@misc{SalzerNoebauer2021, author = {Salzer, Leonhard and N{\"o}bauer, Anna}, title = {(Auf) Humboldts Spuren}, series = {HiN : Alexander von Humboldt im Netz}, volume = {XXII}, journal = {HiN : Alexander von Humboldt im Netz}, number = {43}, editor = {Ette, Ottmar and Knobloch, Eberhard}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {2568-3543}, doi = {10.25932/publishup-53327}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-533271}, pages = {65 -- 82}, year = {2021}, abstract = {Vor seiner Besteigung des Antisana in Ecuador verbrachte Alexander von Humboldt mit seinem Expeditionsteam die Nacht vom 15. auf den 16. M{\"a}rz 1802 in einer Hacienda am Fuße des Vulkangipfels, deren letztes bauliches Zeugnis eine steinerne H{\"u}tte darstellt. Bauforscherische Untersuchungen eines internationalen Forscherteams konnten die mehrschichtige Bau- und Reparaturgeschichte dieses Baudenkmals ermitteln und {\"u}ber eine Auswertung von Reiseberichten mehrerer Andenforscher die Nutzungsgeschichte des einzelnen Geb{\"a}udes und des gesamten Anwesens kl{\"a}ren. Schließlich ergaben sich daraus neue Erkenntnisse zu Humboldts Aufenthalt am Antisana.}, language = {de} } @article{MacdonaldOteroButler2021, author = {Macdonald, Elena and Otero, Noelia and Butler, Tim}, title = {A comparison of long-term trends in observations and emission inventories of NOx}, series = {Atmospheric chemistry and physics / European Geosciences Union}, volume = {21}, journal = {Atmospheric chemistry and physics / European Geosciences Union}, number = {5}, publisher = {Copernicus}, address = {G{\"o}ttingen}, issn = {1680-7316}, doi = {10.5194/acp-21-4007-2021}, pages = {4007 -- 4023}, year = {2021}, abstract = {Air pollution is a pressing issue that is associated with adverse effects on human health, ecosystems, and climate. Despite many years of effort to improve air quality, nitrogen dioxide (NO2) limit values are still regularly exceeded in Europe, particularly in cities and along streets. This study explores how concentrations of nitrogen oxides (NOx = NO + NO2) in European urban areas have changed over the last decades and how this relates to changes in emissions. To do so, the incremental approach was used, comparing urban increments (i.e. urban background minus rural concentrations) to total emissions, and roadside increments (i.e. urban roadside concentrations minus urban background concentrations) to traffic emissions. In total, nine European cities were assessed. The study revealed that potentially confounding factors like the impact of urban pollution at rural monitoring sites through atmospheric transport are generally negligible for NOx. The approach proves therefore particularly useful for this pollutant. The estimated urban increments all showed downward trends, and for the majority of the cities the trends aligned well with the total emissions. However, it was found that factors like a very densely populated surrounding or local emission sources in the rural area such as shipping traffic on inland waterways restrict the application of the approach for some cities. The roadside increments showed an overall very diverse picture in their absolute values and trends and also in their relation to traffic emissions. This variability and the discrepancies between roadside increments and emissions could be attributed to a combination of local influencing factors at the street level and different aspects introducing inaccuracies to the trends of the emis-sion inventories used, including deficient emission factors. Applying the incremental approach was evaluated as useful for long-term pan-European studies, but at the same time it was found to be restricted to certain regions and cities due to data availability issues. The results also highlight that using emission inventories for the prediction of future health impacts and compliance with limit values needs to consider the distinct variability in the concentrations not only across but also within cities.}, language = {en} } @article{WolffGastEversetal.2021, author = {Wolff, Martin and Gast, Klaus and Evers, Andreas and Kurz, Michael and Pfeiffer-Marek, Stefania and Sch{\"u}ler, Anja and Seckler, Robert and Thalhammer, Anja}, title = {A Conserved Hydrophobic Moiety and Helix-Helix Interactions Drive the Self-Assembly of the Incretin Analog Exendin-4}, series = {Biomolecules}, volume = {11}, journal = {Biomolecules}, number = {9}, publisher = {MDPI}, address = {Basel}, issn = {2218-273X}, doi = {10.3390/biom11091305}, pages = {20}, year = {2021}, abstract = {Exendin-4 is a pharmaceutical peptide used in the control of insulin secretion. Structural information on exendin-4 and related peptides especially on the level of quaternary structure is scarce. We present the first published association equilibria of exendin-4 directly measured by static and dynamic light scattering. We show that exendin-4 oligomerization is pH dependent and that these oligomers are of low compactness. We relate our experimental results to a structural hypothesis to describe molecular details of exendin-4 oligomers. Discussion of the validity of this hypothesis is based on NMR, circular dichroism and fluorescence spectroscopy, and light scattering data on exendin-4 and a set of exendin-4 derived peptides. The essential forces driving oligomerization of exendin-4 are helix-helix interactions and interactions of a conserved hydrophobic moiety. Our structural hypothesis suggests that key interactions of exendin-4 monomers in the experimentally supported trimer take place between a defined helical segment and a hydrophobic triangle constituted by the Phe22 residues of the three monomeric subunits. Our data rationalize that Val19 might function as an anchor in the N-terminus of the interacting helix-region and that Trp25 is partially shielded in the oligomer by C-terminal amino acids of the same monomer. Our structural hypothesis suggests that the Trp25 residues do not interact with each other, but with C-terminal Pro residues of their own monomers.}, language = {en} } @article{Ette2021, author = {Ette, Ottmar}, title = {A expuls{\~a}o do {\´E}den}, series = {Literatura e autoritarismo}, journal = {Literatura e autoritarismo}, number = {25}, publisher = {Universidade Federal de Santa Maria (UFSM)}, address = {Santa Maria}, issn = {1679-849X}, doi = {10.5902/1679849X65745}, pages = {5 -- 42}, year = {2021}, abstract = {A tem{\´a}tica da migra{\c{c}}{\~a}o est{\´a} intimamente vinculada {\`a} hist{\´o}ria humana, desde a narrativa b{\´i}blica da expuls{\~a}o do para{\´i}so. O ser humano n{\~a}o apenas empregou t{\´e}cnicas cada vez mais sofisticadas para a viol{\^e}ncia, como tamb{\´e}m transmitiu, atrav{\´e}s dos s{\´e}culos, t{\´e}cnicas de conserva{\c{c}}{\~a}o e uso de seu saberconviver. Nesse sentido m{\´o}vel da hist{\´o}ria, e em conson{\^a}ncia com as literaturas do mundo, a partir de suas diversas origens, {\´e} poss{\´i}vel dizer que existe um "Homo migrans" desde que existe o "Homo sapiens". Assim, {\´e} poss{\´i}vel afirmar que as ideias territoriais ou territorializantes com proveni{\^e}ncia hist{\´o}rico-espacial permitem, vez ou outra, reconhecer seus esfor{\c{c}}os para filtrar e isolar a dimens{\~a}o hist{\´o}rico-m{\´o}vel e vetorial da hist{\´o}ria como narrativa, para tentar construir, com a ajuda de ideias est{\´a}ticas, novos lugares da promessa ou da perda, da abund{\^a}ncia ou da queda.}, language = {pt} } @article{SchwarzKutzinski2021, author = {Schwarz, Ingo and Kutzinski, Vera M.}, title = {A Letter from Alexander von Humboldt to Joseph Albert Wright - Archival Traces}, series = {HiN : Alexander von Humboldt im Netz}, volume = {XXII}, journal = {HiN : Alexander von Humboldt im Netz}, number = {43}, editor = {Ette, Ottmar and Knobloch, Eberhard}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {2568-3543}, doi = {10.25932/publishup-53278}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-532787}, pages = {5 -- 12}, year = {2021}, abstract = {A few months before his death, A. v. Humboldt attended the celebration in honor of the 127th birthday of George Washington at the US legation in Berlin. A letter to the American Envoy, Joseph A. Wright (1810 - 1867), underlines Humboldt's admiration for the fi rst president of the United States. At the same time Humboldt asked the diplomat to mail a letter to the German-American Bernard Moses (1832 - 1897) in Clinton, Louisiana, who had named his son Alexander Humboldt Moses (grave on the Hebrew Rest Cemetery \#2 in New Orleans, burial plot A, 12, 5). It appears to be possible that the Moses family still owns Humboldt's letter.}, language = {en} } @article{FuchsKoenigGerstenberg2021, author = {Fuchs, Susanne and Koenig, Laura L. and Gerstenberg, Annette}, title = {A longitudinal study of speech acoustics in older French females}, series = {Languages : open access journal}, volume = {6}, journal = {Languages : open access journal}, number = {4}, publisher = {MDPI}, address = {Basel}, issn = {2226-471X}, doi = {10.3390/languages6040211}, pages = {24}, year = {2021}, abstract = {Aging in speech production is a multidimensional process. Biological, cognitive, social, and communicative factors can change over time, stay relatively stable, or may even compensate for each other. In this longitudinal work, we focus on stability and change at the laryngeal and supralaryngeal levels in the discourse particle euh produced by 10 older French-speaking females at two times, 10 years apart. Recognizing the multiple discourse roles of euh, we divided out occurrences according to utterance position. We quantified the frequency of euh, and evaluated acoustic changes in formants, fundamental frequency, and voice quality across time and utterance position. Results showed that euh frequency was stable with age. The only acoustic measure that revealed an age effect was harmonics-to-noise ratio, showing less noise at older ages. Other measures mostly varied with utterance position, sometimes in interaction with age. Some voice quality changes could reflect laryngeal adjustments that provide for airflow conservation utterance-finally. The data suggest that aging effects may be evident in some prosodic positions (e.g., utterance-final position), but not others (utterance-initial position). Thus, it is essential to consider the interactions among these factors in future work and not assume that vocal aging is evident throughout the signal.}, language = {en} } @article{RamezaniZiaraniBookhagenSchmidtetal.2021, author = {Ramezani Ziarani, Maryam and Bookhagen, Bodo and Schmidt, Torsten and Wickert, Jens and de la Torre, Alejandro and Deng, Zhiguo and Calori, Andrea}, title = {A model for the relationship between rainfall, GNSS-derived integrated water vapour, and CAPE in the eastern central Andes}, series = {Remote Sensing}, volume = {13}, journal = {Remote Sensing}, number = {18}, publisher = {MDPI}, address = {Basel}, issn = {2072-4292}, doi = {10.3390/rs13183788}, pages = {19}, year = {2021}, abstract = {Atmospheric water vapour content is a key variable that controls the development of deep convective storms and rainfall extremes over the central Andes. Direct measurements of water vapour are challenging; however, recent developments in microwave processing allow the use of phase delays from L-band radar to measure the water vapour content throughout the atmosphere: Global Navigation Satellite System (GNSS)-based integrated water vapour (IWV) monitoring shows promising results to measure vertically integrated water vapour at high temporal resolutions. Previous works also identified convective available potential energy (CAPE) as a key climatic variable for the formation of deep convective storms and rainfall in the central Andes. Our analysis relies on GNSS data from the Argentine Continuous Satellite Monitoring Network, Red Argentina de Monitoreo Satelital Continuo (RAMSAC) network from 1999 to 2013. CAPE is derived from version 2.0 of the ECMWF's (European Centre for Medium-Range Weather Forecasts) Re-Analysis (ERA-interim) and rainfall from the TRMM (Tropical Rainfall Measuring Mission) product. In this study, we first analyse the rainfall characteristics of two GNSS-IWV stations by comparing their complementary cumulative distribution function (CCDF). Second, we separately derive the relation between rainfall vs. CAPE and GNSS-IWV. Based on our distribution fitting analysis, we observe an exponential relation of rainfall to GNSS-IWV. In contrast, we report a power-law relationship between the daily mean value of rainfall and CAPE at the GNSS-IWV station locations in the eastern central Andes that is close to the theoretical relationship based on parcel theory. Third, we generate a joint regression model through a multivariable regression analysis using CAPE and GNSS-IWV to explain the contribution of both variables in the presence of each other to extreme rainfall during the austral summer season. We found that rainfall can be characterised with a higher statistical significance for higher rainfall quantiles, e.g., the 0.9 quantile based on goodness-of-fit criterion for quantile regression. We observed different contributions of CAPE and GNSS-IWV to rainfall for each station for the 0.9 quantile. Fourth, we identify the temporal relation between extreme rainfall (the 90th, 95th, and 99th percentiles) and both GNSS-IWV and CAPE at 6 h time steps. We observed an increase before the rainfall event and at the time of peak rainfall—both for GNSS-integrated water vapour and CAPE. We show higher values of CAPE and GNSS-IWV for higher rainfall percentiles (99th and 95th percentiles) compared to the 90th percentile at a 6-h temporal scale. Based on our correlation analyses and the dynamics of the time series, we show that both GNSS-IWV and CAPE had comparable magnitudes, and we argue to consider both climatic variables when investigating their effect on rainfall extremes.