@article{FreitasdaCruzPfahringerMartensenetal.2021, author = {Freitas da Cruz, Harry and Pfahringer, Boris and Martensen, Tom and Schneider, Frederic and Meyer, Alexander and B{\"o}ttinger, Erwin and Schapranow, Matthieu-Patrick}, title = {Using interpretability approaches to update "black-box" clinical prediction models}, series = {Artificial intelligence in medicine : AIM}, volume = {111}, journal = {Artificial intelligence in medicine : AIM}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0933-3657}, doi = {10.1016/j.artmed.2020.101982}, pages = {13}, year = {2021}, abstract = {Despite advances in machine learning-based clinical prediction models, only few of such models are actually deployed in clinical contexts. Among other reasons, this is due to a lack of validation studies. In this paper, we present and discuss the validation results of a machine learning model for the prediction of acute kidney injury in cardiac surgery patients initially developed on the MIMIC-III dataset when applied to an external cohort of an American research hospital. To help account for the performance differences observed, we utilized interpretability methods based on feature importance, which allowed experts to scrutinize model behavior both at the global and local level, making it possible to gain further insights into why it did not behave as expected on the validation cohort. The knowledge gleaned upon derivation can be potentially useful to assist model update during validation for more generalizable and simpler models. We argue that interpretability methods should be considered by practitioners as a further tool to help explain performance differences and inform model update in validation studies.}, language = {en} } @book{AdrianoBleifussChengetal.2019, author = {Adriano, Christian and Bleifuß, Tobias and Cheng, Lung-Pan and Diba, Kiarash and Fricke, Andreas and Grapentin, Andreas and Jiang, Lan and Kovacs, Robert and Krejca, Martin Stefan and Mandal, Sankalita and Marwecki, Sebastian and Matthies, Christoph and Mattis, Toni and Niephaus, Fabio and Pirl, Lukas and Quinzan, Francesco and Ramson, Stefan and Rezaei, Mina and Risch, Julian and Rothenberger, Ralf and Roumen, Thijs and Stojanovic, Vladeta and Wolf, Johannes}, title = {Technical report}, number = {129}, editor = {Meinel, Christoph and Plattner, Hasso and D{\"o}llner, J{\"u}rgen Roland Friedrich and Weske, Mathias and Polze, Andreas and Hirschfeld, Robert and Naumann, Felix and Giese, Holger and Baudisch, Patrick and Friedrich, Tobias and B{\"o}ttinger, Erwin and Lippert, Christoph}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-465-4}, issn = {1613-5652}, doi = {10.25932/publishup-42753}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-427535}, publisher = {Universit{\"a}t Potsdam}, pages = {vi, 267}, year = {2019}, abstract = {Design and Implementation of service-oriented architectures imposes a huge number of research questions from the fields of software engineering, system analysis and modeling, adaptability, and application integration. Component orientation and web services are two approaches for design and realization of complex web-based system. Both approaches allow for dynamic application adaptation as well as integration of enterprise application. Commonly used technologies, such as J2EE and .NET, form de facto standards for the realization of complex distributed systems. Evolution of component systems has lead to web services and service-based architectures. This has been manifested in a multitude of industry standards and initiatives such as XML, WSDL UDDI, SOAP, etc. All these achievements lead to a new and promising paradigm in IT systems engineering which proposes to design complex software solutions as collaboration of contractually defined software services. Service-Oriented Systems Engineering represents a symbiosis of best practices in object-orientation, component-based development, distributed computing, and business process management. It provides integration of business and IT concerns. The annual Ph.D. Retreat of the Research School provides each member the opportunity to present his/her current state of their research and to give an outline of a prospective Ph.D. thesis. Due to the interdisciplinary structure of the research school, this technical report covers a wide range of topics. These include but are not limited to: Human Computer Interaction and Computer Vision as Service; Service-oriented Geovisualization Systems; Algorithm Engineering for Service-oriented Systems; Modeling and Verification of Self-adaptive Service-oriented Systems; Tools and Methods for Software Engineering in Service-oriented Systems; Security Engineering of Service-based IT Systems; Service-oriented Information Systems; Evolutionary Transition of Enterprise Applications to Service Orientation; Operating System Abstractions for Service-oriented Computing; and Services Specification, Composition, and Enactment.