TY  - JOUR
A1  - Middeldorp, Christel M.
A1  - Mahajan, Anubha
A1  - Horikoshi, Momoko
A1  - Robertson, Neil R.
A1  - Beaumont, Robin N.
A1  - Bradfield, Jonathan P.
A1  - Bustamante, Mariona
A1  - Cousminer, Diana L.
A1  - Day, Felix R.
A1  - De Silva, N. Maneka
A1  - Guxens, Monica
A1  - Mook-Kanamori, Dennis O.
A1  - St Pourcain, Beate
A1  - Warrington, Nicole M.
A1  - Adair, Linda S.
A1  - Ahlqvist, Emma
A1  - Ahluwalia, Tarunveer Singh
A1  - Almgren, Peter
A1  - Ang, Wei
A1  - Atalay, Mustafa
A1  - Auvinen, Juha
A1  - Bartels, Meike
A1  - Beckmann, Jacques S.
A1  - Bilbao, Jose Ramon
A1  - Bond, Tom
A1  - Borja, Judith B.
A1  - Cavadino, Alana
A1  - Charoen, Pimphen
A1  - Chen, Zhanghua
A1  - Coin, Lachlan
A1  - Cooper, Cyrus
A1  - Curtin, John A.
A1  - Custovic, Adnan
A1  - Das, Shikta
A1  - Davies, Gareth E.
A1  - Dedoussis, George V.
A1  - Duijts, Liesbeth
A1  - Eastwood, Peter R.
A1  - Eliasen, Anders U.
A1  - Elliott, Paul
A1  - Eriksson, Johan G.
A1  - Estivill, Xavier
A1  - Fadista, Joao
A1  - Fedko, Iryna O.
A1  - Frayling, Timothy M.
A1  - Gaillard, Romy
A1  - Gauderman, W. James
A1  - Geller, Frank
A1  - Gilliland, Frank
A1  - Gilsanz, Vincente
A1  - Granell, Raquel
A1  - Grarup, Niels
A1  - Groop, Leif
A1  - Hadley, Dexter
A1  - Hakonarson, Hakon
A1  - Hansen, Torben
A1  - Hartman, Catharina A.
A1  - Hattersley, Andrew T.
A1  - Hayes, M. Geoffrey
A1  - Hebebrand, Johannes
A1  - Heinrich, Joachim
A1  - Helgeland, Oyvind
A1  - Henders, Anjali K.
A1  - Henderson, John
A1  - Henriksen, Tine B.
A1  - Hirschhorn, Joel N.
A1  - Hivert, Marie-France
A1  - Hocher, Berthold
A1  - Holloway, John W.
A1  - Holt, Patrick
A1  - Hottenga, Jouke-Jan
A1  - Hypponen, Elina
A1  - Iniguez, Carmen
A1  - Johansson, Stefan
A1  - Jugessur, Astanand
A1  - Kahonen, Mika
A1  - Kalkwarf, Heidi J.
A1  - Kaprio, Jaakko
A1  - Karhunen, Ville
A1  - Kemp, John P.
A1  - Kerkhof, Marjan
A1  - Koppelman, Gerard H.
A1  - Korner, Antje
A1  - Kotecha, Sailesh
A1  - Kreiner-Moller, Eskil
A1  - Kulohoma, Benard
A1  - Kumar, Ashish
A1  - Kutalik, Zoltan
A1  - Lahti, Jari
A1  - Lappe, Joan M.
A1  - Larsson, Henrik
A1  - Lehtimaki, Terho
A1  - Lewin, Alexandra M.
A1  - Li, Jin
A1  - Lichtenstein, Paul
A1  - Lindgren, Cecilia M.
A1  - Lindi, Virpi
A1  - Linneberg, Allan
A1  - Liu, Xueping
A1  - Liu, Jun
A1  - Lowe, William L.
A1  - Lundstrom, Sebastian
A1  - Lyytikainen, Leo-Pekka
A1  - Ma, Ronald C. W.
