TY  - JOUR
A1  - Poxson, David J.
A1  - Karady, Michal
A1  - Gabrielsson, Roger
A1  - Alkattan, Aziz Y.
A1  - Gustavsson, Anna
A1  - Doyle, Siamsa M.
A1  - Robert, Stephanie
A1  - Ljung, Karin
A1  - Grebe, Markus
A1  - Simon, Daniel T.
A1  - Berggren, Magnus
T1  - Regulating plant physiology with organic electronics
JF  - Proceedings of the National Academy of Sciences of the United States of America
N2  - The organic electronic ion pump (OEIP) provides flow-free and accurate delivery of small signaling compounds at high spatio-temporal resolution. To date, the application of OEIPs has been limited to delivery of nonaromatic molecules to mammalian systems, particularly for neuroscience applications. However, many long-standing questions in plant biology remain unanswered due to a lack of technology that precisely delivers plant hormones, based on cyclic alkanes or aromatic structures, to regulate plant physiology. Here, we report the employment of OEIPs for the delivery of the plant hormone auxin to induce differential concentration gradients and modulate plant physiology. We fabricated OEIP devices based on a synthesized dendritic polyelectrolyte that enables electrophoretic transport of aromatic substances. Delivery of auxin to transgenic Arabidopsis thaliana seedlings in vivo was monitored in real time via dynamic fluorescent auxin-response reporters and induced physiological responses in roots. Our results provide a starting point for technologies enabling direct, rapid, and dynamic electronic interaction with the biochemical regulation systems of plants.
KW  - auxin
KW  - Arabidopsis thaliana
KW  - dendritic polymer
KW  - bioelectronics
KW  - polyelectrolyte
Y1  - 2017
U6  - https://doi.org/10.1073/pnas.1617758114
SN  - 0027-8424
VL  - 114
SP  - 4597
EP  - 4602
PB  - National Acad. of Sciences
CY  - Washington
ER  -