@article{Werner2017,
  author    = {Werner, Petra},
  title     = {Franz Julius Ferdinand Meyen: gef{\"o}rdert und fr{\"u}hvollendet},
  series = {HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies},
  volume    = {XVIII},
  journal   = {HiN : Alexander von Humboldt im Netz ; International Review for Humboldtian Studies},
  number    = {34},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  issn      = {1617-5239},
  doi       = {10.18443/247},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-395819},
  pages     = {147 -- 164},
  year      = {2017},
  abstract  = {Franz Ferdinand Julius Meyen (1804-1840) ver{\"o}ffentlichte auf sehr vielen Gebieten der Biologie wichtige Arbeiten, vor allem in Botanik und Zoologie. Mit Unterst{\"u}tzung Alexander von Humboldts gelang es ihm, auf dem Forschungsschiff „Prinzess Louise" anzuheuern und als Schiffsarzt an einer mehrj{\"a}hrigen Weltreise teilzunehmen. Humboldt, der einige Regionen ebenfalls besucht und erforscht hatte, unterst{\"u}tzte seinen jungen Kollegen bei der Vorbereitung seiner Reise. Meyen ver{\"o}ffentlichte seine Reiseergebnisse bereits kurz nach seiner R{\"u}ckkehr, gef{\"o}rdert von Christian Gottfried Nees von Esenbeck (1776-1858), sowohl als zweiteiligen historischen Reisebericht als auch in sieben Einzelabhandlungen. Einige Ergebnisse, die er, schwerkrank, nicht selbst verwerten konnte, {\"u}bergab er noch bei Lebzeiten zur Bearbeitung an Spezialisten, andere wurden posthum von Mitgliedern der Leopoldina publiziert. Meyen brachte u. a. eine umfangreiche Sammlung an Vogelpr{\"a}paraten mit, zu denen auch das Erstbeschreibungsexemplar des von ihm so genannten Spheniscus humboldti (Trivialname: Humboldt-Pinguin) geh{\"o}rt.},
  language  = {de}
}
@misc{Wesselmann2020,
  author    = {Wesselmann, Katharina},
  title     = {Review of Rachel Bryant Davies: Victorian Epic Burlesques. A Critical Anthology of Nineteenth-Century Theatrical Entertainments after Homer},
  series = {PaRDeS : Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien = Transformative Translations in Jewish History and Culture},
  volume    = {2020},
  journal   = {PaRDeS : Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien = Transformative Translations in Jewish History and Culture},
  number    = {11},
  editor    = {Amb{\"u}hl, Annemarie},
  issn      = {2364-7612},
  doi       = {10.34679/thersites.vol11.181},
  pages     = {379 -- 384},
  year      = {2020},
  language  = {en}
}
@article{West2020,
  author    = {West, Thomas},
  title     = {Grand Theft Auto V},
  series = {„Wir alle treffen Entscheidungen im Leben, aber letztendlich treffen unsere Entscheidungen uns." : didaktische Potenziale digitaler Spielwelten},
  journal   = {„Wir alle treffen Entscheidungen im Leben, aber letztendlich treffen unsere Entscheidungen uns." : didaktische Potenziale digitaler Spielwelten},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-489-0},
  doi       = {10.25932/publishup-48572},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-485723},
  pages     = {195 -- 217},
  year      = {2020},
  language  = {de}
}
@article{WestphalKalinowskiHoferichteretal.2022,
  author    = {Westphal, Andrea and Kalinowski, Eva and Hoferichter, Clara Josepha and Vock, Miriam},
  title     = {K-12 teachers' stress and burnout during the COVID-19 pandemic: A systematic review},
  series = {Frontiers in Psychology},
  journal   = {Frontiers in Psychology},
  publisher = {Frontiers},
  address   = {Lausanne, Schweiz},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2022.920326},
  pages     = {1 -- 29},
  year      = {2022},
  abstract  = {We present the first systematic literature review on stress and burnout in K-12 teachers during the COVID-19 pandemic. Based on a systematic literature search, we identified 17 studies that included 9,874 K-12 teachers from around the world. These studies showed some indication that burnout did increase during the COVID-19 pandemic. There were, however, almost no differences in the levels of stress and burnout experienced by K-12 teachers compared to individuals employed in other occupational fields. School principals' leadership styles emerged as an organizational characteristic that is highly relevant for K-12 teachers' levels of stress and burnout. Individual teacher characteristics associated with burnout were K-12 teachers' personality, self-efficacy in online teaching, and perceived vulnerability to COVID-19. In order to reduce stress, there was an indication that stress-management training in combination with training in technology use for teaching may be superior to stress-management training alone. Future research needs to adopt more longitudinal designs and examine the interplay between individual and organizational characteristics in the development of teacher stress and burnout during the COVID-19 pandemic and beyond.},
  language  = {en}
}
@article{WestphalKalinowskiHoferichteretal.2022,
  author    = {Westphal, Andrea and Kalinowski, Eva and Hoferichter, Clara Josepha and Vock, Miriam},
  title     = {K-12 teachers' stress and burnout during the COVID-19 pandemic},
  series = {Frontiers in psychology},
  volume    = {13},
  journal   = {Frontiers in psychology},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2022.920326},
  pages     = {29},
  year      = {2022},
  abstract  = {We present the first systematic literature review on stress and burnout in K-12 teachers during the COVID-19 pandemic. Based on a systematic literature search, we identified 17 studies that included 9,874 K-12 teachers from around the world. These studies showed some indication that burnout did increase during the COVID-19 pandemic. There were, however, almost no differences in the levels of stress and burnout experienced by K-12 teachers compared to individuals employed in other occupational fields. School principals' leadership styles emerged as an organizational characteristic that is highly relevant for K-12 teachers' levels of stress and burnout. Individual teacher characteristics associated with burnout were K-12 teachers' personality, self-efficacy in online teaching, and perceived vulnerability to COVID-19. In order to reduce stress, there was an indication that stress-management training in combination with training in technology use for teaching may be superior to stress-management training alone. Future research needs to adopt more longitudinal designs and examine the interplay between individual and organizational characteristics in the development of teacher stress and burnout during the COVID-19 pandemic and beyond.},
  language  = {en}
}
@article{WestphalVockKretschmann2021,
  author    = {Westphal, Andrea and Vock, Miriam and Kretschmann, Julia},
  title     = {Unravelling the relationship between teacher-assigned grades, student personality, and standardized test scores},
  series = {Frontiers in psychology / Frontiers Research Foundation},
  journal   = {Frontiers in psychology / Frontiers Research Foundation},
  number    = {12},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2021.627440},
  pages     = {11},
  year      = {2021},
  abstract  = {The Big Five personality traits play a major role in student achievement. As such, there is consistent evidence that students that are more conscientious receive better teacher-assigned grades in secondary school. However, research often does not support the claim that students that are more conscientious similarly achieve higher scores in domain-specific standardized achievement tests. Based on the Invest-and-Accrue Model, we argue that conscientiousness explains to some extent why certain students receive better grades despite similar academic accomplishments (i.e., achieving similar scores in domain-specific standardized achievement tests). Therefore, the present study examines to what extent the relationship between student personality and teacher-assigned grades consists of direct as opposed to indirect associations (via subject-specific standardized test scores). We used a representative sample of 14,710 ninth-grade students to estimate these direct and indirect pathways in mathematics and German. Structural equation models showed that test scores explained between 8 and 11\% of the variance in teacher-assigned grades in mathematics and German. The Big Five personality traits in students additionally explained between 8 and 10\% of the variance in grades. Finally, the personality-grade relationship consisted of direct (0.02 | β| ≤ 0.27) and indirect associations via test scores (0.01 | β| ≤ 0.07). Conscientiousness explained discrepancies between teacher-assigned grades and students' scores in domain-specific standardized tests to a greater extent than any of the other Big Five personality traits. Our findings suggest that students that are more conscientious may invest more effort to accomplish classroom goals, but fall short of mastery.},
  language  = {en}
}
@article{WetzelScholtkaSchumacheretal.2021,
  author    = {Wetzel, Alexandra Nicole and Scholtka, Bettina and Schumacher, Fabian and Rawel, Harshadrai Manilal and Geisend{\"o}rfer, Birte and Kleuser, Burkhard},
  title     = {Epigenetic DNA methylation of EBI3 modulates human interleukin-35 formation via NFkB signaling},
  series = {International journal of molecular sciences},
  volume    = {22},
  journal   = {International journal of molecular sciences},
  number    = {10},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1422-0067},
  doi       = {10.3390/ijms22105329},
  pages     = {21},
  year      = {2021},
  abstract  = {Ulcerative colitis (UC), a severe chronic disease with unclear etiology that is associated with increased risk for colorectal cancer, is accompanied by dysregulation of cytokines. Epstein-Barr virus-induced gene 3 (EBI3) encodes a subunit in the unique heterodimeric IL-12 cytokine family of either pro- or anti-inflammatory function. After having recently demonstrated that upregulation of EBI3 by histone acetylation alleviates disease symptoms in a dextran sulfate sodium (DSS)-treated mouse model of chronic colitis, we now aimed to examine a possible further epigenetic regulation of EBI3 by DNA methylation under inflammatory conditions. Treatment with the DNA methyltransferase inhibitor (DNMTi) decitabine (DAC) and TNF alpha led to synergistic upregulation of EBI3 in human colon epithelial cells (HCEC). Use of different signaling pathway inhibitors indicated NF kappa B signaling was necessary and proportional to the synergistic EBI3 induction. MALDI-TOF/MS and HPLC-ESIMS/MS analysis of DAC/TNF alpha-treated HCEC identified IL-12p35 as the most probable binding partner to form a functional protein. EBI3/IL-12p35 heterodimers (IL-35) induce their own gene upregulation, something that was indeed observed in HCEC cultured with media from previously DAC/TNF alpha-treated HCEC. These results suggest that under inflammatory and demethylating conditions the upregulation of EBI3 results in the formation of anti-inflammatory IL-35, which might be considered as a therapeutic target in colitis.},
  language  = {en}
}
@article{WetzelKochPreiseretal.2022,
  author    = {Wetzel, Anna-Jasmin and Koch, Roland and Preiser, Christine and M{\"u}ller, Regina and Klemmt, Malte and Ranisch, Robert and Ehni, Hans-J{\"o}rg and Wiesing, Urban and Rieger, Monika A. and Henking, Tanja and Joos, Stefanie},
  title     = {Ethical, legal, and social implications of symptom checker Apps in primary Health Care (CHECK.APP)},
  series = {JMIR Research Protocols},
  volume    = {11},
  journal   = {JMIR Research Protocols},
  number    = {5},
  publisher = {JMIR Research Protocols},
  address   = {Toronto},
  issn      = {1929-0748},
  doi       = {10.2196/34026},
  pages     = {11},
  year      = {2022},
