TY - JOUR A1 - Marin-Beloqui, Jose A1 - Zhang, Guanran A1 - Guo, Junjun A1 - Shaikh, Jordan A1 - Wohrer, Thibaut A1 - Hosseini, Seyed Mehrdad A1 - Sun, Bowen A1 - Shipp, James A1 - Auty, Alexander J. A1 - Chekulaev, Dimitri A1 - Ye, Jun A1 - Chin, Yi-Chun A1 - Sullivan, Michael B. A1 - Mozer, Attila J. A1 - Kim, Ji-Seon A1 - Shoaee, Safa A1 - Clarke, Tracey M. T1 - Insight into the origin of trapping in polymer/fullerene blends with a systematic alteration of the fullerene to higher adducts JF - Journal of physical chemistry C N2 - The bimolecular recombination characteristics of conjugated polymer poly[(4,4'-bis(2-ethylhexyl)dithieno[3,2-b:2',3'-d]silole)-2,6-diyl-alt-(2,5-bis 3-tetradecylthiophen-2-y1 thiazolo 5,4-d thiazole)-2,5diy1] (PDTSiTTz) blended with the fullerene series PC60BM, ICMA, ICBA, and ICTA have been investigated using microsecond and femtosecond transient absorption spectroscopy, in conjunction with electroluminescence measurements and ambient photoemission spectroscopy. The non-Langevin polymer PDTSiTTz allows an inspection of intrinsic bimolecular recombination rates uninhibited by diffusion, while the low oscillator strengths of fullerenes allow polymer features to dominate, and we compare our results to those of the well-known polymer Si-PCPDTBT. Using mu s-TAS, we have shown that the trap -limited decay dynamics of the PDTSiTTz polaron becomes progressively slower across the fullerene series, while those of Si-PCPDTBT are invariant. Electroluminescence measurements showed an unusual double peak in pristine PDTSiTTz, attributed to a low energy intragap charge transfer state, likely interchain in nature. Furthermore, while the pristine PDTSiTTz showed a broad, low-intensity density of states, the ICBA and ICTA blends presented a virtually identical DOS to Si-PCPDTBT and its blends. This has been attributed to a shift from a delocalized, interchain highest occupied molecular orbital (HOMO) in the pristine material to a dithienosilole-centered HOMO in the blends, likely a result of the bulky fullerenes increasing interchain separation. This HOMO localization had a side effect of progressively shifting the polymer HOMO to shallower energies, which was correlated with the observed decrease in bimolecular recombination rate and increased "trap" depth. However, since the density of tail states remained the same, this suggests that the traditional viewpoint of "trapping" being dominated by tail states may not encompass the full picture and that the breadth of the DOS may also have a strong influence on bimolecular recombination. Y1 - 2022 U6 - https://doi.org/10.1021/acs.jpcc.1c10378 SN - 1932-7447 SN - 1932-7455 VL - 126 IS - 5 SP - 2708 EP - 2719 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Flóvenz, Ólafur G. A1 - Wang, Rongjiang A1 - Hersir, Gylfi Páll A1 - Dahm, Torsten A1 - Hainzl, Sebastian A1 - Vassileva, Magdalena A1 - Drouin, Vincent A1 - Heimann, Sebastian A1 - Isken, Marius Paul A1 - Gudnason, Egill Á. A1 - Ágústsson, Kristján A1 - Ágústsdóttir, Thorbjörg A1 - Horálek, Josef A1 - Motagh, Mahdi A1 - Walter, Thomas R. A1 - Rivalta, Eleonora A1 - Jousset, Philippe A1 - Krawczyk, Charlotte M. A1 - Milkereit, Claus T1 - Cyclical geothermal unrest as a precursor to Iceland's 2021 Fagradalsfjall eruption JF - Nature geoscience N2 - Understanding and constraining the source of geodetic deformation in volcanic areas is an important component of hazard assessment. Here, we analyse deformation and seismicity for one year before the March 2021 Fagradalsfjall eruption in Iceland. We generate a high-resolution catalogue of 39,500 earthquakes using optical cable recordings and develop a poroelastic model to describe three pre-eruptional uplift and subsidence cycles at the Svartsengi geothermal field, 8 km west of the eruption site. We find the observed deformation is best explained by cyclic intrusions into a permeable aquifer by a fluid injected at 4 km depth below the geothermal field, with a total volume of 0.11 ± 0.05 km3 and a density of 850 ± 350 kg m–3. We therefore suggest that ingression of magmatic CO2 can explain the geodetic, gravity and seismic data, although some contribution of magma cannot be excluded. Y1 - 2022 U6 - https://doi.org/10.1038/s41561-022-00930-5 SN - 1752-0894 SN - 1752-0908 VL - 15 IS - 5 SP - 397 EP - 404 PB - Nature Research CY - Berlin ER - TY - JOUR A1 - Kaya, Mustafa Yücel A1 - Dupont-Nivet, Guillaume A1 - Frieling, Joost A1 - Fioroni, Chiara A1 - Rohrmann, Alexander A1 - Altıner, Sevinç Özkan A1 - Vardar, Ezgi A1 - Tanyas, Hakan A1 - Mamtimin, Mehmut A1 - Zhaojie, Guo T1 - The Eurasian epicontinental sea was an important carbon sink during the Palaeocene-Eocene thermal maximum JF - Communications earth and environment N2 - The Palaeocene-Eocene Thermal Maximum (ca. 56 million years ago) offers a primary analogue for future global warming and carbon cycle recovery. Yet, where and how massive carbon emissions were mitigated during this climate warming event remains largely unknown. Here we show that organic carbon burial in the vast epicontinental seaways that extended over Eurasia provided a major