@misc{KochLaschewskyRingsdorfetal.1986, author = {Koch, Horst and Laschewsky, Andr{\´e} and Ringsdorf, Helmut and Teng, Kang}, title = {Photodimerization and photopolymerization of amphiphilic cinnamic acid derivatives in oriented monolayers, vesicles and solution}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-17111}, year = {1986}, abstract = {Cinnamic acid moieties were incorporated into amphiphilic compounds containing one and two alkyl chains. These lipid-like compounds with photoreactive units undergo self-organization to form monolayers at the gas-water interface and bilayer structures (vesicles) in aqueous solutions. The photoreaction of the cinnamic acid moiety induced by 254 nm UV light was investigated in the crystalline state, in monolayers, in vesicles and in solution in organic solvents. The single-chain amphiphiles undergo dimerization to yield photoproducts with twice the molecular weight of the corresponding monomers in organized systems. The photoreaction of amphiphiles containing two cinnamic acid groups occurs via two mechanisms: The intramolecular dimerization produces bicycles, with retention of the molecular weight of the corresponding monomer. The intermolecular reaction leads to oligomeric and polymeric photoproducts. In contrast to the single-chain amphiphiles, photodimerization processes of lipoids containing two cinnamic acid moieties also occur in solution in organic solvents.}, language = {en} } @misc{AlbrechtCummingKreuderetal.1986, author = {Albrecht, O. and Cumming, W. and Kreuder, W. and Laschewsky, Andr{\´e} and Ringsdorf, Helmut}, title = {Monolayers of rod-shaped and disc-shaped liquid crystalline compounds at the air-water interface}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-17124}, year = {1986}, abstract = {Calamitic (rod-shaped) and discotic (disc-shaped) thermotropic liquid crystalline (LC) compounds were spread at the air-water interface, and their ability to form monolayers was studied. The calamitic LCs investigated were found to form monolayers which behave analogously to conventional amphiphiles such as fatty acids. The spreading of the discotic LCs produced monolayers as well, but with a behaviour different from classical amphiphiles. The areas occupied per molecule are too small to allow the contact of all hydrophilic groups with the water surface and the packing of all hydrophobic chains. Various molecular arrangements of the discotics at the water surface to fit the spreading data are discussed.}, language = {en} } @misc{KortPeterKoopmanschap1983, author = {Kort, C. A. D. de and Peter, Martin G. and Koopmanschap, A. B.}, title = {Binding and degradation of juvenile hormone III by haemolymph proteins of the Colorado potato beetle: a re-examination}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-16777}, year = {1983}, abstract = {The haemolymph of the adult Colorado potato beetle, Lepinotarsa decemlineata Say, contains a high molecular weight (MW > 200,000) JH-III specific binding protein. The Kd value of the protein for racemic JH-III is 1.3 ± 0.2 × 10-7 M. It has a lower affinity for racemic JH-I and it does not bind JH-III-diol or JH-III-acid. The binding protein does discriminate between the enantiomers of synthetic, racemic JH-III as was determined by stereochemical anaysis of the bound and the free JH-III. Incubation of racemic JH-III with crude haemolymph results in preferential formation of (10S)-JH-III-acid, the unnatural configuration. The JH-esterase present in L. decemlineata haemolymph is not enantioselective. It is concluded that the most important function of the binding protein is that of a specific carrier, protecting the natural hormone against degradation by esterases. The carrier does not protect JH-I as efficiently as the lower homologue.}, language = {en} } @misc{FrimmelKumke1998, author = {Frimmel, Fritz Hartmann and Kumke, Michael Uwe}, title = {Optische Parameter zur Stoffcharakterisierung vom Trinkwasser bis zum Abwasser}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-13088}, year = {1998}, abstract = {Die Anwendung von optischen Parametern zur Stoffcharakterisierung wird diskutiert. Dabei ist der Schwerpunkt der Diskussion auf absorptions- und fluoreszenzspektroskopische Methoden gesetzt. Beide Methoden k{\"o}nnen schnell und zuverl{\"a}ssig - auch im on-line Betrieb - eingesetzt werden. Der Beitrag soll einen {\"U}berblick {\"u}ber die grundlegenden M{\"o}glichkeiten der Anwendung beider Methoden geben.}, language = {de} } @misc{LoehmannsroebenBeckHildebrandtetal.2006, author = {L{\"o}hmannsr{\"o}ben, Hans-Gerd and Beck, Michael and Hildebrandt, Niko and Schm{\"a}lzlin, Elmar and van Dongen, Joost T.}, title = {New challenges in biophotonics : laser-based fluoroimmuno analysis and in-vivo optical oxygen monitoring}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-10120}, year = {2006}, abstract = {Two examples of our biophotonic research utilizing nanoparticles are presented, namely laser-based fluoroimmuno analysis and in-vivo optical oxygen monitoring. Results of the work include significantly enhanced sensitivity of a homogeneous fluorescence immunoassay and markedly improved spatial resolution of oxygen gradients in root nodules of a legume species.