@article{KnoxBrownRindfleischGuentheretal.2020, author = {Knox-Brown, Patrick and Rindfleisch, Tobias and G{\"u}nther, Anne and Balow, Kim and Bremer, Anne and Walther, Dirk and Miettinen, Markus S. and Hincha, Dirk K. and Thalhammer, Anja}, title = {Similar Yet Different}, series = {International Journal of Molecular Sciences}, volume = {21}, journal = {International Journal of Molecular Sciences}, number = {8}, publisher = {Molecular Diversity Preservation International}, address = {Basel}, issn = {1422-0067}, doi = {10.3390/ijms21082794}, pages = {25}, year = {2020}, abstract = {The importance of intrinsically disordered late embryogenesis abundant (LEA) proteins in the tolerance to abiotic stresses involving cellular dehydration is undisputed. While structural transitions of LEA proteins in response to changes in water availability are commonly observed and several molecular functions have been suggested, a systematic, comprehensive and comparative study of possible underlying sequence-structure-function relationships is still lacking. We performed molecular dynamics (MD) simulations as well as spectroscopic and light scattering experiments to characterize six members of two distinct, lowly homologous clades of LEA_4 family proteins from Arabidopsis thaliana. We compared structural and functional characteristics to elucidate to what degree structure and function are encoded in LEA protein sequences and complemented these findings with physicochemical properties identified in a systematic bioinformatics study of the entire Arabidopsis thaliana LEA_4 family. Our results demonstrate that although the six experimentally characterized LEA_4 proteins have similar structural and functional characteristics, differences concerning their folding propensity and membrane stabilization capacity during a freeze/thaw cycle are obvious. These differences cannot be easily attributed to sequence conservation, simple physicochemical characteristics or the abundance of sequence motifs. Moreover, the folding propensity does not appear to be correlated with membrane stabilization capacity. Therefore, the refinement of LEA_4 structural and functional properties is likely encoded in specific patterns of their physicochemical characteristics.}, language = {en} } @article{SinghDaniSharmaetal.2006, author = {Singh, Jasbir and Dani, Harinder M. and Sharma, Reeta and Steinberg, Pablo}, title = {Inhibition of the biosynthesis of SRP polypeptides and secretory proteins by aflatoxin B-1 can disrupt protein targeting}, series = {Cell biochemistry and function}, volume = {24}, journal = {Cell biochemistry and function}, publisher = {Wiley}, address = {Chichester}, issn = {0263-6484}, doi = {10.1027/cbf.1285}, pages = {507 -- 510}, year = {2006}, abstract = {Cell culture and western blotting studies revealed that aflatoxin B-1 (AFB(1)) inhibits the biosynthesis of two of the constituent polypeptides of signal recognition particle (SRP) (SRP54 and 72). SRP escorts polyribosomes carrying signal peptides from free form in the cytosol to the bound form on endoplasmic reticulum (ER) membrane during protein targeting. These effects of AFB(1) on SRP biosynthesis may inhibit the formation of functional SRP Our experiments have further shown that AFB(1) also inhibits the biosynthesis/translocation of a secretory protein, preprolactin, which fails to appear in the lumen of ER consequent to the treatment with this hepatocarcinogen. The results of the experiments presented in this article therefore enable us to infer for the first time that aflatoxin B-1 may inhibit the functioning of SRP as an escort and deplete the ER of polyribosomes for secretory protein synthesis. As these secretory proteins are important components of the plasma membrane, gap junctions and intercellular matrix, their absence from these locations could disturb cell to cell communication leading to tumorigenesis.}, language = {en} } @article{Oberauer2006, author = {Oberauer, Klaus}, title = {Reasoning with conditionals: A test of formal models of four theories}, series = {Cognitive psychology}, volume = {53}, journal = {Cognitive psychology}, number = {3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0010-0285}, doi = {10.1016/j.cogpsych.2006.04.001}, pages = {238 -- 283}, year = {2006}, abstract = {The four dominant theories of reasoning from conditionals are translated into formal models: The theory of mental models (Johnson-Laird, P. N., \& Byrne, R. M. J. (2002). Conditionals: a theory of meaning, pragmatics, and inference. Psychological Review, 109, 646-678), the suppositional theory (Evans, J. S. B. T., \& Over, D. E. (2004). If. Oxford: Oxford University Press), a dual-process variant of the model theory (Verschueren, N., Schaeken, W., \& d'Ydewalle, G. (2005). A dual-process specification of causal conditional reasoning. Thinking \& Reasoning, 11, 278-293), and the probabilistic theory (Oaksford, M., Chater, N., \& Larkin, J. (2000). Probabilities and polarity biases in conditional inference. Journal of Experimental Psychology: Learning, Memory, and Cognition, 26, 883-899). The first three theories are formalized as multinomial models. The models are applied to the frequencies of patterns of acceptance or rejection across the four basic inferences modus ponens, acceptance of the consequent, denial of the antecedent, and modus tollens. Model fits are assessed for two large data sets, one representing reasoning with abstract, basic conditionals, the other reflecting reasoning with pseudo-realistic causal and non-causal conditionals. The best account of the data was provided by a modified version of the mental-model theory, augmented by directionality, and by the dual-process model.}, language = {en} } @article{MohsenKindSobolevetal.2006, author = {Mohsen, Ayman and Kind, Rainer and Sobolev, Stephan Vladimir and Weber, Michael}, title = {Thickness of the lithosphere east of the Dead Sea Transform}, series = {Geophysical journal international}, volume = {167}, journal = {Geophysical journal international}, number = {2}, publisher = {Blackwell}, address = {Oxford}, issn = {0956-540X}, doi = {10.1111/j.1365-246X.2006.03185.x}, pages = {845 -- 852}, year = {2006}, abstract = {We use the S receiver function method to study the lithosphere at the Dead Sea Transform (DST). A temporary network of 22 seismic broad-band stations was operated on both sides of the DST from 2000 to 2001 as part of the DESERT project. We also used data from six additional permanent broad-band seismic stations at the DST and in the surrounding area, that is, in Turkey, Saudi Arabia, Egypt and Cyprus. Clear S-to-P converted phases from the crust-mantle boundary (Moho) and a deeper discontinuity, which we interpret as lithosphere-asthenosphere boundary (LAB) have been observed. The Moho depth (30-38 km) obtained from S receiver functions agrees well with the results from P receiver functions and other geophysical data. We observe thinning of the lithosphere on the eastern side of the DST from 80 km in the north of the Dead Sea to about 65 km at the Gulf of Aqaba. On the western side of the DST, the few data indicate a thin LAB of about 65 km. For comparison, we found a 90-km-thick lithosphere in eastern Turkey and a 160-km-thick lithosphere under the Arabian shield, respectively. These observations support previous suggestions, based on xenolith data, heat flow observations, regional uplift history and geodynamic modelling, that the lithosphere around DST has been significantly thinned in the Late Cenozoic, likely following rifting and spreading of the Red Sea.}, language = {en} } @article{GarciaSteinigerReichetal.2006, author = {Garcia, A. L. and Steiniger, J. and Reich, S. C. and Weickert, M. O. and Harsch, I. and Machowetz, A. and Mohlig, M. and Spranger, Joachim and Rudovich, N. N. and Meuser, F. and Doerfer, J. and Katz, N. and Speth, M. and Zunft, Hans-Joachim Franz and Pfeiffer, Andreas F. H. and Koebnick, Corinna}, title = {Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance}, series = {Hormone and metabolic research}, volume = {38}, journal = {Hormone and metabolic research}, number = {2}, publisher = {Thieme}, address = {Stuttgart}, issn = {0018-5043}, doi = {10.1055/s-2006-955089}, pages = {761 -- 766}, year = {2006}, abstract = {The consumption of arabinoxylan, a soluble fibre fraction, has been shown to improve glycemic control in type 2 diabetic subjects. Soluble dietary fibre may modulate gastrointestinal or adipose tissue hormones regulating food intake. The present study investigated the effects of arabinoxylan consumption on serum glucose, insulin, lipids, leptin, adiponectin and resistin in subjects with impaired glucose tolerance. In a randomized, single-blind, controlled, crossover intervention trial, 11 adults consumed white bread rolls as either placebo or supplemented with 15g arabinoxylan for 6 weeks with a 6-week washout period. Fasting serum glucose, insulin, triglycerides, unesterified fatty acids, apolipoprotein A1 and B, adiponectin, resistin and leptin were assessed before and after intervention. Fasting serum glucose, serum triglycerides and apolipoprotein A-1 were significantly lower during arabinoxylan consumption compared to placebo (p = 0.029, p = 0.047; p = 0.029, respectively). No effects of arabinoxylan were observed for insulin, adiponectin, leptin and resistin as well as for apolipoprotein B, and unesterified fatty acids. In conclusion, the consumption of AX in subjects with impaired glucose tolerance improved fasting serum glucose, and triglycerides. However, this beneficial effect was not accompanied by changes in fasting adipokine concentrations.}, language = {en} } @article{MaaresKeilKozaetal.2018, author = {Maares, Maria and Keil, Claudia and Koza, Jenny and Straubing, Sophia and Schwerdtle, Tanja and Haase, Hajo}, title = {In Vitro Studies on Zinc Binding and Buffering by Intestinal Mucins}, series = {International Journal of Molecular Sciences}, volume = {19}, journal = {International Journal of Molecular Sciences}, number = {9}, issn = {1422-0067}, doi = {10.3390/ijms19092662}, pages = {20}, year = {2018}, abstract = {The investigation of luminal factors influencing zinc availability and accessibility in the intestine is of great interest when analyzing parameters regulating intestinal zinc resorption. Of note, intestinal mucins were suggested to play a beneficial role in the luminal availability of zinc. Their exact zinc binding properties, however, remain unknown and the impact of these glycoproteins on human intestinal zinc resorption has not been investigated in detail. Thus, the aim of this study is to elucidate the impact of intestinal mucins on luminal uptake of zinc into enterocytes and its transfer into the blood. In the present study, in vitro zinc binding properties of mucins were analyzed using commercially available porcine mucins and secreted mucins of the goblet cell line HT-29-MTX. The molecular zinc binding capacity and average zinc binding affinity of these glycoproteins demonstrates that mucins contain multiple zinc-binding sites with biologically relevant affinity within one mucin molecule. Zinc uptake into the enterocyte cell line Caco-2 was impaired by zinc-depleted mucins. Yet this does not represent their form in the intestinal lumen in vivo under zinc adequate conditions. In fact, zinc-uptake studies into enterocytes in the presence of mucins with differing degree of zinc saturation revealed zinc buffering by these glycoproteins, indicating that mucin-bound zinc is still available for the cells. Finally, the impact of mucins on zinc resorption using three-dimensional cultures was studied comparing the zinc transfer of a Caco-2/HT-29-MTX co-culture and conventional Caco-2 monoculture. Here, the mucin secreting co-cultures yielded higher fractional zinc resorption and elevated zinc transport rates, suggesting that intestinal mucins facilitate the zinc uptake into enterocytes and act as a zinc delivery system for the intestinal epithelium.}, language = {en} } @article{Damaschun2021, author = {Damaschun, Ferdinand}, title = {Christian Gottfried Ehrenberg und die Entwicklung der Mikroskop-Technik im 19. Jahrhundert}, series = {HiN : Alexander von Humboldt im Netz = Christian Gottfried Ehrenberg}, volume = {XXII}, journal = {HiN : Alexander von Humboldt im Netz = Christian Gottfried Ehrenberg}, number = {42}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {1617-5239}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-515218}, pages = {119 -- 134}, year = {2021}, abstract = {Ab Mitte der 1820er Jahre erfuhr die Mikroskop- Technik eine st{\"u}rmische Entwicklung. Dadurch, dass es gelang, nach und nach die optischen Fehler zu korrigieren, verbesserte sich die Aufl{\"o}sung bis zum Ende des Jahrhunderts um den Faktor 10 von 3 μm auf 0,3 μm. Um 1820 begann Christian Gottfried Ehrenberg mit mikroskopischen Untersuchungen. Er nutzte zun{\"a}chst ein einfaches N{\"u}rnberger Mikroskop. 