@article{RusconiVallerianiDunlopetal.2012, author = {Rusconi, Marco and Valleriani, Angelo and Dunlop, John William Chapman and Kurths, J{\"u}rgen and Weinkamer, Richard}, title = {Quantitative approach to the stochastics of bone remodeling}, series = {epl : a letters journal exploring the frontiers of physics}, volume = {97}, journal = {epl : a letters journal exploring the frontiers of physics}, number = {2}, publisher = {EDP Sciences}, address = {Mulhouse}, issn = {0295-5075}, doi = {10.1209/0295-5075/97/28009}, pages = {6}, year = {2012}, abstract = {During life bones constantly adapt their structure to their mechanical environment via a mechanically controlled process called bone remodeling. For trabecular bone, this process modifies the thickness of each trabecula leading occasionally to full resorption. We describe the irreversible dynamics of the trabecular thickness distribution (TTD) by means of a Markov chain discrete in space and time. By using thickness data from adult patients, we derive the transition probabilities in the chain. This allows a quantification, in terms of geometrical quantities, of the control of bone remodeling and thus to determine the evolution of the TTD with age.}, language = {en} } @article{RusconiVallerianiDunlopetal.2009, author = {Rusconi, Marco and Valleriani, Angelo and Dunlop, John William Chapman and Kurths, J{\"u}rgen and Weinkamer, Richard}, title = {Insights into the control of trabecular bone remodelling obtained by a Markov model}, issn = {8756-3282}, doi = {10.1016/j.bone.2009.03.467}, year = {2009}, language = {en} } @article{DelormeDuboisGarnieretal.2006, author = {Delorme, Nicolas and Dubois, Monique and Garnier, Sebastien and Laschewsky, Andr{\´e} and Weinkamer, Richard and Zemb, Thomas and Fery, Andreas}, title = {Surface immobilization and mechanical properties of catanionic hollow faceted polyhedrons}, issn = {1520-1758}, doi = {10.1021/Jp054473+}, year = {2006}, abstract = {We report here for the first time on surface immobilization of hollow faceted polyhedrons formed from catanionic surfactant mixtures. We find that electrostatic interaction with the substrate dominates their adhesion behavior. Using polyelectrolyte coated surfaces with tailored charge densities, polyhedrons can thus be immobilized without complete spreading, which allows for further study of their mechanical properties using AFM force measurements. The elastic response of individual polyhedrons can be locally resolved, showing pronounced differences in stiffness between faces and vertexes of the structure, which makes these systems interesting as models for structurally similar colloidal scale objects such as viruses, where such effects are predicted but cannot be directly observed due to the smaller dimensions. Elastic constants of the wall material are estimated using shell and plate deformation models and are found to be a factor of 5 larger than those for neutral lipidic bilayers in the gel state. We discuss the molecular origins of this high stiffness}, language = {en} }