}, subject = {Sauerstoff}, language = {en} } @misc{NiederkruegerSalbBecketal.2006, author = {Niederkr{\"u}ger, Matthias and Salb, Christian and Beck, Michael and Hildebrandt, Niko and L{\"o}hmannsr{\"o}ben, Hans-Gerd and Marowsky, Gerd}, title = {Improvement of a fluorescence immunoassay with a compact diode-pumped solid state laser at 315 nm}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-10150}, year = {2006}, abstract = {We demonstrate the improvement of fluorescence immunoassay (FIA) diagnostics in deploying a newly developed compact diode-pumped solid state (DPSS) laser with emission at 315 nm. The laser is based on the quasi-three-level transition in Nd:YAG at 946 nm. The pulsed operation is either realized by an active Q-switch using an electro-optical device or by introduction of a Cr4+:YAG saturable absorber as passive Q-switch element. By extra-cavity second harmonic generation in different nonlinear crystal media we obtained blue light at 473 nm. Subsequent mixing of the fundamental and the second harmonic in a β-barium-borate crystal provided pulsed emission at 315 nm with up to 20 μJ maximum pulse energy and 17 ns pulse duration. Substitution of a nitrogen laser in a FIA diagnostics system by the DPSS laser succeeded in considerable improvement of the detection limit. Despite significantly lower pulse energies (7 μJ DPSS laser versus 150 μJ nitrogen laser), in preliminary investigations the limit of detection was reduced by a factor of three for a typical FIA.}, subject = {Immunoassay}, language = {en} } @misc{KaafaraniWexStrehmeletal.2002, author = {Kaafarani, Bilal R. and Wex, Brigitte and Strehmel, Bernd and Neckers, Douglas C.}, title = {Structural concept for fluorinated Y-enynes with solvatochromic properties}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-13168}, year = {2002}, abstract = {An approach to the development of fluorescent probes to follow polymerizations in situ using fluorinated cross-conjugated enediynes (Y-enynes) is reported. Different substitution patterns in the Y-enynes result in distinct solvatochromic behavior. β,β-Bis(phenylethynyl)pentafluorostyrene 7, which bears no donor substituents and only fluorine at the styrene moiety, shows no solvatochromism. Donor substituted β,β-bis(3,4,5-trimethoxyphenylethynyl) pentafluorostyrene 8 and β,β-bis(4-butyl-2,3,5,6-tetrafluorophenylethynyl)-3,4,5-trimethoxystyrene 9 exhibit solvatochromism upon change of solvent polarity. Y-enyne 8 showed the largest solvatochromic shift (94 nm bathochromic shift) upon changing solvent from cyclohexane to acetonitrile. A smaller solvatochromic response (44 nm bathochromic shift) was observed for 9. Lippert-Mataga treatment of 8 and 9 yields slopes of -10,800 and -6,400 cm -1, respectively. This corresponds to a change in dipole moment of 9.6 and 6.9 D, respectively. The solvatochromic behavior in 8 and 9 supports the formation of an intramolecular charge transfer (ICT) state. The low fluorescence quantum yields are caused by competitive double bond rotation. The fluorescence decay time of 9 decreases in methyltetrahydrofuran from 2.1 ns at 77 K to 0.11 ns at 200 K. Efficient single bond rotation in 9 was frozen at -50 °C in a configuration in which the trimethoxyphenyl ring is perpendicular to the fluorinated rings. 7-9 are photostable compounds. The X-ray structure of 7 shows it is not planar and that its conjugation is distorted. Y-enyne 7 stacks in the solid state showing coulombic, actetylene-arene, and fluorine-π interactions.}, language = {en} } @misc{ReichLoehmannsroebenSchael2003, author = {Reich, Oliver and L{\"o}hmannsr{\"o}ben, Hans-Gerd and Schael, Frank}, title = {Optical sensing with photon density waves: investigation of model media}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-13147}, year = {2003}, abstract = {Investigations with frequency domain photon density waves allow elucidation of absorption and scattering properties of turbid media. The temporal and spatial propagation of intensity modulated light with frequencies up to more than 1 GHz can be described by the P1 approximation to the Boltzmann transport equation. In this study, we establish requirements for the appropriate choice of turbid model media and characterize mixtures of isosulfan blue as absorber and polystyrene beads as scatterer. For these model media, the independent determination of absorption and reduced scattering coefficients over large absorber and scatterer concentration ranges is demonstrated with a frequency domain photon density wave spectrometer employing intensity and phase measurements at various modulation frequencies.