TY - JOUR A1 - Wiethaus, Jessica A1 - Mueller, Alexandra A1 - Neumann, Meina A1 - Neumann, Sandra A1 - Leimkühler, Silke A1 - Narberhaus, Franz A1 - Masepohl, Bernd T1 - Specific interactions between four Molybdenum-binding proteins contribute to Mo-dependent gene regulation in Rhodobacter capsulatus N2 - The phototrophic purple bacterium Rhodobacter capsulatus encodes two transcriptional regulators, MopA and MopB, with partially overlapping and specific functions in molybdate-dependent gene regulation. Both MopA and MopB consist of an N-terminal DNA-binding helix-turn-helix domain and a C-terminal molybdate-binding di-MOP domain. They formed homodimers as apo-proteins and in the molybdate-bound state as shown by yeast two-hybrid (Y2H) studies, glutaraldehyde cross-linking, gel filtration chromatography, and copurification experiments. Y2H studies suggested that both the DNA- binding and the molybdate-binding domains contribute to dimer formation. Analysis of molybdate binding to MopA and MopB revealed a binding stoichiometry of four molybdate oxyanions per homodimer. Specific interaction partners of MopA and MopB were the molybdate transporter ATPase ModC and the molbindin-like Mop protein, respectively. Like other molbindins, the R. capsulatus Mop protein formed hexamers, which were stabilized by binding of six molybdate oxyanions per hexamer. Heteromer formation of MopA and MopB was shown by Y2H studies and copurification experiments. Reporter gene activity of a strictly MopA-dependent mop-lacZ fusion in mutant strains defective for either mopA, mopB, or both suggested that MopB negatively modulates expression of the mop promoter. We propose that depletion of the active MopA homodimer pool by formation of MopA-MopB heteromers might represent a fine-tuning mechanism controlling mop gene expression. Y1 - 2009 UR - http://jb.asm.org/ U6 - https://doi.org/10.1128/Jb.00526-09 SN - 0021-9193 ER - TY - JOUR A1 - Costard, Sylvia A1 - Stadie, Nicole A1 - Ritter, Christiane A1 - Moll, Kristina A1 - Landerl, Karin A1 - Kohnen, Saskia A1 - Kentner, Gerrit A1 - Bethmann, Anja A1 - Scheich, Henning A1 - Brechmann, André A1 - De Kok, Dörte A1 - Berger, Frauke A1 - Sticher, Heike A1 - Czepluch, Christine A1 - Mätzener, Flurina A1 - Wilmes, Stefanie A1 - Hadert, Sandra A1 - Frank, Ulrike A1 - Mäder, Mark A1 - Westermann, Antje A1 - Meinusch, Miriam A1 - Neumann, Sandra A1 - Düsterhöft, Stefanie A1 - Posse, Dorothea A1 - Puritz, Caroline A1 - Seidl, Rainer Ottis A1 - Etzien, Maria A1 - Machleb, Franziska A1 - Lorenz, Antje A1 - Höger, Maria A1 - Schröder, Astrid A1 - Busch, Tobias A1 - Heide, Judith A1 - Tagoe, Tanja A1 - Watermeyer, Melanie A1 - Höhle, Barbara A1 - Kauschke, Christina ED - Hanne, Sandra ED - Fritzsche, Tom ED - Ott, Susan ED - Adelt, Anne T1 - Spektrum Patholinguistik = Schwerpunktthema: Lesen lernen: Diagnostik und Therapie bei Störungen des Leseerwerbs T1 - Spektrum Patholinguistik = Key issue: Learning to read: Assessment and intervention in developmental reading disorders N2 - Am 20. November 2010 fand an der Universität Potsdam das 4. Herbsttreffen Patholinguistik statt. Die Konferenzreihe wird regelmäßig seit 2007 vom Verband für Patholinguistik e.V. (vpl) durchgeführt. Der vorliegende Tagungsband veröffentlicht die Hauptvorträge des Herbsttreffens zum Thema "Lesen lernen: Diagnostik und Therapie bei Störungen des Leseerwerbs". Des Weiteren sind die Beiträge promovierender bzw. promovierter PatholinguistInnen sowie der Posterpräsentationen enthalten. N2 - On November 20, 2010, the 4th Herbsttreffen Patholinguistik took place at the University of Potsdam. This annual conference is organized by the Verband für Patholinguistik e.V. (vpl). The main topic was "Learning