carbon sink during the Palaeocene-Eocene Thermal Maximum. We coupled new and existing stratigraphic analyses to a detailed paleogeographic framework and using spatiotemporal interpolation calculated ca. 720–1300 Gt organic carbon excess burial, focused in the eastern parts of the Eurasian epicontinental seaways. A much larger amount (2160–3900 Gt C, and when accounting for the increase in inundated shelf area 7400–10300 Gt C) could have been sequestered in similar environments globally. With the disappearance of most epicontinental seas since the Oligocene-Miocene, an effective negative carbon cycle feedback also disappeared making the modern carbon cycle critically dependent on the slower silicate weathering feedback. Y1 - 2022 U6 - https://doi.org/10.1038/s43247-022-00451-4 SN - 2662-4435 VL - 3 IS - 1 PB - Springer Nature CY - London ER - TY - JOUR A1 - Klose, Tim A1 - Guillemoteau, Julien A1 - Vignoli, Giulio A1 - Walter, Judith A1 - Herrmann, Andreas A1 - Tronicke, Jens T1 - Structurally constrained inversion by means of a Minimum Gradient Support regularizer BT - examples of FD-EMI data inversion constrained by GPR reflection data JF - Geophysical journal international N2 - Many geophysical inverse problems are known to be ill-posed and, thus, requiring some kind of regularization in order to provide a unique and stable solution. A possible approach to overcome the inversion ill-posedness consists in constraining the position of the model interfaces. For a grid-based parameterization, such a structurally constrained inversion can be implemented by adopting the usual smooth regularization scheme in which the local weight of the regularization is reduced where an interface is expected. By doing so, sharp contrasts are promoted at interface locations while standard smoothness constraints keep affecting the other regions of the model. In this work, we present a structurally constrained approach and test it on the inversion of frequency-domain electromagnetic induction (FD-EMI) data using a regularization approach based on the Minimum Gradient Support stabilizer, which is capable to promote sharp transitions everywhere in the model, i.e., also in areas where no structural a prioriinformation is available. Using 1D and 2D synthetic data examples, we compare the proposed approach to a structurally constrained smooth inversion as well as to more standard (i.e., not structurally constrained) smooth and sharp inversions. Our results demonstrate that the proposed approach helps in finding a better and more reliable reconstruction of the subsurface electrical conductivity distribution, including its structural characteristics. Furthermore, we demonstrate that it allows to promote sharp parameter variations in areas where no structural information are available. Lastly, we apply our structurally constrained scheme to FD-EMI field data collected at a field site in Eastern Germany to image the thickness of peat deposits along two selected profiles. In this field example, we use collocated constant offset ground-penetrating radar (GPR) data to derive structural a priori information to constrain the inversion of the FD-EMI data. The results of this case study demonstrate the effectiveness and flexibility of the proposed approach. KW - Controlled source electromagnetics (CSEM) KW - Inverse theory KW - Electrical properties KW - Ground penetrating radar KW - Frequency Domain Electromagnetics KW - Inversion Y1 - 2023 U6 - https://doi.org/10.1093/gji/ggad041 SN - 0956-540X SN - 1365-246X VL - 233 IS - 3 SP - 1938 EP - 1949 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Córdoba, Sandra Correa A1 - Tong, Hao A1 - Burgos, Asdrubal A1 - Zhu, Feng A1 - Alseekh, Saleh A1 - Fernie, Alisdair R. A1 - Nikoloski, Zoran T1 - Identification of gene function based on models capturing natural variability of Arabidopsis thaliana lipid metabolism JF - Nature Communications N2 - The use of automated tools to reconstruct lipid metabolic pathways is not warranted in plants. Here, the authors construct Plant Lipid Module for Arabidopsis rosette using constraint-based modeling, demonstrate its integration in other plant metabolic models, and use it to dissect the genetic architecture of lipid metabolism. Lipids play fundamental roles in regulating agronomically important traits. Advances in plant lipid metabolism have until recently largely been based on reductionist approaches, although modulation of its components can have system-wide effects. However, existing models of plant lipid metabolism provide lumped representations, hindering detailed study of component modulation. Here, we present the Plant Lipid Module (PLM) which provides a mechanistic description of lipid metabolism in the Arabidopsis thaliana rosette. We demonstrate that the PLM can be readily integrated in models of A. thaliana Col-0 metabolism, yielding accurate predictions (83%) of single lethal knock-outs and 75% concordance between measured transcript and predicted flux changes under extended darkness. Genome-wide associations with fluxes obtained by integrating the PLM in diel condition- and accession-specific