TY - JOUR A1 - Kühne, Franziska A1 - Meinders, C. A1 - Mohr, H. A1 - Hafenbrack, K. A1 - Kieseritzky, K. A1 - Rosenberger, C. A1 - Haerter, M. A1 - Schulz-Kindermann, F. A1 - Klinger, R. A1 - Nestoriuc, A. Y. T1 - Psychological treatments for pain in cancer patients. A systematic review on the current state of research JF - Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der Österreichischen Schmerzgesellschaft und der Deutschen Interdisziplinären Vereinigung für Schmerztherapie N2 - In cancer patients, pain is one of the main symptoms and especially in the late stages of disease, these symptoms can be associated with considerable suffering. In psycho-oncology, preliminary psychological therapies targeting cancer pain have been tested; however, a systematic review of available interventions is lacking, especially considering their dissemination, evidence base, study quality, and the comparison with established treatments. Therefore, the aim of the current study is to systematically review the current research on psychological treatments for pain in cancer patients. During May 2014, MEDLINE, PsycINFO, PSYNDEX, and CENTRAL databases were searched. Psychological treatments for pain in adult cancer patients studied in randomized, controlled trials (RCTs) and referring to pain as primary or secondary outcome were included. After examination for inclusion, structured data extraction and assessment followed. Data were synthesized narratively. In the review, 32 RCTs were included. Studies mainly referred to patients with breast cancer or patients in earlier stages of the disease. The methodological quality of included studies was heterogeneous. Most commonly, short interventions were delivered by nurses in out-patient settings. Interventions including education and relaxation techniques were utilized most often, followed by interventions with behavioral or cognitive components. A need for research persists regarding efficacy of current psychotherapeutic interventions, or the role of mediator variables (e. g., coping) on pain perception in cancer patients. Studies with high methodological quality which comprehensively and transparently report on interventions and designs are lacking. KW - Neoplasms, psychology KW - Education, patients KW - Relaxation KW - Behavior therapy KW - Cognitive therapy Y1 - 2016 U6 - https://doi.org/10.1007/s00482-016-0169-7 SN - 0932-433X SN - 1432-2129 VL - 30 SP - 496 EP - 509 PB - Springer CY - New York ER - TY - JOUR A1 - Nickerson, David A1 - Atalag, Koray A1 - de Bono, Bernard A1 - Geiger, Joerg A1 - Goble, Carole A1 - Hollmann, Susanne A1 - Lonien, Joachim A1 - Mueller, Wolfgang A1 - Regierer, Babette A1 - Stanford, Natalie J. A1 - Golebiewski, Martin A1 - Hunter, Peter T1 - The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable JF - Interface focus N2 - Reconstructing and understanding the Human Physiome virtually is a complex mathematical problem, and a highly demanding computational challenge. Mathematical models spanning from the molecular level through to whole populations of individuals must be integrated, then personalized. This requires interoperability with multiple disparate and geographically separated data sources, and myriad computational software tools. Extracting and producing knowledge from such sources, even when the databases and software are readily available, is a challenging task. Despite the difficulties, researchers must frequently perform these tasks so that available knowledge can be continually integrated into the common framework required to realize the Human Physiome. Software and infrastructures that support the communities that generate these, together with their underlying standards to format, describe and interlink the corresponding data and computer models, are pivotal to the Human Physiome being realized. They provide the foundations for integrating, exchanging and re-using data and models efficiently, and correctly, while also supporting the dissemination of growing knowledge in these forms. In this paper, we explore the standards, software tooling, repositories and infrastructures that support this work, and detail what makes them vital to realizing the Human Physiome. KW - Human Physiome KW - standards KW - repositories KW - service infrastructure KW - reproducible science KW - managing big data Y1 - 2016 U6 - https://doi.org/10.1098/rsfs.2015.0103 SN - 2042-8898 SN - 2042-8901 VL - 6 SP - 57 EP - 61 PB - Royal Society CY - London ER - TY - JOUR A1 - D'Aprile, Iwan-Michelangelo T1 - Costuming Genders: Acting as an Invention of the Enlightenment JF - German history : the journal of the German History Societ Y1 - 2016 U6 - https://doi.org/10.1093/gerhis/ghv109 SN - 0266-3554 SN - 1477-089X VL - 34 SP - 138 EP - 139 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Schmidt, Katja A1 - Sachse, Rene A1 - Walz, Ariane T1 - Current role of social benefits in ecosystem service assessments JF - Landscape and urban planning : an international journal of landscape ecology, planning and design N2 - Ecosystem services have a significant impact on human wellbeing. While ecosystem services are frequently represented by monetary values, social values and underlying social benefits remain underexplored. The purpose of this study is to assess whether and how social benefits have been explicitly addressed within socio-economic and socio-cultural ecosystem services research, ultimately allowing a better understanding between ecosystem services and human well-being. In this paper, we reviewed 115 international primary valuation studies and tested four hypotheses associated to the identification of social benefits of ecosystem services using logistic regressions. Tested hypotheses were that (1) social benefits are mostly derived in studies that assess cultural ecosystem services as opposed to other ecosystem service types, (2) there is a pattern of social benefits and certain cultural ecosystem services assessed simultaneously, (3) monetary valuation techniques go beyond expressing monetary values and convey social benefits, and (4) directly addressing stakeholdeŕs views the consideration of social benefits in ecosystem service assessments. Our analysis revealed that (1) a variety of social benefits are valued in studies that assess either of the four ecosystem service types, (2) certain social benefits are likely to co-occur in combination with certain cultural ecosystem services, (3) of the studies that employed monetary valuation techniques, simulated market approaches overlapped most frequently with the assessment of social benefits and (4) studies that directly incorporate stakeholder's views were more likely to also assess social benefits. KW - Literature review KW - Non-monetary valuation KW - Monetary valuation KW - Social valuation Y1 - 2016 U6 - https://doi.org/10.1016/j.landurbplan.2016.01.005 SN - 0169-2046 SN - 1872-6062 VL - 149 SP - 49 EP - 64 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Erdossy, Julia A1 - Horvath, Viola A1 - Yarman, Aysu A1 - Scheller, Frieder W. A1 - Gyurcsanyi, Robert E. T1 - Electrosynthesized molecularly imprinted polymers for protein recognition JF - Trends in Analytical Chemistry N2 - Molecularly imprinted polymers (MIPs) for the recognition of proteins are expected to possess high affinity through the establishment of multiple interactions between the polymer matrix and the large number of functional groups of the target. However, while highly affine recognition sites need building blocks rich in complementary functionalities to their target, such units are likely to generate high levels of nonspecific binding. This paradox, that nature solved by evolution for biological receptors, needs to be addressed by the implementation of new concepts in molecular imprinting of proteins. Additionally, the structural variability, large size and incompatibility with a range of monomers made the development of protein MIPs to take a slow start. While the majority of MIP preparation methods are variants of chemical polymerization, the polymerization of electroactive functional monomers emerged as a particularly advantageous approach for chemical sensing application. Electropolymerization can be performed from aqueous solutions to preserve the natural conformation of the protein templates, with high spatial resolution and electrochemical control of the polymerization process. This review compiles the latest results, identifying major trends and providing an outlook on the perspectives of electrosynthesised protein-imprinted MIPs for chemical sensing. (C) 2016 Elsevier B.V. All rights reserved. KW - Molecularly imprinted polymers KW - Proteins KW - Surface imprinting KW - Electropolymerization KW - Nanostructuring KW - Hybrid nanofilms Y1 - 2016 U6 - https://doi.org/10.1016/j.trac.2015.12.018 SN - 0165-9936 SN - 1879-3142 VL - 79 SP - 179 EP - 190 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Doetterl, Sebastian A1 - Berhe, Asmeret Asefaw A1 - Nadeu, Elisabet A1 - Wang, Zhengang A1 - Sommer, Michael A1 - Fiener, Peter T1 - Erosion, deposition and soil carbon: A review of process-level controls, experimental tools and models to address C cycling in dynamic landscapes JF - Earth science reviews : the international geological journal bridging the gap between research articles and textbooks N2 - The role of soil erosion in