}, language = {en} } @article{BorchertMockTomczaketal.2021, author = {Borchert, Florian and Mock, Andreas and Tomczak, Aurelie and H{\"u}gel, Jonas and Alkarkoukly, Samer and Knurr, Alexander and Volckmar, Anna-Lena and Stenzinger, Albrecht and Schirmacher, Peter and Debus, J{\"u}rgen and J{\"a}ger, Dirk and Longerich, Thomas and Fr{\"o}hling, Stefan and Eils, Roland and Bougatf, Nina and Sax, Ulrich and Schapranow, Matthieu-Patrick}, title = {Knowledge bases and software support for variant interpretation in precision oncology}, series = {Briefings in bioinformatics}, volume = {22}, journal = {Briefings in bioinformatics}, number = {6}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {1467-5463}, doi = {10.1093/bib/bbab134}, pages = {17}, year = {2021}, abstract = {Precision oncology is a rapidly evolving interdisciplinary medical specialty. Comprehensive cancer panels are becoming increasingly available at pathology departments worldwide, creating the urgent need for scalable cancer variant annotation and molecularly informed treatment recommendations. A wealth of mainly academia-driven knowledge bases calls for software tools supporting the multi-step diagnostic process. We derive a comprehensive list of knowledge bases relevant for variant interpretation by a review of existing literature followed by a survey among medical experts from university hospitals in Germany. In addition, we review cancer variant interpretation tools, which integrate multiple knowledge bases. We categorize the knowledge bases along the diagnostic process in precision oncology and analyze programmatic access options as well as the integration of knowledge bases into software tools. The most commonly used knowledge bases provide good programmatic access options and have been integrated into a range of software tools. For the wider set of knowledge bases, access options vary across different parts of the diagnostic process. Programmatic access is limited for information regarding clinical classifications of variants and for therapy recommendations. The main issue for databases used for biological classification of pathogenic variants and pathway context information is the lack of standardized interfaces. There is no single cancer variant interpretation tool that integrates all identified knowledge bases. Specialized tools are available and need to be further developed for different steps in the diagnostic process.}, language = {en} } @article{VitaglianoHameedJiangetal.2023, author = {Vitagliano, Gerardo and Hameed, Mazhar and Jiang, Lan and Reisener, Lucas and Wu, Eugene and Naumann, Felix}, title = {Pollock: a data loading benchmark}, series = {Proceedings of the VLDB Endowment}, volume = {16}, journal = {Proceedings of the VLDB Endowment}, number = {8}, publisher = {Association for Computing Machinery}, address = {New York}, issn = {2150-8097}, doi = {10.14778/3594512.3594518}, pages = {1870 -- 1882}, year = {2023}, abstract = {Any system at play in a data-driven project has a fundamental requirement: the ability to load data. The de-facto standard format to distribute and consume raw data is CSV. Yet, the plain text and flexible nature of this format make such files often difficult to parse and correctly load their content, requiring cumbersome data preparation steps. We propose a benchmark to assess the robustness of systems in loading data from non-standard CSV formats and with structural inconsistencies. First, we formalize a model to describe the issues that affect real-world files and use it to derive a systematic lpollutionz process to generate dialects for any given grammar. Our benchmark leverages the pollution framework for the csv format. To guide pollution, we have surveyed thousands of real-world, publicly available csv files, recording the problems we encountered. We demonstrate the applicability of our benchmark by testing and scoring 16 different systems: popular csv parsing frameworks, relational database tools, spreadsheet systems, and a data visualization tool.}, language = {en} } @inproceedings{MarxBruenkerMirbabaieetal.2024, author = {Marx, Julian and Br{\"u}nker, Felix and Mirbabaie, Milad and Stieglitz, Stefan}, title = {Digital activism on social media}, series = {Proceedings of the 57th Annual Hawaii International Conference on System Sciences}, booktitle = {Proceedings of the 57th Annual Hawaii International Conference on System Sciences}, editor = {Bui, Tung X.}, publisher = {Department of IT Management Shidler College of Business University of Hawaii}, address = {Honolulu, HI}, isbn = {978-0-99813-317-1}, pages = {7205 -- 7214}, year = {2024}, abstract = {Social media constitute an important arena for public debates and steady interchange of issues relevant to society. To boost their reputation, commercial organizations also engage in political, social, or environmental debates on social media. To engage in this type of digital activism, organizations increasingly utilize the social media profiles of executive employees and other brand ambassadors. However, the relationship between brand ambassadors' digital activism and corporate reputation is only vaguely understood. The results of a qualitative inquiry suggest that digital activism via brand ambassadors can be risky (e.g., creating additional surface for firestorms, financial loss) and rewarding (e.g., emitting authenticity, employing 'megaphones' for industry change) at the same time. The paper informs both scholarship and practitioners about strategic trade-offs that need to be considered when employing brand ambassadors for digital activism.