TY - JOUR A1 - Wright, Michelle F. A1 - Wachs, Sebastian T1 - Problematic online gaming, subjective health complaints, and depression among adolescent gamers from the United States BT - the role of console-gaming aggression JF - Journal of children and media N2 - The purpose of this study was to examine the longitudinal relationship between problematic online gaming and subjective health complaints and depressive symptoms, and the moderation of console-gaming aggression (i.e. verbal aggression, camping, trolling) in this relationship. Participants were 202 adolescents (86% boys; M age = 12.99 years) in the 7(th) or 8(th) grade who played first-person shooter games. They completed questionnaires on problematic online gaming, console-gaming aggression, subjective health complaints, and depressive symptoms. Six months later (Time 2), they completed questionnaires on subjective health complaints and depressive symptoms again. Findings revealed that problematic online gaming and console-gaming aggression were positive predictors of Time 2 subjective health complaints and depressive symptoms, while controlling for Time 1 levels and gender. Moderating effects were found as well, indicating that high levels of console-gaming aggression increased the positive relationship between problematic online gaming and depressive symptoms. These effects were also replicated for verbal aggression, problematic online gaming, and subjective health complaints. These findings suggest the importance of considering the implications of console-gaming aggression and problematic online gaming for the physical and mental health of adolescents. IMPACT SUMMARY Prior State of Knowledge. Problematic online gaming and aggressive behaviors are linked to negative outcomes, including depression and subjective health complaints. Longitudinal research further supports this connection for depression, but not for subjective health complaints or various types of aggression via console games. Novel Contributions. Few studies have focused on various types of aggression and the longitudinal associations among problematic online gaming, depression, and subjective health complaints, while controlling for previous levels of depression and subjective health complaints. The present research addresses these gaps. Practical Implications. Findings of the present research has implications for clinicians and researchers concerned with identifying adolescents who might be at risk for negative outcomes. KW - Depression KW - subjective health complaints KW - problematic online gaming KW - first-person shooter games KW - aggression Y1 - 2022 U6 - https://doi.org/10.1080/17482798.2022.2036211 SN - 1748-2798 SN - 1748-2801 VL - 16 IS - 3 SP - 451 EP - 460 PB - Routledge, Taylor & Francis Group CY - Abingdon ER - TY - JOUR A1 - Tetzner, Julia A1 - Kliegl, Reinhold A1 - Krahé, Barbara A1 - Busching, Robert A1 - Esser, Günter T1 - Developmental problems in adolescence BT - a person-centered analysis across time and domains JF - Journal of Applied Developmental Psychology N2 - This longitudinal study investigated patterns of developmental problems across depression, aggression, and academic achievement during adolescence, using two measurement points two years apart (N = 1665; age T1: M = 13.14; female = 49.6%). Latent Profile Analyses and Latent Transition Analyses yielded four main findings: A three-type solution provided the best fit to the data: an asymptomatic type (i.e., low problem scores in all three domains), a depressed type (i.e., high scores in depression), an aggressive type (i.e., high scores in aggression). Profile types were invariant over the two data waves but differed between girls and boys, revealing gender specific patterns of comorbidity. Stabilities over time were high for the asymptomatic type and for types that represented problems in one domain, but moderate for comorbid types. Differences in demographic variables (i.e., age, socio-economic status) and individual characteristics (i.e., self-esteem, dysfunctional cognitions, cognitive capabilities) predicted profile type memberships and longitudinal transitions between types. KW - Adolescence KW - Person-centered approach KW - Depression KW - Aggression KW - Academic achievement Y1 - 2017 U6 - https://doi.org/10.1016/j.appdev.2017.08.003 SN - 0193-3973 SN - 1873-7900 VL - 53 SP - 40 EP - 53 PB - Elsevier CY - New York ER - TY - JOUR A1 - Schmid, Brigitte A1 - Blomeyer, Dorothea A1 - Buchmann, Arlette F. A1 - Trautmann-Villalba, Patricia A1 - Zimmermann, Ulrich S. A1 - Schmidt, Martin H. A1 - Esser, Günter A1 - Banaschewski, Tobias A1 - Laucht, Manfred T1 - Quality of early mother-child interaction associated with depressive psychopathology in the offspring - a prospective study from infancy to adulthood JF - Journal of psychiatric research N2 - Evidence from animal research has revealed that less maternal care results in disturbed emotionality in the offspring. In the present study, the long-term impact of maternal responsiveness and stimulation during early mother child interaction on depressive psychopathology was examined until adulthood. Data are from an epidemiological cohort study of the long-term outcome of early risk factors assessed at birth. At age 3 months, mothers and infants were videotaped during a nursing and playing situation. Maternal responsiveness and stimulation as well as infant responsiveness were evaluated by trained raters. At age 19 years, 314 participants (145 males, 169 females) were characterized on measures of depression through interview and questionnaire. In addition, measures of depression and anxiety were available from assessments in childhood. Results indicated that less maternal stimulation during early interaction was associated with a higher risk of depression in the offspring until the age of 19 years. In addition, children of less stimulating mothers showed more depressive symptoms at age 19 years and displayed more anxiety and depressive symptoms between the ages of 4.5 and 15 years. In contrast, maternal responsiveness was unrelated to children's outcome. In accordance with findings from animal research, the present study provides first longitudinal evidence in humans of a continuous and long-term influence of early maternal interaction behavior on the offspring's psychological adjustment until adulthood. The results suggest that the amount of maternally initiated contact behavior in a very early developmental stage may be crucial for children's mental health, regardless of child and maternal responsiveness. KW - Depression KW - Mother-infant interaction KW - Longitudinal study KW - Young adulthood KW - Infancy Y1 - 2011 U6 - https://doi.org/10.1016/j.jpsychires.2011.05.010 SN - 0022-3956 VL - 45 IS - 10 SP - 1387 EP - 1394 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Reichel, Martin A1 - Hoenig, Stefanie A1 - Liebisch, Gerhard A1 - Lüth, Anja A1 - Kleuser, Burkhard A1 - Gulbins, Erich A1 - Schmitz, Gerd A1 - Kornhuber, Johannes T1 - Alterations of plasma glycerophospholipid and sphingolipid species in male alcohol-dependent patients JF - Biochimica et biophysica acta : Molecular and cell biology of lipids N2 - Background: Alcohol abuse is a major risk factor for somatic and neuropsychiatric diseases. Despite their potential clinical importance, little is known about the alterations of plasma glycerophospholipid (GPL) and sphingolipid (SPL) species associated with alcohol abuse. Methods: Plasma GPL and SPL species were quantified using electrospray ionization tandem mass spectrometry in samples from 23 male alcohol-dependent patients before and after detoxification, as well as from 20 healthy male controls. Results: A comparison of alcohol-dependent patients with controls revealed higher phosphatidylcholine (PC; P-value = 0.008) and phosphatidylinositol (PI; P-value = 0.001) concentrations in patients before detoxification, and higher PI (P-value = 0.001) and phosphatidylethanolamine (PE)-based plasmalogen (PEP; P-value = 0.003) concentrations after detoxification. Lysophosphatidylcholines (LPC) were increased by acute intoxication (P-value = 0.002). Sphingomyelin (SM) concentration increased during detoxification (P-value = 0.011). The concentration of SM 23:0 was lower in patients (P-value = 2.79 x 10(-5)), and the concentrations of ceramide Cer d18:1/16:0 and Cer d18:1/18:0 were higher in patients (P-value = 2.45 x 10(-5) and 3.73 x 10(-5)). Activity of lysosomal acid sphingomyelinase (ASM) in patients correlated positively with the concentrations of eight LPC species, while activity of secreted ASM was inversely correlated with several PE, PI and PC species, and positively correlated with the molar ratio of PC to SM (Pearson's r = 0.432; P-value = 0.039). Conclusion: Plasma concentrations of numerous GPL and SPL species were altered in alcohol-dependent patients. These molecules might serve as potential biomarkers to improve the diagnosis of patients and to indicate health risks associated with alcohol abuse. Our study further indicates that there are strong interactions between plasma GPL concentrations and SPL metabolism. (C) 2015 Elsevier B.V. All rights reserved. KW - Acid sphingomyelinase KW - Alcohol dependence KW - Anxiety KW - Cardiovascular KW - Case-control study KW - Ceramide KW - Clinical KW - Depression KW - Diagnostic KW - Disease KW - Glycerophospholipids KW - Lysophosphatidylcholines KW - Mass spectrometry KW - Phosphatidylcholines KW - Phosphatidylinositols KW - Plasma KW - Plasmalogens KW - Sphingolipids KW - Sphingomyelin KW - Tandem mass spectrometry Y1 - 2015 U6 - https://doi.org/10.1016/j.bbalip.2015.08.005 SN - 1388-1981 SN - 0006-3002 VL - 1851 IS - 11 SP - 1501 EP - 1510 PB - Elsevier CY - Amsterdam ER - TY - THES A1 - Pérez Chaparro, Camilo Germán Alberto T1 - Non-HIV comorbidities and exercise in German people living with HIV T1 - Nicht-HIV-Komorbiditäten und Bewegung bei deutschen Menschen, die mit HIV leben N2 - The post-antiretroviral therapy era has transformed HIV into a chronic disease and non-HIV comorbidities (i.e., cardiovascular