@misc{MangelsdorfHornConradBagdahnetal.2011,
  author    = {Mangelsdorf, Birgit and Horn-Conrad, Antje and Bagdahn, Christian and Schmidt, Bernd and Eckardt, Barbara and G{\"o}rlich, Petra and Peter, Andreas and P{\"o}sl, Thomas and Nestler, Ralf and Zimmermann, Matthias},
  title     = {Portal = Wenn die Chemie stimmt: L{\"o}sungen f{\"u}r heute und morgen},
  series = {Das Potsdamer Universit{\"a}tsmagazin},
  journal   = {Das Potsdamer Universit{\"a}tsmagazin},
  number    = {03/2011},
  organization    = {Universit{\"a}t Potsdam, Referat f{\"u}r Presse- und {\"O}ffentlichkeitsarbeit},
  issn      = {1618-6893},
  doi       = {10.25932/publishup-45981},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-459810},
  pages     = {43},
  year      = {2011},
  abstract  = {Aus dem Inhalt: - Wenn die Chemie stimmt: L{\"o}sungen f{\"u}r heute und morgen - Das Kreuz mit dem Kreuz - „Das verr{\"u}ckteste Jahr unseres Lebens"},
  language  = {de}
}
@article{WalzZimmermannSeidl1994,
  author    = {Walz, Bernd and Zimmermann, Bernhard and Seidl, Siegfried},
  title     = {Intracellular Ca2+ concentration and latency of light-induced Ca2+ changes in photoreceptors of the honeybee drone},
  year      = {1994},
  language  = {en}
}
@article{ReinZimmermannHilleetal.2006,
  author    = {Rein, Julia and Zimmermann, Bernhard and Hille, Carsten and Lang, Ingo and Walz, Bernd and Baumann, Otto},
  title     = {Fluorescence measurements of serotonin-induced V-ATPase-dependent pH changes at the luminal surface in salivary glands of the blowfly Calliphora vicina},
  issn      = {0022-0949},
  doi       = {10.1242/Jeb.02187},
  year      = {2006},
  abstract  = {Secretion in blowfly salivary glands is induced by the neurohormone serotonin and powered by a vacuolar-type H+- ATPase (V-ATPase) located in the apical membrane of the secretory cells. We have established a microfluorometric method for analysing pH changes at the luminal surface of the secretory epithelial cells by using the fluorescent dye 5-N- hexadecanoyl-aminofluorescein (HAF). After injection of HAF into the lumen of the tubular salivary gland, the fatty acyl chain of the dye molecule partitions into the outer leaflet of the plasma membrane and its pH-sensitive fluorescent moiety is exposed at the cell surface. Confocal imaging has confirmed that HAF distributes over the entire apical membrane of the secretory cells and remains restricted to this membrane domain. Ratiometric analysis of HAF fluorescence demonstrates that serotonin leads to a reversible dose-dependent acidification at the luminal surface. Inhibition by concanamycin A confirms that the serotonin-induced acidification at the luminal surface is due to H+ transport across the apical membrane via V-ATPase. Measurements with pH-sensitive microelectrodes corroborate a serotonin-induced luminal acidification and demonstrate that luminal pH decreases by about 0.4 pH units at saturating serotonin concentrations. We conclude that ratiometric measurements of HAF fluorescence provide an elegant method for monitoring V-ATPase-dependent H+ transport in the blowfly salivary gland in vivo and for analysing the spatiotemporal pattern of pH changes at the luminal surface},
  language  = {en}
}
@article{WalzBaumannZimmermannetal.1995,
  author    = {Walz, Bernd and Baumann, Otto and Zimmermann, Bernhard and Ciriacy-Wantrup, E.v.},
  title     = {Caffeine- and ryanodine-sensitive Ca2+-induced Ca2+ release from the endo plasmatic reticulum in honeybee photoreceptors},
  year      = {1995},
  language  = {en}
}
@article{ZimmermannWalz1997,
  author    = {Zimmermann, Bernhard and Walz, Bernd},
  title     = {Serotonin-induced intercellular calcium waves in salivary glands of the blowfley Calliphora erythrocephala},
  year      = {1997},
  language  = {en}
}
@article{WalzUkhanovZimmermann2000,
  author    = {Walz, Bernd and Ukhanov, Kyrill and Zimmermann, Bernhard},
  title     = {Actions of neomycin on electrical light responses : Ca2+ release and intracellular Ca2+ changes in photoreceptors of the honeybee drone},