A1  - Mace, Aurelien
A1  - Magi, Reedik
A1  - Magnus, Per
A1  - Mamun, Abdullah A.
A1  - Mannikko, Minna
A1  - Martin, Nicholas G.
A1  - Mbarek, Hamdi
A1  - McCarthy, Nina S.
A1  - Medland, Sarah E.
A1  - Melbye, Mads
A1  - Melen, Erik
A1  - Mohlke, Karen L.
A1  - Monnereau, Claire
A1  - Morgen, Camilla S.
A1  - Morris, Andrew P.
A1  - Murray, Jeffrey C.
A1  - Myhre, Ronny
A1  - Najman, Jackob M.
A1  - Nivard, Michel G.
A1  - Nohr, Ellen A.
A1  - Nolte, Ilja M.
A1  - Ntalla, Ioanna
A1  - Oberfield, Sharon E.
A1  - Oken, Emily
A1  - Oldehinkel, Albertine J.
A1  - Pahkala, Katja
A1  - Palviainen, Teemu
A1  - Panoutsopoulou, Kalliope
A1  - Pedersen, Oluf
A1  - Pennell, Craig E.
A1  - Pershagen, Goran
A1  - Pitkanen, Niina
A1  - Plomin, Robert
A1  - Power, Christine
A1  - Prasad, Rashmi B.
A1  - Prokopenko, Inga
A1  - Pulkkinen, Lea
A1  - Raikkonen, Katri
A1  - Raitakari, Olli T.
A1  - Reynolds, Rebecca M.
A1  - Richmond, Rebecca C.
A1  - Rivadeneira, Fernando
A1  - Rodriguez, Alina
A1  - Rose, Richard J.
A1  - Salem, Rany
A1  - Santa-Marina, Loreto
A1  - Saw, Seang-Mei
A1  - Schnurr, Theresia M.
A1  - Scott, James G.
A1  - Selzam, Saskia
A1  - Shepherd, John A.
A1  - Simpson, Angela
A1  - Skotte, Line
A1  - Sleiman, Patrick M. A.
A1  - Snieder, Harold
A1  - Sorensen, Thorkild I. A.
A1  - Standl, Marie
A1  - Steegers, Eric A. P.
A1  - Strachan, David P.
A1  - Straker, Leon
A1  - Strandberg, Timo
A1  - Taylor, Michelle
A1  - Teo, Yik-Ying
A1  - Thiering, Elisabeth
A1  - Torrent, Maties
A1  - Tyrrell, Jessica
A1  - Uitterlinden, Andre G.
A1  - van Beijsterveldt, Toos
A1  - van der Most, Peter J.
A1  - van Duijn, Cornelia M.
A1  - Viikari, Jorma
A1  - Vilor-Tejedor, Natalia
A1  - Vogelezang, Suzanne
A1  - Vonk, Judith M.
A1  - Vrijkotte, Tanja G. M.
A1  - Vuoksimaa, Eero
A1  - Wang, Carol A.
A1  - Watkins, William J.
A1  - Wichmann, H-Erich
A1  - Willemsen, Gonneke
A1  - Williams, Gail M.
A1  - Wilson, James F.
A1  - Wray, Naomi R.
A1  - Xu, Shujing
A1  - Xu, Cheng-Jian
A1  - Yaghootkar, Hanieh
A1  - Yi, Lu
A1  - Zafarmand, Mohammad Hadi
A1  - Zeggini, Eleftheria
A1  - Zemel, Babette S.
A1  - Hinney, Anke
A1  - Lakka, Timo A.
A1  - Whitehouse, Andrew J. O.
A1  - Sunyer, Jordi
A1  - Widen, Elisabeth E.
A1  - Feenstra, Bjarke
A1  - Sebert, Sylvain
A1  - Jacobsson, Bo
A1  - Njolstad, Pal R.
A1  - Stoltenberg, Camilla
A1  - Smith, George Davey
A1  - Lawlor, Debbie A.
