@article{Schwarz2019,
  author    = {Schwarz, Anja},
  title     = {Melancholia},
  series = {Cultural studies review},
  volume    = {25},
  journal   = {Cultural studies review},
  number    = {2},
  publisher = {Melbourne Univ. Press},
  address   = {Sydney},
  issn      = {1837-8692},
  doi       = {10.5130/csr.v25i2.6918},
  pages     = {259 -- 261},
  year      = {2019},
  language  = {en}
}
@article{ZiesemerHuettelBalderjahn2019,
  author    = {Ziesemer, Florence and H{\"u}ttel, Alexandra and Balderjahn, Ingo},
  title     = {Anti-Consumption},
  series = {Sustainability},
  volume    = {11},
  journal   = {Sustainability},
  number    = {23},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2071-1050},
  doi       = {10.3390/su11236663},
  pages     = {16},
  year      = {2019},
  abstract  = {Transcending the conventional debate around efficiency in sustainable consumption, anti-consumption patterns leading to decreased levels of material consumption have been gaining importance. Change agents are crucial for the promotion of such patterns, so there may be lessons for governance interventions that can be learnt from the every-day experiences of those who actively implement and promote sustainability in the field of anti-consumption. Eighteen social innovation pioneers, who engage in and diffuse practices of voluntary simplicity and collaborative consumption as sustainable options of anti-consumption share their knowledge and personal insights in expert interviews for this research. Our qualitative content analysis reveals drivers, barriers, and governance strategies to strengthen anti-consumption patterns, which are negotiated between the market, the state, and civil society. Recommendations derived from the interviews concern entrepreneurship, municipal infrastructures in support of local grassroots projects, regulative policy measures, more positive communication to strengthen the visibility of initiatives and emphasize individual benefits, establishing a sense of community, anti-consumer activism, and education. We argue for complementary action between top-down strategies, bottom-up initiatives, corporate activities, and consumer behavior. The results are valuable to researchers, activists, marketers, and policymakers who seek to enhance their understanding of materially reduced consumption patterns based on the real-life experiences of active pioneers in the field.},
  language  = {en}
}
@article{OzcelikayKurbanogluZhangetal.2019,
  author    = {Ozcelikay, Goksu and Kurbanoglu, Sevinc and Zhang, Xiaorong and S{\"o}z, {\c{C}}ağla Kosak and Wollenberger, Ulla and Ozkan, Sibel A. and Yarman, Aysu and Scheller, Frieder W.},
  title     = {Electrochemical MIP Sensor for Butyrylcholinesterase},
  series = {Polymers},
  volume    = {11},
  journal   = {Polymers},
  number    = {12},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4360},
  doi       = {10.3390/polym11121970},
  pages     = {11},
  year      = {2019},
  abstract  = {Molecularly imprinted polymers (MIPs) mimic the binding sites of antibodies by substituting the amino acid-scaffold of proteins by synthetic polymers. In this work, the first MIP for the recognition of the diagnostically relevant enzyme butyrylcholinesterase (BuChE) is presented. The MIP was prepared using electropolymerization of the functional monomer o-phenylenediamine and was deposited as a thin film on a glassy carbon electrode by oxidative potentiodynamic polymerization. Rebinding and removal of the template were detected by cyclic voltammetry using ferricyanide as a redox marker. Furthermore, the enzymatic activity of BuChE rebound to the MIP was measured via the anodic oxidation of thiocholine, the reaction product of butyrylthiocholine. The response was linear between 50 pM and 2 nM concentrations of BuChE with a detection limit of 14.7 pM. In addition to the high sensitivity for BuChE, the sensor responded towards pseudo-irreversible inhibitors in the lower mM range.},
  language  = {en}
}
@article{NivenAbelSchlegeletal.2019,
  author    = {Niven, Robert K. and Abel, Markus and Schlegel, Michael and Waldrip, Steven H.},
  title     = {Maximum Entropy Analysis of Flow Networks: Theoretical Foundation and Applications},
  series = {Entropy},
  volume    = {21},
  journal   = {Entropy},
  number    = {8},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1099-4300},
  doi       = {10.3390/e21080776},
  pages     = {776},
  year      = {2019},
  abstract  = {The concept of a "flow network"-a set of nodes and links which carries one or more flows-unites many different disciplines, including pipe flow, fluid flow, electrical, chemical reaction, ecological, epidemiological, neurological, communications, transportation, financial, economic and human social networks. This Feature Paper presents a generalized maximum entropy framework to infer the state of a flow network, including its flow rates and other properties, in probabilistic form. In this method, the network uncertainty is represented by a joint probability function over its unknowns, subject to all that is known. This gives a relative entropy function which is maximized, subject to the constraints, to determine the most probable or most representative state of the network. The constraints can include "observable" constraints on various parameters, "physical" constraints such as conservation laws and frictional properties, and "graphical" constraints arising from uncertainty in the network structure itself. Since the method is probabilistic, it enables the prediction of network properties when there is insufficient information to obtain a deterministic solution. The derived framework can incorporate nonlinear constraints or nonlinear interdependencies between variables, at the cost of requiring numerical solution. The theoretical foundations of the method are first presented, followed by its application to a variety of flow networks.},
  language  = {en}
}
@article{SchuetzeFuerstMielkeetal.2017,
  author    = {Sch{\"u}tze, Franziska and F{\"u}rst, Steffen and Mielke, Jahel and Steudle, Gesine A. and Wolf, Sarah and J{\"a}ger, Carlo C.},
  title     = {The Role of Sustainable Investment in Climate Policy},
  series = {Sustainability},
  volume    = {9},
  journal   = {Sustainability},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2071-1050},
  doi       = {10.3390/su9122221},
  pages     = {19},
  year      = {2017},
  abstract  = {Reaching the Sustainable Development Goals requires a fundamental socio-economic transformation accompanied by substantial investment in low-carbon infrastructure. Such a sustainability transition represents a non-marginal change, driven by behavioral factors and systemic interactions. However, typical economic models used to assess a sustainability transition focus on marginal changes around a local optimum, whichby constructionlead to negative effects. Thus, these models do not allow evaluating a sustainability transition that might have substantial positive effects. This paper examines which mechanisms need to be included in a standard computable general equilibrium model to overcome these limitations and to give a more comprehensive view of the effects of climate change mitigation. Simulation results show that, given an ambitious greenhouse gas emission constraint and a price of carbon, positive economic effects are possible if (1) technical progress results (partly) endogenously from the model and (2) a policy intervention triggering an increase of investment is introduced. Additionally, if (3) the investment behavior of firms is influenced by their sales expectations, the effects are amplified. The results provide suggestions for policy-makers, because the outcome indicates that investment-oriented climate policies can lead to more desirable outcomes in economic, social and environmental terms.},
  language  = {en}
}
@article{WeisshuhnRecklingStachowetal.2017,
  author    = {Weisshuhn, Peter and Reckling, Moritz and Stachow, Ulrich and Wiggering, Hubert},
  title     = {Supporting Agricultural Ecosystem Services through the Integration of Perennial Polycultures into Crop Rotations},
  series = {Sustainability},
  volume    = {9},
  journal   = {Sustainability},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2071-1050},
  doi       = {10.3390/su9122267},
  pages     = {20},
  year      = {2017},
  abstract  = {This review analyzes the potential role and long-term effects of field perennial polycultures (mixtures) in agricultural systems, with the aim of reducing the trade-offs between provisioning and regulating ecosystem services. First, crop rotations are identified as a suitable tool for the assessment of the long-term effects of perennial polycultures on ecosystem services, which are not visible at the single-crop level. Second, the ability of perennial polycultures to support ecosystem services when used in crop rotations is quantified through eight agricultural ecosystem services. Legume-grass mixtures and wildflower mixtures are used as examples of perennial polycultures, and compared with silage maize as a typical crop for biomass production. Perennial polycultures enhance soil fertility, soil protection, climate regulation, pollination, pest and weed control, and landscape aesthetics compared with maize. They also score lower for biomass production compared with maize, which confirms the trade-off between provisioning and regulating ecosystem services. However, the additional positive factors provided by perennial polycultures, such as reduced costs for mineral fertilizer, pesticides, and soil tillage, and a significant preceding crop effect that increases the yields of subsequent crops, should be taken into account. However, a full assessment of agricultural ecosystem services requires a more holistic analysis that is beyond the capabilities of current frameworks.},
  language  = {en}
}
@article{PosovszkyRoeslerBeckeretal.2019,
  author    = {Posovszky, Carsten and Roesler, Vreni Helen and Becker, Sebastian and Iven, Enno and Hudert, Christian and Ebinger, Friedrich and Calvano, Claudia and Warschburger, Petra},
  title     = {Roles of Lactose and Fructose Malabsorption and Dietary Outcomes in Children Presenting with Chronic Abdominal Pain},
  series = {Nutrients},
  volume    = {11},
  journal   = {Nutrients},
  number    = {12},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2072-6643},
  doi       = {10.3390/nu11123063},
  pages     = {13},
  year      = {2019},
  abstract  = {Intolerance to lactose or fructose is frequently diagnosed in children with chronic abdominal pain (CAP). However, the causal relationship remains a matter of discussion. A cohort of 253 patients, aged 7-12 years, presenting with unexplained CAP received standardized diagnostics. Additional diagnostic tests were performed based on their medical history and physical and laboratory investigations. Fructose and lactose hydrogen breath tests (H2BT) as well as empiric diagnostic elimination diets were performed in 135 patients reporting abdominal pain related to the consumption of lactose or fructose to evaluate carbohydrate intolerance as a potential cause of CAP. Carbohydrate malabsorption by H2BT was found in 55 (41\%) out of 135 patients. An abnormal increase in H2BT was revealed in 30\% (35/118) of patients after fructose consumption and in 18\% (20/114) of patients after lactose administration. Forty-six percent (25/54) reported pain relief during a diagnostic elimination diet. In total, 17 patients had lactose malabsorption, 29 fructose malabsorption, and nine combined carbohydrate malabsorption. Carbohydrate intolerance as a cause of CAP was diagnosed at follow-up in only 18\% (10/55) of patients with malabsorption after the elimination of the respective carbohydrate. Thus, carbohydrate malabsorption appears to be an incidental finding in children with functional abdominal pain disorders, rather than its cause. Therefore, testing of carbohydrate intolerance should only be considered in children with a strong clinical suspicion and with the goal to prevent long-term unnecessary dietary restrictions in children suffering from CAP.},
  language  = {en}
}
@article{CoduttiBenteFaivreetal.2019,
  author    = {Codutti, Agnese and Bente, Klaas and Faivre, Damien and Klumpp, Stefan},
  title     = {Chemotaxis in external fields: Simulations for active magnetic biological matter},
  series = {PLoS Computational Biology : a new community journal},
  volume    = {15},
  journal   = {PLoS Computational Biology : a new community journal},
  number    = {12},
  publisher = {PLoS},
  address   = {San Fransisco},
  issn      = {1553-734X},
  doi       = {10.1371/journal.pcbi.1007548},
  pages     = {26},
  year      = {2019},
  abstract  = {The movement of microswimmers is often described by active Brownian particle models. Here we introduce a variant of these models with several internal states of the swimmer to describe stochastic strategies for directional swimming such as run and tumble or run and reverse that are used by microorganisms for chemotaxis. The model includes a mechanism to generate a directional bias for chemotaxis and interactions with external fields (e.g., gravity, magnetic field, fluid flow) that impose forces or torques on the swimmer. We show how this modified model can be applied to various scenarios: First, the run and tumble motion of E. coli is used to establish a paradigm for chemotaxis and investigate how it is affected by external forces. Then, we study magneto-aerotaxis in magnetotactic bacteria, which is biased not only by an oxygen gradient towards a preferred concentration, but also by magnetic fields, which exert a torque on an intracellular chain of magnets. We study the competition of magnetic alignment with active reorientation and show that the magnetic orientation can improve chemotaxis and thereby provide an advantage to the bacteria, even at rather large inclination angles of the magnetic field relative to the oxygen gradient, a case reminiscent of what is expected for the bacteria at or close to the equator. The highest gain in chemotactic velocity is obtained for run and tumble with a magnetic field parallel to the gradient, but in general a mechanism for reverse motion is necessary to swim against the magnetic field and a run and reverse strategy is more advantageous in the presence of a magnetic torque. This finding is consistent with observations that the dominant mode of directional changes in magnetotactic bacteria is reversal rather than tumbles. Moreover, it provides guidance for the design of future magnetic biohybrid swimmers. Author summary In this paper, we propose a modified Active Brownian particle model to describe bacterial swimming behavior under the influence of external forces and torques, in particular of a magnetic torque. This type of interaction is particularly important for magnetic biohybrids (i.e. motile bacteria coupled to a synthetic magnetic component) and for magnetotactic bacteria (i.e. bacteria with a natural intracellular magnetic chain), which perform chemotaxis to swim along chemical gradients, but are also directed by an external magnetic field. The model allows us to investigate the benefits and disadvantages of such coupling between two different directionality mechanisms. In particular we show that the magnetic torque can speed chemotaxis up in some conditions, while it can hinder it in other cases. In addition to an understanding of the swimming strategies of naturally magnetotactic organisms, the results may guide the design of future biomedical devices.},
  language  = {en}
}
@misc{WongMasonBruneetal.2019,
  author    = {Wong, Kevin and Mason, Emily and Brune, Sascha and East, Madison and Edmonds, Marie and Zahirovic, Sabin},
  title     = {Deep Carbon Cycling Over the Past 200 Million Years: A Review of Fluxes in Different Tectonic Settings},
  series = {Frontiers in Earth Science},
  volume    = {7},
  journal   = {Frontiers in Earth Science},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {2296-6463},
  doi       = {10.3389/feart.2019.00263},
  pages     = {22},
  year      = {2019},
  language  = {en}
}
@article{MeiKochovskiRoaetal.2019,
  author    = {Mei, Shilin and Kochovski, Zdravko and Roa, Rafael and Gu, Sasa and Xu, Xiaohui and Yu, Hongtao and Dzubiella, Joachim and Ballauff, Matthias and Lu, Yan},
  title     = {Enhanced Catalytic Activity of Gold@Polydopamine Nanoreactors with Multi-compartment Structure Under NIR Irradiation},
  series = {Nano-Micro Letters},
  volume    = {11},
  journal   = {Nano-Micro Letters},
  number    = {1},
  publisher = {Shanghai JIAO TONG univ press},
  address   = {Shanghai},
  issn      = {2311-6706},
  doi       = {10.1007/s40820-019-0314-9},
  pages     = {16},
  year      = {2019},
  abstract  = {Photothermal conversion (PTC) nanostructures have great potential for applications in many fields, and therefore, they have attracted tremendous attention. However, the construction of a PTC nanoreactor with multi-compartment structure to achieve the combination of unique chemical properties and structural feature is still challenging due to the synthetic difficulties. Herein, we designed and synthesized a catalytically active, PTC gold (Au)@polydopamine (PDA) nanoreactor driven by infrared irradiation using assembled PS-b-P2VP nanosphere as soft template. The particles exhibit multi-compartment structure which is revealed by 3D electron tomography characterization technique. They feature permeable shells with tunable shell thickness. Full kinetics for the reduction reaction of 4-nitrophenol has been investigated using these particles as nanoreactors and compared with other reported systems. Notably, a remarkable acceleration of the catalytic reaction upon near-infrared irradiation is demonstrated, which reveals for the first time the importance of the synergistic effect of photothermal conversion and complex inner structure to the kinetics of the catalytic reduction. The ease of synthesis and fresh insights into catalysis will promote a new platform for novel nanoreactor studies.},
  language  = {en}
}
@article{SahaOwenOrretal.2019,
  author    = {Saha, Sourav and Owen, Lewis A. and Orr, Elizabeth N. and Caffee, Marc W.},
  title     = {Cosmogenic Be-10 and equilibrium-line altitude dataset of Holocene glacier advances in the Himalayan-Tibetan orogen},
  series = {Data in brief},
  volume    = {26},
  journal   = {Data in brief},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2352-3409},
  doi       = {10.1016/j.dib.2019.104412},
  pages     = {13},
  year      = {2019},
  abstract  = {A comprehensive analysis of the variable temporal and spatial responses of tropical-subtropical high-altitude glaciers to climate change is critical for successful model predictions and environmental risk assessment in the Himalayan-Tibetan orogen. High-frequency Holocene glacier chronostratigraphies are therefore reconstructed in 79 glaciated valleys across the orogen using 519 published and 16 new terrestrial cosmogenic 10Be exposure age dataset. Published 10Be ages are compiled only for moraine boulders (excluding bedrock ages). These ages are recalculated using the latest ICE-D production rate calibration database and the scaling scheme models. Outliers for the individual moraine are detected using the Chauvenet's criterion. In addition, past equilibrium-line altitudes (ELAs) are determined using the area-altitude (AA), area accumulation ratio (AAR), and toe-headwall accumulation ratio (THAR) methods for each glacier advance. The modern maximum elevations of lateral moraines (MELM) are also used to estimate modern ELAs and as an independent check on mean ELAs derived using the above three methods. These data may serve as an essential archive for future studies focusing on the cryospheric and environmental changes in the Himalayan-Tibetan orogen. A more comprehensive analysis of the published and new 10Be ages and ELA results and a list of references are presented in Saha et al. (2019, High-frequency Holocene glacier fluctuations in the Himalayan-Tibetan orogen. Quaternary Science Reviews, 220, 372-400).},
  language  = {en}
}
@article{RossbergGaedkeKratina2019,
  author    = {Rossberg, Axel G. and Gaedke, Ursula and Kratina, Pavel},
  title     = {Dome patterns in pelagic size spectra reveal strong trophic cascades},
  series = {Nature Communications},
  volume    = {10},
  journal   = {Nature Communications},
  publisher = {Nature Publ. Group},
  address   = {London},
  issn      = {2041-1723},
  doi       = {10.1038/s41467-019-12289-0},
  pages     = {11},
  year      = {2019},
  abstract  = {In ecological communities, especially the pelagic zones of aquatic ecosystems, certain bodysize ranges are often over-represented compared to others. Community size spectra, the distributions of community biomass over the logarithmic body-mass axis, tend to exhibit regularly spaced local maxima, called "domes", separated by steep troughs. Contrasting established theory, we explain these dome patterns as manifestations of top-down trophic cascades along aquatic food chains. Compiling high quality size-spectrum data and comparing these with a size-spectrum model introduced in this study, we test this theory and develop a detailed picture of the mechanisms by which bottom-up and top-down effects interact to generate dome patterns. Results imply that strong top-down trophic cascades are common in freshwater communities, much more than hitherto demonstrated, and may arise in nutrient rich marine systems as well. Transferring insights from the general theory of nonlinear pattern formation to domes patterns, we provide new interpretations of past lake-manipulation experiments.},
  language  = {en}
}
@article{FranzOttenMuellerWerdanetal.2019,
  author    = {Franz, Kristina and Otten, Lindsey and M{\"u}ller-Werdan, Ursula and D{\"o}hner, Wolfram and Norman, Kristina},
  title     = {Severe Weight Loss and Its Association with Fatigue in Old Patients at Discharge from a Geriatric Hospital},
  series = {Nutrients},
  volume    = {11},
  journal   = {Nutrients},
  number    = {10},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2072-6643},
  doi       = {10.3390/nu11102415},
  pages     = {10},
  year      = {2019},
  abstract  = {Although malnutrition is frequent in the old, little is known about its association with fatigue. We evaluated the relation of self-reported severe weight loss with fatigue and the predictors for fatigue in old patients at hospital discharge. Severe weight loss was defined according to involuntary weight loss >= 5\% in the last three months. We determined fatigue with the validated Brief Fatigue Inventory questionnaire. The regression analyses were adjusted for age, sex, number of comorbidities, medications/day, and BMI. Of 424 patients aged between 61 and 98 y, 34.1\% had severe weight loss. Fatigue was higher in patients with severe weight loss (3.7 +/- 2.3 vs. 3.2 +/- 2.3 points, p = 0.021). In a multinomial regression model, weight loss was independently associated with higher risk for moderate fatigue (OR:1.172, CI:1.026-1.338, p = 0.019) and with increased risk for severe fatigue (OR:1.209, CI:1.047-1.395, p = 0.010) together with the number of medications/day (OR:1.220, CI:1.023-1.455, p = 0.027). In a binary regression model, severe weight loss predicted moderate-to-severe fatigue in the study population (OR:1.651, CI:1.052-2.590, p = 0.029). In summary, patients with self-reported severe weight loss at hospital discharge exhibited higher fatigue levels and severe weight loss was an independent predictor of moderate and severe fatigue, placing these patients at risk for impaired outcome in the post-hospital period.},
  language  = {en}
}
@article{PalyulinBlackburnLomholtetal.2019,