  issn      = {0340-7594},
  year      = {2000},
  language  = {en}
}
@article{ZimmermannWalz1999,
  author    = {Zimmermann, Bernhard and Walz, Bernd},
  title     = {The mechanism mediating regenerative intercellular Ca2+ waves in the blowfly salivary gland},
  year      = {1999},
  language  = {en}
}
@misc{MuellerRoeberZimmermannEckardtetal.2015,
  author    = {M{\"u}ller-R{\"o}ber, Bernd and Zimmermann, Matthias and Eckardt, Barbara and J{\"a}ger, Heidi and Kampe, Heike and Horn-Conrad, Antje and J{\"a}ger, Sophie},
  title     = {Portal Wissen = Paths},
  number    = {01/2015},
  organization    = {University of Potsdam, Press and Public Relations Department},
  issn      = {2198-9974},
  doi       = {10.25932/publishup-44150},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-441506},
  pages     = {55},
  year      = {2015},
  abstract  = {How traits are inherited from one generation to the next, how mutations change genetic information and consequently contribute to the development of new characteristics and emergence of new species - all these are exciting biological questions. Over millions of years, genetic differentiation has brought about an incredible diversity of species. Evolution has followed many different paths. It has led to an awesome natural biodiversity - to organisms that have adapted to very different environments and are sometimes oddly shaped or behave strangely. Humanmade biodiversity is stunning, too. Just think of the 10,000 rose varieties whose beauty delights, or the myriad wheat, barley, and corn variations; plants that had all once been plain grasses feed us today. We humans create our own biodiversity unknown to nature. And it is serving us well. Thanks to genome research we are now able to read the complete genetic information of organisms within a few hours or days. It takes much longer, however, to functionally map the many genomic sequences. Researchers achieve this through various methods: Activating or deactivating genes systematically, modifying their code, and exchanging genetic information between organisms have become standard procedures worldwide. The path to knowledge is often intricate, though. Elaborate experimental approaches are often necessary to gain insight into biological processes. Methods of genomic research enable us to investigate not only what is "out there" in nature, but also to ask, "How does a living organism, like a moss, react when sent to the International Space Station (ISS)? Can we gain knowledge about the adaptation strategies of living beings in harsh environmental conditions or even for colonizing the Moon or Mars?" Can we use synthetic biology to precisely alter microorganisms, planned on a drawing board so to speak, to create new options for treating diseases or for making innovative biology-based products? The answer to both questions is a resounding Yes! (Although moving to other planets is not on our present agenda.) Human land use determines biodiversity. On the other hand, organisms influence the formation of landscapes and, sooner or later, the composition of our atmosphere. This also leads to exciting scientific questions. Researchers have to strike new paths to reach new conclusions. Paths often cross other paths. A few years ago it was still unforeseeable that ecological research would substantially benefit from fast DNA sequencing methods. Genome researchers could hardly assume that the same techniques would lead to new possibilities for examining the highly complex cellular regulation and optimizing biotechnological processes. You will find examples of the multi-faceted research in biology as well as other very interesting articles in the latest edition of Portal Wissen. I wish you an enjoyable read! Prof. Dr. Bernd M{\"u}ller-R{\"o}ber Professor of Molecular Biology},
  language  = {en}
}
@misc{GraefSecklerHagemannetal.2012,