}, language = {en} } @article{GrebenkovMetzlerOshanin2021, author = {Grebenkov, Denis S. and Metzler, Ralf and Oshanin, Gleb}, title = {A molecular relay race: sequential first-passage events to the terminal reaction centre in a cascade of diffusion controlled processes}, series = {New Journal of Physics (NJP)}, volume = {23}, journal = {New Journal of Physics (NJP)}, publisher = {IOP - Institute of Physics Publishing}, address = {Bristol}, issn = {1367-2630}, doi = {10.1088/1367-2630/ac1e42}, pages = {18}, year = {2021}, abstract = {We consider a sequential cascade of molecular first-reaction events towards a terminal reaction centre in which each reaction step is controlled by diffusive motion of the particles. The model studied here represents a typical reaction setting encountered in diverse molecular biology systems, in which, e.g. a signal transduction proceeds via a series of consecutive 'messengers': the first messenger has to find its respective immobile target site triggering a launch of the second messenger, the second messenger seeks its own target site and provokes a launch of the third messenger and so on, resembling a relay race in human competitions. For such a molecular relay race taking place in infinite one-, two- and three-dimensional systems, we find exact expressions for the probability density function of the time instant of the terminal reaction event, conditioned on preceding successful reaction events on an ordered array of target sites. The obtained expressions pertain to the most general conditions: number of intermediate stages and the corresponding diffusion coefficients, the sizes of the target sites, the distances between them, as well as their reactivities are arbitrary.}, language = {en} } @article{PerachAlexandron2021, author = {Perach, Shai and Alexandron, Giora}, title = {A MOOC-Based Computer Science Program for Middle School}, series = {EMOOCs 2021}, volume = {2021}, journal = {EMOOCs 2021}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-512-5}, doi = {10.25932/publishup-51713}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-517133}, pages = {111 -- 127}, year = {2021}, abstract = {In an attempt to pave the way for more extensive Computer Science Education (CSE) coverage in K-12, this research developed and made a preliminary evaluation of a blended-learning Introduction to CS program based on an academic MOOC. Using an academic MOOC that is pedagogically effective and engaging, such a program may provide teachers with disciplinary scaffolds and allow them to focus their attention on enhancing students' learning experience and nurturing critical 21st-century skills such as self-regulated learning. As we demonstrate, this enabled us to introduce an academic level course to middle-school students. In this research, we developed the principals and initial version of such a program, targeting ninth-graders in science-track classes who learn CS as part of their standard curriculum. We found that the middle-schoolers who participated in the program achieved academic results on par with undergraduate students taking this MOOC for academic credit. Participating students also developed a more accurate perception of the essence of CS as a scientific discipline. The unplanned school closure due to the COVID19 pandemic outbreak challenged the research but underlined the advantages of such a MOOCbased blended learning program above classic pedagogy in times of global or local crises that lead to school closure. While most of the science track classes seem to stop learning CS almost entirely, and the end-of-year MoE exam was discarded, the program's classes smoothly moved to remote learning mode, and students continued to study at a pace similar to that experienced before the school shut down.}, language = {en} } @article{KindermannDoblerNiedeggenetal.2021, author = {Kindermann, Liana and Dobler, Magnus and Niedeggen, Daniela and Linst{\"a}dter, Anja}, title = {A new protocol for estimation of woody aboveground biomass in disturbance-prone ecosystems}, series = {Ecological indicators : integrating monitoring, assessment and management}, volume = {135}, journal = {Ecological indicators : integrating monitoring, assessment and management}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1470-160X}, doi = {10.1016/j.ecolind.2021.108466}, pages = {16}, year = {2021}, abstract = {Almost one third of global drylands are open forests and savannas, which are typically shaped by frequent natural disturbances such as wildfire and herbivory. Studies on ecosystem functions and services of woody vegetation require robust estimates of aboveground biomass (AGB). However, most methods have been developed for comparatively undisturbed forest ecosystems. As they are not tailored to accurately quantify AGB of small and irregular growth forms, their application on these growth forms may lead to unreliable or even biased AGB estimates in disturbance-prone dryland ecosystems. Moreover, these methods cannot quantify AGB losses caused by disturbance agents. Here we propose a methodology to estimate individual-and stand-level woody AGB in disturbance-prone ecosystems. It consists of flexible field sampling routines and estimation workflows for six growth classes, delineated by size and damage criteria. It also comprises a detailed damage assessment, harnessing the ecological archive of woody growth for past disturbances. Based on large inventories collected along steep gradients of elephant disturbances in African dryland ecosystems, we compared the AGB estimates generated with our proposed method against estimates from a less adapted forest inventory method. We evaluated the necessary stepwise procedures of method adaptation and analyzed each step's effect on stand-level AGB estimation. We further explored additional advantages of our proposed method with regard to disturbance impact quantification. Results indicate that a majority of growth forms and individuals in savanna vegetation could only be assessed if methods of AGB estimation were adapted to the conditions of a disturbance-prone ecosystem. Furthermore, our damage assessment demonstrated that one third to half of all woody AGB was lost to disturbances. Consequently, less adapted methods may be insufficient and are likely to render inaccurate AGB estimations. Our proposed method has the potential to accurately quantify woody AGB in disturbance-prone ecosystems, as well as AGB losses. Our method is more time consuming than conventional allometric approaches, yet it can cover sufficient areas within reasonable timespans, and can also be easily adapted to alternative sampling schemes.}, language = {en} } @article{GoethelListekMesserschmidtetal.2021, author = {G{\"o}thel, Markus and Listek, Martin and Messerschmidt, Katrin and Schl{\"o}r, Anja and H{\"o}now, Anja and Hanack, Katja}, title = {A New Workflow to Generate Monoclonal Antibodies against Microorganisms}, series = {Applied Sciences}, volume = {11}, journal = {Applied Sciences}, number = {20}, publisher = {MDPI}, address = {Basel}, issn = {1454-5101}, doi = {10.3390/app11209359}, pages = {15}, year = {2021}, abstract = {Monoclonal antibodies are used worldwide as highly potent and efficient detection reagents for research and diagnostic applications. Nevertheless, the specific targeting of complex antigens such as whole microorganisms remains a challenge. To provide a comprehensive workflow, we combined bioinformatic analyses with novel immunization and selection tools to design monoclonal antibodies for the detection of whole microorganisms. In our initial study, we used the human pathogenic strain E. coli O157:H7 as a model target and identified 53 potential protein candidates by using reverse vaccinology methodology. Five different peptide epitopes were selected for immunization using epitope-engineered viral proteins. The identification of antibody-producing hybridomas was performed by using a novel screening technology based on transgenic fusion cell lines. Using an artificial cell surface receptor expressed by all hybridomas, the desired antigen-specific cells can be sorted fast and efficiently out of the fusion cell pool. Selected antibody candidates were characterized and showed strong binding to the target strain E. coli O157:H7 with minor or no cross-reactivity to other relevant microorganisms such as Legionella pneumophila and Bacillus ssp. This approach could be useful as a highly efficient workflow for the generation of antibodies against microorganisms.}, language = {en} } @article{WehrhanSommer2021, author = {Wehrhan, Marc and Sommer, Michael}, title = {A parsimonious approach to estimate soil organic carbon applying Unmanned Aerial System (UAS) multispectral imagery and the topographic position index in a heterogeneous soil landscape}, series = {Remote sensing / Molecular Diversity Preservation International (MDPI)}, volume = {13}, journal = {Remote sensing / Molecular Diversity Preservation International (MDPI)}, number = {18}, publisher = {MDPI}, address = {Basel}, issn = {2072-4292}, doi = {10.3390/rs13183557}, pages = {20}, year = {2021}, abstract = {Remote sensing plays an increasingly key role in the determination of soil organic carbon (SOC) stored in agriculturally managed topsoils at the regional and field scales. Contemporary Unmanned Aerial Systems (UAS) carrying low-cost and lightweight multispectral sensors provide high spatial resolution imagery (<10 cm). These capabilities allow integrate of UAS-derived soil data and maps into digitalized workflows for sustainable agriculture. However, the common situation of scarce soil data at field scale might be an obstacle for accurate digital soil mapping. In our case study we tested a fixed-wing UAS equipped with visible and near infrared (VIS-NIR) sensors to estimate topsoil SOC distribution at two fields under the constraint of limited sampling points, which were selected by pedological knowledge. They represent all releva nt soil types along an erosion-deposition gradient; hence, the full feature space in terms of topsoils' SOC status. We included the Topographic Position Index (TPI) as a co-variate for SOC prediction. Our study was performed in a soil landscape of hummocky ground moraines, which represent a significant of global arable land. Herein, small scale soil variability is mainly driven by tillage erosion which, in turn, is strongly dependent on topography. Relationships between SOC, TPI and spectral information were tested by Multiple Linear Regression (MLR) using: (i) single field data (local approach) and (ii) data from both fields (pooled approach). The highest prediction performance determined by a leave-one-out-cross-validation (LOOCV) was obtained for the models using the reflectance at 570 nm in conjunction with the TPI as explanatory variables for the local approach (coefficient of determination (R-2) = 0.91; root mean square error (RMSE) = 0.11\% and R-2 = 0.48; RMSE = 0.33, respectively). The local MLR models developed with both reflectance and TPI using values from all points showed high correlations and low prediction errors for SOC content (R-2 = 0.88, RMSE = 0.07\%; R-2 = 0.79, RMSE = 0.06\%, respectively). The comparison with an enlarged dataset consisting of all points from both fields (pooled approach) showed no improvement of the prediction accuracy but yielded decreased prediction errors. Lastly, the local MLR models were applied to the data of the respective other field to evaluate the cross-field prediction ability. The spatial SOC pattern generally remains unaffected on both fields; differences, however, occur concerning the predicted SOC level. Our results indicate a high potential of the combination of UAS-based remote sensing and environmental covariates, such as terrain attributes, for the prediction of topsoil SOC content at the field scale. The temporal flexibility of UAS offer the opportunity to optimize flight conditions including weather and soil surface status (plant cover or residuals, moisture and roughness) which, otherwise, might obscure the relationship between spectral data and SOC content. Pedologically targeted selection of soil samples for model development appears to be the key for an efficient and effective prediction even with a small dataset.