TY - JOUR A1 - Lehmann, Andreas A1 - Eccard, Jana A1 - Scheffler, Christiane A1 - Kurvers, Ralf H. J. M. A1 - Dammhahn, Melanie T1 - Under pressure: human adolescents express a pace-of-life syndrome JF - Behavioral ecology and sociobiology N2 - The pace-of-life syndrome (POLS) hypothesis posits that life-history characteristics, among individual differences in behavior, and physiological traits have coevolved in response to environmental conditions. This hypothesis has generated much research interest because it provides testable predictions concerning the association between the slow-fast life-history continuum and behavioral and physiological traits. Although humans are among the most well-studied species and similar concepts exist in the human literature, the POLS hypothesis has not yet been directly applied to humans. Therefore, we aimed to (i) test predicted relationships between life history, physiology, and behavior in a human population and (ii) better integrate the POLS hypothesis with other similar concepts. Using data of a representative sample of German adolescents, we extracted maturation status for girls (menarche, n = 791) and boys (voice break, n = 486), and a set of health-related risk-taking behaviors and cardiovascular parameters. Maturation status and health-related risk behavior as well as maturation status and cardiovascular physiology covaried in boys and girls. Fast maturing boys and girls had higher blood pressure and expressed more risk-taking behavior than same-aged slow maturing boys and girls, supporting general predictions of the POLS hypothesis. Only some physiological and behavioral traits were positively correlated, suggesting that behavioral and physiological traits might mediate life-history trade-offs differently. Moreover, some aspects of POLS were sex-specific. Overall, the POLS hypothesis shares many similarities with other conceptual frameworks from the human literature and these concepts should be united more thoroughly to stimulate the study of POLS in humans and other animals. Significance statement The pace-of-life syndrome (POLS) hypothesis suggests that life history, behavioral and physiological traits have coevolved in response to environmental conditions. Here, we tested this link in a representative sample of German adolescents, using data from a large health survey (the KIGGs study) containing information on individual age and state of maturity for girls and boys, and a set of health-related risk-taking behaviors and cardiovascular parameters. We found that fast maturing girls and boys had overall higher blood pressure and expressed more risk-taking behavior than same-aged slow maturing girls and boys. Only some behavioral and physiological traits were positively correlated, suggesting that behavioral and physiological traits might mediate life-history trade-offs differently and not necessarily form a syndrome. Our results demonstrate a general link between life history, physiological and behavioral traits in humans, while simultaneously highlighting a more complex and rich set of relationships, since not all relationships followed predictions by the POLS hypothesis. KW - Adolescence KW - Humans KW - Life history KW - Menarche KW - Physiology KW - Risk taking Y1 - 2018 U6 - https://doi.org/10.1007/s00265-018-2465-y SN - 0340-5443 SN - 1432-0762 VL - 72 IS - 3 PB - Springer CY - New York ER - TY - GEN A1 - Hermanussen, Michael A1 - Ipsen, Josefin A1 - Mumm, Rebekka A1 - Assmann, Christian A1 - Quitmann, Julia A1 - Gomula, Aleksandra A1 - Lehmann, Andreas A1 - Jasch, Isabelle A1 - Tassenaar, Vincent A1 - Bogin, Barry A1 - Satake, Takashi A1 - Scheffler, Christiane A1 - Nunez, Javier A1 - Godina, Elena A1 - Hardeland, Ruediger A1 - Boldsen, Jesper L. A1 - El-Shabrawi, Mortada A1 - Elhusseini, Mona A1 - Barbu, Carmen Gabriela A1 - Pop, Ralucca A1 - Soederhaell, Jani A1 - Merker, Andrea A1 - Swanson, James A1 - Groth, Detlef T1 - Stunted Growth. Proceedings of the 23rd Aschauer Soiree, Held at Aschauhof, Germany, November 7th 2015 T2 - Pediatric Endocrinology Reviews N2 - Twenty-four scientists met at Aschauhof, Altenhof, Germany, to discuss the associations between child growth and development, and nutrition, health, environment and psychology. Meta-analyses of body height, height variability and household inequality, in historic and modern growth studies published since 1794, highlighting the enormously flexible patterns of child and adolescent height and weight increments throughout history which do not only depend on genetics, prenatal development, nutrition, health, and economic circumstances, but reflect social interactions. A Quality of Life in Short Stature Youth Questionnaire was presented to cross-culturally assess health-related quality of life in children. Changes of child body proportions in recent history, the relation between height and longevity in historic Dutch samples and also measures of body height in skeletal remains belonged to the topics of this meeting. Bayesian approaches and Monte Carlo simulations offer new statistical tools for the study of human growth. KW - Adolescent growth KW - Peer group KW - Growth hormone KW - Community effect KW - Body height Y1 - 2016 SN - 1565-4753 VL - 13 SP - 756 EP - 767 PB - Medical Media CY - Netanya ER - TY - CHAP A1 - Lehmann, Andreas A1 - Tryggvadottir, Laufey A1 - Scheffler, Christiane A1 - Hermanussen, Michael T1 - Menarcheal age and body height in Iceland in the last century T2 - Journal of biological and clinical anthropology : Anthropologischer Anzeiger ; Mitteilungsorgan der Gesellschaft für Anthropologie Y1 - 2011 SN - 0003-5548 VL - 68 IS - 4 SP - 507 EP - 508 PB - Schweizerbart CY - Stuttgart ER - TY - JOUR A1 - Hermanussen, Michael A1 - Lehmann, Andreas A1 - Scheffler, Christiane T1 - Sexuelle Reifeentwicklung & Menarchealter : Bedeutung des psychosozialen Umfeldes damals und heute Y1 - 2012 SN - 0179-9185 ER - TY - THES A1 - Lehmann, Andreas T1 - Variability in human life history traits BT - an analysis of spatial and temporal variation and their integration into recent conceptual frameworks Y1 - 2018 ER - TY - JOUR A1 - Hermanussen, Michael A1 - Lehmann, Andreas A1 - Scheffler, Christiane T1 - Psychosocial Pressure and Menarche A Review of Historic Evidence for Social Amenorrhea JF - Obstetrical & gynecological survey N2 - Objective: The age of menarche is usually considered to be affected by nutritional, health-related, social, and economic factors and has significantly decreased since the mid-19th century. The present study was performed to investigate whether the timing of menarche paralleled the general acceleration of physical development, or whether this pattern differed. Study Design: In all, 30 German studies on menarcheal age (n = > 200) since 1848 were collected. Frequency distributions were analyzed. Results: During the second half of the 19th and the early 20th century, mean menarcheal age decreased from 18 to 12-13 years in Europe. Yet, the data fail to support the conventional hypothesis that menarcheal age mainly depends on nutritional, health, and economic factors. Conclusions: We suggest that later than usual menarche may not necessarily be regarded as a physical illness, but in view of the apparently physiological delay of menarche in the 19th century, may be viewed as "collective social amenorrhea." Target Audience: Obstetricians & Gynecologists and Family Physicians. Learning Objectives: After participating in this CME activity, physicians should be better able to evaluate menarche as an indicator of developmental tempo in both historical and modern settings, compare menarche in healthy mid-19th century girls with menarche in average modern girls, and assess the marked sensitivity of full pubertal development to environmental circumstances. Y1 - 2012 U6 - https://doi.org/10.1097/OGX.0b013e31824c94ad SN - 0029-7828 VL - 67 IS - 4 SP - 237 EP - 241 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Kroke, Anja A1 - Schmidt, Annemarie A1 - Amini, Anna M. A1 - Kalotai, Nicole A1 - Lehmann, Andreas A1 - Haardt, Julia A1 - Bauer, Jürgen M. A1 - Bischoff-Ferrari, Heike A. A1 - Boeing, Heiner A1 - Egert, Sarah A1 - Ellinger, Sabine A1 - Kühn, Tilman A1 - Louis, Sandrine A1 - Lorkowski, Stefan A1 - Nimptsch, Katharina A1 - Remer, Thomas A1 - Schulze, Matthias B. A1 - Siener, Roswitha A1 - Stangl, Gabriele A1 - Volkert, Dorothee A1 - Zittermann, Armin A1 - Buyken, Anette E. A1 - Watzl, Bernhard A1 - Schwingshackl, Lukas T1 - Dietary protein intake and health-related outcomes: a methodological protocol for the evidence evaluation and the outline of an evidence to decision framework underlying the evidence-based guideline of the German Nutrition Society JF - European journal of nutrition N2 - Purpose: The present work aimed to delineate (i) a revised protocol according to recent methodological developments in evidence generation, to (ii) describe its interpretation, the assessment of the overall certainty of evidence and to (iii) outline an Evidence to Decision framework for deriving an evidence-based guideline on quantitative and qualitative aspects of dietary protein intake. Methods A methodological protocol to systematically investigate the association between dietary protein intake and several health outcomes and for deriving dietary protein intake recommendations for the primary prevention of various non-communicable diseases in the general adult population was developed. Results The developed methodological protocol relies on umbrella reviews including systematic reviews with or without meta-analyses. Systematic literature searches in three databases will be performed for each health-related outcome. The methodological quality of all selected systematic reviews will be evaluated using a modified version of AMSTAR 2, and the outcome-specific certainty of evidence for systematic reviews with or without meta-analysis will be assessed with NutriGrade. The general outline of the Evidence to Decision framework foresees that recommendations in the derived guideline will be given based on the overall certainty of evidence as well as on additional criteria such as sustainability. Conclusion The methodological protocol permits a systematic evaluation of published systematic reviews on dietary protein intake and its association with selected health-related outcomes. An Evidence to Decision framework will be the basis for the overall conclusions and the resulting recommendations for dietary protein intake. KW - Evidence-based guideline KW - Protein intake KW - Method KW - Prevention KW - Nutrition-related diseases Y1 - 2022 U6 - https://doi.org/10.1007/s00394-021-02789-5 SN - 1436-6207 SN - 1436-6215 VL - 61 IS - 4 SP - 2091 EP - 2101 PB - Springer Nature CY - Heidelberg ER -