TY  - JOUR
A1  - Ghods, Mojtaba
A1  - Georgiou, Iakovos
A1  - Schmidt, Jeremias
A1  - Kruppa, Philipp
T1  - Disease progression and comorbidities in lipedema patients
BT  - a 10-year retrospective analysis
JF  - Dermatologic therapy
N2  - Multiple associated comorbidities have been described for lipedema patients. Disease diagnosis still remains challenging in many cases and is frequently delayed. The purpose of this study was to determine the most common comorbidities in lipedema patients and the impact of surgical treatment onto disease progression. A retrospective assessment of disease-related epidemiologic data was performed for patients who underwent liposuction between July 2009 and July 2019 in a specialized clinic for lipedema surgery. All patients received a standardized questionnaire regarding the clinical history and changes of lipedema-associated symptoms and comorbidities after surgery. 106 patients who underwent a total of 298 liposuction procedures were included in this study after returning the questionnaire fully filled-in. Multiple comorbidities were observed in the assessed collective. The prevalence for obesity, hypothyroidism, migraine, and depression were markedly increased in relation to comparable nonlipedema populations. Despite a median body mass index (BMI) of 31.6 kg/m(2) (IQR 26.4-38.8), unexpected low prevalence of diabetes (5%) and dyslipidemia (7%) was found. Diagnosis and initiation of guideline-appropriate treatment were delayed by years in many patients. After surgical treatment (medium follow-up 20 months, IQR 11-42), a significant reduction of lipedema-associated symptoms was demonstrated. Lipedema occurs with a diversity of associated comorbidities. Therefore, on the basis of available data, the authors suggest the necessity of a multimodal therapy concept for a comprehensive and holistic treatment. Despite a commonly increased BMI, lipedema patients appear to have an advantageous metabolic risk profile.
KW  - comorbidities
KW  - epidemiology
KW  - lipedema
KW  - lipoedema
KW  - subcutaneous adipose tissue
Y1  - 2020
U6  - https://doi.org/10.1111/dth.14534
SN  - 1529-8019
VL  - 33
IS  - 6
PB  - Wiley-Blackwell
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Graefen, Johanna
A1  - Kohn, Juliane
A1  - Wyschkon, Anne
A1  - Esser, Günter
T1  - Internalizing problems in children and adolescents with math disability
JF  - Zeitschrift für Psychologie = Journal of psychology
N2  - Research has shown that learning disabilities are associated with internalizing problems in (pre) adolescents. In order to examine this relationship for math disability (MD), math achievement and internalizing problem scores were measured in a representative group of 1,436 (pre) adolescents. MD was defined by a discrepancy between math achievement and IQ. Internalizing problems were measured through a multi-informant (parents, teachers, self-report) approach. The results revealed that MD puts (pre) adolescents at a higher risk for internalizing problems. External and self-ratings differed between boys and girls, indicating that either they show distinct internalizing symptoms or they are being perceived differently by parents and teachers. Results emphasize the importance of both a multi-informant approach and the consideration of gender differences when measuring internalizing symptomatology of children with MD. For an optimal treatment of MD, depressive and anxious symptoms need to be considered.
KW  - math disability
KW  - internalizing problems
KW  - comorbidities
KW  - adolescence
Y1  - 2015
U6  - https://doi.org/10.1027/2151-2604/a000207
SN  - 2190-8370
SN  - 2151-2604
VL  - 223
IS  - 2
SP  - 93
EP  - 101
PB  - Hogrefe
CY  - Göttingen
ER  -