}, language = {en} } @article{SpikesRodriguezSilvaBennettetal.2021, author = {Spikes, Montrai and Rodr{\´i}guez-Silva, Rodet and Bennett, Kerri-Ann and Br{\"a}ger, Stefan and Josaphat, James and Torres-Pineda, Patricia and Ernst, Anja and Havenstein, Katja and Schlupp, Ingo and Tiedemann, Ralph}, title = {A phylogeny of the genus Limia (Teleostei: Poeciliidae) suggests a single-lake radiation nested in a Caribbean-wide allopatric speciation scenario}, series = {BMC Research Notes}, volume = {14}, journal = {BMC Research Notes}, publisher = {BMC Research Notes / Biomed Central}, address = {London}, issn = {1756-0500}, doi = {10.1186/s13104-021-05843-x}, pages = {1 -- 8}, year = {2021}, abstract = {Objective The Caribbean is an important global biodiversity hotspot. Adaptive radiations there lead to many speciation events within a limited period and hence are particularly prominent biodiversity generators. A prime example are freshwater fish of the genus Limia, endemic to the Greater Antilles. Within Hispaniola, nine species have been described from a single isolated site, Lake Mirago{\^a}ne, pointing towards extraordinary sympatric speciation. This study examines the evolutionary history of the Limia species in Lake Mirago{\^a}ne, relative to their congeners throughout the Caribbean. Results For 12 Limia species, we obtained almost complete sequences of the mitochondrial cytochrome b gene, a well-established marker for lower-level taxonomic relationships. We included sequences of six further Limia species from GenBank (total N  = 18 species). Our phylogenies are in concordance with other published phylogenies of Limia. There is strong support that the species found in Lake Mirago{\^a}ne in Haiti are monophyletic, confirming a recent local radiation. Within Lake Mirago{\^a}ne, speciation is likely extremely recent, leading to incomplete lineage sorting in the mtDNA. Future studies using multiple unlinked genetic markers are needed to disentangle the relationships within the Lake Mirago{\^a}ne clade.}, language = {en} } @article{WarschburgerPetersenvonRezorietal.2021, author = {Warschburger, Petra and Petersen, Ann-Christin and von Rezori, Roman Enzio and Buchallik, Friederike and Baumeister, Harald and Holl, Reinhard and Minden, Kirsten and M{\"u}ller-​Stierlin, Annabel Sandra and Reinauer, Christina and Staab, Doris and COACH consortium,}, title = {A prospective investigation of developmental trajectories of psychosocial adjustment in adolescents facing a chronic condition - study protocol of an observational, multi-center study}, series = {BMC Pediatrics}, volume = {21}, journal = {BMC Pediatrics}, publisher = {BMC pediatrics}, address = {London}, issn = {1471-2431}, doi = {10.1186/s12887-021-02869-9}, pages = {1 -- 13}, year = {2021}, abstract = {Background Relatively little is known about protective factors and the emergence and maintenance of positive outcomes in the field of adolescents with chronic conditions. Therefore, the primary aim of the study is to acquire a deeper understanding of the dynamic process of resilience factors, coping strategies and psychosocial adjustment of adolescents living with chronic conditions. Methods/design We plan to consecutively recruit N = 450 adolescents (12-21 years) from three German patient registries for chronic conditions (type 1 diabetes, cystic fibrosis, or juvenile idiopathic arthritis). Based on screening for anxiety and depression, adolescents are assigned to two parallel groups - "inconspicuous" (PHQ-9 and GAD-7 < 7) vs. "conspicuous" (PHQ-9 or GAD-7 ≥ 7) - participating in a prospective online survey at baseline and 12-month follow-up. At two time points (T1, T2), we assess (1) intra- and interpersonal resiliency factors, (2) coping strategies, and (3) health-related quality of life, well-being, satisfaction with life, anxiety and depression. Using a cross-lagged panel design, we will examine the bidirectional longitudinal relations between resiliency factors and coping strategies, psychological adaptation, and psychosocial adjustment. To monitor Covid-19 pandemic effects, participants are also invited to take part in an intermediate online survey. Discussion The study will provide a deeper understanding of adaptive, potentially modifiable processes and will therefore help to develop novel, tailored interventions supporting a positive adaptation in youths with a chronic condition. These strategies should not only support those at risk but also promote the maintenance of a successful adaptation. Trial registration German Clinical Trials Register (DRKS), no. DRKS00025125. Registered on May 17, 2021.}, language = {en} } @article{Schmidt2021, author = {Schmidt, Imanuel Clemens}, title = {A Secular Tradition}, series = {PaRDeS : Journal of the Association for Jewish Studies in Germany}, journal = {PaRDeS : Journal of the Association for Jewish Studies in Germany}, number = {27}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-520-0}, issn = {1614-6492}, doi = {10.25932/publishup-53286}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-532868}, pages = {85 -- 100}, year = {2021}, abstract = {This article focuses on the social philosopher Horace Kallen and the revisions he made to the concept of cultural pluralism that he first developed in the early 20th century, applying it to postwar America and the young State of Israel. It shows how he opposed the assumption that the United States' social order was based on a "Judeo-Christian tradition." By constructing pluralism as a civil religion and carving out space for secular self-understandings in midcentury America, Kallen attempted to preserve the integrity of his earlier political visions, developed during World War I, of pluralist societies in the United States and Palestine within an internationalist global order. While his perspective on the State of Israel was largely shaped by his American experiences, he revised his approach to politically functionalizing religious traditions as he tested his American understanding of a secular, pluralist society against the political theology effective in the State of Israel. The trajectory of Kallen's thought points to fundamental questions about the compatibility of American and Israeli understandings of religion's function in society and its relation to political belonging, especially in light of their transnational connection through American Jewish support for the recently established state.}, language = {en} } @article{MummHermanussen2021, author = {Mumm, Rebekka and Hermanussen, Michael}, title = {A short note on the BMI and on secular changes in BMI}, series = {Human biology and public health}, journal = {Human biology and public health}, number = {2}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {2748-9957}, doi = {10.52905/hbph.v2.17}, year = {2021}, abstract = {Human size changes over time with worldwide secular trends in height, weight, and body mass index (BMI). There is general agreement to relate the state of nutrition to height and weight, and to ratios of weight-to-height. The BMI is a ratio. It is commonly used to classify underweight, overweight and obesity in adults. Yet, the BMI is inappropriate to provide any immediate information on body composition. It is accepted that the BMI is "a simple index to classify underweight, overweight and obesity in adults". It is stated that "policies, programmes and investments need to be "nutrition-sensitive", which means they must have positive impacts on nutrition". It is also stated that "a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions". But these statements are neither warranted by arithmetic considerations, nor by historic evidence. Measuring the BMI is an appropriate screening tool for detecting an unusual weight-to-height ratio, but the BMI is an inappropriate tool for estimating body composition, or suggesting medical and health policy decisions.}, language = {en} } @article{SchlemmLevermann2021, author = {Schlemm, Tanja and Levermann, Anders}, title = {A simple parametrization of m{\´e}lange buttressing for calving glaciers}, series = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union}, volume = {15}, journal = {The Cryosphere : TC ; an interactive open access journal of the European Geosciences Union}, number = {2}, publisher = {Copernicus}, address = {G{\"o}ttingen}, issn = {1994-0416}, doi = {10.5194/tc-15-531-2021}, pages = {531 -- 545}, year = {2021}, abstract = {Both ice sheets in Greenland and Antarctica are discharging ice into the ocean. In many regions along the coast of the ice sheets, the icebergs calve into a bay. If the addition of icebergs through calving is faster than their transport out of the embayment, the icebergs will be frozen into a melange with surrounding sea ice in winter. In this case, the buttressing effect of the ice melange can be considerably stronger than any buttressing by mere sea ice would be. This in turn stabilizes the glacier terminus and leads to a reduction in calving rates. Here we propose a simple parametrization of ice melange buttressing which leads to an upper bound on calving rates and can be used in numerical and analytical modelling.}, language = {en} } @article{KoertingKoellnerKurasetal.2021, author = {K{\"o}rting, Friederike Magdalena and K{\"o}llner, Nicole and Kuras, Agnieszka and B{\"o}sche, Nina Kristin and Rogass, Christian and Mielke, Christian and Elger, Kirsten and Altenberger, Uwe}, title = {A solar optical hyperspectral library of rare-earth-bearing minerals, rare-earth oxide powders, copper-bearing minerals and Apliki mine surface samples}, series = {Earth system science data : ESSD}, volume = {13}, journal = {Earth system science data : ESSD}, publisher = {Copernics Publications}, address = {Katlenburg-Lindau}, issn = {1866-3508}, doi = {10.5194/essd-13-923-2021}, pages = {923 -- 942}, year = {2021}, abstract = {Mineral resource exploration and mining is an essential part of today's high-tech industry. Elements such as rare-earth elements (REEs) and copper are, therefore, in high demand. Modern exploration techniques from multiple platforms (e.g., spaceborne and airborne), to detect and map the spectral characteristics of the materials of interest, require spectral libraries as an essential reference. They include field and laboratory spectral information in combination with geochemical analyses for validation. Here, we present a collection of REE- and copper-related hyperspectral spectra with associated geochemical information. The libraries contain reflectance spectra from rare-earth element oxides, REE-bearing minerals, copper-bearing minerals and mine surface samples from the Apliki copper-gold-pyrite mine in the Republic of Cyprus. The samples were measured with the HySpex imaging spectrometers in the visible and near infrared (VNIR) and shortwave infrared (SWIR) range (400-2500 nm). The geochemical validation of each sample is provided with the reflectance spectra. The spectral libraries are openly available to assist future mineral mapping campaigns and laboratory spectroscopic analyses. The spectral libraries and corresponding geochemistry are published via GFZ Data Services with the following DOIs: https://doi.org/10.5880/GFZ.1.4.2019.004 (13 REE-bearing minerals and 16 oxide powders, Koerting et al., 2019a), https://doi.org/10.5880/GFZ.1.4.2019.003 (20 copper-bearing minerals, Koellner et al., 2019), and https://doi.org/10.5880/GFZ.1.4.2019.005 (37 copper-bearing surface material samples from the Apliki coppergold-pyrite mine in Cyprus, Koerting et al., 2019b). All spectral libraries are united and comparable by the internally consistent method of hyperspectral data acquisition in the laboratory.