@article{OzcelikayKurbanogluYarmanetal.2020,
  author    = {Ozcelikay, Goksu and Kurbanoglu, Sevinc and Yarman, Aysu and Scheller, Frieder W. and Ozkan, Sibel A.},
  title     = {Au-Pt nanoparticles based molecularly imprinted nanosensor for electrochemical detection of the lipopeptide antibiotic drug Daptomycin},
  series = {Sensors and actuators : B, Chemical},
  volume    = {320},
  journal   = {Sensors and actuators : B, Chemical},
  publisher = {Elsevier Science},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2020.128285},
  pages     = {7},
  year      = {2020},
  abstract  = {In this work, a novel electrochemical molecularly imprinted polymer (MIP) sensor for the detection of the lipopeptide antibiotic Daptomycin (DAP) is presented which integrates gold decorated platinum nanoparticles (Au-Pt NPs) into the nanocomposite film. The sensor was prepared by electropolymerization of o-phenylenediamine (o-PD) in the presence of DAP using cyclic voltammetry. Cyclic voltammetry and differential pulse voltammetry were applied to follow the changes in the MIP-layer related to rebinding and removal of the target DAP by using the redox marker [Fe(CN)(6)](3-/4-). Under optimized operational conditions, the MIP/Au-Pt NPs/ GCE nanosensor exhibits a linear response in the range of 1-20 pM towards DAP. The limit of detection and limit of quantification were determined to be 0.161pM +/- 0.012 and 0.489pM +/- 0.012, respectively. The sensitivity towards the antibiotics Vancomycin and Erythromycin and the amino acids glycine and tryptophan was below 7 percent as compared with DAP. Moreover, the nanosensor was also successfully used for the detection of DAP in deproteinated human serum samples.},
  language  = {en}
}
@article{SchroedterSchneiderRemusetal.2020,
  author    = {Schroedter, Linda and Schneider, Roland and Remus, Lisa and Venus, Joachim},
  title     = {L-(+)-lactic acid from reed},
  series = {Resources},
  volume    = {9},
  journal   = {Resources},
  number    = {7},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2079-9276},
  doi       = {10.3390/resources9070089},
  pages     = {12},
  year      = {2020},
  abstract  = {Biotechnological production of lactic acid (LA) is based on the so-called first generation feedstocks, meaning sugars derived from food and feed crops such as corn, sugarcane and cassava. The aim of this study was to exploit the potential of a second generation resource: Common reed (Phragmites australis) is a powerfully reproducing sweet grass which grows in wetlands and creates vast monocultural populations. This lignocellulose biomass bears the possibility to be refined to value-added products, without competing with agro industrial land. Besides utilizing reed as a renewable and inexpensive substrate, low-cost nutritional supplementation was analyzed for the fermentation of thermophilicBacilluscoagulans.Various nutritional sources such as baker's and brewer's yeast, lucerne green juice and tryptone were investigated for the replacement of yeast extract. The structure of the lignocellulosic material was tackled by chemical treatment (1\% NaOH) and enzymatic hydrolysis (Cellic(R)CTec2).B.coagulansDSM ID 14-300 was employed for the homofermentative conversion of the released hexose and pentose sugars to polymerizable L-(+)-LA of over 99.5\% optical purity. The addition of autolyzed baker's yeast led to the best results of fermentation, enabling an LA titer of 28.3 g L(-1)and a yield of 91.6\%.},
  language  = {en}
}
@article{StichMartinMoralesetal.2020,
  author    = {Stich, Daniel and Martin, Rosa and Morales, Jose and Lopez-Comino, Jose Angel and Mancilla, Flor de Lis},
  title     = {Slip partitioning in the 2016 Alboran Sea earthquake sequence (western Mediterranean)},
  series = {Frontiers in Earth Science},
  volume    = {8},
  journal   = {Frontiers in Earth Science},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-6463},
  doi       = {10.3389/feart.2020.587356},
  pages     = {19},
  year      = {2020},
  abstract  = {AM(W)= 5.1 earthquake on January 21st, 2016 marked the beginning of a significant seismic sequence in the southern Alboran Sea, culminating in aM(W)= 6.3 earthquake on January 25th, and continuing with further moderate magnitude earthquakes until March. We use data from 35 seismic broadband stations in Spain, Morocco and Portugal to relocate the seismicity, estimate seismic moment tensors, and isolate regional apparent source time functions for the main earthquake. Relocation and regional moment tensor inversion consistently yield very shallow depths for the majority of events. We obtain 50 moment tensors for the sequence, showing a mixture of strike-slip faulting for the foreshock and the main event and reverse faulting for the major aftershocks. The leading role of reverse focal mechanisms among the aftershocks may be explained by the geometry of the fault network. The mainshock nucleates at a bend along the left-lateral Al-Idrisi fault, introducing