terrestrial carbon (C) sequestration and release remains one of the most important uncertainties in our attempts to determine the potential of soils to mediate climate change. Despite its widely recognized importance for terrestrial C sequestration, to date, no Earth System Model (ESM) implements soil erosion effects on carbon cycling in sufficient detail. So far, available studies have mostly investigated the magnitude of erosional C transport and in-situ measurements of vertical C fluxes on the catchment or regional scale. Recognizing the need to adequately represent C erosion processes and controls in ESMs, we provide a comprehensive cross-disciplinary review on lateral C redistribution in the landscape and discuss the implications for bio-geochemical cycling of carbon. We present current knowledge on the role of erosional C distribution in controlling the stabilization and release of C in soils, taking into consideration the important geomorphic, ecological, hydrologic, pedologic and micro-climatic processes and controls that affect soil organic carbon (SOC) stock, fluxes, and persistence in dynamic landscapes. Further, we provide an overview on latest experimental and modelling approaches that are being used to investigate the role of erosion in the carbon cycle. Finally, to advance our understanding of the role of soil redistribution in biogeochemical cycles of essential elements, we discuss the most promising topics for future research in this field. (C) 2015 Elsevier B.V. All rights reserved. KW - Soil erosion KW - Soil deposition KW - Carbon redistribution KW - Terrestrial C sink Y1 - 2016 U6 - https://doi.org/10.1016/j.earscirev.2015.12.005 SN - 0012-8252 SN - 1872-6828 VL - 154 SP - 102 EP - 122 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bacskai-Atkari, Julia T1 - Descriptive typology and linguistic theory: A study in the morphosyntax of relative clauses JF - Acta linguistica Hungarica : an international journal of linguistics Y1 - 2016 SN - 1216-8076 SN - 1588-2624 VL - 63 SP - 97 EP - 112 PB - Akadémiai Kiadó CY - Budapest ER - TY - JOUR A1 - Haßler, Gerda T1 - French in the Baroque and Enlightenment. Studies on the Linguistic Thinking in Germany in the 17th and 18th Centuries JF - Zeitschrift für Romanische Philologie Y1 - 2016 U6 - https://doi.org/10.1515/zrp-2016-0014 SN - 0049-8661 SN - 1865-9063 VL - 132 SP - 279 EP - 286 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Höne, Christin T1 - The Musical Novel: Imitation of Musical Structure, Performance and Reception in Contemporary Fiction JF - Geophysical research letters Y1 - 2016 U6 - https://doi.org/10.1093/ml/gcw001 SN - 0027-4224 SN - 1477-4631 VL - 97 SP - 190 EP - 191 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Linnik, Anastasia A1 - Bastiaanse, Roelien A1 - Höhle, Barbara T1 - Discourse production in aphasia: a current review of theoretical and methodological challenges JF - Aphasiology : an international, interdisciplinary journal N2 - Background: Discourse abilities play an important role in the assessment, classification, and therapy outcome evaluation of people with aphasia. Discourse production in aphasia has been studied quite extensively in the last 15 years. Nevertheless, many questions still do not have definitive answers.Aims: The aim of this review is to present the current situation in the research on a number of crucial aspects of discourse production in aphasia, focusing on methodological progress and related challenges. This review continues the discussion of the core themes in the field, aiming to render it as up-to-date as possible.Main Contribution: The review focuses on a number of unexplored theoretical issues, specifically, the interface between micro- and macrolinguistic abilities, and the relationship between linguistic competence and communicative success in aphasia. The emphasis on theoretical challenges, along with the thorough discussion of methodological problems in the field, makes this review a starting point and a comprehensive information source for researchers planning to address language production in people with aphasia.Conclusion: Although the picture is not yet complete, recent advancements lead to a better understanding of the processes involved in aphasic discourse production. Different approaches provide insights into the complex multifaceted nature of discourse-level phenomena; however, methodological issues, including low comparability, substantially slow down the progress in the field. KW - Discourse production KW - aphasia Y1 - 2016 U6 - https://doi.org/10.1080/02687038.2015.1113489 SN - 0268-7038 SN - 1464-5041 VL - 30 SP - 765 EP - 800 PB - Copernicus CY - Abingdon ER -