13827 SN - 1462-2912 SN - 1462-2920 VL - 19 SP - 3802 EP - 3822 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Rojas-Jimenez, Keilor A1 - Wurzbacher, Christian A1 - Bourne, Elizabeth Charlotte A1 - Chiuchiolo, Amy A1 - Priscu, John C. A1 - Grossart, Hans-Peter T1 - Early diverging lineages within Cryptomycota and Chytridiomycota dominate the fungal communities in ice-covered lakes of the McMurdo Dry Valleys, Antarctica JF - Scientific reports N2 - Antarctic ice-covered lakes are exceptional sites for studying the ecology of aquatic fungi under conditions of minimal human disturbance. In this study, we explored the diversity and community composition of fungi in five permanently covered lake basins located in the Taylor and Miers Valleys of Antarctica. Based on analysis of the 18S rRNA sequences, we showed that fungal taxa represented between 0.93% and 60.32% of the eukaryotic sequences. Cryptomycota and Chytridiomycota dominated the fungal communities in all lakes; however, members of Ascomycota, Basidiomycota, Zygomycota, and Blastocladiomycota were also present. Of the 1313 fungal OTUs identified, the two most abundant, belonging to LKM11 and Chytridiaceae, comprised 74% of the sequences. Significant differences in the community structure were determined among lakes, water depths, habitat features (i.e., brackish vs. freshwaters), and nucleic acids (DNA vs. RNA), suggesting niche differentiation. Network analysis suggested the existence of strong relationships among specific fungal phylotypes as well as between fungi and other eukaryotes. This study sheds light on the biology and ecology of basal fungi in aquatic systems. To our knowledge, this is the first report showing the predominance of early diverging lineages of fungi in pristine limnetic ecosystems, particularly of the enigmatic phylum Cryptomycota. Y1 - 2017 U6 - https://doi.org/10.1038/s41598-017-15598-w SN - 2045-2322 VL - 7 PB - Nature Publ. Group CY - London ER - TY - GEN A1 - Kalinkat, Gregor A1 - Cabral, Juliano Sarmento A1 - Darwall, William A1 - Ficetola, G. Francesco A1 - Fisher, Judith L. A1 - Giling, Darren P. A1 - Gosselin, Marie-Pierre A1 - Grossart, Hans-Peter A1 - Jaehnig, Sonja C. A1 - Jeschke, Jonathan M. A1 - Knopf, Klaus A1 - Larsen, Stefano A1 - Onandia, Gabriela A1 - Paetzig, Marlene A1 - Saul, Wolf-Christian A1 - Singer, Gabriel A1 - Sperfeld, Erik A1 - Jaric, Ivan T1 - Flagship umbrella species needed for the conservation of overlooked aquatic biodiversity T2 - Conservation biology : the journal of the Society for Conservation Biology Y1 - 2017 U6 - https://doi.org/10.1111/cobi.12813 SN - 0888-8892 SN - 1523-1739 VL - 31 SP - 481 EP - 485 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Pedoja, K. A1 - Jara Muñoz, Julius A1 - De Gelder, G. A1 - Robertson, J. A1 - Meschis, M. A1 - Fernandez-Blanco, D. A1 - Nexer, M. A1 - Poprawski, Y. A1 - Dugue, O. A1 - Delcaillau, B. A1 - Bessin, P. A1 - Benabdelouahed, M. A1 - Authemayou, C. A1 - Husson, L. A1 - Regard, V. A1 - Menier, D. A1 - Pinel, B. T1 - Neogene-Quaternary slow coastal uplift of Western Europe through the perspective of sequences of strandlines from the Cotentin Peninsula (Normandy, France) JF - Geomorphology : an international journal on pure and applied geomorphology N2 - The Cotentin Peninsula (Normandy, France) displays sequences of marine terraces and rasas, the latter being wide Late Cenozoic coastal erosion surfaces, that are typical of Western European coasts in Portugal, Spain, France and southern England. Remote sensing imagery and field mapping enabled reappraisal of the Cotentin coastal sequences. From bottom to top, the N Cotentin sequence includes four previously recognized Pleistocene marine terraces (T1 to T4) at elevations <40 m as well as four higher and older rasas (R1 to R4) reaching 200 +/- 5 m in elevation. Low-standing marine terraces are not observed in the central part of the Peninsula and a limited number of terraces are described to the south. The high-standing rasas are widespread all over the peninsula. Such strandline distributions reveal major changes during the Late Cenozoic. Progressive uplift of an irregular sea-floor led to subaerial exposure of bathymetric highs that were carved into rocky platforms, rasas and marine terraces. Eventually, five main islands coalesced and connected to the mainland to the south to form the Cotentin Peninsula. On the basis of previous dating of the last interglacial maximum terrace (i.e. Marine Isotopic Stage, MIS 5e), sequential morphostratigraphy and modelling, we have reappraised uplift rates and derived: (i) mean Upper Pleistocene (i.e. since MIS 5e similar to 122 +/- 6 ka, i.e. kilo annum) apparent uplift rates of 0.04 +/- 0.01 mm/yr, (ii) mean Middle Pleistocene eustasy-corrected uplift rates of 0.09 +/- 0.03 mm/yr, and (iii) low mean Pleistocene uplift rates of 0.01 mm/yr. Extrapolations of these slow rates combined with geological evidence implies that the formation of the sequences from the Cotentin Peninsula occurred between 3 Ma (Pliocene) and 15 Ma (Miocene), which cannot be narrowed down further without additional research. Along the coasts of Western Europe, sequences of marine terraces and rasas are widespread (169 preserve the MIS Se benchmark). In Spain, Portugal, S England and other parts of western France, the sequences morphostratigraphy is very similar to that of Cotentin. The onset of such Western European sequences occurred during the Miocene (e.g. Spain) or Pliocene (e.g. Portugal). We interpret this Neogene-Quaternary coastal uplift as a symptom of the increasing lithospheric compression that accompanies Cenozoic orogenies. (C) 2017 Elsevier B.V. All rights reserved. KW - Marine terrace KW - Rasa KW - Cotentin and Western Europe KW - Neogene and Quaternary coastal uplift Y1 - 2017 U6 - https://doi.org/10.1016/j.geomorph.2017.11.021 SN - 0169-555X SN - 1872-695X VL - 303 SP - 338 EP - 356 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Sadovnichii, V. A. A1 - Panasyuk, M. I. A1 - Amelyushkin, A. M. A1 - Bogomolov, V. V. A1 - Benghin, V. V. A1 - Garipov, G. K. A1 - Kalegaev, V. V. A1 - Klimov, P. A. A1 - Khrenov, B. A. A1 - Petrov, V. L. A1 - Sharakin, S. A. A1 - Shirokov, A. V. A1 - Svertilov, S. I. A1 - Zotov, M. Y. A1 - Yashin, I. V. A1 - Gorbovskoy, E. S. A1 - Lipunov, V. M. A1 - Park, I. H. A1 - Lee, J. A1 - Jeong, S. A1 - Kim, M. B. A1 - Jeong, H. M. A1 - Shprits, Yuri Y. A1 - Angelopoulos, V. A1 - Russell, C. T. A1 - Runov, A. A1 - Turner, D. A1 - Strangeway, R. J. A1 - Caron, R. A1 - Biktemerova, S. A1 - Grinyuk, A. A1 - Lavrova, M. A1 - Tkachev, L. A1 - Tkachenko, A. A1 - Martinez, O. A1 - Salazar, H. A1 - Ponce, E. T1 - "Lomonosov" Satellite-Space Observatory to Study Extreme Phenomena in Space JF - Space science reviews N2 - The "Lomonosov" space project is lead by Lomonosov Moscow State University in collaboration with the following key partners: Joint Institute for Nuclear Research, Russia, University of California, Los Angeles (USA), University of Pueblo (Mexico), Sungkyunkwan University (Republic of Korea) and with Russian space industry organi-zations to study some of extreme phenomena in space related to astrophysics, astroparticle physics, space physics, and space biology. The primary goals of this experiment are to study: -Ultra-high energy cosmic rays (UHECR) in the energy range of the Greizen-ZatsepinKuzmin (GZK) cutoff; -Ultraviolet (UV) transient luminous events in the upper atmosphere; -Multi-wavelength study of gamma-ray bursts in visible, UV, gamma, and X-rays; -Energetic trapped and precipitated radiation (electrons and protons) at low-Earth orbit (LEO) in connection with global geomagnetic disturbances; -Multicomponent radiation doses along the orbit of spacecraft under different geomagnetic conditions and testing of space segments of optical observations of space-debris and other space objects; -Instrumental vestibular-sensor conflict of zero-gravity phenomena during space flight. This paper is directed towards the general description of both scientific goals of the project and scientific equipment on board the satellite. The following papers of this issue are devoted to detailed descriptions of scientific instruments. KW - Gamma-ray bursts KW - Ultra-high energy cosmic rays KW - Radiation belts KW - Space mission Y1 - 2017 U6 - https://doi.org/10.1007/s11214-017-0425-x SN - 0038-6308 SN - 1572-9672 VL - 212 SP - 1705 EP - 1738 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Giling, Darren P. A1 - Nejstgaard, Jens C. A1 - Berger, Stella A. A1 - Grossart, Hans-Peter A1 - Kirillin, Georgiy A1 - Penske, Armin A1 - Lentz, Maren A1 - Casper, Peter A1 - Sareyka, Joerg A1 - Gessner, Mark O. T1 - Thermocline deepening boosts ecosystem metabolism: evidence from a large-scale lake enclosure experiment simulating a summer storm JF - Global change biology N2 - Extreme weather events can pervasively influence ecosystems. Observations in lakes indicate that severe storms in particular can have pronounced ecosystem-scale consequences, but the underlying mechanisms have not been rigorously assessed in experiments. One major effect of storms on lakes is the redistribution of mineral resources and plankton communities as a result of abrupt thermocline deepening. We aimed at elucidating the importance of this effect by mimicking in replicated large enclosures (each 9 m in diameter, ca. 20 m deep, ca. 1300 m 3 in volume) a mixing event caused by a severe natural storm that was previously observed in a deep clear-water lake. Metabolic rates were derived from diel changes in vertical profiles of dissolved oxygen concentrations using a Bayesian modelling approach, based on high-frequency measurements. Experimental thermocline deepening stimulated daily gross primary production (GPP) in surface waters by an average of 63% for > 4 weeks even though thermal stratification re-established within 5 days. Ecosystem respiration (ER) was tightly coupled to GPP, exceeding that in control enclosures by 53% over the same period. As GPP responded more strongly than ER, net ecosystem productivity (NEP) of the entire water column was also increased. These protracted increases in ecosystem metabolism and autotrophy were driven by a proliferation of inedible filamentous cyanobacteria released from light and nutrient limitation after they were entrained from below the thermocline into the surface water. Thus, thermocline deepening by a single severe storm can induce prolonged responses of lake ecosystem metabolism independent of other storm-induced effects, such as inputs of terrestrial materials by increased catchment run-off. This highlights that future shifts in frequency, severity or timing of storms are an important component of climate change, whose impacts on lake thermal structure will superimpose upon climate trends to influence algal dynamics and organic matter cycling in clear-water lakes. Keywords: climate variability, ecosystem productivity, extreme events, gross primary production, mesocosm, respiration stratified lakes KW - climate variability KW - ecosystem productivity KW - extreme events KW - gross primary production KW - mesocosm KW - respiration stratified lakes Y1 - 2017 U6 - https://doi.org/10.1111/gcb.13512 SN - 1354-1013 SN - 1365-2486 VL - 23 SP - 1448 EP - 1462 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Nidever, David L. A1 - Olsen, Knut A1 - Walker, Alistair R. A1 - Katherina Vivas, A. A1 - Blum, Robert D. A1 - Kaleida, Catherine A1 - Choi, Yumi A1 - Conn, Blair C. A1 - Gruendl, Robert A. A1 - Bell, Eric F. A1 - Besla, Gurtina A1 - Munoz, Ricardo R. A1 - Gallart, Carme A1 - Martin, Nicolas F. A1 - Olszewski, Edward W. A1 - Saha, Abhijit A1 - Monachesi, Antonela A1 - Monelli, Matteo A1 - de Boer, Thomas J. L. A1 - Johnson, L. Clifton A1 - Zaritsky, Dennis A1 - Stringfellow, Guy S. A1 - van der Marel, Roeland P. A1 - Cioni, Maria-Rosa L. A1 - Jin, Shoko A1 - Majewski, Steven R. A1 - Martinez-Delgado, David A1 - Monteagudo, Lara A1 - Noel, Noelia E. D. A1 - Bernard, Edouard J. A1 - Kunder, Andrea A1 - Chu, You-Hua A1 - Bell, Cameron P. M. A1 - Santana, Felipe A1 - Frechem, Joshua A1 - Medina, Gustavo E. A1 - Parkash, Vaishali A1 - Seron Navarrete, J. C. A1 - Hayes, Christian T1 - SMASH: Survey of the MAgellanic Stellar History JF - The astronomical journal N2 - The Large and Small Magellanic Clouds are unique local laboratories for studying the formation and