  abstract  = {Background: Symptom checker apps (SCAs) are accessible tools that provide early symptom assessment for users. The ethical, legal, and social implications of SCAs and their impact on the patient-physician relationship, the health care providers, and the health care system have sparsely been examined. This study protocol describes an approach to investigate the possible impacts and implications of SCAs on different levels of health care provision. It considers the perspectives of the users, nonusers, general practitioners (GPs), and health care experts. Objective: We aim to assess a comprehensive overview of the use of SCAs and address problematic issues, if any. The primary outcomes of this study are empirically informed multi-perspective recommendations for different stakeholders on the ethical, legal, and social implications of SCAs. Methods: Quantitative and qualitative methods will be used in several overlapping and interconnected study phases. In study phase 1, a comprehensive literature review will be conducted to assess the ethical, legal, social, and systemic impacts of SCAs. Study phase 2 comprises a survey that will be analyzed with a logistic regression. It aims to assess the user degree of SCAs in Germany as well as the predictors for SCA usage. Study phase 3 will investigate self-observational diaries and user interviews, which will be analyzed as integrated cases to assess user perspectives, usage pattern, and arising problems. Study phase 4 will comprise GP interviews to assess their experiences, perspectives, self-image, and concepts and will be analyzed with the basic procedure by Kruse. Moreover, interviews with health care experts will be conducted in study phase 3 and will be analyzed by using the reflexive thematical analysis approach of Braun and Clark. Results: Study phase 1 will be completed in November 2021. We expect the results of study phase 2 in December 2021 and February 2022. In study phase 3, interviews are currently being conducted. The final study endpoint will be in February 2023. Conclusions: The possible ethical, legal, social, and systemic impacts of a widespread use of SCAs that affect stakeholders and stakeholder groups on different levels of health care will be identified. The proposed methodological approach provides a multifaceted and diverse empirical basis for a broad discussion on these implications.},
  language  = {en}
}
@incollection{WetzelReedSchenck2023,
  author    = {Wetzel, Johanna M. and Reed, Kate and Schenck, Marcia C.},
  title     = {"Writing with my professors"},
  series = {Writing Together: Kollaboratives Schreiben mit Personen aus dem Feld},
  volume    = {45},
  booktitle = {Writing Together: Kollaboratives Schreiben mit Personen aus dem Feld},
  publisher = {Transcript Verlag},
  address   = {Bielefeld},
  isbn      = {978-3-8394-6399-4},
  doi       = {10.14361/9783839463994-002},
  pages     = {31 -- 53},
  year      = {2023},
  abstract  = {Kollaboratives Forschen quer zu hegemonialen Wissensordnungen gilt als wichtiger Baustein dekolonialer Wissenspraxis. Gemeinsame Schreibprozesse von Wissenschaftler*innen und ihren nicht-wissenschaftlichen Forschungspartner*innen sind allerdings selten und eine methodologische und forschungspraktische Reflexion fehlt. Die Beitr{\"a}ger*innen widmen sich diesen L{\"u}cken, indem sie erfolgreiche, aber auch gescheiterte Projekte kollaborativer Textproduktion zwischen Universit{\"a}t und Feld vorstellen und auf ihr Potenzial als transformative und dekoloniale Wissenspraxis befragen. So entsteht eine praktische Orientierungshilfe, die gleichzeitig die interdisziplin{\"a}re Diskussion anregt.},
  language  = {en}
}
@phdthesis{Wetzel2021,
  author    = {Wetzel, Maria},
  title     = {Pore space alterations and their impact on hydraulic and mechanical rock properties quantified by numerical simulations},
  doi       = {10.25932/publishup-51206},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-512064},
  school      = {Universit{\"a}t Potsdam},
  pages     = {XI, 107},
  year      = {2021},
  abstract  = {Geochemical processes such as mineral dissolution and precipitation alter the microstructure of rocks, and thereby affect their hydraulic and mechanical behaviour. Quantifying these property changes and considering them in reservoir simulations is essential for a sustainable utilisation of the geological subsurface. Due to the lack of alternatives, analytical methods and empirical relations are currently applied to estimate evolving hydraulic and mechanical rock properties associated with chemical reactions. However, the predictive capabilities of analytical approaches remain limited, since they assume idealised microstructures, and thus are not able to reflect property evolution for dynamic processes. Hence, aim of the present thesis is to improve the prediction of permeability and stiffness changes resulting from pore space alterations of reservoir sandstones. A detailed representation of rock microstructure, including the morphology and connectivity of pores, is essential to accurately determine physical rock properties. For that purpose, three-dimensional pore-scale models of typical reservoir sandstones, obtained from highly resolved micro-computed tomography (micro-CT), are used to numerically calculate permeability and stiffness. In order to adequately depict characteristic distributions of secondary minerals, the virtual samples are systematically altered and resulting trends among the geometric, hydraulic, and mechanical rock properties are quantified. It is demonstrated that the geochemical reaction regime controls the location of mineral precipitation within the pore space, and thereby crucially affects the permeability evolution. This emphasises the requirement of determining distinctive porosity-permeability relationships by means of digital pore-scale models. By contrast, a substantial impact of spatial alterations patterns on the stiffness evolution of reservoir sandstones are only observed in case of certain microstructures, such as highly porous granular rocks or sandstones comprising framework-supporting cementations. In order to construct synthetic granular samples a process-based approach is proposed including grain deposition and diagenetic cementation. It is demonstrated that the generated samples reliably represent the microstructural complexity of natural sandstones. Thereby, general limitations of imaging techniques can be overcome and various realisations of granular rocks can be flexibly produced. These can be further altered by virtual experiments, offering a fast and cost-effective way to examine the impact of precipitation, dissolution or fracturing on various petrophysical correlations. The presented research work provides methodological principles to quantify trends in permeability and stiffness resulting from geochemical processes. The calculated physical property relations are directly linked to pore-scale alterations, and thus have a higher accuracy than commonly applied analytical approaches. This will considerably improve the predictive capabilities of reservoir models, and is further relevant to assess and reduce potential risks, such as productivity or injectivity losses as well as reservoir compaction or fault reactivation. Hence, the proposed method is of paramount importance for a wide range of natural and engineered subsurface applications, including geothermal energy systems, hydrocarbon reservoirs, CO2 and energy storage as well as hydrothermal deposit exploration.},
  language  = {en}
}
@article{WetzelKempkaKuehn2020,
  author    = {Wetzel, Maria and Kempka, Thomas and K{\"u}hn, Michael},
  title     = {Hydraulic and mechanical impacts of pore space alterations within a sandstone quantified by a flow velocity-dependent precipitation approach},
  series = {Materials},
  volume    = {13},
  journal   = {Materials},
  number    = {14},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1996-1944},
  doi       = {10.3390/ma13143100},
  pages     = {20},
  year      = {2020},
  abstract  = {Geochemical processes change the microstructure of rocks and thereby affect their physical behaviour at the macro scale. A micro-computer tomography (micro-CT) scan of a typical reservoir sandstone is used to numerically examine the impact of three spatial alteration patterns on pore morphology, permeability and elastic moduli by correlating precipitation with the local flow velocity magnitude. The results demonstrate that the location of mineral growth strongly affects the permeability decrease with variations by up to four orders in magnitude. Precipitation in regions of high flow velocities is characterised by a predominant clogging of pore throats and a drastic permeability reduction, which can be roughly described by the power law relation with an exponent of 20. A continuous alteration of the pore structure by uniform mineral growth reduces the permeability comparable to the power law with an exponent of four or the Kozeny-Carman relation. Preferential precipitation in regions of low flow velocities predominantly affects smaller throats and pores with a minor impact on the flow regime, where the permeability decrease is considerably below that calculated by the power law with an exponent of two. Despite their complete distinctive impact on hydraulics, the spatial precipitation patterns only slightly affect the increase in elastic rock properties with differences by up to 6.3\% between the investigated scenarios. Hence, an adequate characterisation of the spatial precipitation pattern is crucial to quantify changes in hydraulic rock properties, whereas the present study shows that its impact on elastic rock parameters is limited. The calculated relations between porosity and permeability, as well as elastic moduli can be applied for upscaling micro-scale findings to reservoir-scale models to improve their predictive capabilities, what is of paramount importance for a sustainable utilisation of the geological subsurface.},
  language  = {en}
}
@article{WetzelKempkaKuehn2018,
  author    = {Wetzel, Maria and Kempka, Thomas and K{\"u}hn, Michael},
  title     = {Quantifying rock weakening due to decreasing calcite mineral content by numerical simulations},
  series = {Materials},
  volume    = {11},
  journal   = {Materials},
  number    = {4},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1996-1944},
  doi       = {10.3390/ma11040542},
  pages     = {19},
  year      = {2018},
  abstract  = {The quantification of changes in geomechanical properties due to chemical reactions is of paramount importance for geological subsurface utilisation, since mineral dissolution generally reduces rock stiffness. In the present study, the effective elastic moduli of two digital rock samples, the Fontainebleau and Bentheim sandstones, are numerically determined based on micro-CT images. Reduction in rock stiffness due to the dissolution of 10\% calcite cement by volume out of the pore network is quantified for three synthetic spatial calcite distributions (coating, partial filling and random) using representative sub-cubes derived from the digital rock samples. Due to the reduced calcite content, bulk and shear moduli decrease by 34\% and 38\% in maximum, respectively. Total porosity is clearly the dominant parameter, while spatial calcite distribution has a minor impact, except for a randomly chosen cement distribution within the pore network. Moreover, applying an initial stiffness reduced by 47\% for the calcite cement results only in a slightly weaker mechanical behaviour. Using the quantitative approach introduced here substantially improves the accuracy of predictions in elastic rock properties compared to general analytical methods, and further enables quantification of uncertainties related to spatial variations in porosity and mineral distribution.},
  language  = {en}
}
@article{WetzelKempkaKuehn2021,
  author    = {Wetzel, Maria and Kempka, Thomas and K{\"u}hn, Michael},
  title     = {Diagenetic trends of synthetic reservoir sandstone properties assessed by digital rock physics},
  series = {Minerals},
  volume    = {11},
  journal   = {Minerals},
  number    = {2},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2075-163X},
  doi       = {10.3390/min11020151},
  pages     = {21},
  year      = {2021},
  abstract  = {Quantifying interactions and dependencies among geometric, hydraulic and mechanical properties of reservoir sandstones is of particular importance for the exploration and utilisation of the geological subsurface and can be assessed by synthetic sandstones comprising the microstructural complexity of natural rocks. In the present study, three highly resolved samples of the Fontainebleau, Berea and Bentheim sandstones are generated by means of a process-based approach, which combines the gravity-driven deposition of irregularly shaped grains and their diagenetic cementation by three different schemes. The resulting evolution in porosity, permeability and rock stiffness is examined and compared to the respective micro-computer tomographic (micro-CT) scans. The grain contact-preferential scheme implies a progressive clogging of small throats and consequently produces considerably less connected and stiffer samples than the two other schemes. By contrast, uniform quartz overgrowth continuously alters the pore space and leads to the lowest elastic properties. The proposed stress-dependent cementation scheme combines both approaches of contact-cement and quartz overgrowth, resulting in granulometric, hydraulic and elastic properties equivalent to those of the respective micro-CT scans, where bulk moduli slightly deviate by 0.8\%, 4.9\% and 2.5\% for the Fontainebleau, Berea and Bentheim sandstone, respectively. The synthetic samples can be further altered to examine the impact of mineral dissolution or precipitation as well as fracturing on various petrophysical correlations, which is of particular relevance for numerous aspects of a sustainable subsurface utilisation.},