  author    = {Gr{\"a}f, Ralph and Seckler, Robert and Hagemann, Alfred and D'Aprile, Iwan-Michelangelo and Schulte, Christoph and Zimmermann, Matthias and Blom, Hans and Horn-Conrad, Antje and Kampe, Heike and J{\"a}ger, Sophie and Haase, Jana and Eckardt, Barbara and Priebs-Tr{\"o}ger, Astrid and Walz, Bernd},
  title     = {Portal Wissen = Raum},
  number    = {01/2012},
  organization    = {Universit{\"a}t Potsdam, Referat f{\"u}r Presse- und {\"O}ffentlichkeitsarbeit},
  issn      = {2194-4237},
  doi       = {10.25932/publishup-44078},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-440785},
  pages     = {98},
  year      = {2012},
  abstract  = {Mit „Portal Wissen" laden wir Sie ein, die Forschung an der Universit{\"a}t Potsdam zu entdecken und in ihrer Vielfalt kennenzulernen. In der ersten Ausgabe dreht sich alles um „R{\"a}ume". R{\"a}ume, in denen geforscht wird, solche, die es zu erforschen gilt, andere, die durch Wissenschaft zug{\"a}nglich oder erschlossen werden, aber auch R{\"a}ume, die Wissenschaft braucht, um sich entfalten zu k{\"o}nnen. Forschung vermisst R{\"a}ume: „Wissenschaft wird von Menschen gemacht", schrieb der Physiker Werner Heisenberg. Umgekehrt l{\"a}sst sich sagen: Wissenschaft macht Menschen, widmet sich ihnen, beeinflusst sie. Dieser Beziehung ist „Portal Wissen" nachgegangen. Wir haben Wissenschaftler getroffen, sie gefragt, wie aus ihren Fragen Projekte entstehen, haben sie auf dem oft verschlungenen Weg zum Ziel begleitet. Ein besonderes Augenmerk dieses Heftes gilt den „Kulturellen Begegnungsr{\"a}umen", denen ein eigener Profilbereich der Forschung an der Universit{\"a}t Potsdam gewidmet ist. Forschung hat R{\"a}ume: Labore, Bibliotheken, Gew{\"a}chsh{\"a}user oder Archive - hier ist Wissenschaft zu Liebe Leserinnen und Leser, Hause. All diese Orte sind so einzigartig wie die Wissenschaftler, die in ihnen arbeiten, oder die Untersuchungen, die hier stattfinden. Erst die Vision davon, wie ein Problem zu l{\"o}sen ist, macht aus einfachen Zimmern „Laborr{\"a}ume". Wir haben ihre T{\"u}ren ge{\"o}ffnet, um zu zeigen, was - und wer - sich dahinter befindet. Forschung er{\"o}ffnet R{\"a}ume: Wenn Wissenschaft erfolgreich ist, bewegt sie uns, bringt uns voran. Auf dem Weg einer wissenschaftlichen Erkenntnis aus dem Labor in den Alltag stehen mitunter H{\"u}rden, die meist nicht auf den ersten Blick zu erkennen sind. Auf jeden Fall aber ist ihre Anwendung erster Ausgangspunkt von Wissenschaft, Antrieb und Motivation jedes Forschers. „Portal Wissen" zeigt, welche „Praxisr{\"a}ume" sich aus der {\"U}bersetzung von Forschungsresultaten ergeben. Dort, wo wir es unbedingt erwarten, und dort, wo vielleicht nicht. Forschung erschließt R{\"a}ume: Bei Expeditionen, Feldversuchen und Exkursionen wird nahezu jede Umgebung zum mobilen Labor. So er{\"o}ffnet Wissenschaft Zug{\"a}nge auch zu Orten, die auf vielfach andere Weise verschlossen oder unzug{\"a}nglich scheinen. Wir haben uns in Forscher- Reisetaschen gemogelt, um bei Entdeckungsreisen dabei zu sein, die weit weg - vor allem nach Afrika - f{\"u}hren. Zugleich haben wir beobachtet, wie „Entwicklungsr{\"a}ume" sich auch von Potsdam aus erschließen lassen oder zumindest ihre Vermessung in Potsdam beginnen kann. Forschung braucht R{\"a}ume: Wissenschaft hat zwei Geschlechter, endlich. Noch nie waren so viele Frauen in der Forschung t{\"a}tig wie derzeit. Ein Grund zum Ausruhen ist dies gleichwohl nicht. Deutschlandweit ist aktuell nur jede f{\"u}nfte Professur von einer Frau besetzt. „Portal Wissen" schaut, welche „Entwicklungsr{\"a}ume" Frauen sich in der Wissenschaft, aber auch dar{\"u}ber hinaus geschaffen haben. Und wo sie ihnen verwehrt werden. Wir w{\"u}nschen Ihnen eine anregende Lekt{\"u}re und dass auch Sie einen Raum finden, der Sie inspiriert. Prof. Dr. Robert Seckler Vizepr{\"a}sident f{\"u}r Forschung und wissenschaftlichen Nachwuchs},
  language  = {de}
}
@misc{DeekenReichertZechetal.,
