TY - JOUR A1 - Langenhan, Jennifer A1 - Jaeger, Carsten A1 - Baum, Katharina A1 - Simon, Mareike A1 - Lisec, Jan T1 - A flexible tool to correct superimposed mass isotopologue distributions in GC-APCI-MS flux experiments JF - Metabolites N2 - The investigation of metabolic fluxes and metabolite distributions within cells by means of tracer molecules is a valuable tool to unravel the complexity of biological systems. Technological advances in mass spectrometry (MS) technology such as atmospheric pressure chemical ionization (APCI) coupled with high resolution (HR), not only allows for highly sensitive analyses but also broadens the usefulness of tracer-based experiments, as interesting signals can be annotated de novo when not yet present in a compound library. However, several effects in the APCI ion source, i.e., fragmentation and rearrangement, lead to superimposed mass isotopologue distributions (MID) within the mass spectra, which need to be corrected during data evaluation as they will impair enrichment calculation otherwise. Here, we present and evaluate a novel software tool to automatically perform such corrections. We discuss the different effects, explain the implemented algorithm, and show its application on several experimental datasets. This adjustable tool is available as an R package from CRAN. KW - mass isotopologue distribution KW - enrichment calculation KW - flux KW - experiments KW - atmospheric pressure chemical ionization KW - R package KW - CorMID Y1 - 2022 U6 - https://doi.org/10.3390/metabo12050408 SN - 2218-1989 VL - 12 IS - 5 PB - MDPI CY - Basel ER - TY - INPR A1 - Kohler, Ulrich T1 - Maintaining quality T2 - Survey research methods N2 - Survey Research Methods has slightly revised its publication policies. Firstly, starting with the publication of this Editorial, SRM will accept - under specified conditions - manuscripts that discuss experiments in non-probability samples for peer-review. Secondly, SRM will require authors to publish replication materials of their study as Online supplement to their article. Finally, Survey Research Methods will publish replication studies of articles published in the journal. This Editorial gives reasons for these changes. KW - Editorial policies KW - non-probability samples KW - experiments KW - TOP-Guidelines Y1 - 2015 SN - 1864-3361 VL - 9 IS - 3 SP - 139 EP - 140 PB - European Survey Research Association CY - Duisburg ER - TY - JOUR A1 - Gerhard, Reimund A1 - Kacprzyk, Ryszard T1 - Paul Böning - early electret researcher in Shanghai and Wroclaw (1922-1945) JF - IEEE transactions on dielectrics and electrical insulation N2 - The scientific career and the research activities of Paul Boening, especially during his tenures at Tongji University in Shanghai (Woosung Campus, 1922-1936) and the Technical University of Wroclaw (TH Breslau, 1936-1945), are briefly reviewed. In particular, Boening's pioneering investigations in the area of electrets and space charge in dielectrics are emphasized. We attempt to shed some light on the significant achievements of a virtually unknown contributor to the early history of electrets and of space-charge research and high-voltage engineering, during the 1920s and 1930s. It should be noted that dielectrics research was a truly international endeavor already at that time. KW - dielectrics KW - electrets KW - electrostatic KW - experiments KW - (high-)voltage measurements KW - space charge Y1 - 2022 U6 - https://doi.org/10.1109/TDEI.2022.3168372 SN - 1070-9878 SN - 1558-4135 VL - 29 IS - 3 SP - 853 EP - 858 PB - Institute of Electrical and Electronics Engineers CY - New York, NY ER - TY - JOUR A1 - Ganghof, Steffen T1 - Research Design in Political Science - Causal perspectives versus contrastive theory testing JF - Austrian journal of political science N2 - Die politikwissenschaftliche Literatur unterscheidet zwei Grundtypen von Forschungsdesigns: x- und y-zentriert. Dieser Beitrag argumentiert, dass ein „kontrastives“ Forschungsdesign als dritter Grundtyp abgegrenzt werden sollte. Die drei Designs unterscheiden sich durch die Anzahl der betrachteten Theorien und dadurch, ob mehrere Theorien konkurrierend oder komplementär sind. Die typologische Abgrenzung des kontrastiven Designs verdeutlicht auch die Vor- und Nachteile x- und y-zentrierter Designs. Anhand verschiedener Beispielstudien (experimentell und nicht-experimentell, quantitativ und qualitativ) werden die Charakteristika der drei Designs sowie ihre Kombinationsmöglichkeiten herausgearbeitet. Darüber hinaus wird das kontrastive Design als verbindendes Element zwischen den quantitativen und qualitativen Forschungs-„Kulturen“ hervorgehoben. The political science literature distinguishes two basic types of research designs: x- and y-centered. The article argues for the distinction of a third basic type: the "contrastive" design. The three designs differ in the number of relevant theories and in whether they see theories as competing or complementary. The typological differentiation of the contrastive research design helps to clarify the pros and cons of x- and y-centered designs. The article uses exemplary studies (experimental and observational, quantitative and qualitative) to illustrate the characteristics of the three designs as well as the possibilities of combining them. The contrastive design also constitutes a common element of the quantitative and qualitative research, "cultures". KW - Forschungsdesign, kausale