A1  - Paternoster, Lavinia
A1  - Timpson, Nicholas J.
A1  - Ong, Ken K.
A1  - Bisgaard, Hans
A1  - Bonnelykke, Klaus
A1  - Jaddoe, Vincent W. V.
A1  - Tiemeier, Henning
A1  - Jarvelin, Marjo-Riitta
A1  - Evans, David M.
A1  - Perry, John R. B.
A1  - Grant, Struan F. A.
A1  - Boomsma, Dorret I.
A1  - Freathy, Rachel M.
A1  - McCarthy, Mark I.
A1  - Felix, Janine F.
T1  - The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia
BT  - design, results and future prospects
JF  - European journal of epidemiology
N2  - The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.
KW  - Genetics
KW  - Consortium
KW  - Childhood traits and disorders
KW  - Longitudinal
Y1  - 2019
U6  - https://doi.org/10.1007/s10654-019-00502-9
SN  - 0393-2990
SN  - 1573-7284
VL  - 34
IS  - 3
SP  - 279
EP  - 300
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - GEN
A1  - Gamba, Cristina
A1  - Jones, Eppie R.
A1  - Teasdale, Matthew D.
A1  - McLaughlin, Russell L.
A1  - González-Fortes, Gloria M.
A1  - Mattiangeli, Valeria
A1  - Domboróczki, László
A1  - Kővári, Ivett
A1  - Pap, Ildikó
A1  - Anders, Alexandra
A1  - Whittle, Alasdair
A1  - Dani, János
A1  - Raczky, Pál
A1  - Higham, Thomas F. G.
A1  - Hofreiter, Michael
A1  - Bradley, Daniel G.
A1  - Pinhasi, Ron
T1  - Genome flux and stasis in a five millennium transect of European prehistory
T2  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - The Great Hungarian Plain was a crossroads of cultural transformations that have shaped European prehistory. Here we analyse a 5,000-year transect of human genomes, sampled from petrous bones giving consistently excellent endogenous DNA yields, from 13 Hungarian Neolithic, Copper, Bronze and Iron Age burials including two to high (similar to 22x) and seven to similar to 1x coverage, to investigate the impact of these on Europe's genetic landscape. These data suggest genomic shifts with the advent of the Neolithic, Bronze and Iron Ages, with interleaved periods of genome stability. The earliest Neolithic context genome shows a European hunter-gatherer genetic signature and a restricted ancestral population size, suggesting direct contact between cultures after the arrival of the first farmers into Europe. The latest, Iron Age, sample reveals an eastern genomic influence concordant with introduced Steppe burial rites. We observe transition towards lighter pigmentation and surprisingly, no Neolithic presence of lactase persistence.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1332 
KW  - ancient DNA
KW  - lactase-persistence
KW  - positive selection
KW  - patterns
KW  - sequence
KW  - farmers
KW  - pigmentation
KW  - homozygosity
KW  - ancestry
KW  - skin
Y1  - 2014
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-437999
SN  - 1866-8372
VL  - 5
IS  - 1332
ER  - 
TY  - JOUR
A1  - Pinhasi, Ron
A1  - Fernandes, Daniel
A1  - Sirak, Kendra
A1  - Novak, Mario
A1  - Connell, Sarah
A1  - Alpaslan-Roodenberg, Songul
A1  - Gerritsen, Fokke
A1  - Moiseyev, Vyacheslav
A1  - Gromov, Andrey
A1  - Raczky, Pal
A1  - Anders, Alexandra
A1  - Pietrusewsky, Michael
A1  - Rollefson, Gary
A1  - Jovanovic, Marija
A1  - Trinhhoang, Hiep
A1  - Bar-Oz, Guy
A1  - Oxenham, Marc
A1  - Matsumura, Hirofumi
A1  - Hofreiter, Michael
T1  - Optimal Ancient DNA Yields from the Inner Ear Part of the Human Petrous Bone
JF  - PLoS one
N2  - The invention and development of next or second generation sequencing methods has resulted in a dramatic transformation of ancient DNA research and allowed shotgun sequencing of entire genomes from fossil specimens. However, although there are exceptions, most fossil specimens contain only low (similar to 1% or less) percentages of endogenous DNA. The only skeletal element for which a systematically higher endogenous DNA content compared to other skeletal elements has been shown is the petrous part of the temporal bone. In this study we investigate whether (a) different parts of the petrous bone of archaeological human specimens give different percentages of endogenous DNA yields, (b) there are significant differences in average DNA read lengths, damage patterns and total DNA concentration, and (c) it is possible to obtain endogenous ancient DNA from petrous bones from hot environments. We carried out intra-petrous comparisons