}, language = {en} } @article{KuekenWenderingLangaryetal.2021, author = {K{\"u}ken, Anika and Wendering, Philipp and Langary, Damoun and Nikoloski, Zoran}, title = {A structural property for reduction of biochemical networks}, series = {Scientific reports}, volume = {11}, journal = {Scientific reports}, number = {1}, publisher = {Macmillan Publishers Limited, part of Springer Nature}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-021-96835-1}, pages = {11}, year = {2021}, abstract = {Large-scale biochemical models are of increasing sizes due to the consideration of interacting organisms and tissues. Model reduction approaches that preserve the flux phenotypes can simplify the analysis and predictions of steady-state metabolic phenotypes. However, existing approaches either restrict functionality of reduced models or do not lead to significant decreases in the number of modelled metabolites. Here, we introduce an approach for model reduction based on the structural property of balancing of complexes that preserves the steady-state fluxes supported by the network and can be efficiently determined at genome scale. Using two large-scale mass-action kinetic models of Escherichia coli, we show that our approach results in a substantial reduction of 99\% of metabolites. Applications to genome-scale metabolic models across kingdoms of life result in up to 55\% and 85\% reduction in the number of metabolites when arbitrary and mass-action kinetics is assumed, respectively. We also show that predictions of the specific growth rate from the reduced models match those based on the original models. Since steady-state flux phenotypes from the original model are preserved in the reduced, the approach paves the way for analysing other metabolic phenotypes in large-scale biochemical networks.}, language = {en} } @article{RodriguezZuluagaStolleYamazakietal.2021, author = {Rodr{\´i}guez Zuluaga, Juan and Stolle, Claudia and Yamazaki, Yosuke and Xiong, Chao and England, Scott L.}, title = {A synoptic-scale wavelike structure in the nighttime equatorial ionization anomaly}, series = {Earth and Space Science : ESS}, volume = {8}, journal = {Earth and Space Science : ESS}, number = {2}, publisher = {American Geophysical Union}, address = {Malden, Mass.}, issn = {2333-5084}, doi = {10.1029/2020EA001529}, pages = {10}, year = {2021}, abstract = {Both ground- and satellite-based airglow imaging have significantly contributed to understanding the low-latitude ionosphere, especially the morphology and dynamics of the equatorial ionization anomaly (EIA). The NASA Global-scale Observations of the Limb and Disk (GOLD) mission focuses on far-ultraviolet airglow images from a geostationary orbit at 47.5 degrees W. This region is of particular interest at low magnetic latitudes because of the high magnetic declination (i.e., about -20 degrees) and proximity of the South Atlantic magnetic anomaly. In this study, we characterize an exciting feature of the nighttime EIA using GOLD observations from October 5, 2018 to June 30, 2020. It consists of a wavelike structure of a few thousand kilometers seen as poleward and equatorward displacements of the EIA-crests. Initial analyses show that the synoptic-scale structure is symmetric about the dip equator and appears nearly stationary with time over the night. In quasi-dipole coordinates, maxima poleward displacements of the EIA-crests are seen at about +/- 12 degrees latitude and around 20 and 60 degrees longitude (i.e., in geographic longitude at the dip equator, about 53 degrees W and 14 degrees W). The wavelike structure presents typical zonal wavelengths of about 6.7 x 10(3) km and 3.3 x 10(3) km. The structure's occurrence and wavelength are highly variable on a day-to-day basis with no apparent dependence on geomagnetic activity. In addition, a cluster or quasi-periodic wave train of equatorial plasma depletions (EPDs) is often detected within the synoptic-scale structure. We further outline the difference in observing these EPDs from FUV images and in situ measurements during a GOLD and Swarm mission conjunction.}, language = {en} } @article{PrillWalterKrolikowskaetal.2021, author = {Prill, Robert and Walter, Marina and Kr{\´o}likowska, Aleksandra and Becker, Roland}, title = {A systematic review of diagnostic accuracy and clinical applications of wearable movement sensors for knee joint rehabilitation}, series = {Sensors}, volume = {21}, journal = {Sensors}, number = {24}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s21248221}, pages = {14}, year = {2021}, abstract = {In clinical practice, only a few reliable measurement instruments are available for monitoring knee joint rehabilitation. Advances to replace motion capturing with sensor data measurement have been made in the last years. Thus, a systematic review of the literature was performed, focusing on the implementation, diagnostic accuracy, and facilitators and barriers of integrating wearable sensor technology in clinical practices based on a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. For critical appraisal, the COSMIN Risk of Bias tool for reliability and measurement of error was used. PUBMED, Prospero, Cochrane database, and EMBASE were searched for eligible studies. Six studies reporting reliability aspects in using wearable sensor technology at any point after knee surgery in humans were included. All studies reported excellent results with high reliability coefficients, high limits of agreement, or a few detectable errors. They used different or partly inappropriate methods for estimating reliability or missed reporting essential information. Therefore, a moderate risk of bias must be considered. Further quality criterion studies in clinical settings are needed to synthesize the evidence for providing transparent recommendations for the clinical use of wearable movement sensors in knee joint rehabilitation.}, language = {en} } @article{KabothBahrBahrZeedenetal.2021, author = {Kaboth-Bahr, Stefanie and Bahr, Andr{\´e} and Zeeden, Christian and Yamoah, Kweku A. and Lone, Mahjoor Ahmad and Chuang, Chih-Kai and L{\"o}wemark, Ludvig and Wei, Kuo-Yen}, title = {A tale of shifting relations}, series = {Scientific Reports}, volume = {11}, journal = {Scientific Reports}, publisher = {Macmillan Publishers Limited, part of Springer Nature}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-021-85444-7}, pages = {10}, year = {2021}, abstract = {Understanding the dynamics between the East Asian summer (EASM) and winter monsoon (EAWM) is needed to predict their variability under future global warming scenarios. Here, we investigate the relationship between EASM and EAWM as well as the mechanisms driving their variability during the last 10,000 years by stacking marine and terrestrial (non-speleothem) proxy records from the East Asian realm. This provides a regional and proxy independent signal for both monsoonal systems. The respective signal was subsequently analysed using a linear regression model. We find that the phase relationship between EASM and EAWM is not time-constant and significantly depends on orbital configuration changes. In addition, changes in the Atlantic Meridional Overturning circulation, Arctic sea-ice coverage, El Ni{\~n}o-Southern Oscillation and Sun Spot numbers contributed to millennial scale changes in the EASM and EAWM during the Holocene. We also argue that the bulk signal of monsoonal activity captured by the stacked non-speleothem proxy records supports the previously argued bias of speleothem climatic archives to moisture source changes and/or seasonality.}, language = {en} } @article{DoeringGrigorievTapioetal.2021, author = {Doering, Ulrike and Grigoriev, Dmitry and Tapio, Kosti and Rosencrantz, Sophia and Rosencrantz, Ruben R. and Bald, Ilko and B{\"o}ker, Alexander}, title = {About the mechanism of ultrasonically induced protein capsule formation}, series = {RSC Advances : an international journal to further the chemical sciences / Royal Society of Chemistry}, volume = {11}, journal = {RSC Advances : an international journal to further the chemical sciences / Royal Society of Chemistry}, number = {27}, publisher = {RSC Publishing}, address = {London}, issn = {2046-2069}, doi = {10.1039/d0ra08100k}, pages = {16152 -- 16157}, year = {2021}, abstract = {In this paper, we propose a consistent mechanism of protein microcapsule formation upon ultrasound treatment. Aqueous suspensions of bovine serum albumin (BSA) microcapsules filled with toluene are prepared by use of high-intensity ultrasound following a reported method. Stabilization of the oil-in-water emulsion by the adsorption of the protein molecules at the interface of the emulsion droplets is accompanied by the creation of the cross-linked capsule shell due to formation of intermolecular disulfide bonds caused by highly reactive species like superoxide radicals generated sonochemically. The evidence for this mechanism, which until now remained elusive and was not proven properly, is presented based on experimental data from SDS-PAGE, Raman spectroscopy and dynamic light scattering.}, language = {en} } @article{Kulawiak2021, author = {Kulawiak, Pawel R.}, title = {Academic benefits of wearing noise-cancelling headphones during class for typically developing students and students with special needs}, series = {Cogent education}, volume = {8}, journal = {Cogent education}, number = {1}, publisher = {Taylor \& Francis}, address = {Abingdon}, issn = {2331-186X}, doi = {10.1080/2331186X.2021.1957530}, pages = {21}, year = {2021}, abstract = {Classroom noise impairs students' cognition and learning. At a first glance, it seems useful to prevent the negative effects of noise on academic learning by wearing noise-cancelling (NC) headphones during class. The literature and guidelines emphasize the academic benefits of wearing NC headphones (decreased auditory distraction, increased concentration, learning improvement, and decreased distress). These benefits are particularly expected for students with special needs. None of the recommendations to wear NC headphones during class refer to any empirical studies, indicating a potential research gap and lack of evidence. Therefore, the question arises: Is there any empirical evidence supporting academic benefits of wearing NC headphones during class for typically developing students or students with special needs? A total of 13 empirical studies (quantitative and qualitative) were identified through a systematic scoping review of the existing literature. A wide range of outcomes (cognition, learning, academic performance, behaviour, and emotions) were reported related to the use of NC headphones. Most of the studies refer to specific groups of students with special needs (learning disabilities, autism, ADHD, etc.). In view of the limited number of studies, small sample sizes, and lack of replication studies, all studies give the impression of being pilot studies on the academic benefits of wearing NC headphones. The practice of wearing NC headphones during class is an understudied topic. The current body of evidence does not meet the standards for evidence-based practices in both general and special education. Implications for educational practice and future research are discussed.}, language = {en} } @article{HammamiChaabeneKharratetal.2021, author = {Hammami, Raouf and Chaabene, Helmi and Kharrat, Fatma and Werfelli, Hanen and Duncan, Michael and Rebai, Haithem and Granacher, Urs}, title = {Acute effects of different balance exercise types on selected measures of physical fitness in youth female volleyball players}, series = {BMC Sports Science, Medicine and Rehabilitation}, volume = {13}, journal = {BMC Sports Science, Medicine and Rehabilitation}, publisher = {BioMed Central}, address = {London}, issn = {1758-2555}, doi = {10.1186/s13102-021-00249-5}, pages = {8}, year = {2021}, abstract = {Background Earlier studies have shown that balance training (BT) has the potential to induce performance enhancements in selected components of physical fitness (i.e., balance, muscle strength, power, speed). While there is ample evidence on the long-term effects of BT on components of physical fitness in youth, less is known on the short-term or acute effects of single BT sessions on selected measures of physical fitness. Objective To examine the acute effects of different balance exercise types on balance, change-of-direction (CoD) speed, and jump performance in youth female volleyball players. Methods Eleven female players aged 14 years participated in this study. Three types of balance exercises (i.e., anterior, posterolateral, rotational type) were conducted in randomized order. For each exercise, 3 sets including 5 repetitions were performed. Before and after the performance of the balance exercises, participants were tested for their static balance (center of pressure surface area [CoP SA] and velocity [CoP V]) on foam and firm surfaces, CoD speed (T-Half test), and vertical jump height (countermovement jump [CMJ] height). A 3 (condition: anterior, mediolateral, rotational balance exercise type) × 2 (time: pre, post) analysis of variance was computed with repeated measures on time. Results Findings showed no significant condition × time interactions for all outcome measures (p > 0.05). However, there were small main effects of time for CoP SA on firm and foam surfaces (both d = 0.38; all p < 0.05) with no effect for CoP V on both surface conditions (p > 0.05). For CoD speed, findings showed a large main effect of time (d = 0.91; p < 0.001). However, for CMJ height, no main effect of time was observed (p > 0.05). Conclusions Overall, our results indicated small-to-large changes in balance and CoD speed performances but not in CMJ height in youth female volleyball players, regardless of the balance exercise type. Accordingly, it is recommended to regularly integrate balance exercises before the performance of sport-specific training to optimize performance development in youth female volleyball players.