}, language = {en} } @article{FandinoLaferriereRomeroetal.2021, author = {Fandi{\~n}o, Jorge and Laferriere, Francois and Romero, Javier and Schaub, Torsten H. and Son, Tran Cao}, title = {Planning with incomplete information in quantified answer set programming}, series = {Theory and practice of logic programming}, volume = {21}, journal = {Theory and practice of logic programming}, number = {5}, publisher = {Cambridge University Press}, address = {Cambridge}, issn = {1471-0684}, doi = {10.1017/S1471068421000259}, pages = {663 -- 679}, year = {2021}, abstract = {We present a general approach to planning with incomplete information in Answer Set Programming (ASP). More precisely, we consider the problems of conformant and conditional planning with sensing actions and assumptions. We represent planning problems using a simple formalism where logic programs describe the transition function between states, the initial states and the goal states. For solving planning problems, we use Quantified Answer Set Programming (QASP), an extension of ASP with existential and universal quantifiers over atoms that is analogous to Quantified Boolean Formulas (QBFs). We define the language of quantified logic programs and use it to represent the solutions different variants of conformant and conditional planning. On the practical side, we present a translation-based QASP solver that converts quantified logic programs into QBFs and then executes a QBF solver, and we evaluate experimentally the approach on conformant and conditional planning benchmarks.}, language = {en} } @inproceedings{MirbabaieRieskampHofeditzetal.2024, author = {Mirbabaie, Milad and Rieskamp, Jonas and Hofeditz, Lennart and Stieglitz, Stefan}, title = {Breaking down barriers}, series = {Proceedings of the 57th Annual Hawaii International Conference on System Sciences}, booktitle = {Proceedings of the 57th Annual Hawaii International Conference on System Sciences}, editor = {Bui, Tung X.}, publisher = {Department of IT Management Shidler College of Business University of Hawaii}, address = {Honolulu, HI}, isbn = {978-0-99813-317-1}, pages = {672 -- 681}, year = {2024}, abstract = {Many researchers hesitate to provide full access to their datasets due to a lack of knowledge about research data management (RDM) tools and perceived fears, such as losing the value of one's own data. Existing tools and approaches often do not take into account these fears and missing knowledge. In this study, we examined how conversational agents (CAs) can provide a natural way of guidance through RDM processes and nudge researchers towards more data sharing. This work offers an online experiment in which researchers interacted with a CA on a self-developed RDM platform and a survey on participants' data sharing behavior. Our findings indicate that the presence of a guiding and enlightening CA on an RDM platform has a constructive influence on both the intention to share data and the actual behavior of data sharing. Notably, individual factors do not appear to impede or hinder this effect.}, language = {en} } @article{XinYingTiberiusAlnooretal.2024, author = {XinYing, Chew and Tiberius, Victor and Alnoor, Alhamzah and Camilleri, Mark and Khaw, Khai Wah}, title = {The dark side of metaverse: a multi-perspective of deviant behaviors from PLS-SEM and fsQCA findings}, series = {International journal of human-computer interaction}, journal = {International journal of human-computer interaction}, publisher = {Taylor \& Francis}, address = {London}, issn = {1044-7318}, doi = {10.1080/10447318.2024.2331875}, pages = {21}, year = {2024}, abstract = {The metaverse has created a huge buzz of interest because such a phenomenon is emerging. The behavioral aspect of the metaverse includes user engagement and deviant behaviors in the metaverse. Such technology has brought various dangers to individuals and society. There are growing cases reported of sexual abuse, racism, harassment, hate speech, and bullying because of online disinhibition make us feel more relaxed. This study responded to the literature call by investigating the effect of technical and social features through mediating roles of security and privacy on deviant behaviors in the metaverse. The data collected from virtual network users reached 1121 respondents. Partial Least Squares based structural equation modeling (PLS-SEM) and fuzzy set Qualitative Comparative Analysis (fsQCA) were used. PLS-SEM results revealed that social features such as user-to-user interaction, homophily, social ties, and social identity, and technical design such as immersive experience and invisibility significantly affect users' deviant behavior in the metaverse. The fsQCA results provided insights into the multiple causal solutions and configurations. This study is exceptional because it provided decisive results by understanding the deviant behavior of users based on the symmetrical and asymmetrical approach to virtual networks.}, language = {en} }