models identify up to 65 candidate genes modulating A. thaliana lipid metabolism. Using mutant lines, we validate up to 40% of the candidates, paving the way for identification of metabolic gene function based on models capturing natural variability in metabolism. KW - Biochemical networks KW - Biochemical reaction networks KW - Genetic models KW - Plant molecular biology Y1 - 2023 U6 - https://doi.org/10.1038/s41467-023-40644-9 SN - 2041-1723 VL - 14 IS - 1 PB - Springer Nature CY - London ER - TY - JOUR A1 - Cesca, Simone A1 - Sugan, Monica A1 - Rudzinski, Lukasz A1 - Vajedian, Sanaz A1 - Niemz, Peter A1 - Plank, Simon A1 - Petersen, Gesa A1 - Deng, Zhiguo A1 - Rivalta, Eleonora A1 - Vuan, Alessandro A1 - Linares, Milton Percy Plasencia A1 - Heimann, Sebastian A1 - Dahm, Torsten T1 - Massive earthquake swarm driven by magmatic intrusion at the Bransfield Strait, Antarctica JF - Communications earth and environment N2 - An earthquake swarm affected the Bransfield Strait, Antarctica, a unique rift basin in transition from intra-arc rifting to ocean spreading. The swarm, counting similar to 85,000 volcano-tectonic earthquakes since August 2020, is located close to the Orca submarine volcano, previously considered inactive. Simultaneously, geodetic data reported up to similar to 11 cm north-westward displacement over King George Island. We use a broad variety of geophysical data and methods to reveal the complex migration of seismicity, accompanying the intrusion of 0.26-0.56 km(3) of magma. Strike-slip earthquakes mark the intrusion at depth, while shallower normal faulting the similar to 20 km long lateral growth of a dike. Seismicity abruptly decreased after a Mw 6.0 earthquake, suggesting the magmatic dike lost pressure with the slipping of a large fault. A seafloor eruption is likely, but not confirmed by sea surface temperature anomalies. The unrest documents episodic magmatic intrusion in the Bransfield Strait, providing unique insights into active continental rifting. Y1 - 2022 U6 - https://doi.org/10.1038/s43247-022-00418-5 SN - 2662-4435 VL - 3 IS - 1 PB - Springer Nature CY - London ER - TY - JOUR A1 - Bouamra, Marwa A1 - Zouhal, Hassane A1 - Ratel, Sébastien A1 - Makhlouf, Issam A1 - Bezrati, Ikram A1 - Chtara, Mokhtar A1 - Behm, David G. A1 - Granacher, Urs A1 - Chaouachi, Anis T1 - Concurrent training promotes greater gains on body composition and components of physical fitness than single-mode training (endurance or resistance) in youth with obesity JF - Frontiers in physiology N2 - The prevalence of obesity in the pediatric population has become a major public health issue. Indeed, the dramatic increase of this epidemic causes multiple and harmful consequences, Physical activity, particularly physical exercise, remains to be the cornerstone of interventions against childhood obesity. Given the conflicting findings with reference to the relevant literature addressing the effects of exercise on adiposity and physical fitness outcomes in obese children and adolescents, the effect of duration-matched concurrent training (CT) [50% resistance (RT) and 50% high-intensity-interval-training (HIIT)] on body composition and physical fitness in obese youth remains to be elucidated. Thus, the purpose of this study was to examine the effects of 9-weeks of CT compared to RT or HIIT alone, on body composition and selected physical fitness components in healthy sedentary obese youth. Out of 73 participants, only 37; [14 males and 23 females; age 13.4 +/- 0.9 years; body-mass-index (BMI): 31.2 +/- 4.8 kg center dot m-2] were eligible and randomized into three groups: HIIT (n = 12): 3-4 setsx12 runs at 80-110% peak velocity, with 10-s passive recovery between bouts; RT (n = 12): 6 exercises; 3-4 sets x 10 repetition maximum (RM) and CT (n = 13): 50% serial completion of RT and HIIT. CT promoted significant greater gains compared to HIIT and RT on body composition (p < 0.01, d = large), 6-min-walking test distance (6 MWT-distance) and on 6 MWT-VO2max (p < 0.03, d = large). In addition, CT showed substantially greater improvements than HIIT in the medicine ball throw test (20.2 vs. 13.6%, p < 0.04, d = large). On the other hand, RT exhibited significantly greater gains in relative hand grip strength (p < 0.03, d = large) and CMJ (p < 0.01, d = large) than HIIT and CT. CT promoted greater benefits for fat, body mass loss and cardiorespiratory fitness than HIIT or RT modalities. This study provides important information for practitioners and therapists on the application of effective exercise regimes with obese youth to induce significant and beneficial body composition changes. The applied CT program and the respective programming parameters in terms of exercise intensity and volume can be used by practitioners as an effective exercise treatment to fight the pandemic overweight and obesity in youth. KW - weight loss KW - adolescents KW - high-intensity-interval training KW - resistance KW - training KW - DXA KW - matched time Y1 - 2022 U6 - https://doi.org/10.3389/fphys.2022.869063 SN - 1664-042X VL - 13 PB - Frontiers Media CY - Lausanne ER - TY - JOUR A1 - Cheng, Feng A1 - Dennis, Alice B. A1 - Osuoha, Josephine Ijeoma A1 - Canitz, Julia A1 - Kirschbaum, Frank A1 - Tiedemann, Ralph T1 - A new genome assembly of an African weakly electric fish (Campylomormyrus compressirostris, Mormyridae) indicates rapid gene family evolution in Osteoglossomorpha JF - BMC genomics N2 - Background Teleost fishes comprise more than half of the vertebrate species. Within teleosts, most phylogenies consider the split between Osteoglossomorpha and Euteleosteomorpha/Otomorpha as basal, preceded only by the derivation of the most primitive group of teleosts, the Elopomorpha. While Osteoglossomorpha are generally species poor, the taxon contains the African weakly electric fish (Mormyroidei), which have radiated into numerous species. Within the mormyrids, the genus Campylomormyrus is mostly endemic to the Congo Basin. Campylomormyrus serves as a model to understand mechanisms of adaptive radiation and ecological speciation, especially with regard to its highly diverse species-specific electric organ discharges (EOD). Currently, there are few well-annotated genomes available for electric fish in general and mormyrids in particular. Our study aims at producing a high-quality genome assembly and to use this to examine genome evolution in relation to other teleosts. This will facilitate further understanding of the evolution of the osteoglossomorpha fish in general and of electric fish in particular. Results A high-quality weakly electric fish (C. compressirostris) genome was produced from a single individual with a genome size of 862 Mb, consisting of 1,497 contigs with an N50 of 1,399 kb and a GC-content of 43.69%. Gene predictions identified 34,492 protein-coding genes, which is a higher number than in the two other available Osteoglossomorpha genomes of Paramormyrops kingsleyae and Scleropages formosus. A Computational Analysis of gene Family Evolution (CAFE5) comparing 33 teleost fish genomes suggests an overall faster gene family turnover rate in Osteoglossomorpha than in Otomorpha and Euteleosteomorpha. Moreover, the ratios of expanded/contracted gene family numbers in Osteoglossomorpha are significantly higher than in the other two taxa, except for species that had undergone an additional genome duplication (Cyprinus carpio and Oncorhynchus mykiss). As potassium channel proteins are hypothesized to play a key role in EOD diversity among species, we put a special focus on them, and manually curated 16 Kv1 genes. We identified a tandem duplication in the KCNA7a gene in the genome of C. compressirostris. Conclusions We present the fourth genome of an electric fish and the third well-annotated genome for Osteoglossomorpha, enabling us to compare gene family evolution among major teleost lineages. Osteoglossomorpha appear to exhibit rapid gene family evolution, with more gene family expansions than contractions. The curated Kv1 gene family showed seven gene clusters, which is more than in other analyzed fish genomes outside Osteoglossomorpha. The KCNA7a, encoding for a potassium channel central for EOD production and modulation, is tandemly duplicated which may related to the diverse EOD observed among Campylomormyrus species. KW - Campylomormyrus KW - Pacbio sequencing KW - Gene family KW - Osteoglossomorpha KW - Kv1 Y1 - 2023 U6 - https://doi.org/10.1186/s12864-023-09196-6 SN - 1471-2164 VL - 24 IS - 1 PB - BMC CY - London ER - TY - JOUR A1 - Rosin, Paul L. A1 - Lai, Yu-Kun A1 - Mould, David A1 - Yi, Ran A1 - Berger, Itamar A1 - Doyle, Lars A1 - Lee, Seungyong A1 - Li, Chuan A1 - Liu, Yong-Jin A1 - Semmo, Amir A1 - Shamir, Ariel A1 - Son, Minjung A1 - Winnemöller, Holger T1 - NPRportrait 1.0: A three-level benchmark for non-photorealistic rendering of portraits JF - Computational visual media N2 - Recently, there has been an upsurge of activity in image-based non-photorealistic rendering (NPR), and in particular portrait image stylisation, due to the advent of neural style transfer (NST). However, the state of performance evaluation in this field is poor, especially compared to the norms in the computer vision and machine learning communities. Unfortunately, the task of evaluating image stylisation is thus far not well defined, since it involves subjective, perceptual, and aesthetic aspects. To make progress towards a solution, this paper proposes a new structured, three-level, benchmark dataset for the evaluation of stylised portrait images. Rigorous criteria were used for its construction, and its consistency was validated by user studies. Moreover, a new methodology has been developed for evaluating portrait stylisation algorithms, which makes use of the different benchmark levels as well as annotations provided by user studies regarding the characteristics of the faces. We perform evaluation for a wide variety of image stylisation methods (both portrait-specific and general purpose, and also both traditional NPR approaches and NST) using the new benchmark dataset. KW - non-photorealistic rendering (NPR) KW - image stylization KW - style transfer KW - portrait KW - evaluation KW - benchmark Y1 - 2022 U6 - https://doi.org/10.1007/s41095-021-0255-3 