}, language = {en} } @article{WerfelliHammamiSelmietal.2021, author = {Werfelli, Hanen and Hammami, Raouf and Selmi, Mohamed Amine and Selmi, Walid and Gabrilo, Goran and Clark, Cain C. T. and Duncan, Michael and Sekulic, Damir and Granacher, Urs and Rebai, Haithem}, title = {Acute Effects of Different Plyometric and Strength Exercises on Balance Performance in Youth Weightlifters}, series = {Frontiers in Physiology}, volume = {12}, journal = {Frontiers in Physiology}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-042X}, doi = {10.3389/fphys.2021.716981}, pages = {9}, year = {2021}, abstract = {Background: High-intensity muscle actions have the potential to temporarily improve the performance which has been denoted as postactivation performance enhancement. Objectives: This study determined the acute effects of different stretch-shortening (fast vs. low) and strength (dynamic vs. isometric) exercises executed during one training session on subsequent balance performance in youth weightlifters. Materials and Methods: Sixteen male and female young weightlifters, aged 11.3±0.6years, performed four strength exercise conditions in randomized order, including dynamic strength (DYN; 3 sets of 3 repetitions of 10 RM) and isometric strength exercises (ISOM; 3 sets of maintaining 3s of 10 RM of back-squat), as well as fast (FSSC; 3 sets of 3 repetitions of 20-cm drop-jumps) and slow (SSSC; 3 sets of 3 hurdle jumps over a 20-cm obstacle) stretch-shortening cycle protocols. Balance performance was tested before and after each of the four exercise conditions in bipedal stance on an unstable surface (i.e., BOSU ball with flat side facing up) using two dependent variables, i.e., center of pressure surface area (CoP SA) and velocity (CoP V). Results: There was a significant effect of time on CoP SA and CoP V [F(1,60)=54.37, d=1.88, p<0.0001; F(1,60)=9.07, d=0.77, p=0.003]. In addition, a statistically significant effect of condition on CoP SA and CoP V [F(3,60)=11.81, d=1.53, p<0.0001; F(3,60)=7.36, d=1.21, p=0.0003] was observed. Statistically significant condition-by-time interactions were found for the balance parameters CoP SA (p<0.003, d=0.54) and CoP V (p<0.002, d=0.70). Specific to contrast analysis, all specified hypotheses were tested and demonstrated that FSSC yielded significantly greater improvements than all other conditions in CoP SA and CoP V [p<0.0001 (d=1.55); p=0.0004 (d=1.19), respectively]. In addition, FSSC yielded significantly greater improvements compared with the two conditions for both balance parameters [p<0.0001 (d=2.03); p<0.0001 (d=1.45)]. Conclusion: Fast stretch-shortening cycle exercises appear to be more effective to improve short-term balance performance in young weightlifters. Due to the importance of balance for overall competitive achievement in weightlifting, it is recommended that young weightlifters implement dynamic plyometric exercises in the fast stretch-shortening cycle during the warm-up to improve their balance performance.}, language = {en} } @article{DellepianeVaidJaladankietal.2021, author = {Dellepiane, Sergio and Vaid, Akhil and Jaladanki, Suraj K. and Coca, Steven and Fayad, Zahi A. and Charney, Alexander W. and B{\"o}ttinger, Erwin and He, John Cijiang and Glicksberg, Benjamin S. and Chan, Lili and Nadkarni, Girish}, title = {Acute kidney injury in patients hospitalized with COVID-19 in New York City}, series = {Kidney medicine}, volume = {3}, journal = {Kidney medicine}, number = {5}, publisher = {Elsevier}, address = {Amsterdam}, issn = {2590-0595}, doi = {10.1016/j.xkme.2021.06.008}, pages = {877 -- 879}, year = {2021}, language = {en} } @article{RomeroMujalliRochowKahletal.2021, author = {Romero-Mujalli, Daniel and Rochow, Markus and Kahl, Sandra M. and Paraskevopoulou, Sofia and Folkertsma, Remco and Jeltsch, Florian and Tiedemann, Ralph}, title = {Adaptive and nonadaptive plasticity in changing environments: Implications for sexual species with different life history strategies}, series = {Ecology and Evolution}, volume = {11}, journal = {Ecology and Evolution}, number = {11}, publisher = {John Wiley \& Sons, Inc.}, address = {New Jersey}, issn = {2045-7758}, pages = {17}, year = {2021}, abstract = {Populations adapt to novel environmental conditions by genetic changes or phenotypic plasticity. Plastic responses are generally faster and can buffer fitness losses under variable conditions. Plasticity is typically modeled as random noise and linear reaction norms that assume simple one-to- one genotype-phenotype maps and no limits to the phenotypic response. Most studies on plasticity have focused on its effect on population viability. However, it is not clear, whether the advantage of plasticity depends solely on environmental fluctuations or also on the genetic and demographic properties (life histories) of populations. Here we present an individual-based model and study the relative importance of adaptive and nonadaptive plasticity for populations of sexual species with different life histories experiencing directional stochastic climate change. Environmental fluctuations were simulated using differentially autocorrelated climatic stochasticity or noise color, and scenarios of directiona climate change. Nonadaptive plasticity was simulated as a random environmental effect on trait development, while adaptive plasticity as a linear, saturating, or sinusoidal reaction norm. The last two imposed limits to the plastic response and emphasized flexible interactions of the genotype with the environment. Interestingly, this assumption led to (a) smaller phenotypic than genotypic variance in the population (many-to- one genotype-phenotype map) and the coexistence of polymorphisms, and (b) the maintenance of higher genetic variation—compared to linear reaction norms and genetic determinism—even when the population was exposed to a constant environment for several generations. Limits to plasticity led to genetic accommodation, when costs were negligible, and to the appearance of cryptic variation when limits were exceeded. We found that adaptive plasticity promoted population persistence under red environmental noise and was particularly important for life histories with low fecundity. Populations produing more offspring could cope with environmental fluctuations solely by genetic changes or random plasticity, unless environmental change was too fast.}, language = {en} } @article{SchaeferDechBittmann2021, author = {Schaefer, Laura and Dech, Silas and Bittmann, Frank}, title = {Adaptive force and emotionally related imaginations}, series = {Heliyon}, volume = {7}, journal = {Heliyon}, number = {8}, publisher = {Elsevier}, address = {London}, issn = {2405-8440}, doi = {10.1016/j.heliyon.2021.e07827}, pages = {13}, year = {2021}, abstract = {The link between emotions and motor control has been discussed for years. The measurement of the Adaptive Force (AF) provides the possibility to get insights into the adaptive control of the neuromuscular system in reaction to external forces. It was hypothesized that the holding isometric AF is especially vulnerable to disturbing inputs. Here, the behavior of the AF under the influence of positive (tasty) vs. negative (disgusting) food imaginations was investigated. The AF was examined in n = 12 cases using an objectified manual muscle test of the hip flexors, elbow flexors or pectoralis major muscle, performed by one of two experienced testers while the participants imagined their most tasty or most disgusting food. The reaction force and the limb position were measured by a handheld device. While the slope of force rises and the maximal AF did not differ significantly between tasty and disgusting imaginations (p > 0.05), the maximal isometric AF was significantly lower and the AF at the onset of oscillations was significantly higher under disgusting vs. tasty imaginations (both p = 0.001). A proper length tension control of muscles seems to be a crucial functional parameter of the neuromuscular system which can be impaired instantaneously by emotionally related negative imaginations. This might be a potential approach to evaluate somatic reactions to emotions.}, language = {en} } @article{BirukovCuadratPolemitietal.2021, author = {Birukov, Anna and Cuadrat, Rafael R. C. and Polemiti, Elli and Eichelmann, Fabian and Schulze, Matthias Bernd}, title = {Advanced glycation end-products, measured as skin autofluorescence, associate with vascular stiffness in diabetic, pre-diabetic and normoglycemic individuals}, series = {Cardiovascular diabetology}, volume = {20}, journal = {Cardiovascular diabetology}, number = {1}, publisher = {BioMed Central}, address = {London}, issn = {1475-2840}, doi = {10.1186/s12933-021-01296-5}, pages = {11}, year = {2021}, abstract = {Background Advanced glycation end-products are proteins that become glycated after contact with sugars and are implicated in endothelial dysfunction and arterial stiffening. We aimed to investigate the relationships between advanced glycation end-products, measured as skin autofluorescence, and vascular stiffness in various glycemic strata. Methods We performed a cross-sectional analysis within the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam cohort, comprising n = 3535 participants (median age 67 years, 60\% women). Advanced glycation end-products were measured as skin autofluorescence with AGE-Reader (TM), vascular stiffness was measured as pulse wave velocity, augmentation index and ankle-brachial index with Vascular Explorer (TM). A subset of 1348 participants underwent an oral glucose tolerance test. Participants were sub-phenotyped into normoglycemic, prediabetes and diabetes groups. Associations between skin autofluorescence and various indices of vascular stiffness were assessed by multivariable regression analyses and were adjusted for age, sex, measures of adiposity and lifestyle, blood pressure, prevalent conditions, medication use and blood biomarkers. Results Skin autofluorescence associated with pulse wave velocity, augmentation index and ankle-brachial index, adjusted beta coefficients (95\% CI) per unit skin autofluorescence increase: 0.38 (0.21; 0.55) for carotid-femoral pulse wave velocity, 0.25 (0.14; 0.37) for aortic pulse wave velocity, 1.00 (0.29; 1.70) for aortic augmentation index, 4.12 (2.24; 6.00) for brachial augmentation index and - 0.04 (- 0.05; - 0.02) for ankle-brachial index. The associations were strongest in men, younger individuals and were consistent across all glycemic strata: for carotid-femoral pulse wave velocity 0.36 (0.12; 0.60) in normoglycemic, 0.33 (- 0.01; 0.67) in prediabetes and 0.45 (0.09; 0.80) in diabetes groups; with similar estimates for aortic pulse wave velocity. Augmentation index was associated with skin autofluorescence only in normoglycemic and diabetes groups. Ankle-brachial index inversely associated with skin autofluorescence across all sex, age and glycemic strata. Conclusions Our findings indicate that advanced glycation end-products measured as skin autofluorescence might be involved in vascular stiffening independent of age and other cardiometabolic risk factors not only in individuals with diabetes but also in normoglycemic and prediabetic conditions. Skin autofluorescence might prove as a rapid and non-invasive method for assessment of macrovascular disease progression across all glycemic strata.}, language = {en} } @misc{RobinKatharinaEmilyetal.2021, author = {Robin, Koger and Katharina, Syb{\"o}ck and Emily, Weinelt and Beda, Hartmann and Kirchengast, Sylvia}, title = {Advanced maternal age and nicotine consumption during pregnancy}, series = {Human Biology and Public Health}, volume = {2021}, journal = {Human Biology and Public Health}, number = {1}, editor = {Scheffler, Christiane and Koziel, Slawomir and Hermanussen, Michael and Bogin, Barry}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {2748-9957}, doi = {10.52905/hbph.v1.6}, pages = {1 -- 19}, year = {2021}, abstract = {Background Nicotine consumption during pregnancy and advanced maternal age are well known independent risk factors for poor pregnancy outcome and therefore serious public health problems. Objectives Considering the ongoing trend of delaying childbirth in our society, this study investigates potential additive effects of nicotine consumption during pregnancy and advanced maternal age on foetal growth. Sample and Methods In a medical record-based study, we analysed the impact of maternal age and smoking behaviour before and during pregnancy on newborn size among 4142 singleton births that took place in Vienna, Austria between 1990 and 1995. Results Birth weight (H=82.176, p<0.001), birth length (H=91.525, p<0.001) and head circumference (H=42.097, p<0.001) differed significantly according to maternal smoking behaviour. For birth weight, the adjusted mean differences between smokers and non-smokers increased from 101.8g for the < 18-year-old mothers to 254.8g for >35 year olds, with the respective values for birth length being 0.6 cm to 0.7cm, for head circumference from 0.3 cm to 0.6 cm. Conclusion Increasing maternal age amplified the negative effects of smoking during pregnancy on newborn parameters. Our findings identify older smoking mothers as a high-risk group which should be of special interest for public health systems.