TY  - GEN
A1  - Taubert, Andreas
A1  - Balischewski, Christian
A1  - Hentrich, Doreen
A1  - Elschner, Thomas
A1  - Eidner, Sascha
A1  - Günter, Christina
A1  - Behrens, Karsten
A1  - Heinze, Thomas
T1  - Water-soluble cellulose derivatives are sustainable additives for biomimetic calcium phosphate mineralization
N2  - The effect of cellulose-based polyelectrolytes on biomimetic calcium phosphate mineralization is described. Three cellulose derivatives, a polyanion, a polycation, and a polyzwitterion were used as additives. Scanning electron microscopy, X-ray diffraction, IR and Raman spectroscopy show that, depending on the composition of the starting solution, hydroxyapatite or brushite precipitates form. Infrared and Raman spectroscopy also show that significant amounts of nitrate ions are incorporated in the precipitates. Energy dispersive X-ray spectroscopy shows that the Ca/P ratio varies throughout the samples and resembles that of other bioinspired calcium phosphate hybrid materials. Elemental analysis shows that the carbon (i.e., polymer) contents reach 10% in some samples, clearly illustrating the formation of a true hybrid material. Overall, the data indicate that a higher polymer concentration in the reaction mixture favors the formation of polymer-enriched materials, while lower polymer concentrations or high precursor concentrations favor the formation of products that are closely related to the control samples precipitated in the absence of polymer. The results thus highlight the potential of (water-soluble) cellulose derivatives for the synthesis and design of bioinspired and bio-based hybrid materials.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 354 
KW  - cellulose
KW  - polyamine
KW  - polyammonium salt
KW  - polycarboxylate
KW  - polyzwitterion
KW  - calcium phosphate
KW  - biomineralization
KW  - brushite
KW  - hydroyxapatite
KW  - biomaterial
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-400453
ER  - 
TY  - JOUR
A1  - Taubert, Andreas
A1  - Balischewski, Christian
A1  - Hentrich, Doreen
A1  - Elschner, Thomas
A1  - Eidner, Sascha
A1  - Günter, Christina
A1  - Behrens, Karsten
A1  - Heinze, Thomas
T1  - Water-Soluble Cellulose Derivatives Are Sustainable Additives for Biomimetic Calcium Phosphate Mineralization
JF  - Inorganics : open access journal
N2  - The effect of cellulose-based polyelectrolytes on biomimetic calcium phosphate mineralization is described. Three cellulose derivatives, a polyanion, a polycation, and a polyzwitterion were used as additives. Scanning electron microscopy, X-ray diffraction, IR and Raman spectroscopy show that, depending on the composition of the starting solution, hydroxyapatite or brushite precipitates form. Infrared and Raman spectroscopy also show that significant amounts of nitrate ions are incorporated in the precipitates. Energy dispersive X-ray spectroscopy shows that the Ca/P ratio varies throughout the samples and resembles that of other bioinspired calcium phosphate hybrid materials. Elemental analysis shows that the carbon (i.e., polymer) contents reach 10% in some samples, clearly illustrating the formation of a true hybrid material. Overall, the data indicate that a higher polymer concentration in the reaction mixture favors the formation of polymer-enriched materials, while lower polymer concentrations or high precursor concentrations favor the formation of products that are closely related to the control samples precipitated in the absence of polymer. The results thus highlight the potential of (water-soluble) cellulose derivatives for the synthesis and design of bioinspired and bio-based hybrid materials.
KW  - cellulose
KW  - polyamine
KW  - polyammonium salt
KW  - polycarboxylate
KW  - polyzwitterion
KW  - calcium phosphate
KW  - biomineralization
KW  - brushite
KW  - hydroyxapatite
KW  - biomaterial
Y1  - 2016
U6  - https://doi.org/10.3390/inorganics4040033
SN  - 2304-6740
VL  - 4
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Ugwuja, Chidinma G.
A1  - Adelowo, Olawale O.
A1  - Ogunlaja, Aemere
A1  - Omorogie, Martins O.
A1  - Olukanni, Olumide D.
A1  - Ikhimiukor, Odion O.
A1  - Iermak, Ievgeniia
A1  - Kolawole, Gabriel A.
A1  - Günter, Christina
A1  - Taubert, Andreas
A1  - Bodede, Olusola
A1  - Moodley, Roshila
A1  - Inada, Natalia M.