SN - 2096-0433 SN - 2096-0662 VL - 8 IS - 3 SP - 445 EP - 465 PB - Springer Nature CY - London ER - TY - JOUR A1 - Irrgang, Anna M. A1 - Bendixen, Mette A1 - Farquharson, Louise M. A1 - Baranskaya, Alisa A1 - Erikson, Li H. A1 - Gibbs, Ann E. A1 - Ogorodov, Stanislav A. A1 - Overduin, Pier Paul A1 - Lantuit, Hugues A1 - Grigoriev, Mikhail N. A1 - Jones, Benjamin M. T1 - Drivers, dynamics and impacts of changing Arctic coasts JF - Nature reviews earth and environment N2 - Arctic coasts are vulnerable to the effects of climate change, including rising sea levels and the loss of permafrost, sea ice and glaciers. Assessing the influence of anthropogenic warming on Arctic coastal dynamics, however, is challenged by the limited availability of observational, oceanographic and environmental data. Yet, with the majority of permafrost coasts being erosive, coupled with projected intensification of erosion and flooding, understanding these changes is critical. In this Review, we describe the morphological diversity of Arctic coasts, discuss important drivers of coastal change, explain the specific sensitivity of Arctic coasts to climate change and provide an overview of pan-Arctic shoreline change and its multifaceted impacts. Arctic coastal changes impact the human environment by threatening coastal settlements, infrastructure, cultural sites and archaeological remains. Changing sediment fluxes also impact the natural environment through carbon, nutrient and pollutant release on a magnitude that remains difficult to predict. Increasing transdisciplinary and interdisciplinary collaboration efforts will build the foundation for identifying sustainable solutions and adaptation strategies to reduce future risks for those living on, working at and visiting the rapidly changing Arctic coast. Y1 - 2022 U6 - https://doi.org/10.1038/s43017-021-00232-1 SN - 2662-138X VL - 3 IS - 1 SP - 39 EP - 54 PB - Nature Research CY - London ER - TY - JOUR A1 - Izotov, Yuri I. A1 - Chisholm, John A1 - Worseck, Gábor A1 - Guseva, Natalia G. A1 - Schaerer, Daniel A1 - Prochaska, Jason Xavier T1 - Lyman alpha and Lyman continuum emission of Mg II-selected star-forming galaxies JF - Monthly notices of the Royal Astronomical Society N2 - We present observations with the Cosmic Origins Spectrograph onboard the Hubble Space Telescope of seven compact low-mass star-forming galaxies at redshifts, z, in the range 0.3161-0.4276, with various O3Mg2 = [O III] lambda 5007/Mg II lambda 2796+2803 and Mg-2 = Mg II lambda 2796/Mg II lambda 2803 emission-line ratios. We aim to study the dependence of leaking Lyman continuum (LyC) emission on the characteristics of Mg ii emission together with the dependencies on other indirect indicators of escaping ionizing radiation. LyC emission with escape fractions f(esc)(LyC) = 3.1-4.6 per cent is detected in four galaxies, whereas only 1 sigma upper limits of f(esc)(LyC) in the remaining three galaxies were derived. A strong narrow Ly alpha emission line with two peaks separated by V-sep similar to 298-592 km s(-1) was observed in four galaxies with detected LyC emission and very weak Ly alpha emission is observed in galaxies with LyC non-detections. Our new data confirm the tight anticorrelation between f(esc)(LyC) and V-sep found for previous low-redshift galaxy samples. V-sep remains the best indirect indicator of LyC leakage among all considered indicators. It is found that escaping LyC emission is detected predominantly in galaxies with Mg-2 greater than or similar to 1.3. A tendency of an increase of f(esc)(LyC) with increasing of both the O3Mg2 and Mg-2 is possibly present. However, there is substantial scatter in these relations not allowing their use for reliable prediction of f(esc)(LyC). KW - galaxies: abundances KW - galaxies: dwarf KW - galaxies: fundamental parameters KW - galaxies: ISM KW - galaxies: starburst KW - dark ages KW - reionization KW - first stars Y1 - 2022 U6 - https://doi.org/10.1093/mnras/stac1899 SN - 0035-8711 SN - 1365-2966 VL - 515 IS - 2 SP - 2864 EP - 2881 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Bereswill, Sarah A1 - Gatz-Miller, Hannah A1 - Su, Danyang A1 - Tötzke, Christian A1 - Kardjilov, Nikolay A1 - Oswald, Sascha E. A1 - Mayer, Klaus Ulrich T1 - Coupling non-invasive imaging and reactive transport modeling to investigate water and oxygen dynamics in the root zone JF - Vadose zone journal N2 - Oxygen (O-2) availability in soils is vital for plant growth and productivity. The transport and consumption of O-2 in the root zone is closely linked to soil moisture content, the spatial distribution of roots, as well as structure and heterogeneity of the surrounding soil. In this study, we measure three-dimensional root system architecture and the spatiotemporal dynamics of soil moisture (& theta;) and O-2 concentrations in the root zone of maize (Zea mays) via non-invasive imaging, and then construct and parameterize a reactive transport model based on the experimental data. The combination of three non-invasive imaging methods allowed for a direct comparison of simulation results with observations