local transpression within the transtensional Alboran Basin. The shallow depths of the 2016 Alboran Sea earthquakes may favor slip-partitioning on the involved faults. Apparent source durations for the main event suggest a similar to 21 km long, asymmetric rupture that propagates primarily toward NE into the restraining fault segment, with fast rupture speed of similar to 3.0 km/s. Consistently, the inversion for laterally variable fault displacement situates the main slip in the restraining segment. The partitioning into strike-slip rupture and dip-slip aftershocks confirms a non-optimal orientation of this segment, and suggests that the 2016 event settled a slip deficit from previous ruptures that could not propagate into the stronger restraining segment.},
  language  = {en}
}
@article{CrisologoHeistermann2020,
  author    = {Crisologo, Irene and Heistermann, Maik},
  title     = {Using ground radar overlaps to verify the retrieval of calibration bias estimates from spaceborne platforms},
  series = {Atmospheric measurement techniques : an interactive open access journal of the European Geosciences Union},
  volume    = {13},
  journal   = {Atmospheric measurement techniques : an interactive open access journal of the European Geosciences Union},
  number    = {2},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1867-1381},
  doi       = {10.5194/amt-13-645-2020},
  pages     = {645 -- 659},
  year      = {2020},
  abstract  = {Many institutions struggle to tap into the potential of their large archives of radar reflectivity: these data are often affected by miscalibration, yet the bias is typically unknown and temporally volatile. Still, relative calibration techniques can be used to correct the measurements a posteriori. For that purpose, the usage of spaceborne reflectivity observations from the Tropical Rainfall Measuring Mission (TRMM) and Global Precipitation Measurement (GPM) platforms has become increasingly popular: the calibration bias of a ground radar (GR) is estimated from its average reflectivity difference to the spaceborne radar (SR). Recently, Crisologo et al. (2018) introduced a formal procedure to enhance the reliability of such estimates: each match between SR and GR observations is assigned a quality index, and the calibration bias is inferred as a quality-weighted average of the differences between SR and GR. The relevance of quality was exemplified for the Subic S-band radar in the Philippines, which is greatly affected by partial beam blockage. The present study extends the concept of quality-weighted averaging by accounting for path-integrated attenuation (PIA) in addition to beam blockage. This extension becomes vital for radars that operate at the C or X band. Correspondingly, the study setup includes a C-band radar that substantially overlaps with the S-band radar. Based on the extended quality-weighting approach, we retrieve, for each of the two ground radars, a time series of calibration bias estimates from suitable SR overpasses. As a result of applying these estimates to correct the ground radar observations, the consistency between the ground radars in the region of overlap increased substantially. Furthermore, we investigated if the bias estimates can be interpolated in time, so that ground radar observations can be corrected even in the absence of prompt SR overpasses. We found that a moving average approach was most suitable for that purpose, although limited by the absence of explicit records of radar maintenance operations.},
  language  = {en}
}
@article{PaulyNottbusch2020,
  author    = {Pauly, Dennis Nikolas and Nottbusch, Guido},
  title     = {The Influence of the German Capitalization Rules on Reading},
  series = {Frontiers in Communication},
  volume    = {5},
  journal   = {Frontiers in Communication},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2297-900X},
  doi       = {10.3389/fcomm.2020.00015},
  pages     = {15},
  year      = {2020},
  abstract  = {German orthography systematically marks all nouns (even other nominalized word classes) by capitalizing their first letter. It is often claimed that readers benefit from the uppercase-letter syntactic and semantic information, which makes the processing of sentences easier (e.g., Bock et al., 1985, 1989). In order to test this hypothesis, we asked 54 German readers to read single sentences systematically manipulated by a target word (N). In the experimental condition (EXP), we used semantic priming (in the following example: sick -> cold) in order to build up a strong expectation of a noun, which was actually an attribute for the following noun (N+1) (translated to English e.g., "The sick writer had a cold (N) nose (N+1) ..."). The sentences in the control condition were built analogously, but word N was purposefully altered (keeping word length and frequency constant) to make its interpretation as a noun extremely unlikely (e.g., "The sick writer had a blue (N) nose (N+1) ..."). In both conditions, the