for ten petrous bones from specimens from Holocene archaeological contexts across Eurasia dated between 10,0001,800 calibrated years before present (cal. BP). We obtained shotgun DNA sequences from three distinct areas within the petrous: a spongy part of trabecular bone (part A), the dense part of cortical bone encircling the osseous inner ear, or otic capsule (part B), and the dense part within the otic capsule (part C). Our results confirm that dense bone parts of the petrous bone can provide high endogenous aDNA yields and indicate that endogenous DNA fractions for part C can exceed those obtained for part B by up to 65-fold and those from part A by up to 177-fold, while total endogenous DNA concentrations are up to 126-fold and 109-fold higher for these comparisons. Our results also show that while endogenous yields from part C were lower than 1% for samples from hot (both arid and humid) parts, the DNA damage patterns indicate that at least some of the reads originate from ancient DNA molecules, potentially enabling ancient DNA analyses of samples from hot regions that are otherwise not amenable to ancient DNA analyses.
Y1  - 2015
U6  - https://doi.org/10.1371/journal.pone.0129102
SN  - 1932-6203
VL  - 10
IS  - 6
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - GEN
A1  - Pinhasi, Ron
A1  - Fernandes, Daniel
A1  - Sirak, Kendra
A1  - Novak, Mario
A1  - Connell, Sarah
A1  - Alpaslan-Roodenberg, Songül
A1  - Gerritsen, Fokke
A1  - Moiseyev, Vyacheslav
A1  - Gromov, Andrey
A1  - Raczky, Pál
A1  - Anders, Alexandra
A1  - Pietrusewsky, Michael
A1  - Rollefson, Gary
A1  - Jovanovic, Marija
A1  - Trinhhoang, Hiep
A1  - Bar-Oz, Guy
A1  - Oxenham, Marc
A1  - Matsumura, Hirofumi
A1  - Hofreiter, Michael
T1  - Optimal ancient DNA yields from the inner ear part of the human petrous bone
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschafliche Reihe
N2  - The invention and development of next or second generation sequencing methods has resulted in a dramatic transformation of ancient DNA research and allowed shotgun sequencing of entire genomes from fossil specimens. However, although there are exceptions, most fossil specimens contain only low (similar to 1% or less) percentages of endogenous DNA. The only skeletal element for which a systematically higher endogenous DNA content compared to other skeletal elements has been shown is the petrous part of the temporal bone. In this study we investigate whether (a) different parts of the petrous bone of archaeological human specimens give different percentages of endogenous DNA yields, (b) there are significant differences in average DNA read lengths, damage patterns and total DNA concentration, and (c) it is possible to obtain endogenous ancient DNA from petrous bones from hot environments. We carried out intra-petrous comparisons for ten petrous bones from specimens from Holocene archaeological contexts across Eurasia dated between 10,0001,800 calibrated years before present (cal. BP). We obtained shotgun DNA sequences from three distinct areas within the petrous: a spongy part of trabecular bone (part A), the dense part of cortical bone encircling the osseous inner ear, or otic capsule (part B), and the dense part within the otic capsule (part C). Our results confirm that dense bone parts of the petrous bone can provide high endogenous aDNA yields and indicate that endogenous DNA fractions for part C can exceed those obtained for part B by up to 65-fold and those from part A by up to 177-fold, while total endogenous DNA concentrations are up to 126-fold and 109-fold higher for these comparisons. Our results also show that while endogenous yields from part C were lower than 1% for samples from hot (both arid and humid) parts, the DNA damage patterns indicate that at least some of the reads originate from ancient DNA molecules, potentially enabling ancient DNA analyses of samples from hot regions that are otherwise not amenable to ancient DNA analyses.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 515 
KW  - genome sequence
KW  - extraction
KW  - patterns
KW  - survival
KW  - damage
Y1  - 2019
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-409557
SN  - 1866-8372
IS  - 515
ER  - 
TY  - JOUR
A1  - Gamba, Cristina
A1  - Jones, Eppie R.
