Dokument-ID Dokumenttyp Verfasser/Autoren Herausgeber Haupttitel Abstract Auflage Verlagsort Verlag Erscheinungsjahr Seitenzahl Schriftenreihe Titel Schriftenreihe Bandzahl ISBN Quelle der Hochschulschrift Konferenzname Quelle:Titel Quelle:Jahrgang Quelle:Heftnummer Quelle:Erste Seite Quelle:Letzte Seite URN DOI Abteilungen OPUS4-61900 Wissenschaftlicher Artikel Giraudier, Manon; Ventura-Bort, Carlos; Wendt, Julia; Lischke, Alexander; Weymar, Mathias Memory advantage for untrustworthy faces The Covid-19 pandemic imposed new constraints on empirical research and forced researchers to transfer from traditional laboratory research to the online environment. This study tested the validity of a web-based episodic memory paradigm by comparing participants' memory performance for trustworthy and untrustworthy facial stimuli in a supervised laboratory setting and an unsupervised web setting. Consistent with previous results, we observed enhanced episodic memory for untrustworthy compared to trustworthy faces. Most importantly, this memory bias was comparable in the online and the laboratory experiment, suggesting that web-based procedures are a promising tool for memory research. San Fransisco PLoS 2022 11 PLoS one 17 2 10.1371/journal.pone.0264034 Department Psychologie OPUS4-47412 misc Giraudier, Manon; Ventura-Bort, Carlos; Weymar, Mathias Transcutaneous Vagus Nerve Stimulation (tVNS) Improves High-Confidence Recognition Memory but Not Emotional Word Processing Previous clinical research found that invasive vagus nerve stimulation (VNS) enhanced word recognition memory in epileptic patients, an effect assumed to be related to the activation of brainstem arousal systems. In this study, we applied non-invasive transcutaneous auricular VNS (tVNS) to replicate and extend the previous work. Using a single-blind, randomized, between-subject design, 60 healthy volunteers received active or sham stimulation during a lexical decision task, in which emotional and neutral stimuli were classified as words or non-words. In a subsequent recognition memory task (1 day after stimulation), participants' memory performance on these words and their subjective memory confidence were tested. Salivary alpha-amylase (sAA) levels, a putative indirect measure of central noradrenergic activation, were also measured before and after stimulation. During encoding, pleasant words were more accurately detected than neutral and unpleasant words. However, no tVNS effects were observed on task performance or on overall sAA level changes. tVNS also did not modulate overall recognition memory, which was particularly enhanced for pleasant emotional words. However, when hit rates were split based on confidence ratings reflecting familiarity- and recollection-based memory, higher recollection-based memory performance (irrespective of emotional category) was observed during active stimulation than during sham stimulation. To summarize, we replicated prior findings of enhanced processing and memory for emotional (pleasant) words. Whereas tVNS showed no effects on word processing, subtle effects on recollection-based memory performance emerged, which may indicate that tVNS facilitates hippocampus-mediated consolidation processes. 2020 15 Postprints der Universität Potsdam : Humanwissenschaftliche Reihe 649 urn:nbn:de:kobv:517-opus4-474125 10.25932/publishup-47412 Strukturbereich Kognitionswissenschaften OPUS4-47411 Wissenschaftlicher Artikel Giraudier, Manon; Ventura-Bort, Carlos; Weymar, Mathias Transcutaneous Vagus Nerve Stimulation (tVNS) Improves High-Confidence Recognition Memory but Not Emotional Word Processing Previous clinical research found that invasive vagus nerve stimulation (VNS) enhanced word recognition memory in epileptic patients, an effect assumed to be related to the activation of brainstem arousal systems. In this study, we applied non-invasive transcutaneous auricular VNS (tVNS) to replicate and extend the previous work. Using a single-blind, randomized, between-subject design, 60 healthy volunteers received active or sham stimulation during a lexical decision task, in which emotional and neutral stimuli were classified as words or non-words. In a subsequent recognition memory task (1 day after stimulation), participants' memory performance on these words and their subjective memory confidence were tested. Salivary alpha-amylase (sAA) levels, a putative indirect measure of central noradrenergic activation, were also measured before and after stimulation. During encoding, pleasant words were more accurately detected than neutral and unpleasant words. However, no tVNS effects were observed on task performance or on overall sAA level changes. tVNS also did not modulate overall recognition memory, which was particularly enhanced for pleasant emotional words. However, when hit rates were split based on confidence ratings reflecting familiarity- and recollection-based memory, higher recollection-based memory performance (irrespective of emotional category) was observed during active stimulation than during sham stimulation. To summarize, we replicated prior findings of enhanced processing and memory for emotional (pleasant) words. Whereas tVNS showed no effects on word processing, subtle effects on recollection-based memory performance emerged, which may indicate that tVNS facilitates hippocampus-mediated consolidation processes. Lausanne Frontiers Research Foundation 2020 13 Frontiers in Psychology 11 10.3389/fpsyg.2020.01276 Strukturbereich Kognitionswissenschaften OPUS4-56158 misc Giraudier, Manon; Ventura-Bort, Carlos; Wendt, Julia; Lischke, Alexander; Weymar, Mathias Memory advantage for untrustworthy faces: Replication across lab- and web-based studies The Covid-19 pandemic imposed new constraints on empirical research and forced researchers to transfer from traditional laboratory research to the online environment. This study tested the validity of a web-based episodic memory paradigm by comparing participants' memory performance for trustworthy and untrustworthy facial stimuli in a supervised laboratory setting and an unsupervised web setting. Consistent