  author    = {Palyulin, Vladimir V. and Blackburn, George and Lomholt, Michael A. and Watkins, Nicholas W. and Metzler, Ralf and Klages, Rainer and Chechkin, Aleksei V.},
  title     = {First passage and first hitting times of Levy flights and Levy walks},
  series = {New journal of physics : the open-access journal for physics},
  volume    = {21},
  journal   = {New journal of physics : the open-access journal for physics},
  number    = {10},
  publisher = {IOP Publ. Ltd.},
  address   = {Bristol},
  issn      = {1367-2630},
  doi       = {10.1088/1367-2630/ab41bb},
  pages     = {23},
  year      = {2019},
  abstract  = {For both L{\´e}vy flight and L{\´e}vy walk search processes we analyse the full distribution of first-passage and first-hitting (or first-arrival) times. These are, respectively, the times when the particle moves across a point at some given distance from its initial position for the first time, or when it lands at a given point for the first time. For L{\´e}vy motions with their propensity for long relocation events and thus the possibility to jump across a given point in space without actually hitting it ('leapovers'), these two definitions lead to significantly different results. We study the first-passage and first-hitting time distributions as functions of the L{\´e}vy stable index, highlighting the different behaviour for the cases when the first absolute moment of the jump length distribution is finite or infinite. In particular we examine the limits of short and long times. Our results will find their application in the mathematical modelling of random search processes as well as computer algorithms.},
  language  = {en}
}
@article{MattheyDoretvanderKooiJeffriesetal.2019,
  author    = {Matthey-Doret, Cyril and van der Kooi, Casper J. and Jeffries, Daniel L. and Bast, Jens and Dennis, Alice B. and Vorburger, Christoph and Schwander, Tanja},
  title     = {Mapping of Multiple Complementary Sex Determination Loci in a Parasitoid Wasp},
  series = {Genome biology and evolution},
  volume    = {11},
  journal   = {Genome biology and evolution},
  number    = {10},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {1759-6653},
  doi       = {10.1093/gbe/evz219},
  pages     = {2954 -- 2962},
  year      = {2019},
  abstract  = {Sex determination has evolved in a variety of ways and can depend on environmental and genetic signals. A widespread form of genetic sex determination is haplodiploidy, where unfertilized, haploid eggs develop into males and fertilized diploid eggs into females. One of the molecular mechanisms underlying haplodiploidy in Hymenoptera, the large insect order comprising ants, bees, and wasps, is complementary sex determination (CSD). In species with CSD, heterozygosity at one or several loci induces female development. Here, we identify the genomic regions putatively underlying multilocus CSD in the parasitoid wasp Lysiphlebus fabarum using restriction -site associated DNA sequencing. By analyzing segregation patterns at polymorphic sites among 331 diploid males and females, we identify up to four CSD candidate regions, all on different chromosomes. None of the candidate regions feature evidence for homology with the csd gene from the honey bee, the only species in which CSD has been characterized, suggesting that CSD in L. fabarum is regulated via a novel molecular mechanism. Moreover, no homology is shared between the candidate loci, in contrast to the idea that multilocus CSD should emerge from duplications of an ancestral single -locus system. Taken together, our results suggest that the molecular mechanisms underlying CSD in Hymenoptera are not conserved between species, raising the question as to whether CSD may have evolved multiple times independently in the group.},
  language  = {en}
}
@article{FelserJessen2021,
  author    = {Felser, Claudia and Jessen, Anna},
  title     = {Correlative coordination and variable subject-verb agreement in German},
  series = {Languages : open access journal},
  volume    = {6},
  journal   = {Languages : open access journal},
  number    = {2},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2226-471X},
  doi       = {10.3390/languages6020067},
  pages     = {20},
  year      = {2021},
  abstract  = {Coordinated subjects often show variable number agreement with the finite verb, but linguistic approaches to this phenomenon have rarely been informed by systematically collected data. We report the results from three experiments investigating German speakers' agreement preferences with complex subjects joined by the correlative conjunctions sowohl horizontal ellipsis als auch ('both horizontal ellipsis and'), weder horizontal ellipsis noch ('neither horizontal ellipsis nor') or entweder horizontal ellipsis oder ('either horizontal ellipsis or'). We examine to what extent conjunction type and a conjunct's relative proximity to the verb affect the acceptability and processibility of singular vs. plural agreement. Experiment 1 was an untimed acceptability rating task, Experiment 2 a timed sentence completion task, and Experiment 3 was a self-paced reading task. Taken together, our results show that number agreement with correlative coordination in German is primarily determined by a default constraint triggering plural agreement, which interacts with linear order and semantic factors. Semantic differences between conjunctions only affected speakers' agreement preferences in the absence of processing pressure but not their initial agreement computation. The combined results from our offline and online experimental measures of German speakers' agreement preferences suggest that the constraints under investigation do not only differ in their relative weighting but also in their relative timing during agreement computation.},
  language  = {en}
}
@article{TofeldeBufeTurowski2022,
  author    = {Tofelde, Stefanie and Bufe, Aaron and Turowski, Jens M.},
  title     = {Hillslope Sediment Supply Limits Alluvial Valley Width},
  series = {AGU Advances},
  journal   = {AGU Advances},
  publisher = {American Geophysical Union (AGU); Wiley},
  address   = {Hoboken, New Jersey, USA},
  issn      = {2576-604X},
  doi       = {10.1029/2021AV000641},
  pages     = {20},
  year      = {2022},
  abstract  = {River-valley morphology preserves information on tectonic and climatic conditions that shape landscapes. Observations suggest that river discharge and valley-wall lithology are the main controls on valley width. Yet, current models based on these observations fail to explain the full range of cross-sectional valley shapes in nature, suggesting hitherto unquantified controls on valley width. In particular, current models cannot explain the existence of paired terrace sequences that form under cyclic climate forcing. Paired river terraces are staircases of abandoned floodplains on both valley sides, and hence preserve past valley widths. Their formation requires alternating phases of predominantly river incision and predominantly lateral planation, plus progressive valley narrowing. While cyclic Quaternary climate changes can explain shifts between incision and lateral erosion, the driving mechanism of valley narrowing is unknown. Here, we extract valley geometries from climatically formed, alluvial river-terrace sequences and show that across our dataset, the total cumulative terrace height (here: total valley height) explains 90\%-99\% of the variance in valley width at the terrace sites. This finding suggests that valley height, or a parameter that scales linearly with valley height, controls valley width in addition to river discharge and lithology. To explain this valley-width-height relationship, we reformulate existing valley-width models and suggest that, when adjusting to new boundary conditions, alluvial valleys evolve to a width at which sediment removal from valley walls matches lateral sediment supply from hillslope erosion. Such a hillslope-channel coupling is not captured in current valley-evolution models. Our model can explain the existence of paired terrace sequences under cyclic climate forcing and relates valley width to measurable field parameters. Therefore, it facilitates the reconstruction of past climatic and tectonic conditions from valley topography.},
  language  = {en}
}
@article{KuehnePaunovWeck2021,
  author    = {K{\"u}hne, Franziska and Paunov, Tatjana and Weck, Florian},
  title     = {Recognizing obsessive-compulsive disorder},
  series = {BMC psychiatry},
  volume    = {21},
  journal   = {BMC psychiatry},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {1471-244X},
  doi       = {10.1186/s12888-021-03458-x},
  pages     = {7},
  year      = {2021},
  abstract  = {Background Despite the prevalence of obsessive-compulsive disorder (OCD), its precise identification remains challenging. With the Zohar-Fineberg Obsessive-Compulsive Screen (ZF-OCS; 5 or 6 items), a brief instrument is widely available mainly in English. As there is a lack of empirical studies on the ZF-OCS, the aim of the present study was to translate the items into German and investigate the instrument in a nonclinical sample. Methods In two consecutive online surveys, n = 304 and n = 51 students participated. Besides the ZF-OCS, they answered established measures on OCD, depression, health anxiety, general anxiety and health-related well-being. Results Whereas internal consistency was low (α = .53-.72; ω = .55-.69), retest reliability (rt1,t2 = .89) at two weeks was high. As expected, we found high correlations with other OCD instruments (r > .61; convergent validity), and significantly weaker correlations with measures of depression (r = .39), health anxiety (r = .29), and health-related well-being (r = -.28, divergent validity). Nonetheless, the correlations with general anxiety were somewhere in between (r = .52). Conclusions Due to heterogeneous OCD subtypes, the ZF-OCS asks diverse questions which probably resulted in the present internal consistency. Nevertheless, the results on retest reliability and validity were promising. As for other OCD instruments, divergent validity regarding general anxiety seems problematic to establish. Even so, the ZF-OCS seems valuable for screening purposes, as it is short and easy to administer, and may facilitate initiating subsequent clinical assessment. Further studies should determine the instrument's diagnostic accuracy.},
  language  = {en}
}
@article{ParkStolleYamazakietal.2020,
  author    = {Park, Jaeheung and Stolle, Claudia and Yamazaki, Yosuke and Rauberg, Jan and Michaelis, Ingo and Olsen, Nils},
  title     = {Diagnosing low-/mid-latitude ionospheric currents using platform magnetometers},
  series = {Earth, planets and space},
  volume    = {72},
  journal   = {Earth, planets and space},
  number    = {1},
  publisher = {Springer},
  address   = {New York},
  issn      = {1343-8832},
  doi       = {10.1186/s40623-020-01274-3},
  pages     = {18},
  year      = {2020},
  abstract  = {Electric currents flowing in the terrestrial ionosphere have conventionally been diagnosed by low-earth-orbit (LEO) satellites equipped with science-grade magnetometers and long booms on magnetically clean satellites. In recent years, there are a variety of endeavors to incorporate platform magnetometers, which are initially designed for navigation purposes, to study ionospheric currents. Because of the suboptimal resolution and significant noise of the platform magnetometers, however, most of the studies were confined to high-latitude auroral regions, where magnetic field deflections from ionospheric currents easily exceed 100 nT. This study aims to demonstrate the possibility of diagnosing weak low-/mid-latitude ionospheric currents based on platform magnetometers. We use navigation magnetometer data from two satellites, CryoSat-2 and the Gravity Recovery and Climate Experiment Follow-On (GRACE-FO), both of which have been intensively calibrated based on housekeeping data and a high-precision geomagnetic field model. Analyses based on 8 years of CryoSat-2 data as well as similar to 1.5 years of GRACE-FO data reproduce well-known climatology of inter-hemispheric field-aligned currents (IHFACs), as reported by previous satellite missions dedicated to precise magnetic observations. Also, our results show that C-shaped structures appearing in noontime IHFAC distributions conform to the shape of the South Atlantic Anomaly. The F-region dynamo currents are only partially identified in the platform magnetometer data, possibly because the currents are weaker than IHFACs in general and depend significantly on altitude and solar activity. Still, this study evidences noontime F-region dynamo currents at the highest altitude (717 km) ever reported. We expect that further data accumulation from continuously operating missions may reveal the dynamo currents more clearly during the next solar maximum.},
  language  = {en}
}
@article{MiklashevskyFischerLindemann2022,
  author    = {Miklashevsky, Alex and Fischer, Martin H. and Lindemann, Oliver},
  title     = {Spatial-numerical associations without a motor response? Grip force says 'Yes'},
  series = {Acta Psychologica},
  volume    = {231},
  journal   = {Acta Psychologica},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-6297},
  doi       = {10.1016/j.actpsy.2022.103791},
  pages     = {1 -- 17},
  year      = {2022},
  abstract  = {In numerical processing, the functional role of Spatial-Numerical Associations (SNAs, such as the association of smaller numbers with left space and larger numbers with right space, the Mental Number Line hypothesis) is debated. Most studies demonstrate SNAs with lateralized responses, and there is little evidence that SNAs appear when no response is required. We recorded passive holding grip forces in no-go trials during number processing. In Experiment 1, participants performed a surface numerical decision task ("Is it a number or a letter?"). In Experiment 2, we used a deeper semantic task ("Is this number larger or smaller than five?"). Despite instruction to keep their grip force constant, participants' spontaneous grip force changed in both experiments: Smaller numbers led to larger force increase in the left than in the right hand in the numerical decision task (500-700 ms after stimulus onset). In the semantic task, smaller numbers again led to larger force increase in the left hand, and larger numbers increased the right-hand holding force. This effect appeared earlier (180 ms) and lasted longer (until 580 ms after stimulus onset). This is the first demonstration of SNAs with passive holding force. Our result suggests that (1) explicit motor response is not a prerequisite for SNAs to appear, and (2) the timing and strength of SNAs are task-dependent. (216 words).},
  language  = {en}
}
@article{DragoPawlakWeithoff2020,
  author    = {Drago, Claudia and Pawlak, Julia and Weithoff, Guntram},
  title     = {Biogenic aggregation of small microplastics alters their ingestion by a common freshwater micro-invertebrate},
  series = {Frontiers in Environmental Science},
  volume    = {8},
  journal   = {Frontiers in Environmental Science},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-665X},
  doi       = {10.3389/fenvs.2020.574274},
  pages     = {11},
  year      = {2020},
  abstract  = {In recent years, increasing concerns have been raised about the environmental risk of microplastics in freshwater ecosystems. Small microplastics enter the water either directly or accumulate through disintegration of larger plastic particles. These particles might then be ingested by filter-feeding zooplankton, such as rotifers. Particles released into the water may also interact with the biota through the formation of aggregates, which might alter the uptake by zooplankton. In this study, we tested for size-specific aggregation of polystyrene microspheres and their ingestion by a common freshwater rotifer Brachionus calyciflorus. The ingestion of three sizes of polystyrene microspheres (MS) 1-, 3-, and 6-mu m was investigated. Each MS size was tested in combination with three different treatments: MS as the sole food intake, MS in association with food algae and MS aggregated with biogenic matter. After 72 h incubation in pre-filtered natural river water, the majority of the 1-mu m spheres occurred as aggregates. The larger the particles, the higher the relative number of single particles and the larger the aggregates. All particles were ingested by the rotifer following a Type-II functional response. The presence of algae did not influence the ingestion of the MS for all three sizes. The biogenic aggregation of microspheres led to a significant size-dependent alteration in their ingestion. Rotifers ingested more microspheres (MS) when exposed to aggregated 1- and 3-mu m MS as compared to single spheres, whereas fewer aggregated 6-mu m spheres were ingested. This indicates that the small particles when aggregated were in an effective size range for Brachionus, while the aggregated larger spheres became too large to be efficiently ingested. These observations provide the first evidence of a size- and aggregation-dependent feeding interaction between microplastics and rotifers. Microplastics when aggregated with biogenic particles in a natural environment can rapidly change their size-dependent availability. The aggregation properties of microplastics should be taken into account when performing experiments mimicking the natural environment.},
  language  = {en}
}
@article{LindnerMoellerHildebrandtetal.2022,
  author    = {Lindner, Nadja and Moeller, Korbinian and Hildebrandt, Frauke and Hasselhorn, Marcus and Lonnemann, Jan},
  title     = {Children's use of egocentric reference frames in spatial language is related to their numerical magnitude understanding},
  series = {Frontiers in Psychology},
  journal   = {Frontiers in Psychology},
  publisher = {Frontiers},
  address   = {Lausanne, Schweiz},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2022.943191},
  pages     = {1 -- 13},
  year      = {2022},
  abstract  = {Numerical magnitude information is assumed to be spatially represented in the form of a mental number line defined with respect to a body-centred, egocentric frame of reference. In this context, spatial language skills such as mastery of verbal descriptions of spatial position (e.g., in front of, behind, to the right/left) have been proposed to be relevant for grasping spatial relations between numerical magnitudes on the mental number line. We examined 4- to 5-year-old's spatial language skills in tasks that allow responses in egocentric and allocentric frames of reference, as well as their relative understanding of numerical magnitude (assessed by a number word comparison task). In addition, we evaluated influences of children's absolute understanding of numerical magnitude assessed by their number word comprehension (montring different numbers using their fingers) and of their knowledge on numerical sequences (determining predecessors and successors as well as identifying missing dice patterns of a series). Results indicated that when considering responses that corresponded to the egocentric perspective, children's spatial language was associated significantly with their relative numerical magnitude understanding, even after controlling for covariates, such as children's SES, mental rotation skills, and also absolute magnitude understanding or knowledge on numerical sequences. This suggests that the use of egocentric reference frames in spatial language may facilitate spatial representation of numbers along a mental number line and thus seem important for preschoolers' relative understanding of numerical magnitude.},
  language  = {en}
}
@article{OgunkolaGuiraudieCaprazFeronetal.2023,
  author    = {Ogunkola, Moses Olalekan and Guiraudie-Capraz, Gaelle and F{\´e}ron, Fran{\c{c}}ois and Leimk{\"u}hler, Silke},
  title     = {The Human Mercaptopyruvate Sulfurtransferase TUM1 Is Involved in Moco Biosynthesis, Cytosolic tRNA Thiolation and Cellular Bioenergetics in Human Embryonic Kidney Cells},
  series = {Biomolecules},
  volume    = {13},
  journal   = {Biomolecules},
  edition   = {1},
  publisher = {MDPI},
  address   = {Basel, Schweiz},
  issn      = {2218-273X},
  doi       = {10.3390/biom13010144},
  pages     = {1 -- 23},
  year      = {2023},
  abstract  = {Sulfur is an important element that is incorporated into many biomolecules in humans. The incorporation and transfer of sulfur into biomolecules is, however, facilitated by a series of different sulfurtransferases. Among these sulfurtransferases is the human mercaptopyruvate sulfurtransferase (MPST) also designated as tRNA thiouridine modification protein (TUM1). The role of the human TUM1 protein has been suggested in a wide range of physiological processes in the cell among which are but not limited to involvement in Molybdenum cofactor (Moco) biosynthesis, cytosolic tRNA thiolation and generation of H2S as signaling molecule both in mitochondria and the cytosol. Previous interaction studies showed that TUM1 interacts with the L-cysteine desulfurase NFS1 and the Molybdenum cofactor biosynthesis protein 3 (MOCS3). Here, we show the roles of TUM1 in human cells using CRISPR/Cas9 genetically modified Human Embryonic Kidney cells. Here, we show that TUM1 is involved in the sulfur transfer for Molybdenum cofactor synthesis and tRNA thiomodification by spectrophotometric measurement of the activity of sulfite oxidase and liquid chromatography quantification of the level of sulfur-modified tRNA. Further, we show that TUM1 has a role in hydrogen sulfide production and cellular bioenergetics.},
  language  = {en}
}
@book{BenderDreiackEngelsetal.2022,
  author    = {Bender, Carsten and Dreiack, Stefanie and Engels, Victoria and Fisseler, Bj{\"o}rn and Gregory, Luisa and Gross, Monika and Kaffenberger, Jens and Kost{\"a}dt, Peter and Meyer zu Bexten, Erdmuthe and Rustemeier, Linda and Schwarz, Thorsten and Tannert, Benjamin and Velasquez, Estefania Cepeda and Weber, Gerhard},
  title     = {Leitfaden zur Digitalen Barrierefreiheit im Hochschulkontext},
  series = {Arbeitspapier / Hochschulforum Digitalisierung (HFD) ; 66},
  volume    = {5},
  journal   = {Arbeitspapier / Hochschulforum Digitalisierung (HFD) ; 66},
  publisher = {Stifterverband f{\"u}r die Deutsche Wissenschaft},
  address   = {Berlin},
  issn      = {2365-7081},
  doi       = {10.5445/IR/1000153177},
  pages     = {43},
  year      = {2022},
  language  = {de}
}
@article{BertelmannMittermaierKostaedt2022,
  author    = {Bertelmann, Roland and Mittermaier, Bernhard and Kost{\"a}dt, Peter},
  title     = {Transform2Open},
  publisher = {Helmholtz Open Science Office},
  address   = {Potsdam},
  doi       = {10.48440/os.helmholtz.054},
  pages     = {22},
  year      = {2022},
  language  = {de}
}
@article{RezoriBuchallikWarschburger2022,
  author    = {Rezori, Roman Enzio von and Buchallik, Friederike and Warschburger, Petra},
  title     = {Validation of the German Benefit Finding Scale for youth with chronic conditions},
  series = {Child and adolescent psychiatry and mental health},
  volume    = {16},
  journal   = {Child and adolescent psychiatry and mental health},
  publisher = {Biomed Central},
  address   = {London},
  issn      = {1753-2000},
  doi       = {10.1186/s13034-021-00438-7},
  pages     = {1 -- 8},
  year      = {2022},