and mental diseases) are more prevalent in PLWH. The source of these non-HIV comorbidities aside from traditional risk factor include HIV infection, inflammation, distorted immune activation, burden of chronic diseases, and unhealthy lifestyle like sedentarism. Exercise is known for its beneficial effects in mental and physical health; reasons why exercise is recommended to prevent and treat difference cardiovascular and mental diseases in the general population. This cumulative thesis aimed to comprehend the relation exercise has to non-HIV comorbidities in German PLWH. Four studies were conducted to 1) understand exercise effects in cardiorespiratory fitness and muscle strength on PLWH through a systematic review and meta-analyses and 2) determine the likelihood of German PLWH developing non-HIV comorbidities, in a cross-sectional study. Meta-analytic examination indicates PLWH cardiorespiratory fitness (VO2max SMD = 0.61 ml·kg·min-1, 95% CI: 0.35-0.88, z = 4.47, p < 0.001, I2 = 50%) and strength (of remark lowerbody strength by 16.8 kg, 95% CI: 13–20.6, p< 0.001) improves after an exercise intervention in comparison to a control group. Cross-sectional data suggest exercise has a positive effect on German PLWH mental health (less anxiety and depressive symptoms) and protects against the development of anxiety (PR: 0.57, 95%IC: 0.36 – 0.91, p = 0.01) and depression (PR: 0.62, 95%IC: 0.41 – 0.94, p = 0.01). Likewise, exercise duration is related to a lower likelihood of reporting heart arrhythmias (PR: 0.20, 95%IC: 0.10 – 0.60, p < 0.01) and exercise frequency to a lower likelihood of reporting diabetes mellitus (PR: 0.40, 95%IC: 0.10 – 1, p < 0.01) in German PLWH. A preliminary recommendation for German PLWH who want to engage in exercise can be to exercise ≥ 1 time per week, at an intensity of 5 METs per session or > 103 MET·min·day-1, with a duration ≥ 150 minutes per week. Nevertheless, further research is needed to comprehend exercise dose response and protective effect for cardiovascular diseases, anxiety, and depression in German PLWH. N2 - In der Zeit seit der antiretroviralen Therapie hat sich HIV zu einer chronischen Erkrankung entwickelt und Nicht-HIV-Komorbiditäten, z.B. Herz-Kreislauf-Erkrankungen und psychische Erkrankungen, treten bei Menschen, die mit HIV leben, häufiger auf. Die Herkunft dieser Nicht-HIV-Komorbiditäten, neben den traditionellen Risikofaktoren, sind HIV-Infektion, chronische Entzündung, eine gestörte Immunaktivierung, chronische Erkrankungen und eine ungesunde Lebensweise wie Bewegungsmangel. Bewegung ist bekannt für seine positive Wirkung auf die mentale und körperliche Gesundheit; das ist der Grund, warum Bewegung in der Prävention und der Behandlung verschiedener Herz-Kreislauf- und psychischer Erkrankungen in der Allgemeinbevölkerung empfohlen wird. Ziel dieser kumulativen Arbeit war es, den Zusammenhang zwischen körperlicher Bewegung und nicht-HIV-Komorbiditäten bei deutschen Menschen, die mit HIV leben zu untersuchen. Vier Studien wurden durchgeführt, um 1) die Auswirkungen von Bewegung auf die kardiorespiratorische Fitness und die Muskelkraft von HIV-Infizierten durch eine systematische Übersichtsarbeit und Meta-Analysen zu verstehen und 2) zu bestimmen, ob HIV-positive Menschen, die Bewegung treiben, entwickeln einen Nicht-HIV-Komorbiditäten. Die metaanalytische Untersuchung zeigt, dass sich die kardiorespiratorische Fitness (VO2max SMD = 0.61 mlkgmin-1, 95 % CI: 0.35-0.88, z = 4.47, p < 0.001, I2 = 50 %) und Kraft (Besonders in den unteren Extremitäten 16.8 kg, 95 % CI: 13–20.6, p< 0.001) nach einer Trainingsintervention im Vergleich zu einer Kontrollgruppe verbessert. Querschnittdaten deuten darauf hin, dass Bewegung eine positive Wirkung auf die psychische Gesundheit den deutschen Menschen, die mit HIV leben hat (weniger Angst und depressive Symptome) und vor der Entwicklung von Angst (PR: 0,57, 95 % IC: 0,36 - 0,91, p = 0,01) und Depression (PR: 0,62, 95 % IC: 0,41 - 0,94, p = 0,01) schützt. Ebenso geht die Dauer der Bewegung mit einer geringeren Wahrscheinlichkeit für Herzrhythmusstörungen einher, (PR: 0,20, 95 % IC: 0,10 - 0,60, p < 0,01). Eine vorläufige Empfehlung für deutsche Menschen, die mit HIV leben und die sich sportlich betätigen wollen, kann sein, ³ 1-mal pro Woche mit einer Intensität von 5 METs und einer Dauer von ³ 60 Minuten zu trainieren. Dennoch sind weitere Forschungen erforderlich, um die Dosiswirkung und die schützende Wirkung von Bewegung auf Herz-Kreislauf-Erkrankungen, Angst und Depression bei deutschen Menschen, die mit HIV leben zu verstehen. KW - HIV KW - cardiovascular disease KW - anxiety KW - depression KW - exercise KW - Menschen, die mit HIV leben KW - Angst KW - Depression KW - kardiovaskuläre Erkrankungen KW - Bewegung Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-560842 ER - TY - JOUR A1 - Pitzer, Martina A1 - Esser, Günter A1 - Schmidt, Martin H. A1 - Hohm, Erika A1 - Banaschewski, Tobias A1 - Laucht, Manfred T1 - Child regulative temperament as a mediator of parenting in the development of depressive symptoms BT - a longitudinal study from early childhood to preadolescence JF - Journal of neural transmission N2 - Child temperament as well as parenting behaviors have been linked to adolescent depression. Beyond their main effects, the interplay between these factors is of interest. For example, in an interactive model, a differential susceptibility of temperamental variants to parenting has been suggested. However, so far, the differential susceptibility hypothesis has mostly been studied with a focus on externalizing disorders. On the other hand, parenting may shape the child’s temperament and vice versa in a transactional process. In a prospective, longitudinal at-risk sample (163 boys, 176 girls), we assessed emotional (easy–difficult) and regulative (self-control) temperament at ages 4.5, and 8 years, respectively, as well as parenting quality at age 4.5 years using the HOME inventory. Hierarchical linear regression analysis was used to investigate the prediction of depressive symptoms at age 11, measured by the Child Depression Inventory, including interaction terms between the temperament variable and parenting. We additionally tested whether parenting was mediated by child temperament. As previously reported, both self-control and parenting were longitudinally associated with preadolescent depressive symptoms. There were no interactive effects between temperament and parenting. However, the effects of parenting were partly mediated by self-control. Our data do not support a differential susceptibility of temperamental variants in the development of preadolescent depression. However, our results are in line with the assumption that parenting may shape young children’s temperament, with positive parenting in the early childhood fostering the development of regulative temperament. KW - Temperament KW - Parenting KW - Children KW - Depression KW - Parent-child-interaction Y1 - 2017 U6 - https://doi.org/10.1007/s00702-017-1682-2 SN - 0300-9564 SN - 1435-1463 VL - 124 SP - 631 EP - 641 PB - Springer CY - Wien ER - TY - THES A1 - Pietrek, Anou F. T1 - Basic psychological needs and depression in the context of health and exercise N2 - Depressive Erkrankungen gehen mit verminderter Lebenszufriedenheit und reduzierter Arbeitsfähigkeit einher. Die Wartezeit für eine Psychotherapie beträgt in Deutschland derzeit zwischen drei und sechs Monaten. Demnach besteht Bedarf an alternativen, gleichwertigen evidenzbasierten Behandlungsmöglichkeiten, die den Betroffenen niedrigschwellig zugänglich gemacht werden. Eine Vielzahl an empirischen Studien belegt die Wirksamkeit von Sport bei leichten und mittelschweren Depressionen. Zur weiterführenden Konzeption und Qualitätssicherung von Sport als Behandlungsoption ist es notwendig die konkreten Wirkmechanismen zu verstehen. Neben physiologischen spielen auch psychologische Faktoren eine Rolle im Wirkungsgeschehen. Als Metatheorie menschlichen Erlebens und Verhaltens bietet die Selbstbestimmungstheorie (engl.: Self-Determination Theory; SDT) einen nützlichen Bezugsrahmen zum Verständnis psychologischer Wirkmechanismen mit konkreten Ableitungen für die Behandlungspraktik. Die konzeptionelle Erweiterung der SDT um die Frustration psychologischer Grundbedürfnisse erweist sich neben der Bedürfnisbefriedigung zunehmend als hilfreich bei der Untersuchung von psychischen Erkrankungen. Der erste Teil dieser Dissertation besteht aus zwei Publikationen, die relevante Messinstrumente in dem genannten Kontext validieren. Der erste Fragebogen misst das Ausmaß an allgemein erlebter Befriedigung und Frustration der psychologischen Grundbedürfnisse nach Autonomie, Kompetenz und sozialer Eingebundenheit. Der zweite Fragebogen erhebt die erlebte Bedürfnisbefriedigung durch die anleitende Person (hier: Sporttherapeut*in). Der zweite Teil der Dissertation umfasst zwei Publikationen, welche die Befriedigung und Frustration der psychologischen Grundbedürfnisse bei depressiven Symptomen untersuchen und einordnen. Es werden die Unterschiede im Ausmaß an Bedürfnisbefriedigung und Bedürfnisfrustration zwischen einer Stichprobe mit Depression mit einer Stichprobe ohne depressive Symptome untersucht. Der Zusammenhang zwischen Bedürfnisfrustration und depressiven Symptomen wird im Kontext etablierter pathologischer Prozesse (Emotionsdysregulation, Rumination) eingeordnet. Die Hauptergebnisse dieser Arbeiten zeigen, dass die SDT durch die Erweiterung der Basic Psychological Needs Theory um die Dimension der Bedürfnisfrustration ein nun breiteres Spektrum auf dem Gesundheit-Krankheit-Kontinuum abbildet. Dabei fokussiert die SDT auf die psychologische Wirkung von sozialen Umwelten. Neben der Nichterfüllung der psychologischen Grundbedürfnisse ist es vor allem die Bedürfnisfrustration, die einen allgemeinen Vulnerabilitätsfaktor für das Vorkommen psychologischer Erkrankungen darstellt. Zudem weist die unausgewogene Befriedigung der psychologischen Grundbedürfnisse möglicherweise auf ein konflikthaftes Erleben zwischen den