A1  - Camargo, Andrea S.S. de
A1  - Unuabonah, Emmanuel Iyayi
T1  - Visible-Light-Mediated Photodynamic Water Disinfection @ Bimetallic-Doped Hybrid Clay Nanocomposites
JF  - ACS applied materials & interfaces
N2  - This study reports a new class of photocatalytic hybrid clay nanocomposites prepared from low-cost sources (kaolinite clay and Carica papaya seeds) doped with Zn and Cu salts via a solvothermal process. X-ray diffraction analysis suggests that Cu-doping and Cu/Zn-doping introduce new phases into the crystalline structure of Kaolinite clay, which is linked to the reduced band gap of kaolinite from typically between 4.9 and 8.2 eV to 2.69 eV for Cu-doped and 1.5 eV for Cu/Zn hybrid clay nanocomposites (Nisar, J.; Arhammar, C.; Jamstorp, E.; Ahuja, R. Phys. Rev. B 2011, 84, 075120). In the presence of solar light irradiation, Cu- and Cu/Zn-doped nanocomposites facilitate the electron hole pair separation. This promotes the generation of singlet oxygen which in turn improves the water disinfection efficiencies of these novel nanocomposite materials. The nanocomposite materials were further characterized using high-resolution scanning electron microscopy, fluorimetry, therrnogravimetric analysis, and Raman spectroscopy. The breakthrough times of the nanocomposites for a fixed bed mode of disinfection of water contaminated with 2.32 x 10(7) cfu/mL E. coli ATCC 25922 under solar light irradiation are 25 h for Zn-doped, 30 h for Cu-doped, and 35 h for Cu/Zn-doped nanocomposites. In the presence of multidrug and multimetal resistant strains of E. coli, the breakthrough time decreases significantly. Zn-only doped nanocomposites are not photocatalytically active. In the absence of light, the nanocomposites are still effective in decontaminating water, although less efficient than under solar light irradiation. Electrostatic interaction, metal toxicity, and release of singlet oxygen (only in the Cu-doped and Cu/Zn-doped nanocomposites) are the three disinfection mechanisms by which these nanocomposites disinfect water. A regrowth study indicates the absence of any living E. coli cells in treated water even after 4 days. These data and the long hydraulic times (under gravity) exhibited by these nanocomposites during photodisinfection of water indicate an unusually high potential of these nanocomposites as efficient, affordable, and sustainable point-of-use systems for the disinfection of water in developing countries.
KW  - disinfection
KW  - nanocomposite material
KW  - multidrug-resistant Escherichia coli
KW  - water
KW  - reactive oxygen species
Y1  - 2019
U6  - https://doi.org/10.1021/acsami.9b01212
SN  - 1944-8244
SN  - 1944-8252
VL  - 11
IS  - 28
SP  - 25483
EP  - 25494
PB  - American Chemical Society
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Balischewski, Christian
A1  - Bhattacharyya, Biswajit
A1  - Sperlich, Eric
A1  - Günter, Christina
A1  - Beqiraj, Alkit
A1  - Klamroth, Tillmann
A1  - Behrens, Karsten
A1  - Mies, Stefan
A1  - Kelling, Alexandra
A1  - Lubahn, Susanne
A1  - Holtzheimer, Lea
A1  - Nitschke, Anne
A1  - Taubert, Andreas
T1  - Tetrahalidometallate(II) ionic liquids with more than one metal
BT  - the effect of bromide versus chloride
JF  - Chemistry - a European journal
N2  - Fifteen N-butylpyridinium salts - five monometallic [C4Py](2)[MBr4] and ten bimetallic [C4Py](2)[(M0.5M0.5Br4)-M-a-Br-b] (M=Co, Cu, Mn, Ni, Zn) - were synthesized, and their structures and thermal and electrochemical properties were studied. All the compounds are ionic liquids (ILs) with melting points between 64 and 101 degrees C. Powder and single-crystal X-ray diffraction show that all ILs are isostructural. The electrochemical stability windows of the ILs are between 2 and 3 V. The conductivities at room temperature are between 10(-5) and 10(-6) S cm(-1). At elevated temperatures, the conductivities reach up to 10(-4) S cm(-1) at 70 degrees C. The structures and properties of the current bromide-based ILs were also compared with those of previous examples using chloride ligands, which illustrated differences and similarities between the two groups of ILs.