  abstract  = {Background Benefit finding, defined as perceiving positive life changes resulting from adversity and negative life stressors, gains growing attention in the context of chronic illness. The study aimed at examining the psychometric properties of the Benefit Finding Scale for Children (BFSC) in a sample of German youth facing chronic conditions. Methods A sample of adolescents with various chronic conditions (N = 304; 12 - 21years) completed the 10-item BFSC along with measures of intra- and interpersonal resources, coping strategies, and health-related quality of life (hrQoL). The total sample was randomly divided into two subsamples for conducting exploratory and confirmatory factor analyses (EFA/CFA). Results EFA revealed that the BFSC scores had a one-dimensional factor structure. CFA verified the one-dimensional factor structure with an acceptable fit. The BFSC exhibited acceptable internal consistency (α = 0.87 - 0.88) and construct validity. In line with our hypotheses, benefit finding was positively correlated with optimism, self-esteem, self-efficacy, sense of coherence, and support seeking. There were no correlations with avoidance, wishful thinking, emotional reaction, and hrQoL. Sex differences in benefit finding were not consistent across subsamples. Benefit finding was also positively associated with age, disease severity, and social status. Conclusions The BFSC is a psychometrically sound instrument to assess benefit finding in adolescents with chronic illness and may facilitate further research on positive adaptation processes in adolescents, irrespective of their specific diagnosis.},
  language  = {en}
}
@article{MarggrafLindeckeVoigtetal.2023,
  author    = {Marggraf, Lara Christin and Lindecke, Oliver and Voigt, Christian C. and Pētersons, Gunārs and Voigt-Heucke, Silke Luise},
  title     = {Nathusius' bats, Pipistrellus nathusii, bypass mating opportunities of their own species, but respond to foraging heterospecifics on migratory transit flights},
  series = {Frontiers in Ecology and Evolution},
  journal   = {Frontiers in Ecology and Evolution},
  publisher = {Frontiers},
  address   = {Lausanne, Schweiz},
  issn      = {2296-701X},
  doi       = {10.3389/fevo.2022.908560},
  pages     = {1 -- 10},
  year      = {2023},
  abstract  = {In late summer, migratory bats of the temperate zone face the challenge of accomplishing two energy-demanding tasks almost at the same time: migration and mating. Both require information and involve search efforts, such as localizing prey or finding potential mates. In non-migrating bat species, playback studies showed that listening to vocalizations of other bats, both con-and heterospecifics, may help a recipient bat to find foraging patches and mating sites. However, we are still unaware of the degree to which migrating bats depend on con-or heterospecific vocalizations for identifying potential feeding or mating opportunities during nightly transit flights. Here, we investigated the vocal responses of Nathusius' pipistrelle bats, Pipistrellus nathusii, to simulated feeding and courtship aggregations at a coastal migration corridor. We presented migrating bats either feeding buzzes or courtship calls of their own or a heterospecific migratory species, the common noctule, Nyctalus noctula. We expected that during migratory transit flights, simulated feeding opportunities would be particularly attractive to bats, as well as simulated mating opportunities which may indicate suitable roosts for a stopover. However, we found that when compared to the natural silence of both pre-and post-playback phases, bats called indifferently during the playback of conspecific feeding sounds, whereas P. nathusii echolocation call activity increased during simulated feeding of N. noctula. In contrast, the call activity of P. nathusii decreased during the playback of conspecific courtship calls, while no response could be detected when heterospecific call types were broadcasted. Our results suggest that while on migratory transits, P. nathusii circumnavigate conspecific mating aggregations, possibly to save time or to reduce the risks associated with social interactions where aggression due to territoriality might be expected. This avoidance behavior could be a result of optimization strategies by P. nathusii when performing long-distance migratory flights, and it could also explain the lack of a response to simulated conspecific feeding. However, the observed increase of activity in response to simulated feeding of N. noctula, suggests that P. nathusii individuals may be eavesdropping on other aerial hawking insectivorous species during migration, especially if these occupy a slightly different foraging niche.},
  language  = {en}
}
@article{Doerfler2018,
  author    = {D{\"o}rfler, Thomas},
  title     = {Die Sanktionsaussch{\"u}sse zwischen Macht und Regeln},
  series = {Vereinte Nationen : Zeitschrift f{\"u}r die Vereinten Nationen und ihre Sonderorganisationen},
  volume    = {66},
  journal   = {Vereinte Nationen : Zeitschrift f{\"u}r die Vereinten Nationen und ihre Sonderorganisationen},
  number    = {2},
  publisher = {BWV},
  address   = {Berlin},
  issn      = {0042-384X},
  pages     = {62 -- 66},
  year      = {2018},
  abstract  = {Sanktionen sind ein wichtiges Instrument des UN-Sicherheitsrats zur Erhaltung des Weltfriedens. Viele zentrale Entscheidungen, wie etwa die Listung und Entlistung terrorverd{\"a}chtiger Personen, werden fernab der {\"O}ffentlichkeit in Sanktionsaussch{\"u}ssen getroffen. Die Einsetzung dieser Aussch{\"u}sse hat die Entscheidungsdynamiken im Rat erheblich ver{\"a}ndert.},
  language  = {de}
}
@article{KuehneFauthDestinaSevdeetal.2021,
  author    = {K{\"u}hne, Franziska and Fauth, Henriette and Destina Sevde, Ay-Bryson and Visser, Leonie N.C. and Weck, Florian},
  title     = {Communicating the diagnosis of cancer or depression: Results of a randomized controlled online study using video vignettes},
  series = {Cancer Medicine},
  volume    = {10},
  journal   = {Cancer Medicine},
  edition   = {24},
  publisher = {Wiley},
  address   = {Hoboken, New Jersey, USA},
  issn      = {2045-7634},
  doi       = {10.1002/cam4.4396},
  pages     = {9012 -- 9021},
  year      = {2021},
  abstract  = {Background Communicating a diagnosis is highly important, yet complex, especially in the context of cancer and mental disorders. The aim was to explore the communication style of an oncologist vs. psychotherapist in an online study. Methods Patients (N = 136: 65 cancer, 71 depression) were randomly assigned to watch a standardized video vignette with one of two communication styles (empathic vs. unempathic). Outcome measures of affectivity, information recall, communication skills, empathy and trust were applied. Results Regardless of diagnosis, empathic communication was associated with the perception of a significantly more empathic (p < 0.001, η2partial = 0.08) and trustworthy practitioner (p = 0.014, η2partial = 0.04) with better communication skills (p = 0.013, η2partial = 0.05). Cancer patients reported a larger decrease in positive affect (p < 0.001, η2partial = 0.15) and a larger increase in negative affect (p < 0.001, η2partial = 0.14) from pre- to post-video than depressive patients. Highly relevant information was recalled better in both groups (p < 0.001, d = 0.61-1.06). Conclusions The results highlight the importance of empathy while communicating both a diagnosis of cancer and a mental disorder. Further research should focus on the communication of a mental disorder in association with cancer.},
  language  = {en}
}
@article{WojcikCeulemansGaedke2021,
  author    = {Wojcik, Laurie Anne and Ceulemans, Ruben and Gaedke, Ursula},
  title     = {Functional diversity buffers the effects of a pulse perturbation on the dynamics of tritrophic food webs},
  series = {Ecology and Evolution},
  volume    = {11},
  journal   = {Ecology and Evolution},
  number    = {22},
  publisher = {John Wiley \& Sons, Inc.},
  address   = {Hoboken (New Jersey)},
  issn      = {2045-7758},
  doi       = {10.1002/ece3.8214},
  pages     = {15639 -- 15663},
  year      = {2021},
  abstract  = {Biodiversity decline causes a loss of functional diversity, which threatens ecosystems through a dangerous feedback loop: This loss may hamper ecosystems' ability to buffer environmental changes, leading to further biodiversity losses. In this context, the increasing frequency of human-induced excessive loading of nutrients causes major problems in aquatic systems. Previous studies investigating how functional diversity influences the response of food webs to disturbances have mainly considered systems with at most two functionally diverse trophic levels. We investigated the effects of functional diversity on the robustness, that is, resistance, resilience, and elasticity, using a tritrophic—and thus more realistic—plankton food web model. We compared a non-adaptive food chain with no diversity within the individual trophic levels to a more diverse food web with three adaptive trophic levels. The species fitness differences were balanced through trade-offs between defense/growth rate for prey and selectivity/half-saturation constant for predators. We showed that the resistance, resilience, and elasticity of tritrophic food webs decreased with larger perturbation sizes and depended on the state of the system when the perturbation occurred. Importantly, we found that a more diverse food web was generally more resistant and resilient but its elasticity was context-dependent. Particularly, functional diversity reduced the probability of a regime shift toward a non-desirable alternative state. The basal-intermediate interaction consistently determined the robustness against a nutrient pulse despite the complex influence of the shape and type of the dynamical attractors. This relationship was strongly influenced by the diversity present and the third trophic level. Overall, using a food web model of realistic complexity, this study confirms the destructive potential of the positive feedback loop between biodiversity loss and robustness, by uncovering mechanisms leading to a decrease in resistance, resilience, and potentially elasticity as functional diversity declines.},
  language  = {en}
}
@article{Minnes2020,
  author    = {Minnes, Mark},
  title     = {M{\´a}s all{\´a} de la oscuridad},
  series = {RILCE : revista de filolog{\´i}a hisp{\´a}nica obalizaci{\´o}n moderna},
  volume    = {36},
  journal   = {RILCE : revista de filolog{\´i}a hisp{\´a}nica obalizaci{\´o}n moderna},
  number    = {1},
  publisher = {Ediciones Universidad de Navarra},
  address   = {Pamplona},
  issn      = {0213-2370},
  doi       = {10.15581/008.36.1.387-406},
  pages     = {387 -- 406},
  year      = {2020},
  abstract  = {En los {\´u}ltimos a{\~n}os, la cr{\´i}tica ha vuelto a enfatizar el v{\´i}nculo de la escritura gongorina la {\´e}pica y los subg{\´e}neros denominados "heroicos" (Mercedes Blanco, Jes{\´u}s Ponce C{\´a}rdenas). Esta nueva perspectiva significa un cambio importante respecto a la recepci{\´o}n del poeta instaurada por la Generaci{\´o}n del 27 y en particular por D{\´a}maso Alonso. Limit{\´a}ndose a las Soledades de G{\´o}ngora, el presente art{\´i}culo explora las consecuencias de este nuevo paradigma, m{\´a}s all{\´a} de un G{\´o}ngora puramente l{\´i}rico. Metodol{\´o}gicamente, proponemos dejar atr{\´a}s la dial{\´e}ctica idealista o marxista de forma-contenido (la ideolog{\´i}a de la forma de Fredric Jameson), por considerarla un enfoque anacr{\´o}nico en el caso de G{\´o}ngora. Sin embargo, encontramos un acercamiento filol{\´o}gico viable en el compromiso de la forma del temprano Barthes, que trata de esquivar la dial{\´e}ctica de forma-contenido y volver a un gesto de escritura ({\´e}criture). La hip{\´o}tesis del presente art{\´i}culo ser{\´i}a, pues, que no se ha reflexionado suficientemente sobre el gesto de la escritura gongorina en las Soledades: una escritura que piratea el lenguaje {\´e}pico.},
  language  = {es}
}
@article{EndesfelderWeicheltStraussetal.2017,
  author    = {Endesfelder, Stefanie and Weichelt, Ulrike and Strauß, Evelyn and Schl{\"o}r, Anja and Sifringer, Marco and Scheuer, Till and B{\"u}hrer, Christoph and Schmitz, Thomas},
  title     = {Neuroprotection by caffeine in hyperoxia-induced neonatal brain injury},
  series = {International journal of molecular sciences},
  volume    = {18},
  journal   = {International journal of molecular sciences},
  publisher = {Molecular Diversity Preservation International},
  address   = {Basel},
  issn      = {1422-0067},
  doi       = {10.3390/ijms18010187},
  pages     = {24},
  year      = {2017},
  abstract  = {Sequelae of prematurity triggered by oxidative stress and free radical-mediated tissue damage have coined the term "oxygen radical disease of prematurity". Caffeine, a potent free radical scavenger and adenosine receptor antagonist, reduces rates of brain damage in preterm infants. In the present study, we investigated the effects of caffeine on oxidative stress markers, anti-oxidative response, inflammation, redox-sensitive transcription factors, apoptosis, and extracellular matrix following the induction of hyperoxia in neonatal rats. The brain of a rat pups at postnatal Day 6 (P6) corresponds to that of a human fetal brain at 28-32 weeks gestation and the neonatal rat is an ideal model in which to investigate effects of oxidative stress and neuroprotection of caffeine on the developing brain. Six-day-old Wistar rats were pre-treated with caffeine and exposed to 80\% oxygen for 24 and 48 h. Caffeine reduced oxidative stress marker (heme oxygenase-1, lipid peroxidation, hydrogen peroxide, and glutamate-cysteine ligase catalytic subunit (GCLC)), promoted anti-oxidative response (superoxide dismutase, peroxiredoxin 1, and sulfiredoxin 1), down-regulated pro-inflammatory cytokines, modulated redox-sensitive transcription factor expression (Nrf2/Keap1, and NFκB), reduced pro-apoptotic effectors (poly (ADP-ribose) polymerase-1 (PARP-1), apoptosis inducing factor (AIF), and caspase-3), and diminished extracellular matrix degeneration (matrix metalloproteinases (MMP) 2, and inhibitor of metalloproteinase (TIMP) 1/2). Our study affirms that caffeine is a pleiotropic neuroprotective drug in the developing brain due to its anti-oxidant, anti-inflammatory, and anti-apoptotic properties.},
  language  = {en}
}
@article{ReegStriglJeltsch2022,
  author    = {Reeg, Jette and Strigl, Lea and Jeltsch, Florian},
  title     = {Agricultural buffer zone thresholds to safeguard functional bee diversity},
  series = {Ecology and Evolution},
  volume    = {12},
  journal   = {Ecology and Evolution},
  edition   = {3},
  publisher = {Wiley Online Library},
  address   = {Hoboken, New Jersey, USA},
  issn      = {2045-7758},
  doi       = {10.1002/ece3.8748},
  pages     = {1 -- 17},
  year      = {2022},
  abstract  = {Wild bee species are important pollinators in agricultural landscapes. However, population decline was reported over the last decades and is still ongoing. While agricultural intensification is a major driver of the rapid loss of pollinating species, transition zones between arable fields and forest or grassland patches, i.e., agricultural buffer zones, are frequently mentioned as suitable mitigation measures to support wild bee populations and other pollinator species. Despite the reported general positive effect, it remains unclear which amount of buffer zones is needed to ensure a sustainable and permanent impact for enhancing bee diversity and abundance. To address this question at a pollinator community level, we implemented a process-based, spatially explicit simulation model of functional bee diversity dynamics in an agricultural landscape. More specifically, we introduced a variable amount of agricultural buffer zones (ABZs) at the transition of arable to grassland, or arable to forest patches to analyze the impact on bee functional diversity and functional richness. We focused our study on solitary bees in a typical agricultural area in the Northeast of Germany. Our results showed positive effects with at least 25\% of virtually implemented agricultural buffer zones. However, higher amounts of ABZs of at least 75\% should be considered to ensure a sufficient increase in Shannon diversity and decrease in quasi-extinction risks. These high amounts of ABZs represent effective conservation measures to safeguard the stability of pollination services provided by solitary bee species. As the model structure can be easily adapted to other mobile species in agricultural landscapes, our community approach offers the chance to compare the effectiveness of conservation measures also for other pollinator communities in future.},
  language  = {en}
}
@article{KaunathEccard2022,
  author    = {Kaunath, Vera and Eccard, Jana},
  title     = {Light Attraction in Carabid Beetles},
  series = {Frontiers in Ecology and Evolution},
  volume    = {10},
  journal   = {Frontiers in Ecology and Evolution},
  publisher = {Frontiers Media},
  address   = {Lausanne, Schweiz},
  issn      = {2296-701X},
  doi       = {10.3389/fevo.2022.751288},
  pages     = {10},
  year      = {2022},
  abstract  = {Artificial light at night (ALAN) is altering the behaviour of nocturnal animals in a manifold of ways. Nocturnal invertebrates are particularly affected, due to their fatal attraction to ALAN. This selective pressure has the potential to reduce the strength of the flight-to-light response in insects, as shown recently in a moth species. Here we investigated light attraction of ground beetles (Coleoptera: Carabidae).We compared among animals (three genera) from a highly light polluted (HLP) grassland in the centre of Berlin and animals collected at a low-polluted area in a Dark Sky Reserve (DSR), captured using odour bait. In an arena setting tested at night time, HLP beetles (n = 75 across all genera) showed a reduced attraction towards ALAN. Tested during daytime, HLP beetles were less active in an open field test (measured as latency to start moving), compared to DSR (n = 143). However, we did not observe a reduced attraction towards ALAN within the species most common at both sides, Calathus fuscipes (HLP = 37, DSR = 118 individuals) indicating that not all species may be equally affected by ALAN. Reduced attraction to ALAN in urban beetles may either be a result of phenotypic selection in each generation removing HLP individuals that are attracted to light, or an indication for ongoing evolutionary differentiation among city and rural populations in their light response. Reduced attraction to light sources may directly enhance survival and reproductive success of urban individuals. However, decrease in mobility may negatively influence dispersal, reproduction and foraging success, highlighting the selective pressure that light pollution may have on fitness, by shaping and modifying the behaviour of insects.},
  language  = {en}
}
@article{Faber2015,
  author    = {Faber, Eike},
  title     = {Zweimal Kyros},
  series = {Potestas : revista de estudios del mundo cl{\´a}sico e historia del arte},
  journal   = {Potestas : revista de estudios del mundo cl{\´a}sico e historia del arte},
  number    = {8},
  publisher = {Universitat Jaume I},
  address   = {Castell{\´o}n},
  issn      = {1888-9867},
  doi       = {10.6035/potestas.2015.8.2},
  pages     = {37 -- 56},
  year      = {2015},
  abstract  = {«Kyros» taucht als F{\"u}rstenname dreimal in der {\"U}berlieferung des Perserreiches auf. Der Historiker Xenophon von Athen (427-ca. 355 v. Chr.) hat in seinen Schriften {\"u}ber zwei Tr{\"a}ger dieses Namens berichtet und sie durchaus unterschiedlich bewertet: Kyros II. («der Große»), Mehrer des Reiches, sowie ein Jahrhundert sp{\"a}ter Kyros, Sohn des Dareios und j{\"u}ngerer Bruder des Perserk{\"o}nigs Artaxerxes II. Der {\"a}ltere Kyros ist namengebender Protagonist eines F{\"u}rstenspiegels (der Kyrop{\"a}die), wird also grunds{\"a}tzlich positiv und als ein Vorbild f{\"u}r andere dargestellt. Am erfolglosen Kampf des j{\"u}ngeren Kyros um die Krone des Perserreichs hatte Xenophon als Offizier griechischer S{\"o}ldner selbst teilgenommen. Aus dem Vergleich von Darstellung und Bewertung der beiden F{\"u}rsten lassen sich die Anspr{\"u}che Xenophons an einen idealen Herrscher ableiten, was hier unternommen werden soll. Zugleich erm{\"o}glichen diese Ergebnisse, Xenophon als Historiker und politischen Denker in der zeitgen{\"o}ssischen Debatte um die beste Staatsform einzubetten.},
  language  = {de}
}
@article{Faber2009,
  author    = {Faber, Eike},
  title     = {Macht der Rhetorik - Rhetorik der Macht},
  series = {Potestas : revista de estudios del mundo cl{\´a}sico e historia del arte},
  volume    = {2},
  journal   = {Potestas : revista de estudios del mundo cl{\´a}sico e historia del arte},
  number    = {2},
  publisher = {Universitat Jaume},
  address   = {Castell{\´o}n},
  issn      = {1888-9867},
  pages     = {117 -- 132},
  year      = {2009},
  abstract  = {ie athenische Totenrede (epitaphios logos) spielte eine Schl{\"u}sselrolle bei der Konstruktion des idealisierten Selbstbildes des demokratischen Athen (5./4. Jh.v.Chr.). Dieser Aufsatz zeigt auf, dass die beiden bekanntesten Beispiele f{\"u}r das rhetorische Genre, die Rede des Perikes auf die Gefallenen bei Thukydides und die Rede des Sokrates im platonischen Dialog Menexenos, tats{\"a}chlich scharfe Kritik an der Instituton der Totenrede und an der demokratischen Polis an sich {\"u}ben, obwohl beide Texte f{\"u}r sich betrachtet gemeinhin als affirmativ verstanden werden.},
  language  = {de}
}
@article{KaiserBrenne2022,
  author    = {Kaiser, Michaela and Brenne, Andreas},
  title     = {{\"A}sthetik - Normativit{\"a}t - Diversit{\"a}t},
  series = {Individuelle F{\"o}rderung - Heterogenit{\"a}t und Handlungsperspektiven in der Schule},
  journal   = {Individuelle F{\"o}rderung - Heterogenit{\"a}t und Handlungsperspektiven in der Schule},
  publisher = {Waxmann},
  address   = {Stuttgart},
  isbn      = {978-3-8385-5919-3},
  doi       = {10.36198/9783838559193},
  pages     = {249 -- 259},
  year      = {2022},
  language  = {de}
}
@article{LiebeDordevicKaufmannetal.2022,
  author    = {Liebe, Thomas and Dordevic, Milos and Kaufmann, J{\"o}rn and Avetisyan, Araks and Skalej, Martin and M{\"u}ller, Notger Germar},
  title     = {Investigation of the functional pathogenesis of mild cognitive impairment by localisation-based locus coeruleus resting-state fMRI},
  series = {Human Brain Mapping},
  volume    = {43},
  journal   = {Human Brain Mapping},
  edition   = {18},
  publisher = {Wiley},
  address   = {New York, NY, USA},
  issn      = {1097-0193},
  doi       = {10.1002/hbm.26039},
  pages     = {5630 -- 5642},
  year      = {2022},
  abstract  = {Dementia as one of the most prevalent diseases urges for a better understanding of the central mechanisms responsible for clinical symptoms, and necessitates improvement of actual diagnostic capabilities. The brainstem nucleus locus coeruleus (LC) is a promising target for early diagnosis because of its early structural alterations and its relationship to the functional disturbances in the patients. In this study, we applied our improved method of localisation-based LC resting-state fMRI to investigate the differences in central sensory signal processing when comparing functional connectivity (fc) of a patient group with mild cognitive impairment (MCI, n = 28) and an age-matched healthy control group (n = 29). MCI and control participants could be differentiated in their Mini-Mental-State-Examination (MMSE) scores (p < .001) and LC intensity ratio (p = .010). In the fMRI, LC fc to anterior cingulate cortex (FDR p < .001) and left anterior insula (FDR p = .012) was elevated, and LC fc to right temporoparietal junction (rTPJ, FDR p = .012) and posterior cingulate cortex (PCC, FDR p = .021) was decreased in the patient group. Importantly, LC to rTPJ connectivity was also positively correlated to MMSE scores in MCI patients (p = .017). Furthermore, we found a hyperactivation of the left-insula salience network in the MCI patients. Our results and our proposed disease model shed new light on the functional pathogenesis of MCI by directing to attentional network disturbances, which could aid new therapeutic strategies and provide a marker for diagnosis and prediction of disease progression.},