  language  = {en}
}
@incollection{WeylandPallastTiberius2022,
  author    = {Weyland, Michael and Pallast, Gregor and Tiberius, Victor},
  title     = {{\"O}konomisches Denken f{\"o}rdern durch kognitiv aktivierende Aufgaben},
  series = {{\"O}konomisches Denken lehren und lernen},
  booktitle = {{\"O}konomisches Denken lehren und lernen},
  editor    = {Brahm, Taiga and Iberer, Ulrich and K{\"a}rner, Tobias and Weyland, Michael},
  publisher = {wbv},
  address   = {Bielefeld},
  isbn      = {978-3-7639-7048-3},
  doi       = {10.3278/9783763973088_25},
  pages     = {26 -- 48},
  year      = {2022},
  abstract  = {In diesem Beitrag m{\"o}chten wir einen Gedanken des amerikanischen Mathematikers Paul Halmos aufgreifen und konkretisieren. Wir m{\"o}chten verdeutlichen, dass {\"o}konomisches Denken nicht abstrakt gelehrt, sondern „erfahren" werden muss, wenn es nachhaltig und in seiner ganzen Breite gef{\"o}rdert werden soll. Dazu dienen kognitiv aktivierende Aufgaben. Was man darunter versteht und welche Funktionen und Qualit{\"a}tsmerkmale Aufgaben in der {\"o}konomischen Bildung besitzen, verdeutlichen wir in den Abschnitten 1 und 2. Im Praxisteil (Abschnitte 3 bis 8) werden konkrete, unterrichtlich erprobte Beispielaufgaben vorgestellt, mit denen {\"o}konomisches Denken erfolgreich gef{\"o}rdert werden kann. Unser Beitrag schließt mit einer kurzen Skizze wirtschaftsdidaktischer Implikationen (Abschnitt 9).},
  language  = {de}
}
@article{WeymarZaehle2021,
  author    = {Weymar, Mathias and Z{\"a}hle, Tino},
  title     = {Editorial: New frontiers in noninvasive brain stimulation},
  series = {Frontiers in psychology / Frontiers Research Foundation},
  volume    = {12},
  journal   = {Frontiers in psychology / Frontiers Research Foundation},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2021.694723},
  pages     = {2},
  year      = {2021},
  language  = {en}
}
@article{WeyrichGuerreroAltamiranoYasaretal.2022,
  author    = {Weyrich, Alexandra and Guerrero-Altamirano, Tania P. and Yasar, Selma and Czirjak, G{\´a}bor-{\´A}rp{\´a}d and Wachter, Bettina and Fickel, J{\"o}rns},
  title     = {First Steps towards the development of epigenetic biomarkers in female cheetahs (Acinonyx jubatus)},
  series = {Life : open access journal},
  volume    = {12},
  journal   = {Life : open access journal},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2075-1729},
  doi       = {10.3390/life12060920},
  pages     = {16},
  year      = {2022},
  abstract  = {Free-ranging cheetahs (Acinonyx jubatus) are generally healthy, whereas cheetahs under human care, such as those in zoological gardens, suffer from ill-defined infectious and degenerative pathologies. These differences are only partially explained by husbandry management programs because both groups share low genetic diversity. However, mounting evidence suggests that physiological differences between populations in different environments can be tracked down to differences in epigenetic signatures. Here, we identified differentially methylated regions (DMRs) between free-ranging cheetahs and conspecifics in zoological gardens and prospect putative links to pathways relevant to immunity, energy balance and homeostasis. Comparing epigenomic DNA methylation profiles obtained from peripheral blood mononuclear cells (PBMCs) from eight free-ranging female cheetahs from Namibia and seven female cheetahs living in zoological gardens within Europe, we identified DMRs of which 22 were hypermethylated and 23 hypomethylated. Hypermethylated regions in cheetahs under human care were located in the promoter region of a gene involved in host-pathogen interactions (KLC1) and in an intron of a transcription factor relevant for the development of pancreatic beta-cells, liver, and kidney (GLIS3). The most canonical mechanism of DNA methylation in promoter regions is assumed to repress gene transcription. Taken together, this could indicate that hypermethylation at the promoter region of KLC1 is involved in the reduced immunity in cheetahs under human care. This approach can be generalized to characterize DNA methylation profiles in larger cheetah populations under human care with a more granular longitudinal data collection, which, in the future, could be used to monitor the early onset of pathologies, and ultimately translate into the development of biomarkers with prophylactic and/or therapeutic potential.},
  language  = {en}
}
@article{WeyrichJeschekSchrapersetal.2018,
  author    = {Weyrich, Alexandra and Jeschek, Marie and Schrapers, Katharina T. and Lenz, Dorina and Chung, Tzu Hung and Ruebensam, Kathrin and Yasar, Sermin and Schneemann, Markus and Ortmann, Sylvia and Jewgenow, Katarina and Fickel, J{\"o}rns},
  title     = {Diet changes alter paternally inherited epigenetic pattern in male Wild guinea pigs},
  series = {Environmental Epigenetics},
  volume    = {4},
  journal   = {Environmental Epigenetics},
  number    = {2},
  publisher = {Oxford Univ. Press},
  address   = {Oxford},
  issn      = {2058-5888},
  doi       = {10.1093/eep/dvy011},
  pages     = {12},
  year      = {2018},
  abstract  = {Epigenetic modifications, of which DNA methylation is the most stable, are a mechanism conveying environmental information to subsequent generations via parental germ lines. The paternal contribution to adaptive processes in the offspring might be crucial, but has been widely neglected in comparison to the maternal one. To address the paternal impact on the offspring's adaptability to changes in diet composition, we investigated if low protein diet (LPD) in F0 males caused epigenetic alterations in their subsequently sired sons. We therefore fed F0 male Wild guinea pigs with a diet lowered in protein content (LPD) and investigated DNA methylation in sons sired before and after their father's LPD treatment in both, liver and testis tissues. Our results point to a 'heritable epigenetic response' of the sons to the fathers' dietary change. Because we detected methylation changes also in the testis tissue, they are likely to be transmitted to the F2 generation. Gene-network analyses of differentially methylated genes in liver identified main metabolic pathways indicating a metabolic reprogramming ('metabolic shift'). Epigenetic mechanisms, allowing an immediate and inherited adaptation may thus be important for the survival of species in the context of a persistently changing environment, such as climate change.},
  language  = {en}
}
@article{WeyrichLenzFickel2018,
  author    = {Weyrich, Alexandra and Lenz, Dorina and Fickel, J{\"o}rns},
  title     = {Environmental Change-Dependent Inherited Epigenetic Response},
  series = {GENES},
  volume    = {10},
  journal   = {GENES},
  number    = {1},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4425},
  doi       = {10.3390/genes10010004},
  pages     = {15},
  year      = {2018},
  abstract  = {Epigenetic modifications are a mechanism conveying environmental information to subsequent generations via parental germ lines. Research on epigenetic responses to environmental changes in wild mammals has been widely neglected, as well as studies that compare responses to changes in different environmental factors. Here, we focused on the transmission of DNA methylation changes to naive male offspring after paternal exposure to either diet (~40\% less protein) or temperature increase (10 °C increased temperature). Because both experiments focused on the liver as the main metabolic and thermoregulation organ, we were able to decipher if epigenetic changes differed in response to different environmental changes. Reduced representation bisulfite sequencing (RRBS) revealed differentially methylated regions (DMRs) in annotated genomic regions in sons sired before (control) and after the fathers' treatments. We detected both a highly specific epigenetic response dependent on the environmental factor that had changed that was reflected in genes involved in specific metabolic pathways, and a more general response to changes in outer stimuli reflected by epigenetic modifications in a small subset of genes shared between both responses. Our results indicated that fathers prepared their offspring for specific environmental changes by paternally inherited epigenetic modifications, suggesting a strong paternal contribution to adaptive processes.},
  language  = {en}
}
@article{WichaHuisingaKloft2017,
  author    = {Wicha, Sebastian G. and Huisinga, Wilhelm and Kloft, Charlotte},
  title     = {Translational pharmacometric evaluation of typical antibiotic broad-spectrum combination therapies against staphylococcus aureus exploiting in vitro information},
  series = {CPT: pharmacometrics \& systems pharmacology},
  volume    = {6},
  journal   = {CPT: pharmacometrics \& systems pharmacology},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {2163-8306},
  doi       = {10.1002/psp4.12197},
  pages     = {512 -- 522},
  year      = {2017},
  abstract  = {Broad-spectrum antibiotic combination therapy is frequently applied due to increasing resistance development of infective pathogens. The objective of the present study was to evaluate two common empiric broad-spectrum combination therapies consisting of either linezolid (LZD) or vancomycin (VAN) combined with meropenem (MER) against Staphylococcus aureus (S. aureus) as the most frequent causative pathogen of severe infections. A semimechanistic pharmacokinetic-pharmacodynamic (PK-PD) model mimicking a simplified bacterial life-cycle of S. aureus was developed upon time-kill curve data to describe the effects of LZD, VAN, and MER alone and in dual combinations. The PK-PD model was successfully (i) evaluated with external data from two clinical S. aureus isolates and further drug combinations and (ii) challenged to predict common clinical PK-PD indices and breakpoints. Finally, clinical trial simulations were performed that revealed that the combination of VAN-MER might be favorable over LZD-MER due to an unfavorable antagonistic interaction between LZD and MER.},
  language  = {en}
}
@article{WickKriemlerGranacher2022,
  author    = {Wick, Kristin and Kriemler, Susi and Granacher, Urs},
  title     = {Associations between measures of physical fitness and cognitive performance in preschool children},
  series = {BMC sports science, medicine \& rehabilitation},
  volume    = {14},
  journal   = {BMC sports science, medicine \& rehabilitation},
  number    = {1},
  publisher = {BMC},
  address   = {London},
  issn      = {2052-1847},
  doi       = {10.1186/s13102-022-00470-w},
  pages     = {8},
  year      = {2022},