A1  - Teasdale, Matthew D.
A1  - McLaughlin, Russell L.
A1  - González-Fortes, Gloria M.
A1  - Mattiangeli, Valeria
A1  - Domboroczki, Laszlo
A1  - Kovari, Ivett
A1  - Pap, Ildiko
A1  - Anders, Alexandra
A1  - Whittle, Alasdair
A1  - Dani, Janos
A1  - Raczky, Pal
A1  - Higham, Thomas F. G.
A1  - Hofreiter, Michael
A1  - Bradley, Daniel G.
A1  - Pinhasi, Ron
T1  - Genome flux and stasis in a five millennium transect of European prehistory
JF  - Nature Communications
N2  - The Great Hungarian Plain was a crossroads of cultural transformations that have shaped European prehistory. Here we analyse a 5,000-year transect of human genomes, sampled from petrous bones giving consistently excellent endogenous DNA yields, from 13 Hungarian Neolithic, Copper, Bronze and Iron Age burials including two to high (similar to 22x) and seven to similar to 1x coverage, to investigate the impact of these on Europe's genetic landscape. These data suggest genomic shifts with the advent of the Neolithic, Bronze and Iron Ages, with interleaved periods of genome stability. The earliest Neolithic context genome shows a European hunter-gatherer genetic signature and a restricted ancestral population size, suggesting direct contact between cultures after the arrival of the first farmers into Europe. The latest, Iron Age, sample reveals an eastern genomic influence concordant with introduced Steppe burial rites. We observe transition towards lighter pigmentation and surprisingly, no Neolithic presence of lactase persistence.
Y1  - 2014
U6  - https://doi.org/10.1038/ncomms6257
SN  - 2041-1723
VL  - 5
PB  - Nature Publ. Group
CY  - London
ER  - 
TY  - RPRT
A1  - Brodeur, Abel
A1  - Mikola, Derek
A1  - Cook, Nikolai
A1  - Brailey, Thomas
A1  - Briggs, Ryan
A1  - Gendre, Alexandra de
A1  - Dupraz, Yannick
A1  - Fiala, Lenka
A1  - Gabani, Jacopo
A1  - Gauriot, Romain
A1  - Haddad, Joanne
A1  - Lima, Goncalo
A1  - Ankel-Peters, Jörg
A1  - Dreber, Anna
A1  - Campbell, Douglas
A1  - Kattan, Lamis
A1  - Fages, Diego Marino
A1  - Mierisch, Fabian
A1  - Sun, Pu
A1  - Wright, Taylor
A1  - Connolly, Marie
A1  - Hoces de la Guardia, Fernando
A1  - Johannesson, Magnus
A1  - Miguel, Edward
A1  - Vilhuber, Lars
A1  - Abarca, Alejandro
A1  - Acharya, Mahesh
A1  - Adjisse, Sossou Simplice
A1  - Akhtar, Ahwaz
A1  - Lizardi, Eduardo Alberto Ramirez
A1  - Albrecht, Sabina
A1  - Andersen, Synve Nygaard
A1  - Andlib, Zubaria
A1  - Arrora, Falak
A1  - Ash, Thomas