  language  = {en}
}
@article{HauffeRathAgyapongetal.2022,
  author    = {Hauffe, Robert and Rath, Michaela and Agyapong, Wilson and Jonas, Wenke and Vogel, Heike and Schulz, Tim Julius and Schwarz, Maria and Kipp, Anna Patricia and Bl{\"u}her, Matthias and Kleinridders, Andr{\´e}},
  title     = {Obesity Hinders the Protective Effect of Selenite Supplementation on Insulin Signaling},
  series = {Antioxidants},
  volume    = {11},
  journal   = {Antioxidants},
  edition   = {5},
  publisher = {MDPI},
  address   = {Basel, Schweiz},
  issn      = {2076-3921},
  doi       = {10.3390/antiox11050862},
  pages     = {1 -- 16},
  year      = {2022},
  abstract  = {The intake of high-fat diets (HFDs) containing large amounts of saturated long-chain fatty acids leads to obesity, oxidative stress, inflammation, and insulin resistance. The trace element selenium, as a crucial part of antioxidative selenoproteins, can protect against the development of diet-induced insulin resistance in white adipose tissue (WAT) by increasing glutathione peroxidase 3 (GPx3) and insulin receptor (IR) expression. Whether selenite (Se) can attenuate insulin resistance in established lipotoxic and obese conditions is unclear. We confirm that GPX3 mRNA expression in adipose tissue correlates with BMI in humans. Cultivating 3T3-L1 pre-adipocytes in palmitate-containing medium followed by Se treatment attenuates insulin resistance with enhanced GPx3 and IR expression and adipocyte differentiation. However, feeding obese mice a selenium-enriched high-fat diet (SRHFD) only resulted in a modest increase in overall selenoprotein gene expression in WAT in mice with unaltered body weight development, glucose tolerance, and insulin resistance. While Se supplementation improved adipocyte morphology, it did not alter WAT insulin sensitivity. However, mice fed a SRHFD exhibited increased insulin content in the pancreas. Overall, while selenite protects against palmitate-induced insulin resistance in vitro, obesity impedes the effect of selenite on insulin action and adipose tissue metabolism in vivo.},
  language  = {en}
}
@article{OttoMareljaSchoofsetal.2018,
  author    = {Otto, Nils and Marelja, Zvonimir and Schoofs, Andreas and Kranenburg, Holger and Bittern, Jonas and Yildirim, Kerem and Berh, Dimitri and Bethke, Maria and Thomas, Silke and Rode, Sandra and Risse, Benjamin and Jiang, Xiaoyi and Pankratz, Michael and Leimk{\"u}hler, Silke and Kl{\"a}mbt, Christian},
  title     = {The sulfite oxidase Shopper controls neuronal activity by regulating glutamate homeostasis in Drosophila ensheathing glia},
  series = {Nature Communications},
  volume    = {9},
  journal   = {Nature Communications},
  publisher = {Nature Publ. Group},
  address   = {London},
  issn      = {2041-1723},
  doi       = {10.1038/s41467-018-05645-z},
  pages     = {12},
  year      = {2018},
  abstract  = {Specialized glial subtypes provide support to developing and functioning neural networks. Astrocytes modulate information processing by neurotransmitter recycling and release of neuromodulatory substances, whereas ensheathing glial cells have not been associated with neuromodulatory functions yet. To decipher a possible role of ensheathing glia in neuronal information processing, we screened for glial genes required in the Drosophila central nervous system for normal locomotor behavior. Shopper encodes a mitochondrial sulfite oxidase that is specifically required in ensheathing glia to regulate head bending and peristalsis. shopper mutants show elevated sulfite levels affecting the glutamate homeostasis which then act on neuronal network function. Interestingly, human patients lacking the Shopper homolog SUOX develop neurological symptoms, including seizures. Given an enhanced expression of SUOX by oligodendrocytes, our findings might indicate that in both invertebrates and vertebrates more than one glial cell type may be involved in modulating neuronal activity.},
  language  = {en}
}
@misc{KrsticReinischSchuppetal.2018,
  author    = {Krstic, Jelena and Reinisch, Isabel and Schupp, Michael and Schulz, Tim Julius and Prokesch, Andreas},
  title     = {p53 functions in adipose tissue metabolism and homeostasis},
  series = {International journal of molecular sciences},
  volume    = {19},
  journal   = {International journal of molecular sciences},
  number    = {9},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1422-0067},
  doi       = {10.3390/ijms19092622},
  pages     = {21},
  year      = {2018},
  abstract  = {As a tumor suppressor and the most frequently mutated gene in cancer, p53 is among the best-described molecules in medical research. As cancer is in most cases an age-related disease, it seems paradoxical that p53 is so strongly conserved from early multicellular organisms to humans. A function not directly related to tumor suppression, such as the regulation of metabolism in nontransformed cells, could explain this selective pressure. While this role of p53 in cellular metabolism is gradually emerging, it is imperative to dissect the tissue-and cell-specific actions of p53 and its downstream signaling pathways. In this review, we focus on studies reporting p53's impact on adipocyte development, function, and maintenance, as well as the causes and consequences of altered p53 levels in white and brown adipose tissue (AT) with respect to systemic energy homeostasis. While whole body p53 knockout mice gain less weight and fat mass under a high-fat diet owing to increased energy expenditure, modifying p53 expression specifically in adipocytes yields more refined insights: (1) p53 is a negative regulator of in vitro adipogenesis; (2) p53 levels in white AT are increased in diet-induced and genetic obesity mouse models and in obese humans; (3) functionally, elevated p53 in white AT increases senescence and chronic inflammation, aggravating systemic insulin resistance; (4) p53 is not required for normal development of brown AT; and (5) when p53 is activated in brown AT in mice fed a high-fat diet, it increases brown AT temperature and brown AT marker gene expression, thereby contributing to reduced fat mass accumulation. In addition, p53 is increasingly being recognized as crucial player in nutrient sensing pathways. Hence, despite existence of contradictory findings and a varying density of evidence, several functions of p53 in adipocytes and ATs have been emerging, positioning p53 as an essential regulatory hub in ATs. Future studies need to make use of more sophisticated in vivo model systems and should identify an AT-specific set of p53 target genes and downstream pathways upon different (nutrient) challenges to identify novel therapeutic targets to curb metabolic diseases},
  language  = {en}
}
@article{SchulzeWehrholdHille2018,
  author    = {Schulze, Sven and Wehrhold, Michel and Hille, Carsten},
  title     = {Femtosecond-Pulsed laser written and etched fiber bragg gratings for fiber-optical biosensing},
  series = {Sensors},
  volume    = {18},
  journal   = {Sensors},
  number    = {9},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s18092844},
  pages     = {20},
  year      = {2018},
  abstract  = {We present the development of a label-free, highly sensitive fiber-optical biosensor for online detection and quantification of biomolecules. Here, the advantages of etched fiber Bragg gratings (eFBG) were used, since they induce a narrowband Bragg wavelength peak in the reflection operation mode. The gratings were fabricated point-by-point via a nonlinear absorption process of a highly focused femtosecond-pulsed laser, without the need of prior coating removal or specific fiber doping. The sensitivity of the Bragg wavelength peak to the surrounding refractive index (SRI), as needed for biochemical sensing, was realized by fiber cladding removal using hydrofluoric acid etching. For evaluation of biosensing capabilities, eFBG fibers were biofunctionalized with a single-stranded DNA aptamer specific for binding the C-reactive protein (CRP). Thus, the CRP-sensitive eFBG fiber-optical biosensor showed a very low limit of detection of 0.82 pg/L, with a dynamic range of CRP detection from approximately 0.8 pg/L to 1.2 mu g/L. The biosensor showed a high specificity to CRP even in the presence of interfering substances. These results suggest that the proposed biosensor is capable for quantification of CRP from trace amounts of clinical samples. In addition, the adaption of this eFBG fiber-optical biosensor for detection of other relevant analytes can be easily realized.},
  language  = {en}
}
@article{BiterovaEsmaeeliMoghaddamTabalvandaniAlanenetal.2018,
  author    = {Biterova, Ekaterina and Esmaeeli Moghaddam Tabalvandani, Mariam and Alanen, Heli I. and Saaranen, Mirva and Ruddock, Lloyd W.},
  title     = {Structures of Angptl3 and Angptl4, modulators of triglyceride levels and coronary artery disease},
  series = {Scientific reports},
  volume    = {8},
  journal   = {Scientific reports},
  publisher = {Nature Publ. Group},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-018-25237-7},
  pages     = {12},
  year      = {2018},
  abstract  = {Coronary artery disease is the most common cause of death globally and is linked to a number of risk factors including serum low density lipoprotein, high density lipoprotein, triglycerides and lipoprotein(a). Recently two proteins, angiopoietin-like protein 3 and 4, have emerged from genetic studies as being factors that significantly modulate plasma triglyceride levels and coronary artery disease. The exact function and mechanism of action of both proteins remains to be elucidated, however, mutations in these proteins results in up to 34\% reduction in coronary artery disease and inhibition of function results in reduced plasma triglyceride levels. Here we report the crystal structures of the fibrinogen-like domains of both proteins. These structures offer new insights into the reported loss of function mutations, the mechanisms of action of the proteins and open up the possibility for the rational design of low molecular weight inhibitors for intervention in coronary artery disease.},
  language  = {en}
}
@article{XiongStollePark2018,
  author    = {Xiong, Chao and Stolle, Claudia and Park, Jaeheung},
  title     = {Climatology of GPS signal loss observed by Swarm satellites},
  series = {Annales geophysicae},
  volume    = {36},
  journal   = {Annales geophysicae},
  number    = {2},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {0992-7689},
  doi       = {10.5194/angeo-36-679-2018},
  pages     = {679 -- 693},
  year      = {2018},
  abstract  = {By using 3-year global positioning system (GPS) measurements from December 2013 to November 2016, we provide in this study a detailed survey on the climatology of the GPS signal loss of Swarm onboard receivers. Our results show that the GPS signal losses prefer to occur at both low latitudes between +/- 5 and +/- 20 degrees magnetic latitude (MLAT) and high latitudes above 60 degrees MLAT in both hemispheres. These events at all latitudes are observed mainly during equinoxes and December solstice months, while totally absent during June solstice months. At low latitudes the GPS signal losses are caused by the equatorial plasma irregularities shortly after sunset, and at high latitude they are also highly related to the large density gradients associated with ionospheric irregularities. Additionally, the high-latitude events are more often observed in the Southern Hemisphere, occurring mainly at the cusp region and along nightside auroral latitudes. The signal losses mainly happen for those GPS rays with elevation angles less than 20 degrees, and more commonly occur when the line of sight between GPS and Swarm satellites is aligned with the shell structure of plasma irregularities. Our results also confirm that the capability of the Swarm receiver has been improved after the bandwidth of the phase-locked loop (PLL) widened, but the updates cannot radically avoid the interruption in tracking GPS satellites caused by the ionospheric plasma irregularities. Additionally, after the PLL bandwidth increased larger than 0.5 Hz, some unexpected signal losses are observed even at middle latitudes, which are not related to the ionospheric plasma irregularities. Our results suggest that rather than 1.0 Hz, a PLL bandwidth of 0.5 Hz is a more suitable value for the Swarm receiver.},
  language  = {en}
}
@article{KucianZuberKohnetal.2018,
  author    = {Kucian, Karin and Zuber, Isabelle and Kohn, Juliane and Poltz, Nadine and Wyschkon, Anne and Esser, G{\"u}nter and von Aster, Michael G.},
  title     = {Relation Between Mathematical Performance, Math Anxiety, and Affective Priming in Children With and Without Developmental Dyscalculia},
  series = {Frontiers in psychology},
  volume    = {9},
  journal   = {Frontiers in psychology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2018.00263},
  pages     = {13},
  year      = {2018},
  abstract  = {Many children show negative emotions related to mathematics and some even develop mathematics anxiety. The present study focused on the relation between negative emotions and arithmetical performance in children with and without developmental dyscalculia (DD) using an affective priming task. Previous findings suggested that arithmetic performance is influenced if an affective prime precedes the presentation of an arithmetic problem. In children with DD specifically, responses to arithmetic operations are supposed to be facilitated by both negative and mathematics-related primes (= negative math priming effect). We investigated mathematical performance, math anxiety, and the domain-general abilities of 172 primary school children (76 with DD and 96 controls). All participants also underwent an affective priming task which consisted of the decision whether a simple arithmetic operation (addition or subtraction) that was preceded by a prime (positive/negative/neutral or mathematics-related) was true or false. Our findings did not reveal a negative math priming effect in children with DD. Furthermore, when considering accuracy levels, gender, or math anxiety, the negative math priming effect could not be replicated. However, children with DD showed more math anxiety when explicitly assessed by a specific math anxiety interview and showed lower mathematical performance compared to controls. Moreover, math anxiety was equally present in boys and girls, even in the earliest stages of schooling, and interfered negatively with performance. In conclusion, mathematics is often associated with negative emotions that can be manifested in specific math anxiety, particularly in children with DD. Importantly, present findings suggest that in the assessed age group, it is more reliable to judge math anxiety and investigate its effects on mathematical performance explicitly by adequate questionnaires than by an affective math priming task.},
  language  = {en}
}
@article{CoesfeldKuesterKuechlyetal.2020,
  author    = {Coesfeld, Jacqueline and Kuester, Theres and Kuechly, Helga U. and Kyba, Christopher C. M.},
  title     = {Reducing variability and removing natural light from nighttime satellite imagery: A case study using the VIIRS DNB},
  series = {Sensors},
  volume    = {20},
  journal   = {Sensors},
  publisher = {MDPI},
  address   = {Basel},
  pages     = {13},
  year      = {2020},
  abstract  = {Temporal variation of natural light sources such as airglow limits the ability of night light sensors to detect changes in small sources of artificial light (such as villages). This study presents a method for correcting for this effect globally, using the satellite radiance detected from regions without artificial light emissions. We developed a routine to define an approximate grid of locations worldwide that do not have regular light emission. We apply this method with a 5 degree equally spaced global grid (total of 2016 individual locations), using data from the Visible Infrared Imaging Radiometer Suite (VIIRS) Day-Night Band (DNB). This code could easily be adapted for other future global sensors. The correction reduces the standard deviation of data in the Earth Observation Group monthly DNB composites by almost a factor of two. The code and datasets presented here are available under an open license by GFZ Data Services, and are implemented in the Radiance Light Trends web application.},
  language  = {en}
}
@article{DunsingLucknerZuehlkeetal.2018,
  author    = {Dunsing, Valentin and Luckner, Madlen and Zuehlke, Boris and Petazzi, Roberto Arturo and Herrmann, Andreas and Chiantia, Salvatore},
  title     = {Optimal fluorescent protein tags for quantifying protein oligomerization in living cells},
  series = {Scientific reports},
  volume    = {8},
  journal   = {Scientific reports},
  publisher = {Nature Publ. Group},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-018-28858-0},
  pages     = {12},
  year      = {2018},
  abstract  = {Fluorescence fluctuation spectroscopy has become a popular toolbox for non-disruptive analysis of molecular interactions in living cells. The quantification of protein oligomerization in the native cellular environment is highly relevant for a detailed understanding of complex biological processes. An important parameter in this context is the molecular brightness, which serves as a direct measure of oligomerization and can be easily extracted from temporal or spatial fluorescence fluctuations. However, fluorescent proteins (FPs) typically used in such studies suffer from complex photophysical transitions and limited maturation, inducing non-fluorescent states. Here, we show how these processes strongly affect molecular brightness measurements. We perform a systematic characterization of non-fluorescent states for commonly used FPs and provide a simple guideline for accurate, unbiased oligomerization measurements in living cells. Further, we focus on novel red FPs and demonstrate that mCherry2, an mCherry variant, possesses superior properties with regards to precise quantification of oligomerization.},
  language  = {en}
}
@article{ZeedenObrehtVeresetal.2020,
  author    = {Zeeden, Christian and Obreht, Igor and Veres, Daniel and Kaboth-Bahr, Stefanie and Hošek, Jan and Marković, Slobodan B. and B{\"o}sken, Janina and Lehmkuhl, Frank and Rolf, Christian and Hambach, Ulrich},
  title     = {Smoothed millennial-scale palaeoclimatic reference data as unconventional comparison targets: Application to European loess records},
  series = {Scientific Reports},
  volume    = {10},
  journal   = {Scientific Reports},
  number    = {1},
  publisher = {Springer Nature},
  address   = {Berlin},
  pages     = {13},
  year      = {2020},
  abstract  = {Millennial-scale palaeoclimate variability has been documented in various terrestrial and marine palaeoclimate proxy records throughout the Northern Hemisphere for the last glacial cycle. Its clear expression and rapid shifts between different states of climate (Greenland Interstadials and Stadials) represents a correlation tool beyond the resolution of e.g. luminescence dating, especially relevant for terrestrial deposits. Usually, comparison of terrestrial proxy datasets and the Greenland ice cores indicates a complex expression of millennial-scale climate variability as recorded in terrestrial geoarchives including loess. Loess is the most widespread terrestrial geoarchive of the Quaternary and especially widespread over Eurasia. However, loess often records a smoothed representation of millennial-scale variability without all fidelity when compared to the Greenland data, this being a relevant limiting feature in integrating loess with other palaeoclimate records. To better understand the loess proxy-response to millennial-scale climate variability, we simulate a proxy signal smoothing by natural processes through application of low-pass filters of delta O-18 data from Greenland, a high-resolution palaeoclimate reference record, alongside speleothem isotope records from the Black Sea-Mediterranean region. We show that low-pass filters represent rather simple models for better constraining the expression of millennial-scale climate variability in low sedimentation environments, and in sediments where proxy-response signals are most likely affected by natural smoothing (by e.g. bioturbation). Interestingly, smoothed datasets from Greenland and the Black Sea-Mediterranean region are most similar in the last similar to 15 ka and between similar to 50-30 ka. Between similar to 30-15 ka, roughly corresponding to the Last Glacial Maximum and the deglaciation, the records show dissimilarities, challenging the construction of robust correlative time-scales in this age range. From our analysis it becomes apparent that patterns of palaeoclimate signals in loess-palaeosol sequences often might be better explained by smoothed Greenland reference data than the original high-resolution Greenland dataset, or other reference data. This opens the possibility to better assess the temporal resolution and palaeoclimate potential of loess-palaeosol sequences in recording supra-regional climate patterns, as well as to securely integrate loess with other chronologically better-resolved palaeoclimate records.},
  language  = {en}
}
@article{RichlyBrauerSchlosser2020,
  author    = {Richly, Keven and Brauer, Janos and Schlosser, Rainer},
  title     = {Predicting location probabilities of drivers to improved dispatch decisions of transportation network companies based on trajectory data},
  series = {Proceedings of the 9th International Conference on Operations Research and Enterprise Systems - ICORES},
  journal   = {Proceedings of the 9th International Conference on Operations Research and Enterprise Systems - ICORES},
  publisher = {Springer},
  address   = {Berlin},
  pages     = {12},
  year      = {2020},
  abstract  = {The demand for peer-to-peer ridesharing services increased over the last years rapidly. To cost-efficiently dispatch orders and communicate accurate pick-up times is challenging as the current location of each available driver is not exactly known since observed locations can be outdated for several seconds. The developed trajectory visualization tool enables transportation network companies to analyze dispatch processes and determine the causes of unexpected delays. As dispatching algorithms are based on the accuracy of arrival time predictions, we account for factors like noise, sample rate, technical and economic limitations as well as the duration of the entire process as they have an impact on the accuracy of spatio-temporal data. To improve dispatching strategies, we propose a prediction approach that provides a probability distribution for a driver's future locations based on patterns observed in past trajectories. We demonstrate the capabilities of our prediction results to ( i) avoid critical delays, (ii) to estimate waiting times with higher confidence, and (iii) to enable risk considerations in dispatching strategies.},
  language  = {en}
}
@article{SoechtingTrapp2020,
  author    = {S{\"o}chting, Maximilian and Trapp, Matthias},
  title     = {Controlling image-stylization techniques using eye tracking},
  series = {Science and Technology Publications},
  journal   = {Science and Technology Publications},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2184-4321},
  pages     = {10},
  year      = {2020},
