TY - JOUR A1 - Groop, Per-Henrik A1 - Cooper, Mark E. A1 - Perkovic, Vlado A1 - Hocher, Berthold A1 - Kanasaki, Keizo A1 - Haneda, Masakazu A1 - Schernthaner, Guntram A1 - Sharma, Kumar A1 - Stanton, Robert C. A1 - Toto, Robert A1 - Cescutti, Jessica A1 - Gordat, Maud A1 - Meinicke, Thomas A1 - Koitka-Weber, Audrey A1 - Thiemann, Sandra A1 - von Eynatten, Maximilian T1 - Linagliptin and its effects on hyperglycaemia and albuminuria in patients with type 2 diabetes and renal dysfunction BT - the randomized MARLINA-T2D trial JF - Diabetes obesity & metabolism : a journal of pharmacology and therapeutics N2 - Aims: The MARLINA-T2D study (ClinicalTrials. gov, NCT01792518) was designed to investigate the glycaemic and renal effects of linagliptin added to standard-of-care in individuals with type 2 diabetes and albuminuria. Methods: A total of 360 individuals with type 2 diabetes, HbA1c 6.5% to 10.0% (48-86 mmol/ mol), estimated glomerular filtration rate (eGFR) >= 30 mL/min/1.73 m(2) and urinary albumin-tocreatinine ratio (UACR) 30-3000 mg/g despite single agent renin-angiotensin-system blockade were randomized to double-blind linagliptin (n = 182) or placebo (n = 178) for 24 weeks. The primary and key secondary endpoints were change from baseline in HbA1c at week 24 and time-weighted average of percentage change from baseline in UACR over 24 weeks, respectively. Results: Baseline mean HbA1c and geometric mean (gMean) UACR were 7.8% +/- 0.9% (62.2 +/- 9.6 mmol/mol) and 126 mg/g, respectively; 73.7% and 20.3% of participants had microalbuminuria or macroalbuminuria, respectively. After 24 weeks, the placebo-adjusted mean change in HbA1c from baseline was -0.60% (-6.6 mmol/mol) (95% confidence interval [CI], -0.78 to -0.43 [-8.5 to -4.7 mmol/mol]; P <.0001). The placebo-adjusted gMean for time-weighted average of percentage change in UACR from baseline was -6.0% (95% CI, -15.0 to 3.0; P =.1954). The adverse-event profile, including renal safety and change in eGFR, was similar between the linagliptin and placebo groups. Conclusions: In individuals at early stages of diabetic kidney disease, linagliptin significantly improved glycaemic control but did not significantly lower albuminuria. There was no significant change in placebo-adjusted eGFR. Detection of clinically relevant renal effects of linagliptin may require longer treatment, as its main experimental effects in animal studies have been to reduce interstitial fibrosis rather than alter glomerular haemodynamics. KW - antidiabetic drug KW - clinical trial KW - diabetic nephropathy KW - DPP-IV inhibitor KW - glycaemic control KW - linagliptin Y1 - 2017 U6 - https://doi.org/10.1111/dom.13041 SN - 1462-8902 SN - 1463-1326 VL - 19 IS - 11 SP - 1610 EP - 1619 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Sier, Mark J. A1 - Langereis, Cor G. A1 - Dupont-Nivet, Guillaume A1 - Feibel, Craig S. A1 - Joordens, Josephine C. A. A1 - van der Lubbe, Jeroen Fiji. A1 - Beck, Catherine C. A1 - Olago, Daniel A1 - Cohen, Andrew T1 - The top of the Olduvai Subchron in a high-resolution magnetostratigraphy from the West Turkana core WTK13, hominin sites and Paleolakes Drilling Project (HSPDP) JF - Quaternary geochronology : the international research and review journal on advances in quaternary dating techniques N2 - One of the major challenges in understanding the evolution of our own species is identifying the role climate change has played in the evolution of hominin species. To clarify the influence of climate, we need long and continuous high-resolution paleoclimate records, preferably obtained from hominin-bearing sediments, that are well-dated by tephro- and magnetostratigraphy and other methods. This is hindered, however, by the fact that fossil-bearing outcrop sediments are often discontinuous, and subject to weathering, which may lead