47411
2020
2020
eng
13
11
article
Frontiers Research Foundation
Lausanne
1
2020-07-09
2020-03-10
--
Transcutaneous Vagus Nerve Stimulation (tVNS) Improves High-Confidence Recognition Memory but Not Emotional Word Processing
Previous clinical research found that invasive vagus nerve stimulation (VNS) enhanced word recognition memory in epileptic patients, an effect assumed to be related to the activation of brainstem arousal systems. In this study, we applied non-invasive transcutaneous auricular VNS (tVNS) to replicate and extend the previous work. Using a single-blind, randomized, between-subject design, 60 healthy volunteers received active or sham stimulation during a lexical decision task, in which emotional and neutral stimuli were classified as words or non-words. In a subsequent recognition memory task (1 day after stimulation), participants' memory performance on these words and their subjective memory confidence were tested. Salivary alpha-amylase (sAA) levels, a putative indirect measure of central noradrenergic activation, were also measured before and after stimulation. During encoding, pleasant words were more accurately detected than neutral and unpleasant words. However, no tVNS effects were observed on task performance or on overall sAA level changes. tVNS also did not modulate overall recognition memory, which was particularly enhanced for pleasant emotional words. However, when hit rates were split based on confidence ratings reflecting familiarity- and recollection-based memory, higher recollection-based memory performance (irrespective of emotional category) was observed during active stimulation than during sham stimulation. To summarize, we replicated prior findings of enhanced processing and memory for emotional (pleasant) words. Whereas tVNS showed no effects on word processing, subtle effects on recollection-based memory performance emerged, which may indicate that tVNS facilitates hippocampus-mediated consolidation processes.
Frontiers in Psychology
10.3389/fpsyg.2020.01276
1664-1078
1276
<a href="https://doi.org/10.25932/publishup-47412">Zweitveröffentlichung in der Schriftenreihe Postprints der Universität Potsdam : Humanwissenschaftliche Reihe ; 649</a>
Universität Potsdam
PA 2020_056
1998.33
CC-BY - Namensnennung 4.0 International
Manon Giraudier
Carlos Ventura-Bort
Mathias Weymar
eng
uncontrolled
transcutaneous vagus nerve stimulation
eng
uncontrolled
salivary alpha-amylase
eng
uncontrolled
emotion
eng
uncontrolled
words
eng
uncontrolled
episodic memory
eng
uncontrolled
recognition
eng
uncontrolled
recollection
eng
uncontrolled
confidence
Psychologie
Strukturbereich Kognitionswissenschaften
Referiert
Publikationsfonds der Universität Potsdam
Gold Open-Access
56921
2020
2020
eng
S73
S73
1
57
article
Wiley-Blackwell
Malden
1
2020-11-04
2020-11-04
--
Effects of transcutaneous vagus nerve stimulation (TVNS) on emotional word processing and recognition memory
Psychophysiology
0048-5772
1469-8986
wos:2020
Virtual Annual Meeting of the Society-for-Psychophysiological-Research<br /> (SPR)
OCT 04-11, 2020
WOS:000578448200280
ELECTR NETWORK
manon.giraudier@uni-potsdam.de; carlos.ventura.bort@uni-potsdam.de; mathias.weymar@uni-potsdam.de
2022-12-01T06:20:50+00:00
sword
importub
filename=package.tar
9d1aafc59beaeb53bd770c819d71cded
1484299-3
209486-1
false
true
Manon Giraudier
Carlos Ventura-Bort
Mathias Weymar
eng
uncontrolled
transcutaneous vagus nerve stimulation
Psychologie
Referiert
Department Psychologie
Import