evolution of small galaxies in exquisite detail. The Survey of the MAgellanic Stellar History (SMASH) is an NOAO community Dark Energy Camera (DECam) survey of the Clouds mapping 480 deg2 (distributed over similar to 2400 square degrees at similar to 20% filling factor) to similar to 24th. mag in ugriz. The primary goals of SMASH are to identify low surface brightness stellar populations associated with the stellar halos and tidal debris of the Clouds, and to derive spatially resolved star formation histories. Here, we present a summary of the survey, its data reduction, and a description of the first public Data Release (DR1). The SMASH DECam data have been reduced with a combination of the NOAO Community Pipeline, the PHOTRED automated point-spread-function photometry pipeline, and custom calibration software. The astrometric precision is similar to 15 mas and the accuracy is similar to 2 mas with respect to the Gaia reference frame. The photometric precision is similar to 0.5%-0.7% in griz and similar to 1% in u with a calibration accuracy of similar to 1.3% in all bands. The median 5s point source depths in ugriz are 23.9, 24.8, 24.5, 24.2, and 23.5 mag. The SMASH data have already been used to discover the Hydra II Milky Way satellite, the SMASH 1 old globular cluster likely associated with the LMC, and extended stellar populations around the LMC out to R. similar to. 18.4 kpc. SMASH DR1 contains measurements of similar to 100 million objects distributed in 61 fields. A prototype version of the NOAO Data Lab provides data access and exploration tools. KW - galaxies: dwarf KW - galaxies: individual (Large Magellanic Cloud, Small Magellanic Cloud) KW - Local Group KW - Magellanic Clouds KW - surveys Y1 - 2017 U6 - https://doi.org/10.3847/1538-3881/aa8d1c SN - 0004-6256 SN - 1538-3881 VL - 154 SP - 310 EP - 326 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Collado-Fregoso, Elisa A1 - Hood, Samantha N. A1 - Shoaee, Safa A1 - Schröder, Bob C. A1 - McCulloch, Iain A1 - Kassal, Ivan A1 - Neher, Dieter A1 - Durrant, James R. T1 - Intercalated vs Nonintercalated Morphologies in Donor-Acceptor Bulk Heterojunction Solar Cells: PBTTT:Fullerene Charge Generation and Recombination Revisited JF - The journal of physical chemistry letters N2 - In this Letter, we study the role of the donor:acceptor interface nanostructure upon charge separation and recombination in organic photovoltaic devices and blend films, using mixtures of PBTTT and two different fullerene derivatives (PC70BM and ICTA) as models for intercalated and nonintercalated morphologies, respectively. Thermodynamic simulations show that while the completely intercalated system exhibits a large free-energy barrier for charge separation, this barrier is significantly lower in the nonintercalated system and almost vanishes when energetic disorder is included in the model. Despite these differences, both femtosecond-resolved transient absorption spectroscopy (TAS) and time-delayed collection field (TDCF) exhibit extensive first-order losses in both systems, suggesting that geminate pairs are the primary product of photoexcitation. In contrast, the system that comprises a combination of fully intercalated polymer:fullerene areas and fullerene-aggregated domains (1:4 PBTTT:PC70BM) is the only one that shows slow, second-order recombination of free charges, resulting in devices with an overall higher short-circuit current and fill factor. This study therefore provides a novel consideration of the role of the interfacial nanostructure and the nature of bound charges and their impact upon charge generation and recombination. Y1 - 2017 U6 - https://doi.org/10.1021/acs.jpclett.7b01571 SN - 1948-7185 VL - 8 SP - 4061 EP - 4068 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Nikolis, Vasileios C. A1 - Benduhn, Johannes A1 - Holzmueller, Felix A1 - Piersimoni, Fortunato A1 - Lau, Matthias A1 - Zeika, Olaf A1 - Neher, Dieter A1 - Koerner, Christian A1 - Spoltore, Donato A1 - Vandewal, Koen T1 - Reducing Voltage Losses in Cascade Organic Solar Cells while Maintaining High External Quantum Efficiencies JF - dvanced energy materials N2 - High photon energy losses limit the open-circuit voltage (V-OC) and power conversion efficiency of organic solar cells (OSCs). In this work, an optimization route is presented which increases the V-OC by reducing the interfacial area between donor (D) and acceptor (A). This optimization route concerns a cascade device architecture in which the introduction of discontinuous interlayers between alpha-sexithiophene (alpha-6T) (D) and chloroboron subnaphthalocyanine (SubNc) (A) increases the V-OC of an alpha-6T/SubNc/SubPc fullerene-free cascade OSC from 0.98 V to 1.16 V. This increase of 0.18 V is attributed solely to the suppression of nonradiative recombination at the D-A interface. By accurately measuring the optical gap (E-opt) and the energy of the charge-transfer state (E-CT) of the studied OSC, a detailed analysis of the overall voltage losses is performed. E-opt - qV(OC) losses of 0.58 eV, which are among the lowest observed for OSCs, are obtained. Most importantly, for the V-OC-optimized devices, the low-energy (700 nm) external quantum efficiency (EQE) peak remains high at 79%, despite a minimal driving force for charge separation of less than 10 meV. This work shows that low-voltage losses can be combined with a high EQE in organic photovoltaic devices. KW - energy losses KW - nonradiative recombination KW - open-circuit voltage KW - organic solar cells KW - voltage losses Y1 - 2017 U6 - https://doi.org/10.1002/aenm.201700855 SN - 1614-6832 SN - 1614-6840 VL - 7 SP - 122 EP - 136 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Drozdov, Alexander A1 - Shprits, Yuri Y. A1 - Usanova, Maria E. A1 - Aseev, Nikita A1 - Kellerman, Adam C. A1 - Zhu, H. T1 - EMIC wave parameterization in the long-term VERB code simulation JF - Journal of geophysical research : Space physics N2 - Electromagnetic ion cyclotron (EMIC) waves play an important role in the dynamics of ultrarelativistic electron population in the radiation belts. However, as EMIC waves are very sporadic, developing a parameterization of such wave properties is a challenging