Bedürfnissen hin. Für die Behandlungspraktik abzuleiten ist, dass eine autonomieunterstützende Atmosphäre, die die ausgewogene Befriedigung aller drei Bedürfnisse ermöglicht, zentral für den Behandlungserfolg ist. N2 - Depressive disorders are associated with reduced life satisfaction and ability to work. The waiting time for psychotherapy in Germany is currently between three and six months. Accordingly, there is a need for alternative, evidence-based treatment options that are made accessible to patients at a low threshold. A large number of empirical studies prove the effectiveness of exercise in mild and moderate depression. For further conceptualization and quality assurance of exercise as a treatment option, it is necessary to understand the concrete mechanisms of action. In addition to physiological factors, psychological factors also play a role in the effect. As a meta-theory of human experience and behavior, Self-Determination Theory (SDT) provides a useful frame for understanding psychological mechanisms of action with concrete implications for treatment practice. The conceptual extension of SDT to include the frustration of basic psychological needs in addition to need satisfaction is proving useful in the study of mental illness. The first part of this dissertation consists of two publications that validate relevant measurement instruments in this context. The first questionnaire measures the extent of generally experienced satisfaction and frustration of the basic psychological needs for autonomy, competence, and relatedness. The second questionnaire measures the experienced satisfaction of needs by the instructor (here: exercise therapist). The second part of the dissertation includes two publications that examine and classify the satisfaction and frustration of basic psychological needs in depressive symptoms. Differences in the extent of need satisfaction and need frustration between a sample with depression and a sample without depressive symptoms are examined. Further, the relationship between need frustration and depressive symptoms is placed in the context of established pathological processes (emotional dysregulation, rumination). The main findings of this work show that by adding the dimension of need frustration to Basic Psychological Needs Theory, SDT now covers a broader spectrum on the health-disease continuum. In doing so, SDT focuses on the psychological impact of social environments. In addition to the nonfulfillment of basic psychological needs, it is primarily experienced need frustration that is a general vulnerability factor for the occurrence of psychological illness. Moreover, the unbalanced satisfaction of basic psychological needs possibly indicates a conflicting experience between the needs. For the treatment practice it can be deduced that an autonomy-supporting atmosphere, which enables the balanced satisfaction of all three needs, is central for the treatment success. T2 - Psychologische Grundbedürfnisse und Depression im Kontext von Gesundheit und Sport KW - basic psychological needs KW - depression KW - exercise KW - autonomy support KW - treatment KW - psychologische Grundbedürfnisse KW - Depression KW - Sport KW - Autonomieunterstützung KW - Behandlung Y1 - 2023 ER - TY - JOUR A1 - Paslakis, Georgios A1 - Buchmann, Arlette F. A1 - Westphal, Sabine A1 - Banaschewski, Tobias A1 - Hohm, Erika A1 - Zimmermann, Ulrich S. A1 - Laucht, Manfred A1 - Deuschle, Michael T1 - Intrauterine exposure to cigarette smoke is associated with increased ghrelin concentrations in adulthood JF - Neuroendocrinology : international journal for basic and clinical studies on neuroendocrine relationships N2 - Background: The appetite-stimulating hormone ghrelin is a fundamental regulator of human energy metabolism. A series of studies support the notion that long-term appetite and weight regulation may be already programmed in early life and it could be demonstrated that the intrauterine environment affects the ghrelin system of the offspring. Animal studies have also shown that intrauterine programming of orexigenic systems persists even until adolescence/adulthood. Methods: We hypothesized that plasma ghrelin concentrations in adulthood may be associated with the intrauterine exposure to cigarette smoke. We examined this hypothesis in a sample of 19-year-olds followed up since birth in the framework of the Mannheim Study of Children at Risk, an ongoing epidemiological cohort study of the long-term outcome of early risk factors. Results: As a main finding, we found that ghrelin plasma concentrations in young adults who had been exposed to cigarette smoke in utero were significantly higher than in those without prenatal smoke exposure. Moreover, individuals with intrauterine nicotine exposure showed a significantly higher prevalence of own smoking habits and lower educational status compared to those in the group without exposure. Conclusion: Smoking during pregnancy may be considered as an adverse intrauterine influence that may alter the endocrine-metabolic status of the offspring even until early adulthood. KW - Cigarette smoke KW - Depression KW - Energy metabolism KW - Epigenetics KW - Ghrelin KW - Intrauterine exposure KW - Nicotine Y1 - 2014 U6 - https://doi.org/10.1159/000363325 SN - 0028-3835 SN - 1423-0194 VL - 99 IS - 2 SP - 123 EP - 129 PB - Karger CY - Basel ER - TY - JOUR A1 - Meiser, Susanne A1 - Esser, Günter T1 - How dysfunctional are dysfunctional attitudes? BT - a threshold model of dysfunctional attitudes and depressive symptoms in children and adolescents JF - Cognitive Therapy and Research N2 - In order to clarify further the role of Beck’s vulnerability-stress model in the early development of depression, this longitudinal study tested a threshold model of dysfunctional attitudes in children and adolescents. An initially asymptomatic sample of 889 youths aged 9–18 years completed measures of dysfunctional attitudes and depressive symptoms. Twenty months later, participants reported stressful life events and current depressive symptoms. Results support a threshold view of cognitive vulnerability as only dysfunctional attitudes above a certain threshold significantly interacted with life events to predict depressive symptoms. Thus, findings suggest that dysfunctional attitudes must exceed a certain threshold to confer vulnerability to depressive symptomatology in youth. The term “dysfunctional” might therefore only apply to higher levels of the “dysfunctional attitudes” proposed by A. T. Beck. Results also indicate that studies using non-clinical samples may systematically underestimate the effect of dysfunctional attitudes when relying on conventional linear methods. KW - Cognitive vulnerability KW - Depression KW - Children KW - Adolescents KW - Dysfunctional attitudes KW - Threshold models Y1 - 2017 U6 - https://doi.org/10.1007/s10608-017-9842-0 SN - 0147-5916 SN - 1573-2819 VL - 41 SP - 730 EP - 744 PB - Springer CY - New York ER - TY - THES A1 - Meiser, Susanne T1 - Wie dysfunktional sind Dysfunktionale Einstellungen? T1 - How dysfunctional are dysfunctional attitudes? BT - dysfunktionale Kognitionen und Depression im Kindes- und Jugendalter BT - dysfunctional cognitions and depression in children and adolescents N2 - Im kognitiven Vulnerabilitäts-Stress-Modell der Depression von A.T. Beck (1967, 1976) spielen dysfunktionale Einstellungen bei der Entstehung von Depression in Folge von erlebtem Stress eine zentrale Rolle. Diese Theorie prägt seit Jahrzehnten die ätiologische Erforschung der Depression, jedoch ist die Bedeutung dysfunktionaler Einstellungen im Prozess der Entstehung einer Depression insbesondere im Kindes- und Jugendalter nach wie vor unklar. Die vorliegende Arbeit widmet sich einigen in der bisherigen Forschung wenig behandelten Fragen. Diese betreffen u. a. die Möglichkeit nichtlinearer Effekte dysfunktionaler Einstellungen, Auswirkungen einer Stichprobenselektion, Entwicklungseffekte sowie die Spezifität etwaiger Zusammenhänge für eine depressive Symptomatik. Zur Beantwortung dieser Fragen wurden Daten von zwei Messzeitpunkten der PIER-Studie, eines großangelegten Längsschnittprojekts über Entwicklungsrisiken im Kindes- und Jugendalter, genutzt. Kinder und Jugendliche im Alter von 9 bis 18 Jahren berichteten zweimal im Abstand von ca. 20 Monaten im Selbstberichtsverfahren über ihre dysfunktionalen Einstellungen, Symptome aus verschiedenen Störungsbereichen sowie über eingetretene Lebensereignisse. Die Ergebnisse liefern Evidenz für ein Schwellenmodell, in dem dysfunktionale Einstellungen unabhängig von Alter und Geschlecht nur im höheren Ausprägungsbereich eine Wirkung als Vulnerabilitätsfaktor zeigen, während im niedrigen Ausprägungsbereich keine Zusammenhänge zur späteren Depressivität bestehen. Eine Wirkung als Vulnerabilitätsfaktor war zudem nur in der Subgruppe der anfänglich weitgehend symptomfreien Kinder und Jugendlichen zu beobachten. Das Schwellenmodell erwies sich als spezifisch für eine depressive Symptomatik, es zeigten sich jedoch auch (teilweise ebenfalls nichtlineare) Effekte dysfunktionaler Einstellungen auf die Entwicklung von Essstörungssymptomen und aggressivem Verhalten. Bei 9- bis 13-jährigen Jungen standen dysfunktionale Einstellungen zudem in Zusammenhang mit einer Tendenz, Stress in Leistungskontexten herbeizuführen. Zusammen mit den von Sahyazici-Knaak (2015) berichteten Ergebnissen aus der PIER-Studie weisen die Befunde darauf hin, dass dysfunktionale Einstellungen im Kindes- und Jugendalter – je nach betrachteter Subgruppe – Ursache, Symptom und Konsequenz der Depression darstellen können. Die in der vorliegenden Arbeit gezeigten nichtlinearen Effekte dysfunktionaler Einstellungen und die Effekte der Stichprobenselektion bieten eine zumindest teilweise Erklärung für die Heterogenität früherer Forschungsergebnisse. Insgesamt lassen sie auf komplexe – und nicht ausschließlich negative – Auswirkungen dysfunktionaler Einstellungen schließen. Für eine adäquate Beurteilung der „Dysfunktionalität“ der von A.T. Beck so betitelten Einstellungen