at high spatial and temporal resolution. In three different modeling scenarios, we investigated how the results obtained for different levels of conceptual complexity in the model were able to match measured & theta; and O-2 concentration patterns. We found that the modeling scenario that considers heterogeneous soil structure and spatial variability of hydraulic parameters (permeability, porosity, and van Genuchten & alpha; and n), better reproduced the measured & theta; and O-2 patterns relative to a simple model with a homogenous soil domain. The results from our combined imaging and modeling analysis reveal that experimental O-2 and water dynamics can be reproduced quantitatively in a reactive transport model, and that O-2 and water dynamics are best characterized when conditions unique to the specific system beyond the distribution of roots, such as soil structure and its effect on water saturation and macroscopic gas transport pathways, are considered. Y1 - 2023 U6 - https://doi.org/10.1002/vzj2.20268 SN - 1539-1663 VL - 22 IS - 5 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Vitagliano, Gerardo A1 - Hameed, Mazhar A1 - Jiang, Lan A1 - Reisener, Lucas A1 - Wu, Eugene A1 - Naumann, Felix T1 - Pollock: A Data Loading Benchmark JF - Proceedings of the VLDB Endowment N2 - Any system at play in a data-driven project has a fundamental requirement: the ability to load data. The de-facto standard format to distribute and consume raw data is CSV. Yet, the plain text and flexible nature of this format make such files often difficult to parse and correctly load their content, requiring cumbersome data preparation steps. We propose a benchmark to assess the robustness of systems in loading data from non-standard CSV formats and with structural inconsistencies. First, we formalize a model to describe the issues that affect real-world files and use it to derive a systematic lpollutionz process to generate dialects for any given grammar. Our benchmark leverages the pollution framework for the csv format. To guide pollution, we have surveyed thousands of real-world, publicly available csv files, recording the problems we encountered. We demonstrate the applicability of our benchmark by testing and scoring 16 different systems: popular csv parsing frameworks, relational database tools, spreadsheet systems, and a data visualization tool. Y1 - 2023 U6 - https://doi.org/10.14778/3594512.3594518 SN - 2150-8097 VL - 16 IS - 8 SP - 1870 EP - 1882 PB - Association for Computing Machinery CY - New York ER - TY - JOUR A1 - Borýsek, Martin T1 - In search of Ovidian hebrew BT - a philological study of a lesser known modern hebrew translation of Ovid’s Metamorphoses JF - Acta Universitatis Carolinae : AUC N2 - This paper focuses on the first substantial translation of Ovid’s Metamorphoses into modern Hebrew, whose author was Yehoshua Friedman (1885–1934). The first part of the paper sets Friedman into the context of modern Hebrew classical philology and explores the character of his verse. The core of the text consists of three case studies of selected excerpts from Ovid’s story of Apollo and Daphne (Met. I, 456–465; 481–482; 545–552). Based on detailed linguistic and stylistic analysis of these texts, I argue that Friedman did not simply adopt a pre-existing linguistic register, but rather created an original Ovidian idiom that helped to win him lasting significance in the history of Hebrew translations from classical languages. KW - Ovid’s Metamorphoses KW - Yehoshua Friedman KW - modern Hebrew literature KW - classical translations KW - Apollo and Daphne Y1 - 2022 UR - https://karolinum.cz/casopis/auc-philologica/rocnik-2021/cislo-4/clanek-10183 U6 - https://doi.org/10.14712/24646830.2022.11 SN - 0567-8269 SN - 2464-6830 IS - 4 SP - 29 EP - 56 PB - Karolinum Press CY - Prag ER - TY - JOUR A1 - Zakrzewski, Tanja T1 - Miguel de Luna as arbitrista BT - Dossier em Honra à Professora Filomena Barros JF - Hamsa : journal of Judaic and Islamic studies : revista de estudos judaicos e islâmicos N2 - This article deals with Miguel de Luna, a Morisco from Granada, who is most famous for his involvement in the Lead Books of Sacromonte affair. In the following pages I will, however, focus on a facet of his life that has been rather neglected. Rather than recount again his activities as translator for Arabic, I will shed light on his work as physician and claim that his medical paper on the benefits of bathing and the reopening of public baths in Granada may very well put him in league with the arbitristas, a group of intellectuals who advised the monarch in economic and financial matters. KW - Arbitrista KW - Granada KW - history of medicine KW - Morisco KW - Muslim Y1 - 2023 UR - https://journals.openedition.org/hamsa/4231 U6 - https://doi.org/10.4000/hamsa.4231 SN - 2183-2633 IS - 9 SP - 1 EP - 13 PB - Universidade de Évora CY - Évora ER - TY - JOUR A1 - Liberatoscioli, Davide T1 - The new testament and the qur'an as depicted in Abraham Silveira's ‘Telling’ Mute book JF - European Judaism : a journal for the new Europe N2 - Interfaith controversies and disputes regarding the