TY - JOUR A1 - Wallny, Thomas A. A1 - Brackmann, H. H. A1 - Gunia, Günter A1 - Wilbertz, P. A1 - Oldenburg, J. A1 - Kraft, Clayton. N. T1 - Successful pain treatment in arthropathic lower extremities by acupuncture in haemophilia patients JF - Haemophilia : the official journal of the World Federation of Haemophilia N2 - Acupuncture is successfully used in the treatment of degenerative osteoarthritis. The treatment of haemophilic arthropathies can require strong painkillers with severe side-effects. Therefore, a special yet simple acupuncture technique was evaluated in the treatment of these joint problems. Twelve patients with a factor VIII activity < 1% and at least one painful arthropathy in both lower extremities were included in this single-blinded study. The non-treated side served as a control. Treatment was assessed by a visual analogue scale (VAS) and an orthopaedic clinical examination. Only one needle was inserted at the rear fontanelle once per week and in 15 cycles. Ten of 12 patients showed an improvement of their pain perception. The average VAS could be reduced from 6.8 to 5.0. The side not receiving treatment showed a reduction from 4.1 to 4.0. No side-effects were observed. Even though interpretation of our data are limited due to the small patient numbers, significant improvement of the VAS after treatment suggests that acupuncture has a measurable positive effect in pain management for haemophilic arthropathy of the lower extremities. KW - acupuncture KW - arthropathies KW - haemophilia KW - pain Y1 - 2006 U6 - https://doi.org/10.1111/j.1365-2516.2006.01308.x SN - 1351-8216 VL - 12 IS - 5 SP - 500 EP - 502 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Dornhof, Sarah T1 - Regimes of visibility representing violence against women in the French banlieue JF - Feminist review N2 - Recent discussions about violence against women have shifted their attention to specific forms of violence in relation to migration and Islam. In this article, I consider different modes of representing women's experiences in French immigrant communities. These representations relate to the French feminist movement Ni Putes Ni Soumises (neither whore nor submissive), a movement that in the early 2000s deplored both the sustained degradation of certain banlieue neighborhoods and also the charges and restrictions that this entails, particularly for young women. Drawing on different narratives and images of women's painful experience, I consider, in a first step, how the question of representing violence against (post) migrant women is framed in terms of the tension between universality and particularity within French republicanism. In the next part of my argument, I bring into focus the question of how to access women's suffering. For a perspective on pain not as an interiorized, private experience but as an accessible complex of practices, articulations, memories, visions and social reconfigurations, I consider Smain Laacher's sociological study (2008) about written testimonies of violent experience that had been addressed by (post) migrant women to French women organizations such as Ni Putes Ni Soumises. I finally suggest reading women's accounts on violence not in relation to a universal discourse of rights, but as a political contestation of the naturalized order of representing violence, suffering and agency inside French banlieue communities. Drawing on Jacques Ranciere's notion of dissensus, such a contestation can be staged through words by those who have no visibility in the representational order, words not to criticize the unaccomplished ideals of universal equality, but to create a universal community and a common language of experience in the mode of 'as-if'. KW - visibility KW - pain KW - violence against women KW - dissensus Y1 - 2011 U6 - https://doi.org/10.1057/fr.2011.2 SN - 0141-7789 IS - 98 SP - 110 EP - 127 PB - Palgrave Macmillan CY - Basingstoke ER - TY - JOUR A1 - Bogen, Oliver A1 - Bender, Olaf A1 - Loewe, Jana A1 - Blenau, Wolfgang A1 - Thevis, Beatrice A1 - Schroeder, Wolfgang A1 - Margolis, Richard U. A1 - Levine, Jon D. A1 - Hucho, Ferdinand T1 - Neuronally produced versican V2 renders C-fiber nociceptors IB4-positive JF - Journal of neurochemistry N2 - A subpopulation of nociceptors, the glial cell line-derived neurotrophic factor (GDNF)-dependent, non-peptidergic C-fibers, expresses a cell-surface glycoconjugate that can be selectively labeled with isolectin B4 (IB4), a homotetrameric plant lectin from Griffonia simplicifolia. We show that versican is an IB4-binding molecule in rat dorsal root ganglion neurons. Using reverse transcriptase polymerase chain reaction (RT-PCR), insitu hybridization and immunofluorescence experiments on rat lumbar dorsal root ganglion, we provide the first demonstration that versican is produced by neurons. In addition, by probing Western blots with splice variant-specific antibodies we show that the IB4-binding versican contains only the glycosaminoglycan alpha domain. Our data support V2 as the versican isoform that renders this subpopulation of nociceptors IB4-positive (+). A subset of nociceptors, the GDNF-dependent non-peptidergic C-fibers can be characterized by its reactivity for isolectin B4 (IB4), a plant lectin from Griffonia simplicifolia. We have previously demonstrated that versican V2 binds IB4 in a Ca2+-dependent manner. However, given that versican is thought to be the product of glial cells, it was questionable whether versican V2 can be accountable for the IB4-reactivity of this subset of nociceptors. The results presented here prove - for the first time - a neuronal origin of versican and suggest that versican V2 is the molecule that renders GDNF-dependent non-peptidergic C-fibers IB4-positive. KW - IB4 KW - nociceptors KW - pain KW - sensory neurons KW - V2 KW - versican Y1 - 2015 U6 - https://doi.org/10.1111/jnc.13113 SN - 0022-3042 SN - 1471-4159 VL - 134 IS - 1 SP - 147 EP - 155 PB - Wiley-Blackwell CY - Hoboken ER -