TY  - JOUR
A1  - Sidiropoulos, Kyriakos
A1  - De Bleser, Ria
A1  - Ablinger, Irene
A1  - Ackermann, Hermann
T1  - The relationship between verbal and nonverbal auditory signal processing in conduction aphasia: behavioral and anatomical evidence for common decoding mechanisms
JF  - Neurocase : the neural basis of cognition
N2  - The processing of nonverbal auditory stimuli has not yet been sufficiently investigated in patients with aphasia. On the basis of a duration discrimination task, we examined whether patients with left-sided cerebrovascular lesions were able to perceive time differences in the scale of approximately 150ms. Further linguistic and memory-related tasks were used to characterize more exactly the relationships in the performances between auditory nonverbal task and selective linguistic or mnemonic disturbances. All examined conduction aphasics showed increased thresholds in the duration discrimination task. The low thresholds on this task were in a strong correlative relation to the reduced performances in repetition and working memory task. This was interpreted as an indication of a pronounced disturbance in integrating auditory verbal information into a long-term window (sampling disturbance) resulting in an additional load of working memory. In order to determine the lesion topography of patients with sampling disturbances, the anatomical and psychophysical data were correlated on the basis of a voxelwise statistical approach. It was found that tissue damage extending through the insula, the posterior superior temporal gyrus, and the supramarginal gyrus causes impairments in sequencing of time-sensitive information.
KW  - brain lesions
KW  - conduction aphasia
KW  - processing of auditory nonverbal stimuli
KW  - speech perception
KW  - speech pathology
KW  - lesion studies
Y1  - 2015
U6  - https://doi.org/10.1080/13554794.2014.902471
SN  - 1355-4794
SN  - 1465-3656
VL  - 21
IS  - 3
SP  - 377
EP  - 393
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  -