1832 erwarb er ein Mikroskop aus der Berliner Werkstatt von Pistor \& Schiek, das er dann zeitlebens nutzte. Ein Vergleich der Leistungsf{\"a}higkeit seines Instruments mit der f{\"u}r seine Untersuchungen notwendigen Aufl{\"o}sung zeigt, dass es f{\"u}r seine Untersuchungen vollkommen gen{\"u}gte. F{\"u}r seine Untersuchungsobjekte entwickelte er Pr{\"a}parationstechniken und Aufbewahrungsmethoden f{\"u}r die Dauerpr{\"a}parate. Da er auch die mikroskopischen Abbildungen bis hin zu den Vorlagen f{\"u}r die Kupfertafeln selbst anfertigte, behielt er den gesamten Prozess von der Pr{\"a}paration bis zum Druck der Ergebnisse stets in der Hand.}, language = {de} } @article{Boehme2021, author = {B{\"o}hme, Katrin}, title = {Das große Ganze. Christian Gottfried Ehrenberg und die Gesellschaft Naturforschender Freunde zu Berlin}, series = {HiN : Alexander von Humboldt im Netz = Christian Gottfried Ehrenberg}, volume = {XXII}, journal = {HiN : Alexander von Humboldt im Netz = Christian Gottfried Ehrenberg}, number = {42}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {1617-5239}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-515226}, pages = {155 -- 169}, year = {2021}, abstract = {Als langj{\"a}hriges und aktives Mitglied der Gesellschaft Naturforschender Freunde zu Berlin bestimmte Ehrenberg ihre Aktivit{\"a}ten und ihr Ansehen maßgeblich mit. Seine Beitr{\"a}ge zu den Sitzungen und Schriften und seine Rolle als Bewohner des gesellschaftseigenen Hauses f{\"o}rderten in der GNF sowohl Fortschritt als auch Best{\"a}ndigkeit. Das Ziel der Naturgeschichte des 18. Jahrhunderts, also die Entdeckung, Beschreibung und Bewahrung m{\"o}glichst aller Organismen- und Gesteinsarten, wurde in der GNF bis in die zweite H{\"a}lfte des 19. Jahrhunderts tradiert. Ehrenbergs wissenschaftliche Leistungen, insbesondere seine zahlreichen Entdeckungen mit Hilfe des Mikroskops, stehen ganz in dieser Tradition.}, language = {de} } @article{NitzeGrosseJonesetal.2018, author = {Nitze, Ingmar and Grosse, Guido and Jones, Benjamin M. and Romanovsky, Vladimir E. and Boike, Julia}, title = {Remote sensing quantifies widespread abundance of permafrost region disturbances across the Arctic and Subarctic}, series = {Nature Communications}, volume = {9}, journal = {Nature Communications}, publisher = {Nature Publ. Group}, address = {London}, issn = {2041-1723}, doi = {10.1038/s41467-018-07663-3}, pages = {11}, year = {2018}, abstract = {Local observations indicate that climate change and shifting disturbance regimes are causing permafrost degradation. However, the occurrence and distribution of permafrost region disturbances (PRDs) remain poorly resolved across the Arctic and Subarctic. Here we quantify the abundance and distribution of three primary PRDs using time-series analysis of 30-m resolution Landsat imagery from 1999 to 2014. Our dataset spans four continental-scale transects in North America and Eurasia, covering similar to 10\% of the permafrost region. Lake area loss (-1.45\%) dominated the study domain with enhanced losses occurring at the boundary between discontinuous and continuous permafrost regions. Fires were the most extensive PRD across boreal regions (6.59\%), but in tundra regions (0.63\%) limited to Alaska. Retrogressive thaw slumps were abundant but highly localized (< 10(-5)\%). Our analysis synergizes the global-scale importance of PRDs. The findings highlight the need to include PRDs in next-generation land surface models to project the permafrost carbon feedback.}, language = {en} } @article{KathBoitGuilletal.2018, author = {Kath, Nadja J. and Boit, Alice and Guill, Christian and Gaedke, Ursula}, title = {Accounting for activity respiration results in realistic trophic transfer efficiencies in allometric trophic network (ATN) models}, series = {Theoretical ecology}, volume = {11}, journal = {Theoretical ecology}, number = {4}, publisher = {Springer}, address = {Heidelberg}, issn = {1874-1738}, doi = {10.1007/s12080-018-0378-z}, pages = {453 -- 463}, year = {2018}, abstract = {Allometric trophic network (ATN) models offer high flexibility and scalability while minimizing the number of parameters and have been successfully applied to investigate complex food web dynamics and their influence on food web diversity and stability. However, the realism of ATN model energetics has never been assessed in detail, despite their critical influence on dynamic biomass and production patterns. Here, we compare the energetics of the currently established original ATN model, considering only biomass-dependent basal respiration, to an extended ATN model version, considering both basal and assimilation-dependent activity respiration. The latter is crucial in particular for unicellular and invertebrate organisms which dominate the metabolism of pelagic and soil food webs. Based on metabolic scaling laws, we show that the extended ATN version reflects the energy transfer through a chain of four trophic levels of unicellular and invertebrate organisms more realistically than the original ATN version. Depending on the strength of top-down control, the original ATN model yields trophic transfer efficiencies up to 71\% at either the third or the fourth trophic level, which considerably exceeds any realistic values. In contrast, the extended ATN version yields realistic trophic transfer efficiencies 30\% at all trophic levels, in accordance with both physiological considerations and empirical evidence from pelagic systems. Our results imply that accounting for activity respiration is essential for consistently implementing the metabolic theory of ecology in ATN models and for improving their quantitative predictions, which makes them more powerful tools for investigating the dynamics of complex natural communities.}, language = {en} } @misc{FritzRosaSicard2018, author = {Fritz, Michael Andre and Rosa, Stefanie and Sicard, Adrien}, title = {Mechanisms Underlying the Environmentally Induced Plasticity of Leaf Morphology}, series = {Frontiers in genetics}, volume = {9}, journal = {Frontiers in genetics}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-8021}, doi = {10.3389/fgene.2018.00478}, pages = {25}, year = {2018}, abstract = {The primary function of leaves is to provide an interface between plants and their environment for gas exchange, light exposure and thermoregulation. Leaves have, therefore a central contribution to plant fitness by allowing an efficient absorption of sunlight energy through photosynthesis to ensure an optimal growth. Their final geometry will result from a balance between the need to maximize energy uptake while minimizing the damage caused by environmental stresses. This intimate relationship between leaf and its surroundings has led to an enormous diversification in leaf forms. Leaf shape varies between species, populations, individuals or even within identical genotypes when those are subjected to different environmental conditions. For instance, the extent of leaf margin dissection has, for long, been found to inversely correlate with the mean annual temperature, such that Paleobotanists have used models based on leaf shape to predict the paleoclimate from fossil flora. Leaf growth is not only dependent on temperature but is also regulated by many other environmental factors such as light quality and intensity or ambient humidity. This raises the question of how the different signals can be integrated at the molecular level and converted into clear developmental decisions. Several recent studies have started to shed the light on the molecular mechanisms that connect the environmental sensing with organ-growth and patterning. In this review, we discuss the current knowledge on the influence of different environmental signals on leaf size and shape, their integration as well as their importance for plant adaptation.}, language = {en} } @article{WaltherGuanterHeimetal.2018, author = {Walther, Sophia and Guanter, Luis and Heim, Birgit and Jung, Martin and Duveiller, Gregory and Wolanin, Aleksandra and Sachs, Torsten}, title = {Assessing the dynamics of vegetation productivity in circumpolar regions with different satellite indicators of greenness and photosynthesis}, series = {Biogeosciences}, volume = {15}, journal = {Biogeosciences}, number = {20}, publisher = {Copernicus}, address = {G{\"o}ttingen}, issn = {1726-4170}, doi = {10.5194/bg-15-6221-2018}, pages = {6221 -- 6256}, year = {2018}, abstract = {High-latitude treeless ecosystems represent spatially highly heterogeneous landscapes with small net carbon fluxes and a short growing season. Reliable observations and process understanding are critical for projections of the carbon balance of the climate-sensitive tundra. Space-borne remote sensing is the only tool to obtain spatially continuous and temporally resolved information on vegetation greenness and activity in remote circumpolar areas. However, confounding effects from persistent clouds, low sun elevation angles, numerous lakes, widespread surface inundation, and the sparseness of the vegetation render it highly challenging. Here, we conduct an extensive analysis of the timing of peak vegetation productivity as shown by satellite observations of complementary indicators of plant greenness and photosynthesis. We choose to focus on productivity during the peak of the growing season, as it importantly affects the total annual carbon uptake. The suite of indicators are as follows: (1) MODIS-based vegetation indices (VIs) as proxies for the fraction of incident photosynthetically active radiation (PAR) that is absorbed (fPAR), (2) VIs combined with estimates of PAR as a proxy of the total absorbed radiation (APAR), (3) sun-induced chlorophyll fluorescence (SIF) serving as a proxy for photosynthesis, (4) vegetation optical depth (VOD), indicative of total water content and (5) empirically upscaled modelled gross primary productivity (GPP). Averaged over the pan-Arctic we find a clear order of the annual peak as APAR <= GPP < SIF < VIs/VOD. SIF as an indicator of photosynthesis is maximised around the time of highest annual temperatures. The modelled GPP peaks at a similar time to APAR. The time lag of the annual peak between APAR and instantaneous SIF fluxes indicates that the SIF data do contain information on light-use efficiency of tundra vegetation, but further detailed studies are necessary to verify this. Delayed peak greenness compared to peak photosynthesis is consistently found across years and land-cover classes. A particularly late peak of the normalised difference vegetation index (NDVI) in regions with very small seasonality in greenness and a high amount of lakes probably originates from artefacts. Given the very short growing season in circumpolar areas, the average time difference in maximum annual photosynthetic activity and greenness or growth of 3 to 25 days (depending on the data sets chosen) is important and needs to be considered when using satellite observations as drivers in vegetation models.}, language = {en} } @article{KabothBahrBahrZeedenetal.2021, author = {Kaboth-Bahr, Stefanie and Bahr, Andr{\´e} and Zeeden, Christian and Yamoah, Kweku A. and Lone, Mahjoor Ahmad and Chuang, Chih-Kai and L{\"o}wemark, Ludvig and Wei, Kuo-Yen}, title = {A tale of shifting relations}, series = {Scientific Reports}, volume = {11}, journal = {Scientific Reports}, publisher = {Macmillan Publishers Limited, part of Springer Nature}, address = {London}, issn = {2045-2322}, doi = {10.1038/s41598-021-85444-7}, pages = {10}, year = {2021}, abstract = {Understanding the dynamics between the East Asian summer (EASM) and winter monsoon (EAWM) is needed to predict their variability under future global warming scenarios. Here, we investigate the relationship between EASM and EAWM as well as the mechanisms driving their variability during the last 10,000 years by stacking marine and terrestrial (non-speleothem) proxy records from the East Asian realm. This provides a regional and proxy independent signal for both monsoonal systems. The respective signal was subsequently analysed using a linear regression model. We find that the phase relationship between EASM and EAWM is not time-constant and significantly depends on orbital configuration changes. In addition, changes in the Atlantic Meridional Overturning circulation, Arctic sea-ice coverage, El Ni{\~n}o-Southern Oscillation and Sun Spot numbers contributed to millennial scale changes in the EASM and EAWM during the Holocene. We also argue that the bulk signal of monsoonal activity captured by the stacked non-speleothem proxy records supports the previously argued bias of speleothem climatic archives to moisture source changes and/or seasonality.