A1  - Bacher, Etienne
A1  - Bachler, Sebastian
A1  - Bacon, Félix
A1  - Bagues, Manuel
A1  - Balogh, Timea
A1  - Batmanov, Alisher
A1  - Barschkett, Mara
A1  - Basdil, B. Kaan
A1  - Dower, Jaromneda
A1  - Castek, Ondrej
A1  - Caviglia-Harris, Jill
A1  - Strand, Gabriella Chauca
A1  - Chen, Shi
A1  - Chzhen, Asya
A1  - Chung, Jong
A1  - Collins, Jason
A1  - Coppock, Alexander
A1  - Cordeau, Hugo
A1  - Couillard, Ben
A1  - Crechet, Jonathan
A1  - Crippa, Lorenzo
A1  - Cui, Jeanne
A1  - Czymara, Christian
A1  - Daarstad, Haley
A1  - Dao, Danh Chi
A1  - Dao, Dong
A1  - Schmandt, Marco David
A1  - Linde, Astrid de
A1  - Melo, Lucas De
A1  - Deer, Lachlan
A1  - Vera, Micole De
A1  - Dimitrova, Velichka
A1  - Dollbaum, Jan Fabian
A1  - Dollbaum, Jan Matti
A1  - Donnelly, Michael
A1  - Huynh, Luu Duc Toan
A1  - Dumbalska, Tsvetomira
A1  - Duncan, Jamie
A1  - Duong, Kiet Tuan
A1  - Duprey, Thibaut
A1  - Dworschak, Christoph
A1  - Ellingsrud, Sigmund
A1  - Elminejad, Ali
A1  - Eissa, Yasmine
A1  - Erhart, Andrea
A1  - Etingin-Frati, Giulian
A1  - Fatemi-Pour, Elaheh
A1  - Federice, Alexa
A1  - Feld, Jan
A1  - Fenig, Guidon
A1  - Firouzjaeiangalougah, Mojtaba
A1  - Fleisje, Erlend
A1  - Fortier-Chouinard, Alexandre
A1  - Engel, Julia Francesca
A1  - Fries, Tilman
A1  - Fortier, Reid
A1  - Fréchet, Nadjim
A1  - Galipeau, Thomas
A1  - Gallegos, Sebastián
A1  - Gangji, Areez
A1  - Gao, Xiaoying
A1  - Garnache, Cloé
A1  - Gáspár, Attila
A1  - Gavrilova, Evelina
A1  - Ghosh, Arijit
A1  - Gibney, Garreth
A1  - Gibson, Grant
A1  - Godager, Geir
A1  - Goff, Leonard
A1  - Gong, Da
A1  - González, Javier
A1  - Gretton, Jeremy
A1  - Griffa, Cristina
A1  - Grigoryeva, Idaliya
A1  - Grtting, Maja
A1  - Guntermann, Eric
A1  - Guo, Jiaqi
A1  - Gugushvili, Alexi
A1  - Habibnia, Hooman
A1  - Häffner, Sonja
A1  - Hall, Jonathan D.
A1  - Hammar, Olle
A1  - Kordt, Amund Hanson
A1  - Hashimoto, Barry
A1  - Hartley, Jonathan S.
A1  - Hausladen, Carina I.
A1  - Havránek, Tomáš
A1  - Hazen, Jacob
A1  - He, Harry
A1  - Hepplewhite, Matthew
A1  - Herrera-Rodriguez, Mario
A1  - Heuer, Felix
A1  - Heyes, Anthony
A1  - Ho, Anson T. Y.
A1  - Holmes, Jonathan
A1  - Holzknecht, Armando
A1  - Hsu, Yu-Hsiang Dexter
A1  - Hu, Shiang-Hung
A1  - Huang, Yu-Shiuan
A1  - Huebener, Mathias
A1  - Huber, Christoph
A1  - Huynh, Kim P.
A1  - Irsova, Zuzana
A1  - Isler, Ozan
A1  - Jakobsson, Niklas
A1  - Frith, Michael James
A1  - Jananji, Raphaël
A1  - Jayalath, Tharaka A.