KW  - electrochemistry
KW  - ionic liquids
KW  - metal-containing ionic liquids;
KW  - N-butylpyridinium bromide
KW  - tetrahalidometallates
Y1  - 2022
U6  - https://doi.org/10.1002/chem.202201068
SN  - 1521-3765
VL  - 28
IS  - 64
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Goebel, Ronald
A1  - Xie, Zai-Lai
A1  - Neumann, Mike
A1  - Günter, Christina
A1  - Loebbicke, Ruben
A1  - Kubo, Shiori
A1  - Titirici, Maria-Magdalena
A1  - Giordano, Cristina
A1  - Taubert, Andreas
T1  - Synthesis of mesoporous carbon/iron carbide hybrids with unusually high surface areas from the ionic liquid precursor [Bmim][FeCl4]
JF  - CrystEngComm
N2  - Mesoporous carbon/iron carbide hybrid materials with surface areas reaching 800 m(2) g(-1) were synthesized via an exotemplating route using monolithic mesoporous silica as template and the ionic liquid 1-butyl-3-methylimidazolium tetrachloridoferrate(III) [Bmim][FeCl4] as carbon and iron source. After heat treatment (750 degrees C under argon) of the [Bmim][FeCl4] precursor confined within the silica matrix, the silica exotemplate was removed with HF leaving the mesoporous C/Fe3C hybrid behind. The surface areas and the pore sizes depend on the exotemplate and the surface areas a significantly larger than any other surface area reported for C/Fe3C hybrid materials so far. The approach is thus a prototype for the synthesis of high-surface area iron carbide-based hybrid materials with potential application in catalysis.
Y1  - 2012
U6  - https://doi.org/10.1039/c2ce25064k
SN  - 1466-8033
VL  - 14
IS  - 15
SP  - 4946
EP  - 4951
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Hamed Misbah, Mohamed
A1  - Santos, Mercedes
A1  - Quintanilla, Luis
A1  - Günter, Christina
A1  - Alonso, Matilde
A1  - Taubert, Andreas
A1  - Carlos Rodriguez-Cabello, Jose
T1  - Recombinant DNA technology and click chemistry: a powerful combination for generating a hybrid elastin-like-statherin hydrogel to control calcium phosphate mineralization
JF  - Beilstein journal of nanotechnology
N2  - Understanding the mechanisms responsible for generating different phases and morphologies of calcium phosphate by elastin-like recombinamers is supreme for bioengineering of advanced multifunctional materials. The generation of such multifunctional hybrid materials depends on the properties of their counterparts and the way in which they are assembled. The success of this assembly depends on the different approaches used, such as recombinant DNA technology and click chemistry. In the present work, an elastin-like recombinamer bearing lysine amino acids distributed along the recombinamer chain has been cross-linked via Huisgen [2 + 3] cycloaddition. The recombinamer contains the SN(A)15 peptide domains inspired by salivary statherin, a peptide epitope known to specifically bind to and nucleate calcium phosphate. The benefit of using click chemistry is that the hybrid elastin-like-statherin recombinamers cross-link without losing their fibrillar structure. Mineralization of the resulting hybrid elastin-like-statherin recombinamer hydrogels with calcium phosphate is described. Thus, two different hydroxyapatite morphologies (cauliflower- and plate-like) have been formed. Overall, this study shows that crosslinking elastin-like recombinamers leads to interesting matrix materials for the generation of calcium phosphate composites with potential applications as biomaterials.
KW  - calcium phosphate
KW  - elastin-like recombinamers
KW  - hydroxyapatite
KW  - mineralization
KW  - SN(A)15
Y1  - 2017
U6  - https://doi.org/10.3762/bjnano.8.80
SN  - 2190-4286
VL  - 8
SP  - 772
EP  - 783
PB  - Beilstein-Institut zur Förderung der Chemischen Wissenschaften
CY  - Frankfurt, Main
ER  - 
TY  - JOUR
A1  - Löbbicke, Ruben
A1  - Chanana, Munish
A1  - Schlaad, Helmut
A1  - Pilz-Allen, Christine
A1  - Günter, Christina
A1  - Möhwald, Helmuth
A1  - Taubert, Andreas
T1  - Polymer Brush Controlled Bioinspired Calcium Phosphate Mineralization and Bone Cell Growth
JF  - Biomacromolecules : an interdisciplinary journal focused at the interface of polymer science and the biological sciences
N2  - Polymer brushes on thiol-modified gold surfaces were synthesized by using terminal thiol groups for the surface initiated free radical polymerization of methacrylic acid and dimethylaminotheyl methacrylate, respectively. Atomic force microscopy shows that the resulting poly(methacrylic acid (PMAA) and poly(dimethylaminothyl methacrylate) (PDM- AEMA) brushes are homogeneous. Contact angle measurements show that the brushes are pH responsive and can reversibly be protonated and deprotonated. Mineralization of the brushes with calcium phosphate at different pH yields homogeneously mineralized surfaces, and preosteoblastic cells proliferate-on be number of living cells on the mineralized hybrid surface is ca. 3 times (P corresponding nonmineralized brushes.