to oxidation and remagnetization. To obtain fresh, unweathered sediments, the Hominin Sites and Paleolakes Drilling Project (HSPDP) collected a ∼216-meter core (WTK13) in 2013 from Early Pleistocene Paleolake Lorenyang deposits in the western Turkana Basin (Kenya). Here, we present the magnetostratigraphy of the WTK13 core, providing a first age model for upcoming HSPDP paleoclimate and paleoenvrionmental studies on the core sediments. Rock magnetic analyses reveal the presence of iron sulfides carrying the remanent magnetizations. To recover polarity orientation from the near-equatorial WTK13 core drilled at 5°N, we developed and successfully applied two independent drill-core reorientation methods taking advantage of (1) the sedimentary fabric as expressed in the Anisotropy of Magnetic Susceptibility (AMS) and (2) the occurrence of a viscous component oriented in the present day field. The reoriented directions reveal a normal to reversed polarity reversal identified as the top of the Olduvai Subchron. From this excellent record, we find no evidence for the ‘Vrica Subchron’ previously reported in the area. We suggest that outcrop-based interpretations supporting the presence of the Vrica Subchron have been affected by the oxidation of iron sulfides initially present in the sediments -as evident in the core record- and by subsequent remagnetization. We discuss the implications of the observed geomagnetic record for human evolution studies. KW - Paleolake Lorenyang KW - Magnetostratigraphy KW - Olduvai Subchron KW - Vrica Subchron KW - Drill-core reorientation KW - ICDP KW - Paleoclimate KW - Hominin evolution Y1 - 2017 U6 - https://doi.org/10.1016/j.quageo.2017.08.004 SN - 1871-1014 SN - 1878-0350 VL - 42 SP - 117 EP - 129 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Rach, Oliver A1 - Engels, S. A1 - Kahmen, A. A1 - Brauer, Achim A1 - Martin-Puertas, C. A1 - van Geel, B. A1 - Sachse, Dirk T1 - Hydrological and ecological changes in western Europe between 3200 and 2000 years BP derived from lipid biomarker delta D values in lake Meerfelder Maar sediments JF - Quaternary science reviews : the international multidisciplinary research and review journal N2 - One of the most significant Late Holocene climate shifts occurred around 2800 years ago, when cooler and wetter climate conditions established in western Europe. This shift coincided with an abrupt change in regional atmospheric circulation between 2760 and 2560 cal years BP, which has been linked to a grand solar minimum with the same duration (the Homeric Minimum). We investigated the temporal sequence of hydroclimatic and vegetation changes across this interval of climatic change (Homeric climate oscillation) by using lipid biomarker stable hydrogen isotope ratios (ED values) and pollen assemblages from the annually-laminated sediment record from lake Meerfelder Maar (Germany). Over the investigated interval (3200-2000 varve years BP), terrestrial lipid biomarker ED showed a gradual trend to more negative values, consistent with the western Europe long-term climate trend of the Late Holocene. At ca. 2640 varve years BP we identified a strong increase in aquatic plants and algal remains, indicating a rapid change in the aquatic ecosystem superimposed on this long-term trend. Interestingly, this aquatic ecosystem change was accompanied by large changes in ED values of aquatic lipid biomarkers, such as nC(21) and nC(23) (by between 22 and 30%(0)). As these variations cannot solely be explained by hydroclimate changes, we suggest that these changes in the Wag value were influenced by changes in n-alkane source organisms. Our results illustrate that if ubiquitous aquatic lipid biomarkers are derived from a limited pool of organisms, changes in lake ecology can be a driving factor for variations on sedimentary lipid MN