task. Currently, there are no dynamic, activity-dependent models of EMIC waves that can be used in the long-term (several months) simulations, which makes the quantitative modeling of the radiation belt dynamics incomplete. In this study, we investigate Kp, Dst, and AE indices, solar wind speed, and dynamic pressure as possible parameters of EMIC wave presence. The EMIC waves are included in the long-term simulations (1year, including different geomagnetic activity) performed with the Versatile Electron Radiation Belt code, and we compare results of the simulation with the Van Allen Probes observations. The comparison shows that modeling with EMIC waves, parameterized by solar wind dynamic pressure, provides a better agreement with the observations among considered parameterizations. The simulation with EMIC waves improves the dynamics of ultrarelativistic fluxes and reproduces the formation of the local minimum in the phase space density profiles. KW - radiation belts KW - VERB code KW - EMIC Y1 - 2017 U6 - https://doi.org/10.1002/2017JA024389 SN - 2169-9380 SN - 2169-9402 VL - 122 SP - 8488 EP - 8501 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Aseev, Nikita A1 - Shprits, Yuri Y. A1 - Drozdov, Alexander A1 - Kellerman, Adam C. A1 - Usanova, Maria E. A1 - Wang, D. A1 - Zhelavskaya, Irina T1 - Signatures of Ultrarelativistic Electron Loss in the Heart of the Outer Radiation Belt Measured by Van Allen Probes JF - Journal of geophysical research : Space physics N2 - Up until recently, signatures of the ultrarelativistic electron loss driven by electromagnetic ion cyclotron (EMIC) waves in the Earth's outer radiation belt have been limited to direct or indirect measurements of electron precipitation or the narrowing of normalized pitch angle distributions in the heart of the belt. In this study, we demonstrate additional observational evidence of ultrarelativistic electron loss that can be driven by resonant interaction with EMIC waves. We analyzed the profiles derived from Van Allen Probe particle data as a function of time and three adiabatic invariants between 9 October and 29 November 2012. New local minimums in the profiles are accompanied by the narrowing of normalized pitch angle distributions and ground‐based detection of EMIC waves. Such a correlation may be indicative of ultrarelativistic electron precipitation into the Earth's atmosphere caused by resonance with EMIC waves. Y1 - 2017 U6 - https://doi.org/10.1002/2017JA024485 SN - 2169-9380 SN - 2169-9402 VL - 122 SP - 10102 EP - 10111 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Shprits, Yuri Y. A1 - Angelopoulos, V. A1 - Russell, C. T. A1 - Strangeway, R. J. A1 - Runov, A. A1 - Turner, D. A1 - Caron, R. A1 - Cruce, P. A1 - Leneman, D. A1 - Michaelis, I. A1 - Petrov, V. A1 - Panasyuk, M. A1 - Yashin, I. A1 - Drozdov, Alexander A1 - Russell, C. L. A1 - Kalegaev, V. A1 - Nazarkov, I. A1 - Clemmons, J. H. T1 - Scientific Objectives of Electron Losses and Fields INvestigation Onboard Lomonosov Satellite JF - Space science reviews N2 - The objective of the Electron Losses and Fields INvestigation on board the Lomonosov satellite ( ELFIN-L) project is to determine the energy spectrum of precipitating energetic electrons and ions and, together with other polar-orbiting and equatorial missions, to better understand the mechanisms responsible for scattering these particles into the atmosphere. This mission will provide detailed measurements of the radiation environment at low altitudes. The 400-500 km sun-synchronous orbit of Lomonosov is ideal for observing electrons and ions precipitating into the atmosphere. This mission provides a unique opportunity to test the instruments. Similar suite of instruments will be flown in the future NSF-and NASA-supported spinning CubeSat ELFIN satellites which will augment current measurements by providing detailed information on pitch-angle distributions of precipitating and trapped particles. KW - Magnetospheric physics KW - Observations KW - Particles precipitating KW - Particles trapped KW - Radiation belts Y1 - 2017 U6 - https://doi.org/10.1007/s11214-017-0455-4 SN - 0038-6308 SN - 1572-9672 VL - 214 IS - 1 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Shprits, Yuri Y. A1 - Kellerman, Adam C . A1 - Aseev, Nikita A1 - Drozdov, Alexander A1 - Michaelis, Ingo T1 - Multi-MeV electron loss in the heart of the radiation belts JF - Geophysical research letters N2 - Significant progress has been made in recent years in understanding acceleration mechanisms in the Earth's radiation belts. In particular, a number of studies demonstrated the importance of the local acceleration by analyzing the radial profiles of phase space density (PSD) and observing building up peaks in PSD. In this study, we focus on understanding of the local loss using very similar tools. The profiles of PSD for various values of the first adiabatic invariants during the previously studied 17 January 2013 storm are presented and discussed. The profiles of PSD show clear deepening minimums consistent with the scattering by electromagnetic ion cyclotron waves. Long-term evolution shows that local minimums in PSD can persist for relatively long times. During considered interval of time the deepening minimums were observed around L* = 4 during 17 January 2013 storm and around L* = 3.5 during 1 March 2013 storm. This study shows a new method that can help identify the location, magnitude, and time of the local loss and will help quantify local loss in the future. This study also provides additional clear and definitive evidence that local loss plays a major role for the dynamics of the multi-MeV electrons. Y1 - 2017 U6 - https://doi.org/10.1002/2016GL072258 SN - 0094-8276 SN - 1944-8007 VL - 44 IS - 3 SP - 1204 EP - 1209 PB - American Geophysical Union CY - Washington ER - TY - JOUR A1 - Kwamen, C. A1 - Rössle, Matthias A1 - Reinhardt, M. A1 - Leitenberger, Wolfram A1 - Zamponi, Flavio A1 - Alexe, Marin A1 - Bargheer, Matias T1 - Simultaneous dynamic characterization of charge and structural motion during ferroelectric switching JF - Physical review : B, Condensed matter and materials physics N2 - Monitoring structural changes in ferroelectric thin films