erscheint daher eine Berücksichtigung der betrachteten Personengruppe, der absoluten Ausprägungen und der fraglichen Symptomgruppen geboten. N2 - In A. T. Beck´s prominent vulnerability-stress-model of depression (Beck 1967, 1976), dysfunctional attitudes represent the key vulnerability factor of depression. This theory has stimulated etiological research on depression for decades. However, the significance of dysfunctional attitudes for the emergence of depression in children and adolescents remains somewhat elusive. This dissertation addresses some questions unanswered by past studies, e.g. the possibility of nonlinear effects of dysfunctional attitudes, the impact of subject selection procedures, developmental effects and the specificity of dysfunctional attitudes for depressive symptomatology. These questions were examined using data from two measurement points of the PIER study, a large longitudinal project on developmental risks in childhood and adolescence. Children and adolescents aged 9 – 18 years reported dysfunctional attitudes, symptoms from various domains and stressful life events twice with a mean interval between assessments of 20 months. Results suggest a threshold model of cognitive vulnerability, in which only dysfunctional attitudes exceeding a certain threshold conferred vulnerability to depressive symptoms, while dysfunctional attitudes below the threshold were unrelated to future depressive symptoms. These effects were invariant across gender and age. Moreover, vulnerability effects of dysfunctional attitudes were observable in initially non-symptomatic participants only. The threshold model of dysfunctional attitudes turned out to be specific for the depressive symptom domain. However, relationships of different shapes were detected between dysfunctional attitudes and the development of aggressive and eating disorder symptoms. Moreover, dysfunctional attitudes in 9 – 13-year old boys predicted non-interpersonal stress generation. Along with evidence from the PIER study reported by Sahyazici-Knaak (2015), results suggest that dysfunctional attitudes in children and adolescents may represent a cause, symptom and consequence of depression, depending on the sub-population in question. The nonlinear effects of dysfunctional attitudes detected in this study might, at least in part, offer an explanation for the inconsistent results of past studies. In sum, findings of this dissertation suggest complex – and not exclusively negative - effects of dysfunctional attitudes. Thus, a judgement of the actual “dysfunctionality” of the “dysfunctional attitudes” proposed by A. T. Beck seems to require a close consideration of the absolute level of attitudes as well as the sub-population and symptom domains in question. KW - Depression KW - Ätiologie KW - Kognition KW - dysfunktionale Einstellungen KW - Kinder KW - Jugendliche KW - kognitive Vulnerabilität KW - depression KW - etiology KW - cognition KW - dysfunctional attitudes KW - children KW - adolescents KW - cognitive vulnerability Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-412483 ER - TY - JOUR A1 - Laucht, Manfred A1 - Treutlein, Jens A1 - Blomeyer, Dorothea A1 - Buchmann, Arlette F. A1 - Schmidt, Martin H. A1 - Esser, Günter A1 - Jennen-Steinmetz, Christine A1 - Rietschel, Marcella A1 - Banaschewski, Tobias T1 - Interactive effects of corticotropin-releasing hormone receptor 1 gene and childhood adversity on depressive symptoms in young adults findings from a longitudinal study JF - European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology N2 - Accumulating research suggests a moderating role for the corticotropin-releasing hormone receptor 1 gene (CRHR1) in the association between childhood adversity and adult depression. The present study aims to replicate recent findings using different genetic variants and measures of early adversity assessed both prospectively and retrospectively. Data were collected in the context of an ongoing epidemiological cohort study following the outcome of early risk factors from birth into adulthood. 300 participants (137 males, 163 females) were genotyped for four CRHR1 SNPs (rs7209436, rs110402, rs242924, and rs17689882) and completed the Beck Depression Inventory at ages 19, 22 and 23 years. Childhood adversity was assessed using the Childhood Trauma Questionnaire and by a standardized parent interview yielding an index of family adversity. Our results indicate that CRHR1 and childhood adversity interacted to predict depressive symptoms in young adults. Specifically, we found that the impact of childhood maltreatment on adult depressive symptoms was significantly higher in individuals (i) with two copies of the CRHR1 TAT haplotype, and (ii) homozygous for the G allele of rs17689882. The interaction was demonstrated for exposure to childhood maltreatment as assessed by retrospective self-report, but not to prospectively ascertain objective family adversity. The present study partially replicates recent findings of a CRHR1 by childhood adversity interaction with regard to adult depression highlighting the subjective characteristics of the environmental pathogen that is operative in this interaction. KW - Corticotropin-releasing hormone receptor 1 gene KW - Depression KW - Maltreatment KW - Family adversity KW - Young adults KW - Gene-environment interaction Y1 - 2013 U6 - https://doi.org/10.1016/j.euroneuro.2012.06.002 SN - 0924-977X VL - 23 IS - 5 SP - 358 EP - 367 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kuhlmann, Stella A1 - Tschorn, Mira A1 - Arolt, Volker A1 - Beer, Katja A1 - Brandt, Julia A1 - Grosse, Laura A1 - Haverkamp, Wilhelm A1 - Müller-Nordhorn, Jacqueline A1 - Rieckmann, Nina A1 - Waltenberger, Johannes A1 - Warnke, Katharina A1 - Hellweg, Rainer A1 - Ströhle, Andreas T1 - Serum brain-derived neurotrophic factor and stability of depressive symptoms in coronary heart disease patients BT - a prospective study JF - Psychoneuroendocrinology : an international journal ; the official journal of the International Society of Psychoneuroendocrinology N2 - Objective: Brain-derived neurotrophic factor (BDNF) supports neurogenesis, angiogenesis, and promotes the survival of various cell types in the brain and the coronary system. Moreover, BDNF is associated with both coronary heart disease (CHD) and depression. The current study aims to investigate whether serum BDNF levels are associated with the course of depressive symptoms in CHD patients. Methods: At baseline, N = 225 CHD patients were enrolled while hospitalized. Of these, N = 190 (84%) could be followed up 6 months later. Depressive symptoms were assessed both at baseline and at the 6-months follow-up using the Patient Health Questionnaire (PHQ-9). Serum BDNF concentrations were measured using fluorometric Enzyme-linked immunosorbent assays (ELISA). Results: Logistic regression models showed that lower BDNF levels were associated with persistent depressive symptoms, even after adjustment for age, sex, smoking and potential medical confounders. The incidence of depressive symptoms was not related to lower BDNF levels. However, somatic comorbidity (as measured by the Charlson Comorbidity Index) was significantly associated with the incidence of depressive symptoms. Conclusions: Our findings suggest a role of BDNF in the link between CHD and depressive symptoms. Particularly, low serum BDNF levels could be considered as a valuable biomarker for the persistence of depressive symptoms among depressed CHD patients. KW - Brain-derived neurotrophic factor (BDNF) KW - Coronary heart disease (CHD) KW - Depression KW - Serum Y1 - 2016 U6 - https://doi.org/10.1016/j.psyneuen.2016.12.015 SN - 0306-4530 VL - 77 SP - 196 EP - 202 PB - Elsevier Science CY - Oxford ER - TY - JOUR A1 - Konrad, Marcel A1 - Jacob, Louis A1 - Rapp, Michael Armin A1 - Kostev, Karel T1 - Depression risk in patients with coronary heart disease in Germany JF - World Journal of Cardiology N2 - AIM To determine the prevalence of depression and its risk factors among patients with coronary heart disease (CHD) treated in German primary care practices. METHODS Longitudinal data from nationwide general practices in Germany (n = 1072) were analyzed. Individuals initially diagnosed with CHD (2009-2013) were identified, and 59992 patients were included and matched (1: 1) to 59992 controls. The primary outcome measure was an initial diagnosis of depression within five years after the index date among patients with and without CHD. Cox proportional hazards models were used to adjust for confounders. RESULTS Mean age was equal to 68.0 years (SD = 11.3). A total of 55.9% of patients were men. After a five-year follow-up, 21.8% of the CHD group and 14.2% of the control group were diagnosed with depression (P < 0.001). In the multivariate regression model, CHD was a strong risk factor for developing depression (HR = 1.54, 95% CI: 1.49-1.59, P < 0.001). Prior depressive episodes, dementia, and eight other chronic conditions were associated with a higher risk of developing depression. Interestingly, older patients and women were also more likely to be diagnosed with depression compared with younger patients and men, respectively. CONCLUSION The risk of depression is significantly increased among patients with CHD compared with patients without CHD treated in primary care practices in Germany. CHD patients should be routinely screened for depression to ensure improved treatment and management. KW - Coronary heart disease KW - Depression KW - Primary care KW - Risk factors KW - Quality of life Y1 - 2016 U6 - https://doi.org/10.4330/wjc.v8.i9.547 SN - 1949-8462 VL - 8 SP - 547 EP - 552 PB - Baishideng Publishing Group CY - Pleasanton ER - TY - JOUR A1 - Kiefer, Thomas A1 - Krahl, Dorothea A1 - Hirt, Carsten A1 - Völler, Heinz A1 - Voelkel, Lorenz A1 - Daeschlein, Georg T1 - Influence of treatment caused impairments on anxiety and depression in patients with cancer of the Esophagus or the Esophagogastric junction JF - Journal of gastrointestinal cancer N2 - Purpose After therapy of cancer