}, language = {en} } @article{SchaalRutlohWeidenfeldetal.2018, author = {Schaal, Frederik and Rutloh, Michael and Weidenfeld, Susanne and Stumpe, Joachim and Michler, Peter and Pruss, Christof and Osten, Wolfgang}, title = {Optically addressed modulator for tunable spatial polarization control}, series = {Optics express : the international electronic journal of optics}, volume = {26}, journal = {Optics express : the international electronic journal of optics}, number = {21}, publisher = {Optical Society of America}, address = {Washington}, issn = {1094-4087}, doi = {10.1364/OE.26.028119}, pages = {28119 -- 28130}, year = {2018}, abstract = {We present an optically addressed non-pixelated spatial light modulator. The system is based on reversible photoalignment of a LC cell using a red light sensitive novel azobenzene photoalignment layer. It is an electrode-free device that manipulates the liquid crystal orientation and consequently the polarization via light without artifacts caused by electrodes. The capability to miniaturize the spatial light modulator allows the integration into a microscope objective. This includes a miniaturized 200 channel optical addressing system based on a VCSEL array and hybrid refractive-diffractive beam shapers. As an application example, the utilization as a microscope objective integrated analog phase contrast modulator is shown. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement}, language = {en} } @article{PengLiuWangetal.2018, author = {Peng, Junjie and Liu, Danxu and Wang, Yingtao and Zeng, Ying and Cheng, Feng and Zhang, Wenqiang}, title = {Weight-based strategy for an I/O-intensive application at a cloud data center}, series = {Concurrency and computation : practice \& experience}, volume = {30}, journal = {Concurrency and computation : practice \& experience}, number = {19}, publisher = {Wiley}, address = {Hoboken}, issn = {1532-0626}, doi = {10.1002/cpe.4648}, pages = {14}, year = {2018}, abstract = {Applications with different characteristics in the cloud may have different resources preferences. However, traditional resource allocation and scheduling strategies rarely take into account the characteristics of applications. Considering that an I/O-intensive application is a typical type of application and that frequent I/O accesses, especially small files randomly accessing the disk, may lead to an inefficient use of resources and reduce the quality of service (QoS) of applications, a weight allocation strategy is proposed based on the available resources that a physical server can provide as well as the characteristics of the applications. Using the weight obtained, a resource allocation and scheduling strategy is presented based on the specific application characteristics in the data center. Extensive experiments show that the strategy is correct and can guarantee a high concurrency of I/O per second (IOPS) in a cloud data center with high QoS. Additionally, the strategy can efficiently improve the utilization of the disk and resources of the data center without affecting the service quality of applications.}, language = {en} } @article{SeissAlbersSremčevićetal.2019, author = {Seiß, Martin and Albers, Nicole and Sremčević, Miodrag and Schmidt, J{\"u}rgen and Salo, Heikki and Seiler, Michael and Hoffmann, Holger and Spahn, Frank}, title = {Hydrodynamic Simulations of Moonlet-induced Propellers in Saturn's Rings}, series = {The astronomical journal}, volume = {157}, journal = {The astronomical journal}, number = {1}, publisher = {IOP Publishing Ltd.}, address = {Bristol}, issn = {0004-6256}, doi = {10.3847/1538-3881/aaed44}, pages = {11}, year = {2019}, abstract = {One of the biggest successes of the Cassini mission is the detection of small moons (moonlets) embedded in Saturns rings that cause S-shaped density structures in their close vicinity, called propellers. Here, we present isothermal hydrodynamic simulations of moonlet-induced propellers in Saturn's A ring that denote a further development of the original model. We find excellent agreement between these new hydrodynamic and corresponding N-body simulations. Furthermore, the hydrodynamic simulations confirm the predicted scaling laws and the analytical solution for the density in the propeller gaps. Finally, this mean field approach allows us to simulate the pattern of the giant propeller Bl{\´e}riot, which is too large to be modeled by direct N-body simulations. Our results are compared to two stellar occultation observations by the Cassini Ultraviolet Imaging Spectrometer (UVIS), which intersect the propeller Bl{\´e}riot. Best fits to the UVIS optical depth profiles are achieved for a Hill radius of 590 m, which implies a moonlet diameter of about 860 m. Furthermore, the model favors a kinematic shear viscosity of the surrounding ring material of ν0 = 340 cm2 s-1, a dispersion velocity in the range of 0.3 cm s-1 < c0 < 1.5 cm s-1, and a fairly high bulk viscosity 7 < ξ0/ν0 < 17. These large transport values might be overestimated by our isothermal ring model and should be reviewed by an extended model including thermal fluctuations.}, language = {en} } @article{TraxlerHanssenLautenbacheretal.2018, author = {Traxler, Juliane and Hanssen, Marjolein M. and Lautenbacher, Stefan and Ottawa, Fabian and Peters, Madelon L.}, title = {General versus pain-specific cognitions}, series = {European journal of pain}, volume = {23}, journal = {European journal of pain}, number = {1}, publisher = {Wiley}, address = {Hoboken}, issn = {1090-3801}, doi = {10.1002/ejp.1294}, pages = {150 -- 159}, year = {2018}, abstract = {Background Previous studies found evidence that dispositional optimism is related to lower pain sensitivity. Recent findings suggest that temporarily increasing optimism by means of imagining a positive future may also have pain-alleviating effects. Objectives The present experiment was designed to investigate conditioned pain modulation (CPM) as a potential underlying mechanism of this pain-alleviating effect of induced optimism. Methods For this purpose, 45 healthy participants were randomized into an optimistic or neutral imagery condition. Additionally, participants completed questionnaires on dispositional optimism, pain catastrophizing and pain expectations. CPM was assessed by delivering a series of five heat pain stimuli on the nondominant hand before and during immersion of the dominant hand in water of 5 degrees C for 70 s. Results A clear CPM effect was found, that is heat pain reports were lower during simultaneous cold water stimulation. Although the optimism manipulation successfully increased optimism, it did not affect pain ratings or CPM. Post hoc analyses indicated that dispositional optimism was not associated with the magnitude of CPM, but pain catastrophizing and pain expectations did significantly correlate with the CPM effect. Conclusion Pain-specific but not general cognitions appear to influence endogenous pain modulation. Significance Conditioned pain modulation is not the underlying mechanism of the pain-alleviating effects of induced optimism. However, pain-specific cognitions including pain catastrophizing and pain expectations affect endogenous pain modulation which should be taken into account in treatment and CPM research.}, language = {en} } @article{SalzwedelHeidlerMengetal.2020, author = {Salzwedel, Annett and Heidler, Maria-Dorothea and Meng, Karin and Schikora, Martin and Wegscheider, Karl and Reibis, Rona Katharina and V{\"o}ller, Heinz}, title = {Impact of cognitive performance on disease-related knowledge six months after multi-component rehabilitation in patients after an acute cardiac event}, series = {European journal of preventive cardiology : the official ESC journal for primary \& secondary cardiovascular prevention, rehabilitation and sports cardiology}, volume = {26}, journal = {European journal of preventive cardiology : the official ESC journal for primary \& secondary cardiovascular prevention, rehabilitation and sports cardiology}, number = {1}, publisher = {Sage Publ.}, address = {London}, issn = {2047-4873}, doi = {10.1177/2047487318791609}, pages = {46 -- 55}, year = {2020}, abstract = {Background Although associations between cardiovascular diseases and cognitive impairment are well known, the impact of cognitive performance on the success of patient education as a core component of cardiac rehabilitation remains insufficiently investigated so far. Design Prospective observational study in two inpatient cardiac rehabilitation centres between September 2014 and August 2015 with a follow-up six months after cardiac rehabilitation. Method At admission to and discharge from cardiac rehabilitation, the cognitive performance of 401 patients (54.5 ± 6.3 years, 80\% men) following an acute coronary syndrome and/or coronary artery bypass graft was tested using the Montreal Cognitive Assessment. Patients' disease-related knowledge was determined using a quiz (22 items for medical knowledge and 12 items for healthy lifestyle and behaviour) at both times and at follow-up. The change in knowledge after cardiac rehabilitation was analysed in multivariable regression models. Potentially influencing parameters (e.g. level of education, medication, cardiovascular risk factors, coronary artery bypass graft, comorbidities, exercise capacity) were considered. Results During cardiac rehabilitation, disease-related knowledge was significantly enhanced in both scales. At follow-up, the average level of medical knowledge was significantly reduced, while lifestyle knowledge remained at a stable level. The maintenance of knowledge after cardiac rehabilitation was predominantly predicted by prior knowledge, cognitive performance at discharge from cardiac rehabilitation and, in the case of medical knowledge, by coronary artery bypass graft. Conclusion Patient education in cardiac rehabilitation led to enhanced disease-related knowledge, but the maintenance of this essentially depended on patients' cognitive performance, especially after coronary artery bypass graft. Therefore, patient education concepts in cardiac rehabilitation should be reconsidered and adjusted as needed.}, language = {en} } @article{MaesPerringVanhellemontetal.2018, author = {Maes, Sybryn L. and Perring, Michael P. and Vanhellemont, Margot and Depauw, Leen and Van den Bulcke, Jan and Brumelis, Guntis and Brunet, Jorg and Decocq, Guillaume and den Ouden, Jan and H{\"a}rdtle, Werner and Hedl, Radim and Heinken, Thilo and Heinrichs, Steffi and Jaroszewicz, Bogdan and Kopeck{\´y}, Martin and Malis, Frantisek and Wulf, Monika and Verheyen, Kris}, title = {Environmental drivers interactively affect individual tree growth across temperate European forests}, series = {Global change biology}, volume = {25}, journal = {Global change biology}, number = {1}, publisher = {Wiley}, address = {Hoboken}, issn = {1354-1013}, doi = {10.1111/gcb.14493}, pages = {201 -- 217}, year = {2018}, abstract = {Forecasting the growth of tree species to future environmental changes requires abetter understanding of its determinants. Tree growth is known to respond to global-change drivers such as climate change or atmospheric deposition, as well as to localland-use drivers such as forest management. Yet, large geographical scale studiesexamining interactive growth responses to multiple global-change drivers are relativelyscarce and rarely consider management effects. Here, we assessed the interactiveeffects of three global-change drivers (temperature, precipitation and nitrogen deposi-tion) on individual tree growth of three study species (Quercus robur/petraea, Fagus syl-vatica and Fraxinus excelsior). We sampled trees along spatial environmental gradientsacross Europe and accounted for the effects of management for Quercus. We collectedincrement cores from 267 trees distributed over 151 plots in 19 forest regions andcharacterized their neighbouring environment to take into account potentially confounding factors such as tree size, competition, soil conditions and elevation. Wedemonstrate that growth responds interactively to global-change drivers, with species -specific sensitivities to the combined factors. Simultaneously high levels of precipita-tion and deposition benefited Fraxinus, but negatively affected Quercus' growth, high-lighting species-specific interactive tree growth responses to combined drivers. ForFagus, a stronger growth response to higher temperatures was found when precipita-tion was also higher, illustrating the potential negative effects of drought stress underwarming for this species. Furthermore, we show that past forest management canmodulate the effects of changing temperatures on Quercus' growth; individuals in plotswith a coppicing history showed stronger growth responses to higher temperatures.Overall, our findings highlight how tree growth can be interactively determined by glo-bal-change drivers, and how these growth responses might be modulated by past for-est management. By showing future growth changes for scenarios of environmentalchange, we stress the importance of considering multiple drivers, including past man-agement and their interactions, when predicting tree growth.}, language = {en} } @article{MeiserEsser2017, author = {Meiser, Susanne and Esser, G{\"u}nter}, title = {Interpersonal Stress Generation-A Girl Problem?}, series = {Journal of early adolescence}, volume = {39}, journal = {Journal of early adolescence}, number = {1}, publisher = {Sage Publ.