}, language = {en} } @article{FuehnerGranacherGolleetal.2021, author = {F{\"u}hner, Thea Heidi and Granacher, Urs and Golle, Kathleen and Kliegl, Reinhold}, title = {Age and sex effects in physical fitness components of 108,295 third graders including 515 primary schools and 9 cohorts}, series = {Scientific Reports}, volume = {11}, journal = {Scientific Reports}, publisher = {Nature Portfolio}, address = {Berlin}, issn = {2045-2322}, doi = {10.1038/s41598-021-97000-4}, pages = {1 -- 13}, year = {2021}, abstract = {Children's physical fitness development and related moderating effects of age and sex are well documented, especially boys' and girls' divergence during puberty. The situation might be different during prepuberty. As girls mature approximately two years earlier than boys, we tested a possible convergence of performance with five tests representing four components of physical fitness in a large sample of 108,295 eight-year old third-graders. Within this single prepubertal year of life and irrespective of the test, performance increased linearly with chronological age, and boys outperformed girls to a larger extent in tests requiring muscle mass for successful performance. Tests differed in the magnitude of age effects (gains), but there was no evidence for an interaction between age and sex. Moreover, "physical fitness" of schools correlated at r = 0.48 with their age effect which might imply that "fit schools" promote larger gains; expected secular trends from 2011 to 2019 were replicated.}, language = {en} } @article{SchlomannBuenningHippetal.2021, author = {Schlomann, Anna and B{\"u}nning, Mareike and Hipp, Lena and Wahl, Hans-Werner}, title = {Aging during COVID-19 in Germany}, series = {European journal of ageing : social, behavioural and health perspectives}, volume = {19}, journal = {European journal of ageing : social, behavioural and health perspectives}, number = {4}, publisher = {Springer}, address = {Berlin}, issn = {1613-9372}, doi = {10.1007/s10433-021-00655-1}, pages = {1077 -- 1086}, year = {2021}, abstract = {Existing theories of aging suggest that there may be similarities and differences in how COVID-19 impacts older people's psychosocial adaptation compared to younger age groups, particularly middle-aged individuals. To assess the degree to which these impacts vary, we analyzed data from 3098 participants between the ages of 40 and 79 from an online survey in Germany. Data were collected at three measurement occasions between the start of the nationwide lockdown in mid-March 2020 and the end of the lockdown in early August 2020. The survey focused on everyday experiences during the COVID-19 crisis and collected various satisfaction ratings (e.g., general life satisfaction, satisfaction with family life, satisfaction with social contacts). At baseline, participants also provided retrospective ratings of satisfaction for the period before the COVID-19 crisis. In our analyses, we compared satisfaction ratings of middle-aged (40-64 years) and older individuals (65-79 years) and found that both middle-aged and older participants experienced the greatest decreases in satisfaction with social contacts, with more pronounced decreases seen in middle-aged participants. A similar pattern was observed for general life satisfaction, but the overall decreases were less pronounced in both groups compared to the decreases in satisfaction with social contacts. We also observed a partial recovery effect in all measures at the last measurement occasion, and this effect was more pronounced in older adults. Findings were also confirmed using age as a continuous variable and checking for linear and nonlinear effects of outcomes across the age range. Although ageism arose during the pandemic in the sense that older adults were labeled as a "risk group," particularly at the start of the outbreak, we found consistently with other studies that middle-aged adults' satisfaction decreased to a greater extent than that of older adults.}, language = {en} } @misc{Sternagel2021, author = {Sternagel, Renate}, title = {Alexander von Humboldt, Therese von Bacheracht, und die „verh{\"a}ngnissvolle Prosa des Lebens"}, series = {HiN : Alexander von Humboldt im Netz}, volume = {XXII}, journal = {HiN : Alexander von Humboldt im Netz}, number = {43}, editor = {Ette, Ottmar and Knobloch, Eberhard}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {2568-3543}, doi = {10.25932/publishup-53328}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-533283}, pages = {83 -- 100}, year = {2021}, abstract = {Ausgehend von einem Brief Alexander von Humboldts an die Schriftstellerin Therese von Bacheracht(1804 - 1852) wird die Geschichte der Herausgabe der Briefe seines Bruders Wilhelm an Charlotte Diede im Jahr 1847, nach dem Tod beider Korrespondenten, nachgezeichnet. Besonders wird dabei auf die bisher unver{\"o}ffentlichten „Tagesbl{\"a}tter" Karl August Varnhagens von Ense zur{\"u}ckgegriffen, aus denen hervorgeht, dass Alexander von Humboldt seine anfangs ablehnende Haltung aufgibt, Varnhagen mit der Pr{\"u}fung und Korrektur des Manuskripts betraut, und dass Therese von Bacheracht durch Hartn{\"a}ckigkeit und Charme ihr Ziel erreicht, die nicht unbetr{\"a}chtlichen Einnahmen aus der Ver{\"o}ffentlichung zugesprochen zu bekommen.}, language = {de} } @article{LeBrunRicalensLujanWey2021, author = {Le Brun-Ricalens, Foni and Luj{\´a}n, Leonardo L{\´o}pez and Wey, Claude}, title = {Alexander von Humboldts „Aztekische Priesterin" alias die Chalchiuhtlicue aus der Sammlung Guillermo Dupaix. Historiografi scher Essay einer Translokation von Mexico-Stadt nach London}, series = {HiN : Alexander von Humboldt im Netz}, volume = {XXII}, journal = {HiN : Alexander von Humboldt im Netz}, number = {43}, editor = {Ette, Ottmar and Knobloch, Eberhard}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {2568-3543}, doi = {10.25932/publishup-53280}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-532802}, pages = {13 -- 28}, year = {2021}, abstract = {W{\"a}hrend seines Aufenthalts 1803 in Mexiko machte von Humboldt die Bekanntschaft von Dupaix, einem spanischen Soldaten luxemburgischer Herkunft und Liebhaber pr{\"a}kolumbischer Altert{\"u}mer. Die Entdeckung verschiedener Manuskripte Dupaix' sowie die Untersuchung diverser Archive und pers{\"o}nlicher Aufzeichnungen des Freiherrn und von Dokumenten unterschiedlicher Institutionen beiderseits des Atlantiks erlauben es, den außergew{\"o}hnlichen Weg eines ber{\"u}hmten mexikanischen Objekts, der Chalchiuhtlicue, nachzuvollziehen, die der preußische Forschungsreisende 1810 als „aztekische Priesterin" in seinem Buch Vues des cordill{\`e}res … beschrieben hatte. Der vorliegende Beitrag versucht, die verschiedenen Besitzer und die Umst{\"a}nde nachzuzeichnen, welche die Wanderung dieser emblematischen pr{\"a}hispanischen Statuette von Mexiko-Stadt nach London fast ein halbes Jahrhundert lang begleitet haben.}, language = {de} } @article{WarszawskiKrieglerLentonetal.2021, author = {Warszawski, Lila and Kriegler, Elmar and Lenton, Timothy M. and Gaffney, Owen and Jacob, Daniela and Klingenfeld, Daniel and Koide, Ryu and Costa, Mar{\´i}a M{\´a}{\~n}ez and Messner, Dirk and Nakicenovic, Nebojsa and Schellnhuber, Hans Joachim and Schlosser, Peter and Takeuchi, Kazuhiko and van der Leeuw, Sander and Whiteman, Gail and Rockstr{\"o}m, Johan}, title = {All options, not silver bullets, needed to limit global warming to 1.5 °C}, series = {Environmental research letters}, volume = {16}, journal = {Environmental research letters}, number = {6}, publisher = {IOP Publishing}, address = {Bristol}, issn = {1748-9326}, doi = {10.1088/1748-9326/abfeec}, pages = {15}, year = {2021}, abstract = {Climate science provides strong evidence of the necessity of limiting global warming to 1.5 °C, in line with the Paris Climate Agreement. The IPCC 1.5 °C special report (SR1.5) presents 414 emissions scenarios modelled for the report, of which around 50 are classified as '1.5 °C scenarios', with no or low temperature overshoot. These emission scenarios differ in their reliance on individual mitigation levers, including reduction of global energy demand, decarbonisation of energy production, development of land-management systems, and the pace and scale of deploying carbon dioxide removal (CDR) technologies. The reliance of 1.5 °C scenarios on these levers needs to be critically assessed in light of the potentials of the relevant technologies and roll-out plans. We use a set of five parameters to bundle and characterise the mitigation levers employed in the SR1.5 1.5 °C scenarios. For each of these levers, we draw on the literature to define 'medium' and 'high' upper bounds that delineate between their 'reasonable', 'challenging' and 'speculative' use by mid century. We do not find any 1.5 °C scenarios that stay within all medium upper bounds on the five mitigation levers. Scenarios most frequently 'over use' CDR with geological storage as a mitigation lever, whilst reductions of energy demand and carbon intensity of energy production are 'over used' less frequently. If we allow mitigation levers to be employed up to our high upper bounds, we are left with 22 of the SR1.5 1.5 °C scenarios with no or low overshoot. The scenarios that fulfil these criteria are characterised by greater coverage of the available mitigation levers than those scenarios that exceed at least one of the high upper bounds. When excluding the two scenarios that exceed the SR1.5 carbon budget for limiting global warming to 1.5 °C, this subset of 1.5 °C scenarios shows a range of 15-22 Gt CO2 (16-22 Gt CO2 interquartile range) for emissions in 2030. For the year of reaching net zero CO2 emissions the range is 2039-2061 (2049-2057 interquartile range).}, language = {en} } @article{MachlebSeyboth2021, author = {Machleb, Franziska and Seyboth, Margret}, title = {Alles kann besser werden!}, series = {Spektrum Patholinguistik}, journal = {Spektrum Patholinguistik}, number = {14}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-507-1}, issn = {1866-9085}, doi = {10.25932/publishup-51041}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-510412}, pages = {121 -- 137}, year = {2021}, language = {de} } @article{BuschBlasimannMayeretal.2021, author = {Busch, Aglaja and Blasimann, Angela and Mayer, Frank and Baur, Heiner}, title = {Alterations in sensorimotor function after ACL reconstruction during active joint position sense testing. A systematic review}, series = {PLOS ONE}, volume = {16}, journal = {PLOS ONE}, number = {6}, publisher = {PLOS}, address = {San Francisco}, issn = {1932-6203}, doi = {10.1371/journal.pone.0253503}, pages = {14}, year = {2021}, abstract = {Background The anterior cruciate ligament (ACL) rupture can lead to impaired knee function. Reconstruction decreases the mechanical instability but might not have an impact on sensorimotor alterations. Objective Evaluation of the sensorimotor function measured with the active joint position sense (JPS) test in anterior cruciate ligament (ACL) reconstructed patients compared to the contralateral side and a healthy control group. Methods The databases MEDLINE, CINAHL, EMBASE, PEDro, Cochrane Library and SPORTDiscus were systematically searched from origin until April 2020. Studies published in English, German, French, Spanish or Italian language were included. Evaluation of the sensorimotor performance was restricted to the active joint position sense test in ACL reconstructed participants or healthy controls. The Preferred Items for Systematic Reviews and Meta-Analyses guidelines were followed. Study quality was evaluated using the Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. Data was descriptively synthesized. Results Ten studies were included after application of the selective criteria. Higher angular deviation, reaching significant difference (p < 0.001) in one study, was shown up to three months after surgery in the affected limb. Six months post-operative significantly less error (p < 0.01) was found in the reconstructed leg compared to the contralateral side and healthy controls. One or more years after ACL reconstruction significant differences were inconsistent along the studies. Conclusions Altered sensorimotor function was present after ACL reconstruction. Due to inconsistencies and small magnitudes, clinical relevance might be questionable. JPS testing can be performed in acute injured persons and prospective studies could enhance knowledge of sensorimotor function throughout the rehabilitative processes.