values, which then could be easily misinterpreted in terms of hydro climatic changes. (C) 2017 Elsevier Ltd. All rights reserved. KW - Holocene KW - Climate dynamics KW - Paleoclimatology KW - Western Europe KW - Continental biomarkers KW - Organic geochemistry KW - Stable isotopes KW - Vegetation dynamics Y1 - 2017 U6 - https://doi.org/10.1016/j.quascirev.2017.07.019 SN - 0277-3791 VL - 172 SP - 44 EP - 54 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Schütze, Franziska A1 - Fürst, Steffen A1 - Mielke, Jahel A1 - Steudle, Gesine A. A1 - Wolf, Sarah A1 - Jäger, Carlo C. T1 - The Role of Sustainable Investment in Climate Policy JF - Sustainability N2 - Reaching the Sustainable Development Goals requires a fundamental socio-economic transformation accompanied by substantial investment in low-carbon infrastructure. Such a sustainability transition represents a non-marginal change, driven by behavioral factors and systemic interactions. However, typical economic models used to assess a sustainability transition focus on marginal changes around a local optimum, whichby constructionlead to negative effects. Thus, these models do not allow evaluating a sustainability transition that might have substantial positive effects. This paper examines which mechanisms need to be included in a standard computable general equilibrium model to overcome these limitations and to give a more comprehensive view of the effects of climate change mitigation. Simulation results show that, given an ambitious greenhouse gas emission constraint and a price of carbon, positive economic effects are possible if (1) technical progress results (partly) endogenously from the model and (2) a policy intervention triggering an increase of investment is introduced. Additionally, if (3) the investment behavior of firms is influenced by their sales expectations, the effects are amplified. The results provide suggestions for policy-makers, because the outcome indicates that investment-oriented climate policies can lead to more desirable outcomes in economic, social and environmental terms. KW - climate policy KW - green growth KW - macroeconomic models KW - sustainable investment KW - technical progress KW - expectations KW - 1.5 degrees C Y1 - 2017 U6 - https://doi.org/10.3390/su9122221 SN - 2071-1050 VL - 9 PB - MDPI CY - Basel ER - TY - JOUR A1 - García-Camacho, Raúl A1 - Metz, Johannes A1 - Bilton, Mark C. A1 - Tielboerger, Katja T1 - Phylogenetic structure of annual plant communities along an aridity gradient BT - Interacting effects of habitat filtering and shifting plant-plant interactions JF - Israel Journal of Plant Sciences N2 - The phylogenetic structure of communities (PSC) reveals how evolutionary history affects community assembly processes. However, there are important knowledge gaps on PSC patterns for annual communities and there is a need for studies along environmental gradients in dry ecosystems where several processes shape PSC. Here, we investigated the PSC of annual plants along an aridity gradient in Israel, including eight years, two spatial scales, the effects of shrubs on understory, and the phylogenetic signal of important traits. Increasing drought stress led to overdispersed PSC at the drier end of the gradient, indicating that species were less related than expected by chance. This was supported at a smaller spatial scale, where within the drier sites, communities in open- more arid- habitats were more overdispersed than those under nurse shrubs. Interestingly, some key traits related to drought resistance were not conserved in the phylogeny. Together, our findings suggested that while habitat filtering selected for drought resistance strategies, these strategies evolved independently along multiple contrasting evolutionary lineages. Our comprehensive PSC study provides strong evidence for