during electric field induced polarization switching is important for a full microscopic understanding of the coupled motion of charges, atoms, and domainwalls in ferroelectric nanostructures. We combine standard ferroelectric test sequences of switching and nonswitching electrical pulses with time-resolved x-ray diffraction to investigate the structural response of a nanoscale Pb(Zr0.2Ti0.8)O-3 ferroelectric oxide capacitor upon charging, discharging, and polarization reversal. We observe that a nonlinear piezoelectric response of the ferroelectric layer develops on a much longer time scale than the RC time constant of the device. The complex atomic motion during the ferroelectric polarization reversal starts with a contraction of the lattice, whereas the expansive piezoelectric response sets in after considerable charge flow due to the applied voltage pulses on the electrodes of the capacitor. Our simultaneous measurements on a working device elucidate and visualize the complex interplay of charge flow and structural motion and challenges theoretical modeling. Y1 - 2017 U6 - https://doi.org/10.1103/PhysRevB.96.134105 SN - 2469-9950 SN - 2469-9969 VL - 96 PB - American Physical Society CY - College Park ER - TY - JOUR A1 - Martinez-Valdes, Eduardo Andrés A1 - Negro, F. A1 - Laine, C. M. A1 - Falla, D. A1 - Mayer, Frank A1 - Farina, Dario T1 - Tracking motor units longitudinally across experimental sessions with high-density surface electromyography JF - The Journal of Physiology N2 - A new method is proposed for tracking individual motor units (MUs) across multiple experimental sessions on different days. The technique is based on a novel decomposition approach for high-density surface electromyography and was tested with two experimental studies for reliability and sensitivity. Experiment I (reliability): ten participants performed isometric knee extensions at 10, 30, 50 and 70% of their maximum voluntary contraction (MVC) force in three sessions, each separated by 1 week. Experiment II (sensitivity): seven participants performed 2 weeks of endurance training (cycling) and were tested pre-post intervention during isometric knee extensions at 10 and 30% MVC. The reliability (Experiment I) and sensitivity (Experiment II) of the measured MU properties were compared for the MUs tracked across sessions, with respect to all MUs identified in each session. In Experiment I, on average 38.3% and 40.1% of the identified MUs could be tracked across two sessions (1 and 2 weeks apart), for the vastus medialis and vastus lateralis, respectively. Moreover, the properties of the tracked MUs were more reliable across sessions than those of the full set of identified MUs (intra-class correlation coefficients ranged between 0.63-0.99 and 0.39-0.95, respectively). In Experiment II, similar to 40% of the MUs could be tracked before and after the training intervention and training-induced changes in MU conduction velocity had an effect size of 2.1 (tracked MUs) and 1.5 (group of all identified motor units). These results show the possibility of monitoring MU properties longitudinally to document the effect of interventions or the progression of neuromuscular disorders. Y1 - 2016 U6 - https://doi.org/10.1113/JP273662 SN - 0022-3751 SN - 1469-7793 VL - 595 SP - 1479 EP - 1496 PB - Wiley CY - Hoboken ER - TY - GEN A1 - Hirschmueller, Anja A1 - Baur, Heiner A1 - Braun, Sepp A1 - Kreuz, Peter C. A1 - Suedkamp, Norbert P A1 - Niemeyer, Philipp T1 - Rehabilitation after autologous chondrocyte implantation for isolated cartilage defects of the knee N2 - Autologous chondrocyte implantation for treatment of isolated cartilage defects of the knee has become well established. Although various publications report technical modifications, clinical results, and cell-related issues, little is known about appropriate and optimal rehabilitation after autologous chondrocyte implantation. This article reviews the literature on rehabilitation after autologous chondrocyte implantation and presents a rehabilitation protocol that has been developed considering the best available evidence and has been successfully used for several years in a large number of patients who underwent autologous chondrocyte implantation for cartilage defects of the knee. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 367 KW - autologous chondrocyte implantation KW - cartilage repair KW - cartilage defect KW - cell transplantation KW - knee joint KW - rehabilitation Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-403170 ER - TY - JOUR A1 - Abdalla, Hassan E. A1 - Abramowski, Attila A1 - Aharonian, Felix A. A1 - Benkhali, Faical Ait A1 - Akhperjanian, A. G. A1 - Andersson, T. A1 - Anguner, Ekrem Oǧuzhan A1 - Arakawa, M. A1 - Arrieta, M. A1 - Aubert, Pierre A1 - Backes, Michael A1 - Balzer, Arnim A1 - Barnard, Michelle A1 - Becherini, Yvonne A1 - Tjus, J. Becker A1 - Berge, David A1 - Bernhard, Sabrina A1 - Bernlöhr, K. A1 - Blackwell, R. A1 - Böttcher, Markus A1 - Boisson, Catherine A1 - Bolmont, J. A1 - Bonnefoy, S. A1 - Bordas, Pol A1 - Bregeon, Johan A1 - Brun, Francois A1 - Brun, Pierre A1 - Bryan, Mark A1 - Buechele, M. A1 - Bulik, Tomasz A1 - Capasso, M. A1 - Carr, John A1 - Casanova, Sabrina A1 - Cerruti, M. A1 - Chakraborty, N. A1 - Chaves, Ryan C. G. A1 - Chen, Andrew A1 - Chevalier, J. A1 - Coffaro, M. A1 - Colafrancesco, Sergio A1 - Cologna, Gabriele A1 - Condon, B. A1 - Conrad, Jan A1 - Cui, Y. A1 - Davids, I. D. A1 - Decock, J. A1 - Degrange, B. A1 - Deil, C. A1 - Devin, J. A1 - de Wilt, P. A1 - Dirson, L. A1 - Djannati-Atai, A. A1 - Domainko, W. A1 - Donath, A. A1 - Dutson, K. A1 - Dyks, J. A1 - Edwards, T. A1 - Egberts, Kathrin A1 - Eger, P. A1 - Ernenwein, J. -P. A1 - Eschbach, S. A1 - Farnier, C. A1 - Fegan, S. A1 - Fernandes, M. V. A1 - Fiasson, A. A1 - Fontaine, G. A1 - Foerster, A. A1 - Funk, S. A1 - Fuessling, M. A1 - Gabici, S. A1 - Gallant, Y. A. A1 - Garrigoux, T. A1 - Giavitto, G. A1 - Giebels, B. A1 - Glicenstein, J. F. A1 - Gottschall, D. A1 - Goyal, A. A1 - Grondin, M. -H. A1 - Hahn, J. A1 - Haupt, M. A1 - Hawkes, J. A1 - Heinzelmann, G. A1 - Henri, G. A1 - Hermann, G. A1 - Hinton, James Anthony A1 - Hofmann, W. A1 - Hoischen, Clemens A1 - Holch, Tim