  abstract  = {With the spread of smart phones capable of taking high-resolution photos and the development of high-speed mobile data infrastructure, digital visual media is becoming one of the most important forms of modern communication. With this development, however, also comes a devaluation of images as a media form with the focus becoming the frequency at which visual content is generated instead of the quality of the content. In this work, an interactive system using image-abstraction techniques and an eye tracking sensor is presented, which allows users to experience diverting and dynamic artworks that react to their eye movement. The underlying modular architecture enables a variety of different interaction techniques that share common design principles, making the interface as intuitive as possible. The resulting experience allows users to experience a game-like interaction in which they aim for a reward, the artwork, while being held under constraints, e.g., not blinking. The co nscious eye movements that are required by some interaction techniques hint an interesting, possible future extension for this work into the field of relaxation exercises and concentration training.},
  language  = {en}
}
@article{CaliendoGoethnerWeissenberger2019,
  author    = {Caliendo, Marco and Goethner, Maximilian and Weißenberger, Martin},
  title     = {Entrepreneurial persistence beyond survival: Measurement and determinants},
  series = {Journal of Small Business Management},
  volume    = {58},
  journal   = {Journal of Small Business Management},
  number    = {3},
  publisher = {Taylor \& Francis},
  address   = {London},
  pages     = {32},
  year      = {2019},
  abstract  = {Entrepreneurial persistence is demonstrated by an entrepreneur's continued positive maintenance of entrepreneurial motivation and constantly renewed active engagement in a new business venture despite counterforces or enticing alternatives. It thus is a crucial factor for entrepreneurs when pursuing and exploiting their business opportunities and in realizing potential economic gains and benefits. Using rich data on a representative sample of German business founders, we investigated the determinants of entrepreneurial persistence. Next to observed survival, we also constructed a hybrid persistence measure capturing the motivational dimension of persistence. We analyzed the influence of individual-level (human capital and personality) and business-related characteristics on both measures as well as their relative importance. We found that the two indicators emphasize different aspects of persistence. For the survival indicator, the predictive power was concentrated in business characteristics and human capital, while for hybrid persistence the dominant factors were business characteristics and personality. Finally, we showed that results were heterogeneous across subgroups. In particular, formerly unemployed founders did not differ in survival chances, but they were more likely to lack a high psychological commitment to their business ventures.},
  language  = {en}
}
@article{NaliboffGlerumBruneetal.2020,
  author    = {Naliboff, John B. and Glerum, Anne and Brune, Sascha and P{\´e}ron-Pinvidic, G. and Wrona, Thilo},
  title     = {Development of 3-D rift heterogeneity through fault network evolution},
  series = {Geophysical Research Letters},
  volume    = {47},
  journal   = {Geophysical Research Letters},
  number    = {13},
  publisher = {John Wiley \& Sons, Inc.},
  address   = {New Jersey},
  pages     = {11},
  year      = {2020},
  abstract  = {Observations of rift and rifted margin architecture suggest that significant spatial and temporal structural heterogeneity develops during the multiphase evolution of continental rifting. Inheritance is often invoked to explain this heterogeneity, such as preexisting anisotropies in rock composition, rheology, and deformation. Here, we use high-resolution 3-D thermal-mechanical numerical models of continental extension to demonstrate that rift-parallel heterogeneity may develop solely through fault network evolution during the transition from distributed to localized deformation. In our models, the initial phase of distributed normal faulting is seeded through randomized initial strength perturbations in an otherwise laterally homogeneous lithosphere extending at a constant rate. Continued extension localizes deformation onto lithosphere-scale faults, which are laterally offset by tens of km and discontinuous along-strike. These results demonstrate that rift- and margin-parallel heterogeneity of large-scale fault patterns may in-part be a natural byproduct of fault network coalescence.},
  language  = {en}
}
@article{ZimmermannDeVeaughGeissToennisetal.2020,
  author    = {Zimmermann, Malte and De Veaugh-Geiss, Joseph P. and T{\"o}nnis, Swantje and Onea, Edgar},
  title     = {(Non-)exhaustivity in focus partitioning across languages},
  series = {Approaches to Hungarian},
  volume    = {16},
  journal   = {Approaches to Hungarian},
  publisher = {John Benjamins},
  address   = {Amsterdam},
  pages     = {24},
  year      = {2020},
  abstract  = {We present novel experimental evidence on the availability and the status of exhaustivity inferences with focus partitioning in German, English, and Hungarian. Results suggest that German and English focus-background clefts and Hungarian focus share important properties, ({\´E}. Kiss 1998, 1999; Szabolcsi 1994; Percus 1997; Onea \& Beaver 2009). Those constructions are anaphoric devices triggering an existence presupposition. EXH-inferences are not obligatory in such constructions in English, German, or Hungarian, against some previous literature (Percus 1997; B{\"u}ring \& Križ 2013; {\´E}. Kiss 1998), but in line with pragmatic analyses of EXH-inferences in clefts (Horn 1981, 2016; Pollard \& Yasavul 2016). The cross-linguistic differences in the distribution of EXH-inferences are attributed to properties of the Hungarian number marking system.},
  language  = {en}
}
@article{ZwickelKahlRychliketal.2018,
  author    = {Zwickel, Theresa and Kahl, Sandra M. and Rychlik, Michael and M{\"u}ller, Marina E. H.},
  title     = {Chemotaxonomy of Mycotoxigenic Small-Spored Alternaria Fungi},
  series = {Frontiers in microbiology},
  volume    = {9},
  journal   = {Frontiers in microbiology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-302X},
  doi       = {10.3389/fmicb.2018.01368},
  pages     = {20},
  year      = {2018},
  abstract  = {Necrotrophic as well as saprophytic small-spored Altemaria (A.) species are annually responsible for major losses of agricultural products, such as cereal crops, associated with the contamination of food and feedstuff with potential health-endangering Altemaria toxins. Knowledge of the metabolic capabilities of different species-groups to form mycotoxins is of importance for a reliable risk assessment. 93 Altemaria strains belonging to the four species groups Alternaria tenuissima, A. arborescens, A. altemata, and A. infectoria were isolated from winter wheat kernels harvested from fields in Germany and Russia and incubated under equal conditions. Chemical analysis by means of an HPLC-MS/MS multi-Alternaria-toxin-method showed that 95\% of all strains were able to form at least one of the targeted 17 non-host specific Altemaria toxins. Simultaneous production of up to 15 (modified) Altemaria toxins by members of the A. tenuissima, A. arborescens, A. altemata species-groups and up to seven toxins by A. infectoria strains was demonstrated. Overall tenuazonic acid was the most extensively formed mycotoxin followed by alternariol and alternariol mono methylether, whereas altertoxin I was the most frequently detected toxin. Sulfoconjugated modifications of alternariol, alternariol mono methylether, altenuisol and altenuene were frequently determined. Unknown perylene quinone derivatives were additionally detected. Strains of the species-group A. infectoria could be segregated from strains of the other three species-groups due to significantly lower toxin levels and the specific production of infectopyrone. Apart from infectopyrone, alterperylenol was also frequently produced by 95\% of the A. infectoria strains. Neither by the concentration nor by the composition of the targeted Altemaria toxins a differentiation between the species-groups A. altemata, A. tenuissima and A. arborescens was possible.},
  language  = {en}
}
@article{HegerNiklesJacobs2018,
  author    = {Heger, Tina and Nikles, Gabriele and Jacobs, Brooke S.},
  title     = {Differentiation in native as well as introduced ranges},
  series = {AoB PLANTS},
  volume    = {10},
  journal   = {AoB PLANTS},
  number    = {1},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {2041-2851},
  doi       = {10.1093/aobpla/ply009},
  pages     = {12},
  year      = {2018},
  abstract  = {Germination, a crucial phase in the life cycle of a plant, can be significantly influenced by competition and facilitation. The aim of this study was to test whether differences in cover of surrounding vegetation can lead to population differentiation in germination behaviour of an annual grassland species, and if so, whether such a differentiation can be found in the native as well as in the introduced range. We used maternal progeny of Erodium cicutarium previously propagated under uniform conditions that had been collected in multiple populations in the native and two introduced ranges, in populations representing extremes in terms of mean and variability of the cover of surrounding vegetation. In the first experiment, we tested the effect of germination temperature and mean cover at the source site on germination, and found interlinked effects of these factors. In seeds from one of the introduced ranges (California), we found indication for a 2-fold dormancy, hindering germination at high temperatures even if physical dormancy was broken and water was available. This behaviour was less strong in high cover populations, indicating cross-generational facilitating effects of dense vegetation. In the second experiment, we tested whether spatial variation in cover of surrounding vegetation has an effect on the proportion of dormant seeds. Contrary to our expectations, we found that across source regions, high variance in cover was associated with higher proportions of seeds germinating directly after storage. In all three regions, germination seemed to match the local environment in terms of climate and vegetation cover. We suggest that this is due to a combined effect of introduction of preadapted genotypes and local evolutionary processes.},
  language  = {en}
}
@article{HesseKlierSgarzietal.2018,
  author    = {Hesse, Julia and Klier, Dennis Tobias and Sgarzi, Massimo and Nsubuga, Anne and Bauer, Christoph and Grenzer, Joerg and H{\"u}bner, Rene and Wislicenus, Marcus and Joshi, Tanmaya and Kumke, Michael Uwe and Stephan, Holger},
  title     = {Rapid Synthesis of Sub-10nm Hexagonal NaYF4-Based Upconverting Nanoparticles using Therminol((R))66},
  series = {ChemistryOpen : including thesis treasury},
  volume    = {7},
  journal   = {ChemistryOpen : including thesis treasury},
  number    = {2},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {2191-1363},
  doi       = {10.1002/open.201700186},
  pages     = {159 -- 168},
  year      = {2018},
  abstract  = {We report a simple one-pot method for the rapid preparation of sub-10nm pure hexagonal (-phase) NaYF4-based upconverting nanoparticles (UCNPs). Using Therminol((R))66 as a co-solvent, monodisperse UCNPs could be obtained in unusually short reaction times. By varying the reaction time and reaction temperature, it was possible to control precisely the particle size and crystalline phase of the UCNPs. The upconversion (UC) luminescence properties of the nanocrystals were tuned by varying the concentrations of the dopants (Nd3+ and Yb3+ sensitizer ions and Er3+ activator ions). The size and phase-purity of the as-synthesized core and core-shell nanocrystals were assessed by using complementary transmission electron microscopy, dynamic light scattering, X-ray diffraction, and small-angle X-ray scattering studies. In-depth photophysical evaluation of the UCNPs was pursued by using steady-state and time-resolved luminescence spectroscopy. An enhancement in the UC intensity was observed if the nanocrystals, doped with optimized concentrations of lanthanide sensitizer/activator ions, were further coated with an inert/active shell. This was attributed to the suppression of surface-related luminescence quenching effects.},
  language  = {en}
}
@article{KaechMatheHubertDennisetal.2018,
  author    = {K{\"a}ch, Heidi and Mathe-Hubert, Hugo and Dennis, Alice B. and Vorburger, Christoph},
  title     = {Rapid evolution of symbiont-mediated resistance compromises biological control of aphids by parasitoids},
  series = {Evolutionary applications},
  volume    = {11},
  journal   = {Evolutionary applications},
  number    = {2},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {1752-4571},
  doi       = {10.1111/eva.12532},
  pages     = {220 -- 230},
  year      = {2018},
  abstract  = {There is growing interest in biological control as a sustainable and environmentally friendly way to control pest insects. Aphids are among the most detrimental agricultural pests worldwide, and parasitoid wasps are frequently employed for their control. The use of asexual parasitoids may improve the effectiveness of biological control because only females kill hosts and because asexual populations have a higher growth rate than sexuals. However, asexuals may have a reduced capacity to track evolutionary change in their host populations. We used a factorial experiment to compare the ability of sexual and asexual populations of the parasitoid Lysiphlebus fabarum to control caged populations of black bean aphids (Aphis fabae) of high and low clonal diversity. The aphids came from a natural population, and one-third of the aphid clones harbored Hamiltonella defensa, a heritable bacterial endosymbiont that increases resistance to parasitoids. We followed aphid and parasitoid population dynamics for 3months but found no evidence that the reproductive mode of parasitoids affected their effectiveness as biocontrol agents, independent of host clonal diversity. Parasitoids failed to control aphids in most cases, because their introduction resulted in strong selection for clones protected by H.defensa. The increasingly resistant aphid populations escaped control by parasitoids, and we even observed parasitoid extinctions in many cages. The rapid evolution of symbiont-conferred resistance in turn imposed selection on parasitoids. In cages where asexual parasitoids persisted until the end of the experiment, they became dominated by a single genotype able to overcome the protection provided by H.defensa. Thus, there was evidence for parasitoid counteradaptation, but it was generally too slow for parasitoids to regain control over aphid populations. It appears that when pest aphids possess defensive symbionts, the presence of parasitoid genotypes able to overcome symbiont-conferred resistance is more important for biocontrol success than their reproductive mode.},
  language  = {en}
}
@article{ShiJoshiTielboergeretal.2018,
  author    = {Shi, Jun and Joshi, Jasmin Radha and Tielboerger, Katja and Verhoeven, Koen J. F. and Macel, Mirka},
  title     = {Costs and benefits of admixture between foreign genotypes and local populations in the field},
  series = {Ecology and evolution},
  volume    = {8},
  journal   = {Ecology and evolution},
  number    = {7},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {2045-7758},
  doi       = {10.1002/ece3.3946},
  pages     = {3675 -- 3684},
  year      = {2018},
  abstract  = {Admixture is the hybridization between populations within one species. It can increase plant fitness and population viability by alleviating inbreeding depression and increasing genetic diversity. However, populations are often adapted to their local environments and admixture with distant populations could break down local adaptation by diluting the locally adapted genomes. Thus, admixed genotypes might be selected against and be outcompeted by locally adapted genotypes in the local environments. To investigate the costs and benefits of admixture, we compared the performance of admixed and within-population F1 and F2 generations of the European plant Lythrum salicaria in a reciprocal transplant experiment at three European field sites over a 2-year period. Despite strong differences between site and plant populations for most of the measured traits, including herbivory, we found limited evidence for local adaptation. The effects of admixture depended on experimental site and plant population, and were positive for some traits. Plant growth and fruit production of some populations increased in admixed offspring and this was strongest with larger parental distances. These effects were only detected in two of our three sites. Our results show that, in the absence of local adaptation, admixture may boost plant performance, and that this is particularly apparent in stressful environments. We suggest that admixture between foreign and local genotypes can potentially be considered in nature conservation to restore populations and/or increase population viability, especially in small inbred or maladapted populations.},
  language  = {en}
}
@misc{FrankKreitz2018,
  author    = {Frank, Mario and Kreitz, Christoph},
  title     = {A theorem prover for scientific and educational purposes},
  series = {Electronic proceedings in theoretical computer science},
  journal   = {Electronic proceedings in theoretical computer science},
  number    = {267},
  publisher = {Open Publishing Association},
  address   = {Sydney},
  issn      = {2075-2180},
  doi       = {10.4204/EPTCS.267.4},
  pages     = {59 -- 69},
  year      = {2018},
  abstract  = {We present a prototype of an integrated reasoning environment for educational purposes. The presented tool is a fragment of a proof assistant and automated theorem prover. We describe the existing and planned functionality of the theorem prover and especially the functionality of the educational fragment. This currently supports working with terms of the untyped lambda calculus and addresses both undergraduate students and researchers. We show how the tool can be used to support the students' understanding of functional programming and discuss general problems related to the process of building theorem proving software that aims at supporting both research and education.},
  language  = {en}
}
@article{TotzEliseevPetrietal.2018,
  author    = {Totz, Sonja Juliana and Eliseev, Alexey V. and Petri, Stefan and Flechsig, Michael and Caesar, Levke and Petoukhov, Vladimir and Coumou, Dim},
  title     = {The dynamical core of the Aeolus 1.0 statistical-dynamical atmosphere model},
  series = {Geoscientific model development : an interactive open access journal of the European Geosciences Union},
  volume    = {11},
  journal   = {Geoscientific model development : an interactive open access journal of the European Geosciences Union},
  number    = {2},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1991-959X},
  doi       = {10.5194/gmd-11-665-2018},
  pages     = {665 -- 679},
  year      = {2018},
  abstract  = {Here, we present novel equations for the large-scale zonal-mean wind as well as those for planetary waves. Together with synoptic parameterization (as presented by Coumou et al., 2011), these form the mathematical description of the dynamical core of Aeolus 1.0. The regions of high azonal wind velocities (planetary waves) are accurately captured for all validation experiments. The zonal-mean zonal wind and the integrated lower troposphere mass flux show good results in particular in the Northern Hemisphere. In the Southern Hemisphere, the model tends to produce too-weak zonal-mean zonal winds and a too-narrow Hadley circulation. We discuss possible reasons for these model biases as well as planned future model improvements and applications.},
  language  = {en}
}
@article{WeithoffTaubeBolius2017,
  author    = {Weithoff, Guntram and Taube, Anne and Bolius, Sarah},
  title     = {The invasion success of the cyanobacterium Cylindrospermopsis raciborskii in experimental mesocosms},
  series = {Aquatic Invasions},
  volume    = {12},
  journal   = {Aquatic Invasions},
  publisher = {Regional Euro-Asian Biological Invasions centre-reabic},
  address   = {Helsinki},
  issn      = {1798-6540},
  doi       = {10.3391/ai.2017.12.3.07},
  pages     = {333 -- 341},
  year      = {2017},
  abstract  = {The potentially toxic, invasive cyanobacterium Cylindrospermopsis raciborskii, originating from sub-tropical regions, has spread into temperate climate zones in almost all continents. Potential factors in its success are temperature, light and nutrient levels. Grazing losses through zooplankton have been measured in the laboratory but are typically not regarded as a factor in (failed) invasion success. In some potentially suitable lakes, C. raciborskii has never been found, although it is present in water bodies close by. Therefore, we tested the invasive potential of three different isolates introduced into natural plankton communities using laboratory mesocosm experiments under three grazing levels: ambient zooplankton densities, removal of large species using 100 mu m mesh and a ca. doubling of large species. Three C. raciborskii isolates originating from the same geographic region (North-East Germany) were added separately to the four replicates of each treatment and kept in semi-continuous cultures for 21 days. Two isolates disappeared from the mesocosms and were also not viable in filtered lake water indicating that the lake water itself or the switch from culture medium to lake water led to the decay of the inoculated C. raciborskii. Only one out of the three isolates persisted in the plankton communities at a rather low level and only in the treatment without larger zooplankton. This result demonstrates that under potentially suitable environmental conditions, top-down control from zooplankton might hamper the establishment of C. raciborskii. Non-metric multidimensional scaling showed distinct variation in resident phytoplankton communities between the different grazing levels, thus differential grazing impact shaped the resident community in different ways allowing C. raciborskii only to invade under competitive (= low grazing pressure) conditions. Furthermore, even after invasion failure, the temporary presence of C. raciborskii influenced the phytoplankton community.},
  language  = {en}
}
@article{VaterMoritzRoepke2018,
  author    = {Vater, Aline and Moritz, Steffen and Roepke, Stefan},
  title     = {Does a narcissism epidemic exist in modern western societies?},
  series = {PLOS ONE},
  volume    = {13},
  journal   = {PLOS ONE},
  number    = {1},
  publisher = {Public Library of Science},
  address   = {San Fransisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0188287},
  pages     = {16},
  year      = {2018},
  abstract  = {Narcissism scores are higher in individualistic cultures compared with more collectivistic cultures. However, the impact of sociocultural factors on narcissism and self-esteem has not been well described. Germany was formerly divided into two different social systems, each with distinct economic, political and national cultures, and was reunified in 1989/90. Between 1949 and 1989/90, West Germany had an individualistic culture, whereas East Germany had a more collectivistic culture. The German reunification provides an exceptional opportunity to investigate the impact of sociocultural and generational differences on narcissism and self-esteem. In this study, we used an anonymous online survey to assess grandiose narcissism with the Narcissistic Personality Inventory (NPI) and the Pathological Narcissism Inventory (PNI) to assess grandiose and vulnerable aspects of narcissism, and self-esteem with the Rosenberg Self-Esteem Scale (RSE) in 1,025 German individuals. Data were analyzed according to age and place of birth. Our results showed that grandiose narcissism was higher and self-esteem was lower in individuals who grew up in former West Germany compared with former East Germany. Further analyses indicated no significant differences in grandiose narcissism, vulnerable narcissism or self-esteem in individuals that entered school after the German reunification (≤ 5 years of age in 1989). In the middle age cohort (6-18 years of age in 1989), significant differences in vulnerable narcissism, grandiose narcissism and self-esteem were observed. In the oldest age cohort (> 19 years of age in 1989), significant differences were only found in one of the two scales assessing grandiose narcissism (NPI). Our data provides empirical evidence that sociocultural factors are associated with differences in narcissism and self-esteem.},