with previous results, we observed enhanced episodic memory for untrustworthy compared to trustworthy faces. Most importantly, this memory bias was comparable in the online and the laboratory experiment, suggesting that web-based procedures are a promising tool for memory research. Potsdam Universitätsverlag Potsdam 2022 11 Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe 1 11 urn:nbn:de:kobv:517-opus4-561586 10.25932/publishup-56158 Department Psychologie OPUS4-56157 Wissenschaftlicher Artikel Giraudier, Manon; Ventura-Bort, Carlos; Wendt, Julia; Lischke, Alexander; Weymar, Mathias Memory advantage for untrustworthy faces: Replication across lab- and web-based studies The Covid-19 pandemic imposed new constraints on empirical research and forced researchers to transfer from traditional laboratory research to the online environment. This study tested the validity of a web-based episodic memory paradigm by comparing participants' memory performance for trustworthy and untrustworthy facial stimuli in a supervised laboratory setting and an unsupervised web setting. Consistent with previous results, we observed enhanced episodic memory for untrustworthy compared to trustworthy faces. Most importantly, this memory bias was comparable in the online and the laboratory experiment, suggesting that web-based procedures are a promising tool for memory research. 2 San Francisco, California, US PLoS ONE 2022 11 PLoS ONE 17 1 11 10.1371/journal.pone.0264034 Extern OPUS4-56921 Wissenschaftlicher Artikel Giraudier, Manon; Ventura-Bort, Carlos; Weymar, Mathias Effects of transcutaneous vagus nerve stimulation (TVNS) on emotional word processing and recognition memory Malden Wiley-Blackwell 2020 1 Psychophysiology 57 S73 S73 Department Psychologie OPUS4-57548 Konferenzveröffentlichung Giraudier, Manon; Ventura-Bort, Carlos; Weymar, Mathias A pooled preliminary analysis on the effects of transcutaneous auricular vagus nerve stimulation on salivary alpha-amylase as noradrenergic biomarker Malden, Mass. [u.a.] Wiley-Blackwell 2021 1 Psychophysiology : journal of the Society for Psychophysiological Research 58 S60 S60 Department Psychologie OPUS4-57766 misc Giraudier, Manon; Ventura-Bort, Carlos; Burger, Andreas M.; Claes, Nathalie; D'Agostini, Martina; Fischer, Rico; Franssen, Mathijs; Kaess, Michael; Koenig, Julian; Liepelt, Roman; Nieuwenhuis, Sander; Sommer, Aldo; Usichenko, Taras; Van Diest, Ilse; von Leupoldt, Andreas; Warren, Christopher Michael; Weymar, Mathias Evidence for a modulating effect of transcutaneous auricular vagus nerve stimulation (taVNS) on salivary alpha-amylase as indirect noradrenergic marker: A pooled mega-analysis Background Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) has received tremendous attention as a potential neuromodulator of cognitive and affective functions, which likely exerts its effects via activation of the locus coeruleus-noradrenaline (LC-NA) system. Reliable effects of taVNS on markers of LC-NA system activity, however, have not been demonstrated yet. Methods The aim of the present study was to overcome previous limitations by pooling raw data from a large sample of ten taVNS studies (371 healthy participants) that collected salivary alpha-amylase (sAA) as a potential marker of central NA release. Results While a meta-analytic approach using summary statistics did not yield any significant effects, linear mixed model analyses showed that afferent stimulation of the vagus nerve via taVNS increased sAA levels compared to sham stimulation (b = 0.16, SE = 0.05, p = 0.001). When considering potential confounders of sAA, we further replicated previous findings on the diurnal trajectory of sAA activity. Conclusion(s) Vagal activation via taVNS increases sAA release compared to sham stimulation, which likely substantiates the assumption that taVNS triggers NA release. Moreover, our results highlight the benefits of data pooling and data sharing in order to allow stronger conclusions in research. 2022 11 Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe 808 1378 1388 urn:nbn:de:kobv:517-opus4-577668 10.25932/publishup-57766 Strukturbereich Kognitionswissenschaften OPUS4-57767 Wissenschaftlicher Artikel Giraudier, Manon; Ventura-Bort, Carlos; Burger, Andreas M.; Claes, Nathalie; D'Agostini, Martina; Fischer, Rico; Franssen, Mathijs; Kaess, Michael; Koenig, Julian; Liepelt, Roman; Nieuwenhuis, Sander; Sommer, Aldo; Usichenko, Taras; Van Diest, Ilse; von Leupoldt, Andreas; Warren, Christopher Michael; Weymar, Mathias Evidence for a modulating effect of transcutaneous auricular vagus nerve stimulation (taVNS) on salivary alpha-amylase as indirect noradrenergic marker: A pooled mega-analysis Background Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) has received tremendous attention as a potential neuromodulator of cognitive and affective functions, which likely exerts its effects via activation of the locus coeruleus-noradrenaline (LC-NA) system. Reliable effects of taVNS on markers of LC-NA system activity, however, have not been demonstrated yet. Methods The aim of the present study was to overcome previous limitations by pooling raw data from a large sample of ten taVNS studies (371 healthy participants) that collected salivary alpha-amylase (sAA) as a potential marker of central NA release. Results While a meta-analytic approach using summary statistics did not yield any significant effects, linear mixed model analyses showed that afferent stimulation of the vagus nerve via taVNS increased sAA levels compared to sham stimulation (b = 0.16, SE = 0.05, p = 0.001). When considering potential confounders of sAA, we further replicated previous findings on the diurnal trajectory of sAA activity. Conclusion(s) Vagal activation via taVNS increases sAA release compared to sham stimulation, which likely substantiates the assumption that taVNS triggers NA release. Moreover, our results highlight the benefits of data pooling and data sharing in order to allow stronger conclusions in research. 6 New York, NY, USA Elsevier 2022 11 Brain Stimulation 15 1378 1388 10.1016/j.brs.2022.09.009 Extern