the interacting effects of habitat filtering and plant- plant interactions, particularly highlighting that the conservative evolution of traits should not be assumed in future interpretations of PSC patterns. KW - Annuals KW - aridity gradient KW - community assembly rules KW - community phylogenetics KW - stress-gradient hypothesis KW - trait phylogenetic conservatism Y1 - 2017 U6 - https://doi.org/10.1080/07929978.2017.1288477 SN - 0792-9978 SN - 2223-8980 VL - 64 IS - 1-2 SP - 122 EP - 134 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Dominguez, Marisol A1 - Tiedemann, Ralph A1 - Reboreda, Juan C. A1 - Segura, Luciano A1 - Tittarelli, Fabian A1 - Mahler, Bettina T1 - Genetic structure reveals management units for the yellow cardinal (Gubernatrix cristata), endangered by habitat loss and illegal trapping JF - Conservation genetics KW - Genetic structure KW - Gubernatrix cristata KW - Management units KW - MtDNA KW - Microsatellites KW - Hybrids Y1 - 2017 U6 - https://doi.org/10.1007/s10592-017-0964-4 SN - 1566-0621 SN - 1572-9737 VL - 18 SP - 1131 EP - 1140 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Morf, Carolyn C. A1 - Schurch, Eva A1 - Kufener, Albrecht A1 - Siegrist, Philip A1 - Vater, Aline A1 - Back, Mitja A1 - Mestel, Robert A1 - Schröder-Abe, Michela T1 - Expanding the Nomological Net of the Pathological Narcissism Inventory: German Validation and Extension in a Clinical Inpatient Sample JF - Assessment KW - narcissism KW - assessment KW - Pathological Narcissism Inventory KW - construct validity KW - nomological network Y1 - 2017 U6 - https://doi.org/10.1177/1073191115627010 SN - 1073-1911 SN - 1552-3489 VL - 24 SP - 419 EP - 443 PB - Sage Publ. CY - Thousand Oaks ER - TY - GEN A1 - Schütze, Franziska A1 - Fürst, Steffen A1 - Mielke, Jahel A1 - Steudle, Gesine A. A1 - Wolf, Sarah A1 - Jäger, Carlo C. T1 - The Role of Sustainable Investment in Climate Policy T2 - Postprints der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe N2 - Reaching the Sustainable Development Goals requires a fundamental socio-economic transformation accompanied by substantial investment in low-carbon infrastructure. Such a sustainability transition represents a non-marginal change, driven by behavioral factors and systemic interactions. However, typical economic models used to assess a sustainability transition focus on marginal changes around a local optimum, whichby constructionlead to negative effects. Thus, these models do not allow evaluating a sustainability transition that might have substantial positive effects. This paper examines which mechanisms need to be included in a standard computable general equilibrium model to overcome these limitations and to give a more comprehensive view of the effects of climate change mitigation. Simulation results show that, given an ambitious greenhouse gas emission constraint and a price of carbon, positive economic effects are possible if (1) technical progress results (partly) endogenously from the model and (2) a policy intervention triggering an increase of investment is introduced. Additionally, if (3) the investment behavior of firms is influenced by their sales expectations, the effects are amplified. The results provide suggestions for policy-makers, because the outcome indicates that investment-oriented climate policies can lead to more desirable outcomes in economic, social and environmental terms. T3 - Zweitveröffentlichungen der Universität Potsdam : Wirtschafts- und Sozialwissenschaftliche Reihe - 137 KW - climate policy KW - green growth KW - macroeconomic models KW - sustainable investment KW - technical progress KW - expectations KW - 1.5 degrees C Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-470485 SN - 1867-5808 IS - 137 ER - TY - JOUR A1 - Estendorfer, Jennifer A1 - Stempfhuber, Barbara A1 - Haury, Paula