of the esophagus or the esophagogastric junction, patients often suffer from anxiety and depression. Some risk factors for elevated anxiety and depression are reported, but the influence of steatorrhea, the frequency of which has only recently been reported, has not yet been investigated. Method Using the Hospital Anxiety and Depression Scale (HADS), we analyzed the correlation of anxiety and depression with steatorrhea, appetite, and weight loss in 72 patients with cancer of the esophagus or of the esophagogastric junction, who were treated at our rehabilitation clinic between January 2011 and December 2014. In addition, effectiveness of psychological interviews was analyzed. Results We have evaluable anxiety questionnaires from 51 patients showing a median anxiety value of 5 (range 0-13). As for the depression, results from evaluable questionnaires of 54 patients also showed a median value of 5 (range 0-15). Increased anxiety and depression values (> 7) were observed in 25.4% and 37.0% of the patients respectively. Patients who were admitted with steatorrhea for rehabilitation showed a statistically higher anxiety value (median 6.3 vs. 4.7, p < 0.05), reduced appetite, and a weight loss above 15 kg depicting a correlation to anxiety and depression. Psychological conversations helped lowering the depression but had no influence on anxiety. Conclusions Impairments after cancer treatment, such as steatorrhea, appetite loss, and weight loss, should be interpreted as an alarm signal and should necessitate screening for increased anxiety and depression. Psychological therapy can help improving the extent of the depression. KW - Anxiety KW - Depression KW - Esophagus carcinoma KW - Exocrine pancreas KW - insufficiency KW - Rehabilitation KW - Steatorrhea Y1 - 2019 U6 - https://doi.org/10.1007/s12029-018-00193-7 SN - 1941-6628 SN - 1941-6636 VL - 51 IS - 1 SP - 30 EP - 34 PB - Springer CY - New York ER - TY - JOUR A1 - Heißel, Andreas A1 - Bollmann, Julian A1 - Kangas, Maria A1 - Abdulla, K A1 - Rapp, Michael Armin A1 - Sánchez Fernàndez, Alba Cristina T1 - Validation of the German version of the work and social adjustment scale in a sample of depressed patients JF - BMC health services research N2 - Background Depression is one of the key factors contributing to difficulties in one’s ability to work, and serves as one of the major reasons why employees apply for psychotherapy and receive insurance subsidization of treatments. Hence, an increasing and growing number of studies rely on workability assessment scales as their primary outcome measure. The Work and Social Assessment Scale (WSAS) has been documented as one of the most psychometrically reliable and valid tools especially developed to assess workability and social functioning in patients with mental health problems. Yet, the application of the WSAS in Germany has been limited due to the paucity of a valid questionnaire in the German language. The objective of the present study was to translate the WSAS, as a brief and easy administrable tool into German and test its psychometric properties in a sample of adults with depression. Methods Two hundred seventy-seven patients (M = 48.3 years, SD = 11.1) with mild to moderately severe depression were recruited. A multistep translation from English into the German language was performed and the factorial validity, criterion validity, convergent validity, discriminant validity, internal consistency, and floor and ceiling effects were examined. Results The confirmatory factor analysis results confirmed the one-factor structure of the WSAS. Significant correlations with the WHODAS 2–0 questionnaire, a measure of functionality, demonstrated good convergent validity. Significant correlations with depression and quality of life demonstrated good criterion validity. The WSAS also demonstrated strong internal consistency (α = .89), and the absence of floor and ceiling effects indicated good sensitivity of the instrument. Conclusions The results of the present study demonstrated that the German version of the WSAS has good psychometric properties comparable to other international versions of this scale. The findings recommend a global assessment of psychosocial functioning with the sum score of the WSAS. KW - Workability KW - Social functioning KW - Depression KW - Psychometric evaluation KW - Translation Y1 - 2021 U6 - https://doi.org/10.1186/s12913-021-06622-x SN - 1472-6963 VL - 21 SP - 1 EP - 11 PB - BioMed Central CY - London ER - TY - GEN A1 - Heißel, Andreas A1 - Bollmann, J A1 - Kangas, Maria A1 - Rapp, Michael Armin A1 - Sánchez, Alba Cristina A1 - Abdulla, K T1 - Validation of the German version of the work and social adjustment scale in a sample of depressed patients T2 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe N2 - Background Depression is one of the key factors contributing to difficulties in one’s ability to work, and serves as one of the major reasons why employees apply for psychotherapy and receive insurance subsidization of treatments. Hence, an increasing and growing number of studies rely on workability assessment scales as their primary outcome measure. The Work and Social Assessment Scale (WSAS) has been documented as one of the most psychometrically reliable and valid tools especially developed to assess workability and social functioning in patients with mental health problems. Yet, the application of the WSAS in Germany has been limited due to the paucity of a valid questionnaire in the German language. The objective of the present study was to translate the WSAS, as a brief and easy administrable tool into German and test its psychometric properties in a sample of adults with depression. Methods Two hundred seventy-seven patients (M = 48.3 years, SD = 11.1) with mild to moderately severe depression were recruited. A multistep translation from English into the German language was performed and the factorial validity, criterion validity, convergent validity, discriminant validity, internal consistency, and floor and ceiling effects were examined. Results The confirmatory factor analysis results confirmed the one-factor structure of the WSAS. Significant correlations with the WHODAS 2–0 questionnaire, a measure of functionality, demonstrated good convergent validity. Significant correlations with depression and quality of life demonstrated good criterion validity. The WSAS also demonstrated strong internal consistency (α = .89), and the absence of floor and ceiling effects indicated good sensitivity of the instrument. Conclusions The results of the present study demonstrated that the German version of the WSAS has good psychometric properties comparable to other international versions of this scale. The findings recommend a global assessment of psychosocial functioning with the sum score of the WSAS. T3 - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 756 KW - Workability KW - Social functioning KW - Depression KW - Psychometric evaluation KW - Translation Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-547810 SN - 1866-8364 SP - 1 EP - 11 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Heissel, Andreas A1 - Zech, Philipp A1 - Rapp, Michael Armin A1 - Schuch, Felipe B. A1 - Lawrence, Jimmy B. A1 - Kangas, Maria A1 - Heinzel, Stephan T1 - Effects of exercise on depression and anxiety in persons living with HIV: A meta-analysis JF - Journal of psychosomatic research N2 - Objective: The purpose of this systematic review and meta-analysis was to examine the effects of exercise on depression and anxiety in people living with HIV (PLWH), and to evaluate, through subgroup analysis, the effects of exercise type, frequency, supervision by exercise professionals, study quality, and control group conditions on these outcomes. Method: A literature search was conducted through four electronic databases from inception to February 2019. Considered for inclusion were randomized controlled trials (RCTs) investigating exercise interventions and depression or anxiety as outcomes in people living with HIV (>= 18 years of age). Ten studies were included (n = 479 participants, 49.67% females at baseline), and the standardized mean difference (SMD) and heterogeneity were calculated using random-effect models. An additional pre-post meta-analysis was also conducted. Results: A large effect in favor of exercise when compared to controls was found for depression (SMD = -0.84, 95%CI = [-1.57, -0.11], p = 0.02) and anxiety (SMD = -1.23, 95%CI = [-2.42, 0.04], p = -0.04). Subgroup analyses for depression revealed large effects on depression for aerobic exercise only (SMD = -0.96, 95%CI = [-1.63, -0.30], p = 0.004), a frequency of >= 3 exercise sessions per week (SMD = -1.39, 95%CI = [-2.24, -0.54], p < 0.001), professionally supervised exercise (SMD = -1.40, 95%CI = [-2.46, -0.17], p = 0.03]), and high-quality studies (SMD = -1.31, 95%CI = [-2.46, -0.17], p = 0.02). Conclusion: Exercise seems to decrease depressive symptoms and anxiety in PLWH, but other larger and high-quality studies are needed to verify these effects. KW - HIV KW - Exercise KW - Depression KW - Anxiety KW - Meta-analysis KW - Supervision Y1 - 2019 U6 - https://doi.org/10.1016/j.jpsychores.2019.109823 SN - 0022-3999 SN - 1879-1360 VL - 126 PB - Elsevier CY - Oxford ER - TY - THES A1 - Gschwendt, Miriam A. T1 - Early manifestations of aggression in infants of high risk mother-infant dyads N2 - Ziel dieser Untersuchung war es frühe Risikofaktoren von aggressivem Verhalten bei Kleinkindern in einer Stichprobe von Teenager-Müttern und ihren Babys aus sozial schwachen Verhältnissen (high risk sample) zu identifizieren. In den zurückliegenden zwei Jahrzehnten haben Wissenschaftler immer wieder auf die Bedeutung von Strategien hingewiesen, die es ermöglichen, Kinder und Babys mit einem Risiko für aggresives Verhalten zu identifiezieren. Eine frühe Identifizierung ist besonders wichtig, weil schon Babys und Kinder eine signifikante Psychopathologie besitzen können und u. U. von einer Behandlung profitieren. Außerdem postulieren einige