}, address = {Thousand Oaks}, issn = {0272-4316}, doi = {10.1177/0272431617725197}, pages = {41 -- 66}, year = {2017}, abstract = {To provide further insight into stress generation patterns in boys and girls around puberty, this study investigated longitudinal reciprocal relations between depressive symptoms, dysfunctional attitudes, and stress generation, the process by which individuals contribute to the occurrence of stress in interpersonal contexts (e.g., problematic social interactions) or in noninterpersonal contexts (e.g., achievement problems). A community sample of N = 924 German children and early adolescents (51.8\% male) completed depressive symptoms and dysfunctional attitudes measures at T1 and again 20 months later (T2). Stressful life events were reported at T2. Dysfunctional attitudes were unrelated to stress generation. Interpersonal, but not noninterpersonal, dependent stress partially mediated the relationship between initial and later depressive symptoms, with girls being more likely to generate interpersonal stress in response to depressive symptoms. Findings underscore the role of interpersonal stress generation in the early development of depressive symptomatology, and in the gender difference in depression prevalence emerging around puberty.}, language = {en} } @article{PourteauSchererSchornetal.2019, author = {Pourteau, Amaury and Scherer, Erik E. and Schorn, Simon and Bast, Rebecca and Schmidt, Alexander and Ebert, Lisa}, title = {Thermal evolution of an ancient subduction interface revealed by Lu-Hf garnet geochronology, Halilbagi Complex (Anatolia)}, series = {Geoscience Frontiers}, volume = {10}, journal = {Geoscience Frontiers}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1674-9871}, doi = {10.1016/j.gsf.2018.03.004}, pages = {127 -- 148}, year = {2019}, abstract = {The thermal structure of subduction zones exerts a major influence on deep-seated mechanical and chemical processes controlling arc magmatism, seismicity, and global element cycles. Accretionary complexes exposed inland may comprise tectonic blocks with contrasting pressure-temperature (P-T) histories, making it possible to investigate the dynamics and thermal evolution of former subduction interfaces. With this aim, we present new Lu-Hf geochronological results for mafic rocks of the Halilbagi Complex (Anatolia) that evolved along different thermal gradients. Samples include a lawsonite-epidote blueschist, a lawsonite-epidote eclogite, and an epidote eclogite (all with counter-clockwise P-T paths), a prograde lawsonite blueschist with a "hairpin"-type P-T path, and a garnet amphibolite from the overlying sub-ophiolitic metamorphic sole. Equilibrium phase diagrams suggest that the garnet amphibolite formed at similar to 0.6-0.7 GPa and 800-850 degrees C, whereas the prograde lawsonite blueschist records burial from 2.1 GPa and 420 degrees C to 2.6 GPa and 520 degrees C. Well-defined Lu-Hf isochrons were obtained for the epidote eclogite (92.38 +/- 0.22 Ma) and the lawsonite-epidote blueschist (90.19 +/- 0.54 Ma), suggesting rapid garnet growth. The lawsonite-epidote eclogite (87.30 +/- 0.39 Ma) and the prograde lawsonite blueschist (ca. 86 Ma) are younger, whereas the garnet amphibolite (104.5 +/- 3.5 Ma) is older. Our data reveal a consistent trend of progressively decreasing geothermal gradient from granulite-facies conditions at similar to 104 Ma to the epidote-eclogite facies around 92 Ma, and the lawsonite blueschist-facies between 90 Ma and 86 Ma. Three Lu-Hf garnet dates (between 92 Ma and 87 Ma) weighted toward the growth of post-peak rims (as indicated by Lu distribution in garnet) suggest that the HP/LT rocks were exhumed continuously and not episodically. We infer that HP/LT metamorphic rocks within the Halilbagi Complex were subjected to continuous return flow, with "warm" rocks being exhumed during the tectonic burial of "cold" ones. Our results, combined with regional geological constraints, allow us to speculate that subduction started at a transform fault near a mid-oceanic spreading centre. Following its formation, this ancient subduction interface evolved thermally over more than 15 Myr, most likely as a result of heat dissipation rather than crustal underplating. (C) 2018, China University of Geosciences (Beijing) and Peking University. Production and hosting by Elsevier B.V.}, language = {en} } @article{ColomaGaedkeSivonenetal.2019, author = {Coloma, Sebastian and Gaedke, Ursula and Sivonen, Kaarina and Hiltunen, Teppo}, title = {Frequency of virus-resistant hosts determines experimental community dynamics}, series = {Ecology : a publication of the Ecological Society of America}, volume = {100}, journal = {Ecology : a publication of the Ecological Society of America}, number = {1}, publisher = {Wiley}, address = {Hoboken}, issn = {0012-9658}, doi = {10.1002/ecy.2554}, pages = {10}, year = {2019}, abstract = {Parasites, such as bacterial viruses (phages), can have large effects on host populations both at the ecological and evolutionary levels. In the case of cyanobacteria, phages can reduce primary production and infected hosts release intracellular nutrients influencing planktonic food web structure, community dynamics, and biogeochemical cycles. Cyanophages may be of great importance in aquatic food webs during large cyanobacterial blooms unless the host population becomes resistant to phage infection. The consequences on plankton community dynamics of the evolution of phage resistance in bloom forming cyanobacterial populations are still poorly studied. Here, we examined the effect of different frequencies of a phage-resistant genotype within a filamentous nitrogen-fixing Nodularia spumigena population on an experimental plankton community. Three Nodularia populations with different initial frequencies (0\%, 5\%, and 50\%) of phage-resistant genotypes were inoculated in separate treatments with the phage 2AV2, the green alga Chlorella vulgaris, and the rotifer Brachionus plicatilis, which formed the experimental plankton community subjected to either nitrogen-limited or nitrogen-rich conditions. We found that the frequency of the phage-resistant Nodularia genotype determined experimental community dynamics. Cyanobacterial populations with a high frequency (50\%) of the phage-resistant genotype dominated the cultures despite the presence of phages, retaining most of the intracellular nitrogen in the plankton community. In contrast, populations with low frequencies (0\% and 5\%) of the phage-resistant genotype were lysed and reduced to extinction by the phage, transferring the intracellular nitrogen held by Nodularia to Chlorella and rotifers, and allowing Chlorella to dominate the communities and rotifers to survive. This study shows that even though phages represent minuscule biomass, they can have key effects on community composition and eco-evolutionary feedbacks in plankton communities.}, language = {en} } @article{FosterHeindelRichozetal.2019, author = {Foster, William J. and Heindel, Katrin and Richoz, Sylvain and Gliwa, Jana and Lehrmann, Daniel J. and Baud, Aymon and Kolar-Jurkovsek, Tea and Aljinovic, Dunja and Jurkovsek, Bogdan and Korn, Dieter and Martindale, Rowan C. and Peckmann, J{\"o}rn}, title = {Suppressed competitive exclusion enabled the proliferation of Permian/Triassic boundary microbialites}, series = {The Depositional Record : the open access journal of the International Association of Sedimentologists}, volume = {6}, journal = {The Depositional Record : the open access journal of the International Association of Sedimentologists}, number = {1}, publisher = {Wiley}, address = {Hoboken}, issn = {2055-4877}, doi = {10.1002/dep2.97}, pages = {62 -- 74}, year = {2019}, abstract = {During the earliest Triassic microbial mats flourished in the photic zones of marginal seas, generating widespread microbialites. It has been suggested that anoxic conditions in shallow marine environments, linked to the end-Permian mass extinction, limited mat-inhibiting metazoans allowing for this microbialite expansion. The presence of a diverse suite of proxies indicating oxygenated shallow sea-water conditions (metazoan fossils, biomarkers and redox proxies) from microbialite successions have, however, challenged the inference of anoxic conditions. Here, the distribution and faunal composition of Griesbachian microbialites from China, Iran, Turkey, Armenia, Slovenia and Hungary are investigated to determine the factors that allowed microbialite-forming microbial mats to flourish following the end-Permian crisis. The results presented here show that Neotethyan microbial buildups record a unique faunal association due to the presence of keratose sponges, while the Palaeotethyan buildups have a higher proportion of molluscs and the foraminifera Earlandia. The distribution of the faunal components within the microbial fabrics suggests that, except for the keratose sponges and some microconchids, most of the metazoans were transported into the microbial framework via wave currents. The presence of both microbialites and metazoan associations were limited to oxygenated settings, suggesting that a factor other than anoxia resulted in a relaxation of ecological constraints following the mass extinction event. It is inferred that the end-Permian mass extinction event decreased the diversity and abundance of metazoans to the point of significantly reducing competition, allowing photosynthesis-based microbial mats to flourish in shallow water settings and resulting in the formation of widespread microbialites.}, language = {en} } @article{BarthGeertsemaBevingtonetal.2019, author = {Barth, Sophia and Geertsema, Marten and Bevington, Alexandre R. and Bird, Alison L. and Clague, John J. and Millard, Tom and Bobrowsky, Peter T. and Hasler, Andreas and Liu, Hongjiang}, title = {Landslide response to the 27 October 2012 earthquake (M-W 7.8), southern Haida Gwaii, British Columbia, Canada}, series = {Landslides : journal of the International Consortium on Landslides, ICL}, volume = {17}, journal = {Landslides : journal of the International Consortium on Landslides, ICL}, number = {3}, publisher = {Springer}, address = {Heidelberg}, issn = {1612-510X}, doi = {10.1007/s10346-019-01292-7}, pages = {517 -- 526}, year = {2019}, abstract = {In this paper, we examine the influence of the 27 October 2012, M-w 7.8 earthquake on landslide occurrence in the southern half of Haida Gwaii (formerly Queen Charlotte Islands), British Columbia, Canada. Our 1350 km(2) study area is undisturbed, primarily forested terrain that has not experienced road building or timber harvesting. Our inventory of landslide polygons is based on optical airborne and spaceborne images acquired between 2007 and 2018, from which we extracted and mapped 446 individual landslides (an average of 33 landslides per 100 km(2)). The landslide rate in years without major earthquakes averages 19.4 per year, or 1.4/100 km(2)/year, and the annual average area covered by non-seismically triggered landslides is 35 ha/year. The number of landslides identified in imagery closely following the 2012 earthquake, and probably triggered by it, is 244 or an average of about 18 landslides per 100 km(2). These landslides cover a total area of 461 ha. In the following years-2013-2016 and 2016-2018-the number of landslides fell, respectively, to 26 and 13.5 landslides per year. In non-earthquake years, most landslides happen on south-facing slopes, facing the prevailing winds. In contrast, during or immediately after the earthquake, up to 32\% of the landslides occurred on north and northwest-facing slopes. Although we could not find imagery from the day after the earthquake, overview reconnaissance flights 10 and 16 days later showed that most of the landslides were recent, suggesting they were co-seismic.}, language = {en} } @article{RyoJeschkeRilligetal.2020, author = {Ryo, Masahiro and Jeschke, Jonathan M. and Rillig, Matthias C. and Heger, Tina}, title = {Machine learning with the hierarchy-of-hypotheses (HoH) approach discovers novel pattern in studies on biological invasions}, series = {Research synthesis methods}, volume = {11}, journal = {Research synthesis methods}, number = {1}, publisher = {Wiley}, address = {Hoboken}, issn = {1759-2879}, doi = {10.1002/jrsm.1363}, pages = {66 -- 73}, year = {2020}, abstract = {Research synthesis on simple yet general hypotheses and ideas is challenging in scientific disciplines studying highly context-dependent systems such as medical, social, and biological sciences. This study shows that machine learning, equation-free statistical modeling of artificial intelligence, is a promising synthesis tool for discovering novel patterns and the source of controversy in a general hypothesis. We apply a decision tree algorithm, assuming that evidence from various contexts can be adequately integrated in a hierarchically nested structure. As a case study, we analyzed 163 articles that studied a prominent hypothesis in invasion biology, the enemy release hypothesis. We explored if any of the nine attributes that classify each study can differentiate conclusions as classification problem. Results corroborated that machine learning can be useful for research synthesis, as the algorithm could detect patterns that had been already focused in previous narrative reviews. Compared with the previous synthesis study that assessed the same evidence collection based on experts' judgement, the algorithm has newly proposed that the studies focusing on Asian regions mostly supported the hypothesis, suggesting that more detailed investigations in these regions can enhance our understanding of the hypothesis. We suggest that machine learning algorithms can be a promising synthesis tool especially where studies (a) reformulate a general hypothesis from different perspectives, (b) use different methods or variables, or (c) report insufficient information for conducting meta-analyses.