A1 - Vestergaard, Gisle A1 - Rillig, Matthias C. A1 - Joshi, Jasmin Radha A1 - Schröder, Peter A1 - Schloter, Michael T1 - The Influence of Land Use Intensity on the Plant-Associated Microbiome of Dactylis glomerata L. JF - Frontiers in plant science N2 - In this study, we investigated the impact of different land use intensities (LUI) on the root-associated microbiome of Dactylis glomerata (orchardgrass). For this purpose, eight sampling sites with different land use intensity levels but comparable soil properties were selected in the southwest of Germany. Experimental plots covered land use levels from natural grassland up to intensively managed meadows. We used 16S rRNA gene based barcoding to assess the plant-associated community structure in the endosphere, rhizosphere and bulk soil of D. glomerata. Samples were taken at the reproductive stage of the plant in early summer. Our data indicated that roots harbor a distinct bacterial community, which clearly differed from the microbiome of the rhizosphere and bulk soil. Our results revealed Pseudomonadaceae, Enterobacteriaceae and Comamonadaceae as the most abundant endophytes independently of land use intensity. Rhizosphere and bulk soil were dominated also by Proteobacteria, but the most abundant families differed from those obtained from root samples. In the soil, the effect of land use intensity was more pronounced compared to root endophytes leading to a clearly distinct pattern of bacterial communities under different LUI from rhizosphere and bulk soil vs. endophytes. Overall, a change of community structure on the plant-soil interface was observed, as the number of shared OTUs between all three compartments investigated increased with decreasing land use intensity. Thus, our findings suggest a stronger interaction of the plant with its surrounding soil under low land use intensity. Furthermore, the amount and quality of available nitrogen was identified as a major driver for shifts in the microbiome structure in all compartments. KW - Dactylis glomerata KW - land use change KW - endophytes KW - rhizosphere KW - soil microbiome KW - biodiversity Y1 - 2017 U6 - https://doi.org/10.3389/fpls.2017.00930 SN - 1664-462X VL - 8 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Ahnen, M. L. A1 - Ansoldi, S. A1 - Antonelli, L. A. A1 - Antoranz, P. A1 - Babic, A. A1 - Banerjee, B. A1 - Bangale, P. A1 - de Almeida, U. Barres A1 - Barrio, J. A. A1 - Gonzalez, J. Becerra A1 - Bednarek, W. A1 - Bernardini, E. A1 - Berti, A. A1 - Biasuzzi, B. A1 - Biland, A. A1 - Blanch, O. A1 - Bonnefoy, S. A1 - Bonnoli, G. A1 - Borracci, F. A1 - Bretz, T. A1 - Buson, S. A1 - Carosi, A. A1 - Chatterjee, A. A1 - Clavero, R. A1 - Colin, P. A1 - Colombo, E. A1 - Contreras, J. L. A1 - Cortina, J. A1 - Covino, S. A1 - Da Vela, P. A1 - Dazzi, F. A1 - De Angelis, A. A1 - De Lotto, B. A1 - Wilhelmi, E. de Ona A1 - Di Pierro, F. A1 - Doert, M. A1 - Dominguez, A. A1 - Prester, D. Dominis A1 - Dorner, D. A1 - Doro, M. A1 - Einecke, S. A1 - Glawion, D. Eisenacher A1 - Elsaesser, D. A1 - Engelkemeier, M. A1 - Ramazani, V. Fallah A1 - Fernandez-Barral, A. A1 - Fidalgo, D. A1 - Fonseca, M. V. A1 - Font, L. A1 - Frantzen, K. A1 - Fruck, C. A1 - Galindo, D. A1 - Lopez, R. J. Garcia A1 - Garczarczyk, M. A1 - Terrats, D. Garrido A1 - Gaug, M. A1 - Giammaria, P. A1 - Godinovic, N. A1 - Gonzalez Munoz, A. A1 - Gora, D. A1 - Guberman, D. A1 - Hadasch, D. A1 - Hahn, A. A1 - Hanabata, Y. A1 - Hayashida, M. A1 - Herrera, J. A1 - Hose, J. A1 - Hrupec, D. A1 - Hughes, G. A1 - Idec, W. A1 - Kodani, K. A1 - Konno, Y. A1 - Kubo, H. A1 - Kushida, J. A1 - La Barbera, A. A1 - Lelas, D. A1 - Lindfors, E. A1 - Lombardi, S. A1 - Longo, F. A1 - Lopez, M. A1 - Lopez-Coto, R. A1 - Majumdar, P. A1 - Makariev, M. A1 - Mallot, K. A1 - Maneva, G. A1 - Manganaro, M. A1 - Mannheim, K. A1 - Maraschi, L. A1 - Marcote, B. A1 - Mariotti, M. A1 - Martinez, M. A1 - Mazin, D. A1 - Menzel, U. A1 - Miranda, J. M. A1 - Mirzoyan, R. A1 - Moralejo, A. A1 - Moretti, E. A1 - Nakajima, D. A1 - Neustroev, V. A1 - Niedzwiecki, A. A1 - Rosillo, M. Nievas A1 - Nilsson, K. A1 - Nishijima, K. A1 - Noda, K. A1 - Nogues, L. A1 - Overkemping, A. A1 - Paiano, S. A1 - Palacio, J. A1 - Palatiello, M. A1 - Paneque, D. A1 - Paoletti, R. A1 - Paredes, J. M. A1 - Paredes-Fortuny, X. A1 - Pedaletti, G. A1 - Peresano, M. A1 - Perri, L. A1 - Persic, M. A1 - Poutanen, J. A1 - Moroni, P. G. Prada A1 - Prandini, E. A1 - Puljak, I. A1 - Reichardt, I. A1 - Rhode, W. A1 - Ribo, M. A1 - Rico, J. A1 - Rodriguez Garcia, J. A1 - Saito, T. A1 - Satalecka, K. A1 - Schroder, S. A1 - Schultz, C. A1 - Schweizer, T. A1 - Shore, S. N. A1 - Sillanpaa, A. A1 - Sitarek, J. A1 - Snidaric, I. A1 - Sobczynska, D. A1 - Stamerra, A. A1 - Steinbring, T. A1 - Strzys, M. A1 - Suric, T. A1 - Takalo, L. A1 - Tavecchio, F. A1 - Temnikov, P. A1 - Terzic, T. A1 - Tescaro, D. A1 - Teshima, M. A1 - Thaele, J. A1 - Torres, D. F. A1 - Toyama, T. A1 - Treves, A. A1 - Vanzo, G. A1 - Verguilov, V. A1 - Vovk, I. A1 - Ward, J. E. A1 - Will, M. A1 - Wu, M. H. A1 - Zanin, R. A1 - Abeysekara, A. U. A1 - Archambault, S. A1 - Archer, A. A1 - Benbow, W. A1 - Bird, R. A1 - Buchovecky, M. A1 - Buckley, J. H. A1 - Bugaev, V. A1 - Connolly, M. P. A1 - Cui, W. A1 - Dickinson, H. J. A1 - Falcone, A. A1 - Feng, Q. A1 - Finley, J. P. A1 - Fleischhack, H. A1 - Flinders, A. A1 - Fortson, L. A1 - Gillanders, G. H. A1 - Griffin, S. A1 - Grube, J. A1 - Huetten, M. A1 - Hanna, D. A1 - Holder, J. A1 - Humensky, T. B. A1 - Kaaret, P. A1 - Kar, P. A1 - Kelley-Hoskins, N. A1 - Kertzman, M. A1 - Kieda, D. A1 - Krause, M. A1 - Krennrich, F. A1 - Lang, M. J. A1 - Maier, G. A1 - McCann, A. A1 - Moriarty, P. A1 - Mukherjee, R. A1 - Nieto, D. A1 - Ong, R. A. A1 - Otte, N. A1 - Park, N. A1 - Perkins, J. A1 - Pichel, A. A1 - Pohl, M. A1 - Popkow, A. A1 - Pueschel, Elisa A1 - Quinn, J. A1 - Ragan, K. A1 - Reynolds, P. T. A1 - Richards, G. T. A1 - Roache, E. A1 - Rovero, A. C. A1 - Rulten, C. A1 - Sadeh, I. A1 - Santander, M. A1 - Sembroski, G. H. A1 - Shahinyan, K. A1 - Telezhinsky, Igor O. A1 - Tucci, J. V. A1 - Tyler, J. A1 - Wakely, S. P. A1 - Weinstein, A. A1 - Wilcox, P. A1 - Wilhelm, Alina A1 - Williams, D. A. A1 - Zitzer, B. A1 - Razzaque, S. A1 - Villata, M. A1 - Raiteri, C. M. A1 - Aller, H. D. A1 - Aller, M. F. A1 - Larionov, V. M. A1 - Arkharov, A. A. A1 - Blinov, D. A. A1 - Efimova, N. V. A1 - Grishina, T. S. A1 - Hagen-Thorn, V. A. A1 - Kopatskaya, E. N. A1 - Larionova, L. V. A1 - Larionova, E. G. A1 - Morozova, D. A. A1 - Troitsky, I. S. A1 - Ligustri, R. A1 - Calcidese, P. A1 - Berdyugin, A. A1 - Kurtanidze, O. M. A1 - Nikolashvili, M. G. A1 - Kimeridze, G. N. A1 - Sigua, L. A. A1 - Kurtanidze, S. O. A1 - Chigladze, R. A. A1 - Chen, W. P. A1 - Koptelova, E. A1 - Sakamoto, T. A1 - Sadun, A. C. A1 - Moody, J. W. A1 - Pace, C. A1 - Pearson, R. A1 - Yatsu, Y. A1 - Mori, Y. A1 - Carraminyana, A. A1 - Carrasco, L. A1 - de la Fuente, E. A1 - Norris, J. P. A1 - Smith, P. S. A1 - Wehrle, A. A1 - Gurwell, M. A. A1 - Zook, A. A1 - Pagani, C. A1 - Perri, M. A1 - Capalbi, M. A1 - Cesarini, A. A1 - Krimm, H. A. A1 - Kovalev, Y. Y. A1 - Kovalev, Yu. A. A1 - Ros, E. A1 - Pushkarev, A. B. A1 - Lister, M. L. A1 - Sokolovsky, K. V. A1 - Kadler, M. A1 - Piner, G. A1 - Lahteenmaki, A. A1 - Tornikoski, M. A1 - Angelakis, E. A1 - Krichbaum, T. P. A1 - Nestoras, I. A1 - Fuhrmann, L. A1 - Zensus, J. A. A1 - Cassaro, P. A1 - Orlati, A. A1 - Maccaferri, G. A1 - Leto, P. A1 - Giroletti, M. A1 - Richards, J. L. A1 - Max-Moerbeck, W. A1 - Readhead, A. C. S. T1 - Multiband variability studies and novel broadband SED modeling of Mrk 501 in 2009 JF - Astronomy and astrophysics : an international