Entwicklungstheorien, dass der Ursprung einer späteren Psychopathologie schon in Verhaltensmustern in den ersten Lebensjahren erkannt werden kann. Dies scheint insbesondere für aggressives Verhalten zu gelten. Deshalb besteht grosses Interesse daran, relevante Faktoren in der frühen Kindheit zu identifizieren, die es erlauben aggressives Verhalten im weiteren Verlauf der Kindheit vorauszusagen. Methodik 60 Teenager-Mütter im Alter zwischen 14 und 20 Jahre und ihre Kleinkinder im Alter zwischen 12 und 17 Monaten aus sozial schwachen Verhältnissen wurden untersucht (high risk sample). Die Teenager-Mütter füllten Fragebögen über ihre Kleinkinder (The Infant-Toddler Social and Emotional Assessment [ITSEA], Carter & Briggs-Gowan, 1993) und über sich selber aus (The Parenting Stress Index [PSI], Abidin, 1990, The Symptom CheckList-90-Revised [SCL-90-R], Derogatis, 1986, The Demographic Qüstionnaire, Zelenko et al., in press). Die Kleinkinder nahmen weiters an zwei objektiven Laboruntersuchungen teil (The Strange Situation Procedure, [SS], Ainsworth, 1978, The Bayley Scales of Infant Development Assessment, [BSID-II], Bayley, 1993). Die Studie untersuchte folgende Beziehungen: (1) Psychosoziale Funktionen der Mutter mit berichteter (berichet von Mutter anhand des ITSEA) und beobachteter Aggression und negativer Emotionalität bei Kleinkindern (beobachtet während des BSID-II und SS), (2) berichtete Aggression und negative Emotionalität mit beobachteter Aggression und negative Emotionalität bei Kleinkindern, (3) negative Emotionalität mit Aggression bei Kleinkindern, (4) Emotionsregulation mit Aggression und negativer Emotionalität bei Kleinkindern, und (5) eine mögliche Interaktion zwischen Emotionsregulation und negativer Emotionalität in Beziehung zu Aggression bei Kleinkindern. Zusätzlich wurde die Frage untersucht, ob Geschlecht einen Einfluss hat auf die oben genannten fünf Beziehungen. Ergebnisse Mütter mit höheren Depressionenswerten und Stresswerten berichteten signifikant mehr negative Emotionalität und tendenziell mehr Aggressionen bei ihren Kleinkindern als Mütter mit niedrigeren Depressionswerten und Stresswerten. Keine signifikanten Beziehungen konnten festgestellt werden zwischen Depressionswerten und Stresswerten der Mutter und objektiv beobachteten Aggressionen und negativer Emotionalität bei Kleinkindern. Die Beziehung zwischen beobachteter und berichteter negativer Emotionalität bei Kleinkindern war schwach signifikant. Keine signifikante Beziehung konnte jedoch zwischen beobachteter und berichteter Aggression bei Kleinkindern gezeigt werden. Sowohl berichtete als auch beobachtete negative Emotionalität korrelierte signifikant mit berichteter und beobachteter Aggression bei Kleinkindern. Eine signifikante Beziehung zwischen Emotionsregulation und negativer Emotionalität und Aggression bei Kleinkindern konnte aufgezeigt werden. Kleinkinder mit schwacher Emotionsregulation zeigten signifikant mehr negative Emotionalität und Aggressionen als Kleinkinder mit starker Emotionsregulation. Kleinkinder mit hohen negativen Emotionswerten und schwacher Emotionsregulation zeigten signifikant mehr Aggressionen als Kleinkinder mit hohen negativen Emotionswerten und starker Emotionsregulation und Kleinkindern mit niedrigen negativen Emotionswerten und schwacher oder starker Emotionsregulation. Das Geschlecht des Kleinkindes hatte einen signifikanten Einfluss auf folgende Beziehungen: Mütter mit höheren Depressionswerten und Stresswerten berichteten signifikant mehr Aggressionen und negative Emotionalität bei ihren Töchtern, jedoch nicht signifikant mehr Aggressionen und negative Emotionalität bei ihren Söhnen als Mütter mit niedrigeren Depressionswerten und Stresswerten. Das Geschlecht des Kleinkindes hatte keinen signifikanten Einfluss auf die Beziehung zwischen Depressionswerten und Stresswerten der Mutter und beobachteter Aggression und negativer Emotionalität bei Kleinkindern. Ein interessantes Ergebnis ergab sich hinsichtlich Geschlecht und Emotionsregulationsverhaltensweisen. Buben mit höheren Aggressionswerten schauten signifikant weniger zu ihrer Mutter und signifikant weniger in die Umgebung als Buben mit niedrigeren Aggressionswerten. Mädchen mit höheren Aggressionswerten schauten signifikant mehr zu ihrer Mutter, signifikant mehr in die Umgebung und signifikant mehr auf Spielzeuge als Mädchen mit niedrigen Aggressionswerten. Schlussfolgerung Die Ergebnisse der Untersuchung haben Implikationen für die Einschätzung und die Behandlung von Aggressionen bei Kleinkindern. Erstens, die Ergebnisse weisen darauf hin, dass es unter Umständen wichtig sein könnte verschiedene Messverfahren (Mutter Report und objektive Messverfahren) zu verwenden, um Kleinkinder zu diagnostizieren, die ein erhöhtes Risiko aufweisen im Laufe ihres Lebens Aggressionen zu entwickeln. Zweitens, Ergebnisse identifizierten mütterliche negative Attributionen als einen möglichen Risikofaktor für späteres Aggressionsverhalten bei Kindern. Zukünftige Studien sollten die Beziehung zwischen Aggressionsverhalten im Kleinkindalter und Aggressionen im späteren Leben untersuchen. Ein weiteres interessantes Ergebnis ergab sich hinsichtlich Emotionsregulation. Kleinkinder mit hoher negativer Emotionalität und schwacher Emotionsregualtion zeigten die meisten Aggressionen. Für die Behandlung und die zukünftige Erforschung von Kleinkindaggressionen sollten die drei Konstrukte (Emotionsregualtion, negative Emotionalität und Aggression) miteinander kombiniert werden und nicht alleine untersucht werden. N2 - The primary focus on the present study was to identify early risk factors for infant aggression in a sample of high risk, low-income teenager mothers and their infants. Despite the amount of research on externalizing behavior, relatively little is known about its development in early childhood. Because chronically aggressive school-age children tend to be those who first display symptoms during preschool years, an examination of the early manifestations of aggressive behavior and the development of measurements for infants is needed. The present study explored a model of infant aggression development that emphasized infant aggression developing largely through the interaction of infant′s dispositional characteristics with their caregiving environment. The study addressed the following relations: (1) Maternal psychosocial functioning with reported and observed infant aggression and negative emotionality, (2) reported measurements of infant aggression and negative emotionality with observed infant measurements of infant aggression and negative emotionality, (3) infant negative emotionality and infant aggression, (4) infant emotion regulation with infant aggression and negative emotionality, (5) the interaction between emotion regulation and negative emotionality in relation to infant aggression, and (6) attachment classification with infant aggression and negative emotionality. Finally, the question of whether these six relations would differ by gender was also addressed. Maternal psychosocial functioning was assessed with self-reported measurements. Infant aggression, negative emotionality and emotion regulation were measured during two standardized assessments, the Strange Situation and the Bayley Scales of Infant Development Assessment and maternal reported with the Infant-Toddler Social and Emotional Assessment. Several interesting findings emerged. One of the main findings concerned maternal attribution and its possible role as a risk factor for later externalizing behaviors. That is, mothers, especially depressed and stressed mothers, tended to report higher levels of infant aggression and negative emotionality than was noted by more objective observers. This tendency was particularly evident in mothers with girl infants. Another important finding concerned emotion regulation. Even at this early age, clear differences in emotion regulation could be seen. Interestingly, infants with high negative emotionality and low emotion regulation were observed to be the most aggressive. Also significant relations emerged for infant negative emotionality and aggression and vise versa. Thus, for purposes of treatment and scientific study, the three constructs (emotion regulation, negative emotionality, and aggression) should be considered in combination. Investigating each alone may not prove fruitful in future examinations. Additionally, different emotion regulation behaviors were observed for girl and boy infants. Aggressive girls looked more at the environment, their toys and their mother, whereas aggressive boys looked less at the environment and their mother and explored their toys more, although looked at the toys less. Although difficult to interpret at this point, it is nonetheless interesting that gender differences exist at this young age in emotion regulatory behaviors. In conclusion, although preliminary, findings from the present study provide intriguing directions for future research. More studies need to conducted focusing on infant aggression, as well as longitudinal studies following the infants over time. KW - Junge Mutter / Kind / Aggressivität / Risikoverhalten KW - Aggression KW - Emotionsregulation KW - Negative Emotionalität KW - Kleinkinder KW - Mutter-Kind Interaktion KW - Depression KW - Aggression KW - Emotion Regulation KW - Negative Emotionality KW - Infants KW - Mother-Child Interaction KW - Depression Y1 - 2002 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-0000528 ER - TY - JOUR A1 - Frodl, Thomas A1 - Janowitz, Deborah A1 - Schmaal, Lianne A1 - Tozzi, Leonardo A1 - Dobrowolny, Henrik A1 - Stein, Dan J. A1 - Veltman, Dick J. A1 - Wittfeld, Katharina A1 - van Erp, Theo G. M. A1 - Jahanshad, Neda A1 - Block, Andrea A1 - Hegenscheid, Katrin A1 - Voelzke, Henry A1 - Lagopoulos, Jim A1 - Hatton, Sean N. A1 - Hickie, Ian B. A1 - Frey, Eva Maria A1 - Carballedo, Angela A1 - Brooks, Samantha J. A1 - Vuletic, Daniella A1 - Uhlmann, Anne A1 - Veer, Ilya M. A1 - Walter, Henrik A1 - Schnell, Knut A1 - Grotegerd, Dominik A1 - Arolt, Volker A1 - Kugel, Harald