TY  - GEN
A1  - Javanainen, Matti
A1  - Martinez-Seara, Hector
A1  - Metzler, Ralf
A1  - Vattulainen, Ilpo Tapio
T1  - Diffusion of Proteins and Lipids in Protein-Rich Membranesa
T2  - Biophysical journal
Y1  - 2018
U6  - https://doi.org/10.1016/j.bpj.2017.11.3009
SN  - 0006-3495
SN  - 1542-0086
VL  - 114
IS  - 3
SP  - 551A
EP  - 551A
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Gudowska-Nowak, Ewa
A1  - Lindenberg, Katja
A1  - Metzler, Ralf
T1  - Preface: Marian Smoluchowski’s 1916 paper—a century of inspiration
T2  - Journal of physics : A, Mathematical and theoretical
Y1  - 2017
U6  - https://doi.org/10.1088/1751-8121/aa8529
SN  - 1751-8113
SN  - 1751-8121
VL  - 50
IS  - 38
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - GEN
A1  - Metzler, Ralf
T1  - Gaussianity Fair
BT  - the Riddle of Anomalous yet Non-Gaussian Diffusion
T2  - Biophysical journal
Y1  - 2017
U6  - https://doi.org/10.1016/j.bpj.2016.12.019
SN  - 0006-3495
SN  - 1542-0086
VL  - 112
IS  - 3
SP  - 413
EP  - 415
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Metzler, Ralf
T1  - Anomalous Diffusion in Membranes and the Cytoplasm of Biological Cells
T2  - Biophysical journal
Y1  - 2017
U6  - https://doi.org/10.1016/j.bpj.2016.11.2577
SN  - 0006-3495
SN  - 1542-0086
VL  - 112
IS  - 3
SP  - 476A
EP  - 476A
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Barkai, Eli
A1  - Garini, Yuval
A1  - Metzler, Ralf
T1  - Electrostatic effects in living cells Reply
T2  - PHYSICS TODAY
Y1  - 2013
SN  - 0031-9228
SN  - 1945-0699
VL  - 66
IS  - 7
SP  - 11
EP  - 11
PB  - AMER INST PHYSICS
CY  - MELVILLE
ER  - 
TY  - GEN
A1  - Talukder, Srijeeta
A1  - Sen, Shrabani
A1  - Chakraborti, Prantik
A1  - Metzler, Ralf
A1  - Banik, Suman K.
A1  - Chaudhury, Pinaki
T1  - Breathing dynamics based parameter sensitivity analysis of hetero-polymeric DNA
T2  - The journal of chemical physics : bridges a gap between journals of physics and journals of chemistr
N2  - We study the parameter sensitivity of hetero-polymeric DNA within the purview of DNA breathing dynamics. The degree of correlation between the mean bubble size and the model parameters is estimated for this purpose for three different DNA sequences. The analysis leads us to a better understanding of the sequence dependent nature of the breathing dynamics of hetero-polymeric DNA. Out of the 14 model parameters for DNA stability in the statistical Poland-Scheraga approach, the hydrogen bond interaction epsilon(hb)(AT) for an AT base pair and the ring factor. turn out to be the most sensitive parameters. In addition, the stacking interaction epsilon(st)(TA-TA) for an TA-TA nearest neighbor pair of base-pairs is found to be the most sensitive one among all stacking interactions. Moreover, we also establish that the nature of stacking interaction has a deciding effect on the DNA breathing dynamics, not the number of times a particular stacking interaction appears in a sequence. We show that the sensitivity analysis can be used as an effective measure to guide a stochastic optimization technique to find the kinetic rate constants related to the dynamics as opposed to the case where the rate constants are measured using the conventional unbiased way of optimization.
Y1  - 2014
U6  - https://doi.org/10.1063/1.4871297
SN  - 0021-9606
SN  - 1089-7690
VL  - 140
IS  - 14
PB  - American Institute of Physics
CY  - Melville
ER  - 
TY  - GEN
A1  - Metzler, Ralf
T1  - PROTEIN PHYSICS Forever ageing
T2  - Nature physics
N2  - Single-molecule techniques have long given us insight into the motion and interactions of individual molecules. But simulations now show that the dynamics inside single proteins is not as simple as we thought — and that proteins are forever changing.
Y1  - 2016
U6  - https://doi.org/10.1038/nphys3585
SN  - 1745-2473
SN  - 1745-2481
VL  - 12
SP  - 113
EP  - 114
PB  - Nature Publ. Group
CY  - London
ER  -