to read: Assessment and intervention in developmental dyslexia". These proceedings contain the four main lectures, the contributed talks of the "Spektrum Patholinguistik" covering various psycho- and neurolinguistic research areas, and the abstracts of the presented posters. T3 - Spektrum Patholinguistik - 4 KW - Patholinguistik KW - Sprachtherapie KW - Leseerwerb KW - Dyslexie KW - Lese-Rechtschreib-Schwäche KW - patholinguistics KW - speech/language therapy KW - reading development KW - reading skills KW - dyslexia Y1 - 2011 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-53146 SN - 978-3-86956-145-5 SN - 1869-3822 SN - 1866-9433 IS - 4 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Neumann, Sandra A1 - Quinting, Jana A1 - Rosenkranz, Anna A1 - De Beer, Carola A1 - Jonas, Kristina A1 - Stenneken, Prisca T1 - Quality of life in adults with neurogenic speech-language-communication difficulties BT - A systematic review of existing measures JF - Journal of communication disorders Y1 - 2019 U6 - https://doi.org/10.1016/j.jcomdis.2019.01.003 SN - 0021-9924 SN - 1873-7994 VL - 79 SP - 24 EP - 45 PB - Elsevier CY - New York ER - TY - JOUR A1 - Tan, Sarah A1 - Düring, Sarah A1 - Wilde, Alina A1 - Hamburger, Lara A1 - Fritzsche, Tom A1 - Felsing, Ulrike A1 - Lauer, Norina A1 - Corsten, Sabine A1 - Ostermann, Frank A1 - Nonn, Kerstin A1 - Nerz, Verena A1 - Neumann, Sandra A1 - Zauke, Svenja A1 - Sandrieser, Patricia A1 - Steinberg, Romy Simone A1 - Thurmann, Anika A1 - Dörr, Fiona A1 - Bilda, Kerstin A1 - Kluth, Alicia A1 - Lemire-Tremblay, Marilyne A1 - Jamey, Kevin A1 - Dalla Bella, Simone A1 - Falk, Simone A1 - Kleingünther, Constanze A1 - Gabler, Katrin A1 - Elligsen, Chiara A1 - Weiland, Katharina A1 - Wiehe, Lea A1 - Wahl, Michael A1 - Binczyk, Sarah A1 - Staebel, Cornelia A1 - Jung, Stefanie A1 - Eikerling, Maren A1 - Czok, Clara A1 - Sallat, Stephan A1 - Collasius, Valerie A1 - Grahovac, Tena ED - Tan, Sarah ED - Düring, Sarah ED - Wilde, Alina ED - Hamburger, Lara ED - Fritzsche, Tom T1 - Spektrum Patholinguistik Band 16. Schwerpunktthema: Schnittstelle Alltag: Transfer und Teilhabe in der Sprachtherapie N2 - Das 16. Herbsttreffen Patholinguistik mit dem Schwerpunktthema »Schnittstelle Alltag: Transfer und Teilhabe in der Sprachtherapie« fand am 19.11.2022 als Online-Veranstaltung statt. Das Herbsttreffen wird seit 2007 jährlich vom Verband für Patholinguistik e.V. (vpl), seit 2021 vom Deutschen Bundesverband für akademische Sprachtherapie und Logopädie (dbs) in Kooperation mit der Universität Potsdam durchgeführt. Der vorliegende Tagungsband beinhaltet die Vorträge zum Schwerpunktthema sowie die Posterpräsentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis. N2 - The Sixteenth Autumn Meeting Patholinguistics with its main topic »Interface everyday life: Transfer and participation in speech/language therapy« took place online on the 19th of November 2022. This annual meeting has been organised since 2007 by the Association for Patholinguistics (vpl), since 2021 by the German Federal Association for Academic Speech/Language Therapy and Logopaedics (dbs) in cooperation with the University of Potsdam. The present proceedings feature the presentations on the main topic as well as articles from the poster session covering a broad range of areas in research and practice of speech/language therapy. T3 - Spektrum Patholinguistik - 16 KW - Patholinguistik KW - Sprachtherapie KW - Transfer KW - Teilhabe KW - patholinguistics KW - speech/language therapy KW - transfer KW - participation Y1 - 2023 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-590433 SN - 978-3-86956-559-0 SN - 1866-9433 SN - 1869-3822 IS - 16 PB - Universitätsverlag Potsdam CY - Potsdam ER -