Perspektiven, Theorietest, x-zentriert, y-zentriert, Experimente KW - research design KW - causal perspectives KW - theory test KW - effects of causes KW - causes of effects KW - experiments Y1 - 2016 U6 - https://doi.org/10.15203/ozp.1037.vol45iss1 SN - 2313-5433 VL - 45 SP - 1 EP - 12 PB - Österreichische Gesellschaft für Politikwissenschaft CY - Wien ER - TY - JOUR A1 - Huber, Robert A1 - Rigling, Andreas A1 - Bebi, Peter A1 - Brand, Fridolin Simon A1 - Briner, Simon A1 - Buttler, Alexandre A1 - Elkin, Che A1 - Gillet, Francois A1 - Gret-Regamey, Adrienne A1 - Hirschi, Christian A1 - Lischke, Heike A1 - Scholz, Roland Werner A1 - Seidl, Roman A1 - Spiegelberger, Thomas A1 - Walz, Ariane A1 - Zimmermann, Willi A1 - Bugmann, Harald T1 - Sustainable land use in Mountain Regions under global change synthesis across scales and disciplines JF - Ecology and society : a journal of integrative science for resilience and sustainability N2 - Mountain regions provide essential ecosystem goods and services (EGS) for both mountain dwellers and people living outside these areas. Global change endangers the capacity of mountain ecosystems to provide key services. The Mountland project focused on three case study regions in the Swiss Alps and aimed to propose land-use practices and alternative policy solutions to ensure the provision of key EGS under climate and land-use changes. We summarized and synthesized the results of the project and provide insights into the ecological, socioeconomic, and political processes relevant for analyzing global change impacts on a European mountain region. In Mountland, an integrative approach was applied, combining methods from economics and the political and natural sciences to analyze ecosystem functioning from a holistic human-environment system perspective. In general, surveys, experiments, and model results revealed that climate and socioeconomic changes are likely to increase the vulnerability of the EGS analyzed. We regard the following key characteristics of coupled human-environment systems as central to our case study areas in mountain regions: thresholds, heterogeneity, trade-offs, and feedback. Our results suggest that the institutional framework should be strengthened in a way that better addresses these characteristics, allowing for (1) more integrative approaches, (2) a more network-oriented management and steering of political processes that integrate local stakeholders, and (3) enhanced capacity building to decrease the identified vulnerability as central elements in the policy process. Further, to maintain and support the future provision of EGS in mountain regions, policy making should also focus on project-oriented, cross-sectoral policies and spatial planning as a coordination instrument for land use in general. KW - adaptive management KW - climate change KW - ecosystem services KW - experiments KW - interdisciplinary research KW - land-use change KW - modeling KW - transdisciplinary research Y1 - 2013 U6 - https://doi.org/10.5751/ES-05499-180336 SN - 1708-3087 VL - 18 IS - 3 PB - Resilience Alliance CY - Wolfville ER - TY - JOUR A1 - Grubic, Mira A1 - Wierzba, Marta T1 - The German additive particle noch BT - testing the role of topic situations JF - Glossa : a journal of general linguistics N2 - The particle noch (‘still’) can have an additive reading similar to auch (‘also’). We argue that both particles indicate that a previously partially answered QUD is re-opened to add a further answer. The particles differ in that the QUD, in the case of auch, can be re-opened with respect to the same topic situation, whereas noch indicates that the QUD is re-opened with respect to a new topic situation. This account predicts a difference in the accommodation behavior of the two particles. We present an experiment whose results are in line with this prediction. KW - additive particles KW - noch KW - auch KW - German KW - topic situation KW - semantics KW - experiments Y1 - 2020 U6 - https://doi.org/10.5334/gjgl.1275 SN - 2397-1835 VL - 6 IS - 1 PB - Ubiquity Press CY - London ER - TY - GEN A1 - Grubic, Mira A1 - Wierzba, Marta T1 - The German additive particle noch BT - testing the role of topic situations T2 - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe N2 - The particle noch (‘still’) can have an additive reading similar to auch (‘also’). We argue that both particles indicate that a previously partially answered QUD is re-opened to add a further answer. The particles differ in that the QUD, in the case of auch, can be re-opened with respect to the same topic situation, whereas noch indicates that the QUD is re-opened with respect to a new topic situation. This account predicts a difference in the accommodation behavior of the two particles. We present an experiment whose results are in line with this prediction. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 709 KW - additive particles KW - noch KW - auch KW - German KW - topic situation KW - semantics KW - experiments Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-510049 SN - 1866-8364 IS - 709 ER - TY - JOUR A1 - Simik, Radek A1 - Wierzba, Marta T1 - The role of givenness, presupposition, and prosody in Czech word order: An experimental study JF - Semantics and pragmatics KW - givenness KW - presupposition KW - prosody KW - Czech KW - scrambling KW - acceptability judgments KW - experiments Y1 - 2015 U6 - https://doi.org/10.3765/sp.8.3 SN - 1937-8912 VL - 8 PB - Linguistic Society of America CY - Washington ER -