TY  - JOUR
A1  - Qiu, Liang
A1  - Zhang, Haoran
A1  - Bick, Thomas
A1  - Martin, Johannes
A1  - Wendler, Petra
A1  - Böker, Alexander
A1  - Glebe, Ulrich
A1  - Xing, Chengfen
T1  - Construction of highly ordered glyco-inside nano-assemblies through RAFT dispersion polymerization of galactose-decorated monomer
JF  - Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker ; International edition
N2  - Glyco-assemblies derived from amphiphilic sugar-decorated block copolymers (ASBCs) have emerged prominently due to their wide application, for example, in biomedicine and as drug carriers. However, to efficiently construct these glyco-assemblies is still a challenge. Herein, we report an efficient technology for the synthesis of glyco-inside nano-assemblies by utilizing RAFT polymerization of a galactose-decorated methacrylate for polymerization-induced self-assembly (PISA). Using this approach, a series of highly ordered glyco-inside nano-assemblies containing intermediate morphologies were fabricated by adjusting the length of the hydrophobic glycoblock and the polymerization solids content. A specific morphology of complex vesicles was captured during the PISA process and the formation mechanism is explained by the morphology of its precursor and intermediate. Thus, this method establishes a powerful route to fabricate glyco-assemblies with tunable morphologies and variable sizes, which is significant to enable the large-scale fabrication and wide application of glyco-assemblies.
KW  - galactose-decorated monomer
KW  - glyco-inside nano-assemblies
KW  - morphology
KW  - evolution
KW  - PISA
KW  - RAFT dispersion polymerization
Y1  - 2021
U6  - https://doi.org/10.1002/anie.202015692
SN  - 1433-7851
SN  - 1521-3773
VL  - 60
IS  - 20
SP  - 11098
EP  - 11103
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Lenkeit, Jenny
A1  - Schwippert, Knut
A1  - Knigge, Michel
T1  - Configurations of multiple disparities in reading performance
BT  - longitudinal observations across France, Germany, Sweden and the United Kingdom
JF  - Assessment in education : principles, policy & practice
N2  - Research provides evidence that gender, immigrant background and socio-economic characteristics present multiple disadvantaging characteristics that change their relative importance and configurations over time. When evaluating inequalities researchers tend to focus on one particular aspect and often use composite measures when evaluating socio-economic characteristics. Neither can fully represent the complexity of students’ various disadvantaging characteristics, which have autonomous associations with attainment and with each other. This paper investigates how the relative importance and configurations of different disadvantaging factors have changed over time to form educational inequalities and how these changes differ across countries. Data from five PISA cycles (2000–2012) for France, Germany, Sweden and the United Kingdom are used and configurations of gender, immigration background, parents’ occupational and educational levels, and the number of books at home evaluated. Results enable us to relate changes (or lack thereof) in configurations of disadvantaging factors to recent reforms targeted at reducing educational inequality after the first PISA results.
KW  - Educational inequalities
KW  - PISA
KW  - multilevel linear regression
Y1  - 2017
U6  - https://doi.org/10.1080/0969594X.2017.1309352
SN  - 0969-594X
SN  - 1465-329X
VL  - 25
IS  - 1
SP  - 52
EP  - 86
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  -