  abstract  = {Background: Given that recent studies report negative secular declines in physical fitness, associations between fitness and cognition in childhood are strongly discussed. The preschool age is characterized by high neuroplasticity which effects motor skill learning, physical fitness, and cognitive development. The aim of this study was to assess the relation of physical fitness and attention (including its individual dimensions (quantitative, qualitative)) as one domain of cognitive performance in preschool children. We hypothesized that fitness components which need precise coordination compared to simple fitness components are stronger related to attention. Methods: Physical fitness components like static balance (i.e., single-leg stance), muscle strength (i.e., handgrip strength), muscle power (i.e., standing long jump), and coordination (i.e., hopping on one leg) were assessed in 61 healthy children (mean age 4.5 +/- 0.6 years; girls n = 30). Attention was measured with the "Konzentrations-Handlungsverfahren fur Vorschulkinder" [concentration-action procedure for preschoolers]). Analyses were adjusted for age, body height, and body mass. Results: Results from single linear regression analysis revealed a significant (p < 0.05) association between physical fitness (composite score) and attention (composite score) (standardized ss = 0.40), showing a small to medium effect (F-2 = 0.14). Further, coordination had a significant relation with the composite score and the quantitative dimension of attention (standardized ss = 0.35; p < 0.01; standardized ss = - 0.33; p < 0.05). Coordination explained about 11\% (composite score) and 9\% (quantitative dimension) of the variance in the stepwise multiple regression model. Conclusion: The results indicate that performance in physical fitness, particularly coordination, is related to attention in preschool children. Thus, high performance in complex fitness components (i.e., hopping on one leg) tends to predict attention in preschool children. Further longitudinal studies should focus on the effectiveness of physical activity programs implementing coordination and complex exercises at preschool age to examine cause-effect relationships between physical fitness and attention precisely.},
  language  = {en}
}
@article{WickertSchildgen2019,
  author    = {Wickert, Andrew D. and Schildgen, Taylor F.},
  title     = {Long-profile evolution of transport-limited gravel-bed rivers},
  series = {Earth surface dynamics},
  volume    = {7},
  journal   = {Earth surface dynamics},
  number    = {1},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {2196-6311},
  doi       = {10.5194/esurf-7-17-2019},
  pages     = {17 -- 43},
  year      = {2019},
  abstract  = {Alluvial and transport-limited bedrock rivers constitute the majority of fluvial systems on Earth. Their long profiles hold clues to their present state and past evolution. We currently possess first-principles-based governing equations for flow, sediment transport, and channel morphodynamics in these systems, which we lack for detachment-limited bedrock rivers. Here we formally couple these equations for transport-limited gravel-bed river long-profile evolution. The result is a new predictive relationship whose functional form and parameters are grounded in theory and defined through experimental data. From this, we produce a power-law analytical solution and a finite-difference numerical solution to long-profile evolution. Steady-state channel concavity and steepness are diagnostic of external drivers: concavity decreases with increasing uplift rate, and steepness increases with an increasing sediment-to-water supply ratio. Constraining free parameters explains common observations of river form: to match observed channel concavities, gravel-sized sediments must weather and fine - typically rapidly - and valleys typically should widen gradually. To match the empirical square-root width-discharge scaling in equilibrium-width gravel-bed rivers, downstream fining must occur. The ability to assign a cause to such observations is the direct result of a deductive approach to developing equations for landscape evolution.},
  language  = {en}
}
@article{WiebelerVollbrechtNeubaetal.2021,
  author    = {Wiebeler, Christian and Vollbrecht, Joachim and Neuba, Adam and Kitzerow, Heinz and Schumacher, Stefan},
  title     = {Unraveling the electrochemical and spectroscopic properties of neutral and negatively charged perylene tetraethylesters},
  series = {Scientific reports},
  volume    = {11},
  journal   = {Scientific reports},
  number    = {1},
  publisher = {Macmillan Publishers Limited, part of Springer Nature},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-021-95551-0},
  pages     = {11},
  year      = {2021},
  abstract  = {A detailed investigation of the energy levels of perylene-3,4,9,10-tetracarboxylic tetraethylester as a representative compound for the whole family of perylene esters was performed. It was revealed via electrochemical measurements that one oxidation and two reductions take place. The bandgaps determined via the electrochemical approach are in good agreement with the optical bandgap obtained from the absorption spectra via a Tauc plot. In addition, absorption spectra in dependence of the electrochemical potential were the basis for extensive quantum-chemical calculations of the neutral, monoanionic, and dianionic molecules. For this purpose, calculations based on density functional theory were compared with post-Hartree-Fock methods and the CAM-B3LYP functional proved to be the most reliable choice for the calculation of absorption spectra. Furthermore, spectral features found experimentally could be reproduced with vibronic calculations and allowed to understand their origins. In particular, the two lowest energy absorption bands of the anion are not caused by absorption of two distinct electronic states, which might have been expected from vertical excitation calculations, but both states exhibit a strong vibronic progression resulting in contributions to both bands.},
  language  = {en}
}
@article{Wieber2020,
  author    = {Wieber, Anja},
  title     = {Die palmyrenische K{\"o}nigin Zenobia als Werbeikone f{\"u}r Seife},
  series = {PaRDeS : Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien = Transformative Translations in Jewish History and Culture},
  volume    = {2020},
  journal   = {PaRDeS : Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien = Transformative Translations in Jewish History and Culture},
  number    = {11},
  editor    = {Amb{\"u}hl, Annemarie},
  issn      = {2364-7612},
  doi       = {https://doi.org/10.34679/thersites.vol11.169},
  pages     = {277 -- 323},
  year      = {2020},
  abstract  = {This article analyses, as an example of the advertising of cosmetic products, a campaign launched by the US-American company "Johnson Soap" for their product, the facial soap "Palmolive". Examining its ads of 1911 in which certain ancient exempla are employed, it becomes clear that the Palmyrene queen Zenobia and with her the semi-historical Semiramis and the more mythical Dido are aligned to the "1001 Nights" character Scheherazade. Since they are jointly labelled as "historically famous oriental queens" and because of the reference to Zenobia's white skin, they fall into the fantasy of fair-skinned harem women and evoke thoughts of all the pleasures and comforts of the luxurious Orient. To the modern female customer of 1900 (well steeped in the knowledge of those ancient characters) Zenobia and the other exempla should serve as celebrities worth emulating. Above all they are deemed to be beautiful, and experts in cosmetics which would guarantee the effect of the product they are standing for. A finding that proves to be valid even in an advertising concept of today for the Syrian-German "Zhenobya-soap".},
  language  = {de}
}
@article{WiebkingLinWippert2022,
  author    = {Wiebking, Christine and Lin, Chiao-I and Wippert, Pia-Maria},
  title     = {Training intervention effects on cognitive performance and neuronal plasticity — A pilot study},
  series = {Frontiers in Neurology, section Neurorehabilitation},
  volume    = {13},
  journal   = {Frontiers in Neurology, section Neurorehabilitation},
  publisher = {Frontiers},
  address   = {Lausanne, Schweiz},
  issn      = {1664-2295},
  doi       = {10.3389/fneur.2022.773813},
  pages     = {11},
  year      = {2022},
  abstract  = {Studies suggest that people suffering from chronic pain may have altered brain plasticity, along with altered functional connectivity between pain-processing brain regions. These may be related to decreased mood and cognitive performance. There is some debate as to whether physical activity combined with behavioral therapy (e.g. cognitive distraction, body scan) may counteract these changes. However, underlying neuronal mechanisms are unclear. The aim of the current pilot study with a 3-armed randomized controlled trial design was to examine the effects of sensorimotor training for nonspecific chronic low back pain on (1) cognitive performance; (2) fMRI activity co-fluctuations (functional connectivity) between pain-related brain regions; and (3) the relationship between functional connectivity and subjective variables (pain and depression). Six hundred and sixty two volunteers with non-specific chronic low back pain were randomly allocated to a unimodal (sensorimotor training), multidisciplinary (sensorimotor training and behavioral therapy) intervention, or to a control group within a multicenter study. A subsample of patients (n = 21) from one study center participated in the pilot study presented here. Measurements were at baseline, during (3 weeks, M2) and after intervention (12 weeks, M4 and 24 weeks, M5). Cognitive performance was measured by the Trail Making Test and functional connectivity by MRI. Pain perception and depression were assessed by the Von Korff questionnaire and the Hospital and Anxiety. Group differences were calculated by univariate and repeated ANOVA measures and Bayesian statistics; correlations by Pearson's r. Change and correlation of functional connection were analyzed within a pooled intervention group (uni-, multidisciplinary group). Results revealed that participants with increased pain intensity at baseline showed higher functional connectivity between pain-related brain areas used as ROIs in this study. Though small sample sizes limit generalization, cognitive performance increased in the multimodal group. Increased functional connectivity was observed in participants with increased pain ratings. Pain ratings and connectivity in pain-related brain regions decreased after the intervention. The results provide preliminary indication that intervention effects can potentially be achieved on the cognitive and neuronal level. The intervention may be suitable for therapy and prevention of non-specific chronic low back pain.},
  language  = {en}
}
@article{WieczorekHerzschuh2020,
  author    = {Wieczorek, Mareike and Herzschuh, Ulrike},
  title     = {Compilation of relative pollen productivity (RPP) estimates and taxonomically harmonised RPP datasets for single continents and Northern Hemisphere extratropics},
  series = {Earth system science data : ESSD},
  volume    = {12},
  journal   = {Earth system science data : ESSD},
  number    = {4},
  publisher = {Copernicus},
  address   = {G{\"o}ttingen},
  issn      = {1866-3508},
  doi       = {10.5194/essd-12-3515-2020},
  pages     = {3515 -- 3528},
  year      = {2020},
  abstract  = {Relative pollen productivity (RPP) estimates are fractionate values, often in relation to Poaceae, that allow vegetation cover to be estimated from pollen counts with the help of models. RPP estimates are especially used in the scientific community in Europe and China, with a few studies in North America. Here we present a comprehensive compilation of available northern hemispheric RPP studies and their results arising from 51 publications with 60 sites and 131 taxa. This compilation allows scientists to identify data gaps in need of further RPP analyses but can also aid them in finding an RPP set for their study region. We also present a taxonomically harmonised, unified RPP dataset for the Northern Hemisphere and subsets for North America (including Greenland), Europe (including arctic Russia), and China, which we generated from the available studies. The unified dataset gives the mean RPP for 55 harmonised taxa as well as fall speeds, which are necessary to reconstruct vegetation cover from pollen counts and RPP values. Data are openly available at https://doi.org/10.1594/PANGAEA.922661 (Wieczorek and Herzschuh, 2020).},
  language  = {en}
}
@article{WiemkerBunovaNeufeldetal.2022,
  author    = {Wiemker, Veronika and Bunova, Anna and Neufeld, Maria and Gornyi, Boris and Yurasova, Elena and Konigorski, Stefan and Kalinina, Anna and Kontsevaya, Anna and Ferreira-Borges, Carina and Probst, Charlotte},
  title     = {Pilot study to evaluate usability and acceptability of the 'Animated Alcohol Assessment Tool' in Russian primary healthcare},
  series = {Digital health},
  volume    = {8},
  journal   = {Digital health},
  publisher = {Sage Publications},
  address   = {London},
  issn      = {2055-2076},
  doi       = {10.1177/20552076211074491},
  pages     = {11},
  year      = {2022},