sentences were presented either following German standard orthography (Cap) or in lowercase spelling (NoCap). The capitalized nouns in the EXP/Cap condition should then prevent garden-path parsing, as capital letters can be recognized parafoveally. However, in the EXP/NoCap condition, we expected a garden-path effect on word N+1 affecting first-pass fixations and the number of regressions, as the reader realizes that word N is instead an adjective. As the control condition does not include a garden-path, we expected to find (small) effects of the violation of the orthographic rule in the CON/NoCap condition, but no garden-path effect. As a global result, it can be stated that reading sentences in which nouns are not marked by a majuscule slows a native German reader down significantly, but from an absolute point of view, the effect is small. Compared with other manipulations (e.g., transpositions or substitutions), a lowercase letter still represents the correct allograph in the correct position without affecting phonology. Furthermore, most German readers do have experience with other alphabetic writing systems that lack consistent noun capitalization, and in (private) digital communication lowercase nouns are quite common. Although our garden-path sentences did not show the desired effect, we found an indication of grammatical pre-processing enabled by the majuscule in the regularly spelled sentences: In the case of high noun frequency, we post hoc located parafovea-on-fovea effects, i.e., longer fixation durations, on the attributive adjective (word N). These benefits of capitalization could only be detected under specific circumstances. In other cases, we conclude that longer reading durations are mainly the result of disturbance in readers' habituation when the expected capitalization is missing.},
  language  = {en}
}
@article{SanchezGarcia2020,
  author    = {Sanchez Garcia, Maria Clemencia},
  title     = {Las unidades fraseol{\´o}gicas del parlache como elementos evocadores de la oralidad ficcional en la novela Rosario Tijeras, de Jorge Franco y su traducci{\´o}n al alem{\´a}n},
  series = {Ling{\"u}{\´i}stica y literatura},
  volume    = {41},
  journal   = {Ling{\"u}{\´i}stica y literatura},
  number    = {77},
  publisher = {Universidad de Antioquia},
  address   = {Medell{\´i}n},
  issn      = {0120-5587},
  doi       = {10.17533/udea.lyl.n77a17},
  pages     = {385 -- 409},
  year      = {2020},
  abstract  = {Este estudioanaliz{\´o}c{\´o}mose evoca la oralidad ficcional en la novela Rosario Tijerasa trav{\´e}s de la variaci{\´o}n ling{\"u}{\´i}stica. Para ello, se analiz{\´o}un corpus de veinteunidades fraseol{\´o}gicas presentes en la novela y su traducci{\´o}n al alem{\´a}n. En esta novela negra, el autor recurri{\´o}a un lenguaje coloquial llamado parlache. Este art{\´i}culo, por tanto,se pretender{\´a} establecer c{\´o}mo estas unidades fraseol{\´o}gicas t{\´i}picas del parlachecontribuyerona la construcci{\´o}n de un di{\´a}logo hablado veros{\´i}mil, adem{\´a}s de determinar las divergencias de traducci{\´o}n y profundizar en la descripci{\´o}n de la variaci{\´o}n ling{\"u}{\´i}stica a trav{\´e}s de las unidades fraseol{\´o}gicas.},
  language  = {es}
}
@article{MaoutsaReichOpper2020,
  author    = {Maoutsa, Dimitra and Reich, Sebastian and Opper, Manfred},
  title     = {Interacting particle solutions of Fokker-Planck equations through gradient-log-density estimation},
  series = {Entropy},
  volume    = {22},
  journal   = {Entropy},
  number    = {8},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1099-4300},
  doi       = {10.3390/e22080802},
  pages     = {35},
  year      = {2020},
  abstract  = {Fokker-Planck equations are extensively employed in various scientific fields as they characterise the behaviour of stochastic systems at the level of probability density functions. Although broadly used, they allow for analytical treatment only in limited settings, and often it is inevitable to resort to numerical solutions. Here, we develop a computational approach for simulating the time evolution of Fokker-Planck solutions in terms of a mean field limit of an interacting particle system. The interactions between particles are determined by the gradient of the logarithm of the particle density, approximated here by a novel statistical estimator. The performance of our method shows promising results, with more accurate and less fluctuating statistics compared to direct stochastic simulations of comparable particle number. Taken together, our framework allows for effortless and reliable particle-based simulations of Fokker-Planck equations in low and moderate dimensions. The proposed gradient-log-density estimator is also of independent interest, for example, in the context of optimal control.},
  language  = {en}
}
@article{KrasotkinaGoetzHoehleetal.2020,
  author    = {Krasotkina, Anna and G{\"o}tz, Antonia and H{\"o}hle, Barbara and Schwarzer, Gudrun},