}, language = {en} } @article{StreflerKrieglerBaueretal.2021, author = {Strefler, Jessica and Kriegler, Elmar and Bauer, Nico and Luderer, Gunnar and Pietzcker, Robert C. and Giannousakis, Anastasis and Edenhofer, Ottmar}, title = {Alternative carbon price trajectories can avoid excessive carbon removal}, series = {Nature communications}, volume = {12}, journal = {Nature communications}, number = {1}, publisher = {Nature Publishing Group}, address = {London}, issn = {2041-1723}, doi = {10.1038/s41467-021-22211-2}, pages = {8}, year = {2021}, abstract = {The large majority of climate change mitigation scenarios that hold warming below 2 °C show high deployment of carbon dioxide removal (CDR), resulting in a peak-and-decline behavior in global temperature. This is driven by the assumption of an exponentially increasing carbon price trajectory which is perceived to be economically optimal for meeting a carbon budget. However, this optimality relies on the assumption that a finite carbon budget associated with a temperature target is filled up steadily over time. The availability of net carbon removals invalidates this assumption and therefore a different carbon price trajectory should be chosen. We show how the optimal carbon price path for remaining well below 2 °C limits CDR demand and analyze requirements for constructing alternatives, which may be easier to implement in reality. We show that warming can be held at well below 2 °C at much lower long-term economic effort and lower CDR deployment and therefore lower risks if carbon prices are high enough in the beginning to ensure target compliance, but increase at a lower rate after carbon neutrality has been reached.}, language = {en} } @incollection{LoewSaymanSchwereretal.2021, author = {L{\"o}w, Martina and Sayman, Volkan and Schwerer, Jona and Wolf, Hannah}, title = {Am Ende der Globalisierung}, series = {Am Ende der Globalisierung}, booktitle = {Am Ende der Globalisierung}, editor = {L{\"o}w, Martina and Sayman, Volkan and Schwerer, Jona and Wolf, Hannah}, publisher = {transcript}, address = {Bielefeld}, isbn = {978-3-8394-5402-2}, doi = {10.14361/9783839454022}, pages = {9 -- 22}, year = {2021}, language = {de} } @book{OPUS4-64594, title = {Am Ende der Globalisierung}, series = {Re-Figuration von R{\"a}umen}, volume = {1}, journal = {Re-Figuration von R{\"a}umen}, editor = {L{\"o}w, Martina and Sayman, Volkan and Schwerer, Jona and Wolf, Hannah}, publisher = {transcript}, address = {Bielefeld}, isbn = {978-3-8376-5402-8}, doi = {10.14361/9783839454022}, pages = {481}, year = {2021}, abstract = {Die Globalisierung ist zur allgegenw{\"a}rtigen Gewissheit geworden. Doch wie zutreffend ist das Konzept »Globalisierung«, wenn zeitgleich nationale Grenzen gest{\"a}rkt und transnationale Freihandelszonen ausgeweitet werden, wenn auf unterschiedlichen scales Territorien {\"u}berwunden und zugleich territoriale Abgrenzungen neu gesetzt werden? Aktuelle Ver{\"a}nderungen als Re-Figuration von R{\"a}umen zu verstehen, erm{\"o}glicht die Analyse und Diskussion widerspr{\"u}chlicher, spannungsreicher und konflikthafter r{\"a}umlicher Prozesse und ihrer allt{\"a}glichen Erfahrung. Die interdisziplin{\"a}ren Beitr{\"a}ge des Bandes liefern theoretische und empirische Analysen zu politischen, digitalen und allt{\"a}glichen R{\"a}umen im Konzept der Re-Figuration.}, language = {de} } @article{LangeBuerkner2021, author = {Lange, Bastian and B{\"u}rkner, Hans-Joachim}, title = {Ambiguous avant-gardes and their geographies}, series = {Die Erde : journal of the Geographical Society of Berlin ; Zeitschrift der Gesellschaft f{\"u}r Erdkunde zu Berlin}, volume = {152}, journal = {Die Erde : journal of the Geographical Society of Berlin ; Zeitschrift der Gesellschaft f{\"u}r Erdkunde zu Berlin}, number = {4}, publisher = {Gesellschaft f{\"u}r Erdkunde}, address = {Berlin}, issn = {0013-9998}, doi = {10.12854/erde-2021-566}, pages = {273 -- 287}, year = {2021}, abstract = {In the following article, the focus is on the transformative potentials created by so-called persistence avant-gardes and prevention innovators. The text extends Bluhdorn's guiding concept of narratives of hope (Bluhdorn 2017; Bluhdorn and Butzlaff 2019) by considering those groups that are marginalized within debates on socio-ecological transformation. With a closer look at the narratives of prevention and blockade that these actors engage, the ambiguous nature of postgrowth avant-gardes is carved out. Their discursive, argumentative, and effective inhibition of transitory policies is interpreted as a pro-active potential, rather than a mere obstacle to socio-ecological transformation. Adding a geographical perspective, the paper pleads for a more precise theoretical penetration of the ambivalent figure of avantgardes when analyzing processes of local and regional postgrowth.}, language = {en} } @article{Schwartz2021, author = {Schwartz, Yitzchak}, title = {American Jewish Ideas in a Transnational Jewish World, 1843-1900}, series = {PaRDeS : Journal of the Association for Jewish Studies in Germany}, journal = {PaRDeS : Journal of the Association for Jewish Studies in Germany}, number = {27}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-520-0}, issn = {1614-6492}, doi = {10.25932/publishup-53283}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-532835}, pages = {39 -- 52}, year = {2021}, abstract = {As mid-19th-century American Jews introduced radical changes to their religious observance and began to define Judaism in new ways, to what extent did they engage with European Jewish ideas? Historians often approach religious change among Jews from German lands during this period as if Jewish immigrants had come to America with one set of ideas that then evolved solely in conversation with their American contexts. Historians have similarly cast the kinds of Judaism Americans created as both unique to America and uniquely American. These characterizations are accurate to an extent. But to what extent did Jewish innovations in the United States take place in conversation with European Jewish developments? Looking to the 19th-century American Jewish press, this paper seeks to understand how American Jews engaged European Judaism in formulating their own ideas, understanding themselves, and understanding their place in world Judaism.}, language = {en} } @article{MusculusTuenteRaabetal.2021, author = {Musculus, Lisa and T{\"u}nte, Markus R. and Raab, Markus and Kayhan, Ezgi}, title = {An Embodied Cognition Perspective on the Role of Interoception in the Development of the Minimal Self}, series = {Frontiers in Psychology}, volume = {12}, journal = {Frontiers in Psychology}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-1078}, doi = {10.3389/fpsyg.2021.716950}, pages = {7}, year = {2021}, abstract = {Interoception is an often neglected but crucial aspect of the human minimal self. In this perspective, we extend the embodiment account of interoceptive inference to explain the development of the minimal self in humans. To do so, we first provide a comparative overview of the central accounts addressing the link between interoception and the minimal self. Grounding our arguments on the embodiment framework, we propose a bidirectional relationship between motor and interoceptive states, which jointly contribute to the development of the minimal self. We present empirical findings on interoception in development and discuss the role of interoception in the development of the minimal self. Moreover, we make theoretical predictions that can be tested in future experiments. Our goal is to provide a comprehensive view on the mechanisms underlying the minimal self by explaining the role of interoception in the development of the minimal self.}, language = {en} } @article{JararnezhadgeroMamashliGranacher2021, author = {Jararnezhadgero, AmirAli and Mamashli, Elaheh and Granacher, Urs}, title = {An Endurance-Dominated Exercise Program Improves Maximum Oxygen Consumption, Ground Reaction Forces, and Muscle Activities in Patients With Moderate Diabetic Neuropathy}, series = {Frontiers in physiology / Frontiers Research Foundation}, volume = {12}, journal = {Frontiers in physiology / Frontiers Research Foundation}, publisher = {Frontiers Research Foundation}, address = {Lausanne, Schweiz}, issn = {1664-042X}, doi = {10.3389/fphys.2021.654755}, pages = {1 -- 15}, year = {2021}, abstract = {Background: The prevalence of diabetes worldwide is predicted to increase from 2.8\% in 2000 to 4.4\% in 2030. Diabetic neuropathy (DN) is associated with damage to nerve glial cells, their axons, and endothelial cells leading to impaired function and mobility. Objective: We aimed to examine the effects of an endurance-dominated exercise program on maximum oxygen consumption (VO2max), ground reaction forces, and muscle activities during walking in patients with moderate DN. Methods: Sixty male and female individuals aged 45-65 years with DN were randomly assigned to an intervention (IG, n = 30) or a waiting control (CON, n = 30) group. The research protocol of this study was registered with the Local Clinical Trial Organization (IRCT20200201046326N1). IG conducted an endurance-dominated exercise program including exercises on a bike ergometer and gait therapy. The progressive intervention program lasted 12 weeks with three sessions per week, each 40-55 min. CON received the same treatment as IG after the post-tests. Pre- and post-training, VO2max was tested during a graded exercise test using spiroergometry. In addition, ground reaction forces and lower limbs muscle activities were recorded while walking at a constant speed of ∼1 m/s. Results: No statistically significant baseline between group differences was observed for all analyzed variables. Significant group-by-time interactions were found for VO2max (p < 0.001; d = 1.22). The post-hoc test revealed a significant increase in IG (p < 0.001; d = 1.88) but not CON. Significant group-by-time interactions were observed for peak lateral and vertical ground reaction forces during heel contact and peak vertical ground reaction force during push-off (p = 0.001-0.037; d = 0.56-1.53). For IG, post-hoc analyses showed decreases in peak lateral (p < 0.001; d = 1.33) and vertical (p = 0.004; d = 0.55) ground reaction forces during heel contact and increases in peak vertical ground reaction force during push-off (p < 0.001; d = 0.92). In terms of muscle activity, significant group-by-time interactions were found for vastus lateralis and gluteus medius during the loading phase and for vastus medialis during the mid-stance phase, and gastrocnemius medialis during the push-off phase (p = 0.001-0.044; d = 0.54-0.81). Post-hoc tests indicated significant intervention-related increases in vastus lateralis (p = 0.001; d = 1.08) and gluteus medius (p = 0.008; d = 0.67) during the loading phase and vastus medialis activity during mid-stance (p = 0.001; d = 0.86). In addition, post-hoc tests showed decreases in gastrocnemius medialis during the push-off phase in IG only (p < 0.001; d = 1.28). Conclusions: This study demonstrated that an endurance-dominated exercise program has the potential to improve VO2max and diabetes-related abnormal gait in patients with DN. The observed decreases in peak vertical ground reaction force during the heel contact of walking could be due to increased vastus lateralis and gluteus medius activities during the loading phase. Accordingly, we recommend to implement endurance-dominated exercise programs in type 2 diabetic patients because it is feasible, safe and effective by improving aerobic capacity and gait characteristics.