}, language = {en} } @misc{vanderKroefKoszinskiGrinatetal.2020, author = {van der Kroef, Ilona and Koszinski, Sylvia and Grinat, Michael and van der Meij, Marijn W. and Hierold, Wilfried and S{\"u}dekum, Wolfgang and Sommer, Michael}, title = {Digital mapping of buried soil horizons using 2D and pseudo-3D geoelectrical measurements in a ground moraine landscape}, series = {European journal of soil science : EJSS}, volume = {71}, journal = {European journal of soil science : EJSS}, number = {1}, publisher = {Wiley}, address = {Hoboken}, issn = {1351-0754}, pages = {10 -- 26}, year = {2020}, abstract = {The identification of buried soil horizons in agricultural landscapes helps to quantify sediment budgets and erosion-related carbon dynamics. High-resolution mapping of buried horizons using conventional soil surveys is destructive and time consuming. Geoelectrical sensors can offer a fast and non-destructive alternative for determining horizon positions and properties. In this paper, we compare the suitability of several geoelectrical methods for measuring the depth to buried horizons (Apb, Ahb and Hab) in the hummocky ground moraine landscape of northeastern Germany. Soil profile descriptions were developed for 269 locations within a 6-ha experimental field "CarboZALF-D". A stepwise linear discriminant analysis (LDA) estimated the lateral position of the buried horizons using electromagnetic induction data and terrain attributes. To predict the depth of a buried horizon, multiple linear regression (MLR) was used for both a 120-m transect and a 0.2-ha pseudo-three-dimensional (3D) area. At these scales, apparent electrical conductivity (ECa), electrical resistivity (ER) and terrain attributes were used as independent variables. The LDA accurately predicted Apb- and Ahb-horizons (a correct classification of 93\%). The LDA of the Hab-horizon had a misclassification of 24\%, which was probably related to the smaller test set and the higher depth of this horizon. The MLR predicted the depth of the Apb-, Ahb- and Hab-horizons with relative root mean square errors (RMSEs) of 7, 3 and 13\%, respectively, in the pseudo-3D area. MLR had a lower accuracy for the 2D transect compared to the pseudo-3D area. Overall, the use of LDA and MLR has been an efficient methodological approach for predicting buried horizon positions. Highlights The suitability of geoelectrical measurements for digital modelling of diagnostic buried soil horizons was determined. LDA and MLR were used to detect multiple horizons with geoelectrical devices and terrain attributes. Geoelectrical variables were significant predictors of the position of the target soil horizons. The use of these tested digital technologies gives an opportunity to develop high-resolution soil mapping procedures.}, language = {en} } @article{SchaubKlaassenBoutenetal.2020, author = {Schaub, Tonio and Klaassen, Raymond H. G. and Bouten, Willem and Schlaich, Almut E. and Koks, Ben J.}, title = {Collision risk of Montagu's Harriers Circus pygargus with wind turbines derived from high-resolution GPS tracking}, series = {Ibis : the international journal of avian science ; the journal of the British Ornithologists' Union}, volume = {162}, journal = {Ibis : the international journal of avian science ; the journal of the British Ornithologists' Union}, number = {2}, publisher = {Wiley}, address = {Hoboken}, issn = {0019-1019}, doi = {10.1111/ibi.12788}, pages = {520 -- 534}, year = {2020}, abstract = {Flight behaviour characteristics such as flight altitude and avoidance behaviour determine the species-specific collision risk of birds with wind turbines. However, traditional observational methods exhibit limited positional accuracy. High-resolution GPS telemetry represents a promising method to overcome this drawback. In this study, we used three-dimensional GPS tracking data including high-accuracy tracks recorded at 3-s intervals to investigate the collision risk of breeding male Montagu's Harriers Circus pygargus in the Dutch-German border region. Avoidance of wind turbines was quantified by a novel approach comparing observed flights to a null model of random flight behaviour. On average, Montagu's Harriers spent as much as 8.2 h per day in flight. Most flights were at low altitude, with only 7.1\% within the average rotor height range (RHR; 45-125 m). Montagu's Harriers showed significant avoidance behaviour, approaching turbines less often than expected, particularly when flying within the RHR (avoidance rate of 93.5\%). For the present state, with wind farms situated on the fringes of the regional nesting range, collision risk models based on our new insights on flight behaviour indicated 0.6-2.0 yearly collisions of adult males (as compared with a population size of c. 40 pairs). However, the erection of a new wind farm inside the core breeding area could markedly increase mortality (up to 9.7 yearly collisions). If repowering of the wind farms was carried out using low-reaching modern turbines (RHR 36-150 m), mortality would more than double, whereas it would stay approximately constant if higher turbines (RHR 86-200 m) were used. Our study demonstrates the great potential of high-resolution GPS tracking for collision risk assessments. The resulting information on collision-related flight behaviour allows for performing detailed scenario analyses on wind farm siting and turbine design, in contrast to current environmental assessment practices. With regard to Montagu's Harriers, we conclude that although the deployment of higher wind turbines represents an opportunity to reduce collision risk for this species, precluding wind energy developments in core breeding areas remains the most important mitigation measure.}, language = {en} } @article{Herzschuh2019, author = {Herzschuh, Ulrike}, title = {Legacy of the Last Glacial on the present-day distribution of deciduous versus evergreen boreal forests}, series = {Global ecology and biogeography : a journal of macroecology}, volume = {29}, journal = {Global ecology and biogeography : a journal of macroecology}, number = {2}, publisher = {John Wiley \& Sons, Inc.}, address = {Hoboken}, issn = {1466-822X}, doi = {10.1111/geb.13018}, pages = {198 -- 206}, year = {2019}, abstract = {Issue Despite their rather similar climatic conditions, eastern Eurasia and northern North America are largely covered by different plant functional types (deciduous or evergreen boreal forest) composed of larch or pine, spruce and fir, respectively. I propose that these deciduous and evergreen boreal forests represent alternative quasi-stable states, triggered by their different northern tree refugia that reflect the different environmental conditions experienced during the Last Glacial. Evidence This view is supported by palaeoecological and environmental evidence. Once established, Asian larch forests are likely to have stabilized through a complex vegetation-fire-permafrost soil-climate feedback system. Conclusion With respect to future forest developments, this implies that Asian larch forests are likely to be governed by long-term trajectories and are therefore largely resistant to natural climate variability on time-scales shorter than millennia. The effects of regional human impact and anthropogenic global warming might, however, cause certain stability thresholds to be crossed, meaning that irreversible transitions occur and resulting in marked consequences for ecosystem services on these human-relevant time-scales.}, language = {en} } @article{Roos2019, author = {Roos, Saskia}, title = {The Dirac operator under collapse to a smooth limit space}, series = {Annals of global analysis and geometry}, volume = {57}, journal = {Annals of global analysis and geometry}, number = {1}, publisher = {Springer}, address = {Dordrecht}, issn = {0232-704X}, doi = {10.1007/s10455-019-09691-8}, pages = {121 -- 151}, year = {2019}, abstract = {Let (M-i, g(i))(i is an element of N) be a sequence of spin manifolds with uniform bounded curvature and diameter that converges to a lower-dimensional Riemannian manifold (B, h) in the Gromov-Hausdorff topology. Then, it happens that the spectrum of the Dirac operator converges to the spectrum of a certain first-order elliptic differential operator D-B on B. We give an explicit description of D-B and characterize the special case where D-B equals the Dirac operator on B.}, language = {en} } @article{EngelsMedeirosAxfordetal.2020, author = {Engels, Stefan and Medeiros, Andrew S. and Axford, Yarrow and Brooks, Steve and Heiri, Oliver and Luoto, Tomi P. and Nazarova, Larisa B. and Porinchu, David F. and Quinlan, Roberto and Self, Angela E.}, title = {Temperature change as a driver of spatial patterns and long-term trends in chironomid (Insecta: Diptera) diversity}, series = {Global change biology}, volume = {26}, journal = {Global change biology}, number = {3}, publisher = {Wiley}, address = {Hoboken}, issn = {1354-1013}, doi = {10.1111/gcb.14862}, pages = {1155 -- 1169}, year = {2020}, abstract = {Anthropogenic activities have led to a global decline in biodiversity, and monitoring studies indicate that both insect communities and wetland ecosystems are particularly affected. However, there is a need for long-term data (over centennial or millennial timescales) to better understand natural community dynamics and the processes that govern the observed trends. Chironomids (Insecta: Diptera: Chironomidae) are often the most abundant insects in lake ecosystems, sensitive to environmental change, and, because their larval exoskeleton head capsules preserve well in lake sediments, they provide a unique record of insect community dynamics through time. Here, we provide the results of a metadata analysis of chironomid diversity across a range of spatial and temporal scales. First, we analyse spatial trends in chironomid diversity using Northern Hemispheric data sets overall consisting of 837 lakes. Our results indicate that in most of our data sets, summer temperature (T-jul) is strongly associated with spatial trends in modern-day chironomid diversity. We observe a strong increase in chironomid alpha diversity with increasing T-jul in regions with present-day T-jul between 2.5 and 14 degrees C. In some areas with T-jul > 14 degrees C, chironomid diversity stabilizes or declines. Second, we demonstrate that the direction and amplitude of change in alpha diversity in a compilation of subfossil chironomid records spanning the last glacial-interglacial transition (similar to 15,000-11,000 years ago) are similar to those observed in our modern data. A compilation of Holocene records shows that during phases when the amplitude of temperature change was small, site-specific factors had a greater influence on the chironomid fauna obscuring the chironomid diversity-temperature relationship. Our results imply expected overall chironomid diversity increases in colder regions such as the Arctic under sustained global warming, but with complex and not necessarily predictable responses for individual sites.}, language = {en} } @article{Daviter2017, author = {Daviter, Falk}, title = {Policy analysis in the face of complexity}, series = {Public policy and administration}, volume = {34}, journal = {Public policy and administration}, number = {1}, publisher = {Sage Publ.}, address = {London}, issn = {0952-0767}, doi = {10.1177/0952076717733325}, pages = {21}, year = {2017}, abstract = {An ever-increasing number of policy problems have come to be interpreted as representing a particular type of intractable, ill-structured or wicked policy problem. Much of this debate is concerned with the challenges wicked problems pose for program management rather than policy analysis. This article, in contrast, argues that the key challenge in addressing this type of policy problems is in fact analytical. Wicked policy problems are difficult to identify and interpret. The knowledge base for analysing wicked policy problem is typically fragmented and contested. Available evidence is incomplete, inconclusive and incommensurable. In this situation, the evidentiary and the interpretative elements of policy analysis become increasingly indistinguishable and inseparably intertwined. The article reveals the problems this poses for policy analysis and explores the extent to which the consolidation, consensualization and contestation of evidence in policy analysis offer alternative procedural paths to resolve these problems.