  language  = {en}
}
@article{WolfGillesPeusetal.2018,
  author    = {Wolf, Isabell Ann-Cathrin and Gilles, Maria and Peus, Verena and Scharnholz, Barbara and Seibert, Julia and Jennen-Steinmetz, Christine and Krumm, Bertram and Rietschel, Marcella and Deuschle, Michael and Laucht, Manfred},
  title     = {Impact of prenatal stress on mother-infant dyadic behavior during the still-face paradigm},
  series = {Borderline Personality Disorder and Emotion Dysregulation : the official journal of the National Education Alliance for Borderline Personality Disorder (NEA.BPD) and Dachverband Dialektisch Behaviorale Therapie (DDBT)},
  volume    = {5},
  journal   = {Borderline Personality Disorder and Emotion Dysregulation : the official journal of the National Education Alliance for Borderline Personality Disorder (NEA.BPD) and Dachverband Dialektisch Behaviorale Therapie (DDBT)},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {2051-6673},
  doi       = {10.1186/s40479-018-0078-8},
  pages     = {13},
  year      = {2018},
  abstract  = {Background: Mother-infant interaction provides important training for the infant's ability to cope with stress and the development of resilience. Prenatal stress (PS) and its impact on the offspring's development have long been a focus of stress research, with studies highlighting both harmful and beneficial effects. The aim of the current study was to examine the possible influence of both psychological stress and hypothalamic-pituitary-adrenal (HPA) axis activity during pregnancy with mother-child dyadic behavior following stress exposure. Methods: The behavior of 164 mother-infant dyads during the still-face situation was filmed at six months postpartum and coded into three dyadic patterns: 1) both positive, 2) infant protesting-mother positive, and 3) infant protesting-mother negative. PS exposure was assessed prenatally according to psychological measures (i.e., psychopathological, perceived and psychosocial PS; n = 164) and HPA axis activity measures (maternal salivary cortisol, i.e., cortisol decline and area under the curve with respect to ground (AUCg); n = 134). Results: Mother-infant dyads in both the high- and low-stress groups showed decreasing positive and increasing negative dyadic behavior in the reunion episode, which is associated with the well-known "still-face" and "carry-over" effect. Furthermore, mother-infant dyads with higher psychosocial PS exhibited significantly more positive dyadic behavior than the low psychosocial PS group in the first play episode, but not in the reunion episode. Similarly, mother-infant dyads with high HPA axis activity (i.e. high AUCg) but steeper diurnal cortisol decline (i.e. cortisol decline) displayed significantly less negative behavior in the reunion episode than dyads with low HPA axis activity. No significant results were found for psychopathological stress and perceived stress. Conclusions: The results suggest a beneficial effect of higher psychosocial PS and higher prenatal maternal HPA axis activity in late gestation, which is in line with "stress inoculation" theories.},
  language  = {en}
}
@article{BukowskiSchittkoPetermann2018,
  author    = {Bukowski, Alexandra R. and Schittko, Conrad and Petermann, Jana S.},
  title     = {The strength of negative plant-soil feedback increases from the intraspecific to the interspecific and the functional group level},
  series = {Ecology and evolution},
  volume    = {8},
  journal   = {Ecology and evolution},
  number    = {4},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {2045-7758},
  doi       = {10.1002/ece3.3755},
  pages     = {2280 -- 2289},
  year      = {2018},
  abstract  = {One of the processes that may play a key role in plant species coexistence and ecosystem functioning is plant-soil feedback, the effect of plants on associated soil communities and the resulting feedback on plant performance. Plant-soil feedback at the interspecific level (comparing growth on own soil with growth on soil from different species) has been studied extensively, while plant-soil feedback at the intraspecific level (comparing growth on own soil with growth on soil from different accessions within a species) has only recently gained attention. Very few studies have investigated the direction and strength of feedback among different taxonomic levels, and initial results have been inconclusive, discussing phylogeny, and morphology as possible determinants. To test our hypotheses that the strength of negative feedback on plant performance increases with increasing taxonomic level and that this relationship is explained by morphological similarities, we conducted a greenhouse experiment using species assigned to three taxonomic levels (intraspecific, interspecific, and functional group level). We measured certain fitness-related aboveground traits and used them along literature-derived traits to determine the influence of morphological similarities on the strength and direction of the feedback. We found that the average strength of negative feedback increased from the intraspecific over the interspecific to the functional group level. However, individual accessions and species differed in the direction and strength of the feedback. None of our results could be explained by morphological dissimilarities or individual traits. Synthesis. Our results indicate that negative plant-soil feedback is stronger if the involved plants belong to more distantly related species. We conclude that the taxonomic level is an important factor in the maintenance of plant coexistence with plant-soil feedback as a potential stabilizing mechanism and should be addressed explicitly in coexistence research, while the traits considered here seem to play a minor role.},
  language  = {en}
}
@article{KuecuekgoezeLeimkuehler2018,
  author    = {K{\"u}{\c{c}}{\"u}kg{\"o}ze, G{\"o}khan and Leimk{\"u}hler, Silke},
  title     = {Direct comparison of the four aldehyde oxidase enzymes present in mouse gives insight into their substrate specificities},
  series = {PLOS ONE},
  volume    = {13},
  journal   = {PLOS ONE},
  number    = {1},
  publisher = {Public Library of Science},
  address   = {San Fransisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0191819},
  pages     = {20},
  year      = {2018},
  abstract  = {Mammalian aldehyde oxidases (AOXs) are molybdo-flavoenzymes which are present in many tissues in various mammalian species, including humans and rodents. Different species contain a different number of AOX isoforms. In particular, the reasons why mammals other than humans express a multiplicity of tissue-specific AOX enzymes is unknown. In mouse, the isoforms mAOX1, mAOX3, mAOX4 and mAOX2 are present. We previously established a codon-optimized heterologous expression systems for the mAOX1-4 isoforms in Escherichia coli that gives yield to sufficient amounts of active protein for kinetic characterizations and sets the basis in this study for site-directed mutagenesis and structure-function studies. A direct and simultaneous comparison of the enzymatic properties and characteristics of the four enzymes on a larger number of substrates has never been performed. Here, thirty different structurally related aromatic, aliphatic and N-heterocyclic compounds were used as substrates, and the kinetic parameters of all four mAOX enzymes were directly compared. The results show that especially mAOX4 displays a higher substrate selectivity, while no major differences between mAOX1, mAOX2 and mAOX3 were identified. Generally, mAOX1 was the enzyme with the highest catalytic turnover for most substrates. To understand the factors that contribute to the substrate specificity of mAOX4, site-directed mutagenesis was applied to substitute amino acids in the substrate-binding funnel by the ones present in mAOX1, mAOX3, and mAOX2. An increase in activity was obtained by the amino acid exchange M1088V in the active site identified to be specific for mAOX4, to the amino acid identified in mAOX3.},
  language  = {en}
}
@article{LaraNitzeGrosseetal.2018,
  author    = {Lara, Mark J. and Nitze, Ingmar and Grosse, Guido and Martin, Philip and McGuire, A. David},
  title     = {Reduced arctic tundra productivity linked with landform and climate change interactions},
  series = {Scientific reports},
  volume    = {8},
  journal   = {Scientific reports},
  publisher = {Nature Publ. Group},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-018-20692-8},
  pages     = {10},
  year      = {2018},
  abstract  = {Arctic tundra ecosystems have experienced unprecedented change associated with climate warming over recent decades. Across the Pan-Arctic, vegetation productivity and surface greenness have trended positively over the period of satellite observation. However, since 2011 these trends have slowed considerably, showing signs of browning in many regions. It is unclear what factors are driving this change and which regions/landforms will be most sensitive to future browning. Here we provide evidence linking decadal patterns in arctic greening and browning with regional climate change and local permafrost-driven landscape heterogeneity. We analyzed the spatial variability of decadal-scale trends in surface greenness across the Arctic Coastal Plain of northern Alaska (similar to 60,000 km(2)) using the Landsat archive (1999-2014), in combination with novel 30 m classifications of polygonal tundra and regional watersheds, finding landscape heterogeneity and regional climate change to be the most important factors controlling historical greenness trends. Browning was linked to increased temperature and precipitation, with the exception of young landforms (developed following lake drainage), which will likely continue to green. Spatiotemporal model forecasting suggests carbon uptake potential to be reduced in response to warmer and/or wetter climatic conditions, potentially increasing the net loss of carbon to the atmosphere, at a greater degree than previously expected.},
  language  = {en}
}
@article{DaiMateGlebeetal.2018,
  author    = {Dai, Xiaolin and Mate, Diana M. and Glebe, Ulrich and Garakani, Tayebeh Mirzaei and K{\"o}rner, Andrea and Schwaneberg, Ulrich and B{\"o}ker, Alexander},
  title     = {Sortase-mediated ligation of purely artificial building blocks},
  series = {Polymers},
  volume    = {10},
  journal   = {Polymers},
  number    = {2},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4360},
  doi       = {10.3390/polym10020151},
  pages     = {13},
  year      = {2018},
  abstract  = {Sortase A (SrtA) from Staphylococcus aureus has been often used for ligating a protein with other natural or synthetic compounds in recent years. Here we show that SrtA-mediated ligation (SML) is universally applicable for the linkage of two purely artificial building blocks. Silica nanoparticles (NPs), poly(ethylene glycol) and poly(N-isopropyl acrylamide) are chosen as synthetic building blocks. As a proof of concept, NP-polymer, NP-NP, and polymer-polymer structures are formed by SrtA catalysis. Therefore, the building blocks are equipped with the recognition sequence needed for SrtA reaction-the conserved peptide LPETG-and a pentaglycine motif. The successful formation of the reaction products is shown by means of transmission electron microscopy (TEM), matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-ToF MS), and dynamic light scattering (DLS). The sortase catalyzed linkage of artificial building blocks sets the stage for the development of a new approach to link synthetic structures in cases where their synthesis by established chemical methods is complicated.},
  language  = {en}
}
@article{KrapfMarinariMetzleretal.2018,
  author    = {Krapf, Diego and Marinari, Enzo and Metzler, Ralf and Oshanin, Gleb and Xu, Xinran and Squarcini, Alessio},
  title     = {Power spectral density of a single Brownian trajectory},
  series = {New journal of physics : the open-access journal for physics},
  volume    = {20},
  journal   = {New journal of physics : the open-access journal for physics},
  publisher = {IOP Publ. Ltd.},
  address   = {Bristol},
  issn      = {1367-2630},
  doi       = {10.1088/1367-2630/aaa67c},
  pages     = {30},
  year      = {2018},
  abstract  = {The power spectral density (PSD) of any time-dependent stochastic processX (t) is ameaningful feature of its spectral content. In its text-book definition, the PSD is the Fourier transform of the covariance function of X-t over an infinitely large observation timeT, that is, it is defined as an ensemble-averaged property taken in the limitT -> infinity. Alegitimate question is what information on the PSD can be reliably obtained from single-trajectory experiments, if one goes beyond the standard definition and analyzes the PSD of a single trajectory recorded for a finite observation timeT. In quest for this answer, for a d-dimensional Brownian motion (BM) we calculate the probability density function of a single-trajectory PSD for arbitrary frequency f, finite observation time T and arbitrary number k of projections of the trajectory on different axes. We show analytically that the scaling exponent for the frequency-dependence of the PSD specific to an ensemble of BM trajectories can be already obtained from a single trajectory, while the numerical amplitude in the relation between the ensemble-averaged and single-trajectory PSDs is afluctuating property which varies from realization to realization. The distribution of this amplitude is calculated exactly and is discussed in detail. Our results are confirmed by numerical simulations and single-particle tracking experiments, with remarkably good agreement. In addition we consider a truncated Wiener representation of BM, and the case of a discrete-time lattice random walk. We highlight some differences in the behavior of a single-trajectory PSD for BM and for the two latter situations. The framework developed herein will allow for meaningful physical analysis of experimental stochastic trajectories.},
  language  = {en}
}
@article{GoodwinMuddClubb2018,
  author    = {Goodwin, Guillaume C. H. and Mudd, Simon M. and Clubb, Fiona J.},
  title     = {Unsupervised detection of salt marsh platforms},
  series = {Earth surface dynamics},
  volume    = {6},
  journal   = {Earth surface dynamics},
  number    = {1},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {2196-6311},
  doi       = {10.5194/esurf-6-239-2018},
  pages     = {239 -- 255},
  year      = {2018},
  abstract  = {Salt marshes filter pollutants, protect coastlines against storm surges, and sequester carbon, yet are under threat from sea level rise and anthropogenic modification. The sustained existence of the salt marsh ecosystem depends on the topographic evolution of marsh platforms. Quantifying marsh platform topography is vital for improving the management of these valuable landscapes. The determination of platform boundaries currently relies on supervised classification methods requiring near-infrared data to detect vegetation, or demands labour-intensive field surveys and digitisation. We propose a novel, unsupervised method to reproducibly isolate salt marsh scarps and platforms from a digital elevation model (DEM), referred to as Topographic Identification of Platforms (TIP). Field observations and numerical models show that salt marshes mature into subhorizontal platforms delineated by subvertical scarps. Based on this premise, we identify scarps as lines of local maxima on a slope raster, then fill landmasses from the scarps upward, thus isolating mature marsh platforms. We test the TIP method using lidar-derived DEMs from six salt marshes in England with varying tidal ranges and geometries, for which topographic platforms were manually isolated from tidal flats. Agreement between manual and unsupervised classification exceeds 94\% for DEM resolutions of 1 m, with all but one site maintaining an accuracy superior to 90\% for resolutions up to 3 m. For resolutions of 1 m, platforms detected with the TIP method are comparable in surface area to digitised platforms and have similar elevation distributions. We also find that our method allows for the accurate detection of local block failures as small as 3 times the DEM resolution. Detailed inspection reveals that although tidal creeks were digitised as part of the marsh platform, unsupervised classification categorises them as part of the tidal flat, causing an increase in false negatives and overall platform perimeter. This suggests our method may benefit from combination with existing creek detection algorithms. Fallen blocks and high tidal flat portions, associated with potential pioneer zones, can also lead to differences between our method and supervised mapping. Although pioneer zones prove difficult to classify using a topographic method, we suggest that these transition areas should be considered when analysing erosion and accretion processes, particularly in the case of incipient marsh platforms. Ultimately, we have shown that unsupervised classification of marsh platforms from high-resolution topography is possible and sufficient to monitor and analyse topographic evolution.},
  language  = {en}
}
@misc{BridwellCavanaghCollinsetal.2018,
  author    = {Bridwell, David A. and Cavanagh, James F. and Collins, Anne G. E. and Nunez, Michael D. and Srinivasan, Ramesh and Stober, Sebastian and Calhoun, Vince D.},
  title     = {Moving Beyond ERP Components},
  series = {Frontiers in human neuroscienc},
  volume    = {12},
  journal   = {Frontiers in human neuroscienc},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1662-5161},
  doi       = {10.3389/fnhum.2018.00106},
  pages     = {17},
  year      = {2018},
  abstract  = {Relationships between neuroimaging measures and behavior provide important clues about brain function and cognition in healthy and clinical populations. While electroencephalography (EEG) provides a portable, low cost measure of brain dynamics, it has been somewhat underrepresented in the emerging field of model-based inference. We seek to address this gap in this article by highlighting the utility of linking EEG and behavior, with an emphasis on approaches for EEG analysis that move beyond focusing on peaks or "components" derived from averaging EEG responses across trials and subjects (generating the event-related potential, ERP). First, we review methods for deriving features from EEG in order to enhance the signal within single-trials. These methods include filtering based on user-defined features (i.e., frequency decomposition, time-frequency decomposition), filtering based on data-driven properties (i.e., blind source separation, BSS), and generating more abstract representations of data (e.g., using deep learning). We then review cognitive models which extract latent variables from experimental tasks, including the drift diffusion model (DDM) and reinforcement learning (RL) approaches. Next, we discuss ways to access associations among these measures, including statistical models, data-driven joint models and cognitive joint modeling using hierarchical Bayesian models (HBMs). We think that these methodological tools are likely to contribute to theoretical advancements, and will help inform our understandings of brain dynamics that contribute to moment-to-moment cognitive function.},
  language  = {en}
}
@article{RoderHille2018,
  author    = {Roder, Phillip and Hille, Carsten},
  title     = {Local tissue manipulation via a force- and pressure-controlled AFM micropipette for analysis of cellular processes},
  series = {Scientific reports},
  volume    = {8},
  journal   = {Scientific reports},
  publisher = {Nature Publ. Group},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-018-24255-9},
  pages     = {9},
  year      = {2018},
  abstract  = {Local manipulation of complex tissues at the single-cell level is challenging and requires excellent sealing between the specimen and the micromanipulation device. Here, biological applications for a recently developed loading technique for a force-and pressure-controlled fluidic force microscope micropipette are described. This technique allows for the exact positioning and precise spatiotemporal control of liquid delivery. The feasibility of a local loading technique for tissue applications was investigated using two fluorescent dyes, with which local loading behaviour could be optically visualised. Thus, homogeneous intracellular distribution of CellTracker Red and accumulation of SYTO 9 Green within nuclei was realised in single cells of a tissue preparation. Subsequently, physiological micromanipulation experiments were performed. Salivary gland tissue was pre-incubated with the Ca2+-sensitive dye OGB-1. An intracellular Ca2+ rise was then initiated at the single-cell level by applying dopamine via micropipette. When pre-incubating tissue with the nitric oxide (NO)-sensitive dye DAF-FM, NO release and intercellular NO diffusion was observed after local application of the NO donor SNP. Finally, local micromanipulation of a well-defined area along irregularly shaped cell surfaces of complex biosystems was shown for the first time for the fluidic force microscope micropipette. Thus, this technique is a promising tool for the investigation of the spatiotemporal effects of locally applied substances in complex tissues.},
  language  = {en}
}
@misc{ReichetzederHocher2017,
  author    = {Reichetzeder, Christoph and Hocher, Berthold},
  title     = {DPP4 inhibition prevents AKI},
  series = {Oncotarget},
  volume    = {8},
  journal   = {Oncotarget},
  publisher = {Impact Journals LLC},
  address   = {Orchard Park},
  issn      = {1949-2553},
  doi       = {10.18632/oncotarget.20212},
  pages     = {64655 -- 64656},
  year      = {2017},
  language  = {en}
}
@article{Goychuk2018,
  author    = {Goychuk, Igor},
  title     = {Sensing magnetic fields with magnetosensitive ion channels},
  series = {Sensors},
  volume    = {18},
  journal   = {Sensors},
  number    = {3},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s18030728},
  pages     = {19},
  year      = {2018},
  abstract  = {Magnetic nanoparticles are met across many biological species ranging from magnetosensitive bacteria, fishes, bees, bats, rats, birds, to humans. They can be both of biogenetic origin and due to environmental contamination, being either in paramagnetic or ferromagnetic state. The energy of such naturally occurring single-domain magnetic nanoparticles can reach up to 10-20 room k(B)T in the magnetic field of the Earth, which naturally led to supposition that they can serve as sensory elements in various animals. This work explores within a stochastic modeling framework a fascinating hypothesis of magnetosensitive ion channels with magnetic nanoparticles serving as sensory elements, especially, how realistic it is given a highly dissipative viscoelastic interior of living cells and typical sizes of nanoparticles possibly involved.},
  language  = {en}
}
@misc{Kleuser2018,
  author    = {Kleuser, Burkhard},
  title     = {Divergent role of sphingosine 1-phosphate in liver health and disease},