  abstract  = {Background and aims: Accurate and user-friendly assessment tools quantifying alcohol consumption are a prerequisite to effective prevention and treatment programmes, including Screening and Brief Intervention. Digital tools offer new potential in this field. We developed the 'Animated Alcohol Assessment Tool' (AAA-Tool), a mobile app providing an interactive version of the World Health Organization's Alcohol Use Disorders Identification Test (AUDIT) that facilitates the description of individual alcohol consumption via culturally informed animation features. This pilot study evaluated the Russia-specific version of the Animated Alcohol Assessment Tool with regard to (1) its usability and acceptability in a primary healthcare setting, (2) the plausibility of its alcohol consumption assessment results and (3) the adequacy of its Russia-specific vessel and beverage selection. Methods: Convenience samples of 55 patients (47\% female) and 15 healthcare practitioners (80\% female) in 2 Russian primary healthcare facilities self-administered the Animated Alcohol Assessment Tool and rated their experience on the Mobile Application Rating Scale - User Version. Usage data was automatically collected during app usage, and additional feedback on regional content was elicited in semi-structured interviews. Results: On average, patients completed the Animated Alcohol Assessment Tool in 6:38 min (SD = 2.49, range = 3.00-17.16). User satisfaction was good, with all subscale Mobile Application Rating Scale - User Version scores averaging >3 out of 5 points. A majority of patients (53\%) and practitioners (93\%) would recommend the tool to 'many people' or 'everyone'. Assessed alcohol consumption was plausible, with a low number (14\%) of logically impossible entries. Most patients reported the Animated Alcohol Assessment Tool to reflect all vessels (78\%) and all beverages (71\%) they typically used. Conclusion: High acceptability ratings by patients and healthcare practitioners, acceptable completion time, plausible alcohol usage assessment results and perceived adequacy of region-specific content underline the Animated Alcohol Assessment Tool's potential to provide a novel approach to alcohol assessment in primary healthcare. After its validation, the Animated Alcohol Assessment Tool might contribute to reducing alcohol-related harm by facilitating Screening and Brief Intervention implementation in Russia and beyond.},
  language  = {en}
}
@phdthesis{Wienecke2021,
  author    = {Wienecke, Maik},
  title     = {Wohin mit der sozialistischen Pers{\"o}nlichkeit?},
  series = {Potsdamer Geographische Praxis},
  journal   = {Potsdamer Geographische Praxis},
  number    = {16},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-518-7},
  issn      = {2194-1599},
  doi       = {10.25932/publishup-51591},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-515911},
  school      = {Universit{\"a}t Potsdam},
  pages     = {254},
  year      = {2021},
  abstract  = {Das Schulfach Geographie war in der DDR eines der F{\"a}cher, das sehr stark mit politischen Themen im Sinne des Marxismus-Leninismus best{\"u}ckt war. Ein anderer Aspekt sind die sozialistischen Erziehungsziele, die in der Schulbildung der DDR hoch im Kurs standen. Im Fokus stand diesbez{\"u}glich die Erziehung der Kinder zu sozialistischen Pers{\"o}nlichkeiten. Die Arbeit versucht einen klaren Blick auf diesen Umstand zu werfen, um zu erfahren, was da von den Lehrkr{\"a}ften gefordert wurde und wie es in der Schule umzusetzen war. Durch den Fall der Mauer war nat{\"u}rlich auch eine Umstrukturierung des Bildungssystems im Osten unausweichlich. Hier will die Arbeit Einblicke geben, wie die Geographielehrkr{\"a}fte diese Transformation mitgetragen und umgesetzt haben. Welche Wesensz{\"u}ge aus der Sozialisierung in der DDR haben sich bei der Gestaltung des Unterrichtes und dessen Ausrichtung auf die neuen Erziehungsziele erhalten? Hierzu wurden Geographielehrkr{\"a}fte befragt, die sowohl in der DDR als auch im geeinten Deutschland unterrichtet haben. Die Fragen bezogen sich in erster Linie auf die Art und Weise des Unterrichtens vor, w{\"a}hrend und nach der Wende und der daraus entstandenen Systemtransformation. Die Befragungen kommen zu dem Ergebnis, dass sich der Geographieunterricht in der DDR thematisch von dem in der BRD nicht sonderlich unterschied. Von daher bedurfte es keiner umfangreichen inhaltlichen Ver{\"a}nderung des Geographieunterrichts. Schon zu DDR-Zeiten wurden durch die Lehrkr{\"a}fte offenbar eigenm{\"a}chtig ideologiefreie physisch-geographische Themen oft ausgedehnt, um die Ideologie des Faches zu reduzieren. So fiel den meisten eine Anpassung ihres Unterrichts an das westdeutsche System relativ leicht. Die humanistisch gepr{\"a}gte Werteerziehung des DDR-Bildungssystems wurde unter Ausklammerung des sozialistischen Aspektes ebenso fortgef{\"u}hrt, da es auch hier viele Parallelen zum westdeutschen System gegeben hat. Deutlich wird eine Charakterisierung des Faches als Naturwissenschaft von Seiten der ostdeutschen Lehrkr{\"a}fte, obwohl das Fach an den Schulen den Gesellschaftswissenschaften zugeordnet wird und auch in der DDR eine starke wirtschaftsgeographische Ausrichtung hatte. Von der Verantwortung sozialistische Pers{\"o}nlichkeiten zu erziehen, wurden die Lehrkr{\"a}fte mit dem Ende der DDR entbunden und die in dieser Arbeit aufgef{\"u}hrten Interviewausz{\"u}ge lassen keinen Zweifel daran, dass es dem Großteil der Befragten darum nicht leidtat, sie sich aber bis heute an der Werteorientierung aus DDR-Zeiten orientieren.},
  language  = {de}
}
@article{Wienfort2023,
  author    = {Wienfort, Monika},
  title     = {Die Preußische Seehandlung im Lexikon im 19. Jahrhundert},
  series = {Die Preußische Seehandlung zwischen Markt, Staat und Kultur : 40 Jahre Stiftung Preußische Seehandlung},
  journal   = {Die Preußische Seehandlung zwischen Markt, Staat und Kultur : 40 Jahre Stiftung Preußische Seehandlung},
  editor    = {Wienfort, Monika},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-562-0},
  doi       = {10.25932/publishup-59990},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-599907},
  pages     = {129 -- 150},
  year      = {2023},
  abstract  = {Im 19. Jahrhundert waren Konversationslexika, wie der Name schon andeutet, dazu gedacht, die Konversation in Salon und Vereinen mit Informationen zu bereichern. In den einzelnen Artikeln wurde auf Pr{\"a}zision, Genauigkeit und {\"U}berpr{\"u}fbarkeit gesetzt, um der Leserschaft auch ein eigenes Urteil zu erm{\"o}glichen. Die „Seehandlungs-Societ{\"a}t in Preußen" oder „Seehandlung, preußische", wie sie in deutschen Lexika vorkommt, wandelte sich im 19. Jahrhundert zur Staatsbank. In der ersten H{\"a}lfte des 19. Jahrhunderts fielen die Urteile der Lexika meist ablehnend aus: Die Seehandlung erschien als eine wirtschaftspolitisch katastrophale Fehlentwicklung. Eine besondere Rolle spielte der Pr{\"a}sident Christian (von) Rother, der die Seehandlung zum selbst{\"a}ndigen Unternehmen gemacht hatte. Der Wandel der allgemeinen Lexika in der zweiten H{\"a}lfte des 19. Jahrhunderts ver{\"a}nderte auch die Sicht auf die Seehandlung. Die Gesch{\"a}fte der Bank wurden positiv hervorgehoben, die Beurteilungen verwiesen auf Statistiken und Bilanzen. Der Fokus r{\"u}ckte von den leitenden Personen der Seehandlung hin zum Kampf um Handelsmonopole und den preußischen Landtag als {\"o}ffentlichem Forum. Das vernichtende Urteil der ersten H{\"a}lfte des 19. Jahrhunderts war einer differenzierten Bewertung der Bankent{\"a}tigkeit gewichen.},
  language  = {de}
}
@article{WiepkeMiklashevsky2021,
  author    = {Wiepke, Axel P. and Miklashevsky, Alex},
  title     = {Imaginary Worlds and Their Borders: An Opinion Article},
  series = {Frontiers Media SA},
  volume    = {12},
  journal   = {Frontiers Media SA},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne, Schweiz},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2021.793764},
  pages     = {1 -- 2},
  year      = {2021},
  language  = {en}
}
@article{WieseAlexiadouAllenetal.2022,
  author    = {Wiese, Heike and Alexiadou, Artemis and Allen, Shanley and Bunk, Oliver and Gagarina, Natalia and Iefremenko, Kateryna and Martynova, Maria and Pashkova, Tatiana and Rizou, Vicky and Schroeder, Christoph and Shadrova, Anna and Szucsich, Luka and Tracy, Rosemarie and Tsehaye, Wintai and Zerbian, Sabine and Zuban, Yulia},
  title     = {Heritage speakers as part of the native language continuum},
  series = {Frontiers in psychology},
  volume    = {12},
  journal   = {Frontiers in psychology},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {1664-1078},
  doi       = {10.3389/fpsyg.2021.717973},
  pages     = {19},
  year      = {2022},
  abstract  = {We argue for a perspective on bilingual heritage speakers as native speakers of both their languages and present results from a large-scale, cross-linguistic study that took such a perspective and approached bilinguals and monolinguals on equal grounds. We targeted comparable language use in bilingual and monolingual speakers, crucially covering broader repertoires than just formal language. A main database was the open-access RUEG corpus, which covers comparable informal vs. formal and spoken vs. written productions by adolescent and adult bilinguals with heritage-Greek, -Russian, and -Turkish in Germany and the United States and with heritage-German in the United States, and matching data from monolinguals in Germany, the United States, Greece, Russia, and Turkey. Our main results lie in three areas. (1) We found non-canonical patterns not only in bilingual, but also in monolingual speakers, including patterns that have so far been considered absent from native grammars, in domains of morphology, syntax, intonation, and pragmatics. (2) We found a degree of lexical and morphosyntactic inter-speaker variability in monolinguals that was sometimes higher than that of bilinguals, further challenging the model of the streamlined native speaker. (3) In majority language use, non-canonical patterns were dominant in spoken and/or informal registers, and this was true for monolinguals and bilinguals. In some cases, bilingual speakers were leading quantitatively. In heritage settings where the language was not part of formal schooling, we found tendencies of register leveling, presumably due to the fact that speakers had limited access to formal registers of the heritage language. Our findings thus indicate possible quantitative differences and different register distributions rather than distinct grammatical patterns in bilingual and monolingual speakers. This supports the integration of heritage speakers into the native-speaker continuum. Approaching heritage speakers from this perspective helps us to better understand the empirical data and can shed light on language variation and change in native grammars. Furthermore, our findings for monolinguals lead us to reconsider the state-of-the art on majority languages, given recurring evidence for non-canonical patterns that deviate from what has been assumed in the literature so far, and might have been attributed to bilingualism had we not included informal and spoken registers in monolinguals and bilinguals alike.},
  language  = {en}
}
@article{WiesmeierDalinWehrleetal.2017,
  author    = {Wiesmeier, Isabella K. and Dalin, Daniela and Wehrle, Anja and Granacher, Urs and Muehlbauer, Thomas and Dietterle, J{\"o}rg and Weiller, Cornelius and Gollhofer, Albert and Maurer, Christoph},
  title     = {Balance training enhances vestibular function and reduces overactive proprioceptive feedback in elderly},
  series = {Frontiers in aging neuroscience},
  volume    = {9},
  journal   = {Frontiers in aging neuroscience},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1663-4365},
  doi       = {10.3389/fnagi.2017.00273},
  pages     = {13},
  year      = {2017},
  abstract  = {Objectives: Postural control in elderly people is impaired by degradations of sensory, motor, and higher-level adaptive mechanisms. Here, we characterize the effects of a progressive balance training programon these postural control impairments using a brain network model based on system identification techniques. Methods and Material: We analyzed postural control of 35 healthy elderly subjects and compared findings to data from 35 healthy young volunteers. Eighteen elderly subjects performed a 10 week balance training conducted twice per week. Balance training was carried out in static and dynamic movement states, on support surfaces with different elastic compliances, under different visual conditions and motor tasks. Postural control was characterized by spontaneous sway and postural reactions to pseudorandom anterior-posterior tilts of the support surface. Data were interpreted using a parameter identification procedure based on a brain network model. Conclusion: Balance training reduced overactive proprioceptive feedback and restored vestibular orientation in elderly. Based on the assumption of a linear deterioration of postural control across the life span, the training effect can be extrapolated as a juvenescence of 10 years. This study points to a considerable benefit of a continuous balance training in elderly, even without any sensorimotor deficits.},