role of reason in interpreting the Scriptures characterised scholarly discussion in the Low Countries between the seventeenth and eighteenth centuries. The Jewish author Abraham Gómez Silveira contributed to this discussion with an eclectic body of literature. This article focuses on his Libro Mudo (Mute Book), which embodies his efforts to present the Jewish religion as the only rational one and the Christian dogma as irrational. In order to corroborate his reading, Silveira mostly bases his argumentation on non-Jewish texts. By selecting passages from the New Testaments, Christian religious commentaries as well as Qur'anic excerpts, Silveira aims to demonstrate that even non-Jewish sources prove the rationality of the Jewish theological system. The novelty of Silveira's approach consists in confuting Christian dogma by accepting the Gospels as reliable historical sources. In this argumentative structure, the Qur'an has a similar although not identical function. KW - Bible criticism KW - Libro Mudo KW - polemics KW - Qur'anic reception KW - Qur'anic translations KW - Abraham Gómez Silveira Y1 - 2023 UR - https://www.berghahnjournals.com/view/journals/european-judaism/56/2/ej560206.xml U6 - https://doi.org/10.3167/ej.2023.560206 SN - 0014-3006 SN - 1752-2323 VL - 56 IS - 2 SP - 47 EP - 61 PB - Berghahn CY - Oxford ER - TY - JOUR A1 - Brinkmann, Kai Oliver A1 - Becker, Tim A1 - Zimmermann, Florian A1 - Kreusel, Cedric A1 - Gahlmann, Tobias A1 - Theisen, Manuel A1 - Haeger, Tobias A1 - Olthof, Selina A1 - Tückmantel, Christian A1 - Günster, M. A1 - Maschwitz, Timo A1 - Göbelsmann, Fabian A1 - Koch, Christine A1 - Hertel, Dirk A1 - Caprioglio, Pietro A1 - Peña-Camargo, Francisco A1 - Perdigón-Toro, Lorena A1 - Al-Ashouri, Amran A1 - Merten, Lena A1 - Hinderhofer, Alexander A1 - Gomell, Leonie A1 - Zhang, Siyuan A1 - Schreiber, Frank A1 - Albrecht, Steve A1 - Meerholz, Klaus A1 - Neher, Dieter A1 - Stolterfoht, Martin A1 - Riedl, Thomas T1 - Perovskite-organic tandem solar cells with indium oxide interconnect JF - Nature N2 - Multijunction solar cells can overcome the fundamental efficiency limits of single-junction devices. The bandgap tunability of metal halide perovskite solar cells renders them attractive for multijunction architectures(1). Combinations with silicon and copper indium gallium selenide (CIGS), as well as all-perovskite tandem cells, have been reported(2-5). Meanwhile, narrow-gap non-fullerene acceptors have unlocked skyrocketing efficiencies for organic solar cells(6,7). Organic and perovskite semiconductors are an attractive combination, sharing similar processing technologies. Currently, perovskite-organic tandems show subpar efficiencies and are limited by the low open-circuit voltage (V-oc) of wide-gap perovskite cells(8) and losses introduced by the interconnect between the subcells(9,10). Here we demonstrate perovskite-organic tandem cells with an efficiency of 24.0 per cent (certified 23.1 per cent) and a high V-oc of 2.15 volts. Optimized charge extraction layers afford perovskite subcells with an outstanding combination of high V-oc and fill factor. The organic subcells provide a high external quantum efficiency in the near-infrared and, in contrast to paradigmatic concerns about limited photostability of non-fullerene cells(11), show an outstanding operational stability if excitons are predominantly generated on the non-fullerene acceptor, which is the case in our tandems. The subcells are connected by an ultrathin (approximately 1.5 nanometres) metal-like indium oxide layer with unprecedented low optical/electrical losses. This work sets a milestone for perovskite-organic tandems, which outperform the best p-i-n perovskite single junctions(12) and are on a par with perovskite-CIGS and all-perovskite multijunctions(13). Y1 - 2022 U6 - https://doi.org/10.1038/s41586-022-04455-0 SN - 0028-0836 SN - 1476-4687 VL - 604 IS - 7905 SP - 280 EP - 286 PB - Nature Research CY - Berlin ER - TY - JOUR A1 - Zapata-Arteaga, Osnat A1 - Marina, Sara A1 - Zuo, Guangzheng A1 - Xu, Kai A1 - Dörling, Bernhard A1 - Alberto Pérez, Luis A1 - Sebastián Reparaz, Juan A1 - Martín, Jaime A1 - Kemerink, Martijn A1 - Campoy-Quiles, Mariano T1 - Design rules for polymer blends with high thermoelectric performance JF - Advanced energy materials N2 - A combinatorial study of the effect of in-mixing of various guests on the thermoelectric properties of the host workhorse polymer poly[2,5-bis(3-tetradecylthiophen-2-yl)thieno[3,2-b]thiophene] (PBTTT) is presented. Specifically, the composition and thickness for doped films of PBTTT blended with different polymers are varied. Some blends at guest weight fractions around 10-15% exhibit up to a fivefold increase in power factor compared to the reference material, leading to zT values around 0.1. Spectroscopic analysis of the charge-transfer species, structural characterization using grazing-incidence wide-angle X-ray scattering, differential scanning calorimetry, Raman, and atomic force microscopy, and Monte Carlo simulations are employed to determine that the key to improved performance is for the guest to promote