}, language = {en} } @misc{PonceSchererBoekstegersetal.2019, author = {Ponce, Carol Barahona and Scherer, Dominique and Boekstegers, Felix and Garate-Calderon, Valentina and Jenab, Mazda and Aleksandrova, Krasimira and Katzke, Verena and Weiderpass, Elisabete and Bonet, Catalina and Moradi, Tahereh and Fischer, Krista and Bossers, Willem and Brenner, Hermann and Sch{\"o}ttker, Ben and Holleczek, Bernd and Hveem, Kristian and Eklund, Niina and Voelker, Uwe and Waldenberger, Melanie and Bermejo, Justo Lorenzo}, title = {Arsenic and gallbladder cancer risk}, series = {International journal of cancer}, volume = {146}, journal = {International journal of cancer}, number = {9}, publisher = {Wiley}, address = {Hoboken}, issn = {0020-7136}, doi = {10.1002/ijc.32837}, pages = {2648 -- 2650}, year = {2019}, language = {en} } @article{SublettSendulaLamadridetal.2019, author = {Sublett, David Matthew and Sendula, Eszter and Lamadrid, Hector and Steele-MacInnis, Matthew and Spiekermann, Georg and Burruss, Robert C. and Bodnar, Robert J.}, title = {Shift in the Raman symmetric stretching band of N-2, CO2, and CH4 as a function of temperature, pressure, and density}, series = {Journal of Raman spectroscopy : JRS}, volume = {51}, journal = {Journal of Raman spectroscopy : JRS}, number = {3}, publisher = {Wiley}, address = {Hoboken}, issn = {0377-0486}, doi = {10.1002/jrs.5805}, pages = {555 -- 568}, year = {2019}, abstract = {The Raman spectra of pure N-2, CO2, and CH4 were analyzed over the range 10 to 500 bars and from -160 degrees C to 200 degrees C (N-2), 22 degrees C to 350 degrees C (CO2), and -100 degrees C to 450 degrees C (CH4). At constant temperature, Raman peak position, including the more intense CO2 peak (nu+), decreases (shifts to lower wave number) with increasing pressure for all three gases over the entire pressure and temperature (PT) range studied. At constant pressure, the peak position for CO2 and CH4 increases (shifts to higher wave number) with increasing temperature over the entire PT range studied. In contrast, N-2 first shows an increase in peak position with increasing temperature at constant pressure, followed by a decrease in peak position with increasing temperature. The inflection temperature at which the trend reverses for N-2 is located between 0 degrees C and 50 degrees C at pressures above similar to 50 bars and is pressure dependent. Below similar to 50 bars, the inflection temperature was observed as low as -120 degrees C. The shifts in Raman peak positions with PT are related to relative density changes, which reflect changes in intermolecular attraction and repulsion. A conceptual model relating the Raman spectral properties of N-2, CO2, and CH4 to relative density (volume) changes and attractive and repulsive forces is presented here. Additionally, reduced temperature-dependent densimeters and barometers are presented for each pure component over the respective PT ranges. The Raman spectral behavior of the pure gases as a function of temperature and pressure is assessed to provide a framework for understanding the behavior of each component in multicomponent N-2-CO2-CH4 gas systems in a future study.}, language = {en} } @article{StonesTurner2020, author = {Stones, Rob and Turner, Bryan S.}, title = {Successful societies}, series = {The British journal of sociology : BJS online}, volume = {71}, journal = {The British journal of sociology : BJS online}, number = {1}, publisher = {Wiley}, address = {Hoboken}, issn = {0007-1315}, doi = {10.1111/1468-4446.12724}, pages = {183 -- 199}, year = {2020}, abstract = {Combining moral philosophy with sociological theory to build on themes introduced in Hall and Lamont's Successful Societies (2009), the paper outlines a distinctive perspective. It holds that a necessary condition of successful societies is that decision-makers base their decisions on a high level of attentiveness (concern and comprehension) towards subjectively valued and morally legitimate forms of life. Late modern societies consist of a plurality of forms of life, each providing grounds for what Alasdair MacIntyre has called internal goods—valued and morally valuable practices. The status of such goods is examined, and distinctions are drawn between their manifest and latent, and transposable and situationally specific, characteristics. We integrate this refined idea of internal goods into a developed conception of habitus that is both morally informed and situationally embedded. The sociological approach of strong structuration theory (SST) is employed to demonstrate how this conception of habitus can guide the critique of decision-making that damages internal goods. We identify the most pervasive and invidious forms of damaging decision-making in contemporary societies as those involving excessive forms of instrumental reasoning. We argue that our developed conception of habitus, anchored in the collectively valued practices of specific worlds, can be a powerful focus for resistance. Accounts of scholarship in higher education and of the white working class in America illustrate the specificities of singular, particular, social worlds and illuminate critical challenges raised by the perspective we advocate.}, language = {en} } @misc{Franzke2019, author = {Franzke, Jochen}, title = {Rezension zu: The Routledge handbook of international local government / edited by Richard Kerley, Joyce Liddle and Pamela T. Dunning. - London: Routledge, 2018. - 528 pp. - ISBN: 978- 11-3823-472-7, ISBN: 978-1-31530-627-8}, series = {Local government studies}, volume = {46}, journal = {Local government studies}, number = {1}, publisher = {Routledge}, address = {Abingdon}, issn = {0300-3930}, doi = {10.1080/03003930.2020.1702771}, pages = {163 -- 165}, year = {2019}, abstract = {When I took up the task of writing a review of the Routledge handbook of international local government, it occurred to me, as a member of the generation of the 1950s, that I had not even considered whether such compendiums were even necessary in times of easy internet searching. This review will look at whether that is indeed the case. Social-science handbooks naturally are very broad. This also applies to the particular handbook under review. It comprises six content-thematic parts with 33 chapters by 73 authors from 21 countries, with the UK and USA dominant. The focal points, discussed in more detail below, are local elections and local governance, local governments in different jurisdictions, the challenges of local government services, citizen engagement in local affairs, and local authorities in multi-level finance systems that shape how municipal governments 'get and spend' public money. These are exactly the topics actually discussed in the international community of political scientists. As a preliminary, the editors work out the theoretical-methodological foundations of the topic. They define 'the local' as 'geographically defined sub-national state administrative or political divisions' (p. 3). As next steps, they analyse the difference between government and governance, and investigate whether local government is globally important and relevant. Fortunately, they conclude that this is indeed the case. Part I of the handbook illustrates 'substantive variations' in the local electoral systems and 'notable divergences in the values and assumptions of local governance among democratic countries' (p. 23). That topic is indeed central to local authorities' legitimacy in democratic political systems. The focus of this part of the handbook is on current research and debates around local electoral systems, the challenges of local political leadership and the councillor's role in modern local policy. Current trends at the local level are analysed from the actors' perspectives or from an economic point of view by comparing institutionalised differences in city managers, mayors and council members across different jurisdictions. Sections that investigate traditional leadership and local government in Pacific Island countries are of particular interest to most Western readers, because in Europe and North America we know too little about such issues in that part of the world. Part II of the handbook presents current development processes and challenges in various local government systems. The chapters are territorially oriented around nation states or sub-national regions. This part of the handbook deal with local government in the Pacific Islands, Latin America, and New Zealand and in the Caribbean. However, the rationale behind country selection is not always clear; important countries like China, India and Nigeria, just to name a few, are absent. Unfortunately, there is no summary article highlighting similarities and differences, as well as the challenges in local government, relating to the countries studied in the book. The development of local services is the focus of Part III of the handbook, however, the definition of local services remains highly controversial and their scope varies widely between the countries. From the 1980s onwards, there was a long-term trend towards the marketisation and economisation of local politics, but since the turn of the millennium, there has been a counter-trend of the return of municipalities and third sector in the fields of local public services (Wollmann 2018). The book analyses the US and Georgia as case studies for development trends, finding that local government entrepreneurship remains an important factor in promoting economic development and strengthening capacities. I was pleased to see that Part IV, the next and most extensive part of the handbook, deals with citizen engagement, because the future of local self-government across the world depends not only on top down activities by local governing elites, but above all on the commitment of the inhabitants of cities and municipalities. Practices and challenges of citizen participation in local government are analysed in inspiring case studies of mid-sized cities in Russia and the United States. The contribution on urban governance of austerity in Europe is also of particular interest. The 2008 global financial crash and the subsequent severe budgetary pressure on municipalities in many countries was a key event in the history and development of local self-government, confronting municipalities with 'the harsh realities of political economy' (p. 293). Several articles analyse the causes of the declining confidence of the citizens in local authorities in some countries. In contrast, the open budget tool in Brazil is as a positive example of collaborative stakeholder engagement. Part V deals with multi-level governance. With the exception of Australia, it is all about Europe, especially the role of municipalities in the EU's multilevel system. The authors conclude that 'local authorities are essential for executing EU legislation, and this turn allows them to shape EU policies' (p. 401). This part of the handbook includes the issue of local territorial reforms, which are central to local autonomy, combined with analyses of redesigning regional government and local-level Europeanisation. Subsequently, by comparing the local government systems of Southern Europe (France, Italy, Portugal and Spain), the authors underline convincingly the role of traditions, identity, legal frameworks and institutions in local government. Part VI of the book deals with the financial dimension of local self-government under the heading 'Getting and spending'. This is indeed the 'key source of dispute between local and central government' (p. 467) and the crucial factor shaping true local autonomy. Meritoriously, this part also contains a chapter on the fight against corruption and unethical behaviour by public servants. Based on research linking corruption to transparency and accountability, two case studies describe how Tbilisi (Georgia) and Lviv (Ukraine) try to reduce corruption in government budgeting and procurement. Enhancing Value-For-Money audit in local government highlights another important side of local finance. An interesting comparison reveals significant differences in local government revenues in European Union member states between 2000 and 2014. Of course, even in a 530-page book, some important aspects remain underexposed. Above all, I would have liked more attention on some of the enormous future challenges facing democratic systems and with them local governments all over the world, such as digitisation (e.g. in smart cities), the integration of migrants or climate change. The international networking of municipalities should also be given greater prominence. To sum it up, The Routledge Handbook on International Local Government is indeed 'ambitiously titled' as the editors underline. Yet, despite my critical objections about its focus on current issues rather than future challenges, they largely fulfil this promise and their general approach has worked well. Across continents and political-administrative cultures, illustrated with many new research findings, they have created an outstanding publication focusing on the challenges and policy of local self-governmental authorities and other local stakeholders. There is a good chance that this handbook will belong in future to the social science standard works on local issues, and be included in academic political science teaching. May the publisher's wish come true; that this book stimulates its readers to develop further research ideas. Finally, I come back to my initial question. 