  series = {International journal of molecular sciences},
  volume    = {19},
  journal   = {International journal of molecular sciences},
  number    = {3},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1422-0067},
  doi       = {10.3390/ijms19030722},
  pages     = {18},
  year      = {2018},
  abstract  = {Two decades ago, sphingosine 1-phosphate (S1P) was discovered as a novel bioactive molecule that regulates a variety of cellular functions. The plethora of S1P-mediated effects is due to the fact that the sphingolipid not only modulates intracellular functions but also acts as a ligand of G protein-coupled receptors after secretion into the extracellular environment. In the plasma, S1P is found in high concentrations, modulating immune cell trafficking and vascular endothelial integrity. The liver is engaged in modulating the plasma S1P content, as it produces apolipoprotein M, which is a chaperone for the S1P transport. Moreover, the liver plays a substantial role in glucose and lipid homeostasis. A dysfunction of glucose and lipid metabolism is connected with the development of liver diseases such as hepatic insulin resistance, non-alcoholic fatty liver disease, or liver fibrosis. Recent studies indicate that S1P is involved in liver pathophysiology and contributes to the development of liver diseases. In this review, the current state of knowledge about S1P and its signaling in the liver is summarized with a specific focus on the dysregulation of S1P signaling in obesity-mediated liver diseases. Thus, the modulation of S1P signaling can be considered as a potential therapeutic target for the treatment of hepatic diseases.},
  language  = {en}
}
@article{KayhanMatthesMarriottHaresignetal.2022,
  author    = {Kayhan, Ezgi and Matthes, Daniel and Marriott Haresign, Ira and B{\´a}nki, Anna and Michel, Christine and Langeloh, Miriam and Wass, Sam and Hoehl, Stefanie},
  title     = {DEEP: A dual EEG pipeline for developmental hyperscanning studies},
  series = {Developmental Cognitive Neuroscience},
  volume    = {54},
  journal   = {Developmental Cognitive Neuroscience},
  publisher = {Elsevier},
  address   = {Amsterdam, Niederlande},
  issn      = {1878-9307},
  doi       = {10.1016/j.dcn.2022.101104},
  pages     = {1 -- 11},
  year      = {2022},
  abstract  = {Cutting-edge hyperscanning methods led to a paradigm shift in social neuroscience. It allowed researchers to measure dynamic mutual alignment of neural processes between two or more individuals in naturalistic contexts. The ever-growing interest in hyperscanning research calls for the development of transparent and validated data analysis methods to further advance the field. We have developed and tested a dual electroencephalography (EEG) analysis pipeline, namely DEEP. Following the preprocessing of the data, DEEP allows users to calculate Phase Locking Values (PLVs) and cross-frequency PLVs as indices of inter-brain phase alignment of dyads as well as time-frequency responses and EEG power for each participant. The pipeline also includes scripts to control for spurious correlations. Our goal is to contribute to open and reproducible science practices by making DEEP publicly available together with an example mother-infant EEG hyperscanning dataset.},
  language  = {en}
}
@article{CostaTomazdeSouzaAyzelHeistermann2020,
  author    = {Costa Tomaz de Souza, Arthur and Ayzel, Georgy and Heistermann, Maik},
  title     = {Quantifying the location error of precipitation nowcasts},
  series = {Advances in meteorology},
  volume    = {2020},
  journal   = {Advances in meteorology},
  publisher = {Hindawi},
  address   = {London},
  issn      = {1687-9309},
  doi       = {10.1155/2020/8841913},
  pages     = {12},
  year      = {2020},
  abstract  = {In precipitation nowcasting, it is common to track the motion of precipitation in a sequence of weather radar images and to extrapolate this motion into the future. The total error of such a prediction consists of an error in the predicted location of a precipitation feature and an error in the change of precipitation intensity over lead time. So far, verification measures did not allow isolating the extent of location errors, making it difficult to specifically improve nowcast models with regard to location prediction. In this paper, we introduce a framework to directly quantify the location error. To that end, we detect and track scale-invariant precipitation features (corners) in radar images. We then consider these observed tracks as the true reference in order to evaluate the performance (or, inversely, the error) of any model that aims to predict the future location of a precipitation feature. Hence, the location error of a forecast at any lead time Delta t ahead of the forecast time t corresponds to the Euclidean distance between the observed and the predicted feature locations at t + Delta t. Based on this framework, we carried out a benchmarking case study using one year worth of weather radar composites of the German Weather Service. We evaluated the performance of four extrapolation models, two of which are based on the linear extrapolation of corner motion from t - 1 to t (LK-Lin1) and t - 4 to t (LK-Lin4) and the other two are based on the Dense Inverse Search (DIS) method: motion vectors obtained from DIS are used to predict feature locations by linear (DIS-Lin1) and Semi-Lagrangian extrapolation (DIS-Rot1). Of those four models, DIS-Lin1 and LK-Lin4 turned out to be the most skillful with regard to the prediction of feature location, while we also found that the model skill dramatically depends on the sinuosity of the observed tracks. The dataset of 376,125 detected feature tracks in 2016 is openly available to foster the improvement of location prediction in extrapolation-based nowcasting models.},
  language  = {en}
}
@article{GrubicWierzba2021,
  author    = {Grubic, Mira and Wierzba, Marta},
  title     = {The German additive particle noch},
  series = {Glossa : a journal of general linguistics},
  volume    = {6},
  journal   = {Glossa : a journal of general linguistics},
  number    = {1},
  publisher = {Ubiquity Press},
  address   = {London},
  issn      = {2397-1835},
  doi       = {10.5334/gjgl.1275},
  pages     = {29},
  year      = {2021},
  abstract  = {The particle noch ('still') can have an additive reading similar to auch ('also'). We argue that both particles indicate that a previously partially answered QUD is re-opened to add a further answer. The particles differ in that the QUD, in the case of auch, can be re-opened with respect to the same topic situation, whereas noch indicates that the QUD is re-opened with respect to a new topic situation. This account predicts a difference in the accommodation behavior of the two particles. We present an experiment whose results are in line with this prediction.},
  language  = {en}
}
@article{MalassTarkhanov2020,
  author    = {Malass, Ihsane and Tarkhanov, Nikolaj Nikolaevič},
  title     = {A perturbation of the de Rham complex},
  series = {Journal of Siberian Federal University : Mathematics \& Physics},
  volume    = {13},
  journal   = {Journal of Siberian Federal University : Mathematics \& Physics},
  number    = {5},
  publisher = {Siberian Federal University},
  address   = {Krasnojarsk},
  issn      = {1997-1397},
  doi       = {10.17516/1997-1397-2020-13-5-519-532},
  pages     = {519 -- 532},
  year      = {2020},
  abstract  = {We consider a perturbation of the de Rham complex on a compact manifold with boundary. This perturbation goes beyond the framework of complexes, and so cohomology does not apply to it. On the other hand, its curvature is "small", hence there is a natural way to introduce an Euler characteristic and develop a Lefschetz theory for the perturbation. This work is intended as an attempt to develop a cohomology theory for arbitrary sequences of linear mappings.},
  language  = {en}
}
@article{TiedemannIobbiNivolLeimkuehler2022,
  author    = {Tiedemann, Kim and Iobbi-Nivol, Chantal and Leimk{\"u}hler, Silke},
  title     = {The Role of the Nucleotides in the Insertion of the bis-Molybdopterin Guanine Dinucleotide Cofactor into apo-Molybdoenzymes},
  series = {Molecules},
  volume    = {27},
  journal   = {Molecules},
  edition   = {9},
  publisher = {MDPI},
  address   = {Basel, Schweiz},
  issn      = {1420-3049},
  doi       = {10.3390/molecules27092993},
  pages     = {1 -- 15},
  year      = {2022},
  abstract  = {The role of the GMP nucleotides of the bis-molybdopterin guanine dinucleotide (bis-MGD) cofactor of the DMSO reductase family has long been a subject of discussion. The recent characterization of the bis-molybdopterin (bis-Mo-MPT) cofactor present in the E. coli YdhV protein, which differs from bis-MGD solely by the absence of the nucleotides, now enables studying the role of the nucleotides of bis-MGD and bis-MPT cofactors in Moco insertion and the activity of molybdoenzymes in direct comparison. Using the well-known E. coli TMAO reductase TorA as a model enzyme for cofactor insertion, we were able to show that the GMP nucleotides of bis-MGD are crucial for the insertion of the bis-MGD cofactor into apo-TorA.},
  language  = {en}
}
@article{OuerguiDelleliBouassidaetal.2021,
  author    = {Ouergui, Ibrahim and Delleli, Slaheddine and Bouassida, Anissa and Bouhlel, Ezdine and Chaabene, Helmi and Ardig{\`o}, Luca Paolo and Franchini, Emerson},
  title     = {Technical-tactical analysis of small combat games in male kickboxers},
  series = {BMC Sports Science, Medicine and Rehabilitation},
  journal   = {BMC Sports Science, Medicine and Rehabilitation},
  number    = {13},
  publisher = {Springer Nature},
  address   = {Berlin},
  issn      = {2052-1847},
  doi       = {10.1186/s13102-021-00391-0},
  pages     = {8},
  year      = {2021},
  abstract  = {Background: To handle the competition demands, sparring drills are used for specific technical-tactical training as well as physical-physiological conditioning in combat sports. While the effects of different area sizes and number of within-round sparring partners on physiological and perceptive responses in combats sports were examined in previous studies, technical and tactical aspects were not investigated. This study investigated the effect of different within-round sparring partners number (i.e., at a time; 1 vs. 1, 1 vs. 2, and 1 vs. 4) and area sizes (2 m × 2 m, 4 m × 4 m, and 6 m × 6 m) variation on the technical-tactical aspects of small combat games in kickboxing. Method: Twenty male kickboxers (mean ± standard deviation, age: 20.3 ± 0.9 years), regularly competing in regional and national events randomly performed nine different kickboxing combats, lasting 2 min each. All combats were video recorded and analyzed using the software Dartfish. Results: Results showed that the total number of punches was significantly higher in 1 versus 4 compared with 1 versus 1 (p = 0.011, d = 0.83). Further, the total number of kicks was significantly higher in 1 versus 4 compared with 1 versus 1 and 1 versus 2 (p < 0.001; d = 0.99 and d = 0.83, respectively). Moreover, the total number of kick combinations was significantly higher in 1 versus 4 compared with 1 versus 1 and 1 versus 2 (p < 0.001; d = 1.05 and d = 0.95, respectively). The same outcome was significantly lower in 2 m × 2 m compared with 4 m × 4 m and 6 m × 6 m areas (p = 0.010 and d = - 0.45; p < 0.001 and d = - 0.6, respectively). The number of block-and-parry was significantly higher in 1 versus 4 compared with 1 versus 1 (p < 0.001, d = 1.45) and 1 versus 2 (p = 0.046, d = 0.61) and in 2 m × 2 m compared with 4 m × 4 m and 6 × 6 m areas (p < 0.001; d = 0.47 and d = 0.66, respectively). Backwards lean actions occurred more often in 2 m × 2 m compared with 4 m × 4 m (p = 0.009, d = 0.53) and 6 m × 6 m (p = 0.003, d = 0.60). However, the number of foot defenses was significantly lower in 2 m × 2 m compared with 6 m × 6 m (p < 0.001, d = 1.04) and 4 m × 4 m (p = 0.004, d = 0.63). Additionally, the number of clinches was significantly higher in 1 versus 1 compared with 1 versus 2 (p = 0.002, d = 0.7) and 1 versus 4 (p = 0.034, d = 0.45). Conclusions: This study provides practical insights into how to manipulate within-round sparring partners' number and/or area size to train specific kickboxing technical-tactical fundamentals.},
  language  = {en}
}
@misc{YarmanScheller2020,
  author    = {Yarman, Aysu and Scheller, Frieder W.},
  title     = {How reliable is the electrochemical readout of MIP sensors?},
  series = {Sensors},
  volume    = {20},
  journal   = {Sensors},
  number    = {9},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s20092677},
  pages     = {23},
  year      = {2020},
  abstract  = {Electrochemical methods offer the simple characterization of the synthesis of molecularly imprinted polymers (MIPs) and the readouts of target binding. The binding of electroinactive analytes can be detected indirectly by their modulating effect on the diffusional permeability of a redox marker through thin MIP films. However, this process generates an overall signal, which may include nonspecific interactions with the nonimprinted surface and adsorption at the electrode surface in addition to (specific) binding to the cavities. Redox-active low-molecular-weight targets and metalloproteins enable a more specific direct quantification of their binding to MIPs by measuring the faradaic current. The in situ characterization of enzymes, MIP-based mimics of redox enzymes or enzyme-labeled targets, is based on the indication of an electroactive product. This approach allows the determination of both the activity of the bio(mimetic) catalyst and of the substrate concentration.},
  language  = {en}
}
@article{AbdallaAdamAharonianetal.2020,
  author    = {Abdalla, Hassan E. and Adam, Remi and Aharonian, Felix A. and Benkhali, Faical Ait and Ang{\"u}ner, Ekrem Oǧuzhan and Arakawa, Masanori and Arcaro, C and Armand, Catherine and Armstrong, T. and Egberts, Kathrin},
  title     = {Very high energy γ-ray emission from two blazars of unknown redshift and upper limits on their distance},
  series = {Monthly Notices of the Royal Astronomical Society},
  volume    = {494},
  journal   = {Monthly Notices of the Royal Astronomical Society},
  number    = {4},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  pages     = {13},
  year      = {2020},
  abstract  = {We report on the detection of very high energy (VHE; E > 100 GeV) gamma-ray emission from the BL Lac objects KUV 00311-1938 and PKS 1440-389 with the High Energy Stereoscopic System (H.E.S.S.). H.E.S.S. observations were accompanied or preceded by multiwavelength observations with Fermi/LAT, XRT and UVOT onboard the Swift satellite, and ATOM. Based on an extrapolation of the Fermi/LAT spectrum towards the VHE gamma-ray regime, we deduce a 95 per cent confidence level upper limit on the unknown redshift of KUV 00311-1938 of z < 0.98 and of PKS 1440-389 of z < 0.53. When combined with previous spectroscopy results, the redshift of KUV 00311-1938 is constrained to 0.51 <= z < 0.98 and of PKS 1440-389 to 0.14 (sic) z < 0.53.},
  language  = {en}
}
@article{WeithoffBell2022,
  author    = {Weithoff, Guntram and Bell, Elanor Margaret},
  title     = {Complex Trophic Interactions in an Acidophilic Microbial Community},
  series = {Microorganisms},
  volume    = {10},
  journal   = {Microorganisms},
  edition   = {7},
  publisher = {MDPI},
  address   = {Basel, Schweiz},
  issn      = {2076-2607},
  doi       = {10.3390/microorganisms10071340},
  pages     = {1 -- 10},
  year      = {2022},
  abstract  = {Extreme habitats often harbor specific communities that differ substantially from non-extreme habitats. In many cases, these communities are characterized by archaea, bacteria and protists, whereas the number of species of metazoa and higher plants is relatively low. In extremely acidic habitats, mostly prokaryotes and protists thrive, and only very few metazoa thrive, for example, rotifers. Since many studies have investigated the physiology and ecology of individual species, there is still a gap in research on direct, trophic interactions among extremophiles. To fill this gap, we experimentally studied the trophic interactions between a predatory protist (Actinophrys sol, Heliozoa) and its prey, the rotifers Elosa woralli and Cephalodella sp., the ciliate Urosomoida sp. and the mixotrophic protist Chlamydomonas acidophila (a green phytoflagellate, Chlorophyta). We found substantial predation pressure on all animal prey. High densities of Chlamydomonas acidophila reduced the predation impact on the rotifers by interfering with the feeding behaviour of A. sol. These trophic relations represent a natural case of intraguild predation, with Chlamydomonas acidophila being the common prey and the rotifers/ciliate and A. sol being the intraguild prey and predator, respectively. We further studied this intraguild predation along a resource gradient using Cephalodella sp. as the intraguild prey. The interactions among the three species led to an increase in relative rotifer abundance with increasing resource (Chlamydomonas) densities. By applying a series of laboratory experiments, we revealed the complexity of trophic interactions within a natural extremophilic community.},
  language  = {en}
}
@article{PrasseIversenLienhardetal.2022,
  author    = {Prasse, Paul and Iversen, Pascal and Lienhard, Matthias and Thedinga, Kristina and Herwig, Ralf and Scheffer, Tobias},
  title     = {Pre-Training on In Vitro and Fine-Tuning on Patient-Derived Data Improves Deep Neural Networks for Anti-Cancer Drug-Sensitivity Prediction},
  series = {MDPI},
  volume    = {14},
  journal   = {MDPI},
  edition   = {16},
  publisher = {MDPI},
  address   = {Basel, Schweiz},
  issn      = {2072-6694},
  doi       = {10.3390/cancers14163950},
  pages     = {1 -- 14},
  year      = {2022},
  abstract  = {Large-scale databases that report the inhibitory capacities of many combinations of candidate drug compounds and cultivated cancer cell lines have driven the development of preclinical drug-sensitivity models based on machine learning. However, cultivated cell lines have devolved from human cancer cells over years or even decades under selective pressure in culture conditions. Moreover, models that have been trained on in vitro data cannot account for interactions with other types of cells. Drug-response data that are based on patient-derived cell cultures, xenografts, and organoids, on the other hand, are not available in the quantities that are needed to train high-capacity machine-learning models. We found that pre-training deep neural network models of drug sensitivity on in vitro drug-sensitivity databases before fine-tuning the model parameters on patient-derived data improves the models' accuracy and improves the biological plausibility of the features, compared to training only on patient-derived data. From our experiments, we can conclude that pre-trained models outperform models that have been trained on the target domains in the vast majority of cases.},
  language  = {en}
}
@article{RajuKoetz2021,
  author    = {Raju, Rajarshi Roy and Koetz, Joachim},
  title     = {Inner rotation of Pickering Janus emulsions},
  series = {Nanomaterials : open access journal},
  volume    = {11},
  journal   = {Nanomaterials : open access journal},
  number    = {12},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2079-4991},
  doi       = {10.3390/nano11123312},
  pages     = {6},
  year      = {2021},
  abstract  = {Janus droplets were prepared by vortex mixing of three non-mixable liquids, i.e., olive oil, silicone oil and water, in the presence of gold nanoparticles (AuNPs) in the aqueous phase and magnetite nanoparticles (MNPs) in the olive oil. The resulting Pickering emulsions were stabilized by a red-colored AuNP layer at the olive oil/water interface and MNPs at the oil/oil interface. The core-shell droplets can be stimulated by an external magnetic field. Surprisingly, an inner rotation of the silicon droplet is observed when MNPs are fixed at the inner silicon droplet interface. This is the first example of a controlled movement of the inner parts of complex double emulsions by magnetic manipulation via interfacially confined magnetic nanoparticles.},
  language  = {en}
}
@article{FuchsGrosseStraussetal.2018,
  author    = {Fuchs, Matthias and Grosse, Guido and Strauss, Jens and G{\"u}nther, Frank and Grigoriev, Mikhail N. and Maximov, Georgy M. and Hugelius, Gustaf},
  title     = {Carbon and nitrogen pools in thermokarst-affected permafrost landscapes in Arctic Siberia},
  series = {Biogeosciences},
  volume    = {15},
  journal   = {Biogeosciences},
  number    = {3},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1726-4170},
  doi       = {10.5194/bg-15-953-2018},
  pages     = {953 -- 971},
  year      = {2018},
  abstract  = {Ice-rich yedoma-dominated landscapes store considerable amounts of organic carbon (C) and nitrogen (N) and are vulnerable to degradation under climate warming. We investigate the C and N pools in two thermokarst-affected yedoma landscapes - on Sobo-Sise Island and on Bykovsky Peninsula in the north of eastern Siberia. Soil cores up to 3m depth were collected along geomorphic gradients and analysed for organic C and N contents. A high vertical sampling density in the profiles allowed the calculation of C and N stocks for short soil column intervals and enhanced understanding of within-core parameter variability. Profile-level C and N stocks were scaled to the landscape level based on landform classifications from 5 m resolution, multispectral RapidEye satellite imagery. Mean landscape C and N storage in the first metre of soil for Sobo-Sise Island is estimated to be 20.2 kg C m(-2) and 1.8 kg N m(-2) and for Bykovsky Peninsula 25.9 kg C m(-2) and 2.2 kg N m(-2). Radiocarbon dating demonstrates the Holocene age of thermokarst basin deposits but also suggests the presence of thick Holoceneage cover layers which can reach up to 2 m on top of intact yedoma landforms. Reconstructed sedimentation rates of 0.10-0.57 mm yr(-1) suggest sustained mineral soil accumulation across all investigated landforms. Both yedoma and thermokarst landforms are characterized by limited accumulation of organic soil layers (peat). We further estimate that an active layer deepening of about 100 cm will increase organic C availability in a seasonally thawed state in the two study areas by similar to 5.8 Tg (13.2 kg C m(-2)). Our study demonstrates the importance of increasing the number of C and N storage inventories in ice-rich yedoma and thermokarst environments in order to account for high variability of permafrost and thermokarst environments in pan-permafrost soil C and N pool estimates.},
  language  = {en}
}
@article{SauermannHoehle2018,
  author    = {Sauermann, Antje and H{\"o}hle, Barbara},
  title     = {Word order in German child language and child-directed speech},
  series = {Glossa: A Journal of General Linguistics},
  volume    = {3},
  journal   = {Glossa: A Journal of General Linguistics},
  number    = {1},
  publisher = {Ubiquity Press LTD},
  address   = {London},
  issn      = {2397-1835},
  doi       = {10.5334/gjgl.281},
  pages     = {32},
  year      = {2018},