}, language = {en} } @misc{LoehmannsroebenKantorKumkeetal.2005, author = {L{\"o}hmannsr{\"o}ben, Hans-Gerd and Kantor, Zoltan and Kumke, Michael Uwe and Schm{\"a}lzlin, Elmar and Reich, Oliver}, title = {OPQS - optische Prozess- und Qualit{\"a}ts-Sensorik}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-13205}, year = {2005}, abstract = {Im vorliegenden Beitrag wird an Hand dreier Beispiele der Einsatz von optischer Sensorik zur Produktcharakterisierung dargestellt, n{\"a}mlich Untersuchungen zum O2-Gehalt in Fruchts{\"a}ften, zur Isotopiesignatur von CO2 in Mineralw{\"a}ssern und zu Lichtstreueigenschaften eines Sonnenschutzmittels. Inhalt: Bestimmung von O2 mit Lumineszenzsonden Isotopenselektive Bestimmung von CO2 mit TDLAS Optische Charakterisierung stark streuender Materialien mit Photonendichtewellen}, language = {de} } @misc{PeterBoldtNiedersteinetal.1990, author = {Peter, Martin G. and Boldt, Peter C. and Niederstein, Yvonne and Peter-Katalinić, Jasna}, title = {Synthesen von Galactose-Cluster-haltigen Steroid-Derivaten}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-16783}, year = {1990}, abstract = {The synthesis of galactose clusters that are linked to a steroid moiety by a peptide-like spacer unit is described. The galactose cluster is obtained by Koenigs-Knorr glycosylation of TRIS-Gly-Fmoc (2b) under Helferich conditions. Peptide and ester bonds are formed after activation of carboxylic acids as diphenylthiophene dioxide (TDO) esters. 6a is synthesized in a convergent way by coupling of (Ac4Gal)3-TRIS-Gly (3e) with cholesteryl TDO succinate (5b). Coupling of (Ac4Gal)3-TRIS-Gly hydrogen succinate (3f) with Gly-O-Chol (5d) by means of EEDQ yields 6d. Reaction of (Ac4Gal)3-TRIS-Gly-SUCC-O-TDO (3g) with 25-hydroxycholesterol leads in a linear sequence to the oxysterol derivative 6f. Selective cleavage of the acetyl groups from galactose units yields the known compound 6b and the new derivatives 6e and 6g.}, language = {de} } @misc{PeterAndersenHartmannetal.1992, author = {Peter, Martin G. and Andersen, Svend Olav and Hartmann, Rudolf and Miessner, Merle and Roepstorff, Peter}, title = {Catecholamine-protein conjugates : isolation of 4-phenylphenoxazin-2-ones from oxidative coupling of N-acetyldopamine with alipathic amino acids}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-17571}, year = {1992}, abstract = {4-Phenylphenoxazinones were isolated after biomimetic oxidation, using diphenoloxidases of insect cuticle, mushroom tyrosinase, or after autoxidation of N-acetyldopamine (Image ) in the presence of β-alanine, β-alanine methyl ester or N-acetyl-L-lysine. They are formed presumably by addition of 2-aminoalkyl-5-alkylphenols to the o-quinone of biphenyltetrol which, in turn, arises from oxidative coupling of. The structures of present the first examples for the assembly of reasonably stable intermediates in the rather complex process of chemical modifications of aliphatic amino acid residues by o-quinones.}, language = {en} } @misc{LaschewskyRingsdorf1988, author = {Laschewsky, Andr{\´e} and Ringsdorf, H.}, title = {Polymerization of amphiphilic dienes in Langmuir-Blodgett multilayers}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-17176}, year = {1988}, abstract = {Amphiphilic derivatives of octadiene and docosadiene were investigated in monolayers and Langmuir-Blodgett multilayers, with respect to their self-organization and their polymerization behavior. All amphiphiles investigated form monolayers. However, only acid and alcohol derivatives were able to build up multilayers. Those multilayers are rapidly photopolymerized in the layers via a two-step process: Irradiation with long-wavelength UV light yields soluble polymers, whereas additional irradiation with sfiort-wavelength UV light produces insoluble and presumably cross-linked polymers. The reaction meclianism is discussed according to the polymer characterization by UV spectroscopy, small-angle X-ray scattering, NMR spectroscopy, and gel permeation chromatography. All multilayers undergo structural changes during the polymerization; substantial changes result in defects in the polymerized layers as observed by scanning electron microscopy. In contrast to the acids and alcohols, the deposition of monolayers of the aldehyde derivatives did not yield well-ordered multilayers, but rather amorphous films. In this different film structure, the photopolymerization process differs from the one observed in multilayers.}, language = {en} } @misc{PeterStuppLentes1983, author = {Peter, Martin G. and Stupp, Hans-Peter and Lentes, Klaus-Ulrich}, title = {Umkehr der Enantioselektivit{\"a}t bei der enzymatischen Hydrolyse von Juvenilhormon als Ergebnis einer Proteinfraktionierung}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-17001}, year = {1983}, abstract = {Aus dem Inhalt: Die Juvenilhormone 1a-c werden im Blut von Insekten enzymatisch zu den biologisch inaktiven Sluren hydrolysiert. Bei der Hydrolyse von racemischem 1c im Blut der Wanderheuschrecke Locusta migratoria wird ein Umsatz von 40-60\% erreicht. Das unumgesetzte Edukt enth{\"a}llt einen {\"U}berschuß an nat{\"u}rlich konfiguriertem (10R)-1c (e.e. 47.2\%). Wir konnten zeigen, daß das in der H{\"a}molymphe vorhandene Hormon-Bindungsprotein bevorzugt mit (10R)- 1c assoziiert.}, language = {de} }