TY  - JOUR
A1  - Chea, Sany
A1  - Nguyen, Khac Toan
A1  - Rosencrantz, Ruben R.
T1  - Microwave-Assisted Synthesis of 5 '-O-methacryloylcytidine Using the Immobilized Lipase Novozym 435
JF  - Molecules
N2  - Nucleobase building blocks have been demonstrated to be strong candidates when it comes to DNA/RNA-like materials by benefiting from hydrogen bond interactions as physical properties. Modifying at the 5 ' position is the simplest way to develop nucleobase-based structures by transesterification using the lipase Novozym 435. Herein, we describe the optimization of the lipase-catalyzed synthesis of the monomer 5 '-O-methacryloylcytidine with the assistance of microwave irradiation. Variable reaction parameters, such as enzyme concentration, molar ratio of the substrate, reaction temperature and reaction time, were investigated to find the optimum reaction condition in terms of obtaining the highest yield.
KW  - microwave irradiation
KW  - Novozym 435
KW  - cytidine
KW  - monomer
KW  - smart materials
Y1  - 2022
U6  - https://doi.org/10.3390/molecules27134112
SN  - 1420-3049
VL  - 27
IS  - 13
PB  - MDPI
CY  - Basel
ER  - 
TY  - GEN
A1  - Laschewsky, André
T1  - Structures and synthesis of zwitterionic polymers
T2  - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe
N2  - The structures and synthesis of polyzwitterions ("polybetaines") are reviewed, emphasizing the literature of the past decade. Particular attention is given to the general challenges faced, and to successful strategies to obtain polymers with a true balance of permanent cationic and anionic groups, thus resulting in an overall zero charge. Also, the progress due to applying new methodologies from general polymer synthesis, such as controlled polymerization methods or the use of "click" chemical reactions is presented. Furthermore, the emerging topic of responsive ("smart") polyzwitterions is addressed. The considerations and critical discussions are illustrated by typical examples.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1043 
KW  - review
KW  - polyzwitterion
KW  - polyampholyte
KW  - zwitterionic group
KW  - betaine
KW  - synthesis
KW  - monomer
KW  - polymerization
KW  - post-polymerization modification
Y1  - 2020
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-476167
SN  - 1866-8372
IS  - 1043
ER  - 
TY  - JOUR
A1  - Laschewsky, André
T1  - Structures and synthesis of zwitterionic polymers
JF  - Polymers
N2  - The structures and synthesis of polyzwitterions ("polybetaines") are reviewed, emphasizing the literature of the past decade. Particular attention is given to the general challenges faced, and to successful strategies to obtain polymers with a true balance of permanent cationic and anionic groups, thus resulting in an overall zero charge. Also, the progress due to applying new methodologies from general polymer synthesis, such as controlled polymerization methods or the use of "click" chemical reactions is presented. Furthermore, the emerging topic of responsive ("smart") polyzwitterions is addressed. The considerations and critical discussions are illustrated by typical examples.
KW  - review
KW  - polyzwitterion
KW  - polyampholyte
KW  - zwitterionic group
KW  - betaine
KW  - synthesis
KW  - monomer
KW  - polymerization
KW  - post-polymerization modification
Y1  - 2014
U6  - https://doi.org/10.3390/polym6051544
SN  - 2073-4360
VL  - 6
IS  - 5
SP  - 1544
EP  - 1601
PB  - MDPI
CY  - Basel
ER  -