Y1  - 2011
U6  - https://doi.org/10.1021/bm200991b
SN  - 1525-7797
VL  - 12
IS  - 10
SP  - 3753
EP  - 3760
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - GEN
A1  - Mai, Tobias
A1  - Boye, Susanne
A1  - Yuan, Jiayin
A1  - Völkel, Antje
A1  - Gräwert, Marlies
A1  - Günter, Christina
A1  - Lederer, Albena
A1  - Taubert, Andreas
T1  - Poly(ethylene oxide)-based block copolymers with very high molecular weights for biomimetic calcium phosphate mineralization
N2  - The present article is among the first reports on the effects of poly(ampholyte)s and poly(betaine)s on the biomimetic formation of calcium phosphate. We have synthesized a series of di- and triblock copolymers based on a non-ionic poly(ethylene oxide) block and several charged methacrylate monomers, 2-(trimethylammonium)ethyl methacrylate chloride, 2-((3-cyanopropyl)-dimethylammonium)ethyl methacrylate chloride, 3-sulfopropyl methacrylate potassium salt, and [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide. The resulting copolymers are either positively charged, ampholytic, or betaine block copolymers. All the polymers have very high molecular weights of over 106 g mol−1. All polymers are water-soluble and show a strong effect on the precipitation and dissolution of calcium phosphate. The strongest effects are observed with triblock copolymers based on a large poly(ethylene oxide) middle block (nominal Mn = 100 000 g mol−1). Surprisingly, the data show that there is a need for positive charges in the polymers to exert tight control over mineralization and dissolution, but that the exact position of the charge in the polymer is of minor importance for both calcium phosphate precipitation and dissolution.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 208 
Y1  - 2015
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-85299
ER  - 
TY  - JOUR
A1  - Mai, Tobias
A1  - Boye, Susanne
A1  - Yuan, Jiayin
A1  - Voelkel, Antje
A1  - Graewert, Marlies
A1  - Günter, Christina
A1  - Lederer, Albena
A1  - Taubert, Andreas
T1  - Poly(ethylene oxide)-based block copolymers with very high molecular weights for biomimetic calcium phosphate mineralization
JF  - RSC Advances
N2  - The present article is among the first reports on the effects of poly(ampholyte)s and poly(betaine) s on the biomimetic formation of calcium phosphate. We have synthesized a series of di- and triblock copolymers based on a non-ionic poly(ethylene oxide) block and several charged methacrylate monomers, 2-(trimethylammonium) ethyl methacrylate chloride, 2-((3-cyanopropyl)-dimethylammonium)ethyl methacrylate chloride, 3-sulfopropyl methacrylate potassium salt, and [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl) ammonium hydroxide. The resulting copolymers are either positively charged, ampholytic, or betaine block copolymers. All the polymers have very high molecular weights of over 10(6) g mol(-1). All polymers are water-soluble and show a strong effect on the precipitation and dissolution of calcium phosphate. The strongest effects are observed with triblock copolymers based on a large poly(ethylene oxide) middle block (nominal M-n = 100 000 g mol(-1)). Surprisingly, the data show that there is a need for positive charges in the polymers to exert tight control over mineralization and dissolution, but that the exact position of the charge in the polymer is of minor importance for both calcium phosphate precipitation and dissolution.
Y1  - 2015
U6  - https://doi.org/10.1039/c5ra20035k
SN  - 2046-2069
VL  - 5
IS  - 125
SP  - 103494
EP  - 103505
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Mai, Tobias
A1  - Boye, Susanne
A1  - Yuan, Jiayin
A1  - Völkel, Antje
A1  - Gräwert, Marlies
A1  - Günter, Christina
A1  - Lederer, Albena
A1  - Taubert, Andreas
T1  - Poly(ethylene oxide)-based block copolymers with very high molecular weights for biomimetic calcium phosphate mineralization
JF  - RSC Advances : an international journal to further the chemical sciences
N2  - The present article is among the first reports on the effects of poly(ampholyte)s and poly(betaine)s on the biomimetic formation of calcium phosphate. We have synthesized a series of di- and triblock copolymers based on a non-ionic poly(ethylene oxide) block and several charged methacrylate monomers, 2-(trimethylammonium)ethyl methacrylate chloride, 2-((3-cyanopropyl)-dimethylammonium)ethyl methacrylate chloride, 3-sulfopropyl methacrylate potassium salt, and [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide. The resulting copolymers are either positively charged, ampholytic, or betaine block copolymers. All the polymers have very high molecular weights of over 106 g mol−1. All polymers are water-soluble and show a strong effect on the precipitation and dissolution of calcium phosphate. The strongest effects are observed with triblock copolymers based on a large poly(ethylene oxide) middle block (nominal Mn = 100 000 g mol−1). Surprisingly, the data show that there is a need for positive charges in the polymers to exert tight control over mineralization and dissolution, but that the exact position of the charge in the polymer is of minor importance for both calcium phosphate precipitation and dissolution.
Y1  - 2015
U6  - https://doi.org/10.1039/c5ra20035k
SN  - 2046-2069
IS  - 5
SP  - 103494
EP  - 103505
PB  - RSC Publishing
CY  - London
ER  -