TY  - JOUR
A1  - Fritzsch, Claire
A1  - Wang, Jing
A1  - dos Santos, Luara Ferreira
A1  - Mauritz, Karl-Heinz
A1  - Brunetti, Maddalena
A1  - Dohle, Christian
T1  - Different effects of the mirror illusion on motor and somatosensory processing
JF  - Restorative neurology and neuroscience
N2  - Purpose: Mirror therapy can improve motor and sensory functions, but effects of the mirror illusion on primary motor and somatosensory cortex could not be established consistently.
 Methods: Fifteen right handed healthy volunteers performed or observed a finger-thumb opposition task. Cerebral activations during normal movement (NOR), mirrored movement (MIR) and movement observation (OBS) by means of a video chain were recorded with functional magnetic resonance imaging (fMRI). Activation sizes in movement > static conditions were identified using SPM8 (p < 0.001, unc.) and attributed to predefined areas employing the Anatomy toolbox 1.8. Laterality indices for the responsive areas were calculated on the basis of the number of activated voxels.
 Results: Relevant bilateral BOLD responses were found in primary motor (M1) and somatosensory (S1 - BA 2, 3b and 3a) cortex, premotor and parietal areas and V5. When comparing MIR to NOR, no significant change of contralateral activation in M1 was found, but clearly at S1 with differences between hands.
 Conclusion: The mirror illusion does not elicit immediate changes in motor areas, yet there is a direct effect on somatosensory areas, especially for left hand movements. These results suggest different effects of mirror therapy on processing and rehabilitation of motor and sensory function.
KW  - Movement
KW  - mirror
KW  - laterality
KW  - stroke
KW  - sensorimotor cortex
Y1  - 2014
U6  - https://doi.org/10.3233/RNN-130343
SN  - 0922-6028
SN  - 1878-3627
VL  - 32
IS  - 2
SP  - 269
EP  - 280
PB  - IOS Press
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wang, Jing
A1  - Fritzsch, Claire
A1  - Bernarding, Johannes
A1  - Holtze, Susanne
A1  - Mauritz, Karl-Heinz
A1  - Brunetti, Maddalena
A1  - Dohle, Christian
T1  - A comparison of neural mechanisms in mirror therapy and movement observation therapy
JF  - Journal of rehabilitation medicine : official journal of the UEMS European Board of Physical and Rehabilitation Medicine
N2  - Objective: To compare lateralized cerebral activations elicited during self-initiated movement mirroring and observation of movements.
 Subjects: A total of 15 right-handed healthy subjects, age range 22-56 years.
 Methods: Functional imaging study comparing movement mirroring with movement observation, in both hands, in an otherwise identical setting. Imaging data were analysed using statistical parametric mapping software, with significance threshold set at p<0.01 (false discovery rate) and a minimum cluster size of 20 voxels.
 Results: Movement mirroring induced additional activation in primary and higher-order visual areas strictly contralateral to the limb seen by the subject. There was no significant difference of brain activity when comparing movement observation of somebody else's right hand with left hand.
 Conclusion: Lateralized cerebral activations are elicited by inversion of visual feedback (movement mirroring), but not by movement observation.
KW  - fMRI
KW  - mirror
KW  - movement
KW  - observation
KW  - precuneus
Y1  - 2013
U6  - https://doi.org/10.2340/16501977-1127
SN  - 1650-1977
VL  - 45
IS  - 4
SP  - 410
EP  - 413
PB  - Foundation for Rehabilitation Information
CY  - Uppsala
ER  -