A1 - Schramm, Elisabeth A1 - Konrad, Carsten A1 - Zurowski, Bartosz A1 - Baune, Bernhard T. A1 - van der Wee, Nic J. A. A1 - van Tol, Marie-Jose A1 - Penninx, Brenda W. J. H. A1 - Thompson, Paul M. A1 - Hibar, Derrek P. A1 - Dannlowski, Udo A1 - Grabe, Hans J. T1 - Childhood adversity impacts on brain subcortical structures relevant to depression JF - Journal of psychiatric research N2 - Childhood adversity plays an important role for development of major depressive disorder (MDD). There are differences in subcortical brain structures between patients with MDD and healthy controls, but the specific impact of childhood adversity on such structures in MDD remains unclear. Thus, aim of the present study was to investigate whether childhood adversity is associated with subcortical volumes and how it interacts with a diagnosis of MDD and sex. Within the ENIGMA-MDD network, nine university partner sites, which assessed childhood adversity and magnetic resonance imaging in patients with MDD and controls, took part in the current joint mega-analysis. In this largest effort world-wide to identify subcortical brain structure differences related to childhood adversity, 3036 participants were analyzed for subcortical brain volumes using FreeSurfer. A significant interaction was evident between childhood adversity, MDD diagnosis, sex, and region. Increased exposure to childhood adversity was associated with smaller caudate volumes in females independent of MDD. All subcategories of childhood adversity were negatively associated with caudate volumes in females - in particular emotional neglect and physical neglect (independently from age, ICV, imaging site and MDD diagnosis). There was no interaction effect between childhood adversity and MDD diagnosis on subcortical brain volumes. Childhood adversity is one of the contributors to brain structural abnormalities. It is associated with subcortical brain abnormalities that are relevant to psychiatric disorders such as depression. (C) 2016 Published by Elsevier Ltd. KW - Depression KW - Childhood adversity KW - MRI KW - Caudate KW - Hippocampus KW - ENIGMA Y1 - 2016 U6 - https://doi.org/10.1016/j.jpsychires.2016.11.010 SN - 0022-3956 SN - 1879-1379 VL - 86 SP - 58 EP - 65 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Drosselmeyer, Julia A1 - Jacob, Louis A1 - Rathmann, Wolfgang A1 - Rapp, Michael Armin A1 - Kostev, Karel T1 - Depression risk in patients with late-onset rheumatoid arthritis in Germany JF - Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation N2 - The goal of this study was to determine the prevalence of depression and its risk factors in patients with late-onset rheumatoid arthritis (RA) treated in German primary care practices. Longitudinal data from general practices (n=1072) throughout Germany were analyzed. Individuals initially diagnosed with RA (2009-2013) were identified, and 7301 patients were included and matched (1:1) to 7301 controls. The primary outcome measure was the initial diagnosis of depression within 5 years after the index date in patients with and without RA. Cox proportional hazards models were used to adjust for confounders. The mean age was 72.2 years (SD: 7.6 years). A total of 34.9 % of patients were men. Depression diagnoses were present in 22.0 % of the RA group and 14.3 % of the control group after a 5-year follow-up period (p < 0.001). In the multivariate regression model, RA was a strong risk factor for the development of depression (HR: 1.55, p < 0.001). There was significant interaction of RA and diagnosed inflammatory polyarthropathies (IP) (RA*IP interaction: p < 0.001). Furthermore, dementia, cancer, osteoporosis, hypertension, and diabetes were associated with a higher risk of developing depression (p values < 0.001). The risk of depression is significantly higher in patients with late-onset RA than in patients without RA for subjects treated in primary care practices in Germany. RA patients should be screened routinely for depression in order to ensure improved treatment and management. KW - Late-onset rheumatoid arthritis KW - Depression KW - Primary care KW - Risk factors KW - Germany Y1 - 2016 U6 - https://doi.org/10.1007/s11136-016-1387-2 SN - 0962-9343 SN - 1573-2649 VL - 26 IS - 2 SP - 437 EP - 443 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Buchmann, Arlette F. A1 - Hellweg, Rainer A1 - Rietschel, Marcella A1 - Treutlein, Jens A1 - Witt, Stephanie H. A1 - Zimmermann, Ulrich S. A1 - Schmidt, Martin H. A1 - Esser, Günter A1 - Banaschewski, Tobias A1 - Laucht, Manfred A1 - Deuschle, Michael T1 - BDNF Val 66 Met and 5-HTTLPR genotype moderate the impact of early psychosocial adversity on plasma brain-derived neurotrophic factor and depressive symptoms - a prospective study JF - European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology N2 - Recent studies have emphasized an important role for neurotrophins, such as brain-derived neurotrophic factor (BDNF), in regulating the plasticity of neural circuits involved in the pathophysiology of stress-related diseases. The aim of the present study was to examine the interplay of the BDNF Val(66)Met and the serotonin transporter promoter (5-HTTLPR) polymorphisms in moderating the impact of early-life adversity on BDNF plasma concentration and depressive symptoms. Participants were taken from an epidemiological cohort study following the long-term outcome of early risk factors from birth into young adulthood. In 259 individuals (119 males, 140 females), genotyped for the BDNF Val(66)Met and the 5-HTTLPR polymorphisms, plasma BDNF was assessed at the age of 19 years. In addition, participants completed the Beck Depression Inventory (BDI). Early adversity was determined according to a family adversity index assessed at 3 months of age. Results indicated that individuals homozygous for both the BDNF Val and the 5-HTTLPR L allele showed significantly reduced BDNF levels following exposure to high adversity. In contrast, BDNF levels appeared to be unaffected by early psychosocial adversity in carriers of the BDNF Met or the 5-HTTLPR S allele. While the former group appeared to be most susceptible to depressive symptoms, the impact of early adversity was less pronounced in the latter group. This is the first preliminary evidence indicating that early-life adverse experiences may have lasting sequelae for plasma BDNF levels in humans, highlighting that the susceptibility to this effect is moderated by BDNF Val(66)Met and 5-HTTLPR genotype. KW - BDNF KW - 5-HTTLPR KW - Human KW - Early psychosocial adversity KW - Longitudinal study KW - Depression Y1 - 2013 U6 - https://doi.org/10.1016/j.euroneuro.2012.09.003 SN - 0924-977X VL - 23 IS - 8 SP - 902 EP - 909 PB - Elsevier CY - Amsterdam ER - TY - THES A1 - Berding, Anja T1 - Kurz-, mittel- und langfristige Effekte einer Schulung für Patienten mit chronisch entzündlichen Darmerkrankungen auf krankheitsbezogene Ängste und Gesundheitskompetenzen T1 - Beneficial short-, medium-, and long-term effects of education on disease-related worries and concerns and health competencies in patients with inflammatory bowel diseases N2 - Menschen mit chronisch entzündlichen Darmerkrankungen (CED) leiden unter vielfältigen körperlichen und psychosozialen Einschränkungen. Wie auch bei anderen chronischen Erkrankungen könnten Patientenschulungen ihr psychisches Befinden verbessern (z.B. De Ridder & Schreurs, 2001; Faller, Reusch & Meng, 2011a; Küver, Becker & Ludt, 2008; Schüssler, 1998; Warsi, Wang, LaValley, Avorn & Solomon, 2004). Für CED liegen jedoch nur wenige Schulungsevaluationen vor (z.B. Bregenzer et al., 2005; Mussell, Böcker, Nagel, Olbrich & Singer, 2003; Oxelmark, Magnusson, Löfberg & Hillerås, 2007), deren Aussagekraft i.d.R. durch methodische Mängel eingeschränkt ist. Daher ist die Bedeutung von Schulungsprogrammen für CED-Betroffene weiterhin offen. Überdies gibt es für den deutschen Sprachraum noch keine Schulung, die zu psychischen Verbesserungen führt. Aus diesem Grunde wurde ein 1,5-tägiges Wochenend-Seminar mit medizinischen und psychologischen Inhalten konzeptionalisiert, manualisiert und in der vorliegenden Studie evaluiert. Zur summativen Evaluation nahmen 181 ambulante CED-Patienten an einer prospektiven, multizentrischen, randomisierten, kontrollierten Studie mit vier Messzeitpunkten teil: vor (T1), zwei Wochen (T2) und drei Monate (T3) nach dem Seminar. Zur 12-Monatskatamnese (T4EG) wurde die Stabilität der Effekte in der Experimentalgruppe (EG; n = 86) überprüft. Die Wartekontrollgruppe (n = 95) erhielt zunächst die Standardbehandlung, also keine Patientenschulung, und konnte an dieser nach der dritten Datenerhebung ebenfalls teilnehmen. Kovarianzanalysen (ANCOVAs) mit Kontrolle für die jeweilige Ausgangslage wurden durchgeführt. Weitere Analysen legten eine Adjustierung für die Krankheitsaktivität zu T1 nahe, weshalb diese als zusätzliche Kovariate in die ANCOVAs aufgenommen wurde. Krankheitsbezogene Ängste und Sorgen (PS-CEDE Gesamtwert zu T3; Krebs, Kachel & Faller, 1998) fungierten als primärer Zielparameter. Zu den sekundären Zielkriterien gehörten Progredienzangst und Angstbewältigung (PA-F-KF und PA-F; Mehnert, Herschbach, Berg, Henrich & Koch, 2006 bzw. Dankert et al., 2003; Herschbach et al., 2005) sowie die Gesundheitskompetenzen Positive Grundhaltung, Aktive Lebensgestaltung und Erwerb von Fertigkeiten und Handlungsstrategien (heiQ; Osborne, Elsworth & Whitfield, 2007; Schuler et al., 2013). Weitere sekundäre Zielparameter waren gesundheitsbezogene Lebensqualität (SF-12; Bullinger & Kirchberger, 1998), Symptome einer Angststörung oder Depression (PHQ-4; Kroenke, Spitzer, Williams & Löwe, 2009; Löwe et al., 2010), Wissen, der Umgang mit der CED bzw. von ihr ausgelösten negativen Gefühlen sowie die Zufriedenheit der Teilnehmenden mit dem Seminar. Von Interesse war außerdem, ob Geschlecht, Alter, Art, Dauer oder Aktivität der Erkrankung vor der Schulung einen Einfluss auf die genannten Variablen hatten und ob für sie differentielle Wirksamkeitseffekte bestanden. Darüber hinaus wurden krankheitsbezogene