long-range electrical connectivity and low disorder, together with similar highest occupied molecular orbital levels for both materials in order to ensure electronic connectivity are combined. KW - doping KW - microstructure KW - organic thermoelectrics KW - orientation KW - ternary Y1 - 2022 U6 - https://doi.org/10.1002/aenm.202104076 SN - 1614-6832 SN - 1614-6840 VL - 12 IS - 19 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Niederhofer, Florian A1 - Cioni, Maria-Rosa L. A1 - Schmidt, Thomas A1 - Bekki, Kenji A1 - de Grijs, Richard A1 - Ivanov, Valentin D. A1 - Oliveira, Joana M. A1 - Ripepi, Vincenzo A1 - Subramanian, Smitha A1 - van Loon, Jacco Th T1 - The VMC survey – XLVI. Stellar proper motions in the centre of the Large Magellanic Cloud JF - Monthly notices of the Royal Astronomical Society N2 - We present proper motion (PM) measurements within the central region of the Large Magellanic Cloud (LMC), using near-infrared data from the VISTA survey of the Magellanic Cloud system (VMC). This work encompasses 18 VMC tiles covering a total sky area of similar to 28 deg(2). We computed absolute stellar PMs from multiepoch observations in the K-s filter over time baselines between similar to 12 and 47 months. Our final catalogue contains similar to 6322 000 likely LMC member stars with derived PMs. We employed a simple flat-rotating disc model to analyse and interpret the PM data. We found a stellar centre of rotation (alpha(0) = 79.95 degrees(+0.22)(-0.23), delta(0) = -69.31 degrees(+0.12)(-0.11)) that is in agreement with that resulting from Hubble Space Telescope data. The inferred viewing angles of the LMC disc (i = 33.5 degrees(+1.2)(-1.3), Theta = 129.8 degrees(+1.9)(-1.9)) are in good agreement with values from the literature but suggest a higher inclination of the central parts of the LMC. Our data confirm a higher rotation amplitude for the young (less than or similar to 0.5 Gyr) stars compared to the intermediate-age/old (greater than or similar to 1 Gyr) population, which can be explained by asymmetric drift. We constructed spatially resolved velocity maps of the intermediate-age/old and young populations. Intermediate-age/old stars follow elongated orbits parallel to the bar's major axis, providing first observational evidence for x(1) orbits within the LMC bar. In the innermost regions, the motions show more chaotic structures. Young stars show motions along a central filamentary bar structure. KW - surveys KW - proper motion KW - stars: kinematics and dynamics KW - galaxies: individual: LMC KW - Magellanic Clouds Y1 - 2022 U6 - https://doi.org/10.1093/mnras/stac712 SN - 0035-8711 SN - 1365-2966 VL - 512 IS - 4 SP - 5423 EP - 5439 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Peter, Lena A1 - Wendering, Désirée Jacqueline A1 - Schlickeiser, Stephan A1 - Hoffmann, Henrike A1 - Noster, Rebecca A1 - Wagner, Dimitrios Laurin A1 - Zarrinrad, Ghazaleh A1 - Münch, Sandra A1 - Picht, Samira A1 - Schulenberg, Sarah A1 - Moradian, Hanieh A1 - Mashreghi, Mir-Farzin A1 - Klein, Oliver A1 - Gossen, Manfred A1 - Roch, Toralf A1 - Babel, Nina A1 - Reinke, Petra A1 - Volk, Hans-Dieter A1 - Amini, Leila A1 - Schmueck-Henneresse, Michael T1 - Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients JF - Molecular therapy methods and clinical development N2 - Solid organ transplant (SOT) recipients receive therapeutic immunosuppression that compromises their immune response to infections and vaccines. For this reason, SOT patients have a high risk of developing severe coronavirus disease 2019 (COVID-19) and an increased risk of death from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Moreover, the efficiency of immunotherapies and vaccines is reduced due to the constant immunosuppression in this patient group. Here, we propose adoptive transfer of SARS-CoV-2-specific T cells made resistant to a common immunosuppressant, tacrolimus, for optimized performance in the immunosuppressed patient. Using a ribonucleoprotein approach of CRISPR-Cas9 technology, we have generated tacrolimus-resistant SARS-CoV-2-specific T cell products from convalescent donors and demonstrate their specificity and function through characterizations at the single-cell level, including flow cytometry, single-cell RNA (scRNA) Cellular Indexing of Transcriptomes and Epitopes (CITE), and T cell receptor (TCR) sequencing analyses. Based on the promising results, we aim for clinical validation of this approach in transplant recipients. Additionally, we propose a combinatory approach with tacrolimus, to prevent an overshooting immune response manifested as bystander T cell activation in the setting of severe COVID-19 immunopathology, and tacrolimus-resistant SARS-CoV-2-specific T cell products, allowing for efficient clearance of viral infection. Our strategy has the potential to prevent severe COVID-19 courses in SOT or autoimmunity settings and to prevent immunopathology while providing viral clearance in severe non-transplant COVID-19 cases. Y1 - 2022 U6 - https://doi.org/10.1016/j.omtm.2022.02.012 SN - 2329-0501 VL - 25 SP - 52 EP - 73 PB - Cell Press CY - Cambridge ER -