'Old fashioned' printed handbooks like these continue to make sense, even in modern digital times.}, language = {en} } @article{VoigtSchollBaueretal.2020, author = {Voigt, Christian and Scholl, Julia M. and Bauer, Juliane and Teige, Tobias and Yovel, Yossi and Kramer-Schadt, Stephanie and Gras, Pierre}, title = {Movement responses of common noctule bats to the illuminated urban landscape}, series = {Landscape ecology}, volume = {35}, journal = {Landscape ecology}, number = {1}, publisher = {Springer}, address = {Dordrecht}, issn = {0921-2973}, doi = {10.1007/s10980-019-00942-4}, pages = {189 -- 201}, year = {2020}, abstract = {Context Cities are a challenging habitat for obligate nocturnal mammals because of the ubiquitous use of artificial light at night (ALAN). How nocturnal animals move in an urban landscape, particularly in response to ALAN is largely unknown. Objectives We studied the movement responses, foraging and commuting, of common noctules (Nyctalus noctula) to urban landscape features in general and ALAN in particular. Methods We equipped 20 bats with miniaturized GPS loggers in the Berlin metropolitan area and related spatial positions of bats to anthropogenic and natural landscape features and levels of ALAN. Results Common noctules foraged close to ALAN only next to bodies of water or well vegetated areas, probably to exploit swarms of insects lured by street lights. In contrast, they avoided illuminated roads, irrespective of vegetation cover nearby. Predictive maps identified most of the metropolitan area as non-favoured by this species because of high levels of impervious surfaces and ALAN. Dark corridors were used by common noctules for commuting and thus likely improved the permeability of the city landscape. Conclusions We conclude that the spatial use of common noctules, previously considered to be more tolerant to light than other bats, is largely constrained by ALAN. Our study is the first individual-based GPS tracking study to show sensitive responses of nocturnal wildlife to light pollution. Approaches to protect urban biodiversity need to include ALAN to safeguard the larger network of dark habitats for bats and other nocturnal species in cities.}, language = {en} } @article{FiedlerHainzlZoelleretal.2018, author = {Fiedler, Bernhard and Hainzl, Sebastian and Z{\"o}ller, Gert and Holschneider, Matthias}, title = {Detection of Gutenberg-Richter b-Value Changes in Earthquake Time Series}, series = {Bulletin of the Seismological Society of America}, volume = {108}, journal = {Bulletin of the Seismological Society of America}, number = {5A}, publisher = {Seismological Society of America}, address = {Albany}, issn = {0037-1106}, doi = {10.1785/0120180091}, pages = {2778 -- 2787}, year = {2018}, abstract = {The Gutenberg-Richter relation for earthquake magnitudes is the most famous empirical law in seismology. It states that the frequency of earthquake magnitudes follows an exponential distribution; this has been found to be a robust feature of seismicity above the completeness magnitude, and it is independent of whether global, regional, or local seismicity is analyzed. However, the exponent b of the distribution varies significantly in space and time, which is important for process understanding and seismic hazard assessment; this is particularly true because of the fact that the Gutenberg-Richter b-value acts as a proxy for the stress state and quantifies the ratio of large-to-small earthquakes. In our work, we focus on the automatic detection of statistically significant temporal changes of the b-value in seismicity data. In our approach, we use Bayes factors for model selection and estimate multiple change-points of the frequency-magnitude distribution in time. The method is first applied to synthetic data, showing its capability to detect change-points as function of the size of the sample and the b-value contrast. Finally, we apply this approach to examples of observational data sets for which b-value changes have previously been stated. Our analysis of foreshock and after-shock sequences related to mainshocks, as well as earthquake swarms, shows that only a portion of the b-value changes is statistically significant.}, language = {en} } @article{TapeJonesArpetal.2018, author = {Tape, Ken D. and Jones, Benjamin M. and Arp, Christopher D. and Nitze, Ingmar and Grosse, Guido}, title = {Tundra be dammed}, series = {Global change biology}, volume = {24}, journal = {Global change biology}, number = {10}, publisher = {Wiley}, address = {Hoboken}, issn = {1354-1013}, doi = {10.1111/gcb.14332}, pages = {4478 -- 4488}, year = {2018}, abstract = {Increasing air temperatures are changing the arctic tundra biome. Permafrost is thawing, snow duration is decreasing, shrub vegetation is proliferating, and boreal wildlife is encroaching. Here we present evidence of the recent range expansion of North American beaver (Castor canadensis) into the Arctic, and consider how this ecosystem engineer might reshape the landscape, biodiversity, and ecosystem processes. We developed a remote sensing approach that maps formation and disappearance of ponds associated with beaver activity. Since 1999, 56 new beaver pond complexes were identified, indicating that beavers are colonizing a predominantly tundra region (18,293km(2)) of northwest Alaska. It is unclear how improved tundra stream habitat, population rebound following overtrapping for furs, or other factors are contributing to beaver range expansion. We discuss rates and likely routes of tundra beaver colonization, as well as effects on permafrost, stream ice regimes, and freshwater and riparian habitat. Beaver ponds and associated hydrologic changes are thawing permafrost. Pond formation increases winter water temperatures in the pond and downstream, likely creating new and more varied aquatic habitat, but specific biological implications are unknown. Beavers create dynamic wetlands and are agents of disturbance that may enhance ecosystem responses to warming in the Arctic.}, language = {en} } @article{KoehlerKoehlerDeckwartetal.2018, author = {Koehler, Friedrich and Koehler, Kerstin and Deckwart, Oliver and Prescher, Sandra and Wegscheider, Karl and Winkler, Sebastian and Vettorazzi, Eik and Polze, Andreas and Stangl, Karl and Hartmann, Oliver and Marx, Almuth and Neuhaus, Petra and Scherf, Michael and Kirwan, Bridget-Anne and Anker, Stefan D.}, title = {Telemedical Interventional Management in Heart Failure II (TIM-HF2), a randomised, controlled trial investigating the impact of telemedicine on unplanned cardiovascular hospitalisations and mortality in heart failure patients}, series = {European Journal of Heart Failure}, volume = {20}, journal = {European Journal of Heart Failure}, number = {10}, publisher = {Wiley}, address = {Hoboken}, issn = {1388-9842}, doi = {10.1002/ejhf.1300}, pages = {1485 -- 1493}, year = {2018}, abstract = {Background Heart failure (HF) is a complex, chronic condition that is associated with debilitating symptoms, all of which necessitate close follow-up by health care providers. Lack of disease monitoring may result in increased mortality and more frequent hospital readmissions for decompensated HF. Remote patient management (RPM) in this patient population may help to detect early signs and symptoms of cardiac decompensation, thus enabling a prompt initiation of the appropriate treatment and care before a manifestation of HF decompensation. Objective The objective of the present article is to describe the design of a new trial investigating the impact of RPM on unplanned cardiovascular hospitalisations and mortality in HF patients. Methods The TIM-HF2 trial is designed as a prospective, randomised, controlled, parallel group, open (with randomisation concealment), multicentre trial with pragmatic elements introduced for data collection. Eligible patients with HF are randomised (1:1) to either RPM + usual care or to usual care only and are followed for 12 months. The primary outcome is the percentage of days lost due to unplanned cardiovascular hospitalisations or all-cause death. The main secondary outcomes are all-cause and cardiovascular mortality. Conclusion The TIM-HF2 trial will provide important prospective data on the potential beneficial effect of telemedical monitoring and RPM on unplanned cardiovascular hospitalisations and mortality in HF patients.}, language = {en} } @article{FrancoObregonCambriaGreutertetal.2018, author = {Franco-Obregon, Alfredo and Cambria, Elena and Greutert, Helen and Wernas, Timon and Hitzl, Wolfgang and Egli, Marcel and Sekiguchi, Miho and Boos, Norbert and Hausmann, Oliver and Ferguson, Stephen J. and Kobayashi, Hiroshi and W{\"u}rtz-Kozak, Karin}, title = {TRPC6 in simulated microgravity of intervertebral disc cells}, series = {European Spine Journal}, volume = {27}, journal = {European Spine Journal}, number = {10}, publisher = {Springer}, address = {New York}, issn = {0940-6719}, doi = {10.1007/s00586-018-5688-8}, pages = {2621 -- 2630}, year = {2018}, abstract = {Purpose Prolonged bed rest and microgravity in space cause intervertebral disc (IVD) degeneration. However, the underlying molecular mechanisms are not completely understood. Transient receptor potential canonical (TRPC) channels are implicated in mechanosensing of several tissues, but are poorly explored in IVDs. Methods Primary human IVD cells from surgical biopsies composed of both annulus fibrosus and nucleus pulposus (passage 1-2) were exposed to simulated microgravity and to the TRPC channel inhibitor SKF-96365 (SKF) for up to 5days. Proliferative capacity, cell cycle distribution, senescence and TRPC channel expression were analyzed. Results Both simulated microgravity and TRPC channel antagonism reduced the proliferative capacity of IVD cells and induced senescence. While significant changes in cell cycle distributions (reduction in G1 and accumulation in G2/M) were observed upon SKF treatment, the effect was small upon 3days of simulated microgravity. Finally, downregulation of TRPC6 was shown under simulated microgravity. Conclusions Simulated microgravity and TRPC channel inhibition both led to reduced proliferation and increased senescence. Furthermore, simulated microgravity reduced TRPC6 expression. IVD cell senescence and mechanotransduction may hence potentially be regulated by TRPC6 expression. This study thus reveals promising targets for future studies.}, language = {en} } @article{HoffmannCortesGarciaWarschburger2018, author = {Hoffmann, Svenja Sarah Helen and Cortes-Garcia, Laura and Warschburger, Petra}, title = {Weight/shape and muscularity concerns and emotional problems in adolescent boys and girls}, series = {Journal of adolescence}, volume = {68}, journal = {Journal of adolescence}, publisher = {Elsevier}, address = {London}, issn = {0140-1971}, doi = {10.1016/j.adolescence.2018.07.005}, pages = {70 -- 77}, year = {2018}, abstract = {Introduction: The goal of the present study was to identify the prospective relations between weight/shape and muscularity concerns and emotional problems in adolescents. Methods: Self-report data of 966 German male and female adolescents were analyzed in a cross lagged panel design. Results: Analyses of latent means revealed significant correlations between weight/shape concern and emotional problems as well as between muscularity concern and emotional problems in both genders. Moreover, weight/shape concern predicted emotional problems prospectively, but only in girls. Regarding muscularity concern, we could not find any prospective relation with emotional problems In boys or girls from the general population. Conclusions: It is assumed that as appearance is highly relevant for the self-concept in girls, concerns about the look might promote emotional problems. Thus, weight/shape concern should be addressed in the prevention of emotional problems in adolescent girls, whereas further research is necessary investigating the contribution of muscularity concern in this context.