  title     = {Infants' gaze patterns for same-race and other-race faces, and the other-race effect},
  series = {Brain Sciences},
  volume    = {10},
  journal   = {Brain Sciences},
  number    = {6},
  publisher = {Brain Sciences},
  address   = {Basel},
  issn      = {2076-3425},
  doi       = {10.3390/brainsci10060331},
  pages     = {12},
  year      = {2020},
  abstract  = {The other-race effect (ORE) can be described as difficulties in discriminating between faces of ethnicities other than one's own, and can already be observed at approximately 9 months of age. Recent studies also showed that infants visually explore same-and other-race faces differently. However, it is still unclear whether infants' looking behavior for same- and other-race faces is related to their face discrimination abilities. To investigate this question we conducted a habituation-dishabituation experiment to examine Caucasian 9-month-old infants' gaze behavior, and their discrimination of same- and other-race faces, using eye-tracking measurements. We found that infants looked longer at the eyes of same-race faces over the course of habituation, as compared to other-race faces. After habituation, infants demonstrated a clear other-race effect by successfully discriminating between same-race faces, but not other-race faces. Importantly, the infants' ability to discriminate between same-race faces significantly correlated with their fixation time towards the eyes of same-race faces during habituation. Thus, our findings suggest that for infants old enough to begin exhibiting the ORE, gaze behavior during habituation is related to their ability to differentiate among same-race faces, compared to other-race faces.},
  language  = {en}
}
@article{PereraBoeckmann2020,
  author    = {Perera, Upeksha and B{\"o}ckmann, Christine},
  title     = {Solutions of Sturm-Liouville problems},
  series = {Mathematics},
  volume    = {8},
  journal   = {Mathematics},
  number    = {11},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2227-7390},
  doi       = {10.3390/math8112074},
  pages     = {14},
  year      = {2020},
  abstract  = {This paper further improves the Lie group method with Magnus expansion proposed in a previous paper by the authors, to solve some types of direct singular Sturm-Liouville problems. Next, a concrete implementation to the inverse Sturm-Liouville problem algorithm proposed by Barcilon (1974) is provided. Furthermore, computational feasibility and applicability of this algorithm to solve inverse Sturm-Liouville problems of higher order (for n=2,4) are verified successfully. It is observed that the method is successful even in the presence of significant noise, provided that the assumptions of the algorithm are satisfied. In conclusion, this work provides a method that can be adapted successfully for solving a direct (regular/singular) or inverse Sturm-Liouville problem (SLP) of an arbitrary order with arbitrary boundary conditions.},
  language  = {en}
}
@article{SchenkeSchjeidePuescheletal.2020,
  author    = {Schenke, Maren and Schjeide, Brit-Maren and P{\"u}schel, Gerhard Paul and Seeger, Bettina},
  title     = {Analysis of motor neurons differentiated from human induced pluripotent stem cells for the use in cell-based Botulinum neurotoxin activity assays},
  series = {Toxins},
  volume    = {12},
  journal   = {Toxins},
  number    = {5},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2072-6651},
  doi       = {10.3390/toxins12050276},
  pages     = {20},
  year      = {2020},
  abstract  = {Botulinum neurotoxins (BoNTs) are potent neurotoxins produced by bacteria, which inhibit neurotransmitter release, specifically in their physiological target known as motor neurons (MNs). For the potency assessment of BoNTs produced for treatment in traditional and aesthetic medicine, the mouse lethality assay is still used by the majority of manufacturers, which is ethically questionable in terms of the 3Rs principle. In this study, MNs were differentiated from human induced pluripotent stem cells based on three published protocols. The resulting cell populations were analyzed for their MN yield and their suitability for the potency assessment of BoNTs. MNs produce specific gangliosides and synaptic proteins, which are bound by BoNTs in order to be taken up by receptor-mediated endocytosis, which is followed by cleavage of specific soluble N-ethylmaleimide-sensitive-factor attachment receptor (SNARE) proteins required for neurotransmitter release. The presence of receptors and substrates for all BoNT serotypes was demonstrated in MNs generated in vitro. In particular, the MN differentiation protocol based on Du et al. yielded high numbers of MNs in a short amount of time with high expression of BoNT receptors and targets. The resulting cells are more sensitive to BoNT/A1 than the commonly used neuroblastoma cell line SiMa. MNs are, therefore, an ideal tool for being combined with already established detection methods.},
  language  = {en}
}