A1  - Jetter, Michael
A1  - John, Jenny
A1  - Forshaw, Rachel Joy
A1  - Juan, Felipe
A1  - Kadriu, Valon
A1  - Karim, Sunny
A1  - Kelly, Edmund
A1  - Dang, Duy Khanh Hoang
A1  - Khushboo, Tazia
A1  - Kim, Jin
A1  - Kjellsson, Gustav
A1  - Kjelsrud, Anders
A1  - Kotsadam, Andreas
A1  - Korpershoek, Jori
A1  - Krashinsky, Lewis
A1  - Kundu, Suranjana
A1  - Kustov, Alexander
A1  - Lalayev, Nurlan
A1  - Langlois, Audrée
A1  - Laufer, Jill
A1  - Lee-Whiting, Blake
A1  - Leibing, Andreas
A1  - Lenz, Gabriel
A1  - Levin, Joel
A1  - Li, Peng
A1  - Li, Tongzhe
A1  - Lin, Yuchen
A1  - Listo, Ariel
A1  - Liu, Dan
A1  - Lu, Xuewen
A1  - Lukmanova, Elvina
A1  - Luscombe, Alex
A1  - Lusher, Lester R.
A1  - Lyu, Ke
A1  - Ma, Hai
A1  - Mäder, Nicolas
A1  - Makate, Clifton
A1  - Malmberg, Alice
A1  - Maitra, Adit
A1  - Mandas, Marco
A1  - Marcus, Jan
A1  - Margaryan, Shushanik
A1  - Márk, Lili
A1  - Martignano, Andres
A1  - Marsh, Abigail
A1  - Masetto, Isabella
A1  - McCanny, Anthony
A1  - McManus, Emma
A1  - McWay, Ryan
A1  - Metson, Lennard
A1  - Kinge, Jonas Minet
A1  - Mishra, Sumit
A1  - Mohnen, Myra
A1  - Möller, Jakob
A1  - Montambeault, Rosalie
A1  - Montpetit, Sébastien
A1  - Morin, Louis-Philippe
A1  - Morris, Todd
A1  - Moser, Scott
A1  - Motoki, Fabio
A1  - Muehlenbachs, Lucija
A1  - Musulan, Andreea
A1  - Musumeci, Marco
A1  - Nabin, Munirul
A1  - Nchare, Karim
A1  - Neubauer, Florian
A1  - Nguyen, Quan M. P.
A1  - Nguyen, Tuan
A1  - Nguyen-Tien, Viet
A1  - Niazi, Ali
A1  - Nikolaishvili, Giorgi
A1  - Nordstrom, Ardyn
A1  - Nü, Patrick
A1  - Odermatt, Angela
A1  - Olson, Matt
A1  - ien, Henning
A1  - Ölkers, Tim
A1  - Vert, Miquel Oliver i.
A1  - Oral, Emre
A1  - Oswald, Christian
A1  - Ousman, Ali
A1  - Özak, Ömer
A1  - Pandey, Shubham
A1  - Pavlov, Alexandre
A1  - Pelli, Martino
A1  - Penheiro, Romeo
A1  - Park, RyuGyung
A1  - Martel, Eva Pérez
A1  - Petrovičová, Tereza
A1  - Phan, Linh
A1  - Prettyman, Alexa
A1  - Procházka, Jakub
A1  - Putri, Aqila
A1  - Quandt, Julian
A1  - Qiu, Kangyu
A1  - Nguyen, Loan Quynh Thi
A1  - Rahman, Andaleeb
A1  - Rea, Carson H.