  language  = {en}
}
@article{WiesnerLadyman2021,
  author    = {Wiesner, Karoline and Ladyman, James},
  title     = {Complex systems are always correlated but rarely information processing},
  series = {Journal of physics. Complexity},
  volume    = {2},
  journal   = {Journal of physics. Complexity},
  number    = {4},
  publisher = {IOP Publ. Ltd.},
  address   = {Bristol},
  issn      = {2632-072X},
  doi       = {10.1088/2632-072X/ac371c},
  pages     = {4},
  year      = {2021},
  abstract  = {'Complex systems are information processors' is a statement that is frequently made. Here we argue for the distinction between information processing-in the sense of encoding and transmitting a symbolic representation-and the formation of correlations (pattern formation/self-organisation). The study of both uses tools from information theory, but the purpose is very different in each case: explaining the mechanisms and understanding the purpose or function in the first case, versus data analysis and correlation extraction in the latter. We give examples of both and discuss some open questions. The distinction helps focus research efforts on the relevant questions in each case.},
  language  = {en}
}
@article{WilbertBoernertRinglebLueke2022,
  author    = {Wilbert, J{\"u}rgen and B{\"o}rnert-Ringleb, Moritz and L{\"u}ke, Timo},
  title     = {Statistical Power of Piecewise Regression Analyses of Single-Case Experimental Studies Addressing Behavior Problems},
  series = {Frontiers in Education},
  volume    = {7},
  journal   = {Frontiers in Education},
  publisher = {Frontiers Media},
  address   = {Lausanne, Schweiz},
  issn      = {2504-284X},
  doi       = {10.3389/feduc.2022.917944},
  pages     = {1 -- 13},
  year      = {2022},
  abstract  = {In intervention research, single-case experimental designs are an important way to gain insights into the causes of individual changes that yield high internal validity. They are commonly applied to examine the effectiveness of classroom-based interventions to reduce problem behavior in schools. At the same time, there is no consensus on good design characteristics of single-case experimental designs when dealing with behavioral problems in schools. Moreover, specific challenges arise concerning appropriate approaches to analyzing behavioral data. Our study addresses the interplay between the test power of piecewise regression analysis and important design specifications of single-case research designs. Here, we focus on the influence of the following specifications of single-case research designs: number of measurement times, the initial frequency of the behavior, intervention effect, and data trend. We conducted a Monte-Carlo study. First, simulated datasets were created with specific design conditions based on reviews of published single-case intervention studies. Following, data were analyzed using piecewise Poisson-regression models, and the influence of specific design specifications on the test power was investigated. Our results indicate that piecewise regressions have a high potential of adequately identifying the effects of interventions for single-case studies. At the same time, test power is strongly related to the specific design specifications of the single-case study: Few measurement times, especially in phase A, and low initial frequencies of the behavior make it impossible to detect even large intervention effects. Research designs with a high number of measurement times show robust power. The insights gained are highly relevant for researchers in the field, as decisions during the early stage of conceptualizing and planning single-case experimental design studies may impact the chance to identify an existing intervention effect during the research process correctly.},
  language  = {en}
}
@article{WilhelmiGrunwaldGimberetal.2020,
  author    = {Wilhelmi, Ilka and Grunwald, Stephan and Gimber, Niclas and Popp, Oliver and Dittmar, Gunnar and Arumughan, Anup and Wanker, Erich E. and Laeger, Thomas and Schmoranzer, Jan and Daumke, Oliver and Sch{\"u}rmann, Annette},
  title     = {The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic 13-cells},
  series = {Molecular metabolism},
  volume    = {45},
  journal   = {Molecular metabolism},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2212-8778},
  doi       = {10.1016/j.molmet.2020.101151},
  pages     = {13},
  year      = {2020},
  abstract  = {Objective: Hormone secretion from metabolically active tissues, such as pancreatic islets, is governed by specific and highly regulated signaling pathways. Defects in insulin secretion are among the major causes of diabetes. The molecular mechanisms underlying regulated insulin secretion are, however, not yet completely understood. In this work, we studied the role of the GTPase ARFRP1 on insulin secretion from pancreatic 13-cells. <br /> Methods: A 13-cell-specific Arfrp1 knockout mouse was phenotypically characterized. Pulldown experiments and mass spectrometry analysis were employed to screen for new ARFRP1-interacting proteins. Co-immunoprecipitation assays as well as super-resolution microscopy were applied for validation. <br /> Results: The GTPase ARFRP1 interacts with the Golgi-associated PDZ and coiled-coil motif-containing protein (GOPC). Both proteins are co localized at the trans-Golgi network and regulate the first and second phase of insulin secretion by controlling the plasma membrane localization of the SNARE protein SNAP25. Downregulation of both GOPC and ARFRP1 in Min6 cells interferes with the plasma membrane localization of SNAP25 and enhances its degradation, thereby impairing glucose-stimulated insulin release from 13-cells. In turn, overexpression of SNAP25 as well as GOPC restores insulin secretion in islets from 13-cell-specific Arfrp1 knockout mice. <br /> Conclusion: Our results identify a hitherto unrecognized pathway required for insulin secretion at the level of trans-Golgi sorting. (c) 2020 The Authors. Published by Elsevier GmbH. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).},
  language  = {en}
}
@article{WilhelmiNeumannJaehnertetal.2021,
  author    = {Wilhelmi, Ilka and Neumann, Alexander and J{\"a}hnert, Markus and Ouni, Meriem and Sch{\"u}rmann, Annette},
  title     = {Enriched alternative splicing in islets of diabetes-susceptible mice},
  series = {International journal of molecular sciences},
  volume    = {22},
  journal   = {International journal of molecular sciences},
  number    = {16},
  publisher = {Molecular Diversity Preservation International},
  address   = {Basel},
  issn      = {1422-0067},
  doi       = {10.3390/ijms22168597},
  pages     = {16},
  year      = {2021},
  abstract  = {Dysfunctional islets of Langerhans are a hallmark of type 2 diabetes (T2D). We hypothesize that differences in islet gene expression alternative splicing which can contribute to altered protein function also participate in islet dysfunction. RNA sequencing (RNAseq) data from islets of obese diabetes-resistant and diabetes-susceptible mice were analyzed for alternative splicing and its putative genetic and epigenetic modulators. We focused on the expression levels of chromatin modifiers and SNPs in regulatory sequences. We identified alternative splicing events in islets of diabetes-susceptible mice amongst others in genes linked to insulin secretion, endocytosis or ubiquitin-mediated proteolysis pathways. The expression pattern of 54 histones and chromatin modifiers, which may modulate splicing, were markedly downregulated in islets of diabetic animals. Furthermore, diabetes-susceptible mice carry SNPs in RNA-binding protein motifs and in splice sites potentially responsible for alternative splicing events. They also exhibit a larger exon skipping rate, e.g., in the diabetes gene Abcc8, which might affect protein function. Expression of the neuronal splicing factor Srrm4 which mediates inclusion of microexons in mRNA transcripts was markedly lower in islets of diabetes-prone compared to diabetes-resistant mice, correlating with a preferential skipping of SRRM4 target exons. The repression of Srrm4 expression is presumably mediated via a higher expression of miR-326-3p and miR-3547-3p in islets of diabetic mice. Thus, our study suggests that an altered splicing pattern in islets of diabetes-susceptible mice may contribute to an elevated T2D risk.},
  language  = {en}
}
@article{WilhelmsBoersigYangetal.2022,
  author    = {Wilhelms, Andre and B{\"o}rsig, Nicolas and Yang, Jingwei and Holbach, Andreas and Norra, Stefan},
  title     = {Insights into phytoplankton dynamics and water quality monitoring with the BIOFISH at the Elbe River, Germany},
  series = {Water},
  volume    = {14},
  journal   = {Water},
  number    = {13},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2073-4441},
  doi       = {10.3390/w14132078},
  pages     = {20},
  year      = {2022},
  abstract  = {Understanding the key factors influencing the water quality of large river systems forms an important basis for the assessment and protection of cross-regional ecosystems and the implementation of adapted water management concepts. However, identifying these factors requires in-depth comprehension of the unique environmental systems, which can only be achieved by detailed water quality monitoring. Within the scope of the joint science and sports event "Elbschwimmstaffel" (swimming relay on the river Elbe) in June/July 2017 organized by the German Ministry of Education and Research, water quality data were acquired along a 550 km long stretch of the Elbe River in Germany. During the survey, eight physiochemical water quality parameters were recorded in high spatial and temporal resolution with the BIOFISH multisensor system. Multivariate statistical methods were applied to identify and delineate processes influencing the water quality. The BIOFISH dataset revealed that phytoplankton activity has a major impact on the water quality of the Elbe River in the summer months. The results suggest that phytoplankton biomass constitutes a substantial proportion of the suspended particles and that photosynthetic activity of phytoplankton is closely related to significant temporal changes in pH and oxygen saturation. An evaluation of the BIOFISH data based on the combination of statistical analysis with weather and discharge data shows that the hydrological and meteorological history of the sampled water body was the main driver of phytoplankton dynamics. This study demonstrates the capacity of longitudinal river surveys with the BIOFISH or similar systems for water quality assessment, the identification of pollution sources and their utilization for online in situ monitoring of rivers.},
  language  = {en}
}
@article{WilkeBoekerMummetal.2022,
  author    = {Wilke, Liza and Boeker, Sonja and Mumm, Rebecca and Groth, Detlef},
  title     = {The Social status influences human growth},
  series = {Human biology and public health},
  volume    = {2021},
  journal   = {Human biology and public health},
  number    = {3, Summer School Supplement},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  issn      = {2748-9957},
  doi       = {10.52905/hbph2021.3.22},
  pages     = {9},
  year      = {2022},