  abstract  = {We report two corpus analyses to examine the impact of animacy, definiteness, givenness and type of referring expression on the ordering of double objects in the spontaneous speech of German-speaking two- to four-year-old children and the child-directed speech of their mothers. The first corpus analysis revealed that definiteness, givenness and type of referring expression influenced word order variation in child language and child-directed speech when the type of referring expression distinguished between pronouns and lexical noun phrases. These results correspond to previous child language studies in English (e.g., de Marneffe et al. 2012). Extending the scope of previous studies, our second corpus analysis examined the role of different pronoun types on word order. It revealed that word order in child language and child-directed speech was predictable from the types of pronouns used. Different types of pronouns were associated with different sentence positions but also showed a strong correlation to givenness and definiteness. Yet, the distinction between pronoun types diminished the effects of givenness so that givenness had an independent impact on word order only in child-directed speech but not in child language. Our results support a multi-factorial approach to word order in German. Moreover, they underline the strong impact of the type of referring expression on word order and suggest that it plays a crucial role in the acquisition of the factors influencing word order variation.},
  language  = {en}
}
@article{BadalyanDierichStibaetal.2014,
  author    = {Badalyan, Artavazd and Dierich, Marlen and Stiba, Konstanze and Schwuchow, Viola and Leimk{\"u}hler, Silke and Wollenberger, Ulla},
  title     = {Electrical wiring of the aldehyde oxidoreductase PaoABC with a polymer containing osmium redox centers},
  series = {Biosensors},
  volume    = {4},
  journal   = {Biosensors},
  number    = {4},
  publisher = {MDPI},
  address   = {Basel},
  doi       = {10.3390/bios4040403},
  pages     = {403 -- 421},
  year      = {2014},
  abstract  = {Biosensors for the detection of benzaldehyde and g-aminobutyric acid (GABA) are reported using aldehyde oxidoreductase PaoABC from Escherichia coli immobilized in a polymer containing bound low potential osmium redox complexes. The electrically connected enzyme already electrooxidizes benzaldehyde at potentials below -0.15 V (vs. Ag|AgCl, 1 M KCl). The pH-dependence of benzaldehyde oxidation can be strongly influenced by the ionic strength. The effect is similar with the soluble osmium redox complex and therefore indicates a clear electrostatic effect on the bioelectrocatalytic efficiency of PaoABC in the osmium containing redox polymer. At lower ionic strength, the pH-optimum is high and can be switched to low pH-values at high ionic strength. This offers biosensing at high and low pH-values. A "reagentless" biosensor has been formed with enzyme wired onto a screen-printed electrode in a flow cell device. The response time to addition of benzaldehyde is 30 s, and the measuring range is between 10-150 µM and the detection limit of 5 µM (signal to noise ratio 3:1) of benzaldehyde. The relative standard deviation in a series (n = 13) for 200 µM benzaldehyde is 1.9\%. For the biosensor, a response to succinic semialdehyde was also identified. Based on this response and the ability to work at high pH a biosensor for GABA is proposed by coimmobilizing GABA-aminotransferase (GABA-T) and PaoABC in the osmium containing redox polymer.},
  language  = {en}
}
@article{OguntundeAbiodunLischeidetal.2020,
  author    = {Oguntunde, Philip G. and Abiodun, Babatunde Joseph and Lischeid, Gunnar and Abatan, Abayomi A.},
  title     = {Droughts projection over the Niger and Volta River basins of West Africa at specific global warming levels},
  series = {International Journal of Climatology},
  volume    = {40},
  journal   = {International Journal of Climatology},
  number    = {13},
  publisher = {John Wiley \& Sons, Inc.},
  address   = {New Jersey},
  pages     = {12},
  year      = {2020},
  abstract  = {This study investigates possible impacts of four global warming levels (GWLs: GWL1.5, GWL2.0, GWL2.5, and GWL3.0) on drought characteristics over Niger River basin (NRB) and Volta River basin (VRB). Two drought indices-Standardized Precipitation Index (SPI) and Standardized Precipitation-Evapotranspiration Index (SPEI)-were employed in characterizing droughts in 20 multi-model simulation outputs from the Coordinated Regional Climate Downscaling Experiment (CORDEX). The performance of the simulation in reproducing basic hydro-climatological features and severe drought characteristics (i.e., magnitude and frequency) in the basins were evaluated. The projected changes in the future drought frequency were quantified and compared under the four GWLs for two climate forcing scenarios (RCP8.5 and RCP4.5). The regional climate model (RCM) ensemble gives a realistic simulation of historical hydro-climatological variables needed to calculate the drought indices. With SPEI, the simulation ensemble projects an increase in the magnitude and frequency of severe droughts over both basins (NRB and VRB) at all GWLs, but the increase, which grows with the GWLs, is higher over NRB than over VRB. More than 75\% of the simulations agree on the projected increase at GWL1.5 and all simulations agree on the increase at higher GWLs. With SPI, the projected changes in severe drought is weaker and the magnitude remains the same at all GWLs, suggesting that SPI projection may underestimate impacts of the GWLs on the intensity and severity of future drought. The results of this study have application in mitigating impact of global warming on future drought risk over the regional water systems.},
  language  = {en}
}
@article{OmaneHoehle2020,
  author    = {Omane, Paul Okyere and H{\"o}hle, Barbara},
  title     = {Acquiring syntactic variability},
  series = {Frontiers in communication},
  volume    = {2021},
  journal   = {Frontiers in communication},
  publisher = {Frontiers Media},
  address   = {Lausanne, Schweiz},
  issn      = {2297-900X},
  doi       = {10.3389/fcomm.2021.604951},
  pages     = {15},
  year      = {2020},
  abstract  = {This paper investigates the predictions of the Derivational Complexity Hypothesis by studying the acquisition of wh-questions in 4- and 5-year-old Akan-speaking children in an experimental approach using an elicited production and an elicited imitation task. Akan has two types of wh-question structures (wh-in-situ and wh-ex-situ questions), which allows an investigation of children's acquisition of these two question structures and their preferences for one or the other. Our results show that adults prefer to use wh-ex-situ questions over wh-in-situ questions. The results from the children show that both age groups have the two question structures in their linguistic repertoire. However, they differ in their preferences in usage in the elicited production task: while the 5-year-olds preferred the wh-in-situ structure over the wh-ex-situ structure, the 4-year-olds showed a selective preference for the wh-in-situ structure in who-questions. These findings suggest a developmental change in wh-question preferences in Akan-learning children between 4 and 5 years of age with a so far unobserved u-shaped developmental pattern. In the elicited imitation task, all groups showed a strong tendency to maintain the structure of in-situ and ex-situ questions in repeating grammatical questions. When repairing ungrammatical ex-situ questions, structural changes to grammatical in-situ questions were hardly observed but the insertion of missing morphemes while keeping the ex-situ structure. Together, our findings provide only partial support for the Derivational Complexity Hypothesis.},
  language  = {en}
}
@article{Reich2020,
  author    = {Reich, Eli},
  title     = {The return of liberal rabbinic education to Berlin},
  series = {Nordisk judaistik = Scandinavian Jewish studies},
  volume    = {31},
  journal   = {Nordisk judaistik = Scandinavian Jewish studies},
  number    = {1},
  publisher = {Donner Institute},
  address   = {{\AA}bo},
  issn      = {0348-1646},
  doi       = {10.30752/nj.84891},
  pages     = {87 -- 92},
  year      = {2020},
  abstract  = {In Berlin two rabbinical seminaries, a Reform and a Conservative, have recently been established. The historical and intellectual roots of these institutions in the nineteenth century is sketched, and then contrasted with the present curriculum and the religious profile of the students. Some theological questions for the future of these projects conclude the article.},
  language  = {en}
}
@article{Baumgardt2021,
  author    = {Baumgardt, Iris},
  title     = {Berufliche Orientierung von Kindern im Grundschulalter},
  publisher = {Schneider Verlag Hohengehren GmbH},
  address   = {Baltmannsweiler},
  isbn      = {978-3-8340-2199-1},
  doi       = {10.3278/9783763971886},
  pages     = {VII, 197},
  year      = {2021},
  abstract  = {Die berufliche Orientierung von Kindern im Grundschulalter ist bislang nur in Ans{\"a}tzen erforscht. Gleichwohl gibt es berufsorientierende Angebote, die auf verschiedenen Ebenen Grundschulkinder adressieren. Die Untersuchung fokussiert aktuelle Forschungsergebnisse, ausgew{\"a}hlte Initiativen, Kinderb{\"u}cher, Unterrichtsmaterialien usw. zur beruflichen Orientierung von Kindern. Mit dem Ziel der Entwicklung und Ausdifferenzierung eines facettenreichen beruflichen Selbstkonzeptes von Kindern werden spezifische Forschungs- und Entwicklungspotenziale aufgezeigt.},
  language  = {de}
}
@article{TaffarelloSrinivasanSamprognaMohoretal.2018,
  author    = {Taffarello, Denise and Srinivasan, Raghavan and Samprogna Mohor, Guilherme and Bittencourt Guimaraes, Joao Luis and Calijuri, Maria do Carmo and Mendiondo, Eduardo Mario},
  title     = {Modeling freshwater quality scenarios with ecosystem-based adaptation in the headwaters of the Cantareira system, Brazil},
  series = {Hydrology and earth system sciences : HESS},
  volume    = {22},
  journal   = {Hydrology and earth system sciences : HESS},
  number    = {9},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1027-5606},
  doi       = {10.5194/hess-22-4699-2018},
  pages     = {4699 -- 4723},
  year      = {2018},
  abstract  = {Although hydrologic models provide hypothesis testing of complex dynamics occurring at catchments, fresh-water quality modeling is still incipient at many subtropical headwaters. In Brazil, a few modeling studies assess freshwater nutrients, limiting policies on hydrologic ecosystem services. This paper aims to compare freshwater quality scenarios under different land-use and land-cover (LULC) change, one of them related to ecosystem-based adaptation (EbA), in Brazilian headwaters. Using the spatially semi-distributed Soil and Water Assessment Tool (SWAT) model, nitrate, total phosphorous (TP) and sediment were modeled in catchments ranging from 7.2 to 1037 km(2). These head-waters were eligible areas of the Brazilian payment for ecosystem services (PES) projects in the Cantareira water supply system, which had supplied water to 9 million people in the Sao Paulo metropolitan region (SPMR). We considered SWAT modeling of three LULC scenarios: (i) recent past scenario (S1), with historical LULC in 1990; (ii) current land-use scenario (S2), with LULC for the period 2010-2015 with field validation; and (iii) future land-use scenario with PES (S2 + EbA). This latter scenario proposed forest cover restoration through EbA following the river basin plan by 2035. These three LULC scenarios were tested with a selected record of rainfall and evapotranspiration observed in 2006-2014, with the occurrence of extreme droughts. To assess hydrologic services, we proposed the hydrologic service index (HSI), as a new composite metric comparing water pollution levels (WPL) for reference catchments, related to the grey water footprint (greyWF) and water yield. On the one hand, water quality simulations allowed for the regionalization of greyWF at spatial scales under LULC scenarios. According to the critical threshold, HSI identified areas as less or more sustainable catchments. On the other hand, conservation practices simulated through the S2 + EbA scenario envisaged not only additional and viable best management practices (BMP), but also preventive decision-making at the headwaters of water supply systems.},
  language  = {en}
}
@article{MiticGrafeBatsiosetal.2022,
  author    = {Mitic, Kristina and Grafe, Marianne and Batsios, Petros and Meyer, Irene},
  title     = {Partial Disassembly of the Nuclear Pore Complex Proteins during Semi-Closed Mitosis in Dictyostelium discoideum},
  series = {Cells},
  volume    = {11},
  journal   = {Cells},
  number    = {3},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4409},
  doi       = {10.3390/cells11030407},
  pages     = {14},
  year      = {2022},
  abstract  = {Dictyostelium cells undergo a semi-closed mitosis, during which the nuclear envelope (NE) persists; however, free diffusion between the cytoplasm and the nucleus takes place. To permit the formation of the mitotic spindle, the nuclear envelope must be permeabilized in order to allow diffusion of tubulin dimers and spindle assembly factors into the nucleus. In Aspergillus, free diffusion of proteins between the cytoplasm and the nucleus is achieved by a partial disassembly of the nuclear pore complexes (NPCs) prior to spindle assembly. In order to determine whether this is also the case in Dictyostelium, we analysed components of the NPC by immunofluorescence microscopy and live cell imaging and studied their behaviour during interphase and mitosis. We observed that the NPCs are absent from the contact area of the nucleoli and that some nucleoporins also localize to the centrosome and the spindle poles. In addition, we could show that, during mitosis, the central FG protein NUP62, two inner ring components and Gle1 depart from the NPCs, while all other tested NUPs remained at the NE. This leads to the conclusion that indeed a partial disassembly of the NPCs takes place, which contributes to permeabilisation of the NE during semi-closed mitosis.},
  language  = {en}
}
@article{MattisBeckmannReinetal.2022,
  author    = {Mattis, Toni and Beckmann, Tom and Rein, Patrick and Hirschfeld, Robert},
  title     = {First-class concepts},
  series = {Journal of object technology : JOT / ETH Z{\"u}rich, Department of Computer Science},
  volume    = {21},
  journal   = {Journal of object technology : JOT / ETH Z{\"u}rich, Department of Computer Science},
  number    = {2},
  publisher = {ETH Z{\"u}rich, Department of Computer Science},
  address   = {Z{\"u}rich},
  issn      = {1660-1769},
  doi       = {10.5381/jot.2022.21.2.a6},
  pages     = {1 -- 15},
  year      = {2022},
  abstract  = {Ideally, programs are partitioned into independently maintainable and understandable modules. As a system grows, its architecture gradually loses the capability to accommodate new concepts in a modular way. While refactoring is expensive and not always possible, and the programming language might lack dedicated primary language constructs to express certain cross-cutting concerns, programmers are still able to explain and delineate convoluted concepts through secondary means: code comments, use of whitespace and arrangement of code, documentation, or communicating tacit knowledge. <br /> Secondary constructs are easy to change and provide high flexibility in communicating cross-cutting concerns and other concepts among programmers. However, such secondary constructs usually have no reified representation that can be explored and manipulated as first-class entities through the programming environment. <br /> In this exploratory work, we discuss novel ways to express a wide range of concepts, including cross-cutting concerns, patterns, and lifecycle artifacts independently of the dominant decomposition imposed by an existing architecture. We propose the representation of concepts as first-class objects inside the programming environment that retain the capability to change as easily as code comments. We explore new tools that allow programmers to view, navigate, and change programs based on conceptual perspectives. In a small case study, we demonstrate how such views can be created and how the programming experience changes from draining programmers' attention by stretching it across multiple modules toward focusing it on cohesively presented concepts. Our designs are geared toward facilitating multiple secondary perspectives on a system to co-exist in symbiosis with the original architecture, hence making it easier to explore, understand, and explain complex contexts and narratives that are hard or impossible to express using primary modularity constructs.},
  language  = {en}
}
@article{MarciszJasseyKosakyanetal.2020,
  author    = {Marcisz, Katarzyna and Jassey, Vincent E. J. and Kosakyan, Anush and Krashevska, Valentyna and Lahr, Daniel J. G. and Lara, Enrique and Lamentowicz, Lukasz and Lamentowicz, Mariusz and Macumber, Andrew and Mazei, Yuri and Mitchell, Edward A. D. and Nasser, Nawaf A. and Patterson, R. Timothy and Roe, Helen M. and Singer, David and Tsyganov, Andrey N. and Fournier, Bertrand},
  title     = {Testate amoeba functional traits and their use in paleoecology},
  series = {Frontiers in Ecology and Evolution},
  volume    = {8},
  journal   = {Frontiers in Ecology and Evolution},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-701X},
  doi       = {10.3389/fevo.2020.575966},
  pages     = {28},
  year      = {2020},
  abstract  = {This review provides a synthesis of current knowledge on the morphological and functional traits of testate amoebae, a polyphyletic group of protists commonly used as proxies of past hydrological changes in paleoecological investigations from peatland, lake sediment and soil archives. A trait-based approach to understanding testate amoebae ecology and paleoecology has gained in popularity in recent years, with research showing that morphological characteristics provide complementary information to the commonly used environmental inferences based on testate amoeba (morpho-)species data. We provide a broad overview of testate amoeba morphological and functional traits and trait-environment relationships in the context of ecology, evolution, genetics, biogeography, and paleoecology. As examples we report upon previous ecological and paleoecological studies that used trait-based approaches, and describe key testate amoebae traits that can be used to improve the interpretation of environmental studies. We also highlight knowledge gaps and speculate on potential future directions for the application of trait-based approaches in testate amoeba research.},
  language  = {en}
}
@article{GrafeHofmannBatsiosetal.2020,
  author    = {Grafe, Marianne and Hofmann, Phillip and Batsios, Petros and Meyer, Irene and Gr{\"a}f, Ralph},
  title     = {In vivo assembly of a Dictyostelium lamin mutant induced by light, mechanical stress, and pH},
  series = {Cells : open access journal},
  volume    = {9},
  journal   = {Cells : open access journal},
  number    = {8},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4409},
  doi       = {10.3390/cells9081834},
  pages     = {14},
  year      = {2020},
  abstract  = {We expressedDictyosteliumlamin (NE81) lacking both a functional nuclear localization signal and a CAAX-box for C-terminal lipid modification. This lamin mutant assembled into supramolecular, three-dimensional clusters in the cytosol that disassembled at the onset of mitosis and re-assembled in late telophase, thus mimicking the behavior of the endogenous protein. As disassembly is regulated by CDK1-mediated phosphorylation at serine 122, we generated a phosphomimetic S122E mutant called GFP-NE81-S122E-Delta NLS Delta CLIM. Surprisingly, during imaging, the fusion protein assembled into cytosolic clusters, similar to the protein lacking the phosphomimetic mutation. Clusters disassembled again in the darkness. Assembly could be induced with blue but not green or near ultraviolet light, and it was independent of the fusion tag. Assembly similarly occurred upon cell flattening. Earlier reports and own observations suggested that both blue light and cell flattening could result in a decrease of intracellular pH. Indeed, keeping the cells at low pH also reversibly induced cluster formation. Our results indicate that lamin assembly can be induced by various stress factors and that these are transduced via intracellular acidification. Although these effects have been shown in a phosphomimetic CDK1 mutant of theDictyosteliumlamin, they are likely relevant also for wild-type lamin.},
  language  = {en}
}
@article{NeumannWollenberger2020,
  author    = {Neumann, Bettina and Wollenberger, Ulla},
  title     = {Electrochemical biosensors employing natural and artificial heme peroxidases on semiconductors},
  series = {Sensors},
  volume    = {20},
  journal   = {Sensors},
  number    = {13},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s20133692},
  pages     = {24},
  year      = {2020},
  abstract  = {Heme peroxidases are widely used as biological recognition elements in electrochemical biosensors for hydrogen peroxide and phenolic compounds. Various nature-derived and fully synthetic heme peroxidase mimics have been designed and their potential for replacing the natural enzymes in biosensors has been investigated. The use of semiconducting materials as transducers can thereby offer new opportunities with respect to catalyst immobilization, reaction stimulation, or read-out. This review focuses on approaches for the construction of electrochemical biosensors employing natural heme peroxidases as well as various mimics immobilized on semiconducting electrode surfaces. It will outline important advances made so far as well as the novel applications resulting thereof.},
  language  = {en}
}
@misc{GarciaBonillas2021,
  author    = {Garc{\´i}a Bonillas, Rodrigo},
  title     = {Viva Babel : Long live Babel},
  series = {Alea : estudos neolatinos},
  volume    = {23},
  journal   = {Alea : estudos neolatinos},
  number    = {2},
  publisher = {Universidade Federal do Rio de Janeiro, Faculdade de Letras},
  address   = {Rio de Janeiro RJ},
  issn      = {1517-106X},
  doi       = {10.1590/1517-106X/2021232344350},
  pages     = {344 -- 350},
  year      = {2021},
  language  = {pt}
}
@article{RoseGroegerHoelzle2021,
  author    = {Rose, Robert and Groeger, Lars and H{\"o}lzle, Katharina},
  title     = {The Emergence of Shared Leadership in Innovation Labs},
  series = {Frontiers in Psychology},
  volume    = {12},
  journal   = {Frontiers in Psychology},
  publisher = {Frontiers in psychology},
  address   = {Lausanne, Schweiz},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2021.685167},
  pages     = {1 -- 13},
  year      = {2021},
  abstract  = {Implementing innovation laboratories to leverage intrapreneurship are an increasingly popular organizational practice. A typical feature in these creative environments are semi-autonomous teams in which multiple members collectively exert leadership influence, thereby challenging traditional command-and-control conceptions of leadership. An extensive body of research on the team-centric concept of shared leadership has recognized the potential for pluralized leadership structures in enhancing team effectiveness; however, little empirical work has been conducted in organizational contexts in which creativity is key. This study set out to explore antecedents of shared leadership and its influence on team creativity in an innovation lab. Building on extant shared leadership and innovation research, we propose antecedents customary to creative teamwork, that is, experimental culture, task reflexivity, and voice. Multisource data were collected from 104 team members and 49 evaluations of 29 coaches nested in 21 teams working in a prototypical innovation lab. We identify factors specific to creative teamwork that facilitate the emergence of shared leadership by providing room for experimentation, encouraging team members to speak up in the creative process, and cultivating a reflective application of entrepreneurial thinking. We provide specific exemplary activities for innovation lab teams to increase levels of shared leadership.},
  language  = {en}
}