}, language = {en} } @misc{WarschburgerSproesserZahn2018, author = {Warschburger, Petra and Sproesser, Gudrun and Zahn, Daniela}, title = {Fachgruppe Gesundheitspsychologie: Methoden sind wichtig, Inhalte aber genauso}, series = {Psychologische Rundschau : offizielles Organ der Deutschen Gesellschaft f{\"u}r Psychologie}, volume = {69}, journal = {Psychologische Rundschau : offizielles Organ der Deutschen Gesellschaft f{\"u}r Psychologie}, number = {4}, publisher = {Hogrefe}, address = {G{\"o}ttingen}, issn = {0033-3042}, doi = {10.1026/0033-3042/a000418}, pages = {340 -- 341}, year = {2018}, language = {de} } @article{MurrayBraunReiners2018, author = {Murray, Kendra E. and Braun, Jean and Reiners, Peter W.}, title = {Toward Robust Interpretation of Low-Temperature Thermochronometers in Magmatic Terranes}, series = {Geochemistry, geophysics, geosystems}, volume = {19}, journal = {Geochemistry, geophysics, geosystems}, number = {10}, publisher = {American Geophysical Union}, address = {Washington}, issn = {1525-2027}, doi = {10.1029/2018GC007595}, pages = {3739 -- 3763}, year = {2018}, abstract = {Many regions central to our understanding of tectonics and landscape evolution are active or ancient magmatic terranes, and robust interpretation of low-temperature thermochronologic ages in these settings requires careful attention to the drivers of rock heating and cooling, including magmatism. However, we currently lack a quantitative framework for evaluating the potential role of magmatic coolingthat is, post-magmatic thermal relaxationin shaping cooling age patterns in regions with a history of intrusive magmatism. Here we use analytical approximations and numerical models to characterize how low-temperature thermochronometers document cooling inside and around plutons in steadily exhuming environments. Our models predict that the thermal field a pluton intrudes into, specifically the ambient temperatures relative to the closure temperature of a given thermochronometer, is as important as the pluton size and temperature in controlling the pattern and extent of thermochronometer resetting in the country rocks around a pluton. We identify one advective and several conductive timescales that govern the relationship between the crystallization and cooling ages inside a pluton. In synthetic vertical age-elevation relationships (AERs), resetting next to plutons results in changes in AER slope that could be misinterpreted as past changes in exhumation rate if the history of magmatism is not accounted for. Finally, we find that large midcrustal plutons, such as those emplaced at similar to 10-15-km depth, can reset the low-temperature thermochronometers far above them in the upper crusta result with considerable consequences for thermochronology in arcs and regions with a history of magmatic activity that may not have a surface expression.}, language = {en} } @article{SchmaelzlinMoralejoGersondeetal.2018, author = {Schm{\"a}lzlin, Elmar Gerd and Moralejo, Benito and Gersonde, Ingo and Schleusener, Johannes and Darvin, Maxim E. and Thiede, Gisela and Roth, Martin M.}, title = {Nonscanning large-area Raman imaging for ex vivo/in vivo skin cancer discrimination}, series = {Journal of biomedical optics}, volume = {23}, journal = {Journal of biomedical optics}, number = {10}, publisher = {SPIE}, address = {Bellingham}, issn = {1083-3668}, doi = {10.1117/1.JBO.23.10.105001}, pages = {11}, year = {2018}, abstract = {Imaging Raman spectroscopy can be used to identify cancerous tissue. Traditionally, a step-by-step scanning of the sample is applied to generate a Raman image, which, however, is too slow for routine examination of patients. By transferring the technique of integral field spectroscopy (IFS) from astronomy to Raman imaging, it becomes possible to record entire Raman images quickly within a single exposure, without the need for a tedious scanning procedure. An IFS-based Raman imaging setup is presented, which is capable of measuring skin ex vivo or in vivo. It is demonstrated how Raman images of healthy and cancerous skin biopsies were recorded and analyzed. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License.}, language = {en} } @article{MannRahmstorfKornhuberetal.2018, author = {Mann, Michael E. and Rahmstorf, Stefan and Kornhuber, Kai and Steinman, Byron A. and Miller, Sonya K. and Petri, Stefan and Coumou, Dim}, title = {Projected changes in persistent extreme summer weather events}, series = {Science Advances}, volume = {4}, journal = {Science Advances}, number = {10}, publisher = {American Assoc. for the Advancement of Science}, address = {Washington}, issn = {2375-2548}, doi = {10.1126/sciadv.aat3272}, pages = {9}, year = {2018}, abstract = {Persistent episodes of extreme weather in the Northern Hemisphere summer have been associated with high-amplitude quasi-stationary atmospheric Rossby waves, with zonal wave numbers 6 to 8 resulting from the phenomenon of quasi-resonant amplification (QRA). A fingerprint for the occurrence of QRA can be defined in terms of the zonally averaged surface temperature field. Examining state-of-the-art [Coupled Model Intercomparison Project Phase 5 (CMIP5)] climate model projections, we find that QRA events are likely to increase by similar to 50\% this century under business-as-usual carbon emissions, but there is considerable variation among climate models. Some predict a near tripling of QRA events by the end of the century, while others predict a potential decrease. Models with amplified Arctic warming yield the most pronounced increase in QRA events. The projections are strongly dependent on assumptions regarding the nature of changes in radiative forcing associated with anthropogenic aerosols over the next century. One implication of our findings is that a reduction in midlatitude aerosol loading could actually lead to Arctic de-amplification this century, ameliorating potential increases in persistent extreme weather events.}, language = {en} } @misc{Henze2018, author = {Henze, Andrea}, title = {Proteinoxidation als Indikator des Alterungsph{\"a}notyps und Target einer individualisierten Ern{\"a}hrungsintervention (ProAID)}, series = {Ern{\"a}hrungs-Umschau : Forschung \& Praxis}, volume = {65}, journal = {Ern{\"a}hrungs-Umschau : Forschung \& Praxis}, number = {10}, publisher = {Umschau-Zeitschriftenverl.}, address = {Frankfurt, Main}, issn = {0174-0008}, pages = {M566 -- M567}, year = {2018}, abstract = {Oxidative posttranslationale Modifikationen endogener Proteine werden v. a. durch reaktive Sauerstoff- und Stickstoffspezies (engl:. Reactive Oxygen Species, ROS, reactive nitrogen species, RNS) hervorgerufen und k{\"o}nnen sowohl reversibel (z. B. Disulfidbindungen) als auch irreversibel (z. B. Proteincarbonyle) erfolgen [1-3]. Lange wurde angenommen, dass oxidative posttranslationale Proteinmodifikationen (oxPTPM) nur von untergeordneter Bedeutung f{\"u}r den Metabolismus sind. Tats{\"a}chlich handelt es sich jedoch um einen physiologischen Prozess, der {\"u}ber die Modulation der Proteinstruktur auch die Proteinfunktion (z. B. Enzymaktivit{\"a}t, Stabilit{\"a}t) und somit zahlreiche Stoffwechselwege wie den Energiestoffwechsel, die Immunfunktion, die vaskul{\"a}re Funktion sowie Apoptose und Genexpression beeinflussen kann. Die Bildung von oxPTPM ist dabei hochreguliert und h{\"a}ngt u. a. von der Proteinstruktur, der Verf{\"u}gbarkeit von ROS und RNS sowie dem lokalen Mikromilieu der Zelle ab [2, 4].}, language = {de} } @misc{Kleuser2018, author = {Kleuser, Burkhard}, title = {The enigma of sphingolipids in health and disease}, series = {International journal of molecular sciences}, volume = {19}, journal = {International journal of molecular sciences}, number = {10}, publisher = {MDPI}, address = {Basel}, issn = {1422-0067}, doi = {10.3390/ijms19103126}, pages = {3}, year = {2018}, language = {en} } @article{SchotterLeinengervonderMalsburg2017, author = {Schotter, Elizabeth Roye and Leinenger, Mallorie and von der Malsburg, Titus Raban}, title = {When your mind skips what your eyes fixate}, series = {Psychonomic bulletin \& review : a journal of the Psychonomic Society}, volume = {25}, journal = {Psychonomic bulletin \& review : a journal of the Psychonomic Society}, number = {5}, publisher = {Springer}, address = {New York}, issn = {1069-9384}, doi = {10.3758/s13423-017-1356-y}, pages = {1884 -- 1890}, year = {2017}, abstract = {The phenomenon of forced fixations suggests that readers sometimes fixate a word (due to oculomotor constraints) even though they intended to skip it (due to parafoveal cognitive-linguistic processing). We investigate whether this leads readers to look directly at a word but not pay attention to it. We used a gaze-contingent boundary paradigm to dissociate parafoveal and foveal information (e.g., the word phone changed to scarf once the reader's eyes moved to it) and asked questions about the sentence to determine which one the reader encoded. When the word was skipped or fixated only briefly (i.e., up to 100 ms) readers were more likely to report reading the parafoveal than the fixated word, suggesting that there are cases in which readers look directly at a word but their minds ignore it, leading to the illusion of reading something they did not fixate.}, language = {en} } @article{WatheletGuillierRouxetal.2018, author = {Wathelet, Marc and Guillier, B. and Roux, P. and Cornou, C. and Ohrnberger, Matthias}, title = {Rayleigh wave three-component beamforming}, series = {Geophysical journal international}, volume = {215}, journal = {Geophysical journal international}, number = {1}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {0956-540X}, doi = {10.1093/gji/ggy286}, pages = {507 -- 523}, year = {2018}, abstract = {The variation of Rayleigh ellipticity versus frequency is gaining popularity in site characterization. It becomes a necessary observable to complement dispersion curves when inverting shear wave velocity profiles. Various methods have been proposed so far to extract polarization from ambient vibrations recorded on a single three-component station or with an array of three-component sensors. If only absolute values were recovered 10 yr ago, new array-based techniques were recently proposed with enhanced efficiencies providing also the ellipticity sign. With array processing, higher-order modes are often detected even in the ellipticity domain. We suggest to explore the properties of a high-resolution beamforming where radial and vertical components are explicitly included. If N is the number of three-component sensors, 2N x 2N cross-spectral density matrices are calculated for all presumed directions of propagation. They are built with N radial and N vertical channels. As a first approach, steering vectors are designed to fit with Rayleigh wave properties: the phase shift between radial and vertical components is either -Pi/2 or Pi/2. We show that neglecting the ellipticity tilt due to attenuation has only minor effects on the results. Additionally, we prove analytically that it is possible to retrieve the ellipticity value from the usual maximization of the high-resolution beam power. The method is tested on synthetic data sets and on experimental data. Both are reference sites already analysed by several authors. A detailed comparison with previous results on these cases is provided.}, language = {en} } @article{WengerLuedtkeBrunner2018, author = {Wenger, Marina and L{\"u}dtke, Oliver and Brunner, Martin}, title = {{\"U}bereinstimmung, Variabilit{\"a}t und Reliabilit{\"a}t von Sch{\"u}lerurteilen zur Unterrichtsqualit{\"a}t auf Schulebene}, series = {Zeitschrift f{\"u}r Erziehungswissenschaft}, volume = {21}, journal = {Zeitschrift f{\"u}r Erziehungswissenschaft}, number = {5}, publisher = {Springer}, address = {Wiesbaden}, issn = {1434-663X}, doi = {10.1007/s11618-018-0813-3}, pages = {929 -- 950}, year = {2018}, abstract = {F{\"u}r die Analyse der Unterrichtsqualit{\"a}t von Schulen durch Sch{\"u}lerurteile sollten drei Voraussetzungen erf{\"u}llt sein: (1) eine angemessene {\"U}bereinstimmung der Sch{\"u}lerurteile innerhalb der Schulen, (2) systematische Variabilit{\"a}t der Sch{\"u}lerurteile zwischen Schulen, (3) ein ausreichendes Maß an Reliabilit{\"a}t der aggregierten Urteile. Diese Studie untersucht mit internationalen PISA-Daten (Zyklen 2000-2012; 81 L{\"a}nder, {\"u}ber 55.300 Schulen, {\"u}ber 1,3 Millionen 15-J{\"a}hrige), inwiefern dies f{\"u}r Indikatoren der Qualit{\"a}tsdimensionen des Unterrichts (Klassenf{\"u}hrung, Kognitive Aktivierung, Konstruktive Unterst{\"u}tzung) zutrifft. Daf{\"u}r bestimmten wir das {\"U}bereinstimmungsmaß rWG(J) sowie die Intraklassenkorrelationen ICC(1) und ICC(2). Es zeigte sich, dass (1) die Mehrzahl der Unterrichtsmerkmale eine moderate oder starke {\"U}bereinstimmung in Schulen aufwies, (2) sich Unterrichtsmerkmale aus Sicht der Sch{\"u}lerschaft systematisch zwischen Schulen unterschieden, jedoch (3) die Reliabilit{\"a}t der aggregierten Sch{\"u}lerurteile in vielen L{\"a}ndern nicht ausreichte. Die Ergebnisse diskutieren wir vor dem Hintergrund von Konventionen zur Beurteilung der {\"U}bereinstimmung, Variabilit{\"a}t und Reliabilit{\"a}t auf Schulebene.}, language = {de} }