  abstract  = {Background: In the animal kingdom body size is often linked to dominance and subsequently the standing in social hierarchy. Similarly, human growth has been associated and linked to socioeconomic factors, including one's social status. This has already been proposed in the early 1900s where data on young German school girls from different social strata have been compared. Objectives: This paper aims to summarize and analyze these results and make them accessible for non-German speakers. The full English translation of the historic work of Dikanski (Dikanski, 1914) is available as a supplement. Further, this work aims to compare the historical data with modern references, to test three hypotheses: (1) higher social class is positively associated with body height and weight, (2) affluent people from the used historical data match modern references in weight and height and (3) weight distributions are skewed in both modern and historical populations. Methods: Comparison of historical data from 1914 with WHO and 1980s German data. The data sets, for both body weight and height for 6.0- and 7.0-year-old girls, were fitted onto centile curves and quantile correlation coefficients were calculated. Results: In historical data social status is positively associated with body height and weight while both are also normally distributed, which marks a significant difference to modern references. Conclusion: Social status is positively associated with height, signaling social dominance, making children of affluent classes taller. Children from the historical data do not reach the average height of modern children, even under the best environmental conditions. The children of the upper social class were not skewed in weight distribution, although they had the means to become as obese as modern children.},
  language  = {en}
}
@misc{Wilkens2020,
  type      = {Master Thesis},
  author    = {Wilkens, Jan},
  title     = {"Jewish, Gay and Proud"},
  series = {Pri ha-Pardes},
  journal   = {Pri ha-Pardes},
  number    = {13},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-492-0},
  issn      = {1863-7442},
  doi       = {10.25932/publishup-47370},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-473702},
  school      = {Universit{\"a}t Potsdam},
  pages     = {119},
  year      = {2020},
  abstract  = {This publication examines the foundation and institutional integration of the first gay-lesbian synagogue Beth Chayim Chadashim, which was founded in Los Angeles in 1972. As early as June 1974, the synagogue was admitted to the Union of American Hebrew Congregations, the umbrella organization of the Reform congregations in the United States. Previously, the potential acceptance of a congregation by and for homosexual Jews triggered an intense and broad debate within Reform Judaism. The work asks how it was possible to successfully establish a gay-lesbian synagogue at a time when homosexual acts were considered unnatural and contrary to tradition by almost the entire Jewish community. The starting point of the argumentation is, in addition to general changes in American synagogues after World War II, the assumption that Los Angeles was the most suitable place for this foundation. Los Angeles has an impressive queer history and the Jewish community was more open, tolerant and innovative here than its counterpart on the East Coast. The Metropolitan Community Church was also founded in the city, and as the largest religious institution for homosexual Christians, it also served as the birthplace of queer synagogues. Reform Judaism was chosen as the place of institutional integration of the community because a relative openness for such an endeavor was only seen here. Responsa written in response to a potential admission of Beth Chayim Chadashim can be used to understand the arguments and positions of rabbis and psychologists regarding homosexuality and communities for homosexual Jews in the early 1970s. Ultimately, the commitment and dedication of the congregation and its heterosexual supporters convinced the decision-makers in Reform Judaism. The decisive impulse to question the situation of homosexual Jews in Judaism came from Los Angeles. With its analysis, the publication contributes to the understanding of Queer Jewish History in general and queer synagogues in particular.},
  language  = {en}
}
@article{WilkschAbramova2023,
  author    = {Wilksch, Moritz and Abramova, Olga},
  title     = {PyFin-sentiment},
  series = {International journal of information management data insights},
  volume    = {3},
  journal   = {International journal of information management data insights},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2667-0968},
  doi       = {10.1016/j.jjimei.2023.100171},
  pages     = {10},
  year      = {2023},
  abstract  = {Responding to the poor performance of generic automated sentiment analysis solutions on domain-specific texts, we collect a dataset of 10,000 tweets discussing the topics of finance and investing. We manually assign each tweet its market sentiment, i.e., the investor's anticipation of a stock's future return. Using this data, we show that all existing sentiment models trained on adjacent domains struggle with accurate market sentiment analysis due to the task's specialized vocabulary. Consequently, we design, train, and deploy our own sentiment model. It outperforms all previous models (VADER, NTUSD-Fin, FinBERT, TwitterRoBERTa) when evaluated on Twitter posts. On posts from a different platform, our model performs on par with BERT-based large language models. We achieve this result at a fraction of the training and inference costs due to the model's simple design. We publish the artifact as a python library to facilitate its use by future researchers and practitioners.},
  language  = {en}
}
@article{WillnerGlanemannLevermann2021,
  author    = {Willner, Sven N. and Glanemann, Nicole and Levermann, Anders},
  title     = {Investment incentive reduced by climate damages can be restored by optimal policy},
  series = {Nature Communications},
  volume    = {12},
  journal   = {Nature Communications},
  number    = {1},
  publisher = {Nature Publishing Group UK},
  address   = {London},
  issn      = {2041-1723},
  doi       = {10.1038/s41467-021-23547-5},
  pages     = {9},
  year      = {2021},
  abstract  = {Increasing greenhouse gas emissions are likely to impact not only natural systems but economies worldwide. If these impacts alter future economic development, the financial losses will be significantly higher than the mere direct damages. So far, potentially aggravating investment responses were considered negligible. Here we consistently incorporate an empirically derived temperature-growth relation into the simple integrated assessment model DICE. In this framework we show that, if in the next eight decades varying temperatures impact economic growth as has been observed in the past three decades, income is reduced by similar to 20\% compared to an economy unaffected by climate change. Hereof similar to 40\% are losses due to growth effects of which similar to 50\% result from reduced incentive to invest. This additional income loss arises from a reduced incentive for future investment in anticipation of a reduced return and not from an explicit climate protection policy. Under economically optimal climate-change mitigation, however, optimal investment would only be reduced marginally as mitigation efforts keep returns high.},
  language  = {en}
}
@article{WillnerLevermannZhaoetal.2018,
  author    = {Willner, Sven N. and Levermann, Anders and Zhao, Fang and Frieler, Katja},
  title     = {Adaptation required to preserve future high-end river flood risk at present levels},
  series = {Science Advances},
  volume    = {4},
  journal   = {Science Advances},
  number    = {1},
  publisher = {American Assoc. for the Advancement of Science},
  address   = {Washington},
  issn      = {2375-2548},
  doi       = {10.1126/sciadv.aao1914},
  pages     = {8},
  year      = {2018},
  abstract  = {Earth's surface temperature will continue to rise for another 20 to 30 years even with the strongest carbon emission reduction currently considered. The associated changes in rainfall patterns can result in an increased flood risk worldwide. We compute the required increase in flood protection to keep high-end fluvial flood risk at present levels. The analysis is carried out worldwide for subnational administrative units. Most of the United States, Central Europe, and Northeast and West Africa, as well as large parts of India and Indonesia, require the strongest adaptation effort. More than half of the United States needs to at least double their protection within the next two decades. Thus, the need for adaptation to increased river flood is a global problem affecting industrialized regions as much as developing countries.},
  language  = {en}
}
@article{WinkelbeinerWandtEbertetal.2020,
  author    = {Winkelbeiner, Nicola Lisa and Wandt, Viktoria Klara Veronika and Ebert, Franziska and Lossow, Kristina and Bankoglu, Ezgi E. and Martin, Maximilian and Mangerich, Aswin and Stopper, Helga and Bornhorst, Julia and Kipp, Anna Patricia and Schwerdtle, Tanja},
  title     = {A Multi-Endpoint Approach to Base Excision Repair Incision Activity Augmented by PARylation and DNA Damage Levels in Mice},
  series = {International Journal of Molecular Sciences},
  volume    = {21},
  journal   = {International Journal of Molecular Sciences},
  number    = {18},
  publisher = {Molecular Diversity Preservation International},
  address   = {Basel},
  issn      = {1422-0067},
  doi       = {10.3390/ijms21186600},
  pages     = {19},
  year      = {2020},
  abstract  = {Investigation of processes that contribute to the maintenance of genomic stability is one crucial factor in the attempt to understand mechanisms that facilitate ageing. The DNA damage response (DDR) and DNA repair mechanisms are crucial to safeguard the integrity of DNA and to prevent accumulation of persistent DNA damage. Among them, base excision repair (BER) plays a decisive role. BER is the major repair pathway for small oxidative base modifications and apurinic/apyrimidinic (AP) sites. We established a highly sensitive non-radioactive assay to measure BER incision activity in murine liver samples. Incision activity can be assessed towards the three DNA lesions 8-oxo-2'-deoxyguanosine (8-oxodG), 5-hydroxy-2'-deoxyuracil (5-OHdU), and an AP site analogue. We applied the established assay to murine livers of adult and old mice of both sexes. Furthermore, poly(ADP-ribosyl)ation (PARylation) was assessed, which is an important determinant in DDR and BER. Additionally, DNA damage levels were measured to examine the overall damage levels. No impact of ageing on the investigated endpoints in liver tissue were found. However, animal sex seems to be a significant impact factor, as evident by sex-dependent alterations in all endpoints investigated. Moreover, our results revealed interrelationships between the investigated endpoints indicative for the synergetic mode of action of the cellular DNA integrity maintaining machinery.},
  language  = {en}
}
@inproceedings{WinterBenderAier2024,
  author    = {Winter, Robert and Bender, Benedict and Aier, Stephan},
  title     = {Enterprise-level IS research - need, conceptualization, exemplary knowledge contributions and future opportunities},
  series = {Proceedings of the 57th Annual Hawaii International Conference on System Sciences},
  booktitle = {Proceedings of the 57th Annual Hawaii International Conference on System Sciences},
  editor    = {Bui, Tung X.},
  publisher = {Hawaii International Conference on System Sciences},
  address   = {Honolulu, HI},
  isbn      = {978-0-9981331-7-1},
  pages     = {6402 -- 6411},
  year      = {2024},
  abstract  = {Enterprise solutions, specifically enterprise systems, have allowed companies to integrate enterprises' operations throughout. The integration scope of enterprise solutions has increasingly widened, now often covering customer activities, activities along supply chains, and platform ecosystems. IS research has contributed a wide range of explanatory and design knowledge dealing with this class of IS. During the last two decades, many technological as well as managerial/organizational innovations extended the affordances of enterprise solutions—but this broader scope also challenges traditional approaches to their analysis and design. This position paper presents an enterprise-level (i.e., cross-solution) perspective on IS, discusses the challenges of complexity and coordination for IS design and management, presents selected enterprise-level insights for IS coordination and governance, and explores avenues towards a more comprehensive body of knowledge on this important level of analysis.},
  language  = {en}
}
@article{WippertNiedererDriessleinetal.2020,
  author    = {Wippert, Pia-Maria and Niederer, Daniel and Drießlein, David and Beck, Heidrun and Banzer, Winfried Eberhard and Schneider, Christian and Schiltenwolf, Marcus and Mayer, Frank},
  title     = {Psychosocial Moderators and Mediators of Sensorimotor Exercise in Low Back Pain: A Randomized Multicenter Controlled Trial},