Ängste und Sorgen von ungeschulten Studienteilnehmern untersucht. Zwei Wochen und drei Monate nach der Schulung ließen sich im Vergleich von Experimental- und Kontrollgruppe signifikante, mittlere bis große Effekte auf krankheitsbezogene Ängste und Sorgen, Progredienzangst und deren Bewältigung sowie eine Positive Grundhaltung der CED gegenüber erzielen (stets p ≤ .001). Außerdem kam es zu beiden Messzeitpunkten zu signifikanten, großen Interventionseffekten auf den Erwerb von Fertigkeiten und Handlungsstrategien im Umgang mit der Erkrankung, das Wissen um sie und den Umgang mit ihr (stets p < .001) sowie zu moderaten Effekten auf den Umgang mit CED-bedingten negativen Gefühlen (T2: p = .001; T3: p = .008). Alle beschriebenen Effekte waren auch nach zwölf Monaten noch stabil. Für Aktive Lebensgestaltung, gesundheitsbezogene Lebensqualität sowie Angst- und Depressionssymptomatik konnten keine Schulungseffekte nachgewiesen werden. Die zusätzliche Kontrolle für die Krankheitsaktivität zu T1 führte zu keinen wesentlichen Änderungen in den Ergebnissen. Auch bei den Subgruppenanalysen hatte die Krankheitsaktivität keinen relevanten Einfluss auf die Wirksamkeit der Schulung. Gleiches gilt für Geschlecht, Alter, Art und Dauer der CED. Mit Ausnahme der Krankheitsaktivität deuteten dies bereits die zur Baseline durchgeführten t-Tests an, bei denen insgesamt nur sehr wenige signifikante, höchstens moderate Unterschiede zwischen den einzelnen Subgruppen auftraten. Sowohl bei der formativen als auch der summativen Evaluation zeigte sich überdies die hohe Zufriedenheit der Teilnehmenden mit der Schulung. Neben der Akzeptanz konnte außerdem die Durchführbarkeit bestätigt werden. Die Auswertung der Ängste und Sorgen der Studienteilnehmenden lieferte zudem Hinweise für die Entwicklung und Modifikation von Interventionen für CED-Betroffene. Es lässt sich festhalten, dass für die hier evaluierte Schulung für CED-Patienten ein Wirksamkeitsnachweis erbracht werden konnte und sie sehr positiv von den Teilnehmenden bewertet wurde. Sie führte sowohl kurz-, mittel- als auch langfristig zu substantiellen Verbesserungen in psychischer Belastung, Selbstmanagement-Fähigkeiten, der Bewältigung der Erkrankung sowie im Wissen und war gleichermaßen wirksam bei Betroffenen, die sich in Geschlecht, Alter, Art, Dauer oder Aktivität ihrer CED unterschieden. N2 - People with inflammatory bowel diseases (IBD) are affected by a wide range of somatic and psychosocial impairments. As in other chronic conditions, patient education might improve their well-being (e.g., De Ridder & Schreurs, 2001; Faller et al., 2011a; Küver et al., 2008; Schüssler, 1998; Warsi et al., 2004). In IBD only a few evaluations of education programs are available (e.g., Bregenzer et al., 2005; Mussell et al., 2003; Oxelmark et al., 2007) whose significance is limited due to several methodological flaws. The impact of education in IBD remains therefore unclear. Furthermore, there is no program contributing to psychological improvements for the German-speaking area so far. Thus, a manualized 1.5-day weekend-seminar for IBD patients, addressing medical and psychological issues, was designed. The main aim of this study was to evaluate it in a large controlled trial. For summative evaluation, 181 outpatients participated in a prospective, multicenter, randomized, waitlist-controlled trial with assessments before (t1) as well as two weeks (t2) and three months (t3) after the seminar. Patients serving as waitlist controls (n = 95) received treatment as usual (no patient education) and were also offered to participate in the intervention after the third data collection. The intervention group (IG, n = 86) was reassessed for stability of effects at the 12-months follow-up (t4IG). Analysis of covariance (ANCOVA) with adjustment for the respective baseline score was used. Due to further analyses, which suggested a control for baseline perceived disease activity, the ANCOVAs were repeated with that additional covariate. Disease-related worries and concerns (IBDPC total score at t3, German validation by Krebs et al., 1998; original: RFIPC by Drossman et al., 1991) were the primary outcome. Secondary outcomes included fear of progression and coping with anxiety (FoP-Q-SF; Mehnert et al., 2006; FoP-Q; Dankert et al., 2003; Herschbach et al., 2005), and the following three health competencies: constructive attitudes and approaches, skill and technique acquisition as well as positive and active engagement in life (heiQ; Osborne et al., 2007; Schuler et al., 2013). Further sec¬ondary outcomes were health-related quality of life (HRQoL; SF-12; Bullinger & Kirchberger, 1998), symptoms of depression and anxiety (PHQ-4; Kroenke et al., 2009; Löwe et al., 2010), disease-related knowledge, coping, and participants’ satisfaction with the seminar. It was also of interest, if patient characteristics like sex, age, type, duration or activity of IBD influenced those variables at baseline and if differential effects of the intervention existed. Moreover, baseline disease-related worries and concerns were analyzed. At two weeks and three months post-intervention, significant medium to large effects on disease-related worries and concerns, fear of progression, and coping with anxiety as well as constructive attitudes and approaches could be achieved (each p ≤ .001). In addition, large significant effects on skill and technique acquisition, knowledge, and coping with IBD (each p < .001) and medium effects on coping with disease-related negative emotions (t2: p = .001; t3: p = .008) were found. All aforementioned effects persisted even after one year. Effects on positive and active engagement in life, HRQoL as well as symptoms of anxiety and depression could not be observed. Additional adjustment for perceived disease activity basically yielded similar results. Moreover, subgroup analyses did not show any relevant influence of disease activity on the effectiveness of the intervention. The same applies to participants’ sex and age as well as their type of IBD and its duration. With the exception of disease activity, this was already suggested by t-tests performed at baseline, which showed only very few significant differences of moderate size between subgroups. Furthermore, for formative and summative evaluation the education program was rated very favorably by the attendees. In addition to its acceptance, its feasibility was confirmed. The results of the analyses of study participants’ disease-related worries and concerns can be used for the develop¬ment and modification of interventions for patients with IBD. In conclusion, the patient education program tested in this study proved to be effective and was appreciated by the attendees. It contributed to substantial short-, medium-, and even long-term improvements in psychological distress, self-management skills, coping with IBD, and knowledge, which were independent of sex, age, type, duration, or activity of IBD. KW - Patientenschulung KW - chronisch entzündliche Darmerkrankungen KW - Krankheitsbewältigung KW - Lebensqualität KW - Selbstmanagement KW - Ängste und Sorgen KW - Progredienzangst KW - Depression KW - Wissen KW - Coping KW - patient education KW - Morbus Crohn KW - Colitis ulcerosa KW - inflammatory bowel disease KW - Crohn's disease KW - ulcerative colitis KW - coping KW - disease management KW - self-management KW - quality of life KW - worries and concerns KW - fear of progression KW - anxiety KW - depression KW - knowledge Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-401063 ER - TY - CHAP ED - Warschburger, Petra ED - Ihle, Wolfgang ED - Esser, Günter T1 - Seelisch gesund von Anfang an : Programm und Abstracts des 26. Symposiums der Fachgruppe Klinische Psychologie und Psychotherapie der Deutschen Gesellschaft für Psychologie, 1. - 3. Mai 2008 in Potsdam N2 - Der Tagungsband enthält das Programm und die Abstracts des 26. Symposiums der Fachgruppe Klinische Psychologie und Psychotherapie der Deutschen Gesellschaft für Psychologie, veranstaltet an der Universität Potsdam vom 1. bis 3. Mai 2008. Etwa 450 Kongressteilnehmer präsentieren den aktuellen Forschungs- und Wissensstand der Klinischen Psychologie und Psychotherapie in Deutschland. Grußworte halten die brandenburgische Ministerin für Arbeit, Soziales, Gesundheit und Familie, Dagmar Ziegler, die Präsidentin der Universität Potsdam, Prof. Dr.-Ing. Dr. Sabine Kunst, sowie Prof. Dr. Michael Linden als Vertreter der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN). Zu den Themenschwerpunkten des Kongresses gehören Einflussfaktoren auf die psychische Gesundheit Älterer, Impulsivität, Schlaf- und Traumforschung in der Klinischen Psychologie, Behandlung von Essstörungen, Wirksamkeitsstudien psychischer Störungen des Kindes- und Jugendalters, Angst und Depression, Behandlung von Kriegs- und Folteropfern, Risiko- und Schutzfaktoren der Kindesentwicklung sowie Adipositas im Kindes- und Jugendalter. Außer den Vorträgen gibt es eine Präsentation von etwa 150 Postern. Zum Programm der Tagung gehört ebenso die Verleihung des Klaus-Grawe-Awards for the Advancement of Innovative Research in Clinical Psychology and Psychotherapy an Prof. Dr. Timothy J. Strauman von der Duke University (USA), die Verleihung der Nachwuchswissenschaftler- und Posterpreise sowie ein Pre-conference Workshop für Doktorandinnen und Doktoranden der Klinischen Psychologie zum Thema "Verhaltens- und Molekulargenetik". KW - Konferenz KW - Tagung KW - Klinische Psychologie KW - Älterer Mensch / Psychische Gesundheit KW - Kinderpsychologie / Jugendpsychologie / Psychische Störung KW - Symposium KW - Essstörung KW - Adipositas KW - Impulsivität KW - Schlaf- und Traumforschung KW - Angst KW - Depression KW - Kriegsopfer KW - Folteropfer KW - symposium KW - impulsivity KW - eating disorder KW - clinical psychology KW - middle aged / mental health KW - child / adolescent / mental-health problem Y1 - 2008 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-17551 SN - 978-3-940793-34-8 PB - Universitätsverlag Potsdam CY - Potsdam ER -