  author    = {Deeken, Friederike and Reichert, Markus and Zech, Hilmar and Wenzel, Julia and Wedemeyer, Friederike and Aguilera, Alvaro and Aslan, Acelya and Bach, Patrick and Bahr, Nadja Samia and Ebrahimi, Claudia and Fischbach, Pascale Christine and Ganz, Marvin and Garbusow, Maria and Großkopf, Charlotte M. and Heigert, Marie and Hentschel, Angela and Karl, Damian and Pelz, Patricia and Pinger, Mathieu and Riemerschmid, Carlotta and Rosenthal, Annika and Steffen, Johannes and Strehle, Jens and Weiss, Franziska and Wieder, Gesine and Wieland, Alfred and Zaiser, Judith and Zimmermann, Sina and Walter, Henrik and Lenz, Bernd and Deserno, Lorenz and Smolka, Michael N. and Liu, Shuyan and Ebner-Priemer, Ulrich Walter and Heinz, Andreas and Rapp, Michael A.},
  title     = {Patterns of Alcohol Consumption Among Individuals With Alcohol Use Disorder During the COVID-19 Pandemic and Lockdowns in Germany},
  series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  journal   = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  number    = {805},
  issn      = {1866-8364},
  doi       = {10.25932/publishup-57146},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-571460},
  pages     = {11},
  abstract  = {Importance Alcohol consumption (AC) leads to death and disability worldwide. Ongoing discussions on potential negative effects of the COVID-19 pandemic on AC need to be informed by real-world evidence. Objective To examine whether lockdown measures are associated with AC and consumption-related temporal and psychological within-person mechanisms. Design, Setting, and Participants This quantitative, intensive, longitudinal cohort study recruited 1743 participants from 3 sites from February 20, 2020, to February 28, 2021. Data were provided before and within the second lockdown of the COVID-19 pandemic in Germany: before lockdown (October 2 to November 1, 2020); light lockdown (November 2 to December 15, 2020); and hard lockdown (December 16, 2020, to February 28, 2021). Main Outcomes and Measures Daily ratings of AC (main outcome) captured during 3 lockdown phases (main variable) and temporal (weekends and holidays) and psychological (social isolation and drinking intention) correlates. Results Of the 1743 screened participants, 189 (119 [63.0\%] male; median [IQR] age, 37 [27.5-52.0] years) with at least 2 alcohol use disorder (AUD) criteria according to the Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) yet without the need for medically supervised alcohol withdrawal were included. These individuals provided 14 694 smartphone ratings from October 2020 through February 2021. Multilevel modeling revealed significantly higher AC (grams of alcohol per day) on weekend days vs weekdays (β = 11.39; 95\% CI, 10.00-12.77; P < .001). Alcohol consumption was above the overall average on Christmas (β = 26.82; 95\% CI, 21.87-31.77; P < .001) and New Year's Eve (β = 66.88; 95\% CI, 59.22-74.54; P < .001). During the hard lockdown, perceived social isolation was significantly higher (β = 0.12; 95\% CI, 0.06-0.15; P < .001), but AC was significantly lower (β = -5.45; 95\% CI, -8.00 to -2.90; P = .001). Independent of lockdown, intention to drink less alcohol was associated with lower AC (β = -11.10; 95\% CI, -13.63 to -8.58; P < .001). Notably, differences in AC between weekend and weekdays decreased both during the hard lockdown (β = -6.14; 95\% CI, -9.96 to -2.31; P = .002) and in participants with severe AUD (β = -6.26; 95\% CI, -10.18 to -2.34; P = .002). Conclusions and Relevance This 5-month cohort study found no immediate negative associations of lockdown measures with overall AC. Rather, weekend-weekday and holiday AC patterns exceeded lockdown effects. Differences in AC between weekend days and weekdays evinced that weekend drinking cycles decreased as a function of AUD severity and lockdown measures, indicating a potential mechanism of losing and regaining control. This finding suggests that temporal patterns and drinking intention constitute promising targets for prevention and intervention, even in high-risk individuals.},
  language  = {en}
}