  series = {Frontiers in Psychiatry},
  volume    = {12},
  journal   = {Frontiers in Psychiatry},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne, Schweiz},
  issn      = {1664-0640},
  doi       = {10.3389/fpsyt.2021.629474},
  pages     = {1 -- 16},
  year      = {2020},
  abstract  = {The effects of exercise interventions on unspecific chronic low back pain (CLBP) have been investigated in many studies, but the results are inconclusive regarding exercise types, efficiency, and sustainability. This may be because the influence of psychosocial factors on exercise induced adaptation regarding CLBP is neglected. Therefore, this study assessed psychosocial characteristics, which moderate and mediate the effects of sensorimotor exercise on LBP. A single-blind 3-arm multicenter randomized controlled trial was conducted for 12-weeks. Three exercise groups, sensorimotor exercise (SMT), sensorimotor and behavioral training (SMT-BT), and regular routines (CG) were randomly assigned to 662 volunteers. Primary outcomes (pain intensity and disability) and psychosocial characteristics were assessed at baseline (M1) and follow-up (3/6/12/24 weeks, M2-M5). Multiple regression models were used to analyze whether psychosocial characteristics are moderators of the relationship between exercise and pain, meaning that psychosocial factors and exercise interact. Causal mediation analysis were conducted to analyze, whether psychosocial characteristics mediate the exercise effect on pain. A total of 453 participants with intermittent pain (mean age = 39.5 ± 12.2 years, f = 62\%) completed the training. It was shown, that depressive symptomatology (at M4, M5), vital exhaustion (at M4), and perceived social support (at M5) are significant moderators of the relationship between exercise and the reduction of pain intensity. Further depressive mood (at M4), social-satisfaction (at M4), and anxiety (at M5 SMT) significantly moderate the exercise effect on pain disability. The amount of moderation was of clinical relevance. In contrast, there were no psychosocial variables which mediated exercise effects on pain. In conclusion it was shown, that psychosocial variables can be moderators in the relationship between sensorimotor exercise induced adaptation on CLBP which may explain conflicting results in the past regarding the merit of exercise interventions in CLBP. Results suggest further an early identification of psychosocial risk factors by diagnostic tools, which may essential support the planning of personalized exercise therapy. Level of Evidence: Level I. Clinical Trial Registration: DRKS00004977, LOE: I, MiSpEx: grant-number: 080102A/11-14. https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML\&TRIAL_ID=DRKS00004977.},
  language  = {en}
}
@article{WippertPuertoValenciaDriesslein2022,
  author    = {Wippert, Pia-Maria and Puerto Valencia, Laura and Drießlein, David},
  title     = {Stress and pain},
  series = {Frontiers in medicine},
  volume    = {9},
  journal   = {Frontiers in medicine},
  publisher = {Frontiers Media},
  address   = {Lausanne, Schweiz},
  issn      = {2296-858X},
  doi       = {10.3389/fmed.2022.828954},
  pages     = {14},
  year      = {2022},
  abstract  = {Introduction: Low back pain (LBP) leads to considerable impairment of quality of life worldwide and is often accompanied by psychosomatic symptoms. Objectives: First, to assess the association between stress and chronic low back pain (CLBP) and its simultaneous appearance with fatigue and depression as a symptom triad. Second, to identify the most predictive stress-related pattern set for CLBP for a 1-year diagnosis. Methods: In a 1-year observational study with four measurement points, a total of 140 volunteers (aged 18-45 years with intermittent pain) were recruited. The primary outcomes were pain [characteristic pain intensity (CPI), subjective pain disability (DISS)], fatigue, and depressive mood. Stress was assessed as chronic stress, perceived stress, effort reward imbalance, life events, and physiological markers [allostatic load index (ALI), hair cortisol concentration (HCC)]. Multiple linear regression models and selection procedures for model shrinkage and variable selection (least absolute shrinkage and selection operator) were applied. Prediction accuracy was calculated by root mean squared error (RMSE) and receiver-operating characteristic curves. Results: There were 110 participants completed the baseline assessments (28.2 7.5 years, 38.1\% female), including HCC, and a further of 46 participants agreed to ALI laboratory measurements. Different stress types were associated with LBP, CLBP, fatigue, and depressive mood and its joint occurrence as a symptom triad at baseline; mainly social-related stress types were of relevance. Work-related stress, such as "excessive demands at work"[b = 0.51 (95\%CI -0.23, 1.25), p = 0.18] played a role for upcoming chronic pain disability. "Social overload" [b = 0.45 (95\%CI -0.06, 0.96), p = 0.080] and "over-commitment at work" [b = 0.28 (95\%CI -0.39, 0.95), p = 0.42] were associated with an upcoming depressive mood within 1-year. Finally, seven psychometric (CPI: RMSE = 12.63; DISS: RMSE = 9.81) and five biomarkers (CPI: RMSE = 12.21; DISS: RMSE = 8.94) could be derived as the most predictive pattern set for a 1-year prediction of CLBP. The biomarker set showed an apparent area under the curve of 0.88 for CPI and 0.99 for DISS. Conclusion: Stress disrupts allostasis and favors the development of chronic pain, fatigue, and depression and the emergence of a "hypocortisolemic symptom triad," whereby the social-related stressors play a significant role. For translational medicine, a predictive pattern set could be derived which enables to diagnose the individuals at higher risk for the upcoming pain disorders and can be used in practice.},
  language  = {en}
}
@article{WitteLinnemannstoensHonemannCapitoetal.2021,
  author    = {Witte, Leonie and Linnemannstoens, Karen and Honemann-Capito, Mona and Groß, Julia Christina},
  title     = {Visualization and quantitation of Wg trafficking in the Drosophila wing imaginal epithelium},
  series = {Bio-protocol},
  volume    = {11},
  journal   = {Bio-protocol},
  number    = {11},
  publisher = {bio-protocol.org},
  address   = {Sunnyvale, CA},
  issn      = {2331-8325},
  doi       = {10.21769/BioProtoc.4040},
  pages     = {16},
  year      = {2021},
  abstract  = {Secretory Wnt trafficking can be studied in the polarized epithelial monolayer of Drosophila wing imaginal discs (WID). In this tissue, Wg (Drosophila Wnt-I) is presented on the apical surface of its source cells before being internalized into the endosomal pathway. Long-range Wg secretion and spread depend on secondary secretion from endosomal compartments, but the exact post-endocytic fate of Wg is poorly understood. Here, we summarize and present three protocols for the immunofluorescencebased visualization and quantitation of different pools of intracellular and extracellular Wg in WID: (1) steady-state extracellular Wg; (2) dynamic Wg trafficking inside endosomal compartments; and (3) dynamic Wg release to the cell surface. Using a genetic driver system for gene manipulation specifically at the posterior part of the WID (EnGal4) provides a robust internal control that allows for direct comparison of signal intensities of control and manipulated compartments of the same WID. Therefore, it also circumvents the high degree of staining variability usually associated with whole-tissue samples. In combination with the genetic manipulation of Wg pathway components that is easily feasible in Drosophila, these methods provide a tool-set for the dissection of secretory Wg trafficking and can help us to understand how Wnt proteins travel along endosomal compartments for short-and long-range signal secretion.},
  language  = {en}
}
@article{WittenbecherCuadratJohnstonetal.2022,
  author    = {Wittenbecher, Clemens and Cuadrat, Rafael and Johnston, Luke and Eichelmann, Fabian and J{\"a}ger, Susanne and Kuxhaus, Olga and Prada, Marcela and Del Greco, Fabiola M. and Hicks, Andrew A. and Hoffman, Per and Krumsiek, Jan and Hu, Frank B. and Schulze, Matthias B.},
  title     = {Dihydroceramide- and ceramide-profiling provides insights into human cardiometabolic disease etiology},
  series = {Nature communications},
  volume    = {13},
  journal   = {Nature communications},
  publisher = {Nature Research},
  address   = {Berlin},
  issn      = {2041-1723},
  doi       = {10.1038/s41467-022-28496-1},
  pages     = {13},
  year      = {2022},
  abstract  = {Metabolic alterations precede cardiometabolic disease onset. Here we present ceramide- and dihydroceramide-profiling data from a nested case-cohort (type 2 diabetes [T2D, n = 775]; cardiovascular disease [CVD, n = 551]; random subcohort [n = 1137]) in the prospective EPIC-Potsdam study. We apply the novel NetCoupler-algorithm to link a data-driven (dihydro)ceramide network to T2D and CVD risk. Controlling for confounding by other (dihydro)ceramides, ceramides C18:0 and C22:0 and dihydroceramides C20:0 and C22:2 are associated with higher and ceramide C20:0 and dihydroceramide C26:1 with lower T2D risk. Ceramide C16:0 and dihydroceramide C22:2 are associated with higher CVD risk. Genome-wide association studies and Mendelian randomization analyses support a role of ceramide C22:0 in T2D etiology. Our results also suggest that (dh)ceramides partly mediate the putative adverse effect of high red meat consumption and benefits of coffee consumption on T2D risk. Thus, (dihydro)ceramides may play a critical role in linking genetic predisposition and dietary habits to cardiometabolic disease risk.},
  language  = {en}
}
@article{WittkowskiTaegenerKonarskietal.2020,
  author    = {Wittkowski, Ariane and T{\"a}gener, Judith and Konarski, Michael and Prickett, David James},
  title     = {Das Drei-Felder-Konzept des Selbstlernbereichs am Zessko},
  series = {Potsdamer Beitr{\"a}ge zur Hochschulforschung},
  journal   = {Potsdamer Beitr{\"a}ge zur Hochschulforschung},
  number    = {6},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-498-2},
  issn      = {2192-1075},
  doi       = {10.25932/publishup-49278},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-492789},
  pages     = {143 -- 172},
  year      = {2020},
  abstract  = {Dieser Beitrag erl{\"a}utert, wie die im Teilprojekt entstandenen Selbstlernangebote (Schreibberatung, Vortragscoaching, Sprachtutorien) {\"u}ber die Laufzeit des Teilprojekts (weiter-)entwickelt wurden und wie Studierende durch die Einf{\"u}hrung von neuen, flexibleren Lernformaten (z. B. Einzelberatungen) unterst{\"u}tzt werden. Zudem wird aufgezeigt, wie sich wissenschaftlichen Hilfskr{\"a}ften die M{\"o}glichkeit bietet, sich als Schreibberater/ in, Vortragscoach oder Sprachtutor/in weiterzubilden. Somit wird an der Universit{\"a}t Potsdam nicht nur das Selbstlernen, sondern auch Peer Learning gef{\"o}rdert.},
  language  = {de}
}
@article{Wittram2022,
  author    = {Wittram, Karin},
  title     = {Storyline - eine innovative fach{\"u}bergreifende Methode - auch f{\"u}r den Musikunterricht},
  series = {Perspektiven eines fach{\"u}bergreifenden Musikunterrichts (Potsdamer Schriftenreihe zur Musikp{\"a}dagogik ; 9)},
  journal   = {Perspektiven eines fach{\"u}bergreifenden Musikunterrichts (Potsdamer Schriftenreihe zur Musikp{\"a}dagogik ; 9)},
  number    = {9},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-535-4},
  issn      = {2196-5080},
  doi       = {10.25932/publishup-57063},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-570633},
  pages     = {105 -- 126},
  year      = {2022},
  language  = {de}
}
@article{WitzelAbuRishaAlbersetal.2020,
  author    = {Witzel, Katja and Abu Risha, Marua and Albers, Philip and B{\"o}rnke, Frederik and Hanschen, Franziska S.},
  title     = {Corrigendum : Identification and characterization of three epithiospecifier protein isoforms in Brassica oleracea / Witzel, Katja; Abu Risha, Marua; Albers, Philip; B{\"o}rnke, Frederike; Hanschen, Franziska S. - Lausanne: Frontiers Media, 2019. - Frontiers in plant science : FPLS. - 10 (2019) art. 1552. - doi: 10.3389/fpls.2019.01552},
  series = {Frontiers in plant science : FPLS},
  volume    = {11},
  journal   = {Frontiers in plant science : FPLS},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {1664-462X},
  doi       = {10.3389/fpls.2020.00523},
  pages     = {2},
  year      = {2020},
  language  = {en}
}