}, language = {en} } @article{NakoudiStachlewskaRitter2021, author = {Nakoudi, Konstantina and Stachlewska, Iwona S. and Ritter, Christoph}, title = {An extended lidar-based cirrus cloud retrieval scheme}, series = {Optics express : the international electronic journal of optics / Optica}, volume = {29}, journal = {Optics express : the international electronic journal of optics / Optica}, number = {6}, publisher = {Optical Society of America}, address = {Washington}, issn = {1094-4087}, doi = {10.1364/OE.414770}, pages = {8553 -- 8580}, year = {2021}, abstract = {Accurate and precise characterization of cirrus cloud geometrical and optical properties is essential for better constraining their radiative footprint. A lidar-based retrieval scheme is proposed here, with its performance assessed on fine spatio-temporal observations over the Arctic site of Ny-Alesund, Svalbard. Two contributions related to cirrus geometrical (dynamic Wavelet Covariance Transform (WCT)) and optical properties (constrained Klett) are reported. The dynamic WCT rendered cirrus detection more robust, especially for thin cirrus layers that frequently remained undetected by the classical WCT method. Regarding optical characterization, we developed an iterative scheme for determining the cirrus lidar ratio (LRci) that is a crucial parameter for aerosol - cloud discrimination. Building upon the Klett-Fernald method, the LRci was constrained by an additional reference value. In established methods, such as the double-ended Klett, an aerosol-free reference value is applied. In the proposed constrained Klett, however, the reference value was approximated from cloud-free or low cloud optical depth (COD up to 0.2) profiles and proved to agree with independent Raman estimates. For optically thin cirrus, the constrained Klett inherent uncertainties reached 50\% (60-74\%) in terms of COD (LRci). However, for opaque cirrus COD (LRci) uncertainties were lower than 10\% (15\%). The detection method discrepancies (dynamic versus static WCT) had a higher impact on the optical properties of low COD layers (up to 90\%) compared to optically thicker ones (less than 10\%). The constrained Klett presented high agreement with two established retrievals. For an exemplary cirrus cloud, the constrained Klett estimated the COD355 (LRci355) at 0.28 +/- 0.17 (29 +/- 4 sr), the double-ended Klett at 0.27 +/- 0.15 (32 +/- 4 sr) and the Raman retrievals at 0.22 +/- 0.12 (26 +/- 11 sr). Our approach to determine the necessary reference value can also be applied in established methods and increase their accuracy. In contrast, the classical aerosol-free assumption led to 44 sr LRci overestimation in optically thin layers and 2-8 sr in thicker ones. The multiple scattering effect was corrected using Eloranta (1998) and accounted for 50-60\% extinction underestimation near the cloud base and 20-30\% within the cirrus layers.}, language = {en} } @book{BaltzerHradilakPfennigschmidtetal.2021, author = {Baltzer, Wanda and Hradilak, Theresa and Pfennigschmidt, Lara and Prestin, Luc Maurice and Spranger, Moritz and Stadlinger, Simon and Wendt, Leo and Lincke, Jens and Rein, Patrick and Church, Luke and Hirschfeld, Robert}, title = {An individual-centered approach to visualize people's opinions and demographic information}, number = {136}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-504-0}, issn = {1613-5652}, doi = {10.25932/publishup-49145}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-491457}, publisher = {Universit{\"a}t Potsdam}, pages = {326}, year = {2021}, abstract = {The noble way to substantiate decisions that affect many people is to ask these people for their opinions. For governments that run whole countries, this means asking all citizens for their views to consider their situations and needs. Organizations such as Africa's Voices Foundation, who want to facilitate communication between decision-makers and citizens of a country, have difficulty mediating between these groups. To enable understanding, statements need to be summarized and visualized. Accomplishing these goals in a way that does justice to the citizens' voices and situations proves challenging. Standard charts do not help this cause as they fail to create empathy for the people behind their graphical abstractions. Furthermore, these charts do not create trust in the data they are representing as there is no way to see or navigate back to the underlying code and the original data. To fulfill these functions, visualizations would highly benefit from interactions to explore the displayed data, which standard charts often only limitedly provide. To help improve the understanding of people's voices, we developed and categorized 80 ideas for new visualizations, new interactions, and better connections between different charts, which we present in this report. From those ideas, we implemented 10 prototypes and two systems that integrate different visualizations. We show that this integration allows consistent appearance and behavior of visualizations. The visualizations all share the same main concept: representing each individual with a single dot. To realize this idea, we discuss technologies that efficiently allow the rendering of a large number of these dots. With these visualizations, direct interactions with representations of individuals are achievable by clicking on them or by dragging a selection around them. This direct interaction is only possible with a bidirectional connection from the visualization to the data it displays. We discuss different strategies for bidirectional mappings and the trade-offs involved. Having unified behavior across visualizations enhances exploration. For our prototypes, that includes grouping, filtering, highlighting, and coloring of dots. Our prototyping work was enabled by the development environment Lively4. We explain which parts of Lively4 facilitated our prototyping process. Finally, we evaluate our approach to domain problems and our developed visualization concepts. Our work provides inspiration and a starting point for visualization development in this domain. Our visualizations can improve communication between citizens and their government and motivate empathetic decisions. Our approach, combining low-level entities to create visualizations, provides value to an explorative and empathetic workflow. We show that the design space for visualizing this kind of data has a lot of potential and that it is possible to combine qualitative and quantitative approaches to data analysis.}, language = {en} } @article{SchindlerMoldenhawerStangeetal.2021, author = {Schindler, Daniel and Moldenhawer, Ted and Stange, Maike and Lepro, Valentino and Beta, Carsten and Holschneider, Matthias and Huisinga, Wilhelm}, title = {Analysis of protrusion dynamics in amoeboid cell motility by means of regularized contour flows}, series = {PLoS Computational Biology : a new community journal}, volume = {17}, journal = {PLoS Computational Biology : a new community journal}, number = {8}, publisher = {PLoS}, address = {San Fransisco}, issn = {1553-734X}, doi = {10.1371/journal.pcbi.1009268}, pages = {33}, year = {2021}, abstract = {Amoeboid cell motility is essential for a wide range of biological processes including wound healing, embryonic morphogenesis, and cancer metastasis. It relies on complex dynamical patterns of cell shape changes that pose long-standing challenges to mathematical modeling and raise a need for automated and reproducible approaches to extract quantitative morphological features from image sequences. Here, we introduce a theoretical framework and a computational method for obtaining smooth representations of the spatiotemporal contour dynamics from stacks of segmented microscopy images. Based on a Gaussian process regression we propose a one-parameter family of regularized contour flows that allows us to continuously track reference points (virtual markers) between successive cell contours. We use this approach to define a coordinate system on the moving cell boundary and to represent different local geometric quantities in this frame of reference. In particular, we introduce the local marker dispersion as a measure to identify localized membrane expansions and provide a fully automated way to extract the properties of such expansions, including their area and growth time. The methods are available as an open-source software package called AmoePy, a Python-based toolbox for analyzing amoeboid cell motility (based on time-lapse microscopy data), including a graphical user interface and detailed documentation. Due to the mathematical rigor of our framework, we envision it to be of use for the development of novel cell motility models. We mainly use experimental data of the social amoeba Dictyostelium discoideum to illustrate and validate our approach.
Author summary Amoeboid motion is a crawling-like cell migration that plays an important key role in multiple biological processes such as wound healing and cancer metastasis. This type of cell motility results from expanding and simultaneously contracting parts of the cell membrane. From fluorescence images, we obtain a sequence of points, representing the cell membrane, for each time step. By using regression analysis on these sequences, we derive smooth representations, so-called contours, of the membrane. Since the number of measurements is discrete and often limited, the question is raised of how to link consecutive contours with each other. In this work, we present a novel mathematical framework in which these links are described by regularized flows allowing a certain degree of concentration or stretching of neighboring reference points on the same contour. This stretching rate, the so-called local dispersion, is used to identify expansions and contractions of the cell membrane providing a fully automated way of extracting properties of these cell shape changes. We applied our methods to time-lapse microscopy data of the social amoeba Dictyostelium discoideum.}, language = {en} } @article{MatternPudellLaskinetal.2021, author = {Mattern, Maximilian and Pudell, Jan-Etienne and Laskin, Gennadii and Reppert, Alexander von and Bargheer, Matias}, title = {Analysis of the temperature- and fluence-dependent magnetic stress in laser-excited SrRuO3}, series = {Structural dynamics}, volume = {8}, journal = {Structural dynamics}, number = {2}, publisher = {AIP Publishing LLC}, address = {Melville, NY}, issn = {2329-7778}, doi = {10.1063/4.0000072}, pages = {9}, year = {2021}, abstract = {We use ultrafast x-ray diffraction to investigate the effect of expansive phononic and contractive magnetic stress driving the picosecond strain response of a metallic perovskite SrRuO3 thin film upon femtosecond laser excitation. We exemplify how the anisotropic bulk equilibrium thermal expansion can be used to predict the response of the thin film to ultrafast deposition of energy. It is key to consider that the laterally homogeneous laser excitation changes the strain response compared to the near-equilibrium thermal expansion because the balanced in-plane stresses suppress the Poisson stress on the picosecond timescale. We find a very large negative Gr{\"u}neisen constant describing the large contractive stress imposed by a small amount of energy in the spin system. The temperature and fluence dependence of the strain response for a double-pulse excitation scheme demonstrates the saturation of the magnetic stress in the high-fluence regime.}, language = {en} } @article{OloyaNamukobeHeydenreichetal.2021, author = {Oloya, Benson and Namukobe, Jane and Heydenreich, Matthias and Ssengooba, Willy and Schmidt, Bernd and Byamukama, Robert}, title = {Antimycobacterial activity of the extract and isolated compounds from the stem bark of Zanthoxylum leprieurii Guill. and Perr.}, series = {Natural product communications : an international journal for communications and reviews}, volume = {16}, journal = {Natural product communications : an international journal for communications and reviews}, number = {8}, publisher = {Sage Publ.}, address = {Thousand Oaks}, issn = {1934-578X}, doi = {10.1177/1934578X211035851}, pages = {8}, year = {2021}, abstract = {Zanthoxylum leprieurii Guill. and Perr. (Rutaceae) stem bark is used locally in Uganda for treating tuberculosis (TB) and cough-related infections. Lupeol (1), sesamin (2), trans-fagaramide (3), arnottianamide (4), (S)-marmesinin (5), and hesperidin (6) were isolated from the chloroform/methanol (1:1) extract of Z. leprieurii stem bark. Their structures were elucidated using spectroscopic techniques and by comparison with literature data. Furthermore, the extract and isolated compounds were subjected to antimycobacterial activity. The extract exhibited moderate activity against the susceptible (H(37)Rv) TB strain, but weak activity against the multidrug resistant (MDR)-TB strain with minimum inhibitory concentrations (MICs) of 586.0 and 1172.0 mu g/mL, respectively. Compound 3 (trans-fagaramide) showed significant antimycobacterial activity against the susceptible (H(37)Rv) TB strain (MIC 6 mu g/mL), but moderate activity against the MDR-TB strain (MIC 12.2 mu g/mL). Compounds 2, 5, 6, and 1 showed moderate activities against the susceptible (H(37)Rv) strain (MIC 12.2-98.0 mu g/mL) and moderate to weak activities against the MDR-TB strain (MIC 24.4-195.0 mu g/mL). This study reports for the first time the isolation of compounds 1 to 6 from the stem bark of Z leprieurii. trans-Fagaramide (3) may present a vital template in pursuit of novel and highly effective TB drugs.}, language = {en} }