A1  - Reiremo, Adam
A1  - Renée, Laëtitia
A1  - Richardson, Joseph
A1  - Rivers, Nicholas
A1  - Rodrigues, Bruno
A1  - Roelofs, William
A1  - Roemer, Tobias
A1  - Rogeberg, Ole
A1  - Rose, Julian
A1  - Roskos-Ewoldsen, Andrew
A1  - Rosmer, Paul
A1  - Sabada, Barbara
A1  - Saberian, Soodeh
A1  - Salamanca, Nicolas
A1  - Sator, Georg
A1  - Sawyer, Antoine
A1  - Scates, Daniel
A1  - Schlüter, Elmar
A1  - Sells, Cameron
A1  - Sen, Sharmi
A1  - Sethi, Ritika
A1  - Shcherbiak, Anna
A1  - Sogaolu, Moyosore
A1  - Soosalu, Matt
A1  - Srensen, Erik
A1  - Sovani, Manali
A1  - Spencer, Noah
A1  - Staubli, Stefan
A1  - Stans, Renske
A1  - Stewart, Anya
A1  - Stips, Felix
A1  - Stockley, Kieran
A1  - Strobel, Stephenson
A1  - Struby, Ethan
A1  - Tang, John
A1  - Tanrisever, Idil
A1  - Yang, Thomas Tao
A1  - Tastan, Ipek
A1  - Tatić, Dejan
A1  - Tatlow, Benjamin
A1  - Seuyong, Féraud Tchuisseu
A1  - Thériault, Rémi
A1  - Thivierge, Vincent
A1  - Tian, Wenjie
A1  - Toma, Filip-Mihai
A1  - Totarelli, Maddalena
A1  - Tran, Van-Anh
A1  - Truong, Hung
A1  - Tsoy, Nikita
A1  - Tuzcuoglu, Kerem
A1  - Ubfal, Diego
A1  - Villalobos, Laura
A1  - Walterskirchen, Julian
A1  - Wang, Joseph Taoyi
A1  - Wattal, Vasudha
A1  - Webb, Matthew D.
A1  - Weber, Bryan
A1  - Weisser, Reinhard
A1  - Weng, Wei-Chien
A1  - Westheide, Christian
A1  - White, Kimberly
A1  - Winter, Jacob
A1  - Wochner, Timo
A1  - Woerman, Matt
A1  - Wong, Jared
A1  - Woodard, Ritchie
A1  - Wroński, Marcin
A1  - Yazbeck, Myra
A1  - Yang, Gustav Chung
A1  - Yap, Luther
A1  - Yassin, Kareman
A1  - Ye, Hao
A1  - Yoon, Jin Young
A1  - Yurris, Chris
A1  - Zahra, Tahreen
A1  - Zaneva, Mirela
A1  - Zayat, Aline
A1  - Zhang, Jonathan
A1  - Zhao, Ziwei
A1  - Yaolang, Zhong
T1  - Mass reproducibility and replicability
BT  - a new hope
T2  - I4R discussion paper series
N2  - This study pushes our understanding of research reliability by reproducing and replicating claims from 110 papers in leading economic and political science journals. The analysis involves computational reproducibility checks and robustness assessments. It reveals several patterns. First, we uncover a high rate of fully computationally reproducible results (over 85%). Second, excluding minor issues like missing packages or broken pathways, we uncover coding errors for about 25% of studies, with some studies containing multiple errors. Third, we test the robustness of the results to 5,511 re-analyses. We find a robustness reproducibility of about 70%. Robustness reproducibility rates are relatively higher for re-analyses that introduce new data and lower for re-analyses that change the sample or the definition of the dependent variable. Fourth, 52% of re-analysis effect size estimates are smaller than the original published estimates and the average statistical significance of a re-analysis is 77% of the original. Lastly, we rely on six teams of researchers working independently to answer eight additional research questions on the determinants of robustness reproducibility. Most teams find a negative relationship between replicators' experience and reproducibility, while finding no relationship between reproducibility and the provision of intermediate or even raw data combined with the necessary cleaning codes.
KW  - conomics
KW  - open science
KW  - political science
KW  - replication
KW  - reproduction
KW  - research transparency
Y1  - 2024
SN  - 2752-1931
IS  - 107
PB  - Institute for Replication
CY  - Essen
ER  -