weekly journal N2 - Aims. We present an extensive study of the BL Lac object Mrk 501 based on a data set collected during the multi-instrument campaign spanning from 2009 March 15 to 2009 August 1, which includes, among other instruments, MAGIC, VERITAS, Whipple 10 m, and Fermi-LAT to cover the gamma-ray range from 0.1 GeV to 20 TeV; RXTE and Swift to cover wavelengths from UV to hard X-rays; and GASP-WEBT, which provides coverage of radio and optical wavelengths. Optical polarization measurements were provided for a fraction of the campaign by the Steward and St. Petersburg observatories. We evaluate the variability of the source and interband correlations, the gamma-ray flaring activity occurring in May 2009, and interpret the results within two synchrotron self-Compton (SSC) scenarios. Methods. The multiband variability observed during the full campaign is addressed in terms of the fractional variability, and the possible correlations are studied by calculating the discrete correlation function for each pair of energy bands where the significance was evaluated with dedicated Monte Carlo simulations. The space of SSC model parameters is probed following a dedicated grid-scan strategy, allowing for a wide range of models to be tested and offering a study of the degeneracy of model-to-data agreement in the individual model parameters, hence providing a less biased interpretation than the "single-curve SSC model adjustment" typically reported in the literature. Results. We find an increase in the fractional variability with energy, while no significant interband correlations of flux changes are found on the basis of the acquired data set. The SSC model grid-scan shows that the flaring activity around May 22 cannot be modeled adequately with a one-zone SSC scenario (using an electron energy distribution with two breaks), while it can be suitably described within a two (independent) zone SSC scenario. Here, one zone is responsible for the quiescent emission from the averaged 4.5-month observing period, while the other one, which is spatially separated from the first, dominates the flaring emission occurring at X-rays and very-high-energy (> 100 GeV, VHE) gamma-rays. The flaring activity from May 1, which coincides with a rotation of the electric vector polarization angle (EVPA), cannot be satisfactorily reproduced by either a one-zone or a two-independent-zone SSC model, yet this is partially affected by the lack of strictly simultaneous observations and the presence of large flux changes on sub-hour timescales (detected at VHE gamma rays). Conclusions. The higher variability in the VHE emission and lack of correlation with the X-ray emission indicate that, at least during the 4.5-month observing campaign in 2009, the highest energy (and most variable) electrons that are responsible for the VHE gamma rays do not make a dominant contribution to the similar to 1 keV emission. Alternatively, there could be a very variable component contributing to the VHE gamma-ray emission in addition to that coming from the SSC scenario. The studies with our dedicated SSC grid-scan show that there is some degeneracy in both the one-zone and the two-zone SSC scenarios probed, with several combinations of model parameters yielding a similar model-to-data agreement, and some parameters better constrained than others. The observed gamma-ray flaring activity, with the EVPA rotation coincident with the first gamma-ray flare, resembles those reported previously for low frequency peaked blazars, hence suggesting that there are many similarities in the flaring mechanisms of blazars with different jet properties. KW - BL Lacertae objects: individual: Markarian 501 KW - methods: data analysis Y1 - 2017 U6 - https://doi.org/10.1051/0004-6361/201629540 SN - 1432-0746 VL - 603 PB - EDP Sciences CY - Les Ulis ER -