Lukas A1 - Holler, M. A1 - Horns, D. A1 - Ivascenko, A. A1 - Iwasaki, H. A1 - Jacholkowska, A. A1 - Jamrozy, M. A1 - Janiak, M. A1 - Jankowsky, D. A1 - Jankowsky, F. A1 - Jingo, M. A1 - Jogler, T. A1 - Jouvin, L. A1 - Jung-Richardt, I. A1 - Kastendieck, M. A. A1 - Katarzynski, K. A1 - Katsuragawa, M. A1 - Katz, U. A1 - Kerszberg, D. A1 - Khangulyan, D. A1 - Khelifi, B. A1 - King, J. A1 - Klepser, S. A1 - Klochkov, D. A1 - Kluzniak, W. A1 - Kolitzus, D. A1 - Komin, Nu. A1 - Kosack, K. A1 - Krakau, S. A1 - Kraus, M. A1 - Kruger, P. P. A1 - Laffon, H. A1 - Lamanna, G. A1 - Lau, J. A1 - Lees, J. -P. A1 - Lefaucheur, J. A1 - Lefranc, V. A1 - Lemiere, A. A1 - Lemoine-Goumard, M. A1 - Lenain, J. -P. A1 - Leser, Eva A1 - Lohse, T. A1 - Lorentz, M. A1 - Liu, R. A1 - Lopez-Coto, R. A1 - Lypova, I. A1 - Marandon, V. A1 - Marcowith, Alexandre A1 - Mariaud, C. A1 - Marx, R. A1 - Maurin, G. A1 - Maxted, N. A1 - Mayer, M. A1 - Meintjes, P. J. A1 - Meyer, M. A1 - Mitchell, A. M. W. A1 - Moderski, R. A1 - Mohamed, M. A1 - Mohrmann, L. A1 - Mora, K. A1 - Moulin, Emmanuel A1 - Murach, T. A1 - Nakashima, S. A1 - de Naurois, M. A1 - Niederwanger, F. A1 - Niemiec, J. A1 - Oakes, L. A1 - Odaka, H. A1 - Ohm, S. A1 - Ostrowski, M. A1 - Oya, I. A1 - Padovani, M. A1 - Panter, M. A1 - Parsons, R. D. A1 - Pekeur, N. W. A1 - Pelletier, G. A1 - Perennes, C. A1 - Petrucci, P. -O. A1 - Peyaud, B. A1 - Piel, Q. A1 - Pita, S. A1 - Poon, H. A1 - Prokhorov, D. A1 - Prokoph, H. A1 - Puehlhofer, G. A1 - Punch, M. A1 - Quirrenbach, A. A1 - Raab, S. A1 - Rauth, R. A1 - Reimer, A. A1 - Reimer, O. A1 - Renaud, M. A1 - de los Reyes, R. A1 - Richter, S. A1 - Rieger, F. A1 - Romoli, C. A1 - Rowell, G. A1 - Rudak, B. A1 - Rulten, C. B. A1 - Sahakian, V. A1 - Saito, S. A1 - Salek, D. A1 - Sanchez, David M. A1 - Santangelo, Andrea A1 - Sasaki, M. A1 - Schlickeiser, R. A1 - Schussler, F. A1 - Schulz, A. A1 - Schwanke, U. A1 - Schwemmer, S. A1 - Seglar-Arroyo, M. A1 - Settimo, M. A1 - Seyffert, A. S. A1 - Shafi, N. A1 - Shilon, I. A1 - Simoni, R. A1 - Sol, H. A1 - Spanier, F. A1 - Spengler, G. A1 - Spies, F. A1 - Stawarz, L. A1 - Steenkamp, R. A1 - Stegmann, Christian A1 - Stycz, K. A1 - Sushch, Iurii A1 - Takahashi, T. A1 - Tavernet, J. -P. A1 - Tavernier, T. A1 - Taylor, A. M. A1 - Terrier, R. A1 - Tibaldo, L. A1 - Tiziani, D. A1 - Tluczykont, M. A1 - Trichard, C. A1 - Tsuji, N. A1 - Tuffs, R. A1 - Uchiyama, Y. A1 - van der Walt, D. J. A1 - van Eldik, C. A1 - van Rensburg, C. A1 - van Soelen, B. A1 - Vasileiadis, G. A1 - Veh, J. A1 - Venter, C. A1 - Viana, A. A1 - Vincent, P. A1 - Vink, J. A1 - Voisin, F. A1 - Voelk, H. J. A1 - Vuillaume, T. A1 - Wadiasingh, Z. A1 - Wagner, S. J. A1 - Wagner, P. A1 - Wagner, R. M. A1 - White, R. A1 - Wierzcholska, A. A1 - Willmann, P. A1 - Woernlein, A. A1 - Wouters, D. A1 - Yang, R. A1 - Zaborov, D. A1 - Zacharias, M. A1 - Zanin, R. A1 - Zdziarski, A. A. A1 - Zech, Alraune A1 - Zefi, F. A1 - Ziegler, A. A1 - Zywucka, N. T1 - Measurement of the EBL spectral energy distribution using the VHE gamma-ray spectra of HESS blazars JF - Astronomy and astrophysics : an international weekly journal N2 - Very high-energy gamma rays (VHE, E greater than or similar to 100 GeV) propagating over cosmological distances can interact with the low-energy photons of the extragalactic background light (EBL) and produce electron-positron pairs. The transparency of the Universe to VHE gamma rays is then directly related to the spectral energy distribution (SED) of the EBL. The observation of features in the VHE energy spectra of extragalactic sources allows the EBL to be measured, which otherwise is very difficult. An EBL model-independent measurement of the EBL SED with the H.E.S.S. array of Cherenkov telescopes is presented. It was obtained by extracting the EBL absorption signal from the reanalysis of high-quality spectra of blazars. From H.E.S.S. data alone the EBL signature is detected at a significance of 9.5 sigma, and the intensity of the EBL obtained in different spectral bands is presented together with the associated gamma-ray horizon. KW - gamma rays: galaxies KW - BL Lacertae objects: general KW - cosmic background radiation KW - infrared: diffuse background Y1 - 2017 U6 - https://doi.org/10.1051/0004-6361/201731200 SN - 1432-0746 VL - 606 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Abdalla, Hassan E. A1 - Abramowski, Attila A1 - Aharonian, Felix A. A1 - Benkhali, Faical Ait A1 - Anguner, Ekrem Oǧuzhan A1 - Arakawa, M. A1 - Arrieta, M. A1 - Aubert, Pierre A1 - Backes, Michael A1 - Balzer, Arnim A1 - Barnard, Michelle A1 - Becherini, Yvonne A1 - Tjus, J. Becker A1 - Berge, David A1 - Bernhard, Sabrina A1 - Bernlöhr, K. A1 - Blackwell, R. A1 - Böttcher, Markus A1 - Boisson, Catherine A1 - Bolmont, J. A1 - Bonnefoy, S. A1 - Bordas, Pol A1 - Bregeon, Johan A1 - Brun, Francois A1 - Brun, Pierre A1 - Bryan, Mark A1 - Buechele, M. A1 - Bulik, Tomasz A1 - Capasso, M. A1 - Caroff, S. A1 - Carosi, A. A1 - Casanova, Sabrina A1 - Cerruti, M. A1 - Chakraborty, N. A1 - Chaves, Ryan C. G. A1 - Chen, Andrew A1 - Chevalier, J. A1 - Colafrancesco, Sergio A1 - Condon, B. A1 - Conrad, Jan A1 - Davids, I. D. A1 - Decock, J. A1 - Deil, C. A1 - Devin, J. A1 - deWilt, P. A1 - Dirson, L. A1 - Djannati-Atai, A. A1 - Donath, A. A1 - Dutson, K. A1 - Dyks, J. A1 - Edwards, T. A1 - Egberts, Kathrin A1 - Emery, G. A1 - Ernenwein, J. -P. A1 - Eschbach, S. A1 - Farnier, C. A1 - Fegan, S. A1 - Fernandes, M. V. A1 - Fiasson, A. A1 - Fontaine, G. A1 - Funk, S. A1 - Fuessling, M. A1 - Gabici, S. A1 - Gallant, Y. A. A1 - Garrigoux, T. A1 - Gate, F. A1 - Giavitto, G. A1 - Giebels, B. A1 - Glawion, D. A1 - Glicenstein, J. F. A1 - Gottschall, D. A1 - Grondin, M. -H. A1 - Hahn, J. A1 - Haupt, M. A1 - Hawkes, J. A1 - Heinzelmann, G. A1 - Henri, G. A1 - Hermann, G. A1 - Hinton, James Anthony A1 - Hofmann, W. A1 - Hoischen, Clemens A1 - Holch, Tim Lukas A1 - Holler, M. A1 - Horns, D. A1 - Ivascenko, A. A1 - Iwasaki, H. A1 - Jacholkowska, A. A1 - Jamrozy, M. A1 - Jankowsky, D. A1 - Jankowsky, F. A1 - Jingo, M. A1 - Jouvin, L. A1 - Jung-Richardt, I. A1 - Kastendieck, M. A. A1 - Katarzynski, K. A1 - Katsuragawa, M. A1 - Katz, U. A1 - Kerszberg, D. A1 - Khangulyan, D. A1 - Khelifi, B. A1 - King, J. A1 - Klepser, S. A1 - Klochkov, D. A1 - Kluzniak, W. A1 - Komin, Nu. A1 - Kosack, K. A1 - Krakau, S. A1 - Kraus, M. A1 - Kruer, P. P. A1 - Laffon, H. A1 - Lamanna, G. A1 - Lau, J. A1 - Lees, J. -P. A1 - Lefaucheur, J. A1 - Lemiere, A. A1 - Lemoine-Goumard, M. A1 - Lenain, J. -P. A1 - Leser, Eva A1 - Lohse, T. A1 - Lorentz, M. A1 - Liu, R. A1 - Lopez-Coto, R. A1 - Lypova, I. A1 - Malyshev, D. A1 - Marandon, V. A1 - Marcowith, Alexandre A1 - Mariaud, C. A1 - Marx, R. A1 - Maurin, G. A1 - Maxted, N. A1 - Mayer, M. A1 - Meintjes, P. J. A1 - Meyer, M. A1 - Mitchell, A. M. W. A1 - Moderski, R. A1 - Mohamed, M. A1 - Mohrmann, L. A1 - Mora, K. A1 - Moulin, Emmanuel A1 - Murach, T. A1 - Nakashima, S. A1 - de Naurois, M. A1 - Ndiyavala, H. A1 - Niederwanger, F. A1 - Niemiec, J. A1 - Oakes, L. A1 - Odaka, H. A1 - Ohm, S. A1 - Ostrowski, M. A1 - Oya, I. A1 - Padovani, M. A1 - Panter, M. A1 - Parsons, R. D. A1 - Pekeur, N. W. A1 - Pelletier, G. A1 - Perennes, C. A1 - Petrucci, P. -O. A1 - Peyaud, B. A1 - Piel, Q. A1 - Pita, S. A1 - Poireau, V. A1 - Poon, H. A1 - Prokhorov, D. A1 - Prokoph, H. A1 - Puehlhofer, G. A1 - Punch, M. A1 - Quirrenbach, A. A1 - Raab, S. A1 - Rauth, R. A1 - Reimer, A. A1 - Reimer, O. A1 - Renaud, M. A1 - de los Reyes, R. A1 - Rieger, F. A1 - Rinchiuso, L. A1 - Romoli, C. A1 - Rowell, G. A1 - Rudak, B. A1 - Rulten, C. B. A1 - Sahakian, V. A1 - Saito, S. A1 - Sanchez, David M. A1 - Santangelo, Andrea A1 - Sasaki, M. A1 - Schlickeiser, R. A1 - Schussler, F. A1 - Schulz, A. A1 - Schwanke, U. A1 - Schwemmer, S. A1 - Seglar-Arroyo, M. A1 - Settimo, M. A1 - Seyffert, A. S. A1 - Shafi, N. A1 - Shilon, I. A1 - Shiningayamwe, K. A1 - Simoni, R. A1 - Sol, H. A1 - Spanier, F. A1 - Spir-Jacob, M. A1 - Stawarz, L. A1 - Steenkamp, R. A1 - Stegmann, Christian A1 - Steppa, Constantin Beverly A1 - Sushch, Iurii A1 - Takahashi, T. A1 - Tavernet, J. -P. A1 - Tavernier, T. A1 - Taylor, A. M. A1 - Terrier, R. A1 - Tibaldo, L. A1 - Tiziani, D. A1 - Tluczykont, M. A1 - Trichard, C. A1 - Tsirou, M. A1 - Tsuji, N. A1 - Tuffs, R. A1 - Uchiyama, Y. A1 - van der Walt, D. J. A1 - van Eldik, C. A1 - van Rensburg, C. A1 - van Soelen, B. A1 - Vasileiadis, G. A1 - Veh, J. A1 - Venter, C. A1 - Viana, A. A1 - Vincent, P. A1 - Vink, J. A1 - Voisin, F. A1 - Voelk, H. J. A1 - Vuillaume, T. A1 - Wadiasingh, Z. A1 - Wagner, S. J. A1 - Wagner, P. A1 - Wagner, R. M. A1 - White, R. A1 - Wierzcholska, A. A1 - Willmann, P. A1 - Woernlein, A. A1 - Wouters, D. A1 - Yang, R. A1 - Zaborov, D. A1 - Zacharias, M. A1 - Zanin, R. A1 - Zdziarski, A. A. A1 - Zech, Alraune A1 - Zefi, F. A1 - Ziegler, A. A1 - Zorn, J. A1 - Zywucka, N. T1 - TeV Gamma-Ray Observations of the Binary Neutron Star Merger GW170817 with HESS JF - The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters N2 - We search for high-energy gamma-ray emission from the binary neutron star merger GW170817 with the H.E.S.S. Imaging Air Cherenkov Telescopes. The observations presented here have been obtained starting only 5.3 hr after GW170817. The H.E.S.S. target selection identified regions of high probability to find a counterpart of the gravitational-wave event. The first of these regions contained the counterpart SSS17a that has been identified in the optical range several hours after our observations. We can therefore present the first data obtained by a ground-based pointing instrument on this object. A subsequent monitoring campaign with the H.E.S.S. telescopes extended over several days, covering timescales from 0.22 to 5.2 days and energy ranges between 270 GeV to 8.55 TeV. No significant gamma-ray emission has been found. The derived upper limits on the very-high-energy gamma-ray flux for the first time constrain non-thermal, high-energy emission following the merger of a confirmed binary neutron star system. KW - gamma-ray burst: individual (GRB 170817A) KW - gamma rays: general KW - gravitational waves Y1 - 2017 U6 - https://doi.org/10.3847/2041-8213/aa97d2 SN - 2041-8205 SN - 2041-8213 VL - 850 SP - 628 EP - 650 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Heinzel, Stephan A1 - Lorenz, Robert C. A1 - Quynh-Lam Duong, A1 - Rapp, Michael A. A1 - Deserno, Lorenz T1 - Prefrontal-parietal effective connectivity during working memory in older adults JF - Neurobiology of Aging N2 - Theoretical models and preceding studies have described age-related alterations in neuronal activation of frontoparietal regions in a working memory (WM)load-dependent manner. However, to date, underlying neuronal mechanisms of these WM load-dependent activation changes in aging remain poorly understood. The aim of this study was to investigate these mechanisms in terms of effective connectivity by application of dynamic causal modeling with Bayesian Model Selection. Eighteen healthy younger (age: 20-32 years) and 32 older (60-75 years) participants performed an n-back task with 3 WM load levels during functional magnetic resonance imaging (fMRI). Behavioral and conventional fMRI results replicated age group by WM load interactions. Importantly, the analysis of effective connectivity derived from dynamic causal modeling, indicated an age-and performance-related reduction in WM load-dependent modulation of connectivity from dorsolateral prefrontal cortex to inferior parietal lobule. This finding provides evidence for the proposal that age-related WM decline manifests as deficient WM load-dependent modulation of neuronal top-down control and can integrate implications from theoretical models and previous studies of functional changes in the aging brain. KW - Aging KW - Dynamic causal modeling (DCM) KW - Effective connectivity KW - Functional magnetic resonance imaging (fMRI) KW - Working memory Y1 - 2017 U6 - https://doi.org/10.1016/j.neurobiolaging.2017.05.005 SN - 0197-4580 SN - 1558-1497 VL - 57 SP - 18 EP - 27 PB - Elsevier CY - New York ER - TY - JOUR A1 - Abdalla, H. A1 - Abramowski, A. A1 - Aharonian, Felix A. A1 - Benkhali, F. Ait A1 - Akhperjanian, A. G. A1 - Andersson, T. A1 - Anguener, E. O. A1 - Arrieta, M. A1 - Aubert, P. A1 - Backes, M. A1 - Balzer, A. A1 - Barnard, M. A1 - Becherini, Y. A1 - Tjus, J. Becker A1 - Berge, D. A1 - Bernhard, S. A1 - Bernlorhr, K. A1 - Blackwell, R. A1 - Bottcher, M. A1 - Boisson, C. A1 - Bolmont, J. A1 - Bordas, Pol A1 - Bregeon, J. A1 - Brun, F. A1 - Brun, P. A1 - Bryan, M. A1 - Bulik, T. A1 - Capasso, M. A1 - Carr, J. A1 - Casanova, Sabrina A1 - Cerruti, M. A1 - Chakraborty, N. A1 - Chalme-Calvet, R. A1 - Chaves, R. C. G. A1 - Chen, A. A1 - Chevalier, J. A1 - Chretien, M. A1 - Colafrancesco, S. A1 - Cologna, G. A1 - Condon, B. A1 - Conrad, J. A1 - Cui, Y. A1 - Davids, I. D. A1 - Decock, J. A1 - Degrange, B. A1 - Deil, C. A1 - Devin, J. A1 - deWilt, P. A1 - Dirson, L. A1 - Djannati-Atai, A. A1 - Domainko, W. A1 - Donath, A. A1 - Dubus, G. A1 - Dutson, K. A1 - Dyks, J. A1 - Edwards, T. A1 - Egberts, Kathrin A1 - Eger, P. A1 - Ernenwein, J. -P. A1 - Eschbach, S. A1 - Farnier, C. A1 - Fegan, S. A1 - Fernandes, M. V. A1 - Fiasson, A. A1 - Fontaine, G. A1 - Foerster, A. A1 - Funk, S. A1 - Fuessling, M. A1 - Gabici, S. A1 - Gajdus, M. A1 - Gallant, Y. A. A1 - Garrigoux, T. A1 - Giavitto, G. A1 - Giebels, B. A1 - Glicenstein, J. F. A1 - Gottschall, D. A1 - Goyal, A. A1 - Grondin, M. -H. A1 - Hadasch, D. A1 - Hahn, J. A1 - Haupt, M. A1 - Hawkes, J. A1 - Heinzelmann, G. A1 - Henri, G. A1 - Hermann, G. A1 - Hervet, O. A1 - Hinton, J. A. A1 - Hofmann, W. A1 - Hoischen, Clemens A1 - Holler, M. A1 - Horns, D. A1 - Ivascenko, A. A1 - Jacholkowska, A. A1 - Jamrozy, M. A1 - Janiak, M. A1 - Jankowsky, D. A1 - Jankowsky, F. A1 - Jingo, M. A1 - Jogler, T. A1 - Jouvin, L. A1 - Jung-Richardt, I. A1 - Kastendieck, M. A. A1 - Katarzynski, K. A1 - Katz, U. A1 - Kerszberg, D. A1 - Khelifi, B. A1 - Er, M. Kie Ff A1 - King, J. A1 - Klepser, S. A1 - Klochkov, D. A1 - Kluzniak, W. A1 - Kolitzus, D. A1 - Komin, Nu. A1 - Kosack, K. A1 - Krakau, S. A1 - Kraus, M. A1 - Krayzel, F. A1 - Kruger, P. P. A1 - Laffon, H. A1 - Lamanna, G. A1 - Lau, J. A1 - Lees, J. -P. A1 - Lefaucheur, J. A1 - Lefranc, V. A1 - Lemiere, A. A1 - Lemoine-Goumard, M. A1 - Lenain, J. -P. A1 - Leser, E. A1 - Lohse, T. A1 - Lorentz, M. A1 - Liu, R. A1 - Lopez-Coto, R. A1 - Lypova, I. A1 - Marandon, V. A1 - Marcowith, Alexandre A1 - Mariaud, C. A1 - Marx, R. A1 - Maurin, G. A1 - Maxted, N. A1 - Mayer, M. A1 - Meintjes, P. J. A1 - Meyer, M. A1 - Mitchell, A. M. W. A1 - Moderski, R. A1 - Mohamed, M. A1 - Mohrmann, L. A1 - Mora, K. A1 - Moulin, Emmanuel A1 - Murach, T. A1 - de Naurois, M. A1 - Niederwanger, F. A1 - Niemiec, J. A1 - Oakes, L. A1 - Odaka, H. A1 - Oettl, S. A1 - Ohm, S. A1 - Ostrowski, M. A1 - Oya, I. A1 - Padovani, M. A1 - Panter, M. A1 - Parsons, R. D. A1 - Pekeur, N. W. A1 - Pelletier, G. A1 - Perennes, C. A1 - Petrucci, P. -O. A1 - Peyaud, B. A1 - Piel, Q. A1 - Pita, S. A1 - Poon, H. A1 - Prokhorov, D. A1 - Prokoph, H. A1 - Puehlhofer, G. A1 - Punch, M. A1 - Quirrenbach, A. A1 - Raab, S. A1 - Reimer, A. A1 - Reimer, O. A1 - Renaud, M. A1 - de los Reyes, R. A1 - Rieger, F. A1 - Romoli, C. A1 - Rosier-Lees, S. A1 - Rowell, G. A1 - Rudak, B. A1 - Rulten, C. B. A1 - Sahakian, V. A1 - Salek, D. A1 - Sanchez, D. A. A1 - Santangelo, Andrea A1 - Sasaki, M. A1 - Schlickeiser, R. A1 - Schussler, F. A1 - Schulz, A. A1 - Schwanke, U. A1 - Schwemmer, S. A1 - Settimo, M. A1 - Seyffert, A. S. A1 - Shafi, N. A1 - Shilon, I. A1 - Simoni, R. A1 - Sol, H. A1 - Spanier, F. A1 - Spengler, G. A1 - Spies, F. A1 - Ert, Ff A1 - Stawarz, L. A1 - Steenkamp, R. A1 - Stegmann, Christian Michael A1 - Stinzing, F. A1 - Stycz, K. A1 - Sushch, I. A1 - Tavernet, J. -P. A1 - Tavernier, T. A1 - Taylor, A. M. A1 - Terrier, R. A1 - Tibaldo, L. A1 - Tiziani, D. A1 - Tluczykont, M. A1 - Trichard, C. A1 - Tuffs, R. A1 - Uchiyama, Y. A1 - van der Walt, D. J. A1 - van Eldik, C. A1 - van Rensburg, C. A1 - van Soelen, B. A1 - Vasileiadis, G. A1 - Veh, J. A1 - Venter, C. A1 - Viana, A. A1 - Vincent, P. A1 - Vink, J. A1 - Voisin, F. A1 - Voelk, H. J. A1 - Vuillaume, T. A1 - Wadiasingh, Z. A1 - Wagner, S. J. A1 - Wagner, P. A1 - Wagner, R. M. A1 - White, R. A1 - Wierzcholska, A. A1 - Willmann, P. A1 - Woernlein, A. A1 - Wouters, D. A1 - Yang, R. A1 - Zabalza, V. A1 - Zaborov, D. A1 - Zacharias, M. A1 - Zdziarski, A. A. A1 - Zech, Alraune A1 - Zefi, F. A1 - Ziegler, A. A1 - Zywucka, N. T1 - Characterizing the gamma-ray long-term variability of PKS2155 304 with HESS and Fermi-LAT JF - Astronomy and astrophysics : an international weekly journal N2 - Studying the temporal variability of BL Lac objects at the highest energies provides unique insights into the extreme physical processes occurring in relativistic jets and in the vicinity of super-massive black holes. To this end, the long-term variability of the BL Lac object PKS 2155 304 is analyzed in the high (HE, 100MeV < E < 300 GeV) and very high energy (VHE, E > 200 GeV) gamma-ray domain. Over the course of similar to 9 yr of H. E. S. S. observations the VHE light curve in the quiescent state is consistent with a log-normal behavior. The VHE variability in this state is well described by flicker noise (power-spectral-density index beta(VHE) = 1 .10(+ 0 : 10) (0 : 13)) on timescales larger than one day. An analysis of similar to 5.5 yr of HE Fermi-LAT data gives consistent results (beta(HE) = 1 : 20(+ 0 : 21) (0 : 23), on timescales larger than 10 days) compatible with the VHE findings. The HE and VHE power spectral densities show a scale invariance across the probed time ranges. A direct linear correlation between the VHE and HE fluxes could neither be excluded nor firmly established. These long-term-variability properties are discussed and compared to the red noise behavior (beta similar to 2) seen on shorter timescales during VHE-flaring states. The difference in power spectral noise behavior at VHE energies during quiescent and flaring states provides evidence that these states are influenced by different physical processes, while the compatibility of the HE and VHE long-term results is suggestive of a common physical link as it might be introduced by an underlying jet-disk connection. KW - galaxies: active KW - BL Lacertae objects: individual: PKS 2155-304 KW - gamma rays: galaxies KW - galaxies: jets KW - galaxies: nuclei KW - radiation mechanisms: non-thermal Y1 - 2017 U6 - https://doi.org/10.1051/0004-6361/201629419 SN - 1432-0746 SN - 0004-6361 VL - 598 PB - EDP Sciences CY - Les Ulis ER -